Amino acid dipepetide frequency for Pirellulimonas nuda

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.656AlaAla: 17.656 ± 0.161	1.409AlaCys: 1.409 ± 0.025	7.363AlaAsp: 7.363 ± 0.076	7.544AlaGlu: 7.544 ± 0.086	3.652AlaPhe: 3.652 ± 0.051	11.132AlaGly: 11.132 ± 0.097	1.844AlaHis: 1.844 ± 0.035	5.1AlaIle: 5.1 ± 0.062	3.357AlaLys: 3.357 ± 0.05	11.02AlaLeu: 11.02 ± 0.099	2.763AlaMet: 2.763 ± 0.038	2.784AlaAsn: 2.784 ± 0.043	6.872AlaPro: 6.872 ± 0.076	4.229AlaGln: 4.229 ± 0.06	7.345AlaArg: 7.345 ± 0.088	7.26AlaSer: 7.26 ± 0.073	6.216AlaThr: 6.216 ± 0.073	8.636AlaVal: 8.636 ± 0.081	1.903AlaTrp: 1.903 ± 0.036	2.554AlaTyr: 2.554 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.961CysAla: 0.961 ± 0.024	0.274CysCys: 0.274 ± 0.019	0.762CysAsp: 0.762 ± 0.022	0.677CysGlu: 0.677 ± 0.021	0.406CysPhe: 0.406 ± 0.012	1.2CysGly: 1.2 ± 0.033	0.338CysHis: 0.338 ± 0.017	0.364CysIle: 0.364 ± 0.015	0.258CysLys: 0.258 ± 0.015	1.09CysLeu: 1.09 ± 0.023	0.189CysMet: 0.189 ± 0.01	0.244CysAsn: 0.244 ± 0.013	0.645CysPro: 0.645 ± 0.022	0.378CysGln: 0.378 ± 0.014	0.893CysArg: 0.893 ± 0.023	0.574CysSer: 0.574 ± 0.021	0.488CysThr: 0.488 ± 0.016	0.928CysVal: 0.928 ± 0.021	0.195CysTrp: 0.195 ± 0.009	0.311CysTyr: 0.311 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.809AspAla: 7.809 ± 0.074	0.6AspCys: 0.6 ± 0.016	3.701AspAsp: 3.701 ± 0.052	3.668AspGlu: 3.668 ± 0.048	2.247AspPhe: 2.247 ± 0.038	5.97AspGly: 5.97 ± 0.081	1.313AspHis: 1.313 ± 0.03	1.955AspIle: 1.955 ± 0.033	1.458AspLys: 1.458 ± 0.035	5.855AspLeu: 5.855 ± 0.058	0.895AspMet: 0.895 ± 0.022	1.497AspAsn: 1.497 ± 0.034	4.285AspPro: 4.285 ± 0.059	2.247AspGln: 2.247 ± 0.039	4.79AspArg: 4.79 ± 0.063	3.001AspSer: 3.001 ± 0.046	2.397AspThr: 2.397 ± 0.039	3.925AspVal: 3.925 ± 0.05	1.18AspTrp: 1.18 ± 0.026	1.845AspTyr: 1.845 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.09GluAla: 7.09 ± 0.073	0.509GluCys: 0.509 ± 0.018	2.612GluAsp: 2.612 ± 0.046	3.259GluGlu: 3.259 ± 0.059	1.907GluPhe: 1.907 ± 0.035	4.473GluGly: 4.473 ± 0.057	1.273GluHis: 1.273 ± 0.027	2.427GluIle: 2.427 ± 0.041	1.901GluLys: 1.901 ± 0.044	6.601GluLeu: 6.601 ± 0.078	1.235GluMet: 1.235 ± 0.025	1.536GluAsn: 1.536 ± 0.033	3.413GluPro: 3.413 ± 0.044	2.737GluGln: 2.737 ± 0.046	4.448GluArg: 4.448 ± 0.055	3.317GluSer: 3.317 ± 0.043	3.036GluThr: 3.036 ± 0.047	4.283GluVal: 4.283 ± 0.058	0.815GluTrp: 0.815 ± 0.022	1.274GluTyr: 1.274 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	3.724PheAla: 3.724 ± 0.046	0.481PheCys: 0.481 ± 0.015	2.745PheAsp: 2.745 ± 0.042	2.116PheGlu: 2.116 ± 0.038	1.274PhePhe: 1.274 ± 0.033	3.358PheGly: 3.358 ± 0.048	0.648PheHis: 0.648 ± 0.018	1.126PheIle: 1.126 ± 0.024	0.761PheLys: 0.761 ± 0.019	2.931PheLeu: 2.931 ± 0.045	0.543PheMet: 0.543 ± 0.019	1.127PheAsn: 1.127 ± 0.029	1.528PhePro: 1.528 ± 0.031	1.095PheGln: 1.095 ± 0.022	2.18PheArg: 2.18 ± 0.03	2.091PheSer: 2.091 ± 0.036	1.94PheThr: 1.94 ± 0.034	2.578PheVal: 2.578 ± 0.043	0.567PheTrp: 0.567 ± 0.018	0.949PheTyr: 0.949 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	10.482GlyAla: 10.482 ± 0.098	1.103GlyCys: 1.103 ± 0.029	5.595GlyAsp: 5.595 ± 0.07	5.139GlyGlu: 5.139 ± 0.063	3.157GlyPhe: 3.157 ± 0.042	8.444GlyGly: 8.444 ± 0.121	1.567GlyHis: 1.567 ± 0.028	3.05GlyIle: 3.05 ± 0.049	2.944GlyLys: 2.944 ± 0.049	8.194GlyLeu: 8.194 ± 0.074	1.974GlyMet: 1.974 ± 0.03	2.158GlyAsn: 2.158 ± 0.046	4.37GlyPro: 4.37 ± 0.05	3.364GlyGln: 3.364 ± 0.046	6.301GlyArg: 6.301 ± 0.065	5.236GlySer: 5.236 ± 0.073	3.754GlyThr: 3.754 ± 0.06	7.695GlyVal: 7.695 ± 0.074	1.605GlyTrp: 1.605 ± 0.032	2.363GlyTyr: 2.363 ± 0.034	0.0GlyXaa: 0.0 ± 0.0
His	2.419HisAla: 2.419 ± 0.04	0.287HisCys: 0.287 ± 0.012	1.286HisAsp: 1.286 ± 0.028	1.1HisGlu: 1.1 ± 0.026	0.778HisPhe: 0.778 ± 0.021	1.849HisGly: 1.849 ± 0.038	0.565HisHis: 0.565 ± 0.017	0.636HisIle: 0.636 ± 0.017	0.458HisLys: 0.458 ± 0.018	1.862HisLeu: 1.862 ± 0.036	0.316HisMet: 0.316 ± 0.016	0.57HisAsn: 0.57 ± 0.016	1.371HisPro: 1.371 ± 0.031	0.675HisGln: 0.675 ± 0.018	1.465HisArg: 1.465 ± 0.028	1.055HisSer: 1.055 ± 0.024	0.964HisThr: 0.964 ± 0.023	1.479HisVal: 1.479 ± 0.03	0.427HisTrp: 0.427 ± 0.015	0.603HisTyr: 0.603 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	5.43IleAla: 5.43 ± 0.058	0.41IleCys: 0.41 ± 0.014	3.736IleAsp: 3.736 ± 0.043	3.179IleGlu: 3.179 ± 0.041	0.947IlePhe: 0.947 ± 0.023	3.83IleGly: 3.83 ± 0.052	0.825IleHis: 0.825 ± 0.02	1.187IleIle: 1.187 ± 0.031	1.062IleLys: 1.062 ± 0.026	2.648IleLeu: 2.648 ± 0.04	0.46IleMet: 0.46 ± 0.016	1.198IleAsn: 1.198 ± 0.031	1.831IlePro: 1.831 ± 0.037	1.093IleGln: 1.093 ± 0.027	2.478IleArg: 2.478 ± 0.041	2.051IleSer: 2.051 ± 0.035	2.08IleThr: 2.08 ± 0.04	3.34IleVal: 3.34 ± 0.05	0.397IleTrp: 0.397 ± 0.014	0.864IleTyr: 0.864 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.634LysAla: 2.634 ± 0.046	0.255LysCys: 0.255 ± 0.012	1.336LysAsp: 1.336 ± 0.034	1.349LysGlu: 1.349 ± 0.033	0.858LysPhe: 0.858 ± 0.023	1.805LysGly: 1.805 ± 0.03	0.693LysHis: 0.693 ± 0.019	1.294LysIle: 1.294 ± 0.03	1.213LysLys: 1.213 ± 0.033	3.155LysLeu: 3.155 ± 0.049	0.663LysMet: 0.663 ± 0.019	0.881LysAsn: 0.881 ± 0.025	2.041LysPro: 2.041 ± 0.037	1.504LysGln: 1.504 ± 0.035	2.115LysArg: 2.115 ± 0.034	1.599LysSer: 1.599 ± 0.031	1.645LysThr: 1.645 ± 0.037	1.88LysVal: 1.88 ± 0.039	0.406LysTrp: 0.406 ± 0.017	0.726LysTyr: 0.726 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	13.887LeuAla: 13.887 ± 0.128	1.178LeuCys: 1.178 ± 0.028	5.928LeuAsp: 5.928 ± 0.06	5.559LeuGlu: 5.559 ± 0.068	3.068LeuPhe: 3.068 ± 0.039	8.335LeuGly: 8.335 ± 0.067	1.883LeuHis: 1.883 ± 0.037	3.747LeuIle: 3.747 ± 0.052	2.755LeuLys: 2.755 ± 0.041	10.625LeuLeu: 10.625 ± 0.106	1.931LeuMet: 1.931 ± 0.032	2.542LeuAsn: 2.542 ± 0.041	5.61LeuPro: 5.61 ± 0.062	2.916LeuGln: 2.916 ± 0.039	7.394LeuArg: 7.394 ± 0.073	6.014LeuSer: 6.014 ± 0.064	5.456LeuThr: 5.456 ± 0.057	7.626LeuVal: 7.626 ± 0.066	1.386LeuTrp: 1.386 ± 0.03	2.071LeuTyr: 2.071 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.263MetAla: 2.263 ± 0.035	0.176MetCys: 0.176 ± 0.01	0.859MetAsp: 0.859 ± 0.024	0.898MetGlu: 0.898 ± 0.02	0.604MetPhe: 0.604 ± 0.019	1.398MetGly: 1.398 ± 0.032	0.447MetHis: 0.447 ± 0.012	0.929MetIle: 0.929 ± 0.021	0.728MetLys: 0.728 ± 0.021	2.267MetLeu: 2.267 ± 0.039	0.41MetMet: 0.41 ± 0.013	0.655MetAsn: 0.655 ± 0.017	1.311MetPro: 1.311 ± 0.025	0.856MetGln: 0.856 ± 0.022	1.447MetArg: 1.447 ± 0.028	1.211MetSer: 1.211 ± 0.021	1.333MetThr: 1.333 ± 0.027	1.349MetVal: 1.349 ± 0.029	0.209MetTrp: 0.209 ± 0.01	0.341MetTyr: 0.341 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.902AsnAla: 2.902 ± 0.044	0.285AsnCys: 0.285 ± 0.013	1.563AsnAsp: 1.563 ± 0.035	1.333AsnGlu: 1.333 ± 0.028	0.986AsnPhe: 0.986 ± 0.033	2.585AsnGly: 2.585 ± 0.062	0.647AsnHis: 0.647 ± 0.018	1.035AsnIle: 1.035 ± 0.026	0.634AsnLys: 0.634 ± 0.019	2.717AsnLeu: 2.717 ± 0.042	0.395AsnMet: 0.395 ± 0.014	1.058AsnAsn: 1.058 ± 0.034	2.003AsnPro: 2.003 ± 0.035	1.129AsnGln: 1.129 ± 0.026	1.865AsnArg: 1.865 ± 0.034	1.454AsnSer: 1.454 ± 0.035	1.427AsnThr: 1.427 ± 0.035	1.93AsnVal: 1.93 ± 0.038	0.441AsnTrp: 0.441 ± 0.014	0.754AsnTyr: 0.754 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	7.329ProAla: 7.329 ± 0.075	0.485ProCys: 0.485 ± 0.017	3.513ProAsp: 3.513 ± 0.044	4.114ProGlu: 4.114 ± 0.051	1.826ProPhe: 1.826 ± 0.033	5.298ProGly: 5.298 ± 0.061	1.215ProHis: 1.215 ± 0.028	2.309ProIle: 2.309 ± 0.035	1.688ProLys: 1.688 ± 0.036	5.242ProLeu: 5.242 ± 0.054	1.151ProMet: 1.151 ± 0.024	1.757ProAsn: 1.757 ± 0.04	3.698ProPro: 3.698 ± 0.063	2.095ProGln: 2.095 ± 0.037	3.537ProArg: 3.537 ± 0.049	3.693ProSer: 3.693 ± 0.05	3.487ProThr: 3.487 ± 0.044	3.902ProVal: 3.902 ± 0.048	0.841ProTrp: 0.841 ± 0.02	1.208ProTyr: 1.208 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.334GlnAla: 4.334 ± 0.052	0.346GlnCys: 0.346 ± 0.014	1.524GlnAsp: 1.524 ± 0.028	1.861GlnGlu: 1.861 ± 0.036	1.209GlnPhe: 1.209 ± 0.026	2.845GlnGly: 2.845 ± 0.043	0.852GlnHis: 0.852 ± 0.022	1.563GlnIle: 1.563 ± 0.029	1.058GlnLys: 1.058 ± 0.028	3.649GlnLeu: 3.649 ± 0.051	0.821GlnMet: 0.821 ± 0.024	1.019GlnAsn: 1.019 ± 0.026	2.229GlnPro: 2.229 ± 0.038	2.185GlnGln: 2.185 ± 0.055	3.153GlnArg: 3.153 ± 0.047	2.289GlnSer: 2.289 ± 0.039	2.125GlnThr: 2.125 ± 0.034	2.65GlnVal: 2.65 ± 0.04	0.618GlnTrp: 0.618 ± 0.02	0.852GlnTyr: 0.852 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	6.624ArgAla: 6.624 ± 0.077	0.816ArgCys: 0.816 ± 0.022	4.132ArgAsp: 4.132 ± 0.046	4.021ArgGlu: 4.021 ± 0.053	2.916ArgPhe: 2.916 ± 0.044	5.511ArgGly: 5.511 ± 0.064	1.493ArgHis: 1.493 ± 0.03	3.06ArgIle: 3.06 ± 0.036	2.005ArgLys: 2.005 ± 0.038	8.423ArgLeu: 8.423 ± 0.095	1.728ArgMet: 1.728 ± 0.03	1.696ArgAsn: 1.696 ± 0.029	4.06ArgPro: 4.06 ± 0.052	2.752ArgGln: 2.752 ± 0.044	6.561ArgArg: 6.561 ± 0.085	4.202ArgSer: 4.202 ± 0.059	3.454ArgThr: 3.454 ± 0.044	5.663ArgVal: 5.663 ± 0.061	1.327ArgTrp: 1.327 ± 0.03	1.922ArgTyr: 1.922 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	6.361SerAla: 6.361 ± 0.068	0.545SerCys: 0.545 ± 0.018	3.647SerAsp: 3.647 ± 0.047	3.051SerGlu: 3.051 ± 0.041	1.969SerPhe: 1.969 ± 0.036	5.922SerGly: 5.922 ± 0.074	1.141SerHis: 1.141 ± 0.025	2.509SerIle: 2.509 ± 0.04	1.569SerLys: 1.569 ± 0.033	5.923SerLeu: 5.923 ± 0.055	1.118SerMet: 1.118 ± 0.025	1.627SerAsn: 1.627 ± 0.032	3.767SerPro: 3.767 ± 0.042	2.095SerGln: 2.095 ± 0.039	3.885SerArg: 3.885 ± 0.052	3.406SerSer: 3.406 ± 0.049	3.061SerThr: 3.061 ± 0.048	4.319SerVal: 4.319 ± 0.05	0.763SerTrp: 0.763 ± 0.021	1.305SerTyr: 1.305 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.662ThrAla: 5.662 ± 0.062	0.496ThrCys: 0.496 ± 0.017	2.972ThrAsp: 2.972 ± 0.046	2.352ThrGlu: 2.352 ± 0.042	1.812ThrPhe: 1.812 ± 0.029	5.015ThrGly: 5.015 ± 0.061	1.15ThrHis: 1.15 ± 0.027	2.469ThrIle: 2.469 ± 0.041	1.294ThrLys: 1.294 ± 0.027	5.955ThrLeu: 5.955 ± 0.067	0.899ThrMet: 0.899 ± 0.024	1.397ThrAsn: 1.397 ± 0.032	4.012ThrPro: 4.012 ± 0.054	1.843ThrGln: 1.843 ± 0.034	3.206ThrArg: 3.206 ± 0.045	2.936ThrSer: 2.936 ± 0.05	3.044ThrThr: 3.044 ± 0.059	3.76ThrVal: 3.76 ± 0.052	0.709ThrTrp: 0.709 ± 0.021	1.186ThrTyr: 1.186 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	9.127ValAla: 9.127 ± 0.076	1.002ValCys: 1.002 ± 0.026	4.811ValAsp: 4.811 ± 0.054	4.823ValGlu: 4.823 ± 0.051	2.579ValPhe: 2.579 ± 0.043	6.238ValGly: 6.238 ± 0.066	1.363ValHis: 1.363 ± 0.025	2.983ValIle: 2.983 ± 0.037	1.786ValLys: 1.786 ± 0.035	7.545ValLeu: 7.545 ± 0.07	1.493ValMet: 1.493 ± 0.032	2.063ValAsn: 2.063 ± 0.039	3.406ValPro: 3.406 ± 0.043	2.363ValGln: 2.363 ± 0.037	5.59ValArg: 5.59 ± 0.06	4.315ValSer: 4.315 ± 0.051	4.198ValThr: 4.198 ± 0.054	6.549ValVal: 6.549 ± 0.063	1.25ValTrp: 1.25 ± 0.027	1.785ValTyr: 1.785 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.319TrpAla: 1.319 ± 0.027	0.183TrpCys: 0.183 ± 0.011	0.863TrpAsp: 0.863 ± 0.02	0.743TrpGlu: 0.743 ± 0.02	0.544TrpPhe: 0.544 ± 0.018	1.172TrpGly: 1.172 ± 0.025	0.363TrpHis: 0.363 ± 0.014	0.617TrpIle: 0.617 ± 0.018	0.56TrpLys: 0.56 ± 0.019	1.787TrpLeu: 1.787 ± 0.035	0.372TrpMet: 0.372 ± 0.016	0.527TrpAsn: 0.527 ± 0.019	0.818TrpPro: 0.818 ± 0.024	0.648TrpGln: 0.648 ± 0.02	1.694TrpArg: 1.694 ± 0.031	1.01TrpSer: 1.01 ± 0.025	0.857TrpThr: 0.857 ± 0.023	1.044TrpVal: 1.044 ± 0.027	0.278TrpTrp: 0.278 ± 0.014	0.347TrpTyr: 0.347 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.623TyrAla: 2.623 ± 0.04	0.334TyrCys: 0.334 ± 0.014	1.691TyrAsp: 1.691 ± 0.031	1.356TyrGlu: 1.356 ± 0.029	1.025TyrPhe: 1.025 ± 0.023	2.116TyrGly: 2.116 ± 0.035	0.545TyrHis: 0.545 ± 0.018	0.687TyrIle: 0.687 ± 0.02	0.564TyrLys: 0.564 ± 0.017	2.424TyrLeu: 2.424 ± 0.035	0.334TyrMet: 0.334 ± 0.013	0.806TyrAsn: 0.806 ± 0.024	1.119TyrPro: 1.119 ± 0.026	0.981TyrGln: 0.981 ± 0.021	2.021TyrArg: 2.021 ± 0.028	1.267TyrSer: 1.267 ± 0.025	1.206TyrThr: 1.206 ± 0.028	1.73TyrVal: 1.73 ± 0.031	0.429TyrTrp: 0.429 ± 0.016	0.783TyrTyr: 0.783 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5103 proteins (1869859 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---