Amino acid dipepetide frequency for Galactobacter valiniphilus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
23.763AlaAla: 23.763 ± 0.265
0.861AlaCys: 0.861 ± 0.035
7.09AlaAsp: 7.09 ± 0.095
8.836AlaGlu: 8.836 ± 0.132
3.715AlaPhe: 3.715 ± 0.071
13.622AlaGly: 13.622 ± 0.143
2.536AlaHis: 2.536 ± 0.056
4.783AlaIle: 4.783 ± 0.084
3.732AlaLys: 3.732 ± 0.082
15.539AlaLeu: 15.539 ± 0.169
2.866AlaMet: 2.866 ± 0.053
2.34AlaAsn: 2.34 ± 0.057
7.896AlaPro: 7.896 ± 0.13
4.651AlaGln: 4.651 ± 0.082
9.16AlaArg: 9.16 ± 0.125
8.126AlaSer: 8.126 ± 0.094
7.295AlaThr: 7.295 ± 0.107
11.453AlaVal: 11.453 ± 0.132
2.344AlaTrp: 2.344 ± 0.061
2.278AlaTyr: 2.278 ± 0.053
0.0AlaXaa: 0.0 ± 0.0
Cys
0.773CysAla: 0.773 ± 0.027
0.051CysCys: 0.051 ± 0.006
0.274CysAsp: 0.274 ± 0.018
0.284CysGlu: 0.284 ± 0.016
0.203CysPhe: 0.203 ± 0.014
0.613CysGly: 0.613 ± 0.022
0.115CysHis: 0.115 ± 0.012
0.198CysIle: 0.198 ± 0.016
0.087CysLys: 0.087 ± 0.009
0.553CysLeu: 0.553 ± 0.022
0.074CysMet: 0.074 ± 0.008
0.109CysAsn: 0.109 ± 0.012
0.325CysPro: 0.325 ± 0.017
0.139CysGln: 0.139 ± 0.013
0.342CysArg: 0.342 ± 0.018
0.379CysSer: 0.379 ± 0.022
0.366CysThr: 0.366 ± 0.019
0.462CysVal: 0.462 ± 0.022
0.085CysTrp: 0.085 ± 0.01
0.086CysTyr: 0.086 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
8.286AspAla: 8.286 ± 0.11
0.218AspCys: 0.218 ± 0.014
2.991AspAsp: 2.991 ± 0.074
3.869AspGlu: 3.869 ± 0.072
1.586AspPhe: 1.586 ± 0.044
5.444AspGly: 5.444 ± 0.088
1.131AspHis: 1.131 ± 0.037
1.743AspIle: 1.743 ± 0.045
1.24AspLys: 1.24 ± 0.044
5.224AspLeu: 5.224 ± 0.085
0.815AspMet: 0.815 ± 0.032
0.788AspAsn: 0.788 ± 0.034
4.051AspPro: 4.051 ± 0.07
1.225AspGln: 1.225 ± 0.038
3.493AspArg: 3.493 ± 0.066
2.253AspSer: 2.253 ± 0.05
2.57AspThr: 2.57 ± 0.057
4.858AspVal: 4.858 ± 0.083
0.736AspTrp: 0.736 ± 0.028
1.144AspTyr: 1.144 ± 0.043
0.0AspXaa: 0.0 ± 0.0
Glu
9.444GluAla: 9.444 ± 0.122
0.283GluCys: 0.283 ± 0.018
3.468GluAsp: 3.468 ± 0.07
3.882GluGlu: 3.882 ± 0.073
1.65GluPhe: 1.65 ± 0.048
4.898GluGly: 4.898 ± 0.081
1.701GluHis: 1.701 ± 0.044
2.268GluIle: 2.268 ± 0.051
1.465GluLys: 1.465 ± 0.044
7.269GluLeu: 7.269 ± 0.095
0.868GluMet: 0.868 ± 0.028
1.258GluAsn: 1.258 ± 0.037
3.181GluPro: 3.181 ± 0.075
2.246GluGln: 2.246 ± 0.046
5.443GluArg: 5.443 ± 0.095
2.769GluSer: 2.769 ± 0.053
2.7GluThr: 2.7 ± 0.052
4.585GluVal: 4.585 ± 0.082
0.851GluTrp: 0.851 ± 0.032
1.113GluTyr: 1.113 ± 0.039
0.0GluXaa: 0.0 ± 0.0
Phe
3.744PheAla: 3.744 ± 0.061
0.214PheCys: 0.214 ± 0.015
1.969PheAsp: 1.969 ± 0.048
1.779PheGlu: 1.779 ± 0.046
1.027PhePhe: 1.027 ± 0.038
3.225PheGly: 3.225 ± 0.063
0.541PheHis: 0.541 ± 0.022
1.022PheIle: 1.022 ± 0.04
0.743PheLys: 0.743 ± 0.029
2.762PheLeu: 2.762 ± 0.057
0.542PheMet: 0.542 ± 0.024
0.764PheAsn: 0.764 ± 0.028
1.383PhePro: 1.383 ± 0.037
0.699PheGln: 0.699 ± 0.026
1.497PheArg: 1.497 ± 0.04
1.873PheSer: 1.873 ± 0.044
2.014PheThr: 2.014 ± 0.051
2.514PheVal: 2.514 ± 0.063
0.477PheTrp: 0.477 ± 0.022
0.569PheTyr: 0.569 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
12.428GlyAla: 12.428 ± 0.159
0.525GlyCys: 0.525 ± 0.022
4.358GlyAsp: 4.358 ± 0.071
5.785GlyGlu: 5.785 ± 0.079
3.238GlyPhe: 3.238 ± 0.066
8.275GlyGly: 8.275 ± 0.11
2.02GlyHis: 2.02 ± 0.044
3.771GlyIle: 3.771 ± 0.071
2.701GlyLys: 2.701 ± 0.07
9.88GlyLeu: 9.88 ± 0.116
1.863GlyMet: 1.863 ± 0.041
1.914GlyAsn: 1.914 ± 0.046
4.185GlyPro: 4.185 ± 0.066
2.877GlyGln: 2.877 ± 0.054
6.447GlyArg: 6.447 ± 0.095
5.627GlySer: 5.627 ± 0.086
5.944GlyThr: 5.944 ± 0.094
7.936GlyVal: 7.936 ± 0.097
1.826GlyTrp: 1.826 ± 0.047
2.038GlyTyr: 2.038 ± 0.042
0.0GlyXaa: 0.0 ± 0.0
His
2.656HisAla: 2.656 ± 0.056
0.119HisCys: 0.119 ± 0.01
1.122HisAsp: 1.122 ± 0.038
1.267HisGlu: 1.267 ± 0.036
0.555HisPhe: 0.555 ± 0.025
2.042HisGly: 2.042 ± 0.05
0.627HisHis: 0.627 ± 0.028
0.588HisIle: 0.588 ± 0.024
0.344HisLys: 0.344 ± 0.019
2.136HisLeu: 2.136 ± 0.048
0.311HisMet: 0.311 ± 0.018
0.303HisAsn: 0.303 ± 0.017
1.548HisPro: 1.548 ± 0.041
0.569HisGln: 0.569 ± 0.023
1.652HisArg: 1.652 ± 0.047
0.97HisSer: 0.97 ± 0.028
1.061HisThr: 1.061 ± 0.037
1.675HisVal: 1.675 ± 0.05
0.306HisTrp: 0.306 ± 0.017
0.403HisTyr: 0.403 ± 0.023
0.0HisXaa: 0.0 ± 0.0
Ile
5.229IleAla: 5.229 ± 0.08
0.215IleCys: 0.215 ± 0.016
2.56IleAsp: 2.56 ± 0.054
2.406IleGlu: 2.406 ± 0.064
0.987IlePhe: 0.987 ± 0.039
3.709IleGly: 3.709 ± 0.072
0.648IleHis: 0.648 ± 0.031
1.514IleIle: 1.514 ± 0.047
1.074IleLys: 1.074 ± 0.033
3.19IleLeu: 3.19 ± 0.062
0.729IleMet: 0.729 ± 0.031
0.936IleAsn: 0.936 ± 0.029
1.96IlePro: 1.96 ± 0.045
0.911IleGln: 0.911 ± 0.029
1.862IleArg: 1.862 ± 0.045
2.109IleSer: 2.109 ± 0.049
2.463IleThr: 2.463 ± 0.056
3.606IleVal: 3.606 ± 0.071
0.364IleTrp: 0.364 ± 0.02
0.627IleTyr: 0.627 ± 0.024
0.0IleXaa: 0.0 ± 0.0
Lys
3.567LysAla: 3.567 ± 0.084
0.094LysCys: 0.094 ± 0.011
1.646LysAsp: 1.646 ± 0.047
1.302LysGlu: 1.302 ± 0.043
0.539LysPhe: 0.539 ± 0.024
2.016LysGly: 2.016 ± 0.053
0.589LysHis: 0.589 ± 0.024
1.095LysIle: 1.095 ± 0.043
1.056LysLys: 1.056 ± 0.048
2.4LysLeu: 2.4 ± 0.06
0.504LysMet: 0.504 ± 0.024
0.777LysAsn: 0.777 ± 0.031
1.387LysPro: 1.387 ± 0.044
0.858LysGln: 0.858 ± 0.03
1.767LysArg: 1.767 ± 0.046
1.324LysSer: 1.324 ± 0.049
1.503LysThr: 1.503 ± 0.054
2.242LysVal: 2.242 ± 0.064
0.265LysTrp: 0.265 ± 0.017
0.529LysTyr: 0.529 ± 0.029
0.0LysXaa: 0.0 ± 0.0
Leu
15.601LeuAla: 15.601 ± 0.158
0.597LeuCys: 0.597 ± 0.027
5.885LeuAsp: 5.885 ± 0.088
6.016LeuGlu: 6.016 ± 0.093
2.827LeuPhe: 2.827 ± 0.061
10.299LeuGly: 10.299 ± 0.125
1.914LeuHis: 1.914 ± 0.05
3.947LeuIle: 3.947 ± 0.075
2.585LeuLys: 2.585 ± 0.058
10.564LeuLeu: 10.564 ± 0.152
1.821LeuMet: 1.821 ± 0.046
2.09LeuAsn: 2.09 ± 0.05
5.959LeuPro: 5.959 ± 0.092
2.473LeuGln: 2.473 ± 0.051
7.693LeuArg: 7.693 ± 0.092
6.438LeuSer: 6.438 ± 0.082
5.919LeuThr: 5.919 ± 0.089
9.09LeuVal: 9.09 ± 0.119
1.311LeuTrp: 1.311 ± 0.043
1.597LeuTyr: 1.597 ± 0.037
0.0LeuXaa: 0.0 ± 0.0
Met
2.221MetAla: 2.221 ± 0.044
0.082MetCys: 0.082 ± 0.009
0.943MetAsp: 0.943 ± 0.029
0.808MetGlu: 0.808 ± 0.027
0.527MetPhe: 0.527 ± 0.022
1.508MetGly: 1.508 ± 0.037
0.323MetHis: 0.323 ± 0.017
0.824MetIle: 0.824 ± 0.031
0.487MetLys: 0.487 ± 0.025
1.701MetLeu: 1.701 ± 0.042
0.315MetMet: 0.315 ± 0.018
0.576MetAsn: 0.576 ± 0.027
1.056MetPro: 1.056 ± 0.036
0.51MetGln: 0.51 ± 0.026
1.317MetArg: 1.317 ± 0.034
1.586MetSer: 1.586 ± 0.038
1.279MetThr: 1.279 ± 0.038
1.416MetVal: 1.416 ± 0.04
0.204MetTrp: 0.204 ± 0.013
0.267MetTyr: 0.267 ± 0.016
0.0MetXaa: 0.0 ± 0.0
Asn
2.737AsnAla: 2.737 ± 0.06
0.115AsnCys: 0.115 ± 0.012
1.085AsnAsp: 1.085 ± 0.034
1.115AsnGlu: 1.115 ± 0.042
0.618AsnPhe: 0.618 ± 0.023
1.944AsnGly: 1.944 ± 0.048
0.417AsnHis: 0.417 ± 0.02
0.802AsnIle: 0.802 ± 0.032
0.578AsnLys: 0.578 ± 0.028
1.93AsnLeu: 1.93 ± 0.049
0.342AsnMet: 0.342 ± 0.019
0.539AsnAsn: 0.539 ± 0.025
1.524AsnPro: 1.524 ± 0.038
0.642AsnGln: 0.642 ± 0.026
1.166AsnArg: 1.166 ± 0.035
0.997AsnSer: 0.997 ± 0.033
1.198AsnThr: 1.198 ± 0.041
1.721AsnVal: 1.721 ± 0.048
0.288AsnTrp: 0.288 ± 0.018
0.482AsnTyr: 0.482 ± 0.024
0.0AsnXaa: 0.0 ± 0.0
Pro
8.649ProAla: 8.649 ± 0.143
0.22ProCys: 0.22 ± 0.017
3.147ProAsp: 3.147 ± 0.056
4.558ProGlu: 4.558 ± 0.078
1.599ProPhe: 1.599 ± 0.043
6.015ProGly: 6.015 ± 0.084
1.126ProHis: 1.126 ± 0.034
1.517ProIle: 1.517 ± 0.044
1.162ProLys: 1.162 ± 0.038
5.153ProLeu: 5.153 ± 0.073
0.789ProMet: 0.789 ± 0.03
0.971ProAsn: 0.971 ± 0.034
2.189ProPro: 2.189 ± 0.06
1.681ProGln: 1.681 ± 0.048
3.621ProArg: 3.621 ± 0.079
3.544ProSer: 3.544 ± 0.068
3.234ProThr: 3.234 ± 0.073
4.795ProVal: 4.795 ± 0.071
0.963ProTrp: 0.963 ± 0.034
0.91ProTyr: 0.91 ± 0.03
0.0ProXaa: 0.0 ± 0.0
Gln
4.46GlnAla: 4.46 ± 0.077
0.155GlnCys: 0.155 ± 0.011
1.529GlnAsp: 1.529 ± 0.039
1.734GlnGlu: 1.734 ± 0.042
0.739GlnPhe: 0.739 ± 0.027
2.502GlnGly: 2.502 ± 0.049
0.656GlnHis: 0.656 ± 0.027
1.266GlnIle: 1.266 ± 0.036
0.723GlnLys: 0.723 ± 0.035
3.323GlnLeu: 3.323 ± 0.061
0.495GlnMet: 0.495 ± 0.026
0.6GlnAsn: 0.6 ± 0.024
1.606GlnPro: 1.606 ± 0.043
1.174GlnGln: 1.174 ± 0.041
2.567GlnArg: 2.567 ± 0.049
1.337GlnSer: 1.337 ± 0.038
1.251GlnThr: 1.251 ± 0.037
2.315GlnVal: 2.315 ± 0.049
0.45GlnTrp: 0.45 ± 0.02
0.565GlnTyr: 0.565 ± 0.032
0.0GlnXaa: 0.0 ± 0.0
Arg
8.853ArgAla: 8.853 ± 0.134
0.395ArgCys: 0.395 ± 0.021
3.335ArgAsp: 3.335 ± 0.062
4.75ArgGlu: 4.75 ± 0.067
2.241ArgPhe: 2.241 ± 0.052
5.754ArgGly: 5.754 ± 0.081
1.582ArgHis: 1.582 ± 0.044
2.669ArgIle: 2.669 ± 0.057
1.571ArgLys: 1.571 ± 0.049
7.608ArgLeu: 7.608 ± 0.112
1.383ArgMet: 1.383 ± 0.041
1.264ArgAsn: 1.264 ± 0.04
3.825ArgPro: 3.825 ± 0.065
1.995ArgGln: 1.995 ± 0.048
6.356ArgArg: 6.356 ± 0.125
3.942ArgSer: 3.942 ± 0.066
3.769ArgThr: 3.769 ± 0.068
5.733ArgVal: 5.733 ± 0.084
1.275ArgTrp: 1.275 ± 0.042
1.358ArgTyr: 1.358 ± 0.039
0.0ArgXaa: 0.0 ± 0.0
Ser
7.735SerAla: 7.735 ± 0.104
0.294SerCys: 0.294 ± 0.017
2.651SerAsp: 2.651 ± 0.059
3.103SerGlu: 3.103 ± 0.064
1.821SerPhe: 1.821 ± 0.039
6.027SerGly: 6.027 ± 0.074
1.06SerHis: 1.06 ± 0.034
2.084SerIle: 2.084 ± 0.047
1.47SerLys: 1.47 ± 0.05
5.893SerLeu: 5.893 ± 0.086
1.186SerMet: 1.186 ± 0.038
1.191SerAsn: 1.191 ± 0.031
3.169SerPro: 3.169 ± 0.054
1.624SerGln: 1.624 ± 0.042
3.565SerArg: 3.565 ± 0.06
3.712SerSer: 3.712 ± 0.087
3.807SerThr: 3.807 ± 0.067
4.866SerVal: 4.866 ± 0.078
0.946SerTrp: 0.946 ± 0.032
1.188SerTyr: 1.188 ± 0.035
0.0SerXaa: 0.0 ± 0.0
Thr
7.281ThrAla: 7.281 ± 0.103
0.291ThrCys: 0.291 ± 0.019
2.771ThrAsp: 2.771 ± 0.064
3.131ThrGlu: 3.131 ± 0.061
1.694ThrPhe: 1.694 ± 0.043
5.497ThrGly: 5.497 ± 0.096
1.088ThrHis: 1.088 ± 0.035
2.145ThrIle: 2.145 ± 0.051
1.433ThrLys: 1.433 ± 0.044
6.084ThrLeu: 6.084 ± 0.088
0.899ThrMet: 0.899 ± 0.029
1.098ThrAsn: 1.098 ± 0.04
4.047ThrPro: 4.047 ± 0.064
1.757ThrGln: 1.757 ± 0.048
3.565ThrArg: 3.565 ± 0.071
3.328ThrSer: 3.328 ± 0.07
3.436ThrThr: 3.436 ± 0.063
5.276ThrVal: 5.276 ± 0.077
0.838ThrTrp: 0.838 ± 0.035
1.006ThrTyr: 1.006 ± 0.034
0.0ThrXaa: 0.0 ± 0.0
Val
11.304ValAla: 11.304 ± 0.126
0.552ValCys: 0.552 ± 0.025
4.934ValAsp: 4.934 ± 0.081
4.847ValGlu: 4.847 ± 0.086
2.583ValPhe: 2.583 ± 0.05
7.173ValGly: 7.173 ± 0.088
1.575ValHis: 1.575 ± 0.037
3.562ValIle: 3.562 ± 0.067
2.222ValLys: 2.222 ± 0.064
9.631ValLeu: 9.631 ± 0.115
1.559ValMet: 1.559 ± 0.044
1.869ValAsn: 1.869 ± 0.041
4.883ValPro: 4.883 ± 0.065
2.337ValGln: 2.337 ± 0.05
5.593ValArg: 5.593 ± 0.088
5.172ValSer: 5.172 ± 0.082
5.003ValThr: 5.003 ± 0.078
7.977ValVal: 7.977 ± 0.105
1.174ValTrp: 1.174 ± 0.038
1.398ValTyr: 1.398 ± 0.041
0.0ValXaa: 0.0 ± 0.0
Trp
1.841TrpAla: 1.841 ± 0.05
0.133TrpCys: 0.133 ± 0.011
0.862TrpAsp: 0.862 ± 0.032
0.796TrpGlu: 0.796 ± 0.03
0.588TrpPhe: 0.588 ± 0.028
1.321TrpGly: 1.321 ± 0.039
0.293TrpHis: 0.293 ± 0.017
0.761TrpIle: 0.761 ± 0.029
0.34TrpLys: 0.34 ± 0.021
1.799TrpLeu: 1.799 ± 0.048
0.356TrpMet: 0.356 ± 0.017
0.423TrpAsn: 0.423 ± 0.02
0.72TrpPro: 0.72 ± 0.032
0.499TrpGln: 0.499 ± 0.024
1.177TrpArg: 1.177 ± 0.038
0.782TrpSer: 0.782 ± 0.03
0.776TrpThr: 0.776 ± 0.029
1.291TrpVal: 1.291 ± 0.039
0.396TrpTrp: 0.396 ± 0.022
0.246TrpTyr: 0.246 ± 0.015
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.315TyrAla: 2.315 ± 0.053
0.106TyrCys: 0.106 ± 0.011
1.044TyrAsp: 1.044 ± 0.034
1.072TyrGlu: 1.072 ± 0.035
0.618TyrPhe: 0.618 ± 0.029
1.755TyrGly: 1.755 ± 0.04
0.312TyrHis: 0.312 ± 0.018
0.542TyrIle: 0.542 ± 0.025
0.446TyrLys: 0.446 ± 0.024
1.987TyrLeu: 1.987 ± 0.043
0.233TyrMet: 0.233 ± 0.015
0.429TyrAsn: 0.429 ± 0.021
0.949TyrPro: 0.949 ± 0.03
0.583TyrGln: 0.583 ± 0.025
1.377TyrArg: 1.377 ± 0.035
1.121TyrSer: 1.121 ± 0.037
1.076TyrThr: 1.076 ± 0.042
1.538TyrVal: 1.538 ± 0.052
0.3TyrTrp: 0.3 ± 0.019
0.407TyrTyr: 0.407 ± 0.021
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3019 proteins (969195 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski