Amino acid dipepetide frequency for Chapare mammarenavirus (isolate Human/Bolivia/810419/2003)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.686AlaAla: 2.686 ± 0.495
0.895AlaCys: 0.895 ± 0.331
2.387AlaAsp: 2.387 ± 1.217
2.089AlaGlu: 2.089 ± 0.617
0.895AlaPhe: 0.895 ± 0.331
2.387AlaGly: 2.387 ± 1.693
0.597AlaHis: 0.597 ± 0.324
3.283AlaIle: 3.283 ± 1.457
2.387AlaLys: 2.387 ± 0.364
8.057AlaLeu: 8.057 ± 0.675
1.492AlaMet: 1.492 ± 0.665
1.492AlaAsn: 1.492 ± 0.499
1.194AlaPro: 1.194 ± 1.313
1.492AlaGln: 1.492 ± 1.128
1.492AlaArg: 1.492 ± 0.487
0.895AlaSer: 0.895 ± 0.331
1.791AlaThr: 1.791 ± 0.115
1.492AlaVal: 1.492 ± 0.792
0.0AlaTrp: 0.0 ± 0.0
1.492AlaTyr: 1.492 ± 0.81
0.0AlaXaa: 0.0 ± 0.0
Cys
0.597CysAla: 0.597 ± 0.353
0.298CysCys: 0.298 ± 0.606
1.791CysAsp: 1.791 ± 0.572
1.194CysGlu: 1.194 ± 0.418
1.791CysPhe: 1.791 ± 0.781
0.895CysGly: 0.895 ± 0.764
0.298CysHis: 0.298 ± 0.162
0.597CysIle: 0.597 ± 0.324
2.387CysLys: 2.387 ± 0.364
2.387CysLeu: 2.387 ± 1.876
0.597CysMet: 0.597 ± 0.353
1.791CysAsn: 1.791 ± 0.781
0.597CysPro: 0.597 ± 0.427
0.895CysGln: 0.895 ± 0.486
1.194CysArg: 1.194 ± 0.668
1.791CysSer: 1.791 ± 0.572
0.298CysThr: 0.298 ± 0.515
2.686CysVal: 2.686 ± 0.907
0.895CysTrp: 0.895 ± 0.764
1.492CysTyr: 1.492 ± 0.487
0.0CysXaa: 0.0 ± 0.0
Asp
1.194AspAla: 1.194 ± 0.322
0.597AspCys: 0.597 ± 0.877
2.387AspAsp: 2.387 ± 0.906
4.178AspGlu: 4.178 ± 1.345
5.372AspPhe: 5.372 ± 1.041
2.686AspGly: 2.686 ± 1.362
1.492AspHis: 1.492 ± 0.802
3.581AspIle: 3.581 ± 0.555
2.387AspLys: 2.387 ± 0.318
8.356AspLeu: 8.356 ± 2.957
2.984AspMet: 2.984 ± 0.917
2.387AspAsn: 2.387 ± 0.643
2.387AspPro: 2.387 ± 0.833
3.283AspGln: 3.283 ± 1.37
1.791AspArg: 1.791 ± 0.572
3.283AspSer: 3.283 ± 1.107
3.283AspThr: 3.283 ± 0.489
2.984AspVal: 2.984 ± 1.023
1.194AspTrp: 1.194 ± 0.418
1.194AspTyr: 1.194 ± 0.648
0.0AspXaa: 0.0 ± 0.0
Glu
1.791GluAla: 1.791 ± 0.115
2.089GluCys: 2.089 ± 1.134
2.984GluAsp: 2.984 ± 1.187
4.775GluGlu: 4.775 ± 1.747
2.984GluPhe: 2.984 ± 1.177
0.895GluGly: 0.895 ± 0.779
2.387GluHis: 2.387 ± 0.364
5.372GluIle: 5.372 ± 1.041
2.984GluLys: 2.984 ± 1.167
8.356GluLeu: 8.356 ± 0.89
2.387GluMet: 2.387 ± 1.016
3.879GluAsn: 3.879 ± 0.67
2.686GluPro: 2.686 ± 1.034
2.686GluGln: 2.686 ± 1.059
3.283GluArg: 3.283 ± 0.485
5.073GluSer: 5.073 ± 1.136
3.581GluThr: 3.581 ± 0.684
3.581GluVal: 3.581 ± 1.232
0.895GluTrp: 0.895 ± 0.39
0.895GluTyr: 0.895 ± 0.39
0.0GluXaa: 0.0 ± 0.0
Phe
0.895PheAla: 0.895 ± 0.746
1.194PheCys: 1.194 ± 0.418
2.089PheAsp: 2.089 ± 0.792
3.581PheGlu: 3.581 ± 1.228
2.686PhePhe: 2.686 ± 0.907
2.686PheGly: 2.686 ± 0.495
0.298PheHis: 0.298 ± 0.162
2.387PheIle: 2.387 ± 0.364
3.879PheLys: 3.879 ± 0.809
6.864PheLeu: 6.864 ± 1.975
0.597PheMet: 0.597 ± 0.324
2.984PheAsn: 2.984 ± 1.187
0.895PhePro: 0.895 ± 0.477
2.984PheGln: 2.984 ± 0.358
1.791PheArg: 1.791 ± 0.115
2.686PheSer: 2.686 ± 0.993
3.581PheThr: 3.581 ± 0.23
2.387PheVal: 2.387 ± 1.296
1.194PheTrp: 1.194 ± 0.854
1.492PheTyr: 1.492 ± 0.81
0.0PheXaa: 0.0 ± 0.0
Gly
2.387GlyAla: 2.387 ± 0.906
0.298GlyCys: 0.298 ± 0.515
2.984GlyAsp: 2.984 ± 1.023
3.283GlyGlu: 3.283 ± 0.567
4.178GlyPhe: 4.178 ± 0.917
2.686GlyGly: 2.686 ± 0.945
0.895GlyHis: 0.895 ± 0.477
2.089GlyIle: 2.089 ± 1.134
2.089GlyLys: 2.089 ± 0.746
5.67GlyLeu: 5.67 ± 0.902
0.298GlyMet: 0.298 ± 0.438
5.073GlyAsn: 5.073 ± 1.582
1.194GlyPro: 1.194 ± 0.383
2.089GlyGln: 2.089 ± 0.898
3.283GlyArg: 3.283 ± 1.233
4.178GlySer: 4.178 ± 0.947
0.597GlyThr: 0.597 ± 0.635
3.283GlyVal: 3.283 ± 1.08
0.298GlyTrp: 0.298 ± 0.438
1.492GlyTyr: 1.492 ± 0.179
0.0GlyXaa: 0.0 ± 0.0
His
0.298HisAla: 0.298 ± 0.515
0.597HisCys: 0.597 ± 0.353
1.492HisAsp: 1.492 ± 1.683
1.194HisGlu: 1.194 ± 0.648
0.298HisPhe: 0.298 ± 0.162
0.895HisGly: 0.895 ± 0.779
0.298HisHis: 0.298 ± 0.162
1.492HisIle: 1.492 ± 0.499
1.791HisLys: 1.791 ± 0.614
3.581HisLeu: 3.581 ± 0.722
0.597HisMet: 0.597 ± 0.383
1.791HisAsn: 1.791 ± 0.589
0.895HisPro: 0.895 ± 0.932
0.895HisGln: 0.895 ± 0.486
1.194HisArg: 1.194 ± 1.444
2.089HisSer: 2.089 ± 0.565
0.597HisThr: 0.597 ± 0.635
1.194HisVal: 1.194 ± 0.418
0.0HisTrp: 0.0 ± 0.0
0.298HisTyr: 0.298 ± 0.606
0.0HisXaa: 0.0 ± 0.0
Ile
2.387IleAla: 2.387 ± 1.855
2.387IleCys: 2.387 ± 0.648
1.791IleAsp: 1.791 ± 1.059
5.073IleGlu: 5.073 ± 1.807
1.492IlePhe: 1.492 ± 0.81
2.686IleGly: 2.686 ± 0.305
0.597IleHis: 0.597 ± 0.324
2.686IleIle: 2.686 ± 1.136
5.968IleLys: 5.968 ± 1.331
5.968IleLeu: 5.968 ± 1.335
2.984IleMet: 2.984 ± 1.278
3.879IleAsn: 3.879 ± 1.228
2.089IlePro: 2.089 ± 0.402
2.984IleGln: 2.984 ± 0.917
1.194IleArg: 1.194 ± 0.854
4.476IleSer: 4.476 ± 1.089
2.984IleThr: 2.984 ± 1.493
3.581IleVal: 3.581 ± 1.11
0.298IleTrp: 0.298 ± 0.438
1.492IleTyr: 1.492 ± 0.81
0.0IleXaa: 0.0 ± 0.0
Lys
2.984LysAla: 2.984 ± 0.371
1.791LysCys: 1.791 ± 0.985
5.67LysAsp: 5.67 ± 2.015
4.476LysGlu: 4.476 ± 0.984
3.283LysPhe: 3.283 ± 0.84
3.283LysGly: 3.283 ± 0.485
2.089LysHis: 2.089 ± 0.565
5.073LysIle: 5.073 ± 1.807
4.476LysLys: 4.476 ± 2.33
10.146LysLeu: 10.146 ± 0.965
0.597LysMet: 0.597 ± 0.353
3.581LysAsn: 3.581 ± 0.722
1.791LysPro: 1.791 ± 1.076
1.791LysGln: 1.791 ± 0.614
3.581LysArg: 3.581 ± 1.324
6.267LysSer: 6.267 ± 1.096
5.073LysThr: 5.073 ± 0.556
5.372LysVal: 5.372 ± 0.526
0.895LysTrp: 0.895 ± 0.486
1.791LysTyr: 1.791 ± 0.614
0.0LysXaa: 0.0 ± 0.0
Leu
5.67LeuAla: 5.67 ± 0.422
3.879LeuCys: 3.879 ± 1.293
8.057LeuAsp: 8.057 ± 1.447
8.057LeuGlu: 8.057 ± 1.132
4.775LeuPhe: 4.775 ± 1.672
7.162LeuGly: 7.162 ± 1.704
2.686LeuHis: 2.686 ± 0.907
5.968LeuIle: 5.968 ± 1.998
9.549LeuLys: 9.549 ± 1.668
15.816LeuLeu: 15.816 ± 1.003
3.283LeuMet: 3.283 ± 1.118
6.864LeuAsn: 6.864 ± 1.842
3.581LeuPro: 3.581 ± 1.251
3.581LeuGln: 3.581 ± 0.722
7.759LeuArg: 7.759 ± 1.041
14.324LeuSer: 14.324 ± 2.894
4.476LeuThr: 4.476 ± 0.955
8.654LeuVal: 8.654 ± 2.105
1.194LeuTrp: 1.194 ± 0.418
3.581LeuTyr: 3.581 ± 0.815
0.0LeuXaa: 0.0 ± 0.0
Met
1.492MetAla: 1.492 ± 0.179
0.298MetCys: 0.298 ± 0.162
1.194MetAsp: 1.194 ± 0.383
0.298MetGlu: 0.298 ± 0.162
1.492MetPhe: 1.492 ± 0.663
2.984MetGly: 2.984 ± 0.632
0.0MetHis: 0.0 ± 0.0
2.387MetIle: 2.387 ± 0.906
2.984MetLys: 2.984 ± 0.371
3.283MetLeu: 3.283 ± 2.449
0.597MetMet: 0.597 ± 0.427
0.0MetAsn: 0.0 ± 0.0
0.298MetPro: 0.298 ± 0.515
0.0MetGln: 0.0 ± 0.0
1.194MetArg: 1.194 ± 0.648
3.581MetSer: 3.581 ± 0.62
1.492MetThr: 1.492 ± 0.487
1.791MetVal: 1.791 ± 0.115
0.597MetTrp: 0.597 ± 0.324
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.387AsnAla: 2.387 ± 1.187
1.194AsnCys: 1.194 ± 1.311
2.387AsnAsp: 2.387 ± 1.075
2.686AsnGlu: 2.686 ± 0.907
2.984AsnPhe: 2.984 ± 0.973
2.686AsnGly: 2.686 ± 0.305
1.791AsnHis: 1.791 ± 1.554
2.686AsnIle: 2.686 ± 0.986
4.178AsnLys: 4.178 ± 1.258
10.445AsnLeu: 10.445 ± 0.887
0.895AsnMet: 0.895 ± 0.963
2.089AsnAsn: 2.089 ± 0.216
2.387AsnPro: 2.387 ± 0.767
2.686AsnGln: 2.686 ± 0.47
2.089AsnArg: 2.089 ± 0.402
3.283AsnSer: 3.283 ± 0.567
4.476AsnThr: 4.476 ± 1.97
2.089AsnVal: 2.089 ± 0.402
0.0AsnTrp: 0.0 ± 0.0
1.791AsnTyr: 1.791 ± 0.954
0.0AsnXaa: 0.0 ± 0.0
Pro
1.194ProAla: 1.194 ± 0.706
0.298ProCys: 0.298 ± 0.515
2.387ProAsp: 2.387 ± 0.364
2.089ProGlu: 2.089 ± 0.949
1.492ProPhe: 1.492 ± 0.81
1.492ProGly: 1.492 ± 1.185
1.492ProHis: 1.492 ± 1.112
1.492ProIle: 1.492 ± 0.802
2.984ProLys: 2.984 ± 0.371
2.686ProLeu: 2.686 ± 0.839
0.0ProMet: 0.0 ± 0.0
1.194ProAsn: 1.194 ± 0.322
0.597ProPro: 0.597 ± 0.635
1.492ProGln: 1.492 ± 1.128
1.194ProArg: 1.194 ± 0.854
3.283ProSer: 3.283 ± 1.484
3.283ProThr: 3.283 ± 1.377
2.686ProVal: 2.686 ± 1.634
0.0ProTrp: 0.0 ± 0.0
1.492ProTyr: 1.492 ± 0.663
0.0ProXaa: 0.0 ± 0.0
Gln
2.089GlnAla: 2.089 ± 0.849
0.895GlnCys: 0.895 ± 0.39
2.686GlnAsp: 2.686 ± 1.059
2.387GlnGlu: 2.387 ± 0.494
2.089GlnPhe: 2.089 ± 0.216
2.686GlnGly: 2.686 ± 1.43
0.0GlnHis: 0.0 ± 0.0
2.686GlnIle: 2.686 ± 0.305
2.089GlnLys: 2.089 ± 0.758
3.283GlnLeu: 3.283 ± 0.577
1.791GlnMet: 1.791 ± 0.682
0.895GlnAsn: 0.895 ± 0.39
1.791GlnPro: 1.791 ± 1.918
0.597GlnGln: 0.597 ± 0.353
2.387GlnArg: 2.387 ± 0.364
4.178GlnSer: 4.178 ± 1.762
1.194GlnThr: 1.194 ± 0.322
2.089GlnVal: 2.089 ± 1.478
0.0GlnTrp: 0.0 ± 0.0
0.298GlnTyr: 0.298 ± 0.606
0.0GlnXaa: 0.0 ± 0.0
Arg
1.791ArgAla: 1.791 ± 0.614
1.791ArgCys: 1.791 ± 0.985
1.791ArgAsp: 1.791 ± 0.616
3.581ArgGlu: 3.581 ± 1.012
1.492ArgPhe: 1.492 ± 0.81
2.387ArgGly: 2.387 ± 1.296
1.492ArgHis: 1.492 ± 0.755
1.194ArgIle: 1.194 ± 0.322
2.984ArgLys: 2.984 ± 0.662
6.565ArgLeu: 6.565 ± 0.446
0.597ArgMet: 0.597 ± 0.324
2.984ArgAsn: 2.984 ± 0.358
1.194ArgPro: 1.194 ± 0.383
1.492ArgGln: 1.492 ± 1.214
2.984ArgArg: 2.984 ± 1.212
4.476ArgSer: 4.476 ± 1.387
1.791ArgThr: 1.791 ± 0.662
3.283ArgVal: 3.283 ± 0.84
1.194ArgTrp: 1.194 ± 0.322
2.387ArgTyr: 2.387 ± 0.888
0.0ArgXaa: 0.0 ± 0.0
Ser
2.686SerAla: 2.686 ± 2.229
2.089SerCys: 2.089 ± 0.792
5.968SerAsp: 5.968 ± 1.098
6.267SerGlu: 6.267 ± 1.699
4.178SerPhe: 4.178 ± 0.432
2.984SerGly: 2.984 ± 0.662
1.791SerHis: 1.791 ± 1.076
3.879SerIle: 3.879 ± 1.654
7.46SerLys: 7.46 ± 2.87
10.146SerLeu: 10.146 ± 1.367
2.387SerMet: 2.387 ± 1.296
5.372SerAsn: 5.372 ± 1.645
2.686SerPro: 2.686 ± 0.521
2.089SerGln: 2.089 ± 2.342
4.775SerArg: 4.775 ± 1.812
6.565SerSer: 6.565 ± 1.734
4.178SerThr: 4.178 ± 0.322
7.46SerVal: 7.46 ± 1.727
0.597SerTrp: 0.597 ± 0.353
3.581SerTyr: 3.581 ± 1.001
0.0SerXaa: 0.0 ± 0.0
Thr
1.194ThrAla: 1.194 ± 0.322
0.597ThrCys: 0.597 ± 0.324
2.089ThrAsp: 2.089 ± 0.402
3.581ThrGlu: 3.581 ± 0.627
2.089ThrPhe: 2.089 ± 0.758
1.791ThrGly: 1.791 ± 0.115
1.194ThrHis: 1.194 ± 0.927
5.073ThrIle: 5.073 ± 1.582
4.476ThrLys: 4.476 ± 1.3
6.267ThrLeu: 6.267 ± 2.153
1.791ThrMet: 1.791 ± 1.039
1.791ThrAsn: 1.791 ± 1.013
2.686ThrPro: 2.686 ± 0.986
0.895ThrGln: 0.895 ± 0.779
1.791ThrArg: 1.791 ± 0.115
5.968ThrSer: 5.968 ± 0.907
2.686ThrThr: 2.686 ± 1.531
2.387ThrVal: 2.387 ± 1.382
1.492ThrTrp: 1.492 ± 2.054
0.597ThrTyr: 0.597 ± 0.324
0.0ThrXaa: 0.0 ± 0.0
Val
2.686ValAla: 2.686 ± 0.861
1.492ValCys: 1.492 ± 0.81
4.178ValAsp: 4.178 ± 0.746
3.283ValGlu: 3.283 ± 0.532
2.089ValPhe: 2.089 ± 1.224
4.178ValGly: 4.178 ± 0.746
1.194ValHis: 1.194 ± 0.418
1.791ValIle: 1.791 ± 0.115
6.565ValLys: 6.565 ± 1.248
6.565ValLeu: 6.565 ± 1.342
0.895ValMet: 0.895 ± 0.39
5.67ValAsn: 5.67 ± 2.821
2.387ValPro: 2.387 ± 0.814
2.387ValGln: 2.387 ± 0.99
3.283ValArg: 3.283 ± 1.317
6.864ValSer: 6.864 ± 2.52
2.686ValThr: 2.686 ± 0.47
5.372ValVal: 5.372 ± 1.987
0.597ValTrp: 0.597 ± 0.353
1.194ValTyr: 1.194 ± 0.383
0.0ValXaa: 0.0 ± 0.0
Trp
0.597TrpAla: 0.597 ± 0.324
0.298TrpCys: 0.298 ± 0.515
0.597TrpAsp: 0.597 ± 0.353
0.298TrpGlu: 0.298 ± 0.438
0.597TrpPhe: 0.597 ± 0.534
0.298TrpGly: 0.298 ± 0.162
0.597TrpHis: 0.597 ± 0.427
1.194TrpIle: 1.194 ± 0.927
0.895TrpLys: 0.895 ± 0.39
1.194TrpLeu: 1.194 ± 0.648
0.597TrpMet: 0.597 ± 1.03
0.0TrpAsn: 0.0 ± 0.0
0.597TrpPro: 0.597 ± 0.353
0.0TrpGln: 0.0 ± 0.0
0.298TrpArg: 0.298 ± 0.162
1.194TrpSer: 1.194 ± 0.322
0.597TrpThr: 0.597 ± 0.635
0.895TrpVal: 0.895 ± 0.39
0.0TrpTrp: 0.0 ± 0.0
0.597TrpTyr: 0.597 ± 0.427
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.492TyrAla: 1.492 ± 0.81
1.492TyrCys: 1.492 ± 0.802
2.089TyrAsp: 2.089 ± 0.746
1.492TyrGlu: 1.492 ± 0.665
0.895TyrPhe: 0.895 ± 0.39
0.597TyrGly: 0.597 ± 0.534
0.298TyrHis: 0.298 ± 0.162
2.089TyrIle: 2.089 ± 0.949
1.492TyrLys: 1.492 ± 0.487
3.283TyrLeu: 3.283 ± 0.532
0.298TyrMet: 0.298 ± 0.162
1.492TyrAsn: 1.492 ± 0.487
0.895TyrPro: 0.895 ± 0.932
1.791TyrGln: 1.791 ± 0.589
0.895TyrArg: 0.895 ± 0.331
2.686TyrSer: 2.686 ± 1.457
1.791TyrThr: 1.791 ± 0.115
2.089TyrVal: 2.089 ± 0.746
0.0TyrTrp: 0.0 ± 0.0
0.597TyrTyr: 0.597 ± 0.427
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3352 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski