Amino acid dipepetide frequency for Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.265AlaAla: 7.265 ± 0.075	1.498AlaCys: 1.498 ± 0.021	3.508AlaAsp: 3.508 ± 0.031	4.529AlaGlu: 4.529 ± 0.041	3.15AlaPhe: 3.15 ± 0.026	3.848AlaGly: 3.848 ± 0.039	1.554AlaHis: 1.554 ± 0.018	3.662AlaIle: 3.662 ± 0.036	3.473AlaLys: 3.473 ± 0.028	7.133AlaLeu: 7.133 ± 0.05	1.652AlaMet: 1.652 ± 0.02	2.941AlaAsn: 2.941 ± 0.027	3.655AlaPro: 3.655 ± 0.037	2.466AlaGln: 2.466 ± 0.028	3.752AlaArg: 3.752 ± 0.033	7.172AlaSer: 7.172 ± 0.051	4.669AlaThr: 4.669 ± 0.035	5.11AlaVal: 5.11 ± 0.036	0.74AlaTrp: 0.74 ± 0.013	1.901AlaTyr: 1.901 ± 0.022	0.002AlaXaa: 0.002 ± 0.001
Cys	1.358CysAla: 1.358 ± 0.017	0.625CysCys: 0.625 ± 0.016	1.071CysAsp: 1.071 ± 0.019	1.191CysGlu: 1.191 ± 0.021	0.936CysPhe: 0.936 ± 0.016	1.422CysGly: 1.422 ± 0.022	0.608CysHis: 0.608 ± 0.014	1.13CysIle: 1.13 ± 0.015	0.873CysLys: 0.873 ± 0.018	2.524CysLeu: 2.524 ± 0.029	0.436CysMet: 0.436 ± 0.009	0.761CysAsn: 0.761 ± 0.013	1.165CysPro: 1.165 ± 0.024	0.831CysGln: 0.831 ± 0.016	1.409CysArg: 1.409 ± 0.022	1.805CysSer: 1.805 ± 0.023	1.084CysThr: 1.084 ± 0.018	1.422CysVal: 1.422 ± 0.023	0.227CysTrp: 0.227 ± 0.007	0.561CysTyr: 0.561 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	3.783AspAla: 3.783 ± 0.032	1.067AspCys: 1.067 ± 0.018	3.243AspAsp: 3.243 ± 0.046	3.874AspGlu: 3.874 ± 0.037	2.362AspPhe: 2.362 ± 0.022	3.378AspGly: 3.378 ± 0.044	1.004AspHis: 1.004 ± 0.014	2.593AspIle: 2.593 ± 0.027	2.003AspLys: 2.003 ± 0.024	5.137AspLeu: 5.137 ± 0.043	1.008AspMet: 1.008 ± 0.018	1.805AspAsn: 1.805 ± 0.018	2.625AspPro: 2.625 ± 0.029	1.591AspGln: 1.591 ± 0.018	2.736AspArg: 2.736 ± 0.028	4.224AspSer: 4.224 ± 0.038	2.462AspThr: 2.462 ± 0.021	3.566AspVal: 3.566 ± 0.033	0.628AspTrp: 0.628 ± 0.013	1.519AspTyr: 1.519 ± 0.02	0.001AspXaa: 0.001 ± 0.0
Glu	5.238GluAla: 5.238 ± 0.043	1.186GluCys: 1.186 ± 0.019	3.663GluAsp: 3.663 ± 0.034	6.234GluGlu: 6.234 ± 0.081	2.103GluPhe: 2.103 ± 0.024	3.532GluGly: 3.532 ± 0.036	1.264GluHis: 1.264 ± 0.017	3.02GluIle: 3.02 ± 0.03	3.501GluLys: 3.501 ± 0.039	5.448GluLeu: 5.448 ± 0.044	1.629GluMet: 1.629 ± 0.019	2.588GluAsn: 2.588 ± 0.027	2.338GluPro: 2.338 ± 0.03	2.212GluGln: 2.212 ± 0.023	3.736GluArg: 3.736 ± 0.039	4.636GluSer: 4.636 ± 0.031	3.286GluThr: 3.286 ± 0.028	4.533GluVal: 4.533 ± 0.035	0.657GluTrp: 0.657 ± 0.013	1.485GluTyr: 1.485 ± 0.021	0.002GluXaa: 0.002 ± 0.001
Phe	2.829PheAla: 2.829 ± 0.026	1.0PheCys: 1.0 ± 0.018	2.246PheAsp: 2.246 ± 0.024	2.203PheGlu: 2.203 ± 0.022	1.895PhePhe: 1.895 ± 0.025	2.382PheGly: 2.382 ± 0.028	1.1PheHis: 1.1 ± 0.017	2.134PheIle: 2.134 ± 0.023	1.645PheLys: 1.645 ± 0.02	4.087PheLeu: 4.087 ± 0.038	0.837PheMet: 0.837 ± 0.015	1.646PheAsn: 1.646 ± 0.021	1.979PhePro: 1.979 ± 0.022	1.427PheGln: 1.427 ± 0.017	2.238PheArg: 2.238 ± 0.025	3.576PheSer: 3.576 ± 0.031	2.354PheThr: 2.354 ± 0.022	2.739PheVal: 2.739 ± 0.027	0.463PheTrp: 0.463 ± 0.01	1.364PheTyr: 1.364 ± 0.019	0.001PheXaa: 0.001 ± 0.001
Gly	3.831GlyAla: 3.831 ± 0.038	1.252GlyCys: 1.252 ± 0.02	3.273GlyAsp: 3.273 ± 0.04	3.636GlyGlu: 3.636 ± 0.058	2.284GlyPhe: 2.284 ± 0.026	5.568GlyGly: 5.568 ± 0.071	1.364GlyHis: 1.364 ± 0.021	2.808GlyIle: 2.808 ± 0.032	2.716GlyLys: 2.716 ± 0.027	5.159GlyLeu: 5.159 ± 0.041	1.237GlyMet: 1.237 ± 0.02	2.239GlyAsn: 2.239 ± 0.023	2.59GlyPro: 2.59 ± 0.083	1.984GlyGln: 1.984 ± 0.026	3.55GlyArg: 3.55 ± 0.032	5.296GlySer: 5.296 ± 0.045	3.157GlyThr: 3.157 ± 0.03	3.99GlyVal: 3.99 ± 0.034	0.649GlyTrp: 0.649 ± 0.014	1.577GlyTyr: 1.577 ± 0.021	0.002GlyXaa: 0.002 ± 0.001
His	1.452HisAla: 1.452 ± 0.018	0.643HisCys: 0.643 ± 0.013	0.972HisAsp: 0.972 ± 0.014	1.225HisGlu: 1.225 ± 0.016	1.236HisPhe: 1.236 ± 0.017	1.289HisGly: 1.289 ± 0.019	1.077HisHis: 1.077 ± 0.023	1.237HisIle: 1.237 ± 0.019	0.919HisLys: 0.919 ± 0.015	3.041HisLeu: 3.041 ± 0.027	0.502HisMet: 0.502 ± 0.011	0.873HisAsn: 0.873 ± 0.014	1.634HisPro: 1.634 ± 0.023	1.245HisGln: 1.245 ± 0.02	1.805HisArg: 1.805 ± 0.023	2.278HisSer: 2.278 ± 0.026	1.241HisThr: 1.241 ± 0.016	1.401HisVal: 1.401 ± 0.016	0.341HisTrp: 0.341 ± 0.008	0.761HisTyr: 0.761 ± 0.011	0.001HisXaa: 0.001 ± 0.0
Ile	3.566IleAla: 3.566 ± 0.03	1.229IleCys: 1.229 ± 0.018	2.688IleAsp: 2.688 ± 0.028	2.886IleGlu: 2.886 ± 0.03	2.207IlePhe: 2.207 ± 0.025	2.743IleGly: 2.743 ± 0.033	1.249IleHis: 1.249 ± 0.016	2.506IleIle: 2.506 ± 0.029	2.192IleLys: 2.192 ± 0.028	4.71IleLeu: 4.71 ± 0.04	0.942IleMet: 0.942 ± 0.016	2.063IleAsn: 2.063 ± 0.023	2.737IlePro: 2.737 ± 0.029	1.813IleGln: 1.813 ± 0.022	2.906IleArg: 2.906 ± 0.027	4.411IleSer: 4.411 ± 0.036	2.891IleThr: 2.891 ± 0.024	3.162IleVal: 3.162 ± 0.029	0.535IleTrp: 0.535 ± 0.011	1.484IleTyr: 1.484 ± 0.019	0.001IleXaa: 0.001 ± 0.001
Lys	3.43LysAla: 3.43 ± 0.029	0.912LysCys: 0.912 ± 0.018	2.18LysAsp: 2.18 ± 0.026	3.188LysGlu: 3.188 ± 0.038	1.605LysPhe: 1.605 ± 0.023	2.266LysGly: 2.266 ± 0.041	1.138LysHis: 1.138 ± 0.018	2.25LysIle: 2.25 ± 0.028	2.897LysLys: 2.897 ± 0.037	4.376LysLeu: 4.376 ± 0.038	1.192LysMet: 1.192 ± 0.017	1.812LysAsn: 1.812 ± 0.023	2.424LysPro: 2.424 ± 0.025	1.846LysGln: 1.846 ± 0.024	3.455LysArg: 3.455 ± 0.037	3.931LysSer: 3.931 ± 0.034	2.556LysThr: 2.556 ± 0.026	3.034LysVal: 3.034 ± 0.027	0.515LysTrp: 0.515 ± 0.011	1.235LysTyr: 1.235 ± 0.017	0.002LysXaa: 0.002 ± 0.001
Leu	7.18LeuAla: 7.18 ± 0.048	2.094LeuCys: 2.094 ± 0.027	4.776LeuAsp: 4.776 ± 0.041	5.965LeuGlu: 5.965 ± 0.046	3.946LeuPhe: 3.946 ± 0.035	4.734LeuGly: 4.734 ± 0.039	2.748LeuHis: 2.748 ± 0.027	4.817LeuIle: 4.817 ± 0.038	4.807LeuLys: 4.807 ± 0.037	10.796LeuLeu: 10.796 ± 0.084	2.116LeuMet: 2.116 ± 0.024	3.927LeuAsn: 3.927 ± 0.032	6.217LeuPro: 6.217 ± 0.047	4.413LeuGln: 4.413 ± 0.035	6.72LeuArg: 6.72 ± 0.044	8.755LeuSer: 8.755 ± 0.053	5.747LeuThr: 5.747 ± 0.039	5.956LeuVal: 5.956 ± 0.04	1.027LeuTrp: 1.027 ± 0.014	2.399LeuTyr: 2.399 ± 0.023	0.003LeuXaa: 0.003 ± 0.001
Met	1.78MetAla: 1.78 ± 0.019	0.401MetCys: 0.401 ± 0.01	1.26MetAsp: 1.26 ± 0.019	1.686MetGlu: 1.686 ± 0.019	0.684MetPhe: 0.684 ± 0.013	1.234MetGly: 1.234 ± 0.02	0.575MetHis: 0.575 ± 0.013	0.87MetIle: 0.87 ± 0.015	1.093MetLys: 1.093 ± 0.016	2.046MetLeu: 2.046 ± 0.022	0.515MetMet: 0.515 ± 0.01	0.863MetAsn: 0.863 ± 0.015	1.223MetPro: 1.223 ± 0.018	0.957MetGln: 0.957 ± 0.014	1.45MetArg: 1.45 ± 0.018	1.729MetSer: 1.729 ± 0.02	1.192MetThr: 1.192 ± 0.016	1.379MetVal: 1.379 ± 0.018	0.219MetTrp: 0.219 ± 0.007	0.485MetTyr: 0.485 ± 0.01	0.001MetXaa: 0.001 ± 0.001
Asn	3.054AsnAla: 3.054 ± 0.027	0.891AsnCys: 0.891 ± 0.015	2.01AsnAsp: 2.01 ± 0.027	2.411AsnGlu: 2.411 ± 0.026	1.738AsnPhe: 1.738 ± 0.021	2.621AsnGly: 2.621 ± 0.032	0.962AsnHis: 0.962 ± 0.016	1.971AsnIle: 1.971 ± 0.023	1.605AsnLys: 1.605 ± 0.022	4.044AsnLeu: 4.044 ± 0.033	0.788AsnMet: 0.788 ± 0.013	1.588AsnAsn: 1.588 ± 0.022	2.177AsnPro: 2.177 ± 0.021	1.543AsnGln: 1.543 ± 0.018	2.367AsnArg: 2.367 ± 0.021	3.512AsnSer: 3.512 ± 0.03	2.112AsnThr: 2.112 ± 0.021	2.569AsnVal: 2.569 ± 0.026	0.476AsnTrp: 0.476 ± 0.011	1.166AsnTyr: 1.166 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	3.392ProAla: 3.392 ± 0.032	0.951ProCys: 0.951 ± 0.017	2.512ProAsp: 2.512 ± 0.032	2.991ProGlu: 2.991 ± 0.03	2.104ProPhe: 2.104 ± 0.025	2.867ProGly: 2.867 ± 0.08	1.46ProHis: 1.46 ± 0.02	2.717ProIle: 2.717 ± 0.029	2.366ProLys: 2.366 ± 0.028	5.558ProLeu: 5.558 ± 0.043	1.089ProMet: 1.089 ± 0.017	2.244ProAsn: 2.244 ± 0.022	6.441ProPro: 6.441 ± 0.083	2.317ProGln: 2.317 ± 0.03	3.016ProArg: 3.016 ± 0.031	6.359ProSer: 6.359 ± 0.056	3.847ProThr: 3.847 ± 0.035	3.397ProVal: 3.397 ± 0.031	0.539ProTrp: 0.539 ± 0.012	1.347ProTyr: 1.347 ± 0.016	0.003ProXaa: 0.003 ± 0.001
Gln	2.615GlnAla: 2.615 ± 0.032	0.831GlnCys: 0.831 ± 0.016	1.419GlnAsp: 1.419 ± 0.02	2.171GlnGlu: 2.171 ± 0.026	1.398GlnPhe: 1.398 ± 0.019	1.637GlnGly: 1.637 ± 0.026	1.219GlnHis: 1.219 ± 0.019	1.97GlnIle: 1.97 ± 0.022	1.918GlnLys: 1.918 ± 0.022	4.229GlnLeu: 4.229 ± 0.038	1.066GlnMet: 1.066 ± 0.016	1.566GlnAsn: 1.566 ± 0.02	2.395GlnPro: 2.395 ± 0.033	2.943GlnGln: 2.943 ± 0.065	2.8GlnArg: 2.8 ± 0.027	3.373GlnSer: 3.373 ± 0.028	2.211GlnThr: 2.211 ± 0.026	2.335GlnVal: 2.335 ± 0.024	0.473GlnTrp: 0.473 ± 0.01	0.905GlnTyr: 0.905 ± 0.014	0.001GlnXaa: 0.001 ± 0.001
Arg	3.811ArgAla: 3.811 ± 0.032	1.415ArgCys: 1.415 ± 0.023	2.722ArgAsp: 2.722 ± 0.024	3.469ArgGlu: 3.469 ± 0.03	2.518ArgPhe: 2.518 ± 0.023	3.383ArgGly: 3.383 ± 0.047	1.817ArgHis: 1.817 ± 0.023	3.212ArgIle: 3.212 ± 0.03	3.179ArgLys: 3.179 ± 0.03	7.066ArgLeu: 7.066 ± 0.038	1.38ArgMet: 1.38 ± 0.018	2.407ArgAsn: 2.407 ± 0.023	3.079ArgPro: 3.079 ± 0.029	2.734ArgGln: 2.734 ± 0.029	5.67ArgArg: 5.67 ± 0.054	5.245ArgSer: 5.245 ± 0.043	3.015ArgThr: 3.015 ± 0.03	3.701ArgVal: 3.701 ± 0.028	0.763ArgTrp: 0.763 ± 0.015	1.701ArgTyr: 1.701 ± 0.022	0.002ArgXaa: 0.002 ± 0.001
Ser	6.79SerAla: 6.79 ± 0.047	1.723SerCys: 1.723 ± 0.024	4.431SerAsp: 4.431 ± 0.033	4.886SerGlu: 4.886 ± 0.037	3.271SerPhe: 3.271 ± 0.024	5.815SerGly: 5.815 ± 0.051	2.193SerHis: 2.193 ± 0.025	4.225SerIle: 4.225 ± 0.033	3.961SerLys: 3.961 ± 0.037	8.706SerLeu: 8.706 ± 0.063	1.834SerMet: 1.834 ± 0.02	3.627SerAsn: 3.627 ± 0.03	5.793SerPro: 5.793 ± 0.052	3.473SerGln: 3.473 ± 0.031	5.38SerArg: 5.38 ± 0.038	11.285SerSer: 11.285 ± 0.112	6.475SerThr: 6.475 ± 0.055	5.822SerVal: 5.822 ± 0.041	0.865SerTrp: 0.865 ± 0.015	1.943SerTyr: 1.943 ± 0.022	0.003SerXaa: 0.003 ± 0.001
Thr	4.807ThrAla: 4.807 ± 0.039	1.212ThrCys: 1.212 ± 0.02	2.832ThrAsp: 2.832 ± 0.026	3.262ThrGlu: 3.262 ± 0.028	2.286ThrPhe: 2.286 ± 0.022	3.429ThrGly: 3.429 ± 0.03	1.282ThrHis: 1.282 ± 0.014	2.726ThrIle: 2.726 ± 0.025	2.429ThrLys: 2.429 ± 0.021	5.33ThrLeu: 5.33 ± 0.037	1.188ThrMet: 1.188 ± 0.016	2.397ThrAsn: 2.397 ± 0.025	3.82ThrPro: 3.82 ± 0.038	1.965ThrGln: 1.965 ± 0.024	2.9ThrArg: 2.9 ± 0.029	6.277ThrSer: 6.277 ± 0.051	4.49ThrThr: 4.49 ± 0.048	3.939ThrVal: 3.939 ± 0.031	0.598ThrTrp: 0.598 ± 0.012	1.47ThrTyr: 1.47 ± 0.02	0.003ThrXaa: 0.003 ± 0.001
Val	5.021ValAla: 5.021 ± 0.033	1.585ValCys: 1.585 ± 0.027	3.883ValAsp: 3.883 ± 0.034	4.408ValGlu: 4.408 ± 0.037	2.625ValPhe: 2.625 ± 0.025	3.967ValGly: 3.967 ± 0.037	1.533ValHis: 1.533 ± 0.017	3.179ValIle: 3.179 ± 0.032	3.009ValLys: 3.009 ± 0.029	5.722ValLeu: 5.722 ± 0.039	1.358ValMet: 1.358 ± 0.016	2.726ValAsn: 2.726 ± 0.025	3.36ValPro: 3.36 ± 0.031	2.235ValGln: 2.235 ± 0.023	3.71ValArg: 3.71 ± 0.026	5.649ValSer: 5.649 ± 0.037	3.803ValThr: 3.803 ± 0.029	4.674ValVal: 4.674 ± 0.044	0.695ValTrp: 0.695 ± 0.015	1.808ValTyr: 1.808 ± 0.021	0.003ValXaa: 0.003 ± 0.001
Trp	0.606TrpAla: 0.606 ± 0.013	0.268TrpCys: 0.268 ± 0.007	0.552TrpAsp: 0.552 ± 0.011	0.559TrpGlu: 0.559 ± 0.014	0.477TrpPhe: 0.477 ± 0.011	0.469TrpGly: 0.469 ± 0.011	0.3TrpHis: 0.3 ± 0.008	0.617TrpIle: 0.617 ± 0.013	0.573TrpLys: 0.573 ± 0.011	1.187TrpLeu: 1.187 ± 0.017	0.317TrpMet: 0.317 ± 0.009	0.504TrpAsn: 0.504 ± 0.011	0.523TrpPro: 0.523 ± 0.012	0.45TrpGln: 0.45 ± 0.01	0.895TrpArg: 0.895 ± 0.014	0.941TrpSer: 0.941 ± 0.017	0.616TrpThr: 0.616 ± 0.012	0.587TrpVal: 0.587 ± 0.013	0.174TrpTrp: 0.174 ± 0.006	0.295TrpTyr: 0.295 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.871TyrAla: 1.871 ± 0.021	0.656TyrCys: 0.656 ± 0.012	1.366TyrAsp: 1.366 ± 0.017	1.515TyrGlu: 1.515 ± 0.021	1.315TyrPhe: 1.315 ± 0.021	1.577TyrGly: 1.577 ± 0.023	0.725TyrHis: 0.725 ± 0.012	1.274TyrIle: 1.274 ± 0.02	1.081TyrLys: 1.081 ± 0.017	2.842TyrLeu: 2.842 ± 0.031	0.553TyrMet: 0.553 ± 0.012	1.027TyrAsn: 1.027 ± 0.015	1.34TyrPro: 1.34 ± 0.016	1.03TyrGln: 1.03 ± 0.015	1.792TyrArg: 1.792 ± 0.022	2.045TyrSer: 2.045 ± 0.022	1.432TyrThr: 1.432 ± 0.018	1.636TyrVal: 1.636 ± 0.021	0.329TyrTrp: 0.329 ± 0.01	0.899TyrTyr: 0.899 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.002XaaGlu: 0.002 ± 0.001	0.003XaaPhe: 0.003 ± 0.001	0.003XaaGly: 0.003 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.002XaaIle: 0.002 ± 0.001	0.001XaaLys: 0.001 ± 0.0	0.003XaaLeu: 0.003 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.002XaaPro: 0.002 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.003XaaArg: 0.003 ± 0.001	0.003XaaSer: 0.003 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.324XaaXaa: 0.324 ± 0.043

Statistics based on 11591 proteins (4628800 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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