Amino acid dipepetide frequency for Phycisphaera sp.

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.908AlaAla: 10.908 ± 0.15	1.231AlaCys: 1.231 ± 0.03	6.648AlaAsp: 6.648 ± 0.094	7.208AlaGlu: 7.208 ± 0.106	3.565AlaPhe: 3.565 ± 0.065	9.166AlaGly: 9.166 ± 0.114	1.863AlaHis: 1.863 ± 0.045	5.797AlaIle: 5.797 ± 0.078	3.604AlaLys: 3.604 ± 0.076	9.223AlaLeu: 9.223 ± 0.117	2.936AlaMet: 2.936 ± 0.067	2.703AlaAsn: 2.703 ± 0.057	3.963AlaPro: 3.963 ± 0.07	3.615AlaGln: 3.615 ± 0.069	6.357AlaArg: 6.357 ± 0.098	7.059AlaSer: 7.059 ± 0.09	5.079AlaThr: 5.079 ± 0.088	7.542AlaVal: 7.542 ± 0.104	1.544AlaTrp: 1.544 ± 0.039	2.172AlaTyr: 2.172 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.024CysAla: 1.024 ± 0.034	0.188CysCys: 0.188 ± 0.017	0.783CysAsp: 0.783 ± 0.033	0.65CysGlu: 0.65 ± 0.029	0.355CysPhe: 0.355 ± 0.018	0.892CysGly: 0.892 ± 0.036	0.265CysHis: 0.265 ± 0.021	0.505CysIle: 0.505 ± 0.023	0.36CysLys: 0.36 ± 0.017	0.845CysLeu: 0.845 ± 0.031	0.264CysMet: 0.264 ± 0.015	0.286CysAsn: 0.286 ± 0.018	0.62CysPro: 0.62 ± 0.027	0.275CysGln: 0.275 ± 0.017	0.633CysArg: 0.633 ± 0.031	0.637CysSer: 0.637 ± 0.027	0.608CysThr: 0.608 ± 0.025	0.778CysVal: 0.778 ± 0.029	0.14CysTrp: 0.14 ± 0.012	0.222CysTyr: 0.222 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.828AspAla: 6.828 ± 0.101	0.531AspCys: 0.531 ± 0.024	4.356AspAsp: 4.356 ± 0.097	5.139AspGlu: 5.139 ± 0.082	2.379AspPhe: 2.379 ± 0.062	5.646AspGly: 5.646 ± 0.132	1.397AspHis: 1.397 ± 0.04	3.325AspIle: 3.325 ± 0.064	1.832AspLys: 1.832 ± 0.054	5.958AspLeu: 5.958 ± 0.082	1.287AspMet: 1.287 ± 0.037	1.895AspAsn: 1.895 ± 0.051	4.059AspPro: 4.059 ± 0.069	2.306AspGln: 2.306 ± 0.053	4.584AspArg: 4.584 ± 0.072	3.844AspSer: 3.844 ± 0.087	3.402AspThr: 3.402 ± 0.069	4.461AspVal: 4.461 ± 0.076	0.901AspTrp: 0.901 ± 0.034	1.478AspTyr: 1.478 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.751GluAla: 6.751 ± 0.103	0.597GluCys: 0.597 ± 0.027	3.486GluAsp: 3.486 ± 0.067	3.91GluGlu: 3.91 ± 0.08	2.254GluPhe: 2.254 ± 0.048	4.669GluGly: 4.669 ± 0.074	1.785GluHis: 1.785 ± 0.046	4.072GluIle: 4.072 ± 0.076	2.116GluLys: 2.116 ± 0.054	7.039GluLeu: 7.039 ± 0.089	1.679GluMet: 1.679 ± 0.042	1.897GluAsn: 1.897 ± 0.048	3.446GluPro: 3.446 ± 0.069	3.061GluGln: 3.061 ± 0.056	5.049GluArg: 5.049 ± 0.098	4.722GluSer: 4.722 ± 0.074	3.639GluThr: 3.639 ± 0.067	4.157GluVal: 4.157 ± 0.069	0.733GluTrp: 0.733 ± 0.027	1.481GluTyr: 1.481 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	3.427PheAla: 3.427 ± 0.066	0.35PheCys: 0.35 ± 0.021	2.935PheAsp: 2.935 ± 0.066	2.579PheGlu: 2.579 ± 0.05	1.283PhePhe: 1.283 ± 0.042	3.612PheGly: 3.612 ± 0.062	0.593PheHis: 0.593 ± 0.022	1.704PheIle: 1.704 ± 0.05	1.054PheLys: 1.054 ± 0.039	2.624PheLeu: 2.624 ± 0.058	0.732PheMet: 0.732 ± 0.027	1.31PheAsn: 1.31 ± 0.042	1.359PhePro: 1.359 ± 0.037	0.914PheGln: 0.914 ± 0.03	1.899PheArg: 1.899 ± 0.045	2.1PheSer: 2.1 ± 0.048	2.279PheThr: 2.279 ± 0.059	2.871PheVal: 2.871 ± 0.061	0.481PheTrp: 0.481 ± 0.022	0.854PheTyr: 0.854 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	7.548GlyAla: 7.548 ± 0.101	1.138GlyCys: 1.138 ± 0.036	5.729GlyAsp: 5.729 ± 0.124	5.429GlyGlu: 5.429 ± 0.085	3.312GlyPhe: 3.312 ± 0.057	7.228GlyGly: 7.228 ± 0.136	1.621GlyHis: 1.621 ± 0.044	4.333GlyIle: 4.333 ± 0.069	3.281GlyLys: 3.281 ± 0.071	7.772GlyLeu: 7.772 ± 0.097	2.3GlyMet: 2.3 ± 0.057	2.575GlyAsn: 2.575 ± 0.075	3.375GlyPro: 3.375 ± 0.063	2.913GlyGln: 2.913 ± 0.065	4.961GlyArg: 4.961 ± 0.079	5.882GlySer: 5.882 ± 0.09	5.012GlyThr: 5.012 ± 0.097	6.607GlyVal: 6.607 ± 0.074	1.306GlyTrp: 1.306 ± 0.04	2.129GlyTyr: 2.129 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.36HisAla: 2.36 ± 0.055	0.233HisCys: 0.233 ± 0.015	1.265HisAsp: 1.265 ± 0.04	1.551HisGlu: 1.551 ± 0.04	0.714HisPhe: 0.714 ± 0.032	1.58HisGly: 1.58 ± 0.044	0.559HisHis: 0.559 ± 0.027	1.042HisIle: 1.042 ± 0.034	0.672HisLys: 0.672 ± 0.026	1.848HisLeu: 1.848 ± 0.052	0.427HisMet: 0.427 ± 0.023	0.612HisAsn: 0.612 ± 0.027	1.231HisPro: 1.231 ± 0.036	0.605HisGln: 0.605 ± 0.022	1.297HisArg: 1.297 ± 0.042	1.121HisSer: 1.121 ± 0.028	1.16HisThr: 1.16 ± 0.04	1.38HisVal: 1.38 ± 0.034	0.286HisTrp: 0.286 ± 0.017	0.499HisTyr: 0.499 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.574IleAla: 6.574 ± 0.087	0.573IleCys: 0.573 ± 0.027	4.611IleAsp: 4.611 ± 0.072	4.849IleGlu: 4.849 ± 0.08	1.496IlePhe: 1.496 ± 0.044	4.951IleGly: 4.951 ± 0.088	1.005IleHis: 1.005 ± 0.034	2.489IleIle: 2.489 ± 0.062	1.693IleLys: 1.693 ± 0.051	3.874IleLeu: 3.874 ± 0.083	0.942IleMet: 0.942 ± 0.032	1.87IleAsn: 1.87 ± 0.052	2.489IlePro: 2.489 ± 0.051	1.505IleGln: 1.505 ± 0.046	3.627IleArg: 3.627 ± 0.071	3.379IleSer: 3.379 ± 0.068	3.176IleThr: 3.176 ± 0.06	4.241IleVal: 4.241 ± 0.073	0.612IleTrp: 0.612 ± 0.026	1.106IleTyr: 1.106 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.409LysAla: 3.409 ± 0.076	0.237LysCys: 0.237 ± 0.016	1.662LysAsp: 1.662 ± 0.05	1.761LysGlu: 1.761 ± 0.049	0.905LysPhe: 0.905 ± 0.035	2.297LysGly: 2.297 ± 0.05	0.815LysHis: 0.815 ± 0.032	1.624LysIle: 1.624 ± 0.05	1.576LysLys: 1.576 ± 0.061	3.618LysLeu: 3.618 ± 0.073	0.672LysMet: 0.672 ± 0.024	0.887LysAsn: 0.887 ± 0.032	2.247LysPro: 2.247 ± 0.052	1.331LysGln: 1.331 ± 0.039	2.539LysArg: 2.539 ± 0.055	2.05LysSer: 2.05 ± 0.048	1.781LysThr: 1.781 ± 0.047	2.108LysVal: 2.108 ± 0.059	0.408LysTrp: 0.408 ± 0.022	0.704LysTyr: 0.704 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	11.048LeuAla: 11.048 ± 0.14	0.973LeuCys: 0.973 ± 0.032	6.376LeuAsp: 6.376 ± 0.092	5.843LeuGlu: 5.843 ± 0.081	3.023LeuPhe: 3.023 ± 0.061	8.139LeuGly: 8.139 ± 0.096	1.739LeuHis: 1.739 ± 0.043	5.351LeuIle: 5.351 ± 0.089	2.725LeuLys: 2.725 ± 0.065	8.63LeuLeu: 8.63 ± 0.13	2.01LeuMet: 2.01 ± 0.051	2.656LeuAsn: 2.656 ± 0.055	4.593LeuPro: 4.593 ± 0.077	2.375LeuGln: 2.375 ± 0.049	6.191LeuArg: 6.191 ± 0.094	6.145LeuSer: 6.145 ± 0.089	5.483LeuThr: 5.483 ± 0.075	7.266LeuVal: 7.266 ± 0.099	1.023LeuTrp: 1.023 ± 0.032	1.823LeuTyr: 1.823 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	2.168MetAla: 2.168 ± 0.052	0.231MetCys: 0.231 ± 0.016	1.233MetAsp: 1.233 ± 0.034	0.997MetGlu: 0.997 ± 0.034	0.766MetPhe: 0.766 ± 0.031	1.819MetGly: 1.819 ± 0.042	0.537MetHis: 0.537 ± 0.02	1.339MetIle: 1.339 ± 0.04	0.832MetLys: 0.832 ± 0.033	2.602MetLeu: 2.602 ± 0.06	0.603MetMet: 0.603 ± 0.028	0.785MetAsn: 0.785 ± 0.026	1.49MetPro: 1.49 ± 0.037	0.821MetGln: 0.821 ± 0.028	1.67MetArg: 1.67 ± 0.041	1.739MetSer: 1.739 ± 0.046	1.724MetThr: 1.724 ± 0.042	1.524MetVal: 1.524 ± 0.042	0.239MetTrp: 0.239 ± 0.017	0.448MetTyr: 0.448 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.313AsnAla: 3.313 ± 0.071	0.258AsnCys: 0.258 ± 0.016	1.992AsnAsp: 1.992 ± 0.052	2.033AsnGlu: 2.033 ± 0.048	0.994AsnPhe: 0.994 ± 0.038	2.606AsnGly: 2.606 ± 0.08	0.594AsnHis: 0.594 ± 0.027	1.539AsnIle: 1.539 ± 0.043	0.915AsnLys: 0.915 ± 0.029	2.637AsnLeu: 2.637 ± 0.061	0.601AsnMet: 0.601 ± 0.028	1.371AsnAsn: 1.371 ± 0.053	2.106AsnPro: 2.106 ± 0.052	1.1AsnGln: 1.1 ± 0.033	1.909AsnArg: 1.909 ± 0.044	1.843AsnSer: 1.843 ± 0.049	1.884AsnThr: 1.884 ± 0.051	2.0AsnVal: 2.0 ± 0.046	0.422AsnTrp: 0.422 ± 0.022	0.688AsnTyr: 0.688 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	5.102ProAla: 5.102 ± 0.076	0.334ProCys: 0.334 ± 0.02	3.719ProAsp: 3.719 ± 0.054	4.195ProGlu: 4.195 ± 0.067	1.592ProPhe: 1.592 ± 0.039	4.704ProGly: 4.704 ± 0.071	0.885ProHis: 0.885 ± 0.029	2.794ProIle: 2.794 ± 0.06	1.655ProLys: 1.655 ± 0.047	3.836ProLeu: 3.836 ± 0.062	1.269ProMet: 1.269 ± 0.035	1.605ProAsn: 1.605 ± 0.043	2.021ProPro: 2.021 ± 0.052	1.244ProGln: 1.244 ± 0.038	2.627ProArg: 2.627 ± 0.056	3.373ProSer: 3.373 ± 0.062	3.126ProThr: 3.126 ± 0.059	3.842ProVal: 3.842 ± 0.063	0.625ProTrp: 0.625 ± 0.027	0.927ProTyr: 0.927 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.433GlnAla: 3.433 ± 0.057	0.246GlnCys: 0.246 ± 0.017	1.713GlnAsp: 1.713 ± 0.045	1.773GlnGlu: 1.773 ± 0.045	1.125GlnPhe: 1.125 ± 0.03	2.362GlnGly: 2.362 ± 0.053	0.67GlnHis: 0.67 ± 0.028	2.133GlnIle: 2.133 ± 0.053	1.012GlnLys: 1.012 ± 0.032	3.302GlnLeu: 3.302 ± 0.066	0.854GlnMet: 0.854 ± 0.03	1.199GlnAsn: 1.199 ± 0.037	1.737GlnPro: 1.737 ± 0.041	1.432GlnGln: 1.432 ± 0.052	2.383GlnArg: 2.383 ± 0.055	2.217GlnSer: 2.217 ± 0.052	2.051GlnThr: 2.051 ± 0.048	2.033GlnVal: 2.033 ± 0.042	0.454GlnTrp: 0.454 ± 0.02	0.658GlnTyr: 0.658 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	6.308ArgAla: 6.308 ± 0.083	0.675ArgCys: 0.675 ± 0.029	3.958ArgAsp: 3.958 ± 0.066	4.324ArgGlu: 4.324 ± 0.078	2.619ArgPhe: 2.619 ± 0.055	4.35ArgGly: 4.35 ± 0.075	1.361ArgHis: 1.361 ± 0.043	3.608ArgIle: 3.608 ± 0.062	2.187ArgLys: 2.187 ± 0.049	6.94ArgLeu: 6.94 ± 0.093	1.6ArgMet: 1.6 ± 0.038	1.783ArgAsn: 1.783 ± 0.038	2.893ArgPro: 2.893 ± 0.062	2.204ArgGln: 2.204 ± 0.045	4.881ArgArg: 4.881 ± 0.096	4.113ArgSer: 4.113 ± 0.074	3.519ArgThr: 3.519 ± 0.076	5.374ArgVal: 5.374 ± 0.077	0.978ArgTrp: 0.978 ± 0.031	1.728ArgTyr: 1.728 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	6.437SerAla: 6.437 ± 0.093	0.648SerCys: 0.648 ± 0.029	4.232SerAsp: 4.232 ± 0.08	3.975SerGlu: 3.975 ± 0.07	2.355SerPhe: 2.355 ± 0.05	6.422SerGly: 6.422 ± 0.093	1.182SerHis: 1.182 ± 0.033	3.629SerIle: 3.629 ± 0.066	2.144SerLys: 2.144 ± 0.053	6.078SerLeu: 6.078 ± 0.099	1.65SerMet: 1.65 ± 0.04	1.956SerAsn: 1.956 ± 0.061	3.192SerPro: 3.192 ± 0.05	2.025SerGln: 2.025 ± 0.051	4.064SerArg: 4.064 ± 0.07	4.375SerSer: 4.375 ± 0.085	3.52SerThr: 3.52 ± 0.066	4.992SerVal: 4.992 ± 0.081	0.902SerTrp: 0.902 ± 0.032	1.443SerTyr: 1.443 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	5.246ThrAla: 5.246 ± 0.074	0.544ThrCys: 0.544 ± 0.023	3.888ThrAsp: 3.888 ± 0.089	3.3ThrGlu: 3.3 ± 0.066	1.942ThrPhe: 1.942 ± 0.048	5.641ThrGly: 5.641 ± 0.092	1.213ThrHis: 1.213 ± 0.038	3.499ThrIle: 3.499 ± 0.067	1.81ThrLys: 1.81 ± 0.045	5.724ThrLeu: 5.724 ± 0.085	1.106ThrMet: 1.106 ± 0.036	1.887ThrAsn: 1.887 ± 0.051	3.564ThrPro: 3.564 ± 0.071	1.77ThrGln: 1.77 ± 0.04	3.296ThrArg: 3.296 ± 0.067	3.527ThrSer: 3.527 ± 0.069	3.318ThrThr: 3.318 ± 0.074	4.151ThrVal: 4.151 ± 0.088	0.703ThrTrp: 0.703 ± 0.027	1.362ThrTyr: 1.362 ± 0.052	0.0ThrXaa: 0.0 ± 0.0
Val	6.936ValAla: 6.936 ± 0.103	0.941ValCys: 0.941 ± 0.031	4.509ValAsp: 4.509 ± 0.07	4.72ValGlu: 4.72 ± 0.083	2.887ValPhe: 2.887 ± 0.056	5.941ValGly: 5.941 ± 0.095	1.482ValHis: 1.482 ± 0.043	4.28ValIle: 4.28 ± 0.074	2.004ValLys: 2.004 ± 0.052	7.417ValLeu: 7.417 ± 0.102	1.805ValMet: 1.805 ± 0.048	2.268ValAsn: 2.268 ± 0.056	3.399ValPro: 3.399 ± 0.055	2.002ValGln: 2.002 ± 0.039	4.999ValArg: 4.999 ± 0.078	4.866ValSer: 4.866 ± 0.07	4.568ValThr: 4.568 ± 0.084	6.22ValVal: 6.22 ± 0.094	0.938ValTrp: 0.938 ± 0.033	1.773ValTyr: 1.773 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.181TrpAla: 1.181 ± 0.036	0.16TrpCys: 0.16 ± 0.012	0.74TrpAsp: 0.74 ± 0.026	0.582TrpGlu: 0.582 ± 0.025	0.531TrpPhe: 0.531 ± 0.026	0.826TrpGly: 0.826 ± 0.034	0.362TrpHis: 0.362 ± 0.021	0.938TrpIle: 0.938 ± 0.033	0.424TrpLys: 0.424 ± 0.021	1.47TrpLeu: 1.47 ± 0.043	0.381TrpMet: 0.381 ± 0.022	0.446TrpAsn: 0.446 ± 0.023	0.652TrpPro: 0.652 ± 0.029	0.509TrpGln: 0.509 ± 0.02	0.856TrpArg: 0.856 ± 0.029	0.906TrpSer: 0.906 ± 0.028	0.758TrpThr: 0.758 ± 0.034	0.941TrpVal: 0.941 ± 0.036	0.235TrpTrp: 0.235 ± 0.016	0.359TrpTyr: 0.359 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.182TyrAla: 2.182 ± 0.052	0.241TyrCys: 0.241 ± 0.015	1.775TyrAsp: 1.775 ± 0.068	1.724TyrGlu: 1.724 ± 0.055	0.859TyrPhe: 0.859 ± 0.03	1.598TyrGly: 1.598 ± 0.044	0.515TyrHis: 0.515 ± 0.021	1.061TyrIle: 1.061 ± 0.035	0.739TyrLys: 0.739 ± 0.027	1.974TyrLeu: 1.974 ± 0.045	0.449TyrMet: 0.449 ± 0.02	0.815TyrAsn: 0.815 ± 0.028	1.041TyrPro: 1.041 ± 0.037	0.779TyrGln: 0.779 ± 0.03	1.581TyrArg: 1.581 ± 0.042	1.325TyrSer: 1.325 ± 0.039	1.405TyrThr: 1.405 ± 0.045	1.468TyrVal: 1.468 ± 0.037	0.324TyrTrp: 0.324 ± 0.019	0.554TyrTyr: 0.554 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2755 proteins (989657 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---