Amino acid dipepetide frequency for Pochonia chlamydosporia 123

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.268AlaAla: 9.268 ± 0.05	1.134AlaCys: 1.134 ± 0.016	4.331AlaAsp: 4.331 ± 0.028	4.96AlaGlu: 4.96 ± 0.041	3.207AlaPhe: 3.207 ± 0.028	5.887AlaGly: 5.887 ± 0.039	1.716AlaHis: 1.716 ± 0.019	4.503AlaIle: 4.503 ± 0.03	4.385AlaLys: 4.385 ± 0.032	7.645AlaLeu: 7.645 ± 0.047	2.127AlaMet: 2.127 ± 0.021	3.145AlaAsn: 3.145 ± 0.023	4.418AlaPro: 4.418 ± 0.036	3.34AlaGln: 3.34 ± 0.024	4.626AlaArg: 4.626 ± 0.031	7.156AlaSer: 7.156 ± 0.04	5.41AlaThr: 5.41 ± 0.031	5.59AlaVal: 5.59 ± 0.037	1.205AlaTrp: 1.205 ± 0.015	2.161AlaTyr: 2.161 ± 0.018	0.018AlaXaa: 0.018 ± 0.002
Cys	0.993CysAla: 0.993 ± 0.014	0.252CysCys: 0.252 ± 0.007	0.719CysAsp: 0.719 ± 0.011	0.597CysGlu: 0.597 ± 0.01	0.555CysPhe: 0.555 ± 0.011	1.002CysGly: 1.002 ± 0.014	0.346CysHis: 0.346 ± 0.008	0.719CysIle: 0.719 ± 0.011	0.574CysLys: 0.574 ± 0.011	1.271CysLeu: 1.271 ± 0.017	0.282CysMet: 0.282 ± 0.007	0.48CysAsn: 0.48 ± 0.01	0.693CysPro: 0.693 ± 0.012	0.48CysGln: 0.48 ± 0.01	0.777CysArg: 0.777 ± 0.012	0.93CysSer: 0.93 ± 0.013	0.725CysThr: 0.725 ± 0.011	0.832CysVal: 0.832 ± 0.014	0.222CysTrp: 0.222 ± 0.007	0.367CysTyr: 0.367 ± 0.01	0.002CysXaa: 0.002 ± 0.001
Asp	4.927AspAla: 4.927 ± 0.03	0.676AspCys: 0.676 ± 0.009	4.433AspAsp: 4.433 ± 0.039	4.523AspGlu: 4.523 ± 0.035	2.232AspPhe: 2.232 ± 0.021	4.392AspGly: 4.392 ± 0.029	1.25AspHis: 1.25 ± 0.015	3.177AspIle: 3.177 ± 0.023	2.752AspLys: 2.752 ± 0.025	4.967AspLeu: 4.967 ± 0.032	1.421AspMet: 1.421 ± 0.017	2.033AspAsn: 2.033 ± 0.018	3.036AspPro: 3.036 ± 0.022	1.914AspGln: 1.914 ± 0.02	2.943AspArg: 2.943 ± 0.025	4.124AspSer: 4.124 ± 0.03	3.053AspThr: 3.053 ± 0.024	3.942AspVal: 3.942 ± 0.027	0.911AspTrp: 0.911 ± 0.012	1.552AspTyr: 1.552 ± 0.017	0.008AspXaa: 0.008 ± 0.001
Glu	5.319GluAla: 5.319 ± 0.038	0.634GluCys: 0.634 ± 0.011	4.051GluAsp: 4.051 ± 0.031	4.87GluGlu: 4.87 ± 0.045	1.969GluPhe: 1.969 ± 0.019	3.411GluGly: 3.411 ± 0.027	1.346GluHis: 1.346 ± 0.013	2.825GluIle: 2.825 ± 0.023	3.486GluLys: 3.486 ± 0.03	5.15GluLeu: 5.15 ± 0.036	1.487GluMet: 1.487 ± 0.015	2.205GluAsn: 2.205 ± 0.019	2.732GluPro: 2.732 ± 0.036	2.459GluGln: 2.459 ± 0.024	3.641GluArg: 3.641 ± 0.033	4.203GluSer: 4.203 ± 0.029	3.406GluThr: 3.406 ± 0.023	3.394GluVal: 3.394 ± 0.028	0.874GluTrp: 0.874 ± 0.012	1.638GluTyr: 1.638 ± 0.017	0.009GluXaa: 0.009 ± 0.001
Phe	3.112PheAla: 3.112 ± 0.026	0.58PheCys: 0.58 ± 0.011	2.342PheAsp: 2.342 ± 0.021	2.095PheGlu: 2.095 ± 0.02	1.642PhePhe: 1.642 ± 0.021	2.963PheGly: 2.963 ± 0.026	0.9PheHis: 0.9 ± 0.011	1.865PheIle: 1.865 ± 0.019	1.606PheLys: 1.606 ± 0.02	3.413PheLeu: 3.413 ± 0.028	0.84PheMet: 0.84 ± 0.013	1.496PheAsn: 1.496 ± 0.015	1.876PhePro: 1.876 ± 0.017	1.399PheGln: 1.399 ± 0.015	1.889PheArg: 1.889 ± 0.018	2.856PheSer: 2.856 ± 0.021	2.212PheThr: 2.212 ± 0.02	2.469PheVal: 2.469 ± 0.021	0.687PheTrp: 0.687 ± 0.011	1.101PheTyr: 1.101 ± 0.016	0.004PheXaa: 0.004 ± 0.001
Gly	5.412GlyAla: 5.412 ± 0.036	0.945GlyCys: 0.945 ± 0.013	3.808GlyAsp: 3.808 ± 0.03	3.598GlyGlu: 3.598 ± 0.028	2.802GlyPhe: 2.802 ± 0.026	5.875GlyGly: 5.875 ± 0.056	1.808GlyHis: 1.808 ± 0.02	3.686GlyIle: 3.686 ± 0.029	3.646GlyLys: 3.646 ± 0.028	6.113GlyLeu: 6.113 ± 0.042	1.701GlyMet: 1.701 ± 0.021	2.804GlyAsn: 2.804 ± 0.029	3.288GlyPro: 3.288 ± 0.027	2.731GlyGln: 2.731 ± 0.023	4.1GlyArg: 4.1 ± 0.03	5.807GlySer: 5.807 ± 0.036	4.083GlyThr: 4.083 ± 0.031	4.427GlyVal: 4.427 ± 0.03	1.22GlyTrp: 1.22 ± 0.015	2.152GlyTyr: 2.152 ± 0.022	0.013GlyXaa: 0.013 ± 0.001
His	1.786HisAla: 1.786 ± 0.018	0.343HisCys: 0.343 ± 0.007	1.4HisAsp: 1.4 ± 0.016	1.314HisGlu: 1.314 ± 0.014	0.906HisPhe: 0.906 ± 0.012	1.877HisGly: 1.877 ± 0.021	0.858HisHis: 0.858 ± 0.015	1.268HisIle: 1.268 ± 0.014	0.978HisLys: 0.978 ± 0.013	2.187HisLeu: 2.187 ± 0.021	0.522HisMet: 0.522 ± 0.01	0.879HisAsn: 0.879 ± 0.011	1.552HisPro: 1.552 ± 0.016	1.031HisGln: 1.031 ± 0.015	1.476HisArg: 1.476 ± 0.017	1.774HisSer: 1.774 ± 0.019	1.236HisThr: 1.236 ± 0.015	1.482HisVal: 1.482 ± 0.018	0.357HisTrp: 0.357 ± 0.008	0.652HisTyr: 0.652 ± 0.011	0.005HisXaa: 0.005 ± 0.001
