Avian infectious bursal disease virus (strain Chicken/Cuba/Soroa/1998) (IBDV) (Gumboro disease virus)

Taxonomy: Viruses; Riboviria; Orthornavirae; Birnaviridae; Avibirnavirus; Infectious bursal disease virus

Average proteome isoelectric point is 6.44

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|Q9WI42|POLS_IBDVB Structural polyprotein OS=Avian infectious bursal disease virus (strain Chicken/Cuba/Soroa/1998) OX=645118 PE=1 SV=1
MM1 pKa = 7.63TNLSDD6 pKa = 3.41QTQQIVPFIRR16 pKa = 11.84SLLMPTTGPASIPDD30 pKa = 3.64DD31 pKa = 3.68TLEE34 pKa = 3.92KK35 pKa = 9.68HH36 pKa = 5.47TLRR39 pKa = 11.84SEE41 pKa = 3.92TSTYY45 pKa = 10.97NLTVGDD51 pKa = 4.14TGSGLIVFFPGFPGSIVGAHH71 pKa = 5.48YY72 pKa = 9.25TLQGNGNYY80 pKa = 10.14KK81 pKa = 9.78FDD83 pKa = 3.92QMLLTAQNLPASYY96 pKa = 10.21NYY98 pKa = 9.44CRR100 pKa = 11.84LVSRR104 pKa = 11.84SLTVRR109 pKa = 11.84SSTLPGGVYY118 pKa = 10.67ALNGTINAVTFQGSLSEE135 pKa = 4.27LTDD138 pKa = 3.21VSYY141 pKa = 11.52NGLMSATANINDD153 pKa = 4.22KK154 pKa = 10.59IGNVLVGEE162 pKa = 4.48GVTVLSLPTSYY173 pKa = 11.5DD174 pKa = 2.89LGYY177 pKa = 10.9VRR179 pKa = 11.84LGDD182 pKa = 4.85PIPAIGLDD190 pKa = 3.48PKK192 pKa = 10.43MVATCDD198 pKa = 3.2SSDD201 pKa = 3.38RR202 pKa = 11.84PRR204 pKa = 11.84VYY206 pKa = 10.49TITAADD212 pKa = 4.51DD213 pKa = 3.84YY214 pKa = 11.05QFSSQYY220 pKa = 10.28QPGGVTITLFSANIDD235 pKa = 4.21AITSLSVGGEE245 pKa = 3.94LVFRR249 pKa = 11.84TSVHH253 pKa = 5.56GLVLGATIYY262 pKa = 11.11LIGFDD267 pKa = 3.63GTTVITRR274 pKa = 11.84AVAANNGLTTGTDD287 pKa = 2.87NLMPFNLVIPTNEE300 pKa = 3.25ITQPITSIKK309 pKa = 10.6LEE311 pKa = 4.0IVTSKK316 pKa = 10.91SGGQAGDD323 pKa = 3.41QMSWSARR330 pKa = 11.84GSLAVTIHH338 pKa = 6.06GGNYY342 pKa = 9.04PGALRR347 pKa = 11.84PVTLVAYY354 pKa = 9.1EE355 pKa = 4.18RR356 pKa = 11.84VATGSVVTVAGVSNFEE372 pKa = 5.03LIPNPEE378 pKa = 3.96LAKK381 pKa = 11.03NLVTEE386 pKa = 4.26YY387 pKa = 11.44GRR389 pKa = 11.84FDD391 pKa = 4.12PGAMNYY397 pKa = 7.66TKK399 pKa = 10.75LILSEE404 pKa = 4.11RR405 pKa = 11.84DD406 pKa = 2.95RR407 pKa = 11.84LGIKK411 pKa = 7.3TVWPTRR417 pKa = 11.84EE418 pKa = 3.79YY419 pKa = 10.7TDD421 pKa = 3.6FRR423 pKa = 11.84EE424 pKa = 4.25YY425 pKa = 10.92FMEE428 pKa = 4.29VADD431 pKa = 4.92LNSPLKK437 pKa = 10.41IAGAFGFKK445 pKa = 10.39DD446 pKa = 3.63IIRR449 pKa = 11.84AIRR452 pKa = 11.84RR453 pKa = 11.84IAVPVVSTLFPPAAPLAHH471 pKa = 7.26AIGEE475 pKa = 4.5GVDD478 pKa = 3.58YY479 pKa = 11.29LLGDD483 pKa = 3.95EE484 pKa = 4.72AQAASGTARR493 pKa = 11.84AASGKK498 pKa = 9.96ARR500 pKa = 11.84AASGRR505 pKa = 11.84IRR507 pKa = 11.84QLTLAADD514 pKa = 3.27KK515 pKa = 10.88GYY517 pKa = 10.91EE518 pKa = 4.07VVANLFQVPQNPVVDD533 pKa = 5.83GILASPGVLRR543 pKa = 11.84GAHH546 pKa = 6.39NLDD549 pKa = 3.45CVLRR553 pKa = 11.84EE554 pKa = 4.02GATLFPVVITTVEE567 pKa = 3.82DD568 pKa = 3.49AMTPKK573 pKa = 10.78ALNSKK578 pKa = 8.69MFAVIEE584 pKa = 4.28GVRR587 pKa = 11.84EE588 pKa = 3.92DD589 pKa = 4.45LQPPSQRR596 pKa = 11.84GSFIRR601 pKa = 11.84TLSGHH606 pKa = 5.86RR607 pKa = 11.84VYY609 pKa = 10.95GYY611 pKa = 11.08APDD614 pKa = 3.92GVLPLEE620 pKa = 4.29TGRR623 pKa = 11.84DD624 pKa = 3.85YY625 pKa = 11.49TVVPIDD631 pKa = 4.92DD632 pKa = 3.82VWDD635 pKa = 4.19DD636 pKa = 4.84SIMLSKK642 pKa = 11.0DD643 pKa = 3.59PIPPIVGNSGNLAIAYY659 pKa = 8.15MDD661 pKa = 3.36VFRR664 pKa = 11.84PKK666 pKa = 10.6VPIHH670 pKa = 5.55VAMTGALNACGEE682 pKa = 4.16IEE684 pKa = 4.17KK685 pKa = 10.91VSFRR689 pKa = 11.84STKK692 pKa = 10.15LATAHH697 pKa = 7.1RR698 pKa = 11.84LGLRR702 pKa = 11.84LAGPGAFDD710 pKa = 5.0VNTGPNWATFIKK722 pKa = 10.24RR723 pKa = 11.84FPHH726 pKa = 6.93NPRR729 pKa = 11.84DD730 pKa = 3.86WDD732 pKa = 3.68RR733 pKa = 11.84LPYY736 pKa = 10.78LNLPYY741 pKa = 10.53LPPNAGRR748 pKa = 11.84QYY750 pKa = 9.83HH751 pKa = 6.51LAMAASEE758 pKa = 4.14FKK760 pKa = 9.23EE761 pKa = 4.5TPEE764 pKa = 4.24LEE766 pKa = 4.34SAVRR770 pKa = 11.84AMEE773 pKa = 3.97AAANVDD779 pKa = 3.86PLFQSALSVFMWLEE793 pKa = 3.76EE794 pKa = 4.06NGIVTDD800 pKa = 3.69MANFALSDD808 pKa = 4.05PNAHH812 pKa = 7.07RR813 pKa = 11.84MRR815 pKa = 11.84NFLANAPQAGSKK827 pKa = 7.76SQRR830 pKa = 11.84AKK832 pKa = 10.94YY833 pKa = 8.02GTAGYY838 pKa = 9.76GVEE841 pKa = 4.38ARR843 pKa = 11.84GPTPEE848 pKa = 3.68EE849 pKa = 3.66AQRR852 pKa = 11.84EE853 pKa = 4.02KK854 pKa = 10.55DD855 pKa = 3.34TRR857 pKa = 11.84ISKK860 pKa = 10.43KK861 pKa = 9.06MEE863 pKa = 3.68TMGIYY868 pKa = 10.18FATPEE873 pKa = 3.79WVALNGHH880 pKa = 7.16RR881 pKa = 11.84GPSPGQVKK889 pKa = 9.23YY890 pKa = 9.19WQNKK894 pKa = 8.73RR895 pKa = 11.84EE896 pKa = 4.11IPDD899 pKa = 3.84PNEE902 pKa = 4.54DD903 pKa = 3.6YY904 pKa = 11.22LDD906 pKa = 3.79YY907 pKa = 11.55VHH909 pKa = 7.37AEE911 pKa = 3.96KK912 pKa = 10.86SRR914 pKa = 11.84LASEE918 pKa = 4.11EE919 pKa = 4.0QILRR923 pKa = 11.84AATSIYY929 pKa = 9.8GAPGQAEE936 pKa = 4.26PPQAFIDD943 pKa = 4.24EE944 pKa = 4.38VAKK947 pKa = 10.82VYY949 pKa = 10.07EE950 pKa = 4.43INHH953 pKa = 5.42GRR955 pKa = 11.84GPNQEE960 pKa = 3.86QMKK963 pKa = 10.54DD964 pKa = 3.44LLLTAMEE971 pKa = 4.32MKK973 pKa = 10.22HH974 pKa = 5.91RR975 pKa = 11.84NPRR978 pKa = 11.84RR979 pKa = 11.84ALPKK983 pKa = 10.15PKK985 pKa = 9.54PKK987 pKa = 10.28PNAPTQRR994 pKa = 11.84PPGRR998 pKa = 11.84LGRR1001 pKa = 11.84WIRR1004 pKa = 11.84TVSDD1008 pKa = 3.49EE1009 pKa = 4.72DD1010 pKa = 4.27LEE1012 pKa = 4.35

Molecular weight:
109.72 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|P0C751|VP5_IBDVB Protein VP5 OS=Avian infectious bursal disease virus (strain Chicken/Cuba/Soroa/1998) OX=645118 GN=VP5 PE=3 SV=1
MM1 pKa = 7.68SDD3 pKa = 3.42VFNSPQARR11 pKa = 11.84STISAAFGIKK21 pKa = 8.03PTAGQDD27 pKa = 3.57VEE29 pKa = 4.51EE30 pKa = 4.15LLIPKK35 pKa = 9.41VWVPPEE41 pKa = 4.66DD42 pKa = 3.98PLASPSRR49 pKa = 11.84LAKK52 pKa = 10.1FLRR55 pKa = 11.84EE56 pKa = 3.65NGYY59 pKa = 10.25KK60 pKa = 9.98VLQPRR65 pKa = 11.84SLPEE69 pKa = 3.8NEE71 pKa = 4.84EE72 pKa = 4.32YY73 pKa = 9.31EE74 pKa = 4.26TDD76 pKa = 4.37QILPDD81 pKa = 4.33LAWMRR86 pKa = 11.84QIEE89 pKa = 4.46GAVLKK94 pKa = 8.25PTLSLPIGDD103 pKa = 3.76QEE105 pKa = 4.53YY106 pKa = 10.05FPKK109 pKa = 10.53YY110 pKa = 10.12YY111 pKa = 7.96PTHH114 pKa = 6.68RR115 pKa = 11.84PSKK118 pKa = 8.84EE119 pKa = 3.82KK120 pKa = 10.69PNAYY124 pKa = 9.47PPDD127 pKa = 3.66IALLKK132 pKa = 10.02QMIYY136 pKa = 10.94LFLQVPEE143 pKa = 4.35ANEE146 pKa = 3.96GLKK149 pKa = 10.98DD150 pKa = 3.89EE151 pKa = 4.54VTLLTQNIRR160 pKa = 11.84DD161 pKa = 3.64KK162 pKa = 11.21AYY164 pKa = 10.57GSGTYY169 pKa = 9.05MGQANRR175 pKa = 11.84LVAMKK180 pKa = 10.14EE181 pKa = 4.05VATGRR186 pKa = 11.84NPNKK190 pKa = 10.5DD191 pKa = 3.73PLKK194 pKa = 10.6LGYY197 pKa = 8.52TFEE200 pKa = 6.44SIAQLLDD207 pKa = 2.76ITLPVGPPGEE217 pKa = 4.58DD218 pKa = 3.24DD219 pKa = 4.36KK220 pKa = 11.71PWVPLTRR227 pKa = 11.84VPSRR231 pKa = 11.84MLVLTGDD238 pKa = 3.12VDD240 pKa = 4.05GDD242 pKa = 4.15FEE244 pKa = 5.23VEE246 pKa = 4.76DD247 pKa = 4.24YY248 pKa = 11.13LPKK251 pKa = 10.38INLKK255 pKa = 10.38SSSGLPYY262 pKa = 10.07VGRR265 pKa = 11.84TKK267 pKa = 11.16GEE269 pKa = 4.36TIGEE273 pKa = 4.19MIAISNQFLRR283 pKa = 11.84EE284 pKa = 3.93LSTLLKK290 pKa = 10.53QGAGTKK296 pKa = 10.27GSNKK300 pKa = 9.63KK301 pKa = 10.01KK302 pKa = 9.94LLSMLSDD309 pKa = 3.42YY310 pKa = 10.62WYY312 pKa = 10.51LSCGLLFPKK321 pKa = 10.44AEE323 pKa = 4.52RR324 pKa = 11.84YY325 pKa = 8.79DD326 pKa = 3.43KK327 pKa = 10.66STWLTKK333 pKa = 9.37TRR335 pKa = 11.84NIWSAPSPTHH345 pKa = 7.36LMISMITWPVMSNSPNNVLNIEE367 pKa = 4.55GCPSLYY373 pKa = 10.44KK374 pKa = 10.41FNPFRR379 pKa = 11.84GGLNRR384 pKa = 11.84IVEE387 pKa = 4.74WILAPEE393 pKa = 4.13EE394 pKa = 4.1PKK396 pKa = 11.08ALVYY400 pKa = 10.88ADD402 pKa = 4.13NIYY405 pKa = 10.24IVHH408 pKa = 6.42SNTWYY413 pKa = 10.94SIDD416 pKa = 4.29LEE418 pKa = 4.4KK419 pKa = 11.59GEE421 pKa = 4.61ANCTRR426 pKa = 11.84QHH428 pKa = 5.49MQAAMYY434 pKa = 10.0YY435 pKa = 8.69ILTRR439 pKa = 11.84GWSDD443 pKa = 3.09NGDD446 pKa = 3.46PMFNQTWATFAMNIAPALVVDD467 pKa = 4.6SSCLIMNLQIKK478 pKa = 9.15TYY480 pKa = 10.14GQGSGNAATFINNHH494 pKa = 5.92LLSTLVLDD502 pKa = 3.48QWNLMRR508 pKa = 11.84QPRR511 pKa = 11.84PDD513 pKa = 3.38SEE515 pKa = 4.2EE516 pKa = 3.85FKK518 pKa = 11.08SIEE521 pKa = 4.4DD522 pKa = 3.33KK523 pKa = 11.34LGINFKK529 pKa = 10.15IEE531 pKa = 3.77RR532 pKa = 11.84SIDD535 pKa = 3.93DD536 pKa = 2.97IRR538 pKa = 11.84GKK540 pKa = 10.39LRR542 pKa = 11.84QLVLLAQPGYY552 pKa = 10.59LSGGVEE558 pKa = 4.54PEE560 pKa = 3.89QSSPTVEE567 pKa = 4.37LDD569 pKa = 3.44LLGWSATYY577 pKa = 10.83SKK579 pKa = 11.21DD580 pKa = 3.02LGIYY584 pKa = 10.27VPVLDD589 pKa = 5.2KK590 pKa = 11.27EE591 pKa = 4.59RR592 pKa = 11.84LFCSAAYY599 pKa = 9.04PKK601 pKa = 10.69GVEE604 pKa = 4.06NKK606 pKa = 9.63SLKK609 pKa = 10.27SKK611 pKa = 10.93VGIEE615 pKa = 3.75QAYY618 pKa = 9.5KK619 pKa = 8.92VVRR622 pKa = 11.84YY623 pKa = 7.56EE624 pKa = 3.74ALRR627 pKa = 11.84LVGGWNYY634 pKa = 10.51PLLNKK639 pKa = 9.72ACKK642 pKa = 9.88NNAGAARR649 pKa = 11.84RR650 pKa = 11.84HH651 pKa = 5.68LEE653 pKa = 4.04AKK655 pKa = 10.1GFPLDD660 pKa = 3.58EE661 pKa = 5.47FLAEE665 pKa = 3.87WSEE668 pKa = 3.75LSEE671 pKa = 4.25FGEE674 pKa = 4.21AFEE677 pKa = 4.89GFNIKK682 pKa = 8.97LTVTSEE688 pKa = 4.12SLAEE692 pKa = 4.17LNKK695 pKa = 9.9PVPPKK700 pKa = 9.86PPNVNRR706 pKa = 11.84PVNTGGLKK714 pKa = 10.34AVSNALKK721 pKa = 9.43TGRR724 pKa = 11.84YY725 pKa = 8.86RR726 pKa = 11.84NEE728 pKa = 3.92AGLSGLVLLATARR741 pKa = 11.84SRR743 pKa = 11.84LQDD746 pKa = 3.35AVKK749 pKa = 10.7AKK751 pKa = 10.94AEE753 pKa = 3.94AEE755 pKa = 4.15KK756 pKa = 10.69LHH758 pKa = 6.52KK759 pKa = 10.57SKK761 pKa = 10.83PDD763 pKa = 3.84DD764 pKa = 4.69PDD766 pKa = 5.73ADD768 pKa = 3.12WFEE771 pKa = 4.42RR772 pKa = 11.84SEE774 pKa = 4.24TLSDD778 pKa = 3.95LLEE781 pKa = 4.43KK782 pKa = 10.72ADD784 pKa = 3.58IASKK788 pKa = 9.84VAHH791 pKa = 6.17SALVEE796 pKa = 4.02TSDD799 pKa = 4.36ALEE802 pKa = 4.48AVQSTSVYY810 pKa = 7.57TPKK813 pKa = 10.61YY814 pKa = 9.41PEE816 pKa = 3.92VKK818 pKa = 10.55NPQTASNPVVGLHH831 pKa = 6.53LPAKK835 pKa = 10.0RR836 pKa = 11.84ATGVQAALLGAGTSRR851 pKa = 11.84PMGMEE856 pKa = 3.61APTRR860 pKa = 11.84SKK862 pKa = 11.17NAVKK866 pKa = 9.47MAKK869 pKa = 9.48RR870 pKa = 11.84RR871 pKa = 11.84QRR873 pKa = 11.84QKK875 pKa = 10.89EE876 pKa = 4.04SRR878 pKa = 11.84QQ879 pKa = 3.42

Molecular weight:
97.68 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

2036

145

1012

678.7

74.64

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.644 ± 1.039

0.835 ± 0.926

5.157 ± 0.734

5.796 ± 0.64

2.898 ± 0.433

7.417 ± 0.814

1.719 ± 1.204

4.568 ± 0.96

5.059 ± 1.304

9.823 ± 0.948

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.21 ± 0.352

4.961 ± 0.23

7.318 ± 0.062

3.487 ± 0.485

5.648 ± 0.985

6.974 ± 0.737

6.139 ± 0.774

6.532 ± 0.565

1.473 ± 0.556

3.34 ± 0.769

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski