Amino acid dipepetide frequency for Caballeronia grimmiae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.087AlaAla: 17.087 ± 0.138	1.324AlaCys: 1.324 ± 0.032	6.864AlaAsp: 6.864 ± 0.072	5.986AlaGlu: 5.986 ± 0.09	4.576AlaPhe: 4.576 ± 0.049	9.932AlaGly: 9.932 ± 0.081	2.879AlaHis: 2.879 ± 0.039	6.019AlaIle: 6.019 ± 0.062	4.182AlaLys: 4.182 ± 0.057	14.135AlaLeu: 14.135 ± 0.096	3.54AlaMet: 3.54 ± 0.044	3.381AlaAsn: 3.381 ± 0.045	5.731AlaPro: 5.731 ± 0.072	5.117AlaGln: 5.117 ± 0.064	9.378AlaArg: 9.378 ± 0.099	8.089AlaSer: 8.089 ± 0.079	6.293AlaThr: 6.293 ± 0.062	8.866AlaVal: 8.866 ± 0.08	1.656AlaTrp: 1.656 ± 0.028	2.732AlaTyr: 2.732 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.238CysAla: 1.238 ± 0.025	0.115CysCys: 0.115 ± 0.008	0.573CysAsp: 0.573 ± 0.017	0.51CysGlu: 0.51 ± 0.019	0.341CysPhe: 0.341 ± 0.014	0.99CysGly: 0.99 ± 0.024	0.251CysHis: 0.251 ± 0.011	0.445CysIle: 0.445 ± 0.016	0.231CysLys: 0.231 ± 0.012	0.744CysLeu: 0.744 ± 0.022	0.187CysMet: 0.187 ± 0.01	0.249CysAsn: 0.249 ± 0.011	0.443CysPro: 0.443 ± 0.019	0.199CysGln: 0.199 ± 0.011	0.565CysArg: 0.565 ± 0.017	0.501CysSer: 0.501 ± 0.016	0.476CysThr: 0.476 ± 0.016	0.787CysVal: 0.787 ± 0.02	0.116CysTrp: 0.116 ± 0.008	0.242CysTyr: 0.242 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	8.476AspAla: 8.476 ± 0.09	0.478AspCys: 0.478 ± 0.018	3.493AspAsp: 3.493 ± 0.053	3.704AspGlu: 3.704 ± 0.046	2.005AspPhe: 2.005 ± 0.035	4.656AspGly: 4.656 ± 0.056	1.148AspHis: 1.148 ± 0.029	2.798AspIle: 2.798 ± 0.034	1.733AspLys: 1.733 ± 0.033	5.043AspLeu: 5.043 ± 0.051	1.264AspMet: 1.264 ± 0.024	1.342AspAsn: 1.342 ± 0.029	2.821AspPro: 2.821 ± 0.042	1.505AspGln: 1.505 ± 0.029	3.551AspArg: 3.551 ± 0.05	2.493AspSer: 2.493 ± 0.047	2.779AspThr: 2.779 ± 0.041	4.54AspVal: 4.54 ± 0.058	0.911AspTrp: 0.911 ± 0.021	1.553AspTyr: 1.553 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	6.85GluAla: 6.85 ± 0.085	0.415GluCys: 0.415 ± 0.015	2.172GluAsp: 2.172 ± 0.036	2.538GluGlu: 2.538 ± 0.046	1.826GluPhe: 1.826 ± 0.031	3.547GluGly: 3.547 ± 0.053	1.474GluHis: 1.474 ± 0.027	2.651GluIle: 2.651 ± 0.036	1.848GluLys: 1.848 ± 0.036	5.41GluLeu: 5.41 ± 0.055	1.248GluMet: 1.248 ± 0.026	1.412GluAsn: 1.412 ± 0.028	2.528GluPro: 2.528 ± 0.04	2.265GluGln: 2.265 ± 0.036	5.023GluArg: 5.023 ± 0.059	2.83GluSer: 2.83 ± 0.037	2.96GluThr: 2.96 ± 0.042	3.519GluVal: 3.519 ± 0.052	0.751GluTrp: 0.751 ± 0.019	1.173GluTyr: 1.173 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.792PheAla: 4.792 ± 0.052	0.428PheCys: 0.428 ± 0.016	2.844PheAsp: 2.844 ± 0.042	2.089PheGlu: 2.089 ± 0.034	1.52PhePhe: 1.52 ± 0.042	3.667PheGly: 3.667 ± 0.052	0.784PheHis: 0.784 ± 0.022	1.794PheIle: 1.794 ± 0.032	1.078PheLys: 1.078 ± 0.026	3.033PheLeu: 3.033 ± 0.047	0.801PheMet: 0.801 ± 0.024	1.149PheAsn: 1.149 ± 0.027	1.595PhePro: 1.595 ± 0.028	0.992PheGln: 0.992 ± 0.023	1.99PheArg: 1.99 ± 0.034	2.28PheSer: 2.28 ± 0.032	2.009PheThr: 2.009 ± 0.035	3.128PheVal: 3.128 ± 0.038	0.497PheTrp: 0.497 ± 0.016	0.968PheTyr: 0.968 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	9.441GlyAla: 9.441 ± 0.085	0.846GlyCys: 0.846 ± 0.025	4.087GlyAsp: 4.087 ± 0.053	4.224GlyGlu: 4.224 ± 0.054	3.462GlyPhe: 3.462 ± 0.038	6.541GlyGly: 6.541 ± 0.083	1.871GlyHis: 1.871 ± 0.03	4.505GlyIle: 4.505 ± 0.059	3.289GlyLys: 3.289 ± 0.048	7.729GlyLeu: 7.729 ± 0.071	2.217GlyMet: 2.217 ± 0.038	2.28GlyAsn: 2.28 ± 0.036	2.817GlyPro: 2.817 ± 0.041	2.597GlyGln: 2.597 ± 0.038	5.211GlyArg: 5.211 ± 0.057	4.443GlySer: 4.443 ± 0.057	4.247GlyThr: 4.247 ± 0.053	6.86GlyVal: 6.86 ± 0.072	1.288GlyTrp: 1.288 ± 0.031	2.349GlyTyr: 2.349 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	3.158HisAla: 3.158 ± 0.039	0.266HisCys: 0.266 ± 0.013	1.406HisAsp: 1.406 ± 0.029	1.266HisGlu: 1.266 ± 0.026	0.923HisPhe: 0.923 ± 0.024	2.201HisGly: 2.201 ± 0.038	0.63HisHis: 0.63 ± 0.02	0.962HisIle: 0.962 ± 0.02	0.528HisLys: 0.528 ± 0.018	2.113HisLeu: 2.113 ± 0.035	0.537HisMet: 0.537 ± 0.017	0.505HisAsn: 0.505 ± 0.018	1.381HisPro: 1.381 ± 0.029	0.622HisGln: 0.622 ± 0.019	1.603HisArg: 1.603 ± 0.03	1.051HisSer: 1.051 ± 0.023	1.061HisThr: 1.061 ± 0.025	1.805HisVal: 1.805 ± 0.035	0.376HisTrp: 0.376 ± 0.014	0.656HisTyr: 0.656 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	7.585IleAla: 7.585 ± 0.081	0.45IleCys: 0.45 ± 0.016	3.874IleAsp: 3.874 ± 0.05	3.488IleGlu: 3.488 ± 0.039	1.484IlePhe: 1.484 ± 0.032	5.018IleGly: 5.018 ± 0.06	0.927IleHis: 0.927 ± 0.024	1.799IleIle: 1.799 ± 0.037	1.384IleLys: 1.384 ± 0.028	3.324IleLeu: 3.324 ± 0.052	0.779IleMet: 0.779 ± 0.025	1.416IleAsn: 1.416 ± 0.031	2.033IlePro: 2.033 ± 0.035	1.176IleGln: 1.176 ± 0.028	2.828IleArg: 2.828 ± 0.039	2.498IleSer: 2.498 ± 0.037	2.451IleThr: 2.451 ± 0.036	4.689IleVal: 4.689 ± 0.062	0.488IleTrp: 0.488 ± 0.016	1.031IleTyr: 1.031 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.743LysAla: 3.743 ± 0.058	0.176LysCys: 0.176 ± 0.01	1.59LysAsp: 1.59 ± 0.032	1.567LysGlu: 1.567 ± 0.032	0.906LysPhe: 0.906 ± 0.023	2.244LysGly: 2.244 ± 0.038	0.782LysHis: 0.782 ± 0.023	1.6LysIle: 1.6 ± 0.032	1.389LysLys: 1.389 ± 0.036	3.504LysLeu: 3.504 ± 0.053	0.829LysMet: 0.829 ± 0.022	0.946LysAsn: 0.946 ± 0.025	2.117LysPro: 2.117 ± 0.039	1.359LysGln: 1.359 ± 0.032	2.701LysArg: 2.701 ± 0.037	1.89LysSer: 1.89 ± 0.037	1.943LysThr: 1.943 ± 0.038	2.309LysVal: 2.309 ± 0.037	0.399LysTrp: 0.399 ± 0.015	0.696LysTyr: 0.696 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.748LeuAla: 13.748 ± 0.101	0.973LeuCys: 0.973 ± 0.025	6.057LeuAsp: 6.057 ± 0.061	4.792LeuGlu: 4.792 ± 0.054	3.568LeuPhe: 3.568 ± 0.047	7.731LeuGly: 7.731 ± 0.073	2.221LeuHis: 2.221 ± 0.035	4.772LeuIle: 4.772 ± 0.062	3.351LeuLys: 3.351 ± 0.049	9.626LeuLeu: 9.626 ± 0.094	2.283LeuMet: 2.283 ± 0.037	2.695LeuAsn: 2.695 ± 0.042	5.477LeuPro: 5.477 ± 0.053	3.146LeuGln: 3.146 ± 0.045	6.894LeuArg: 6.894 ± 0.074	6.32LeuSer: 6.32 ± 0.068	5.499LeuThr: 5.499 ± 0.054	7.343LeuVal: 7.343 ± 0.077	1.071LeuTrp: 1.071 ± 0.027	2.141LeuTyr: 2.141 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	2.495MetAla: 2.495 ± 0.033	0.196MetCys: 0.196 ± 0.011	1.019MetAsp: 1.019 ± 0.024	0.989MetGlu: 0.989 ± 0.023	0.823MetPhe: 0.823 ± 0.023	1.546MetGly: 1.546 ± 0.034	0.567MetHis: 0.567 ± 0.018	1.201MetIle: 1.201 ± 0.03	1.125MetLys: 1.125 ± 0.024	2.788MetLeu: 2.788 ± 0.042	0.649MetMet: 0.649 ± 0.017	0.984MetAsn: 0.984 ± 0.024	1.534MetPro: 1.534 ± 0.031	1.089MetGln: 1.089 ± 0.022	1.984MetArg: 1.984 ± 0.035	1.819MetSer: 1.819 ± 0.03	1.719MetThr: 1.719 ± 0.03	1.438MetVal: 1.438 ± 0.025	0.235MetTrp: 0.235 ± 0.01	0.4MetTyr: 0.4 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.8AsnAla: 3.8 ± 0.051	0.261AsnCys: 0.261 ± 0.012	1.529AsnAsp: 1.529 ± 0.029	1.447AsnGlu: 1.447 ± 0.028	1.006AsnPhe: 1.006 ± 0.024	2.576AsnGly: 2.576 ± 0.042	0.528AsnHis: 0.528 ± 0.017	1.311AsnIle: 1.311 ± 0.031	0.751AsnLys: 0.751 ± 0.022	2.589AsnLeu: 2.589 ± 0.04	0.608AsnMet: 0.608 ± 0.019	0.774AsnAsn: 0.774 ± 0.022	1.764AsnPro: 1.764 ± 0.028	0.87AsnGln: 0.87 ± 0.024	1.859AsnArg: 1.859 ± 0.033	1.323AsnSer: 1.323 ± 0.03	1.417AsnThr: 1.417 ± 0.032	2.423AsnVal: 2.423 ± 0.041	0.428AsnTrp: 0.428 ± 0.015	0.689AsnTyr: 0.689 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.155ProAla: 6.155 ± 0.066	0.347ProCys: 0.347 ± 0.013	3.197ProAsp: 3.197 ± 0.044	2.919ProGlu: 2.919 ± 0.042	1.98ProPhe: 1.98 ± 0.031	4.027ProGly: 4.027 ± 0.045	1.262ProHis: 1.262 ± 0.025	2.008ProIle: 2.008 ± 0.03	1.583ProLys: 1.583 ± 0.026	4.95ProLeu: 4.95 ± 0.058	1.119ProMet: 1.119 ± 0.024	1.474ProAsn: 1.474 ± 0.029	2.389ProPro: 2.389 ± 0.046	1.799ProGln: 1.799 ± 0.035	2.906ProArg: 2.906 ± 0.05	2.933ProSer: 2.933 ± 0.042	2.418ProThr: 2.418 ± 0.037	4.121ProVal: 4.121 ± 0.057	0.635ProTrp: 0.635 ± 0.021	1.249ProTyr: 1.249 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.304GlnAla: 4.304 ± 0.055	0.278GlnCys: 0.278 ± 0.012	1.352GlnAsp: 1.352 ± 0.027	1.421GlnGlu: 1.421 ± 0.03	1.239GlnPhe: 1.239 ± 0.023	2.446GlnGly: 2.446 ± 0.038	0.846GlnHis: 0.846 ± 0.02	1.838GlnIle: 1.838 ± 0.034	1.161GlnLys: 1.161 ± 0.025	3.459GlnLeu: 3.459 ± 0.046	1.019GlnMet: 1.019 ± 0.02	0.9GlnAsn: 0.9 ± 0.025	1.861GlnPro: 1.861 ± 0.031	1.68GlnGln: 1.68 ± 0.04	2.796GlnArg: 2.796 ± 0.043	2.085GlnSer: 2.085 ± 0.04	1.97GlnThr: 1.97 ± 0.034	2.321GlnVal: 2.321 ± 0.033	0.551GlnTrp: 0.551 ± 0.019	0.875GlnTyr: 0.875 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	8.615ArgAla: 8.615 ± 0.081	0.577ArgCys: 0.577 ± 0.018	4.033ArgAsp: 4.033 ± 0.053	4.416ArgGlu: 4.416 ± 0.051	3.088ArgPhe: 3.088 ± 0.042	4.723ArgGly: 4.723 ± 0.055	1.84ArgHis: 1.84 ± 0.033	3.873ArgIle: 3.873 ± 0.05	2.147ArgLys: 2.147 ± 0.036	7.153ArgLeu: 7.153 ± 0.075	1.952ArgMet: 1.952 ± 0.033	1.931ArgAsn: 1.931 ± 0.029	2.946ArgPro: 2.946 ± 0.038	2.371ArgGln: 2.371 ± 0.037	5.409ArgArg: 5.409 ± 0.063	3.553ArgSer: 3.553 ± 0.05	3.533ArgThr: 3.533 ± 0.047	5.435ArgVal: 5.435 ± 0.058	1.043ArgTrp: 1.043 ± 0.022	1.973ArgTyr: 1.973 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	7.007SerAla: 7.007 ± 0.067	0.464SerCys: 0.464 ± 0.015	3.032SerAsp: 3.032 ± 0.046	2.731SerGlu: 2.731 ± 0.046	2.211SerPhe: 2.211 ± 0.035	5.374SerGly: 5.374 ± 0.063	1.239SerHis: 1.239 ± 0.025	2.891SerIle: 2.891 ± 0.038	1.806SerLys: 1.806 ± 0.034	5.764SerLeu: 5.764 ± 0.057	1.57SerMet: 1.57 ± 0.027	1.711SerAsn: 1.711 ± 0.029	2.902SerPro: 2.902 ± 0.039	1.847SerGln: 1.847 ± 0.037	3.822SerArg: 3.822 ± 0.053	3.487SerSer: 3.487 ± 0.052	3.123SerThr: 3.123 ± 0.047	4.435SerVal: 4.435 ± 0.048	0.672SerTrp: 0.672 ± 0.021	1.322SerTyr: 1.322 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	5.92ThrAla: 5.92 ± 0.067	0.42ThrCys: 0.42 ± 0.017	2.717ThrAsp: 2.717 ± 0.035	2.336ThrGlu: 2.336 ± 0.042	2.001ThrPhe: 2.001 ± 0.034	4.653ThrGly: 4.653 ± 0.047	1.326ThrHis: 1.326 ± 0.029	2.614ThrIle: 2.614 ± 0.041	1.409ThrLys: 1.409 ± 0.032	6.313ThrLeu: 6.313 ± 0.062	1.241ThrMet: 1.241 ± 0.026	1.438ThrAsn: 1.438 ± 0.026	3.427ThrPro: 3.427 ± 0.043	1.877ThrGln: 1.877 ± 0.031	3.638ThrArg: 3.638 ± 0.037	2.965ThrSer: 2.965 ± 0.04	2.809ThrThr: 2.809 ± 0.046	4.319ThrVal: 4.319 ± 0.053	0.647ThrTrp: 0.647 ± 0.017	1.207ThrTyr: 1.207 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	9.41ValAla: 9.41 ± 0.074	0.803ValCys: 0.803 ± 0.021	4.453ValAsp: 4.453 ± 0.067	4.256ValGlu: 4.256 ± 0.058	2.908ValPhe: 2.908 ± 0.044	5.429ValGly: 5.429 ± 0.065	1.576ValHis: 1.576 ± 0.029	3.999ValIle: 3.999 ± 0.055	2.588ValLys: 2.588 ± 0.043	7.785ValLeu: 7.785 ± 0.073	1.93ValMet: 1.93 ± 0.037	2.274ValAsn: 2.274 ± 0.036	3.861ValPro: 3.861 ± 0.049	2.445ValGln: 2.445 ± 0.034	5.302ValArg: 5.302 ± 0.051	4.754ValSer: 4.754 ± 0.053	4.554ValThr: 4.554 ± 0.055	6.329ValVal: 6.329 ± 0.056	0.955ValTrp: 0.955 ± 0.028	1.756ValTyr: 1.756 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.118TrpAla: 1.118 ± 0.026	0.129TrpCys: 0.129 ± 0.009	0.615TrpAsp: 0.615 ± 0.019	0.486TrpGlu: 0.486 ± 0.015	0.544TrpPhe: 0.544 ± 0.018	0.844TrpGly: 0.844 ± 0.022	0.398TrpHis: 0.398 ± 0.015	0.732TrpIle: 0.732 ± 0.017	0.449TrpLys: 0.449 ± 0.018	1.808TrpLeu: 1.808 ± 0.036	0.371TrpMet: 0.371 ± 0.014	0.465TrpAsn: 0.465 ± 0.019	0.626TrpPro: 0.626 ± 0.019	0.61TrpGln: 0.61 ± 0.019	1.219TrpArg: 1.219 ± 0.029	0.794TrpSer: 0.794 ± 0.022	0.766TrpThr: 0.766 ± 0.021	0.83TrpVal: 0.83 ± 0.022	0.201TrpTrp: 0.201 ± 0.011	0.311TrpTyr: 0.311 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.825TyrAla: 2.825 ± 0.04	0.259TyrCys: 0.259 ± 0.012	1.386TyrAsp: 1.386 ± 0.029	1.274TyrGlu: 1.274 ± 0.029	1.024TyrPhe: 1.024 ± 0.024	2.16TyrGly: 2.16 ± 0.034	0.503TyrHis: 0.503 ± 0.016	0.91TyrIle: 0.91 ± 0.024	0.658TyrLys: 0.658 ± 0.022	2.44TyrLeu: 2.44 ± 0.042	0.454TyrMet: 0.454 ± 0.016	0.627TyrAsn: 0.627 ± 0.019	1.218TyrPro: 1.218 ± 0.025	0.835TyrGln: 0.835 ± 0.019	1.931TyrArg: 1.931 ± 0.035	1.302TyrSer: 1.302 ± 0.028	1.249TyrThr: 1.249 ± 0.028	1.871TyrVal: 1.871 ± 0.032	0.396TyrTrp: 0.396 ± 0.015	0.657TyrTyr: 0.657 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5937 proteins (1846429 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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