Amino acid dipepetide frequency for Chicken associated cyclovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.917AlaAla: 5.917 ± 1.555
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
0.0AlaGlu: 0.0 ± 0.0
1.972AlaPhe: 1.972 ± 1.355
1.972AlaGly: 1.972 ± 1.355
0.0AlaHis: 0.0 ± 0.0
1.972AlaIle: 1.972 ± 1.455
1.972AlaLys: 1.972 ± 1.455
3.945AlaLeu: 3.945 ± 2.91
1.972AlaMet: 1.972 ± 1.455
1.972AlaAsn: 1.972 ± 1.355
1.972AlaPro: 1.972 ± 1.355
3.945AlaGln: 3.945 ± 2.71
3.945AlaArg: 3.945 ± 0.1
1.972AlaSer: 1.972 ± 1.455
7.89AlaThr: 7.89 ± 2.61
1.972AlaVal: 1.972 ± 1.355
0.0AlaTrp: 0.0 ± 0.0
3.945AlaTyr: 3.945 ± 0.1
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.972CysAsp: 1.972 ± 1.355
1.972CysGlu: 1.972 ± 1.455
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.972CysMet: 1.972 ± 1.455
1.972CysAsn: 1.972 ± 1.455
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.945CysSer: 3.945 ± 2.91
0.0CysThr: 0.0 ± 0.0
1.972CysVal: 1.972 ± 1.455
0.0CysTrp: 0.0 ± 0.0
3.945CysTyr: 3.945 ± 2.71
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
3.945AspCys: 3.945 ± 2.71
5.917AspAsp: 5.917 ± 1.255
5.917AspGlu: 5.917 ± 1.555
3.945AspPhe: 3.945 ± 2.91
3.945AspGly: 3.945 ± 2.91
0.0AspHis: 0.0 ± 0.0
3.945AspIle: 3.945 ± 0.1
3.945AspLys: 3.945 ± 0.1
3.945AspLeu: 3.945 ± 0.1
0.0AspMet: 0.0 ± 0.0
5.917AspAsn: 5.917 ± 1.555
0.0AspPro: 0.0 ± 0.0
1.972AspGln: 1.972 ± 1.355
3.945AspArg: 3.945 ± 2.91
0.0AspSer: 0.0 ± 0.0
1.972AspThr: 1.972 ± 1.355
1.972AspVal: 1.972 ± 1.455
1.972AspTrp: 1.972 ± 1.455
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
1.972GluCys: 1.972 ± 1.455
0.0GluAsp: 0.0 ± 0.0
1.972GluGlu: 1.972 ± 1.455
0.0GluPhe: 0.0 ± 0.0
3.945GluGly: 3.945 ± 0.1
3.945GluHis: 3.945 ± 2.91
5.917GluIle: 5.917 ± 1.555
3.945GluLys: 3.945 ± 0.1
5.917GluLeu: 5.917 ± 1.555
0.0GluMet: 0.0 ± 0.0
3.945GluAsn: 3.945 ± 0.1
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
1.972GluArg: 1.972 ± 1.455
3.945GluSer: 3.945 ± 0.1
0.0GluThr: 0.0 ± 0.0
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
1.972GluTyr: 1.972 ± 1.355
0.0GluXaa: 0.0 ± 0.0
Phe
1.972PheAla: 1.972 ± 1.355
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
0.0PheGlu: 0.0 ± 0.0
3.945PhePhe: 3.945 ± 0.1
3.945PheGly: 3.945 ± 0.1
0.0PheHis: 0.0 ± 0.0
1.972PheIle: 1.972 ± 1.455
0.0PheLys: 0.0 ± 0.0
3.945PheLeu: 3.945 ± 2.91
3.945PheMet: 3.945 ± 2.71
1.972PheAsn: 1.972 ± 1.455
5.917PhePro: 5.917 ± 4.065
3.945PheGln: 3.945 ± 0.1
3.945PheArg: 3.945 ± 2.71
1.972PheSer: 1.972 ± 1.355
5.917PheThr: 5.917 ± 1.255
1.972PheVal: 1.972 ± 1.355
3.945PheTrp: 3.945 ± 0.1
5.917PheTyr: 5.917 ± 1.555
0.0PheXaa: 0.0 ± 0.0
Gly
9.862GlyAla: 9.862 ± 1.654
1.972GlyCys: 1.972 ± 1.455
1.972GlyAsp: 1.972 ± 1.455
1.972GlyGlu: 1.972 ± 1.455
1.972GlyPhe: 1.972 ± 1.455
3.945GlyGly: 3.945 ± 0.1
3.945GlyHis: 3.945 ± 2.91
1.972GlyIle: 1.972 ± 1.455
5.917GlyLys: 5.917 ± 1.555
3.945GlyLeu: 3.945 ± 0.1
0.0GlyMet: 0.0 ± 0.0
0.0GlyAsn: 0.0 ± 0.0
0.0GlyPro: 0.0 ± 0.0
5.917GlyGln: 5.917 ± 1.255
7.89GlyArg: 7.89 ± 0.2
7.89GlySer: 7.89 ± 3.009
7.89GlyThr: 7.89 ± 0.2
3.945GlyVal: 3.945 ± 2.71
3.945GlyTrp: 3.945 ± 0.1
1.972GlyTyr: 1.972 ± 1.455
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.972HisAsp: 1.972 ± 1.455
3.945HisGlu: 3.945 ± 0.1
0.0HisPhe: 0.0 ± 0.0
1.972HisGly: 1.972 ± 1.455
0.0HisHis: 0.0 ± 0.0
3.945HisIle: 3.945 ± 2.91
0.0HisLys: 0.0 ± 0.0
1.972HisLeu: 1.972 ± 1.455
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.972HisPro: 1.972 ± 1.455
1.972HisGln: 1.972 ± 1.355
3.945HisArg: 3.945 ± 2.91
1.972HisSer: 1.972 ± 1.455
1.972HisThr: 1.972 ± 1.455
3.945HisVal: 3.945 ± 0.1
0.0HisTrp: 0.0 ± 0.0
1.972HisTyr: 1.972 ± 1.355
0.0HisXaa: 0.0 ± 0.0
Ile
1.972IleAla: 1.972 ± 1.355
3.945IleCys: 3.945 ± 2.91
9.862IleAsp: 9.862 ± 1.156
3.945IleGlu: 3.945 ± 2.91
0.0IlePhe: 0.0 ± 0.0
1.972IleGly: 1.972 ± 1.455
1.972IleHis: 1.972 ± 1.455
1.972IleIle: 1.972 ± 1.455
5.917IleLys: 5.917 ± 4.364
3.945IleLeu: 3.945 ± 0.1
0.0IleMet: 0.0 ± 0.0
1.972IleAsn: 1.972 ± 1.355
1.972IlePro: 1.972 ± 1.455
3.945IleGln: 3.945 ± 0.1
3.945IleArg: 3.945 ± 0.1
3.945IleSer: 3.945 ± 0.1
11.834IleThr: 11.834 ± 2.511
1.972IleVal: 1.972 ± 1.455
0.0IleTrp: 0.0 ± 0.0
7.89IleTyr: 7.89 ± 2.61
0.0IleXaa: 0.0 ± 0.0
Lys
1.972LysAla: 1.972 ± 1.455
0.0LysCys: 0.0 ± 0.0
1.972LysAsp: 1.972 ± 1.455
1.972LysGlu: 1.972 ± 1.455
0.0LysPhe: 0.0 ± 0.0
5.917LysGly: 5.917 ± 1.555
1.972LysHis: 1.972 ± 1.455
9.862LysIle: 9.862 ± 3.965
3.945LysLys: 3.945 ± 0.1
1.972LysLeu: 1.972 ± 1.355
1.972LysMet: 1.972 ± 1.355
0.0LysAsn: 0.0 ± 0.0
3.945LysPro: 3.945 ± 0.1
0.0LysGln: 0.0 ± 0.0
5.917LysArg: 5.917 ± 1.555
5.917LysSer: 5.917 ± 1.555
5.917LysThr: 5.917 ± 1.255
1.972LysVal: 1.972 ± 1.455
1.972LysTrp: 1.972 ± 1.455
1.972LysTyr: 1.972 ± 1.455
0.0LysXaa: 0.0 ± 0.0
Leu
5.917LeuAla: 5.917 ± 1.555
0.0LeuCys: 0.0 ± 0.0
1.972LeuAsp: 1.972 ± 1.355
1.972LeuGlu: 1.972 ± 1.355
3.945LeuPhe: 3.945 ± 2.71
1.972LeuGly: 1.972 ± 1.455
3.945LeuHis: 3.945 ± 0.1
1.972LeuIle: 1.972 ± 1.455
3.945LeuLys: 3.945 ± 0.1
1.972LeuLeu: 1.972 ± 1.455
3.945LeuMet: 3.945 ± 2.287
3.945LeuAsn: 3.945 ± 2.71
0.0LeuPro: 0.0 ± 0.0
1.972LeuGln: 1.972 ± 1.355
7.89LeuArg: 7.89 ± 3.009
3.945LeuSer: 3.945 ± 2.71
0.0LeuThr: 0.0 ± 0.0
3.945LeuVal: 3.945 ± 0.1
1.972LeuTrp: 1.972 ± 1.455
1.972LeuTyr: 1.972 ± 1.355
0.0LeuXaa: 0.0 ± 0.0
Met
1.972MetAla: 1.972 ± 1.355
0.0MetCys: 0.0 ± 0.0
1.972MetAsp: 1.972 ± 1.355
0.0MetGlu: 0.0 ± 0.0
1.972MetPhe: 1.972 ± 1.455
1.972MetGly: 1.972 ± 1.455
0.0MetHis: 0.0 ± 0.0
1.972MetIle: 1.972 ± 1.455
0.0MetLys: 0.0 ± 0.0
1.972MetLeu: 1.972 ± 1.455
0.0MetMet: 0.0 ± 0.966
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.972MetArg: 1.972 ± 1.355
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.945AsnAla: 3.945 ± 2.71
0.0AsnCys: 0.0 ± 0.0
3.945AsnAsp: 3.945 ± 2.91
0.0AsnGlu: 0.0 ± 0.0
3.945AsnPhe: 3.945 ± 2.71
3.945AsnGly: 3.945 ± 0.1
3.945AsnHis: 3.945 ± 2.91
1.972AsnIle: 1.972 ± 1.355
7.89AsnLys: 7.89 ± 0.2
1.972AsnLeu: 1.972 ± 1.355
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
0.0AsnPro: 0.0 ± 0.0
3.945AsnGln: 3.945 ± 2.91
0.0AsnArg: 0.0 ± 0.0
3.945AsnSer: 3.945 ± 2.71
1.972AsnThr: 1.972 ± 1.355
1.972AsnVal: 1.972 ± 1.355
1.972AsnTrp: 1.972 ± 1.455
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
1.972ProGlu: 1.972 ± 1.355
0.0ProPhe: 0.0 ± 0.0
1.972ProGly: 1.972 ± 1.355
3.945ProHis: 3.945 ± 2.91
1.972ProIle: 1.972 ± 1.355
1.972ProLys: 1.972 ± 1.355
1.972ProLeu: 1.972 ± 1.355
0.0ProMet: 0.0 ± 0.0
1.972ProAsn: 1.972 ± 1.355
0.0ProPro: 0.0 ± 0.0
5.917ProGln: 5.917 ± 1.555
5.917ProArg: 5.917 ± 1.255
0.0ProSer: 0.0 ± 0.0
1.972ProThr: 1.972 ± 1.355
1.972ProVal: 1.972 ± 1.355
0.0ProTrp: 0.0 ± 0.0
1.972ProTyr: 1.972 ± 1.455
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.972GlnAsp: 1.972 ± 1.455
0.0GlnGlu: 0.0 ± 0.0
7.89GlnPhe: 7.89 ± 2.61
3.945GlnGly: 3.945 ± 2.91
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.972GlnLys: 1.972 ± 1.455
3.945GlnLeu: 3.945 ± 2.71
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.972GlnPro: 1.972 ± 1.355
1.972GlnGln: 1.972 ± 1.355
0.0GlnArg: 0.0 ± 0.0
5.917GlnSer: 5.917 ± 4.065
1.972GlnThr: 1.972 ± 1.455
1.972GlnVal: 1.972 ± 1.355
0.0GlnTrp: 0.0 ± 0.0
3.945GlnTyr: 3.945 ± 0.1
0.0GlnXaa: 0.0 ± 0.0
Arg
3.945ArgAla: 3.945 ± 0.1
1.972ArgCys: 1.972 ± 1.455
1.972ArgAsp: 1.972 ± 1.455
0.0ArgGlu: 0.0 ± 0.0
5.917ArgPhe: 5.917 ± 1.255
3.945ArgGly: 3.945 ± 0.1
3.945ArgHis: 3.945 ± 2.71
5.917ArgIle: 5.917 ± 4.364
1.972ArgLys: 1.972 ± 1.355
5.917ArgLeu: 5.917 ± 1.255
0.0ArgMet: 0.0 ± 0.0
3.945ArgAsn: 3.945 ± 2.91
1.972ArgPro: 1.972 ± 1.355
1.972ArgGln: 1.972 ± 1.355
27.613ArgArg: 27.613 ± 10.541
3.945ArgSer: 3.945 ± 0.1
1.972ArgThr: 1.972 ± 1.355
7.89ArgVal: 7.89 ± 0.2
0.0ArgTrp: 0.0 ± 0.0
9.862ArgTyr: 9.862 ± 1.654
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
