Amino acid dipepetide frequency for Zoogloea ramigera

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.301AlaAla: 18.301 ± 0.187	1.4AlaCys: 1.4 ± 0.036	7.319AlaAsp: 7.319 ± 0.095	8.003AlaGlu: 8.003 ± 0.099	4.193AlaPhe: 4.193 ± 0.066	11.437AlaGly: 11.437 ± 0.121	2.636AlaHis: 2.636 ± 0.045	5.455AlaIle: 5.455 ± 0.067	3.424AlaLys: 3.424 ± 0.073	14.92AlaLeu: 14.92 ± 0.135	3.073AlaMet: 3.073 ± 0.058	2.861AlaAsn: 2.861 ± 0.052	6.452AlaPro: 6.452 ± 0.091	4.375AlaGln: 4.375 ± 0.068	10.071AlaArg: 10.071 ± 0.124	6.444AlaSer: 6.444 ± 0.085	5.645AlaThr: 5.645 ± 0.084	8.531AlaVal: 8.531 ± 0.103	1.853AlaTrp: 1.853 ± 0.038	2.484AlaTyr: 2.484 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.121CysAla: 1.121 ± 0.034	0.143CysCys: 0.143 ± 0.01	0.526CysAsp: 0.526 ± 0.021	0.531CysGlu: 0.531 ± 0.022	0.355CysPhe: 0.355 ± 0.015	1.028CysGly: 1.028 ± 0.029	0.33CysHis: 0.33 ± 0.019	0.406CysIle: 0.406 ± 0.019	0.228CysLys: 0.228 ± 0.014	0.947CysLeu: 0.947 ± 0.028	0.181CysMet: 0.181 ± 0.013	0.248CysAsn: 0.248 ± 0.014	0.578CysPro: 0.578 ± 0.023	0.28CysGln: 0.28 ± 0.016	0.716CysArg: 0.716 ± 0.025	0.496CysSer: 0.496 ± 0.02	0.452CysThr: 0.452 ± 0.02	0.684CysVal: 0.684 ± 0.024	0.133CysTrp: 0.133 ± 0.01	0.206CysTyr: 0.206 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.29AspAla: 7.29 ± 0.083	0.54AspCys: 0.54 ± 0.022	3.17AspAsp: 3.17 ± 0.062	3.771AspGlu: 3.771 ± 0.067	2.359AspPhe: 2.359 ± 0.056	4.997AspGly: 4.997 ± 0.065	1.089AspHis: 1.089 ± 0.033	2.681AspIle: 2.681 ± 0.044	1.951AspLys: 1.951 ± 0.047	5.319AspLeu: 5.319 ± 0.073	1.108AspMet: 1.108 ± 0.028	1.321AspAsn: 1.321 ± 0.035	3.131AspPro: 3.131 ± 0.049	1.577AspGln: 1.577 ± 0.033	3.323AspArg: 3.323 ± 0.06	2.526AspSer: 2.526 ± 0.042	2.782AspThr: 2.782 ± 0.059	3.849AspVal: 3.849 ± 0.056	0.951AspTrp: 0.951 ± 0.033	1.493AspTyr: 1.493 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	8.48GluAla: 8.48 ± 0.112	0.433GluCys: 0.433 ± 0.019	2.433GluAsp: 2.433 ± 0.048	2.748GluGlu: 2.748 ± 0.046	1.829GluPhe: 1.829 ± 0.038	4.212GluGly: 4.212 ± 0.069	1.414GluHis: 1.414 ± 0.036	3.122GluIle: 3.122 ± 0.05	2.141GluLys: 2.141 ± 0.048	6.502GluLeu: 6.502 ± 0.087	1.359GluMet: 1.359 ± 0.034	1.335GluAsn: 1.335 ± 0.033	2.693GluPro: 2.693 ± 0.05	2.448GluGln: 2.448 ± 0.055	4.933GluArg: 4.933 ± 0.075	2.645GluSer: 2.645 ± 0.048	2.887GluThr: 2.887 ± 0.05	4.267GluVal: 4.267 ± 0.072	0.814GluTrp: 0.814 ± 0.027	1.086GluTyr: 1.086 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.36PheAla: 4.36 ± 0.061	0.433PheCys: 0.433 ± 0.018	2.534PheAsp: 2.534 ± 0.05	2.359PheGlu: 2.359 ± 0.043	1.384PhePhe: 1.384 ± 0.035	3.33PheGly: 3.33 ± 0.061	0.773PheHis: 0.773 ± 0.027	1.61PheIle: 1.61 ± 0.034	1.115PheLys: 1.115 ± 0.032	3.18PheLeu: 3.18 ± 0.055	0.75PheMet: 0.75 ± 0.026	1.053PheAsn: 1.053 ± 0.028	1.507PhePro: 1.507 ± 0.035	1.042PheGln: 1.042 ± 0.026	2.247PheArg: 2.247 ± 0.043	2.159PheSer: 2.159 ± 0.044	1.807PheThr: 1.807 ± 0.048	2.748PheVal: 2.748 ± 0.049	0.471PheTrp: 0.471 ± 0.022	0.843PheTyr: 0.843 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	8.857GlyAla: 8.857 ± 0.109	0.963GlyCys: 0.963 ± 0.026	4.296GlyAsp: 4.296 ± 0.088	5.016GlyGlu: 5.016 ± 0.064	3.42GlyPhe: 3.42 ± 0.056	7.167GlyGly: 7.167 ± 0.117	1.988GlyHis: 1.988 ± 0.04	3.874GlyIle: 3.874 ± 0.058	3.454GlyLys: 3.454 ± 0.056	9.478GlyLeu: 9.478 ± 0.091	2.184GlyMet: 2.184 ± 0.04	2.203GlyAsn: 2.203 ± 0.064	3.067GlyPro: 3.067 ± 0.054	3.241GlyGln: 3.241 ± 0.058	6.303GlyArg: 6.303 ± 0.074	4.669GlySer: 4.669 ± 0.106	3.903GlyThr: 3.903 ± 0.104	6.44GlyVal: 6.44 ± 0.08	1.385GlyTrp: 1.385 ± 0.034	2.14GlyTyr: 2.14 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.588HisAla: 2.588 ± 0.049	0.268HisCys: 0.268 ± 0.014	1.285HisAsp: 1.285 ± 0.037	1.128HisGlu: 1.128 ± 0.028	0.979HisPhe: 0.979 ± 0.029	2.051HisGly: 2.051 ± 0.046	0.687HisHis: 0.687 ± 0.027	0.959HisIle: 0.959 ± 0.029	0.572HisLys: 0.572 ± 0.023	2.486HisLeu: 2.486 ± 0.049	0.414HisMet: 0.414 ± 0.02	0.508HisAsn: 0.508 ± 0.018	1.575HisPro: 1.575 ± 0.035	0.722HisGln: 0.722 ± 0.025	1.505HisArg: 1.505 ± 0.038	1.037HisSer: 1.037 ± 0.029	1.009HisThr: 1.009 ± 0.031	1.46HisVal: 1.46 ± 0.035	0.372HisTrp: 0.372 ± 0.018	0.627HisTyr: 0.627 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.951IleAla: 5.951 ± 0.077	0.4IleCys: 0.4 ± 0.02	3.057IleAsp: 3.057 ± 0.054	3.25IleGlu: 3.25 ± 0.063	1.387IlePhe: 1.387 ± 0.033	4.151IleGly: 4.151 ± 0.058	1.021IleHis: 1.021 ± 0.03	1.754IleIle: 1.754 ± 0.038	1.57IleLys: 1.57 ± 0.045	3.864IleLeu: 3.864 ± 0.059	0.702IleMet: 0.702 ± 0.025	1.465IleAsn: 1.465 ± 0.04	2.182IlePro: 2.182 ± 0.044	1.327IleGln: 1.327 ± 0.034	3.065IleArg: 3.065 ± 0.047	2.435IleSer: 2.435 ± 0.051	2.415IleThr: 2.415 ± 0.056	3.498IleVal: 3.498 ± 0.051	0.417IleTrp: 0.417 ± 0.017	0.96IleTyr: 0.96 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	4.226LysAla: 4.226 ± 0.079	0.186LysCys: 0.186 ± 0.013	1.659LysAsp: 1.659 ± 0.044	1.56LysGlu: 1.56 ± 0.045	0.931LysPhe: 0.931 ± 0.028	2.484LysGly: 2.484 ± 0.049	0.631LysHis: 0.631 ± 0.023	1.514LysIle: 1.514 ± 0.035	1.349LysLys: 1.349 ± 0.044	3.602LysLeu: 3.602 ± 0.054	0.755LysMet: 0.755 ± 0.024	0.957LysAsn: 0.957 ± 0.027	2.219LysPro: 2.219 ± 0.045	1.135LysGln: 1.135 ± 0.032	2.24LysArg: 2.24 ± 0.044	1.7LysSer: 1.7 ± 0.041	1.708LysThr: 1.708 ± 0.038	2.523LysVal: 2.523 ± 0.059	0.344LysTrp: 0.344 ± 0.019	0.658LysTyr: 0.658 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	16.322LeuAla: 16.322 ± 0.16	1.099LeuCys: 1.099 ± 0.033	6.445LeuAsp: 6.445 ± 0.083	6.083LeuGlu: 6.083 ± 0.092	3.672LeuPhe: 3.672 ± 0.053	8.972LeuGly: 8.972 ± 0.094	2.298LeuHis: 2.298 ± 0.048	4.697LeuIle: 4.697 ± 0.062	3.701LeuLys: 3.701 ± 0.069	11.54LeuLeu: 11.54 ± 0.125	2.253LeuMet: 2.253 ± 0.044	2.658LeuAsn: 2.658 ± 0.051	6.54LeuPro: 6.54 ± 0.072	3.782LeuGln: 3.782 ± 0.059	8.291LeuArg: 8.291 ± 0.107	6.038LeuSer: 6.038 ± 0.069	5.38LeuThr: 5.38 ± 0.074	7.849LeuVal: 7.849 ± 0.087	1.258LeuTrp: 1.258 ± 0.037	2.014LeuTyr: 2.014 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.68MetAla: 2.68 ± 0.05	0.159MetCys: 0.159 ± 0.011	1.097MetAsp: 1.097 ± 0.03	1.028MetGlu: 1.028 ± 0.03	0.601MetPhe: 0.601 ± 0.023	1.616MetGly: 1.616 ± 0.038	0.456MetHis: 0.456 ± 0.018	0.972MetIle: 0.972 ± 0.03	0.925MetLys: 0.925 ± 0.03	2.428MetLeu: 2.428 ± 0.046	0.532MetMet: 0.532 ± 0.025	0.786MetAsn: 0.786 ± 0.025	1.411MetPro: 1.411 ± 0.037	0.906MetGln: 0.906 ± 0.027	1.51MetArg: 1.51 ± 0.035	1.613MetSer: 1.613 ± 0.039	1.25MetThr: 1.25 ± 0.028	1.452MetVal: 1.452 ± 0.037	0.198MetTrp: 0.198 ± 0.013	0.343MetTyr: 0.343 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.009AsnAla: 3.009 ± 0.061	0.268AsnCys: 0.268 ± 0.015	1.29AsnAsp: 1.29 ± 0.039	1.251AsnGlu: 1.251 ± 0.034	0.93AsnPhe: 0.93 ± 0.029	2.154AsnGly: 2.154 ± 0.054	0.523AsnHis: 0.523 ± 0.021	1.224AsnIle: 1.224 ± 0.038	0.798AsnLys: 0.798 ± 0.026	2.793AsnLeu: 2.793 ± 0.056	0.547AsnMet: 0.547 ± 0.02	0.695AsnAsn: 0.695 ± 0.029	1.879AsnPro: 1.879 ± 0.036	0.868AsnGln: 0.868 ± 0.03	1.819AsnArg: 1.819 ± 0.038	1.086AsnSer: 1.086 ± 0.032	1.317AsnThr: 1.317 ± 0.034	1.713AsnVal: 1.713 ± 0.038	0.406AsnTrp: 0.406 ± 0.02	0.632AsnTyr: 0.632 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	8.013ProAla: 8.013 ± 0.103	0.418ProCys: 0.418 ± 0.018	3.608ProAsp: 3.608 ± 0.059	3.741ProGlu: 3.741 ± 0.061	1.803ProPhe: 1.803 ± 0.039	4.888ProGly: 4.888 ± 0.068	1.067ProHis: 1.067 ± 0.029	1.931ProIle: 1.931 ± 0.036	1.457ProLys: 1.457 ± 0.041	5.418ProLeu: 5.418 ± 0.077	1.092ProMet: 1.092 ± 0.029	1.209ProAsn: 1.209 ± 0.03	3.049ProPro: 3.049 ± 0.07	1.849ProGln: 1.849 ± 0.044	3.31ProArg: 3.31 ± 0.057	2.488ProSer: 2.488 ± 0.048	2.452ProThr: 2.452 ± 0.053	4.218ProVal: 4.218 ± 0.063	0.722ProTrp: 0.722 ± 0.023	1.107ProTyr: 1.107 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	5.219GlnAla: 5.219 ± 0.069	0.267GlnCys: 0.267 ± 0.015	1.443GlnAsp: 1.443 ± 0.033	1.484GlnGlu: 1.484 ± 0.038	1.102GlnPhe: 1.102 ± 0.024	2.663GlnGly: 2.663 ± 0.05	0.812GlnHis: 0.812 ± 0.026	1.741GlnIle: 1.741 ± 0.034	1.095GlnLys: 1.095 ± 0.033	4.167GlnLeu: 4.167 ± 0.069	0.809GlnMet: 0.809 ± 0.027	0.772GlnAsn: 0.772 ± 0.023	2.17GlnPro: 2.17 ± 0.038	1.51GlnGln: 1.51 ± 0.043	2.932GlnArg: 2.932 ± 0.06	1.661GlnSer: 1.661 ± 0.038	1.674GlnThr: 1.674 ± 0.038	2.752GlnVal: 2.752 ± 0.05	0.499GlnTrp: 0.499 ± 0.022	0.643GlnTyr: 0.643 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.762ArgAla: 7.762 ± 0.085	0.689ArgCys: 0.689 ± 0.024	3.927ArgAsp: 3.927 ± 0.058	4.508ArgGlu: 4.508 ± 0.07	3.051ArgPhe: 3.051 ± 0.058	4.801ArgGly: 4.801 ± 0.066	2.034ArgHis: 2.034 ± 0.049	3.782ArgIle: 3.782 ± 0.055	2.35ArgLys: 2.35 ± 0.045	9.397ArgLeu: 9.397 ± 0.13	1.77ArgMet: 1.77 ± 0.037	1.91ArgAsn: 1.91 ± 0.041	3.658ArgPro: 3.658 ± 0.06	3.217ArgGln: 3.217 ± 0.061	5.87ArgArg: 5.87 ± 0.091	3.77ArgSer: 3.77 ± 0.062	2.686ArgThr: 2.686 ± 0.047	5.193ArgVal: 5.193 ± 0.071	1.057ArgTrp: 1.057 ± 0.032	1.912ArgTyr: 1.912 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.195SerAla: 6.195 ± 0.093	0.446SerCys: 0.446 ± 0.022	2.58SerAsp: 2.58 ± 0.05	2.662SerGlu: 2.662 ± 0.049	2.112SerPhe: 2.112 ± 0.05	5.164SerGly: 5.164 ± 0.115	1.172SerHis: 1.172 ± 0.03	2.321SerIle: 2.321 ± 0.053	1.482SerLys: 1.482 ± 0.032	6.102SerLeu: 6.102 ± 0.072	1.092SerMet: 1.092 ± 0.034	1.324SerAsn: 1.324 ± 0.039	2.972SerPro: 2.972 ± 0.06	1.681SerGln: 1.681 ± 0.034	3.699SerArg: 3.699 ± 0.07	2.858SerSer: 2.858 ± 0.062	2.64SerThr: 2.64 ± 0.067	3.789SerVal: 3.789 ± 0.064	0.654SerTrp: 0.654 ± 0.023	1.177SerTyr: 1.177 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	5.541ThrAla: 5.541 ± 0.077	0.397ThrCys: 0.397 ± 0.019	2.54ThrAsp: 2.54 ± 0.055	2.435ThrGlu: 2.435 ± 0.041	1.448ThrPhe: 1.448 ± 0.045	4.405ThrGly: 4.405 ± 0.094	1.079ThrHis: 1.079 ± 0.029	2.015ThrIle: 2.015 ± 0.055	1.175ThrLys: 1.175 ± 0.032	6.227ThrLeu: 6.227 ± 0.095	0.86ThrMet: 0.86 ± 0.026	1.136ThrAsn: 1.136 ± 0.04	3.424ThrPro: 3.424 ± 0.055	1.578ThrGln: 1.578 ± 0.035	3.541ThrArg: 3.541 ± 0.053	2.28ThrSer: 2.28 ± 0.059	2.543ThrThr: 2.543 ± 0.071	3.752ThrVal: 3.752 ± 0.096	0.576ThrTrp: 0.576 ± 0.024	1.04ThrTyr: 1.04 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	9.216ValAla: 9.216 ± 0.095	0.68ValCys: 0.68 ± 0.026	4.238ValAsp: 4.238 ± 0.052	4.569ValGlu: 4.569 ± 0.067	2.77ValPhe: 2.77 ± 0.05	5.796ValGly: 5.796 ± 0.068	1.394ValHis: 1.394 ± 0.032	3.444ValIle: 3.444 ± 0.056	2.455ValLys: 2.455 ± 0.055	7.995ValLeu: 7.995 ± 0.09	1.74ValMet: 1.74 ± 0.04	1.8ValAsn: 1.8 ± 0.043	3.563ValPro: 3.563 ± 0.053	2.359ValGln: 2.359 ± 0.052	4.896ValArg: 4.896 ± 0.07	4.399ValSer: 4.399 ± 0.068	3.759ValThr: 3.759 ± 0.085	6.139ValVal: 6.139 ± 0.083	0.931ValTrp: 0.931 ± 0.031	1.314ValTyr: 1.314 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.308TrpAla: 1.308 ± 0.033	0.148TrpCys: 0.148 ± 0.012	0.59TrpAsp: 0.59 ± 0.023	0.644TrpGlu: 0.644 ± 0.02	0.495TrpPhe: 0.495 ± 0.022	0.875TrpGly: 0.875 ± 0.029	0.339TrpHis: 0.339 ± 0.019	0.595TrpIle: 0.595 ± 0.022	0.481TrpLys: 0.481 ± 0.018	2.068TrpLeu: 2.068 ± 0.046	0.354TrpMet: 0.354 ± 0.016	0.384TrpAsn: 0.384 ± 0.017	0.66TrpPro: 0.66 ± 0.025	0.718TrpGln: 0.718 ± 0.026	1.174TrpArg: 1.174 ± 0.037	0.731TrpSer: 0.731 ± 0.024	0.556TrpThr: 0.556 ± 0.02	0.993TrpVal: 0.993 ± 0.026	0.237TrpTrp: 0.237 ± 0.016	0.253TrpTyr: 0.253 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.439TyrAla: 2.439 ± 0.051	0.253TyrCys: 0.253 ± 0.014	1.189TyrAsp: 1.189 ± 0.03	1.009TyrGlu: 1.009 ± 0.031	0.883TyrPhe: 0.883 ± 0.027	1.859TyrGly: 1.859 ± 0.042	0.486TyrHis: 0.486 ± 0.022	0.776TyrIle: 0.776 ± 0.021	0.66TyrLys: 0.66 ± 0.025	2.459TyrLeu: 2.459 ± 0.042	0.387TyrMet: 0.387 ± 0.016	0.578TyrAsn: 0.578 ± 0.024	1.111TyrPro: 1.111 ± 0.033	0.799TyrGln: 0.799 ± 0.026	1.9TyrArg: 1.9 ± 0.04	1.086TyrSer: 1.086 ± 0.03	1.127TyrThr: 1.127 ± 0.035	1.606TyrVal: 1.606 ± 0.034	0.326TyrTrp: 0.326 ± 0.017	0.529TyrTyr: 0.529 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3918 proteins (1310892 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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