Ile	4.303IleAla: 4.303 ± 0.032	0.798IleCys: 0.798 ± 0.013	2.887IleAsp: 2.887 ± 0.022	2.731IleGlu: 2.731 ± 0.022	1.998IlePhe: 1.998 ± 0.021	3.347IleGly: 3.347 ± 0.028	1.204IleHis: 1.204 ± 0.014	2.569IleIle: 2.569 ± 0.024	2.262IleLys: 2.262 ± 0.02	4.611IleLeu: 4.611 ± 0.032	1.085IleMet: 1.085 ± 0.015	1.848IleAsn: 1.848 ± 0.02	2.967IlePro: 2.967 ± 0.022	1.944IleGln: 1.944 ± 0.02	2.826IleArg: 2.826 ± 0.021	3.832IleSer: 3.832 ± 0.028	2.913IleThr: 2.913 ± 0.024	3.21IleVal: 3.21 ± 0.025	0.777IleTrp: 0.777 ± 0.013	1.375IleTyr: 1.375 ± 0.014	0.006IleXaa: 0.006 ± 0.001
Lys	4.386LysAla: 4.386 ± 0.032	0.553LysCys: 0.553 ± 0.012	3.009LysAsp: 3.009 ± 0.024	3.183LysGlu: 3.183 ± 0.031	1.609LysPhe: 1.609 ± 0.019	3.099LysGly: 3.099 ± 0.026	1.174LysHis: 1.174 ± 0.015	2.257LysIle: 2.257 ± 0.022	3.288LysLys: 3.288 ± 0.037	4.323LysLeu: 4.323 ± 0.03	1.099LysMet: 1.099 ± 0.014	1.814LysAsn: 1.814 ± 0.017	2.77LysPro: 2.77 ± 0.026	1.932LysGln: 1.932 ± 0.02	3.283LysArg: 3.283 ± 0.029	3.706LysSer: 3.706 ± 0.029	2.981LysThr: 2.981 ± 0.025	2.898LysVal: 2.898 ± 0.022	0.736LysTrp: 0.736 ± 0.011	1.445LysTyr: 1.445 ± 0.018	0.006LysXaa: 0.006 ± 0.001
Leu	7.987LeuAla: 7.987 ± 0.04	1.256LeuCys: 1.256 ± 0.014	5.281LeuAsp: 5.281 ± 0.036	5.251LeuGlu: 5.251 ± 0.037	3.28LeuPhe: 3.28 ± 0.027	6.017LeuGly: 6.017 ± 0.039	2.223LeuHis: 2.223 ± 0.024	3.946LeuIle: 3.946 ± 0.031	4.14LeuLys: 4.14 ± 0.03	8.311LeuLeu: 8.311 ± 0.054	1.836LeuMet: 1.836 ± 0.02	3.168LeuAsn: 3.168 ± 0.026	5.304LeuPro: 5.304 ± 0.033	3.843LeuGln: 3.843 ± 0.029	5.615LeuArg: 5.615 ± 0.033	7.083LeuSer: 7.083 ± 0.039	4.809LeuThr: 4.809 ± 0.032	5.531LeuVal: 5.531 ± 0.034	1.258LeuTrp: 1.258 ± 0.015	2.305LeuTyr: 2.305 ± 0.018	0.013LeuXaa: 0.013 ± 0.001
Met	2.384MetAla: 2.384 ± 0.02	0.263MetCys: 0.263 ± 0.007	1.346MetAsp: 1.346 ± 0.016	1.323MetGlu: 1.323 ± 0.016	0.784MetPhe: 0.784 ± 0.013	1.59MetGly: 1.59 ± 0.018	0.49MetHis: 0.49 ± 0.01	1.004MetIle: 1.004 ± 0.014	1.096MetLys: 1.096 ± 0.013	1.94MetLeu: 1.94 ± 0.017	0.616MetMet: 0.616 ± 0.012	0.855MetAsn: 0.855 ± 0.012	1.336MetPro: 1.336 ± 0.018	0.899MetGln: 0.899 ± 0.015	1.303MetArg: 1.303 ± 0.016	1.9MetSer: 1.9 ± 0.017	1.37MetThr: 1.37 ± 0.015	1.375MetVal: 1.375 ± 0.016	0.289MetTrp: 0.289 ± 0.008	0.58MetTyr: 0.58 ± 0.01	0.004MetXaa: 0.004 ± 0.001
Asn	3.164AsnAla: 3.164 ± 0.025	0.504AsnCys: 0.504 ± 0.011	2.072AsnAsp: 2.072 ± 0.019	2.034AsnGlu: 2.034 ± 0.019	1.445AsnPhe: 1.445 ± 0.017	3.24AsnGly: 3.24 ± 0.032	0.882AsnHis: 0.882 ± 0.012	2.116AsnIle: 2.116 ± 0.02	1.714AsnLys: 1.714 ± 0.019	3.331AsnLeu: 3.331 ± 0.024	0.922AsnMet: 0.922 ± 0.011	1.573AsnAsn: 1.573 ± 0.018	2.35AsnPro: 2.35 ± 0.021	1.356AsnGln: 1.356 ± 0.018	1.955AsnArg: 1.955 ± 0.019	2.839AsnSer: 2.839 ± 0.024	2.267AsnThr: 2.267 ± 0.024	2.425AsnVal: 2.425 ± 0.022	0.614AsnTrp: 0.614 ± 0.01	1.046AsnTyr: 1.046 ± 0.014	0.005AsnXaa: 0.005 ± 0.001
Pro	4.859ProAla: 4.859 ± 0.04	0.551ProCys: 0.551 ± 0.009	3.213ProAsp: 3.213 ± 0.024	3.59ProGlu: 3.59 ± 0.025	2.0ProPhe: 2.0 ± 0.022	3.985ProGly: 3.985 ± 0.032	1.257ProHis: 1.257 ± 0.017	2.472ProIle: 2.472 ± 0.021	2.691ProLys: 2.691 ± 0.022	4.514ProLeu: 4.514 ± 0.029	1.107ProMet: 1.107 ± 0.014	2.251ProAsn: 2.251 ± 0.023	4.724ProPro: 4.724 ± 0.055	2.401ProGln: 2.401 ± 0.028	3.181ProArg: 3.181 ± 0.028	5.522ProSer: 5.522 ± 0.04	3.814ProThr: 3.814 ± 0.033	3.553ProVal: 3.553 ± 0.028	0.769ProTrp: 0.769 ± 0.012	1.42ProTyr: 1.42 ± 0.018	0.011ProXaa: 0.011 ± 0.002
Gln	3.425GlnAla: 3.425 ± 0.028	0.455GlnCys: 0.455 ± 0.01	2.242GlnAsp: 2.242 ± 0.02	2.272GlnGlu: 2.272 ± 0.024	1.348GlnPhe: 1.348 ± 0.016	2.51GlnGly: 2.51 ± 0.02	1.12GlnHis: 1.12 ± 0.015	1.914GlnIle: 1.914 ± 0.018	1.965GlnLys: 1.965 ± 0.022	3.557GlnLeu: 3.557 ± 0.029	0.929GlnMet: 0.929 ± 0.014	1.598GlnAsn: 1.598 ± 0.02	2.552GlnPro: 2.552 ± 0.029	2.417GlnGln: 2.417 ± 0.036	2.559GlnArg: 2.559 ± 0.022	3.125GlnSer: 3.125 ± 0.029	2.382GlnThr: 2.382 ± 0.022	2.28GlnVal: 2.28 ± 0.021	0.576GlnTrp: 0.576 ± 0.01	1.159GlnTyr: 1.159 ± 0.016	0.006GlnXaa: 0.006 ± 0.001
Arg	4.412ArgAla: 4.412 ± 0.031	0.7ArgCys: 0.7 ± 0.012	3.46ArgAsp: 3.46 ± 0.029	3.557ArgGlu: 3.557 ± 0.03	2.058ArgPhe: 2.058 ± 0.018	3.662ArgGly: 3.662 ± 0.029	1.588ArgHis: 1.588 ± 0.019	2.848ArgIle: 2.848 ± 0.022	3.262ArgLys: 3.262 ± 0.03	5.364ArgLeu: 5.364 ± 0.034	1.3ArgMet: 1.3 ± 0.014	2.259ArgAsn: 2.259 ± 0.02	3.318ArgPro: 3.318 ± 0.031	2.649ArgGln: 2.649 ± 0.023	4.928ArgArg: 4.928 ± 0.046	4.465ArgSer: 4.465 ± 0.035	3.155ArgThr: 3.155 ± 0.026	3.301ArgVal: 3.301 ± 0.025	0.924ArgTrp: 0.924 ± 0.012	1.626ArgTyr: 1.626 ± 0.019	0.013ArgXaa: 0.013 ± 0.001
Ser	6.424SerAla: 6.424 ± 0.037	0.914SerCys: 0.914 ± 0.014	4.185SerAsp: 4.185 ± 0.031	3.995SerGlu: 3.995 ± 0.03	2.994SerPhe: 2.994 ± 0.025	5.615SerGly: 5.615 ± 0.035	1.946SerHis: 1.946 ± 0.021	4.017SerIle: 4.017 ± 0.03	3.853SerLys: 3.853 ± 0.031	6.983SerLeu: 6.983 ± 0.037	1.779SerMet: 1.779 ± 0.018	3.075SerAsn: 3.075 ± 0.025	5.153SerPro: 5.153 ± 0.049	3.371SerGln: 3.371 ± 0.026	4.826SerArg: 4.826 ± 0.034	8.114SerSer: 8.114 ± 0.063	5.415SerThr: 5.415 ± 0.037	4.535SerVal: 4.535 ± 0.029	1.196SerTrp: 1.196 ± 0.015	2.027SerTyr: 2.027 ± 0.018	0.014SerXaa: 0.014 ± 0.002
Thr	5.247ThrAla: 5.247 ± 0.032	0.768ThrCys: 0.768 ± 0.014	2.941ThrAsp: 2.941 ± 0.024	3.119ThrGlu: 3.119 ± 0.026	2.233ThrPhe: 2.233 ± 0.022	4.283ThrGly: 4.283 ± 0.03	1.271ThrHis: 1.271 ± 0.016	3.157ThrIle: 3.157 ± 0.027	2.834ThrLys: 2.834 ± 0.024	5.174ThrLeu: 5.174 ± 0.033	1.265ThrMet: 1.265 ± 0.016	2.235ThrAsn: 2.235 ± 0.021	4.135ThrPro: 4.135 ± 0.028	2.144ThrGln: 2.144 ± 0.022	3.056ThrArg: 3.056 ± 0.026	5.286ThrSer: 5.286 ± 0.036	4.355ThrThr: 4.355 ± 0.043	3.784ThrVal: 3.784 ± 0.031	0.892ThrTrp: 0.892 ± 0.013	1.598ThrTyr: 1.598 ± 0.017	0.008ThrXaa: 0.008 ± 0.001
Val	5.445ValAla: 5.445 ± 0.036	0.865ValCys: 0.865 ± 0.014	3.893ValAsp: 3.893 ± 0.03	3.771ValGlu: 3.771 ± 0.027	2.498ValPhe: 2.498 ± 0.025	4.151ValGly: 4.151 ± 0.029	1.397ValHis: 1.397 ± 0.016	2.951ValIle: 2.951 ± 0.026	3.005ValLys: 3.005 ± 0.025	5.632ValLeu: 5.632 ± 0.04	1.381ValMet: 1.381 ± 0.016	2.35ValAsn: 2.35 ± 0.022	3.589ValPro: 3.589 ± 0.027	2.415ValGln: 2.415 ± 0.021	3.35ValArg: 3.35 ± 0.026	4.648ValSer: 4.648 ± 0.03	3.658ValThr: 3.658 ± 0.029	4.465ValVal: 4.465 ± 0.035	0.877ValTrp: 0.877 ± 0.012	1.706ValTyr: 1.706 ± 0.017	0.008ValXaa: 0.008 ± 0.001
Trp	1.218TrpAla: 1.218 ± 0.014	0.208TrpCys: 0.208 ± 0.006	0.968TrpAsp: 0.968 ± 0.014	0.847TrpGlu: 0.847 ± 0.013	0.566TrpPhe: 0.566 ± 0.008	0.989TrpGly: 0.989 ± 0.015	0.379TrpHis: 0.379 ± 0.008	0.792TrpIle: 0.792 ± 0.013	0.836TrpLys: 0.836 ± 0.011	1.376TrpLeu: 1.376 ± 0.018	0.398TrpMet: 0.398 ± 0.008	0.649TrpAsn: 0.649 ± 0.012	0.646TrpPro: 0.646 ± 0.011	0.611TrpGln: 0.611 ± 0.009	0.95TrpArg: 0.95 ± 0.013	1.08TrpSer: 1.08 ± 0.015	0.966TrpThr: 0.966 ± 0.013	0.924TrpVal: 0.924 ± 0.012	0.311TrpTrp: 0.311 ± 0.008	0.451TrpTyr: 0.451 ± 0.01	0.002TrpXaa: 0.002 ± 0.001
Tyr	2.146TyrAla: 2.146 ± 0.021	0.418TyrCys: 0.418 ± 0.009	1.677TyrAsp: 1.677 ± 0.02	1.471TyrGlu: 1.471 ± 0.016	1.215TyrPhe: 1.215 ± 0.016	2.111TyrGly: 2.111 ± 0.023	0.726TyrHis: 0.726 ± 0.011	1.398TyrIle: 1.398 ± 0.017	1.169TyrLys: 1.169 ± 0.015	2.584TyrLeu: 2.584 ± 0.023	0.646TyrMet: 0.646 ± 0.01	1.131TyrAsn: 1.131 ± 0.015	1.434TyrPro: 1.434 ± 0.016	1.053TyrGln: 1.053 ± 0.014	1.554TyrArg: 1.554 ± 0.016	1.967TyrSer: 1.967 ± 0.019	1.566TyrThr: 1.566 ± 0.018	1.629TyrVal: 1.629 ± 0.017	0.468TyrTrp: 0.468 ± 0.009	0.93TyrTyr: 0.93 ± 0.014	0.003TyrXaa: 0.003 ± 0.001
Xaa	0.018XaaAla: 0.018 ± 0.002	0.003XaaCys: 0.003 ± 0.001	0.006XaaAsp: 0.006 ± 0.001	0.007XaaGlu: 0.007 ± 0.001	0.005XaaPhe: 0.005 ± 0.001	0.014XaaGly: 0.014 ± 0.001	0.003XaaHis: 0.003 ± 0.001	0.005XaaIle: 0.005 ± 0.001	0.008XaaLys: 0.008 ± 0.001	0.014XaaLeu: 0.014 ± 0.002	0.005XaaMet: 0.005 ± 0.001	0.006XaaAsn: 0.006 ± 0.001	0.012XaaPro: 0.012 ± 0.001	0.006XaaGln: 0.006 ± 0.001	0.012XaaArg: 0.012 ± 0.001	0.013XaaSer: 0.013 ± 0.001	0.01XaaThr: 0.01 ± 0.001	0.008XaaVal: 0.008 ± 0.001	0.004XaaTrp: 0.004 ± 0.001	0.004XaaTyr: 0.004 ± 0.001	2.212XaaXaa: 2.212 ± 0.095

Statistics based on 11960 proteins (5937693 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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