1.972SerAsp: 1.972 ± 1.455
0.0SerGlu: 0.0 ± 0.0
7.89SerPhe: 7.89 ± 2.61
5.917SerGly: 5.917 ± 4.364
0.0SerHis: 0.0 ± 0.0
9.862SerIle: 9.862 ± 1.156
3.945SerLys: 3.945 ± 0.1
3.945SerLeu: 3.945 ± 0.1
0.0SerMet: 0.0 ± 0.0
5.917SerAsn: 5.917 ± 1.555
3.945SerPro: 3.945 ± 0.1
0.0SerGln: 0.0 ± 0.0
5.917SerArg: 5.917 ± 1.255
3.945SerSer: 3.945 ± 2.71
5.917SerThr: 5.917 ± 4.065
1.972SerVal: 1.972 ± 1.355
1.972SerTrp: 1.972 ± 1.455
3.945SerTyr: 3.945 ± 2.71
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
0.0ThrCys: 0.0 ± 0.0
1.972ThrAsp: 1.972 ± 1.455
3.945ThrGlu: 3.945 ± 0.1
3.945ThrPhe: 3.945 ± 2.71
11.834ThrGly: 11.834 ± 0.299
1.972ThrHis: 1.972 ± 1.355
3.945ThrIle: 3.945 ± 2.71
3.945ThrLys: 3.945 ± 0.1
1.972ThrLeu: 1.972 ± 1.355
0.0ThrMet: 0.0 ± 0.0
3.945ThrAsn: 3.945 ± 2.71
3.945ThrPro: 3.945 ± 0.1
0.0ThrGln: 0.0 ± 0.0
3.945ThrArg: 3.945 ± 2.71
9.862ThrSer: 9.862 ± 1.156
3.945ThrThr: 3.945 ± 2.71
1.972ThrVal: 1.972 ± 1.355
0.0ThrTrp: 0.0 ± 0.0
1.972ThrTyr: 1.972 ± 1.355
0.0ThrXaa: 0.0 ± 0.0
Val
5.917ValAla: 5.917 ± 1.255
0.0ValCys: 0.0 ± 0.0
3.945ValAsp: 3.945 ± 0.1
3.945ValGlu: 3.945 ± 2.91
3.945ValPhe: 3.945 ± 2.91
5.917ValGly: 5.917 ± 4.065
0.0ValHis: 0.0 ± 0.0
3.945ValIle: 3.945 ± 0.1
0.0ValLys: 0.0 ± 0.0
1.972ValLeu: 1.972 ± 1.355
0.0ValMet: 0.0 ± 0.0
3.945ValAsn: 3.945 ± 2.71
3.945ValPro: 3.945 ± 2.71
0.0ValGln: 0.0 ± 0.0
1.972ValArg: 1.972 ± 1.355
0.0ValSer: 0.0 ± 0.0
0.0ValThr: 0.0 ± 0.0
1.972ValVal: 1.972 ± 1.355
1.972ValTrp: 1.972 ± 1.355
3.945ValTyr: 3.945 ± 0.1
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.972TrpAsp: 1.972 ± 1.455
1.972TrpGlu: 1.972 ± 1.455
1.972TrpPhe: 1.972 ± 1.455
1.972TrpGly: 1.972 ± 1.455
0.0TrpHis: 0.0 ± 0.0
1.972TrpIle: 1.972 ± 1.455
3.945TrpLys: 3.945 ± 0.1
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.972TrpSer: 1.972 ± 1.355
0.0TrpThr: 0.0 ± 0.0
1.972TrpVal: 1.972 ± 1.355
1.972TrpTrp: 1.972 ± 1.455
1.972TrpTyr: 1.972 ± 1.455
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.945TyrAla: 3.945 ± 0.1
3.945TyrCys: 3.945 ± 0.1
7.89TyrAsp: 7.89 ± 0.2
3.945TyrGlu: 3.945 ± 2.71
1.972TyrPhe: 1.972 ± 1.355
5.917TyrGly: 5.917 ± 1.555
1.972TyrHis: 1.972 ± 1.455
7.89TyrIle: 7.89 ± 0.2
3.945TyrLys: 3.945 ± 0.1
1.972TyrLeu: 1.972 ± 1.355
0.0TyrMet: 0.0 ± 0.0
3.945TyrAsn: 3.945 ± 0.1
1.972TyrPro: 1.972 ± 1.455
0.0TyrGln: 0.0 ± 0.0
3.945TyrArg: 3.945 ± 0.1
1.972TyrSer: 1.972 ± 1.355
1.972TyrThr: 1.972 ± 1.355
1.972TyrVal: 1.972 ± 1.355
0.0TyrTrp: 0.0 ± 0.0
5.917TyrTyr: 5.917 ± 1.255
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (508 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski