Amino acid dipepetide frequency for Beihai razor shell virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.162AlaAla: 7.162 ± 2.376
1.508AlaCys: 1.508 ± 0.432
3.015AlaAsp: 3.015 ± 0.43
1.885AlaGlu: 1.885 ± 0.43
4.523AlaPhe: 4.523 ± 0.644
3.392AlaGly: 3.392 ± 0.649
1.508AlaHis: 1.508 ± 0.215
1.508AlaIle: 1.508 ± 0.432
2.639AlaLys: 2.639 ± 0.861
6.408AlaLeu: 6.408 ± 0.866
2.262AlaMet: 2.262 ± 1.187
2.639AlaAsn: 2.639 ± 0.433
4.523AlaPro: 4.523 ± 0.002
1.508AlaGln: 1.508 ± 0.215
1.885AlaArg: 1.885 ± 0.217
5.277AlaSer: 5.277 ± 2.159
4.9AlaThr: 4.9 ± 1.728
6.031AlaVal: 6.031 ± 1.081
1.131AlaTrp: 1.131 ± 0.647
4.9AlaTyr: 4.9 ± 0.434
0.0AlaXaa: 0.0 ± 0.0
Cys
1.885CysAla: 1.885 ± 1.077
0.377CysCys: 0.377 ± 0.215
1.885CysAsp: 1.885 ± 1.077
1.131CysGlu: 1.131 ± 0.646
0.0CysPhe: 0.0 ± 0.0
1.885CysGly: 1.885 ± 1.077
0.754CysHis: 0.754 ± 0.216
0.754CysIle: 0.754 ± 0.216
1.131CysLys: 1.131 ± 0.646
1.508CysLeu: 1.508 ± 0.215
0.0CysMet: 0.0 ± 0.0
1.508CysAsn: 1.508 ± 0.432
1.131CysPro: 1.131 ± 0.646
0.754CysGln: 0.754 ± 0.431
1.508CysArg: 1.508 ± 0.432
0.754CysSer: 0.754 ± 0.431
1.131CysThr: 1.131 ± 0.646
1.131CysVal: 1.131 ± 0.646
0.0CysTrp: 0.0 ± 0.0
1.508CysTyr: 1.508 ± 0.432
0.0CysXaa: 0.0 ± 0.0
Asp
4.523AspAla: 4.523 ± 0.644
1.508AspCys: 1.508 ± 0.862
4.9AspAsp: 4.9 ± 2.154
4.523AspGlu: 4.523 ± 0.002
4.523AspPhe: 4.523 ± 0.644
4.523AspGly: 4.523 ± 0.649
1.131AspHis: 1.131 ± 0.001
5.277AspIle: 5.277 ± 1.722
3.769AspLys: 3.769 ± 1.507
1.885AspLeu: 1.885 ± 0.217
0.377AspMet: 0.377 ± 0.215
2.639AspAsn: 2.639 ± 1.08
3.769AspPro: 3.769 ± 2.374
0.754AspGln: 0.754 ± 0.216
2.262AspArg: 2.262 ± 1.293
4.9AspSer: 4.9 ± 0.213
3.769AspThr: 3.769 ± 0.433
3.392AspVal: 3.392 ± 0.002
0.377AspTrp: 0.377 ± 0.431
3.015AspTyr: 3.015 ± 1.723
0.0AspXaa: 0.0 ± 0.0
Glu
1.508GluAla: 1.508 ± 0.215
0.377GluCys: 0.377 ± 0.215
2.262GluAsp: 2.262 ± 0.646
1.508GluGlu: 1.508 ± 0.862
3.392GluPhe: 3.392 ± 0.649
3.015GluGly: 3.015 ± 0.217
1.131GluHis: 1.131 ± 0.646
3.015GluIle: 3.015 ± 0.217
1.885GluLys: 1.885 ± 1.077
6.785GluLeu: 6.785 ± 1.297
0.377GluMet: 0.377 ± 0.215
1.508GluAsn: 1.508 ± 0.432
2.639GluPro: 2.639 ± 0.433
3.015GluGln: 3.015 ± 0.43
3.015GluArg: 3.015 ± 1.723
2.639GluSer: 2.639 ± 0.861
2.639GluThr: 2.639 ± 0.433
3.392GluVal: 3.392 ± 0.002
0.754GluTrp: 0.754 ± 0.431
1.131GluTyr: 1.131 ± 0.647
0.0GluXaa: 0.0 ± 0.0
Phe
2.639PheAla: 2.639 ± 0.861
2.262PheCys: 2.262 ± 1.293
2.639PheAsp: 2.639 ± 0.214
3.392PheGlu: 3.392 ± 0.649
2.639PhePhe: 2.639 ± 0.214
3.392PheGly: 3.392 ± 0.002
1.131PheHis: 1.131 ± 0.647
2.639PheIle: 2.639 ± 0.214
2.262PheLys: 2.262 ± 0.001
3.015PheLeu: 3.015 ± 1.076
1.131PheMet: 1.131 ± 0.646
4.523PheAsn: 4.523 ± 0.002
3.015PhePro: 3.015 ± 0.217
1.131PheGln: 1.131 ± 0.001
1.885PheArg: 1.885 ± 1.077
4.146PheSer: 4.146 ± 0.429
3.769PheThr: 3.769 ± 1.727
4.9PheVal: 4.9 ± 0.434
0.0PheTrp: 0.0 ± 0.0
0.754PheTyr: 0.754 ± 0.431
0.0PheXaa: 0.0 ± 0.0
Gly
1.885GlyAla: 1.885 ± 0.864
0.377GlyCys: 0.377 ± 0.215
3.015GlyAsp: 3.015 ± 1.076
4.146GlyGlu: 4.146 ± 0.429
1.885GlyPhe: 1.885 ± 0.217
2.639GlyGly: 2.639 ± 0.433
0.754GlyHis: 0.754 ± 0.216
3.015GlyIle: 3.015 ± 0.43
1.885GlyLys: 1.885 ± 1.077
3.392GlyLeu: 3.392 ± 1.292
1.508GlyMet: 1.508 ± 0.432
4.146GlyAsn: 4.146 ± 1.076
2.639GlyPro: 2.639 ± 1.726
0.754GlyGln: 0.754 ± 0.216
2.639GlyArg: 2.639 ± 0.433
5.654GlySer: 5.654 ± 0.65
3.769GlyThr: 3.769 ± 0.433
6.031GlyVal: 6.031 ± 1.728
1.508GlyTrp: 1.508 ± 0.215
3.769GlyTyr: 3.769 ± 0.433
0.0GlyXaa: 0.0 ± 0.0
His
4.146HisAla: 4.146 ± 0.218
0.0HisCys: 0.0 ± 0.0
1.885HisAsp: 1.885 ± 0.217
0.754HisGlu: 0.754 ± 0.431
0.754HisPhe: 0.754 ± 0.431
0.754HisGly: 0.754 ± 0.431
1.885HisHis: 1.885 ± 0.43
1.131HisIle: 1.131 ± 0.647
1.131HisLys: 1.131 ± 0.001
1.508HisLeu: 1.508 ± 0.215
0.0HisMet: 0.0 ± 0.0
1.131HisAsn: 1.131 ± 0.647
1.508HisPro: 1.508 ± 0.862
0.377HisGln: 0.377 ± 0.215
3.769HisArg: 3.769 ± 0.433
1.508HisSer: 1.508 ± 0.215
1.131HisThr: 1.131 ± 0.001
1.508HisVal: 1.508 ± 0.862
0.0HisTrp: 0.0 ± 0.0
0.754HisTyr: 0.754 ± 0.216
0.0HisXaa: 0.0 ± 0.0
Ile
4.9IleAla: 4.9 ± 1.728
1.131IleCys: 1.131 ± 0.001
2.639IleAsp: 2.639 ± 0.433
2.639IleGlu: 2.639 ± 0.214
3.015IlePhe: 3.015 ± 0.43
2.639IleGly: 2.639 ± 0.214
1.885IleHis: 1.885 ± 0.43
2.262IleIle: 2.262 ± 0.646
3.769IleLys: 3.769 ± 0.86
1.885IleLeu: 1.885 ± 0.217
1.131IleMet: 1.131 ± 0.646
3.769IleAsn: 3.769 ± 1.727
3.392IlePro: 3.392 ± 1.292
3.392IleGln: 3.392 ± 1.292
1.885IleArg: 1.885 ± 1.077
6.785IleSer: 6.785 ± 1.297
3.015IleThr: 3.015 ± 0.864
4.523IleVal: 4.523 ± 1.291
1.131IleTrp: 1.131 ± 0.001
1.508IleTyr: 1.508 ± 1.079
0.0IleXaa: 0.0 ± 0.0
Lys
4.146LysAla: 4.146 ± 0.429
0.754LysCys: 0.754 ± 0.431
1.508LysAsp: 1.508 ± 0.862
1.885LysGlu: 1.885 ± 1.077
3.769LysPhe: 3.769 ± 0.86
2.262LysGly: 2.262 ± 1.293
0.754LysHis: 0.754 ± 0.431
3.015LysIle: 3.015 ± 0.43
3.769LysLys: 3.769 ± 1.507
2.262LysLeu: 2.262 ± 0.646
1.508LysMet: 1.508 ± 0.215
3.769LysAsn: 3.769 ± 1.08
4.523LysPro: 4.523 ± 0.644
0.754LysGln: 0.754 ± 0.216
2.262LysArg: 2.262 ± 1.293
3.015LysSer: 3.015 ± 0.43
1.131LysThr: 1.131 ± 0.646
4.9LysVal: 4.9 ± 1.507
0.377LysTrp: 0.377 ± 0.215
2.639LysTyr: 2.639 ± 1.508
0.0LysXaa: 0.0 ± 0.0
Leu
6.785LeuAla: 6.785 ± 1.944
1.885LeuCys: 1.885 ± 0.43
6.031LeuAsp: 6.031 ± 1.506
1.885LeuGlu: 1.885 ± 0.217
3.015LeuPhe: 3.015 ± 0.864
1.131LeuGly: 1.131 ± 0.646
2.262LeuHis: 2.262 ± 0.648
5.277LeuIle: 5.277 ± 1.722
4.523LeuLys: 4.523 ± 1.291
3.392LeuLeu: 3.392 ± 0.002
1.131LeuMet: 1.131 ± 0.001
4.523LeuAsn: 4.523 ± 0.002
2.262LeuPro: 2.262 ± 0.001
1.508LeuGln: 1.508 ± 0.215
4.523LeuArg: 4.523 ± 0.644
6.031LeuSer: 6.031 ± 0.434
4.523LeuThr: 4.523 ± 0.644
5.277LeuVal: 5.277 ± 0.428
0.377LeuTrp: 0.377 ± 0.215
3.015LeuTyr: 3.015 ± 0.864
0.0LeuXaa: 0.0 ± 0.0
Met
2.262MetAla: 2.262 ± 0.648
0.754MetCys: 0.754 ± 0.431
1.885MetAsp: 1.885 ± 0.43
0.754MetGlu: 0.754 ± 0.216
2.639MetPhe: 2.639 ± 0.861
2.262MetGly: 2.262 ± 0.648
1.131MetHis: 1.131 ± 0.001
1.131MetIle: 1.131 ± 0.646
1.131MetLys: 1.131 ± 0.001
1.131MetLeu: 1.131 ± 0.001
1.508MetMet: 1.508 ± 0.862
1.508MetAsn: 1.508 ± 0.432
2.262MetPro: 2.262 ± 0.648
0.377MetGln: 0.377 ± 0.215
2.262MetArg: 2.262 ± 0.001
2.639MetSer: 2.639 ± 1.08
1.508MetThr: 1.508 ± 0.215
1.508MetVal: 1.508 ± 0.215
0.377MetTrp: 0.377 ± 0.215
0.377MetTyr: 0.377 ± 0.431
0.0MetXaa: 0.0 ± 0.0
Asn
2.639AsnAla: 2.639 ± 0.214
1.131AsnCys: 1.131 ± 0.646
3.769AsnAsp: 3.769 ± 0.433
1.885AsnGlu: 1.885 ± 1.51
1.885AsnPhe: 1.885 ± 0.43
4.523AsnGly: 4.523 ± 0.649
1.508AsnHis: 1.508 ± 0.432
3.392AsnIle: 3.392 ± 0.649
1.885AsnLys: 1.885 ± 0.217
3.015AsnLeu: 3.015 ± 0.864
1.508AsnMet: 1.508 ± 0.432
3.015AsnAsn: 3.015 ± 0.217
2.262AsnPro: 2.262 ± 0.001
1.508AsnGln: 1.508 ± 0.215
1.508AsnArg: 1.508 ± 0.215
2.639AsnSer: 2.639 ± 0.433
4.523AsnThr: 4.523 ± 3.237
4.9AsnVal: 4.9 ± 0.434
1.508AsnTrp: 1.508 ± 1.079
2.639AsnTyr: 2.639 ± 0.861
0.0AsnXaa: 0.0 ± 0.0
Pro
2.262ProAla: 2.262 ± 0.648
0.377ProCys: 0.377 ± 0.215
3.392ProAsp: 3.392 ± 0.649
2.639ProGlu: 2.639 ± 0.214
2.262ProPhe: 2.262 ± 1.942
2.639ProGly: 2.639 ± 0.214
1.885ProHis: 1.885 ± 0.43
2.639ProIle: 2.639 ± 0.214
1.885ProLys: 1.885 ± 0.43
6.031ProLeu: 6.031 ± 0.212
2.639ProMet: 2.639 ± 0.214
1.885ProAsn: 1.885 ± 0.217
0.754ProPro: 0.754 ± 0.431
3.392ProGln: 3.392 ± 1.292
1.885ProArg: 1.885 ± 0.217
3.015ProSer: 3.015 ± 1.076
3.769ProThr: 3.769 ± 2.374
4.146ProVal: 4.146 ± 0.865
0.754ProTrp: 0.754 ± 0.216
2.639ProTyr: 2.639 ± 1.726
0.0ProXaa: 0.0 ± 0.0
Gln
2.262GlnAla: 2.262 ± 0.646
0.754GlnCys: 0.754 ± 0.431
2.262GlnAsp: 2.262 ± 0.646
1.508GlnGlu: 1.508 ± 0.862
2.262GlnPhe: 2.262 ± 1.293
2.262GlnGly: 2.262 ± 0.001
0.754GlnHis: 0.754 ± 0.431
1.508GlnIle: 1.508 ± 1.079
1.508GlnLys: 1.508 ± 0.862
2.639GlnLeu: 2.639 ± 0.433
0.754GlnMet: 0.754 ± 0.431
0.377GlnAsn: 0.377 ± 0.431
0.754GlnPro: 0.754 ± 0.431
1.508GlnGln: 1.508 ± 0.862
2.262GlnArg: 2.262 ± 0.001
3.392GlnSer: 3.392 ± 0.645
1.131GlnThr: 1.131 ± 0.647
1.508GlnVal: 1.508 ± 0.432
0.0GlnTrp: 0.0 ± 0.0
0.377GlnTyr: 0.377 ± 0.431
0.0GlnXaa: 0.0 ± 0.0
Arg
2.262ArgAla: 2.262 ± 0.646
1.131ArgCys: 1.131 ± 0.001
2.262ArgAsp: 2.262 ± 1.293
1.885ArgGlu: 1.885 ± 1.077
1.131ArgPhe: 1.131 ± 0.647
1.508ArgGly: 1.508 ± 1.726
3.015ArgHis: 3.015 ± 0.43
4.146ArgIle: 4.146 ± 0.429
3.769ArgLys: 3.769 ± 1.507
5.277ArgLeu: 5.277 ± 1.722
1.885ArgMet: 1.885 ± 0.864
1.508ArgAsn: 1.508 ± 0.215
1.131ArgPro: 1.131 ± 0.001
1.885ArgGln: 1.885 ± 1.077
2.262ArgArg: 2.262 ± 1.293
6.031ArgSer: 6.031 ± 2.8
4.146ArgThr: 4.146 ± 0.865
2.262ArgVal: 2.262 ± 0.001
1.885ArgTrp: 1.885 ± 0.43
3.769ArgTyr: 3.769 ± 1.08
0.0ArgXaa: 0.0 ± 0.0
Ser
6.031SerAla: 6.031 ± 3.022
0.754SerCys: 0.754 ± 0.431
5.277SerAsp: 5.277 ± 1.075
3.015SerGlu: 3.015 ± 0.217
3.015SerPhe: 3.015 ± 1.723
6.408SerGly: 6.408 ± 1.075
1.508SerHis: 1.508 ± 0.432
5.654SerIle: 5.654 ± 0.65
4.523SerLys: 4.523 ± 1.291
3.769SerLeu: 3.769 ± 0.214
3.392SerMet: 3.392 ± 0.645
5.277SerAsn: 5.277 ± 0.865
2.262SerPro: 2.262 ± 0.001
2.262SerGln: 2.262 ± 0.646
7.539SerArg: 7.539 ± 0.867
7.162SerSer: 7.162 ± 2.376
4.146SerThr: 4.146 ± 0.218
6.408SerVal: 6.408 ± 1.075
0.0SerTrp: 0.0 ± 0.0
4.146SerTyr: 4.146 ± 0.218
0.0SerXaa: 0.0 ± 0.0
Thr
4.146ThrAla: 4.146 ± 2.805
2.262ThrCys: 2.262 ± 0.001
3.769ThrAsp: 3.769 ± 2.374
3.392ThrGlu: 3.392 ± 0.002
3.392ThrPhe: 3.392 ± 1.296
3.392ThrGly: 3.392 ± 0.649
0.377ThrHis: 0.377 ± 0.215
4.9ThrIle: 4.9 ± 1.728
0.754ThrLys: 0.754 ± 0.216
4.9ThrLeu: 4.9 ± 0.213
2.639ThrMet: 2.639 ± 0.254
2.639ThrAsn: 2.639 ± 1.08
5.654ThrPro: 5.654 ± 0.65
1.131ThrGln: 1.131 ± 1.294
3.392ThrArg: 3.392 ± 0.645
4.9ThrSer: 4.9 ± 0.213
3.769ThrThr: 3.769 ± 1.727
5.654ThrVal: 5.654 ± 1.944
0.754ThrTrp: 0.754 ± 0.431
1.885ThrTyr: 1.885 ± 0.864
0.0ThrXaa: 0.0 ± 0.0
Val
3.769ValAla: 3.769 ± 0.214
2.639ValCys: 2.639 ± 0.861
4.523ValAsp: 4.523 ± 0.002
3.769ValGlu: 3.769 ± 0.433
3.769ValPhe: 3.769 ± 1.507
4.9ValGly: 4.9 ± 1.728
1.131ValHis: 1.131 ± 0.646
3.769ValIle: 3.769 ± 1.08
4.523ValLys: 4.523 ± 1.291
4.523ValLeu: 4.523 ± 0.644
2.639ValMet: 2.639 ± 0.214
3.769ValAsn: 3.769 ± 0.214
4.523ValPro: 4.523 ± 1.943
2.639ValGln: 2.639 ± 0.433
4.146ValArg: 4.146 ± 1.723
6.785ValSer: 6.785 ± 0.643
5.277ValThr: 5.277 ± 2.806
6.408ValVal: 6.408 ± 2.16
0.377ValTrp: 0.377 ± 0.431
3.392ValTyr: 3.392 ± 0.002
0.0ValXaa: 0.0 ± 0.0
Trp
0.754TrpAla: 0.754 ± 0.216
0.0TrpCys: 0.0 ± 0.0
0.377TrpAsp: 0.377 ± 0.431
0.754TrpGlu: 0.754 ± 0.431
1.131TrpPhe: 1.131 ± 0.001
0.0TrpGly: 0.0 ± 0.0
0.377TrpHis: 0.377 ± 0.215
0.754TrpIle: 0.754 ± 0.431
0.377TrpLys: 0.377 ± 0.215
1.131TrpLeu: 1.131 ± 0.647
0.377TrpMet: 0.377 ± 0.431
0.377TrpAsn: 0.377 ± 0.431
0.377TrpPro: 0.377 ± 0.215
0.0TrpGln: 0.0 ± 0.0
1.508TrpArg: 1.508 ± 1.079
1.131TrpSer: 1.131 ± 0.646
0.754TrpThr: 0.754 ± 0.431
0.377TrpVal: 0.377 ± 0.215
0.0TrpTrp: 0.0 ± 0.0
1.131TrpTyr: 1.131 ± 0.001
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.015TyrAla: 3.015 ± 0.217
0.754TyrCys: 0.754 ± 0.216
4.523TyrAsp: 4.523 ± 1.296
2.639TyrGlu: 2.639 ± 0.433
2.262TyrPhe: 2.262 ± 0.648
1.885TyrGly: 1.885 ± 0.43
0.754TyrHis: 0.754 ± 0.216
1.508TyrIle: 1.508 ± 0.862
1.885TyrLys: 1.885 ± 0.864
4.9TyrLeu: 4.9 ± 0.86
2.262TyrMet: 2.262 ± 0.648
1.131TyrAsn: 1.131 ± 0.001
1.508TyrPro: 1.508 ± 0.432
1.131TyrGln: 1.131 ± 0.647
0.754TyrArg: 0.754 ± 0.431
4.146TyrSer: 4.146 ± 0.865
4.9TyrThr: 4.9 ± 0.434
3.015TyrVal: 3.015 ± 0.217
0.377TyrTrp: 0.377 ± 0.215
1.508TyrTyr: 1.508 ± 0.432
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2654 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski