Amino acid dipepetide frequency for Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.107AlaAla: 19.107 ± 0.173	1.41AlaCys: 1.41 ± 0.034	7.241AlaAsp: 7.241 ± 0.085	6.638AlaGlu: 6.638 ± 0.087	4.161AlaPhe: 4.161 ± 0.055	11.827AlaGly: 11.827 ± 0.126	2.908AlaHis: 2.908 ± 0.05	5.565AlaIle: 5.565 ± 0.057	3.305AlaLys: 3.305 ± 0.056	14.814AlaLeu: 14.814 ± 0.14	3.592AlaMet: 3.592 ± 0.051	3.156AlaAsn: 3.156 ± 0.066	6.785AlaPro: 6.785 ± 0.104	5.94AlaGln: 5.94 ± 0.075	9.914AlaArg: 9.914 ± 0.118	7.13AlaSer: 7.13 ± 0.076	6.57AlaThr: 6.57 ± 0.094	9.28AlaVal: 9.28 ± 0.083	1.931AlaTrp: 1.931 ± 0.042	2.865AlaTyr: 2.865 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.305CysAla: 1.305 ± 0.032	0.117CysCys: 0.117 ± 0.01	0.515CysAsp: 0.515 ± 0.018	0.483CysGlu: 0.483 ± 0.019	0.328CysPhe: 0.328 ± 0.015	1.01CysGly: 1.01 ± 0.026	0.264CysHis: 0.264 ± 0.014	0.378CysIle: 0.378 ± 0.016	0.227CysLys: 0.227 ± 0.01	0.844CysLeu: 0.844 ± 0.024	0.192CysMet: 0.192 ± 0.01	0.249CysAsn: 0.249 ± 0.013	0.515CysPro: 0.515 ± 0.021	0.256CysGln: 0.256 ± 0.011	0.669CysArg: 0.669 ± 0.024	0.496CysSer: 0.496 ± 0.017	0.464CysThr: 0.464 ± 0.018	0.71CysVal: 0.71 ± 0.022	0.121CysTrp: 0.121 ± 0.009	0.212CysTyr: 0.212 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.152AspAla: 8.152 ± 0.092	0.495AspCys: 0.495 ± 0.022	2.982AspAsp: 2.982 ± 0.048	2.774AspGlu: 2.774 ± 0.058	1.857AspPhe: 1.857 ± 0.037	4.822AspGly: 4.822 ± 0.073	1.185AspHis: 1.185 ± 0.03	2.456AspIle: 2.456 ± 0.041	1.608AspLys: 1.608 ± 0.037	5.089AspLeu: 5.089 ± 0.06	1.179AspMet: 1.179 ± 0.026	1.342AspAsn: 1.342 ± 0.028	3.116AspPro: 3.116 ± 0.052	1.595AspGln: 1.595 ± 0.034	3.598AspArg: 3.598 ± 0.053	2.242AspSer: 2.242 ± 0.042	3.061AspThr: 3.061 ± 0.057	4.105AspVal: 4.105 ± 0.05	0.956AspTrp: 0.956 ± 0.025	1.411AspTyr: 1.411 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	7.172GluAla: 7.172 ± 0.096	0.392GluCys: 0.392 ± 0.015	2.187GluAsp: 2.187 ± 0.039	2.019GluGlu: 2.019 ± 0.042	1.467GluPhe: 1.467 ± 0.033	3.395GluGly: 3.395 ± 0.057	1.41GluHis: 1.41 ± 0.032	2.504GluIle: 2.504 ± 0.038	1.459GluLys: 1.459 ± 0.037	4.877GluLeu: 4.877 ± 0.066	1.124GluMet: 1.124 ± 0.031	1.145GluAsn: 1.145 ± 0.027	2.473GluPro: 2.473 ± 0.045	2.505GluGln: 2.505 ± 0.049	4.677GluArg: 4.677 ± 0.069	2.289GluSer: 2.289 ± 0.044	2.678GluThr: 2.678 ± 0.045	3.473GluVal: 3.473 ± 0.058	0.677GluTrp: 0.677 ± 0.02	1.053GluTyr: 1.053 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.206PheAla: 4.206 ± 0.057	0.398PheCys: 0.398 ± 0.017	2.419PheAsp: 2.419 ± 0.039	1.786PheGlu: 1.786 ± 0.041	1.283PhePhe: 1.283 ± 0.035	3.328PheGly: 3.328 ± 0.053	0.773PheHis: 0.773 ± 0.021	1.425PheIle: 1.425 ± 0.034	0.992PheLys: 0.992 ± 0.026	2.851PheLeu: 2.851 ± 0.048	0.681PheMet: 0.681 ± 0.02	1.066PheAsn: 1.066 ± 0.03	1.48PhePro: 1.48 ± 0.029	0.991PheGln: 0.991 ± 0.027	2.035PheArg: 2.035 ± 0.036	2.109PheSer: 2.109 ± 0.036	1.819PheThr: 1.819 ± 0.046	2.699PheVal: 2.699 ± 0.044	0.487PheTrp: 0.487 ± 0.015	0.847PheTyr: 0.847 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.903GlyAla: 9.903 ± 0.107	0.911GlyCys: 0.911 ± 0.023	4.056GlyAsp: 4.056 ± 0.057	4.165GlyGlu: 4.165 ± 0.055	3.106GlyPhe: 3.106 ± 0.055	7.211GlyGly: 7.211 ± 0.132	1.975GlyHis: 1.975 ± 0.038	4.034GlyIle: 4.034 ± 0.059	3.176GlyLys: 3.176 ± 0.055	8.388GlyLeu: 8.388 ± 0.083	2.333GlyMet: 2.333 ± 0.037	2.731GlyAsn: 2.731 ± 0.092	3.087GlyPro: 3.087 ± 0.049	3.259GlyGln: 3.259 ± 0.054	5.679GlyArg: 5.679 ± 0.061	4.566GlySer: 4.566 ± 0.1	5.267GlyThr: 5.267 ± 0.131	6.393GlyVal: 6.393 ± 0.072	1.425GlyTrp: 1.425 ± 0.037	2.394GlyTyr: 2.394 ± 0.033	0.0GlyXaa: 0.0 ± 0.0
His	3.417HisAla: 3.417 ± 0.056	0.283HisCys: 0.283 ± 0.013	1.355HisAsp: 1.355 ± 0.033	1.07HisGlu: 1.07 ± 0.027	0.89HisPhe: 0.89 ± 0.025	2.217HisGly: 2.217 ± 0.04	0.652HisHis: 0.652 ± 0.025	0.891HisIle: 0.891 ± 0.022	0.5HisLys: 0.5 ± 0.016	2.216HisLeu: 2.216 ± 0.039	0.48HisMet: 0.48 ± 0.018	0.482HisAsn: 0.482 ± 0.019	1.62HisPro: 1.62 ± 0.037	0.743HisGln: 0.743 ± 0.021	1.651HisArg: 1.651 ± 0.039	0.977HisSer: 0.977 ± 0.029	1.085HisThr: 1.085 ± 0.026	1.652HisVal: 1.652 ± 0.033	0.397HisTrp: 0.397 ± 0.017	0.654HisTyr: 0.654 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.343IleAla: 6.343 ± 0.073	0.404IleCys: 0.404 ± 0.017	3.292IleAsp: 3.292 ± 0.047	2.899IleGlu: 2.899 ± 0.049	1.168IlePhe: 1.168 ± 0.031	4.537IleGly: 4.537 ± 0.061	0.864IleHis: 0.864 ± 0.022	1.449IleIle: 1.449 ± 0.037	1.315IleLys: 1.315 ± 0.031	3.416IleLeu: 3.416 ± 0.05	0.659IleMet: 0.659 ± 0.022	1.364IleAsn: 1.364 ± 0.036	2.03IlePro: 2.03 ± 0.036	1.289IleGln: 1.289 ± 0.03	2.888IleArg: 2.888 ± 0.048	2.189IleSer: 2.189 ± 0.045	2.408IleThr: 2.408 ± 0.047	3.65IleVal: 3.65 ± 0.06	0.461IleTrp: 0.461 ± 0.018	0.945IleTyr: 0.945 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	3.413LysAla: 3.413 ± 0.055	0.148LysCys: 0.148 ± 0.011	1.422LysAsp: 1.422 ± 0.034	1.247LysGlu: 1.247 ± 0.031	0.752LysPhe: 0.752 ± 0.025	2.096LysGly: 2.096 ± 0.034	0.654LysHis: 0.654 ± 0.021	1.303LysIle: 1.303 ± 0.034	1.098LysLys: 1.098 ± 0.039	3.114LysLeu: 3.114 ± 0.056	0.684LysMet: 0.684 ± 0.023	0.8LysAsn: 0.8 ± 0.027	1.886LysPro: 1.886 ± 0.042	1.223LysGln: 1.223 ± 0.031	2.216LysArg: 2.216 ± 0.043	1.455LysSer: 1.455 ± 0.039	1.814LysThr: 1.814 ± 0.041	2.101LysVal: 2.101 ± 0.05	0.375LysTrp: 0.375 ± 0.024	0.63LysTyr: 0.63 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	14.685LeuAla: 14.685 ± 0.134	1.028LeuCys: 1.028 ± 0.027	5.767LeuAsp: 5.767 ± 0.068	4.881LeuGlu: 4.881 ± 0.072	3.413LeuPhe: 3.413 ± 0.056	8.156LeuGly: 8.156 ± 0.082	2.282LeuHis: 2.282 ± 0.042	4.208LeuIle: 4.208 ± 0.059	3.047LeuLys: 3.047 ± 0.06	10.348LeuLeu: 10.348 ± 0.127	2.26LeuMet: 2.26 ± 0.045	2.69LeuAsn: 2.69 ± 0.051	6.114LeuPro: 6.114 ± 0.081	3.746LeuGln: 3.746 ± 0.058	7.794LeuArg: 7.794 ± 0.086	6.381LeuSer: 6.381 ± 0.075	5.767LeuThr: 5.767 ± 0.082	7.08LeuVal: 7.08 ± 0.076	1.186LeuTrp: 1.186 ± 0.028	2.217LeuTyr: 2.217 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.857MetAla: 2.857 ± 0.049	0.162MetCys: 0.162 ± 0.009	0.988MetAsp: 0.988 ± 0.027	1.003MetGlu: 1.003 ± 0.031	0.67MetPhe: 0.67 ± 0.02	1.629MetGly: 1.629 ± 0.037	0.549MetHis: 0.549 ± 0.018	0.935MetIle: 0.935 ± 0.027	0.815MetLys: 0.815 ± 0.027	2.645MetLeu: 2.645 ± 0.044	0.586MetMet: 0.586 ± 0.019	0.707MetAsn: 0.707 ± 0.024	1.587MetPro: 1.587 ± 0.031	1.057MetGln: 1.057 ± 0.027	1.868MetArg: 1.868 ± 0.036	1.443MetSer: 1.443 ± 0.033	1.661MetThr: 1.661 ± 0.032	1.596MetVal: 1.596 ± 0.03	0.214MetTrp: 0.214 ± 0.012	0.348MetTyr: 0.348 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.652AsnAla: 3.652 ± 0.075	0.262AsnCys: 0.262 ± 0.015	1.422AsnAsp: 1.422 ± 0.045	1.069AsnGlu: 1.069 ± 0.022	0.804AsnPhe: 0.804 ± 0.022	2.551AsnGly: 2.551 ± 0.059	0.534AsnHis: 0.534 ± 0.018	1.178AsnIle: 1.178 ± 0.03	0.699AsnLys: 0.699 ± 0.026	2.737AsnLeu: 2.737 ± 0.052	0.515AsnMet: 0.515 ± 0.018	0.798AsnAsn: 0.798 ± 0.033	1.81AsnPro: 1.81 ± 0.036	0.93AsnGln: 0.93 ± 0.027	1.834AsnArg: 1.834 ± 0.034	1.213AsnSer: 1.213 ± 0.044	1.607AsnThr: 1.607 ± 0.048	2.175AsnVal: 2.175 ± 0.059	0.425AsnTrp: 0.425 ± 0.021	0.677AsnTyr: 0.677 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	7.931ProAla: 7.931 ± 0.087	0.394ProCys: 0.394 ± 0.016	3.464ProAsp: 3.464 ± 0.052	3.208ProGlu: 3.208 ± 0.044	1.802ProPhe: 1.802 ± 0.037	4.567ProGly: 4.567 ± 0.059	1.255ProHis: 1.255 ± 0.034	2.052ProIle: 2.052 ± 0.033	1.409ProLys: 1.409 ± 0.031	5.159ProLeu: 5.159 ± 0.07	1.246ProMet: 1.246 ± 0.028	1.392ProAsn: 1.392 ± 0.03	2.811ProPro: 2.811 ± 0.066	2.044ProGln: 2.044 ± 0.036	3.2ProArg: 3.2 ± 0.058	2.92ProSer: 2.92 ± 0.047	2.78ProThr: 2.78 ± 0.063	4.362ProVal: 4.362 ± 0.063	0.705ProTrp: 0.705 ± 0.024	1.222ProTyr: 1.222 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	5.745GlnAla: 5.745 ± 0.083	0.312GlnCys: 0.312 ± 0.014	1.645GlnAsp: 1.645 ± 0.034	1.457GlnGlu: 1.457 ± 0.033	1.202GlnPhe: 1.202 ± 0.025	2.916GlnGly: 2.916 ± 0.055	0.982GlnHis: 0.982 ± 0.027	1.851GlnIle: 1.851 ± 0.039	1.027GlnLys: 1.027 ± 0.025	3.868GlnLeu: 3.868 ± 0.049	0.935GlnMet: 0.935 ± 0.021	0.932GlnAsn: 0.932 ± 0.032	2.407GlnPro: 2.407 ± 0.041	1.91GlnGln: 1.91 ± 0.042	3.221GlnArg: 3.221 ± 0.05	2.071GlnSer: 2.071 ± 0.04	2.178GlnThr: 2.178 ± 0.044	2.74GlnVal: 2.74 ± 0.046	0.618GlnTrp: 0.618 ± 0.018	0.939GlnTyr: 0.939 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	8.998ArgAla: 8.998 ± 0.106	0.636ArgCys: 0.636 ± 0.021	3.852ArgAsp: 3.852 ± 0.057	4.11ArgGlu: 4.11 ± 0.059	2.895ArgPhe: 2.895 ± 0.054	4.766ArgGly: 4.766 ± 0.06	2.012ArgHis: 2.012 ± 0.04	3.724ArgIle: 3.724 ± 0.053	2.028ArgLys: 2.028 ± 0.042	8.027ArgLeu: 8.027 ± 0.092	1.912ArgMet: 1.912 ± 0.033	1.94ArgAsn: 1.94 ± 0.036	3.512ArgPro: 3.512 ± 0.059	3.153ArgGln: 3.153 ± 0.052	5.629ArgArg: 5.629 ± 0.086	3.333ArgSer: 3.333 ± 0.047	3.667ArgThr: 3.667 ± 0.05	5.353ArgVal: 5.353 ± 0.07	1.213ArgTrp: 1.213 ± 0.029	2.084ArgTyr: 2.084 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.89SerAla: 6.89 ± 0.084	0.404SerCys: 0.404 ± 0.017	2.578SerAsp: 2.578 ± 0.047	2.254SerGlu: 2.254 ± 0.036	1.812SerPhe: 1.812 ± 0.035	5.329SerGly: 5.329 ± 0.1	1.188SerHis: 1.188 ± 0.032	2.433SerIle: 2.433 ± 0.042	1.413SerLys: 1.413 ± 0.037	5.475SerLeu: 5.475 ± 0.076	1.263SerMet: 1.263 ± 0.031	1.505SerAsn: 1.505 ± 0.042	2.941SerPro: 2.941 ± 0.052	1.917SerGln: 1.917 ± 0.04	3.603SerArg: 3.603 ± 0.048	3.036SerSer: 3.036 ± 0.077	3.162SerThr: 3.162 ± 0.084	4.098SerVal: 4.098 ± 0.058	0.65SerTrp: 0.65 ± 0.021	1.231SerTyr: 1.231 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	6.725ThrAla: 6.725 ± 0.15	0.444ThrCys: 0.444 ± 0.016	2.863ThrAsp: 2.863 ± 0.06	2.366ThrGlu: 2.366 ± 0.045	1.852ThrPhe: 1.852 ± 0.037	5.089ThrGly: 5.089 ± 0.093	1.285ThrHis: 1.285 ± 0.027	2.36ThrIle: 2.36 ± 0.052	1.101ThrLys: 1.101 ± 0.029	6.908ThrLeu: 6.908 ± 0.081	1.104ThrMet: 1.104 ± 0.029	1.355ThrAsn: 1.355 ± 0.05	3.635ThrPro: 3.635 ± 0.066	2.089ThrGln: 2.089 ± 0.041	3.625ThrArg: 3.625 ± 0.049	2.839ThrSer: 2.839 ± 0.06	3.204ThrThr: 3.204 ± 0.111	4.763ThrVal: 4.763 ± 0.085	0.693ThrTrp: 0.693 ± 0.02	1.336ThrTyr: 1.336 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	9.473ValAla: 9.473 ± 0.09	0.759ValCys: 0.759 ± 0.022	3.95ValAsp: 3.95 ± 0.053	3.914ValGlu: 3.914 ± 0.059	2.747ValPhe: 2.747 ± 0.045	5.57ValGly: 5.57 ± 0.063	1.522ValHis: 1.522 ± 0.033	3.324ValIle: 3.324 ± 0.058	2.139ValLys: 2.139 ± 0.043	7.877ValLeu: 7.877 ± 0.083	1.764ValMet: 1.764 ± 0.039	2.126ValAsn: 2.126 ± 0.045	4.225ValPro: 4.225 ± 0.054	2.61ValGln: 2.61 ± 0.046	5.488ValArg: 5.488 ± 0.076	4.493ValSer: 4.493 ± 0.071	4.409ValThr: 4.409 ± 0.076	6.078ValVal: 6.078 ± 0.076	0.946ValTrp: 0.946 ± 0.025	1.574ValTyr: 1.574 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.248TrpAla: 1.248 ± 0.033	0.164TrpCys: 0.164 ± 0.011	0.587TrpAsp: 0.587 ± 0.019	0.539TrpGlu: 0.539 ± 0.018	0.571TrpPhe: 0.571 ± 0.019	0.912TrpGly: 0.912 ± 0.027	0.433TrpHis: 0.433 ± 0.016	0.683TrpIle: 0.683 ± 0.024	0.447TrpLys: 0.447 ± 0.018	1.973TrpLeu: 1.973 ± 0.043	0.408TrpMet: 0.408 ± 0.015	0.437TrpAsn: 0.437 ± 0.015	0.711TrpPro: 0.711 ± 0.025	0.77TrpGln: 0.77 ± 0.024	1.254TrpArg: 1.254 ± 0.032	0.816TrpSer: 0.816 ± 0.022	0.708TrpThr: 0.708 ± 0.026	0.9TrpVal: 0.9 ± 0.027	0.259TrpTrp: 0.259 ± 0.014	0.304TrpTyr: 0.304 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.916TyrAla: 2.916 ± 0.048	0.233TyrCys: 0.233 ± 0.011	1.443TyrAsp: 1.443 ± 0.04	1.093TyrGlu: 1.093 ± 0.025	0.896TyrPhe: 0.896 ± 0.027	2.13TyrGly: 2.13 ± 0.042	0.503TyrHis: 0.503 ± 0.017	0.817TyrIle: 0.817 ± 0.023	0.626TyrLys: 0.626 ± 0.021	2.421TyrLeu: 2.421 ± 0.041	0.401TyrMet: 0.401 ± 0.017	0.675TyrAsn: 0.675 ± 0.02	1.179TyrPro: 1.179 ± 0.03	0.927TyrGln: 0.927 ± 0.027	2.0TyrArg: 2.0 ± 0.035	1.186TyrSer: 1.186 ± 0.033	1.33TyrThr: 1.33 ± 0.037	1.779TyrVal: 1.779 ± 0.034	0.388TyrTrp: 0.388 ± 0.016	0.67TyrTyr: 0.67 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5002 proteins (1662664 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---