Simian immunodeficiency virus (isolate EK505) (SIV-cpz) (Chimpanzee immunodeficiency virus)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Simian immunodeficiency virus; Simian immunodeficiency virus - cpz

Average proteome isoelectric point is 7.42

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|Q1A245|REV_SIVEK Protein Rev OS=Simian immunodeficiency virus (isolate EK505) OX=388912 GN=rev PE=3 SV=1
MM1 pKa = 7.62LLLIKK6 pKa = 10.64LGFIGLAIEE15 pKa = 4.03TLIVIVVWAIVYY27 pKa = 9.82RR28 pKa = 11.84IYY30 pKa = 11.02RR31 pKa = 11.84EE32 pKa = 3.96VKK34 pKa = 8.82VEE36 pKa = 4.0EE37 pKa = 5.16KK38 pKa = 10.32ISQLRR43 pKa = 11.84QRR45 pKa = 11.84IRR47 pKa = 11.84DD48 pKa = 3.56RR49 pKa = 11.84AEE51 pKa = 4.07DD52 pKa = 3.62SGNEE56 pKa = 3.89SDD58 pKa = 5.71GDD60 pKa = 4.02AEE62 pKa = 4.16EE63 pKa = 4.73LANLLPPDD71 pKa = 5.9RR72 pKa = 11.84IDD74 pKa = 3.21QDD76 pKa = 3.08NWVV79 pKa = 3.52

Molecular weight:
9.14 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|Q1A246|TAT_SIVEK Protein Tat OS=Simian immunodeficiency virus (isolate EK505) OX=388912 GN=tat PE=3 SV=1
MM1 pKa = 7.78AGRR4 pKa = 11.84SGVNDD9 pKa = 3.64EE10 pKa = 4.36EE11 pKa = 4.38LLRR14 pKa = 11.84AIRR17 pKa = 11.84VIKK20 pKa = 10.18ILYY23 pKa = 8.97QSNPYY28 pKa = 9.86PNDD31 pKa = 3.19SGTRR35 pKa = 11.84QARR38 pKa = 11.84KK39 pKa = 8.34NRR41 pKa = 11.84RR42 pKa = 11.84RR43 pKa = 11.84RR44 pKa = 11.84WRR46 pKa = 11.84ARR48 pKa = 11.84QRR50 pKa = 11.84QIRR53 pKa = 11.84ALSEE57 pKa = 4.76RR58 pKa = 11.84ILSSCVGGLQEE69 pKa = 5.31PSTLPLPPLDD79 pKa = 3.83RR80 pKa = 11.84LSLNPEE86 pKa = 3.77EE87 pKa = 5.36DD88 pKa = 3.41LGTSEE93 pKa = 4.65TEE95 pKa = 4.26HH96 pKa = 6.28PQGTATTT103 pKa = 4.06

Molecular weight:
11.65 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

3562

79

1448

395.8

44.84

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.345 ± 0.698

1.965 ± 0.337

3.734 ± 0.364

7.103 ± 0.752

2.442 ± 0.255

7.383 ± 0.228

2.021 ± 0.462

6.541 ± 1.007

6.429 ± 1.015

8.703 ± 0.611

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.302 ± 0.306

5.053 ± 0.766

5.503 ± 0.545

6.176 ± 0.167

5.924 ± 0.824

4.66 ± 0.473

6.092 ± 0.555

6.12 ± 0.418

2.695 ± 0.281

2.807 ± 0.22

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski