Simian immunodeficiency virus - agm.sab-1

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Simian immunodeficiency virus; Simian immunodeficiency virus - agm; Simian immunodeficiency virus - agm.sab

Average proteome isoelectric point is 7.62

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q87114|Q87114_SIVSA Protein Nef OS=Simian immunodeficiency virus - agm.sab-1 OX=349974 PE=3 SV=1
MM1 pKa = 7.45GGKK4 pKa = 9.23SSKK7 pKa = 8.35QQQRR11 pKa = 11.84HH12 pKa = 5.13SLWLWSKK19 pKa = 10.46LRR21 pKa = 11.84QAPVIQYY28 pKa = 11.5DD29 pKa = 3.71MLADD33 pKa = 4.09PLLGQSSHH41 pKa = 5.68IQEE44 pKa = 4.33EE45 pKa = 4.84CAKK48 pKa = 10.07SLRR51 pKa = 11.84DD52 pKa = 3.42GLIRR56 pKa = 11.84QGDD59 pKa = 3.75SSRR62 pKa = 11.84TEE64 pKa = 3.76EE65 pKa = 4.27GVKK68 pKa = 9.43MKK70 pKa = 10.49HH71 pKa = 6.13QGRR74 pKa = 11.84QPSWYY79 pKa = 9.91DD80 pKa = 3.18EE81 pKa = 4.57DD82 pKa = 4.09EE83 pKa = 4.65EE84 pKa = 4.76EE85 pKa = 4.25VGFPVRR91 pKa = 11.84PCLPLRR97 pKa = 11.84AMTYY101 pKa = 10.71KK102 pKa = 10.68LAIDD106 pKa = 4.52FGHH109 pKa = 6.47FLKK112 pKa = 10.86EE113 pKa = 3.87KK114 pKa = 10.43GGLEE118 pKa = 4.14GIYY121 pKa = 10.2YY122 pKa = 9.05SEE124 pKa = 4.11RR125 pKa = 11.84RR126 pKa = 11.84KK127 pKa = 10.61KK128 pKa = 10.52ILDD131 pKa = 4.03LYY133 pKa = 11.0ALNEE137 pKa = 3.9WGIVDD142 pKa = 4.07GWQNYY147 pKa = 7.22TDD149 pKa = 4.35GPGTRR154 pKa = 11.84YY155 pKa = 8.82PKK157 pKa = 10.64CFGWCFKK164 pKa = 10.5LVPVDD169 pKa = 4.5LSEE172 pKa = 3.99EE173 pKa = 4.11AKK175 pKa = 10.87NSEE178 pKa = 4.28NHH180 pKa = 6.38CLLHH184 pKa = 6.22PAQVAYY190 pKa = 10.13EE191 pKa = 4.06DD192 pKa = 4.67DD193 pKa = 3.4AWKK196 pKa = 8.39EE197 pKa = 3.95TLVWKK202 pKa = 10.02FDD204 pKa = 3.79PLLAVDD210 pKa = 3.89YY211 pKa = 9.51VAWRR215 pKa = 11.84LHH217 pKa = 6.07PEE219 pKa = 4.08QVPSAQGG226 pKa = 2.99

Molecular weight: 26.07 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q87113|Q87113_SIVSA Envelope glycoprotein gp160 OS=Simian immunodeficiency virus - agm.sab-1 OX=349974 PE=4 SV=1
MM1 pKa = 7.71SLGQEE6 pKa = 3.73EE7 pKa = 4.75LLRR10 pKa = 11.84RR11 pKa = 11.84FRR13 pKa = 11.84IIKK16 pKa = 9.8FLYY19 pKa = 6.17TTNPYY24 pKa = 10.39PPGQGTARR32 pKa = 11.84QRR34 pKa = 11.84RR35 pKa = 11.84RR36 pKa = 11.84ARR38 pKa = 11.84QRR40 pKa = 11.84WAKK43 pKa = 9.91QRR45 pKa = 11.84QQVIHH50 pKa = 5.79LAEE53 pKa = 5.58RR54 pKa = 11.84ILEE57 pKa = 4.4TPVSQIDD64 pKa = 3.55HH65 pKa = 7.26LAQEE69 pKa = 4.78FDD71 pKa = 4.19QLVLDD76 pKa = 4.91NLQQPPSLPPGHH88 pKa = 6.37PTEE91 pKa = 4.26NQTANSSSS99 pKa = 3.14

Molecular weight: 11.5 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8

0

8

3097

73

1039

387.1

44.09

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.748 ± 0.333

2.228 ± 0.485

3.972 ± 0.326

6.716 ± 0.508

2.712 ± 0.313

7.039 ± 0.531

2.293 ± 0.393

5.651 ± 0.897

6.813 ± 0.384

8.298 ± 0.278

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.744 ± 0.155

4.488 ± 0.764

6.167 ± 0.736

6.619 ± 0.66

5.683 ± 0.448

4.811 ± 0.47

5.392 ± 0.516

6.103 ± 0.29

3.229 ± 0.38

3.294 ± 0.274
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski