Amino acid dipepetide frequency for Magnetospirillum marisnigri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.093AlaAla: 18.093 ± 0.236	1.291AlaCys: 1.291 ± 0.037	6.976AlaAsp: 6.976 ± 0.089	8.941AlaGlu: 8.941 ± 0.119	4.008AlaPhe: 4.008 ± 0.066	9.838AlaGly: 9.838 ± 0.136	2.347AlaHis: 2.347 ± 0.049	5.615AlaIle: 5.615 ± 0.066	4.627AlaLys: 4.627 ± 0.068	13.533AlaLeu: 13.533 ± 0.154	3.661AlaMet: 3.661 ± 0.053	2.984AlaAsn: 2.984 ± 0.069	5.402AlaPro: 5.402 ± 0.091	3.959AlaGln: 3.959 ± 0.073	8.651AlaArg: 8.651 ± 0.124	6.5AlaSer: 6.5 ± 0.1	5.883AlaThr: 5.883 ± 0.128	9.683AlaVal: 9.683 ± 0.101	1.619AlaTrp: 1.619 ± 0.042	2.31AlaTyr: 2.31 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	1.016CysAla: 1.016 ± 0.033	0.135CysCys: 0.135 ± 0.01	0.637CysAsp: 0.637 ± 0.022	0.471CysGlu: 0.471 ± 0.022	0.337CysPhe: 0.337 ± 0.016	1.039CysGly: 1.039 ± 0.035	0.318CysHis: 0.318 ± 0.018	0.43CysIle: 0.43 ± 0.019	0.282CysLys: 0.282 ± 0.015	0.925CysLeu: 0.925 ± 0.028	0.179CysMet: 0.179 ± 0.01	0.216CysAsn: 0.216 ± 0.013	0.581CysPro: 0.581 ± 0.025	0.263CysGln: 0.263 ± 0.015	0.821CysArg: 0.821 ± 0.026	0.482CysSer: 0.482 ± 0.024	0.459CysThr: 0.459 ± 0.019	0.661CysVal: 0.661 ± 0.022	0.122CysTrp: 0.122 ± 0.01	0.215CysTyr: 0.215 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.607AspAla: 6.607 ± 0.081	0.587AspCys: 0.587 ± 0.021	3.187AspAsp: 3.187 ± 0.059	3.525AspGlu: 3.525 ± 0.06	2.188AspPhe: 2.188 ± 0.041	5.827AspGly: 5.827 ± 0.087	1.445AspHis: 1.445 ± 0.033	3.14AspIle: 3.14 ± 0.054	1.971AspLys: 1.971 ± 0.047	6.264AspLeu: 6.264 ± 0.075	1.457AspMet: 1.457 ± 0.032	1.342AspAsn: 1.342 ± 0.035	3.335AspPro: 3.335 ± 0.058	1.826AspGln: 1.826 ± 0.039	4.169AspArg: 4.169 ± 0.063	2.795AspSer: 2.795 ± 0.053	2.766AspThr: 2.766 ± 0.08	3.893AspVal: 3.893 ± 0.054	0.97AspTrp: 0.97 ± 0.028	1.353AspTyr: 1.353 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	8.308GluAla: 8.308 ± 0.102	0.456GluCys: 0.456 ± 0.02	2.942GluAsp: 2.942 ± 0.057	3.25GluGlu: 3.25 ± 0.074	1.783GluPhe: 1.783 ± 0.034	4.171GluGly: 4.171 ± 0.057	1.232GluHis: 1.232 ± 0.033	3.186GluIle: 3.186 ± 0.057	2.091GluLys: 2.091 ± 0.047	5.474GluLeu: 5.474 ± 0.087	1.797GluMet: 1.797 ± 0.043	1.217GluAsn: 1.217 ± 0.035	2.553GluPro: 2.553 ± 0.061	2.06GluGln: 2.06 ± 0.044	4.849GluArg: 4.849 ± 0.089	2.715GluSer: 2.715 ± 0.046	3.263GluThr: 3.263 ± 0.058	4.444GluVal: 4.444 ± 0.064	0.637GluTrp: 0.637 ± 0.024	0.902GluTyr: 0.902 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.119PheAla: 4.119 ± 0.066	0.403PheCys: 0.403 ± 0.019	2.439PheAsp: 2.439 ± 0.047	1.976PheGlu: 1.976 ± 0.039	1.214PhePhe: 1.214 ± 0.035	3.284PheGly: 3.284 ± 0.052	0.774PheHis: 0.774 ± 0.028	1.542PheIle: 1.542 ± 0.039	1.162PheLys: 1.162 ± 0.033	3.237PheLeu: 3.237 ± 0.063	0.756PheMet: 0.756 ± 0.023	0.991PheAsn: 0.991 ± 0.031	1.525PhePro: 1.525 ± 0.04	1.063PheGln: 1.063 ± 0.031	2.19PheArg: 2.19 ± 0.043	1.968PheSer: 1.968 ± 0.042	2.01PheThr: 2.01 ± 0.048	2.482PheVal: 2.482 ± 0.044	0.436PheTrp: 0.436 ± 0.019	0.756PheTyr: 0.756 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	8.82GlyAla: 8.82 ± 0.125	1.008GlyCys: 1.008 ± 0.031	4.761GlyAsp: 4.761 ± 0.077	4.841GlyGlu: 4.841 ± 0.071	3.259GlyPhe: 3.259 ± 0.056	7.959GlyGly: 7.959 ± 0.155	2.117GlyHis: 2.117 ± 0.044	4.571GlyIle: 4.571 ± 0.056	3.483GlyLys: 3.483 ± 0.059	9.493GlyLeu: 9.493 ± 0.135	2.419GlyMet: 2.419 ± 0.041	2.268GlyAsn: 2.268 ± 0.083	3.315GlyPro: 3.315 ± 0.057	2.892GlyGln: 2.892 ± 0.049	6.387GlyArg: 6.387 ± 0.084	4.636GlySer: 4.636 ± 0.137	4.524GlyThr: 4.524 ± 0.154	6.086GlyVal: 6.086 ± 0.078	1.441GlyTrp: 1.441 ± 0.035	2.025GlyTyr: 2.025 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.391HisAla: 2.391 ± 0.048	0.251HisCys: 0.251 ± 0.015	1.362HisAsp: 1.362 ± 0.029	0.998HisGlu: 0.998 ± 0.031	0.896HisPhe: 0.896 ± 0.025	2.067HisGly: 2.067 ± 0.043	0.694HisHis: 0.694 ± 0.025	0.904HisIle: 0.904 ± 0.026	0.563HisLys: 0.563 ± 0.021	2.397HisLeu: 2.397 ± 0.049	0.512HisMet: 0.512 ± 0.018	0.462HisAsn: 0.462 ± 0.021	1.451HisPro: 1.451 ± 0.039	0.686HisGln: 0.686 ± 0.025	1.508HisArg: 1.508 ± 0.039	1.068HisSer: 1.068 ± 0.032	0.829HisThr: 0.829 ± 0.026	1.537HisVal: 1.537 ± 0.036	0.361HisTrp: 0.361 ± 0.02	0.58HisTyr: 0.58 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.992IleAla: 5.992 ± 0.084	0.539IleCys: 0.539 ± 0.02	3.26IleAsp: 3.26 ± 0.052	3.085IleGlu: 3.085 ± 0.06	1.415IlePhe: 1.415 ± 0.037	4.566IleGly: 4.566 ± 0.072	1.045IleHis: 1.045 ± 0.028	2.085IleIle: 2.085 ± 0.046	1.708IleLys: 1.708 ± 0.038	4.396IleLeu: 4.396 ± 0.066	0.953IleMet: 0.953 ± 0.029	1.546IleAsn: 1.546 ± 0.041	2.348IlePro: 2.348 ± 0.045	1.361IleGln: 1.361 ± 0.029	3.412IleArg: 3.412 ± 0.059	2.788IleSer: 2.788 ± 0.056	2.865IleThr: 2.865 ± 0.058	3.118IleVal: 3.118 ± 0.058	0.522IleTrp: 0.522 ± 0.02	0.908IleTyr: 0.908 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	4.751LysAla: 4.751 ± 0.076	0.219LysCys: 0.219 ± 0.013	1.96LysAsp: 1.96 ± 0.048	1.601LysGlu: 1.601 ± 0.042	0.94LysPhe: 0.94 ± 0.027	3.091LysGly: 3.091 ± 0.052	0.59LysHis: 0.59 ± 0.023	1.618LysIle: 1.618 ± 0.041	1.31LysLys: 1.31 ± 0.039	3.354LysLeu: 3.354 ± 0.056	0.921LysMet: 0.921 ± 0.025	0.794LysAsn: 0.794 ± 0.026	2.188LysPro: 2.188 ± 0.051	0.961LysGln: 0.961 ± 0.03	2.342LysArg: 2.342 ± 0.05	1.878LysSer: 1.878 ± 0.04	2.043LysThr: 2.043 ± 0.044	2.884LysVal: 2.884 ± 0.057	0.387LysTrp: 0.387 ± 0.017	0.628LysTyr: 0.628 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	15.396LeuAla: 15.396 ± 0.147	0.929LeuCys: 0.929 ± 0.03	6.748LeuAsp: 6.748 ± 0.064	5.542LeuGlu: 5.542 ± 0.08	3.397LeuPhe: 3.397 ± 0.07	9.16LeuGly: 9.16 ± 0.099	1.974LeuHis: 1.974 ± 0.041	4.446LeuIle: 4.446 ± 0.061	3.7LeuLys: 3.7 ± 0.063	9.946LeuLeu: 9.946 ± 0.135	2.524LeuMet: 2.524 ± 0.047	2.397LeuAsn: 2.397 ± 0.049	5.554LeuPro: 5.554 ± 0.085	2.282LeuGln: 2.282 ± 0.046	6.988LeuArg: 6.988 ± 0.105	6.614LeuSer: 6.614 ± 0.124	5.667LeuThr: 5.667 ± 0.143	8.264LeuVal: 8.264 ± 0.085	1.194LeuTrp: 1.194 ± 0.031	1.885LeuTyr: 1.885 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	3.734MetAla: 3.734 ± 0.063	0.18MetCys: 0.18 ± 0.012	1.445MetAsp: 1.445 ± 0.035	1.43MetGlu: 1.43 ± 0.033	0.703MetPhe: 0.703 ± 0.025	2.143MetGly: 2.143 ± 0.046	0.411MetHis: 0.411 ± 0.018	1.258MetIle: 1.258 ± 0.03	0.988MetLys: 0.988 ± 0.033	2.468MetLeu: 2.468 ± 0.051	0.682MetMet: 0.682 ± 0.025	0.678MetAsn: 0.678 ± 0.023	1.432MetPro: 1.432 ± 0.035	0.633MetGln: 0.633 ± 0.021	1.708MetArg: 1.708 ± 0.037	1.608MetSer: 1.608 ± 0.036	1.869MetThr: 1.869 ± 0.035	2.24MetVal: 2.24 ± 0.04	0.209MetTrp: 0.209 ± 0.012	0.307MetTyr: 0.307 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.981AsnAla: 2.981 ± 0.064	0.256AsnCys: 0.256 ± 0.016	1.461AsnAsp: 1.461 ± 0.054	1.05AsnGlu: 1.05 ± 0.034	0.839AsnPhe: 0.839 ± 0.028	2.231AsnGly: 2.231 ± 0.084	0.548AsnHis: 0.548 ± 0.022	1.268AsnIle: 1.268 ± 0.037	0.706AsnLys: 0.706 ± 0.025	2.648AsnLeu: 2.648 ± 0.061	0.548AsnMet: 0.548 ± 0.022	0.638AsnAsn: 0.638 ± 0.036	1.691AsnPro: 1.691 ± 0.038	0.827AsnGln: 0.827 ± 0.027	1.754AsnArg: 1.754 ± 0.033	1.235AsnSer: 1.235 ± 0.043	1.295AsnThr: 1.295 ± 0.053	1.712AsnVal: 1.712 ± 0.043	0.332AsnTrp: 0.332 ± 0.017	0.558AsnTyr: 0.558 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	6.064ProAla: 6.064 ± 0.098	0.39ProCys: 0.39 ± 0.018	3.696ProAsp: 3.696 ± 0.064	3.596ProGlu: 3.596 ± 0.072	1.771ProPhe: 1.771 ± 0.038	4.585ProGly: 4.585 ± 0.069	1.065ProHis: 1.065 ± 0.034	1.982ProIle: 1.982 ± 0.047	1.772ProLys: 1.772 ± 0.05	5.03ProLeu: 5.03 ± 0.089	1.294ProMet: 1.294 ± 0.028	1.195ProAsn: 1.195 ± 0.029	3.37ProPro: 3.37 ± 0.088	1.479ProGln: 1.479 ± 0.037	2.905ProArg: 2.905 ± 0.061	2.692ProSer: 2.692 ± 0.042	2.348ProThr: 2.348 ± 0.051	4.293ProVal: 4.293 ± 0.066	0.694ProTrp: 0.694 ± 0.024	1.051ProTyr: 1.051 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.324GlnAla: 4.324 ± 0.068	0.244GlnCys: 0.244 ± 0.015	1.445GlnAsp: 1.445 ± 0.035	1.369GlnGlu: 1.369 ± 0.035	0.94GlnPhe: 0.94 ± 0.032	2.666GlnGly: 2.666 ± 0.05	0.588GlnHis: 0.588 ± 0.019	1.644GlnIle: 1.644 ± 0.072	0.89GlnLys: 0.89 ± 0.028	2.858GlnLeu: 2.858 ± 0.077	0.904GlnMet: 0.904 ± 0.042	0.623GlnAsn: 0.623 ± 0.021	1.71GlnPro: 1.71 ± 0.039	0.992GlnGln: 0.992 ± 0.037	2.259GlnArg: 2.259 ± 0.049	1.728GlnSer: 1.728 ± 0.038	1.624GlnThr: 1.624 ± 0.044	2.653GlnVal: 2.653 ± 0.052	0.405GlnTrp: 0.405 ± 0.019	0.56GlnTyr: 0.56 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.555ArgAla: 7.555 ± 0.103	0.596ArgCys: 0.596 ± 0.022	4.189ArgAsp: 4.189 ± 0.065	3.69ArgGlu: 3.69 ± 0.063	2.786ArgPhe: 2.786 ± 0.051	4.441ArgGly: 4.441 ± 0.07	1.914ArgHis: 1.914 ± 0.05	3.773ArgIle: 3.773 ± 0.062	2.411ArgLys: 2.411 ± 0.062	9.1ArgLeu: 9.1 ± 0.12	2.027ArgMet: 2.027 ± 0.045	1.653ArgAsn: 1.653 ± 0.038	3.709ArgPro: 3.709 ± 0.067	2.666ArgGln: 2.666 ± 0.053	5.795ArgArg: 5.795 ± 0.11	3.508ArgSer: 3.508 ± 0.059	2.975ArgThr: 2.975 ± 0.049	4.903ArgVal: 4.903 ± 0.075	0.954ArgTrp: 0.954 ± 0.026	1.487ArgTyr: 1.487 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.226SerAla: 6.226 ± 0.099	0.502SerCys: 0.502 ± 0.022	3.005SerAsp: 3.005 ± 0.065	2.619SerGlu: 2.619 ± 0.046	2.071SerPhe: 2.071 ± 0.049	5.612SerGly: 5.612 ± 0.167	1.219SerHis: 1.219 ± 0.03	2.564SerIle: 2.564 ± 0.054	1.584SerLys: 1.584 ± 0.034	6.044SerLeu: 6.044 ± 0.086	1.353SerMet: 1.353 ± 0.032	1.312SerAsn: 1.312 ± 0.043	2.845SerPro: 2.845 ± 0.051	1.663SerGln: 1.663 ± 0.04	3.697SerArg: 3.697 ± 0.066	3.175SerSer: 3.175 ± 0.096	2.666SerThr: 2.666 ± 0.101	4.191SerVal: 4.191 ± 0.081	0.771SerTrp: 0.771 ± 0.027	1.187SerTyr: 1.187 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.143ThrAla: 6.143 ± 0.139	0.461ThrCys: 0.461 ± 0.02	2.711ThrAsp: 2.711 ± 0.064	2.763ThrGlu: 2.763 ± 0.042	1.842ThrPhe: 1.842 ± 0.042	5.069ThrGly: 5.069 ± 0.128	0.997ThrHis: 0.997 ± 0.028	2.708ThrIle: 2.708 ± 0.066	1.505ThrLys: 1.505 ± 0.038	5.78ThrLeu: 5.78 ± 0.117	1.219ThrMet: 1.219 ± 0.03	1.328ThrAsn: 1.328 ± 0.052	3.109ThrPro: 3.109 ± 0.05	1.597ThrGln: 1.597 ± 0.137	3.036ThrArg: 3.036 ± 0.058	2.753ThrSer: 2.753 ± 0.096	2.939ThrThr: 2.939 ± 0.156	4.63ThrVal: 4.63 ± 0.101	0.626ThrTrp: 0.626 ± 0.023	1.091ThrTyr: 1.091 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	10.028ValAla: 10.028 ± 0.106	0.741ValCys: 0.741 ± 0.024	4.421ValAsp: 4.421 ± 0.066	5.017ValGlu: 5.017 ± 0.065	2.669ValPhe: 2.669 ± 0.053	5.724ValGly: 5.724 ± 0.072	1.398ValHis: 1.398 ± 0.038	3.827ValIle: 3.827 ± 0.059	2.637ValLys: 2.637 ± 0.052	7.957ValLeu: 7.957 ± 0.08	2.143ValMet: 2.143 ± 0.045	2.059ValAsn: 2.059 ± 0.053	3.569ValPro: 3.569 ± 0.062	1.994ValGln: 1.994 ± 0.045	4.703ValArg: 4.703 ± 0.066	4.338ValSer: 4.338 ± 0.07	4.585ValThr: 4.585 ± 0.089	7.063ValVal: 7.063 ± 0.092	0.895ValTrp: 0.895 ± 0.03	1.392ValTyr: 1.392 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.287TrpAla: 1.287 ± 0.037	0.156TrpCys: 0.156 ± 0.012	0.683TrpAsp: 0.683 ± 0.025	0.619TrpGlu: 0.619 ± 0.022	0.443TrpPhe: 0.443 ± 0.019	0.952TrpGly: 0.952 ± 0.03	0.331TrpHis: 0.331 ± 0.018	0.579TrpIle: 0.579 ± 0.021	0.483TrpLys: 0.483 ± 0.021	1.597TrpLeu: 1.597 ± 0.042	0.356TrpMet: 0.356 ± 0.016	0.355TrpAsn: 0.355 ± 0.02	0.626TrpPro: 0.626 ± 0.02	0.522TrpGln: 0.522 ± 0.021	1.283TrpArg: 1.283 ± 0.036	0.732TrpSer: 0.732 ± 0.027	0.709TrpThr: 0.709 ± 0.024	0.91TrpVal: 0.91 ± 0.025	0.235TrpTrp: 0.235 ± 0.014	0.269TrpTyr: 0.269 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.085TyrAla: 2.085 ± 0.045	0.246TyrCys: 0.246 ± 0.014	1.319TyrAsp: 1.319 ± 0.035	0.946TyrGlu: 0.946 ± 0.028	0.827TyrPhe: 0.827 ± 0.029	1.879TyrGly: 1.879 ± 0.041	0.509TyrHis: 0.509 ± 0.023	0.774TyrIle: 0.774 ± 0.025	0.59TyrLys: 0.59 ± 0.02	2.107TyrLeu: 2.107 ± 0.04	0.419TyrMet: 0.419 ± 0.016	0.52TyrAsn: 0.52 ± 0.025	0.958TyrPro: 0.958 ± 0.026	0.699TyrGln: 0.699 ± 0.023	1.677TyrArg: 1.677 ± 0.039	1.094TyrSer: 1.094 ± 0.033	0.988TyrThr: 0.988 ± 0.036	1.511TyrVal: 1.511 ± 0.036	0.316TyrTrp: 0.316 ± 0.016	0.489TyrTyr: 0.489 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4097 proteins (1336618 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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