Amino acid dipepetide frequency for Acidovorax carolinensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.896AlaAla: 17.896 ± 0.198	1.316AlaCys: 1.316 ± 0.035	6.413AlaAsp: 6.413 ± 0.091	6.261AlaGlu: 6.261 ± 0.08	3.993AlaPhe: 3.993 ± 0.068	10.416AlaGly: 10.416 ± 0.118	2.981AlaHis: 2.981 ± 0.057	5.164AlaIle: 5.164 ± 0.073	4.004AlaLys: 4.004 ± 0.08	15.59AlaLeu: 15.59 ± 0.143	3.559AlaMet: 3.559 ± 0.06	2.824AlaAsn: 2.824 ± 0.049	6.642AlaPro: 6.642 ± 0.107	6.858AlaGln: 6.858 ± 0.089	8.867AlaArg: 8.867 ± 0.118	6.891AlaSer: 6.891 ± 0.089	6.636AlaThr: 6.636 ± 0.083	9.267AlaVal: 9.267 ± 0.109	1.977AlaTrp: 1.977 ± 0.045	2.357AlaTyr: 2.357 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.239CysAla: 1.239 ± 0.038	0.133CysCys: 0.133 ± 0.011	0.542CysAsp: 0.542 ± 0.025	0.469CysGlu: 0.469 ± 0.02	0.296CysPhe: 0.296 ± 0.017	0.959CysGly: 0.959 ± 0.034	0.29CysHis: 0.29 ± 0.017	0.44CysIle: 0.44 ± 0.021	0.261CysLys: 0.261 ± 0.017	0.828CysLeu: 0.828 ± 0.027	0.239CysMet: 0.239 ± 0.016	0.257CysAsn: 0.257 ± 0.016	0.55CysPro: 0.55 ± 0.026	0.294CysGln: 0.294 ± 0.017	0.533CysArg: 0.533 ± 0.025	0.513CysSer: 0.513 ± 0.025	0.556CysThr: 0.556 ± 0.025	0.677CysVal: 0.677 ± 0.027	0.113CysTrp: 0.113 ± 0.01	0.181CysTyr: 0.181 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.124AspAla: 7.124 ± 0.091	0.423AspCys: 0.423 ± 0.021	2.546AspAsp: 2.546 ± 0.059	2.996AspGlu: 2.996 ± 0.06	1.953AspPhe: 1.953 ± 0.041	4.339AspGly: 4.339 ± 0.072	1.193AspHis: 1.193 ± 0.03	2.398AspIle: 2.398 ± 0.051	1.867AspLys: 1.867 ± 0.051	5.288AspLeu: 5.288 ± 0.082	1.383AspMet: 1.383 ± 0.036	1.296AspAsn: 1.296 ± 0.036	2.679AspPro: 2.679 ± 0.048	1.606AspGln: 1.606 ± 0.041	3.147AspArg: 3.147 ± 0.069	2.31AspSer: 2.31 ± 0.043	2.593AspThr: 2.593 ± 0.05	3.984AspVal: 3.984 ± 0.066	0.868AspTrp: 0.868 ± 0.029	1.359AspTyr: 1.359 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	6.481GluAla: 6.481 ± 0.093	0.414GluCys: 0.414 ± 0.022	2.104GluAsp: 2.104 ± 0.044	2.355GluGlu: 2.355 ± 0.058	1.685GluPhe: 1.685 ± 0.044	3.735GluGly: 3.735 ± 0.066	1.33GluHis: 1.33 ± 0.038	2.516GluIle: 2.516 ± 0.059	2.026GluLys: 2.026 ± 0.049	5.645GluLeu: 5.645 ± 0.091	1.242GluMet: 1.242 ± 0.038	1.265GluAsn: 1.265 ± 0.035	2.476GluPro: 2.476 ± 0.051	2.688GluGln: 2.688 ± 0.053	4.415GluArg: 4.415 ± 0.067	2.438GluSer: 2.438 ± 0.054	2.44GluThr: 2.44 ± 0.045	3.966GluVal: 3.966 ± 0.063	0.649GluTrp: 0.649 ± 0.025	0.995GluTyr: 0.995 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.258PheAla: 4.258 ± 0.068	0.396PheCys: 0.396 ± 0.019	2.415PheAsp: 2.415 ± 0.053	1.943PheGlu: 1.943 ± 0.052	1.343PhePhe: 1.343 ± 0.04	3.164PheGly: 3.164 ± 0.057	0.72PheHis: 0.72 ± 0.024	1.46PheIle: 1.46 ± 0.036	1.241PheLys: 1.241 ± 0.035	2.895PheLeu: 2.895 ± 0.052	0.842PheMet: 0.842 ± 0.031	1.098PheAsn: 1.098 ± 0.036	1.469PhePro: 1.469 ± 0.036	1.103PheGln: 1.103 ± 0.028	1.803PheArg: 1.803 ± 0.044	2.027PheSer: 2.027 ± 0.04	1.954PheThr: 1.954 ± 0.042	2.775PheVal: 2.775 ± 0.052	0.486PheTrp: 0.486 ± 0.025	0.824PheTyr: 0.824 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	9.35GlyAla: 9.35 ± 0.121	0.87GlyCys: 0.87 ± 0.032	3.958GlyAsp: 3.958 ± 0.068	4.135GlyGlu: 4.135 ± 0.069	3.221GlyPhe: 3.221 ± 0.05	6.824GlyGly: 6.824 ± 0.123	2.023GlyHis: 2.023 ± 0.041	3.883GlyIle: 3.883 ± 0.066	3.429GlyLys: 3.429 ± 0.071	8.657GlyLeu: 8.657 ± 0.095	2.425GlyMet: 2.425 ± 0.049	2.241GlyAsn: 2.241 ± 0.055	2.977GlyPro: 2.977 ± 0.055	3.622GlyGln: 3.622 ± 0.058	5.113GlyArg: 5.113 ± 0.079	4.426GlySer: 4.426 ± 0.072	4.448GlyThr: 4.448 ± 0.074	6.529GlyVal: 6.529 ± 0.079	1.42GlyTrp: 1.42 ± 0.038	2.211GlyTyr: 2.211 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	3.065HisAla: 3.065 ± 0.064	0.341HisCys: 0.341 ± 0.019	1.257HisAsp: 1.257 ± 0.031	1.166HisGlu: 1.166 ± 0.031	0.889HisPhe: 0.889 ± 0.026	2.218HisGly: 2.218 ± 0.042	0.675HisHis: 0.675 ± 0.024	1.032HisIle: 1.032 ± 0.032	0.628HisLys: 0.628 ± 0.018	2.33HisLeu: 2.33 ± 0.046	0.555HisMet: 0.555 ± 0.024	0.551HisAsn: 0.551 ± 0.025	1.613HisPro: 1.613 ± 0.039	0.839HisGln: 0.839 ± 0.029	1.548HisArg: 1.548 ± 0.042	1.108HisSer: 1.108 ± 0.03	1.23HisThr: 1.23 ± 0.033	1.595HisVal: 1.595 ± 0.037	0.472HisTrp: 0.472 ± 0.021	0.661HisTyr: 0.661 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.115IleAla: 6.115 ± 0.073	0.408IleCys: 0.408 ± 0.02	2.952IleAsp: 2.952 ± 0.055	3.024IleGlu: 3.024 ± 0.066	1.305IlePhe: 1.305 ± 0.042	3.742IleGly: 3.742 ± 0.073	0.868IleHis: 0.868 ± 0.034	1.625IleIle: 1.625 ± 0.042	1.63IleLys: 1.63 ± 0.048	3.28IleLeu: 3.28 ± 0.058	0.77IleMet: 0.77 ± 0.029	1.459IleAsn: 1.459 ± 0.038	2.006IlePro: 2.006 ± 0.049	1.353IleGln: 1.353 ± 0.036	2.419IleArg: 2.419 ± 0.058	2.248IleSer: 2.248 ± 0.048	2.71IleThr: 2.71 ± 0.051	3.434IleVal: 3.434 ± 0.057	0.448IleTrp: 0.448 ± 0.023	0.958IleTyr: 0.958 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	4.382LysAla: 4.382 ± 0.082	0.166LysCys: 0.166 ± 0.012	1.763LysAsp: 1.763 ± 0.049	1.627LysGlu: 1.627 ± 0.043	0.969LysPhe: 0.969 ± 0.03	2.598LysGly: 2.598 ± 0.055	0.678LysHis: 0.678 ± 0.022	1.622LysIle: 1.622 ± 0.049	1.627LysLys: 1.627 ± 0.06	3.539LysLeu: 3.539 ± 0.061	0.852LysMet: 0.852 ± 0.031	1.054LysAsn: 1.054 ± 0.038	2.079LysPro: 2.079 ± 0.049	1.225LysGln: 1.225 ± 0.035	2.104LysArg: 2.104 ± 0.044	1.904LysSer: 1.904 ± 0.043	2.153LysThr: 2.153 ± 0.045	2.711LysVal: 2.711 ± 0.055	0.344LysTrp: 0.344 ± 0.02	0.678LysTyr: 0.678 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	14.864LeuAla: 14.864 ± 0.148	1.071LeuCys: 1.071 ± 0.039	5.676LeuAsp: 5.676 ± 0.073	4.942LeuGlu: 4.942 ± 0.08	3.351LeuPhe: 3.351 ± 0.067	8.549LeuGly: 8.549 ± 0.112	2.579LeuHis: 2.579 ± 0.047	4.246LeuIle: 4.246 ± 0.069	3.622LeuLys: 3.622 ± 0.07	11.158LeuLeu: 11.158 ± 0.143	2.5LeuMet: 2.5 ± 0.052	2.838LeuAsn: 2.838 ± 0.051	6.134LeuPro: 6.134 ± 0.086	5.14LeuGln: 5.14 ± 0.077	7.635LeuArg: 7.635 ± 0.102	5.842LeuSer: 5.842 ± 0.081	5.489LeuThr: 5.489 ± 0.079	8.175LeuVal: 8.175 ± 0.104	1.421LeuTrp: 1.421 ± 0.041	1.987LeuTyr: 1.987 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	3.436MetAla: 3.436 ± 0.056	0.154MetCys: 0.154 ± 0.012	1.222MetAsp: 1.222 ± 0.034	1.125MetGlu: 1.125 ± 0.034	0.676MetPhe: 0.676 ± 0.024	2.067MetGly: 2.067 ± 0.047	0.633MetHis: 0.633 ± 0.028	0.853MetIle: 0.853 ± 0.03	1.065MetLys: 1.065 ± 0.03	2.702MetLeu: 2.702 ± 0.055	0.566MetMet: 0.566 ± 0.024	0.859MetAsn: 0.859 ± 0.031	1.525MetPro: 1.525 ± 0.037	1.219MetGln: 1.219 ± 0.037	1.624MetArg: 1.624 ± 0.045	1.485MetSer: 1.485 ± 0.038	1.597MetThr: 1.597 ± 0.042	1.964MetVal: 1.964 ± 0.046	0.208MetTrp: 0.208 ± 0.014	0.392MetTyr: 0.392 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.528AsnAla: 3.528 ± 0.054	0.255AsnCys: 0.255 ± 0.015	1.335AsnAsp: 1.335 ± 0.037	1.174AsnGlu: 1.174 ± 0.034	0.986AsnPhe: 0.986 ± 0.028	2.113AsnGly: 2.113 ± 0.056	0.6AsnHis: 0.6 ± 0.024	1.219AsnIle: 1.219 ± 0.034	0.893AsnLys: 0.893 ± 0.032	2.565AsnLeu: 2.565 ± 0.045	0.613AsnMet: 0.613 ± 0.024	0.802AsnAsn: 0.802 ± 0.029	1.894AsnPro: 1.894 ± 0.046	1.003AsnGln: 1.003 ± 0.033	1.644AsnArg: 1.644 ± 0.044	1.203AsnSer: 1.203 ± 0.036	1.474AsnThr: 1.474 ± 0.043	2.008AsnVal: 2.008 ± 0.048	0.426AsnTrp: 0.426 ± 0.021	0.68AsnTyr: 0.68 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	7.22ProAla: 7.22 ± 0.108	0.392ProCys: 0.392 ± 0.02	3.164ProAsp: 3.164 ± 0.057	3.265ProGlu: 3.265 ± 0.054	1.744ProPhe: 1.744 ± 0.04	4.717ProGly: 4.717 ± 0.076	1.281ProHis: 1.281 ± 0.036	1.826ProIle: 1.826 ± 0.042	1.552ProLys: 1.552 ± 0.039	5.466ProLeu: 5.466 ± 0.077	1.329ProMet: 1.329 ± 0.039	1.187ProAsn: 1.187 ± 0.035	2.68ProPro: 2.68 ± 0.065	2.399ProGln: 2.399 ± 0.05	2.811ProArg: 2.811 ± 0.058	2.661ProSer: 2.661 ± 0.045	2.706ProThr: 2.706 ± 0.048	4.455ProVal: 4.455 ± 0.072	0.81ProTrp: 0.81 ± 0.027	1.158ProTyr: 1.158 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	6.122GlnAla: 6.122 ± 0.095	0.37GlnCys: 0.37 ± 0.02	1.845GlnAsp: 1.845 ± 0.043	1.862GlnGlu: 1.862 ± 0.044	1.44GlnPhe: 1.44 ± 0.033	3.455GlnGly: 3.455 ± 0.051	1.099GlnHis: 1.099 ± 0.032	1.897GlnIle: 1.897 ± 0.04	1.311GlnLys: 1.311 ± 0.036	4.625GlnLeu: 4.625 ± 0.061	1.11GlnMet: 1.11 ± 0.034	1.016GlnAsn: 1.016 ± 0.03	2.592GlnPro: 2.592 ± 0.048	2.228GlnGln: 2.228 ± 0.051	3.815GlnArg: 3.815 ± 0.077	2.234GlnSer: 2.234 ± 0.049	2.075GlnThr: 2.075 ± 0.043	3.284GlnVal: 3.284 ± 0.055	0.778GlnTrp: 0.778 ± 0.029	0.812GlnTyr: 0.812 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	7.627ArgAla: 7.627 ± 0.086	0.593ArgCys: 0.593 ± 0.026	3.333ArgAsp: 3.333 ± 0.06	3.906ArgGlu: 3.906 ± 0.064	2.629ArgPhe: 2.629 ± 0.051	4.386ArgGly: 4.386 ± 0.073	1.836ArgHis: 1.836 ± 0.044	3.315ArgIle: 3.315 ± 0.054	2.193ArgLys: 2.193 ± 0.043	7.557ArgLeu: 7.557 ± 0.098	1.933ArgMet: 1.933 ± 0.046	1.903ArgAsn: 1.903 ± 0.043	3.154ArgPro: 3.154 ± 0.061	3.064ArgGln: 3.064 ± 0.058	4.698ArgArg: 4.698 ± 0.075	3.48ArgSer: 3.48 ± 0.059	3.32ArgThr: 3.32 ± 0.057	4.89ArgVal: 4.89 ± 0.07	1.209ArgTrp: 1.209 ± 0.032	1.682ArgTyr: 1.682 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.615SerAla: 6.615 ± 0.092	0.461SerCys: 0.461 ± 0.024	2.528SerAsp: 2.528 ± 0.056	2.435SerGlu: 2.435 ± 0.049	1.952SerPhe: 1.952 ± 0.045	4.937SerGly: 4.937 ± 0.073	1.27SerHis: 1.27 ± 0.036	2.335SerIle: 2.335 ± 0.057	1.587SerLys: 1.587 ± 0.046	5.457SerLeu: 5.457 ± 0.073	1.378SerMet: 1.378 ± 0.041	1.376SerAsn: 1.376 ± 0.037	2.871SerPro: 2.871 ± 0.054	1.994SerGln: 1.994 ± 0.047	3.34SerArg: 3.34 ± 0.06	2.945SerSer: 2.945 ± 0.062	2.989SerThr: 2.989 ± 0.052	4.046SerVal: 4.046 ± 0.053	0.687SerTrp: 0.687 ± 0.028	1.19SerTyr: 1.19 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	6.492ThrAla: 6.492 ± 0.079	0.408ThrCys: 0.408 ± 0.023	2.604ThrAsp: 2.604 ± 0.053	2.563ThrGlu: 2.563 ± 0.051	1.626ThrPhe: 1.626 ± 0.039	4.834ThrGly: 4.834 ± 0.075	1.26ThrHis: 1.26 ± 0.041	2.202ThrIle: 2.202 ± 0.042	1.397ThrLys: 1.397 ± 0.043	6.452ThrLeu: 6.452 ± 0.095	1.183ThrMet: 1.183 ± 0.038	1.284ThrAsn: 1.284 ± 0.039	3.604ThrPro: 3.604 ± 0.062	2.249ThrGln: 2.249 ± 0.044	3.191ThrArg: 3.191 ± 0.058	2.797ThrSer: 2.797 ± 0.058	3.039ThrThr: 3.039 ± 0.071	4.412ThrVal: 4.412 ± 0.064	0.662ThrTrp: 0.662 ± 0.024	1.055ThrTyr: 1.055 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	10.012ValAla: 10.012 ± 0.1	0.746ValCys: 0.746 ± 0.029	3.925ValAsp: 3.925 ± 0.055	3.977ValGlu: 3.977 ± 0.062	2.723ValPhe: 2.723 ± 0.056	5.843ValGly: 5.843 ± 0.084	1.666ValHis: 1.666 ± 0.041	3.3ValIle: 3.3 ± 0.067	2.542ValLys: 2.542 ± 0.052	8.618ValLeu: 8.618 ± 0.093	2.01ValMet: 2.01 ± 0.046	2.109ValAsn: 2.109 ± 0.046	4.091ValPro: 4.091 ± 0.066	3.417ValGln: 3.417 ± 0.053	5.231ValArg: 5.231 ± 0.078	3.925ValSer: 3.925 ± 0.065	3.99ValThr: 3.99 ± 0.068	6.768ValVal: 6.768 ± 0.092	1.011ValTrp: 1.011 ± 0.033	1.578ValTyr: 1.578 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.503TrpAla: 1.503 ± 0.038	0.198TrpCys: 0.198 ± 0.015	0.605TrpAsp: 0.605 ± 0.024	0.538TrpGlu: 0.538 ± 0.02	0.545TrpPhe: 0.545 ± 0.023	0.977TrpGly: 0.977 ± 0.031	0.349TrpHis: 0.349 ± 0.019	0.627TrpIle: 0.627 ± 0.026	0.491TrpLys: 0.491 ± 0.02	2.179TrpLeu: 2.179 ± 0.05	0.482TrpMet: 0.482 ± 0.02	0.394TrpAsn: 0.394 ± 0.019	0.733TrpPro: 0.733 ± 0.028	0.781TrpGln: 0.781 ± 0.028	1.17TrpArg: 1.17 ± 0.039	0.771TrpSer: 0.771 ± 0.028	0.708TrpThr: 0.708 ± 0.026	1.029TrpVal: 1.029 ± 0.034	0.294TrpTrp: 0.294 ± 0.017	0.272TrpTyr: 0.272 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.582TyrAla: 2.582 ± 0.047	0.254TyrCys: 0.254 ± 0.016	1.162TyrAsp: 1.162 ± 0.034	1.104TyrGlu: 1.104 ± 0.03	0.891TyrPhe: 0.891 ± 0.028	1.887TyrGly: 1.887 ± 0.043	0.442TyrHis: 0.442 ± 0.019	0.792TyrIle: 0.792 ± 0.025	0.709TyrLys: 0.709 ± 0.029	2.392TyrLeu: 2.392 ± 0.05	0.402TyrMet: 0.402 ± 0.019	0.602TyrAsn: 0.602 ± 0.026	1.054TyrPro: 1.054 ± 0.033	0.889TyrGln: 0.889 ± 0.03	1.598TyrArg: 1.598 ± 0.04	1.184TyrSer: 1.184 ± 0.035	1.208TyrThr: 1.208 ± 0.037	1.516TyrVal: 1.516 ± 0.04	0.36TyrTrp: 0.36 ± 0.018	0.549TyrTyr: 0.549 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3397 proteins (1079858 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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