Amino acid dipepetide frequency for Sanxia picorna-like virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.101AlaAla: 7.101 ± 0.0
1.291AlaCys: 1.291 ± 0.0
2.905AlaAsp: 2.905 ± 0.0
4.519AlaGlu: 4.519 ± 0.0
4.842AlaPhe: 4.842 ± 0.0
3.228AlaGly: 3.228 ± 0.0
2.26AlaHis: 2.26 ± 0.0
2.905AlaIle: 2.905 ± 0.0
2.26AlaLys: 2.26 ± 0.0
3.228AlaLeu: 3.228 ± 0.0
2.26AlaMet: 2.26 ± 0.0
2.582AlaAsn: 2.582 ± 0.0
5.81AlaPro: 5.81 ± 0.0
1.614AlaGln: 1.614 ± 0.0
3.228AlaArg: 3.228 ± 0.0
6.779AlaSer: 6.779 ± 0.0
3.873AlaThr: 3.873 ± 0.0
5.487AlaVal: 5.487 ± 0.0
2.26AlaTrp: 2.26 ± 0.0
1.937AlaTyr: 1.937 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.291CysAla: 1.291 ± 0.0
0.323CysCys: 0.323 ± 0.0
0.646CysAsp: 0.646 ± 0.0
1.614CysGlu: 1.614 ± 0.0
1.291CysPhe: 1.291 ± 0.0
1.937CysGly: 1.937 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.646CysIle: 0.646 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.291CysLeu: 1.291 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.323CysAsn: 0.323 ± 0.0
1.614CysPro: 1.614 ± 0.0
0.968CysGln: 0.968 ± 0.0
1.291CysArg: 1.291 ± 0.0
0.968CysSer: 0.968 ± 0.0
0.968CysThr: 0.968 ± 0.0
0.968CysVal: 0.968 ± 0.0
0.968CysTrp: 0.968 ± 0.0
0.968CysTyr: 0.968 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.614AspAla: 1.614 ± 0.0
1.291AspCys: 1.291 ± 0.0
3.228AspAsp: 3.228 ± 0.0
1.937AspGlu: 1.937 ± 0.0
2.26AspPhe: 2.26 ± 0.0
4.196AspGly: 4.196 ± 0.0
0.968AspHis: 0.968 ± 0.0
1.937AspIle: 1.937 ± 0.0
2.905AspLys: 2.905 ± 0.0
4.519AspLeu: 4.519 ± 0.0
0.968AspMet: 0.968 ± 0.0
1.291AspAsn: 1.291 ± 0.0
4.519AspPro: 4.519 ± 0.0
0.968AspGln: 0.968 ± 0.0
0.0AspArg: 0.0 ± 0.0
4.196AspSer: 4.196 ± 0.0
3.228AspThr: 3.228 ± 0.0
2.582AspVal: 2.582 ± 0.0
0.646AspTrp: 0.646 ± 0.0
2.26AspTyr: 2.26 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.165GluAla: 5.165 ± 0.0
0.0GluCys: 0.0 ± 0.0
3.228GluAsp: 3.228 ± 0.0
3.551GluGlu: 3.551 ± 0.0
3.551GluPhe: 3.551 ± 0.0
2.905GluGly: 2.905 ± 0.0
1.614GluHis: 1.614 ± 0.0
3.228GluIle: 3.228 ± 0.0
2.582GluLys: 2.582 ± 0.0
2.905GluLeu: 2.905 ± 0.0
1.614GluMet: 1.614 ± 0.0
3.228GluAsn: 3.228 ± 0.0
1.937GluPro: 1.937 ± 0.0
1.614GluGln: 1.614 ± 0.0
1.937GluArg: 1.937 ± 0.0
6.456GluSer: 6.456 ± 0.0
3.873GluThr: 3.873 ± 0.0
2.582GluVal: 2.582 ± 0.0
1.614GluTrp: 1.614 ± 0.0
1.614GluTyr: 1.614 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.228PheAla: 3.228 ± 0.0
1.614PheCys: 1.614 ± 0.0
1.614PheAsp: 1.614 ± 0.0
2.26PheGlu: 2.26 ± 0.0
3.873PhePhe: 3.873 ± 0.0
3.873PheGly: 3.873 ± 0.0
1.614PheHis: 1.614 ± 0.0
2.582PheIle: 2.582 ± 0.0
2.26PheLys: 2.26 ± 0.0
5.487PheLeu: 5.487 ± 0.0
0.646PheMet: 0.646 ± 0.0
0.968PheAsn: 0.968 ± 0.0
2.26PhePro: 2.26 ± 0.0
2.26PheGln: 2.26 ± 0.0
3.873PheArg: 3.873 ± 0.0
5.165PheSer: 5.165 ± 0.0
1.937PheThr: 1.937 ± 0.0
3.551PheVal: 3.551 ± 0.0
1.291PheTrp: 1.291 ± 0.0
1.937PheTyr: 1.937 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.519GlyAla: 4.519 ± 0.0
0.968GlyCys: 0.968 ± 0.0
2.905GlyAsp: 2.905 ± 0.0
5.487GlyGlu: 5.487 ± 0.0
3.873GlyPhe: 3.873 ± 0.0
4.196GlyGly: 4.196 ± 0.0
1.291GlyHis: 1.291 ± 0.0
2.905GlyIle: 2.905 ± 0.0
3.228GlyLys: 3.228 ± 0.0
5.81GlyLeu: 5.81 ± 0.0
2.26GlyMet: 2.26 ± 0.0
3.551GlyAsn: 3.551 ± 0.0
2.905GlyPro: 2.905 ± 0.0
0.646GlyGln: 0.646 ± 0.0
2.26GlyArg: 2.26 ± 0.0
2.905GlySer: 2.905 ± 0.0
2.582GlyThr: 2.582 ± 0.0
3.873GlyVal: 3.873 ± 0.0
1.291GlyTrp: 1.291 ± 0.0
3.551GlyTyr: 3.551 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.291HisAla: 1.291 ± 0.0
1.614HisCys: 1.614 ± 0.0
0.646HisAsp: 0.646 ± 0.0
1.291HisGlu: 1.291 ± 0.0
1.614HisPhe: 1.614 ± 0.0
0.323HisGly: 0.323 ± 0.0
0.646HisHis: 0.646 ± 0.0
1.291HisIle: 1.291 ± 0.0
0.968HisLys: 0.968 ± 0.0
2.26HisLeu: 2.26 ± 0.0
0.646HisMet: 0.646 ± 0.0
0.646HisAsn: 0.646 ± 0.0
0.968HisPro: 0.968 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.291HisArg: 1.291 ± 0.0
1.614HisSer: 1.614 ± 0.0
2.26HisThr: 2.26 ± 0.0
3.228HisVal: 3.228 ± 0.0
0.323HisTrp: 0.323 ± 0.0
0.646HisTyr: 0.646 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.228IleAla: 3.228 ± 0.0
0.646IleCys: 0.646 ± 0.0
3.228IleAsp: 3.228 ± 0.0
4.519IleGlu: 4.519 ± 0.0
1.614IlePhe: 1.614 ± 0.0
3.873IleGly: 3.873 ± 0.0
0.646IleHis: 0.646 ± 0.0
1.937IleIle: 1.937 ± 0.0
0.968IleLys: 0.968 ± 0.0
5.81IleLeu: 5.81 ± 0.0
1.291IleMet: 1.291 ± 0.0
0.968IleAsn: 0.968 ± 0.0
3.228IlePro: 3.228 ± 0.0
1.291IleGln: 1.291 ± 0.0
3.551IleArg: 3.551 ± 0.0
8.07IleSer: 8.07 ± 0.0
2.905IleThr: 2.905 ± 0.0
1.614IleVal: 1.614 ± 0.0
0.323IleTrp: 0.323 ± 0.0
1.614IleTyr: 1.614 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.905LysAla: 2.905 ± 0.0
1.614LysCys: 1.614 ± 0.0
2.905LysAsp: 2.905 ± 0.0
1.937LysGlu: 1.937 ± 0.0
1.291LysPhe: 1.291 ± 0.0
2.26LysGly: 2.26 ± 0.0
1.614LysHis: 1.614 ± 0.0
3.551LysIle: 3.551 ± 0.0
0.646LysLys: 0.646 ± 0.0
4.519LysLeu: 4.519 ± 0.0
0.646LysMet: 0.646 ± 0.0
1.291LysAsn: 1.291 ± 0.0
3.873LysPro: 3.873 ± 0.0
1.614LysGln: 1.614 ± 0.0
2.905LysArg: 2.905 ± 0.0
3.228LysSer: 3.228 ± 0.0
2.582LysThr: 2.582 ± 0.0
3.551LysVal: 3.551 ± 0.0
0.968LysTrp: 0.968 ± 0.0
0.646LysTyr: 0.646 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.81LeuAla: 5.81 ± 0.0
1.614LeuCys: 1.614 ± 0.0
7.424LeuAsp: 7.424 ± 0.0
5.165LeuGlu: 5.165 ± 0.0
5.81LeuPhe: 5.81 ± 0.0
5.487LeuGly: 5.487 ± 0.0
3.551LeuHis: 3.551 ± 0.0
3.228LeuIle: 3.228 ± 0.0
8.715LeuLys: 8.715 ± 0.0
6.133LeuLeu: 6.133 ± 0.0
1.614LeuMet: 1.614 ± 0.0
1.937LeuAsn: 1.937 ± 0.0
6.133LeuPro: 6.133 ± 0.0
2.582LeuGln: 2.582 ± 0.0
4.196LeuArg: 4.196 ± 0.0
7.747LeuSer: 7.747 ± 0.0
4.519LeuThr: 4.519 ± 0.0
5.487LeuVal: 5.487 ± 0.0
0.968LeuTrp: 0.968 ± 0.0
2.582LeuTyr: 2.582 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.968MetAla: 0.968 ± 0.0
0.323MetCys: 0.323 ± 0.0
0.323MetAsp: 0.323 ± 0.0
0.968MetGlu: 0.968 ± 0.0
1.937MetPhe: 1.937 ± 0.0
0.968MetGly: 0.968 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.968MetIle: 0.968 ± 0.0
0.968MetLys: 0.968 ± 0.0
3.873MetLeu: 3.873 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.291MetAsn: 1.291 ± 0.0
2.26MetPro: 2.26 ± 0.0
1.614MetGln: 1.614 ± 0.0
1.937MetArg: 1.937 ± 0.0
1.937MetSer: 1.937 ± 0.0
1.291MetThr: 1.291 ± 0.0
2.26MetVal: 2.26 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.291MetTyr: 1.291 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.228AsnAla: 3.228 ± 0.0
0.646AsnCys: 0.646 ± 0.0
1.291AsnAsp: 1.291 ± 0.0
0.646AsnGlu: 0.646 ± 0.0
0.968AsnPhe: 0.968 ± 0.0
2.905AsnGly: 2.905 ± 0.0
0.968AsnHis: 0.968 ± 0.0
0.646AsnIle: 0.646 ± 0.0
1.291AsnLys: 1.291 ± 0.0
2.26AsnLeu: 2.26 ± 0.0
1.291AsnMet: 1.291 ± 0.0
0.968AsnAsn: 0.968 ± 0.0
3.228AsnPro: 3.228 ± 0.0
0.323AsnGln: 0.323 ± 0.0
1.291AsnArg: 1.291 ± 0.0
2.582AsnSer: 2.582 ± 0.0
1.614AsnThr: 1.614 ± 0.0
4.842AsnVal: 4.842 ± 0.0
0.646AsnTrp: 0.646 ± 0.0
0.646AsnTyr: 0.646 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.873ProAla: 3.873 ± 0.0
0.646ProCys: 0.646 ± 0.0
1.291ProAsp: 1.291 ± 0.0
4.196ProGlu: 4.196 ± 0.0
3.228ProPhe: 3.228 ± 0.0
2.26ProGly: 2.26 ± 0.0
2.582ProHis: 2.582 ± 0.0
5.165ProIle: 5.165 ± 0.0
3.228ProLys: 3.228 ± 0.0
5.487ProLeu: 5.487 ± 0.0
2.26ProMet: 2.26 ± 0.0
2.26ProAsn: 2.26 ± 0.0
3.873ProPro: 3.873 ± 0.0
2.26ProGln: 2.26 ± 0.0
1.614ProArg: 1.614 ± 0.0
9.361ProSer: 9.361 ± 0.0
6.133ProThr: 6.133 ± 0.0
6.133ProVal: 6.133 ± 0.0
1.291ProTrp: 1.291 ± 0.0
2.26ProTyr: 2.26 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.968GlnAla: 0.968 ± 0.0
0.646GlnCys: 0.646 ± 0.0
0.968GlnAsp: 0.968 ± 0.0
2.905GlnGlu: 2.905 ± 0.0
1.614GlnPhe: 1.614 ± 0.0
2.26GlnGly: 2.26 ± 0.0
0.646GlnHis: 0.646 ± 0.0
1.937GlnIle: 1.937 ± 0.0
1.291GlnLys: 1.291 ± 0.0
2.26GlnLeu: 2.26 ± 0.0
0.323GlnMet: 0.323 ± 0.0
0.646GlnAsn: 0.646 ± 0.0
2.26GlnPro: 2.26 ± 0.0
1.937GlnGln: 1.937 ± 0.0
0.968GlnArg: 0.968 ± 0.0
3.228GlnSer: 3.228 ± 0.0
2.582GlnThr: 2.582 ± 0.0
2.905GlnVal: 2.905 ± 0.0
0.646GlnTrp: 0.646 ± 0.0
0.646GlnTyr: 0.646 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.582ArgAla: 2.582 ± 0.0
0.323ArgCys: 0.323 ± 0.0
2.26ArgAsp: 2.26 ± 0.0
1.937ArgGlu: 1.937 ± 0.0
1.937ArgPhe: 1.937 ± 0.0
2.582ArgGly: 2.582 ± 0.0
1.291ArgHis: 1.291 ± 0.0
2.582ArgIle: 2.582 ± 0.0
2.905ArgLys: 2.905 ± 0.0
5.487ArgLeu: 5.487 ± 0.0
1.614ArgMet: 1.614 ± 0.0
3.228ArgAsn: 3.228 ± 0.0
2.905ArgPro: 2.905 ± 0.0
2.26ArgGln: 2.26 ± 0.0
1.937ArgArg: 1.937 ± 0.0
2.582ArgSer: 2.582 ± 0.0
2.26ArgThr: 2.26 ± 0.0
5.165ArgVal: 5.165 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
0.646ArgTyr: 0.646 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
7.747SerAla: 7.747 ± 0.0
1.614SerCys: 1.614 ± 0.0
3.551SerAsp: 3.551 ± 0.0
3.228SerGlu: 3.228 ± 0.0
4.196SerPhe: 4.196 ± 0.0
5.487SerGly: 5.487 ± 0.0
0.968SerHis: 0.968 ± 0.0
4.196SerIle: 4.196 ± 0.0
3.873SerLys: 3.873 ± 0.0
10.329SerLeu: 10.329 ± 0.0
3.551SerMet: 3.551 ± 0.0
1.614SerAsn: 1.614 ± 0.0
4.842SerPro: 4.842 ± 0.0
4.519SerGln: 4.519 ± 0.0
4.196SerArg: 4.196 ± 0.0
13.234SerSer: 13.234 ± 0.0
7.747SerThr: 7.747 ± 0.0
7.424SerVal: 7.424 ± 0.0
1.291SerTrp: 1.291 ± 0.0
3.228SerTyr: 3.228 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.81ThrAla: 5.81 ± 0.0
0.323ThrCys: 0.323 ± 0.0
1.614ThrAsp: 1.614 ± 0.0
2.905ThrGlu: 2.905 ± 0.0
2.582ThrPhe: 2.582 ± 0.0
4.842ThrGly: 4.842 ± 0.0
0.646ThrHis: 0.646 ± 0.0
5.81ThrIle: 5.81 ± 0.0
1.614ThrLys: 1.614 ± 0.0
5.487ThrLeu: 5.487 ± 0.0
1.291ThrMet: 1.291 ± 0.0
2.582ThrAsn: 2.582 ± 0.0
5.81ThrPro: 5.81 ± 0.0
1.937ThrGln: 1.937 ± 0.0
2.905ThrArg: 2.905 ± 0.0
6.779ThrSer: 6.779 ± 0.0
3.228ThrThr: 3.228 ± 0.0
3.551ThrVal: 3.551 ± 0.0
0.968ThrTrp: 0.968 ± 0.0
0.968ThrTyr: 0.968 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.487ValAla: 5.487 ± 0.0
1.614ValCys: 1.614 ± 0.0
2.905ValAsp: 2.905 ± 0.0
4.196ValGlu: 4.196 ± 0.0
3.551ValPhe: 3.551 ± 0.0
4.196ValGly: 4.196 ± 0.0
1.291ValHis: 1.291 ± 0.0
3.551ValIle: 3.551 ± 0.0
2.582ValLys: 2.582 ± 0.0
8.07ValLeu: 8.07 ± 0.0
1.614ValMet: 1.614 ± 0.0
1.937ValAsn: 1.937 ± 0.0
9.684ValPro: 9.684 ± 0.0
2.582ValGln: 2.582 ± 0.0
3.873ValArg: 3.873 ± 0.0
4.519ValSer: 4.519 ± 0.0
4.196ValThr: 4.196 ± 0.0
6.133ValVal: 6.133 ± 0.0
0.968ValTrp: 0.968 ± 0.0
2.905ValTyr: 2.905 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.291TrpAla: 1.291 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.323TrpAsp: 0.323 ± 0.0
0.968TrpGlu: 0.968 ± 0.0
0.646TrpPhe: 0.646 ± 0.0
0.968TrpGly: 0.968 ± 0.0
0.323TrpHis: 0.323 ± 0.0
0.968TrpIle: 0.968 ± 0.0
0.968TrpLys: 0.968 ± 0.0
1.614TrpLeu: 1.614 ± 0.0
0.323TrpMet: 0.323 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.323TrpPro: 0.323 ± 0.0
0.323TrpGln: 0.323 ± 0.0
1.291TrpArg: 1.291 ± 0.0
2.26TrpSer: 2.26 ± 0.0
1.614TrpThr: 1.614 ± 0.0
1.937TrpVal: 1.937 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.323TrpTyr: 0.323 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.26TyrAla: 2.26 ± 0.0
0.968TyrCys: 0.968 ± 0.0
2.26TyrAsp: 2.26 ± 0.0
0.968TyrGlu: 0.968 ± 0.0
1.614TyrPhe: 1.614 ± 0.0
2.26TyrGly: 2.26 ± 0.0
0.646TyrHis: 0.646 ± 0.0
1.291TyrIle: 1.291 ± 0.0
1.291TyrLys: 1.291 ± 0.0
3.873TyrLeu: 3.873 ± 0.0
0.646TyrMet: 0.646 ± 0.0
0.968TyrAsn: 0.968 ± 0.0
1.291TyrPro: 1.291 ± 0.0
0.323TyrGln: 0.323 ± 0.0
1.937TyrArg: 1.937 ± 0.0
3.228TyrSer: 3.228 ± 0.0
2.26TyrThr: 2.26 ± 0.0
2.582TyrVal: 2.582 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.968TyrTyr: 0.968 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3099 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski