Teladorsagia circumcincta (Brown stomach worm) (Ostertagia circumcincta)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Strongylida; Trichostrongyloidea; Haemonchidae; Teladorsagia

Average proteome isoelectric point is 6.67

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 25373 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A2G9UR19|A0A2G9UR19_TELCI SEP domain protein OS=Teladorsagia circumcincta OX=45464 GN=TELCIR_05363 PE=3 SV=1
MM1 pKa = 7.91DD2 pKa = 5.37PVGSDD7 pKa = 3.27ATGLTPMDD15 pKa = 4.36PVGSDD20 pKa = 3.26ATGLTPMDD28 pKa = 4.24PVASGDD34 pKa = 3.82TVLTPMLPTTSDD46 pKa = 3.0ATGLTFTDD54 pKa = 3.96PTGSDD59 pKa = 3.04ATGLTFTDD67 pKa = 4.23PAGSDD72 pKa = 3.22ATGLTFTDD80 pKa = 4.43PADD83 pKa = 3.59SDD85 pKa = 4.35AAGLTPMDD93 pKa = 4.09PTGSDD98 pKa = 3.26NTGLPPVDD106 pKa = 3.54PTGSDD111 pKa = 3.39VTGLIPIDD119 pKa = 3.64PTGSDD124 pKa = 3.62VTGLTPMDD132 pKa = 3.75PTGSDD137 pKa = 3.52VTGLTPMDD145 pKa = 3.97PTGSDD150 pKa = 3.27ATGLTPMDD158 pKa = 4.63SGCSDD163 pKa = 3.22AAGFGVYY170 pKa = 9.43EE171 pKa = 3.7NHH173 pKa = 5.71FRR175 pKa = 11.84EE176 pKa = 4.69VEE178 pKa = 4.22HH179 pKa = 6.69CAHH182 pKa = 7.14GYY184 pKa = 10.65GDD186 pKa = 4.06DD187 pKa = 3.65RR188 pKa = 11.84HH189 pKa = 7.27NEE191 pKa = 4.14DD192 pKa = 3.75VLHH195 pKa = 6.49DD196 pKa = 3.94HH197 pKa = 7.12SRR199 pKa = 11.84DD200 pKa = 3.16CDD202 pKa = 3.79YY203 pKa = 11.34VHH205 pKa = 7.33GYY207 pKa = 9.38LRR209 pKa = 11.84YY210 pKa = 9.6VPLLVKK216 pKa = 9.15EE217 pKa = 4.39TTPVRR222 pKa = 11.84EE223 pKa = 4.23DD224 pKa = 3.55SVPQHH229 pKa = 6.37IDD231 pKa = 3.23EE232 pKa = 5.3PGHH235 pKa = 5.22YY236 pKa = 10.19SRR238 pKa = 11.84VPDD241 pKa = 4.2ANQLEE246 pKa = 4.46

Molecular weight:
25.43 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A2G9UV75|A0A2G9UV75_TELCI PQ loop repeat protein OS=Teladorsagia circumcincta OX=45464 GN=TELCIR_03938 PE=4 SV=1
MM1 pKa = 7.32KK2 pKa = 10.15RR3 pKa = 11.84GAAGKK8 pKa = 9.74SSKK11 pKa = 10.26SSKK14 pKa = 9.36SSKK17 pKa = 9.25SRR19 pKa = 11.84RR20 pKa = 11.84AGSGKK25 pKa = 9.78SGKK28 pKa = 8.75SSRR31 pKa = 11.84SRR33 pKa = 11.84GSKK36 pKa = 9.42SGRR39 pKa = 11.84SRR41 pKa = 11.84RR42 pKa = 11.84KK43 pKa = 8.77GKK45 pKa = 9.65SSRR48 pKa = 11.84SSRR51 pKa = 11.84SKK53 pKa = 10.01SRR55 pKa = 11.84RR56 pKa = 11.84SKK58 pKa = 10.67GSRR61 pKa = 11.84SSKK64 pKa = 9.07SRR66 pKa = 11.84RR67 pKa = 11.84GRR69 pKa = 11.84SKK71 pKa = 10.49SSKK74 pKa = 9.3SKK76 pKa = 10.1SGRR79 pKa = 11.84SRR81 pKa = 11.84KK82 pKa = 8.35SRR84 pKa = 11.84RR85 pKa = 11.84SRR87 pKa = 11.84KK88 pKa = 6.72SQRR91 pKa = 11.84GSRR94 pKa = 11.84SRR96 pKa = 11.84RR97 pKa = 11.84GKK99 pKa = 9.29SRR101 pKa = 11.84RR102 pKa = 11.84SKK104 pKa = 10.52SSRR107 pKa = 11.84SSKK110 pKa = 10.09SKK112 pKa = 10.2SRR114 pKa = 11.84RR115 pKa = 11.84SKK117 pKa = 10.45SKK119 pKa = 10.26RR120 pKa = 11.84EE121 pKa = 3.84SGSRR125 pKa = 11.84RR126 pKa = 11.84SKK128 pKa = 9.94SSRR131 pKa = 11.84SARR134 pKa = 11.84TTPGSCC140 pKa = 4.06

Molecular weight:
15.32 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

25373

0

25373

5444164

20

4415

214.6

24.08

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.425 ± 0.017

2.056 ± 0.012

5.617 ± 0.015

6.798 ± 0.019

3.937 ± 0.012

6.149 ± 0.025

2.393 ± 0.008

5.227 ± 0.012

5.888 ± 0.018

8.622 ± 0.021

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.727 ± 0.01

4.021 ± 0.012

5.284 ± 0.024

3.868 ± 0.014

6.13 ± 0.019

7.321 ± 0.018

5.591 ± 0.02

6.7 ± 0.015

1.162 ± 0.007

3.084 ± 0.011

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski