Amino acid dipepetide frequency for Cryphonectria hypovirus 1 (strain Euro7) (CHV-1/Euro7) (Chestnut blight fungus hypovirulence-associated virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.605AlaAla: 6.605 ± 4.774
1.057AlaCys: 1.057 ± 0.278
4.227AlaAsp: 4.227 ± 1.318
6.605AlaGlu: 6.605 ± 0.725
2.642AlaPhe: 2.642 ± 0.29
5.284AlaGly: 5.284 ± 1.04
0.793AlaHis: 0.793 ± 0.399
3.435AlaIle: 3.435 ± 1.511
4.756AlaLys: 4.756 ± 2.466
6.341AlaLeu: 6.341 ± 0.858
2.378AlaMet: 2.378 ± 1.197
1.849AlaAsn: 1.849 ± 0.931
1.321AlaPro: 1.321 ± 0.665
2.378AlaGln: 2.378 ± 0.423
7.662AlaArg: 7.662 ± 5.052
3.435AlaSer: 3.435 ± 0.701
4.756AlaThr: 4.756 ± 0.036
5.284AlaVal: 5.284 ± 0.58
1.585AlaTrp: 1.585 ± 0.798
1.849AlaTyr: 1.849 ± 0.121
0.0AlaXaa: 0.0 ± 0.0
Cys
0.528CysAla: 0.528 ± 0.544
0.0CysCys: 0.0 ± 0.0
0.528CysAsp: 0.528 ± 0.266
0.528CysGlu: 0.528 ± 0.266
0.528CysPhe: 0.528 ± 0.266
1.057CysGly: 1.057 ± 0.278
0.264CysHis: 0.264 ± 0.133
0.528CysIle: 0.528 ± 0.544
1.321CysLys: 1.321 ± 0.145
1.321CysLeu: 1.321 ± 0.145
0.528CysMet: 0.528 ± 0.544
0.528CysAsn: 0.528 ± 0.266
0.264CysPro: 0.264 ± 0.677
0.264CysGln: 0.264 ± 0.677
1.321CysArg: 1.321 ± 0.145
1.321CysSer: 1.321 ± 0.955
1.321CysThr: 1.321 ± 0.145
0.793CysVal: 0.793 ± 0.411
0.0CysTrp: 0.0 ± 0.0
0.793CysTyr: 0.793 ± 0.411
0.0CysXaa: 0.0 ± 0.0
Asp
3.435AspAla: 3.435 ± 1.511
0.0AspCys: 0.0 ± 0.0
1.057AspAsp: 1.057 ± 0.532
3.17AspGlu: 3.17 ± 1.596
2.642AspPhe: 2.642 ± 0.29
5.02AspGly: 5.02 ± 1.523
1.321AspHis: 1.321 ± 0.145
2.642AspIle: 2.642 ± 1.33
2.114AspLys: 2.114 ± 0.254
3.963AspLeu: 3.963 ± 0.375
1.321AspMet: 1.321 ± 0.665
2.906AspAsn: 2.906 ± 1.463
5.02AspPro: 5.02 ± 2.333
1.321AspGln: 1.321 ± 0.665
4.491AspArg: 4.491 ± 1.451
4.227AspSer: 4.227 ± 0.302
2.642AspThr: 2.642 ± 0.29
4.227AspVal: 4.227 ± 0.302
0.793AspTrp: 0.793 ± 0.399
3.17AspTyr: 3.17 ± 0.024
0.0AspXaa: 0.0 ± 0.0
Glu
4.491GluAla: 4.491 ± 0.169
0.528GluCys: 0.528 ± 0.544
2.906GluAsp: 2.906 ± 1.463
5.812GluGlu: 5.812 ± 0.496
2.378GluPhe: 2.378 ± 1.233
2.114GluGly: 2.114 ± 0.254
2.114GluHis: 2.114 ± 1.366
3.17GluIle: 3.17 ± 0.786
1.849GluLys: 1.849 ± 0.931
6.341GluLeu: 6.341 ± 0.762
1.321GluMet: 1.321 ± 0.665
2.378GluAsn: 2.378 ± 1.197
3.963GluPro: 3.963 ± 1.185
2.906GluGln: 2.906 ± 0.157
2.378GluArg: 2.378 ± 0.387
1.321GluSer: 1.321 ± 0.955
2.642GluThr: 2.642 ± 0.52
5.548GluVal: 5.548 ± 0.363
1.321GluTrp: 1.321 ± 0.665
1.585GluTyr: 1.585 ± 0.012
0.0GluXaa: 0.0 ± 0.0
Phe
5.02PheAla: 5.02 ± 0.907
0.793PheCys: 0.793 ± 0.411
2.378PheAsp: 2.378 ± 0.387
2.642PheGlu: 2.642 ± 0.52
2.378PhePhe: 2.378 ± 1.197
3.699PheGly: 3.699 ± 1.378
2.114PheHis: 2.114 ± 1.064
2.642PheIle: 2.642 ± 1.33
1.849PheLys: 1.849 ± 0.931
4.227PheLeu: 4.227 ± 1.318
1.849PheMet: 1.849 ± 0.231
0.793PheAsn: 0.793 ± 0.399
1.585PhePro: 1.585 ± 0.012
1.057PheGln: 1.057 ± 0.278
3.699PheArg: 3.699 ± 1.378
1.057PheSer: 1.057 ± 0.532
1.585PheThr: 1.585 ± 0.798
3.963PheVal: 3.963 ± 0.375
1.321PheTrp: 1.321 ± 0.665
1.849PheTyr: 1.849 ± 0.121
0.0PheXaa: 0.0 ± 0.0
Gly
2.642GlyAla: 2.642 ± 0.52
1.849GlyCys: 1.849 ± 0.121
3.435GlyAsp: 3.435 ± 0.701
1.585GlyGlu: 1.585 ± 0.798
3.17GlyPhe: 3.17 ± 0.786
3.435GlyGly: 3.435 ± 1.729
1.321GlyHis: 1.321 ± 0.665
3.699GlyIle: 3.699 ± 1.862
5.812GlyLys: 5.812 ± 2.116
7.133GlyLeu: 7.133 ± 0.459
2.378GlyMet: 2.378 ± 0.501
1.321GlyAsn: 1.321 ± 0.955
1.321GlyPro: 1.321 ± 0.145
2.642GlyGln: 2.642 ± 0.29
6.077GlyArg: 6.077 ± 1.801
3.699GlySer: 3.699 ± 0.568
2.114GlyThr: 2.114 ± 0.556
3.699GlyVal: 3.699 ± 1.052
1.321GlyTrp: 1.321 ± 0.955
1.849GlyTyr: 1.849 ± 0.689
0.0GlyXaa: 0.0 ± 0.0
His
1.585HisAla: 1.585 ± 0.798
0.264HisCys: 0.264 ± 0.133
0.793HisAsp: 0.793 ± 0.399
1.849HisGlu: 1.849 ± 0.121
1.057HisPhe: 1.057 ± 0.278
2.114HisGly: 2.114 ± 0.556
1.321HisHis: 1.321 ± 0.665
1.585HisIle: 1.585 ± 0.798
1.321HisLys: 1.321 ± 0.955
3.435HisLeu: 3.435 ± 0.919
0.793HisMet: 0.793 ± 1.221
1.057HisAsn: 1.057 ± 0.532
1.321HisPro: 1.321 ± 0.145
1.321HisGln: 1.321 ± 0.145
0.528HisArg: 0.528 ± 0.266
0.793HisSer: 0.793 ± 0.411
1.321HisThr: 1.321 ± 0.145
2.378HisVal: 2.378 ± 1.233
1.057HisTrp: 1.057 ± 0.532
1.057HisTyr: 1.057 ± 0.532
0.0HisXaa: 0.0 ± 0.0
Ile
3.435IleAla: 3.435 ± 0.919
1.057IleCys: 1.057 ± 0.278
2.114IleAsp: 2.114 ± 1.064
3.435IleGlu: 3.435 ± 0.109
2.114IlePhe: 2.114 ± 0.254
3.699IleGly: 3.699 ± 0.242
1.585IleHis: 1.585 ± 0.012
2.378IleIle: 2.378 ± 0.387
2.642IleLys: 2.642 ± 1.33
4.227IleLeu: 4.227 ± 2.128
1.321IleMet: 1.321 ± 0.665
1.585IleAsn: 1.585 ± 0.798
3.435IlePro: 3.435 ± 1.729
1.849IleGln: 1.849 ± 1.499
4.227IleArg: 4.227 ± 0.508
2.906IleSer: 2.906 ± 0.157
2.378IleThr: 2.378 ± 0.387
2.906IleVal: 2.906 ± 1.777
1.321IleTrp: 1.321 ± 0.955
1.585IleTyr: 1.585 ± 0.798
0.0IleXaa: 0.0 ± 0.0
Lys
4.491LysAla: 4.491 ± 0.979
0.264LysCys: 0.264 ± 0.677
3.17LysAsp: 3.17 ± 1.596
4.227LysGlu: 4.227 ± 1.318
2.642LysPhe: 2.642 ± 0.52
3.435LysGly: 3.435 ± 0.919
0.528LysHis: 0.528 ± 0.266
2.642LysIle: 2.642 ± 1.1
2.906LysLys: 2.906 ± 0.967
6.605LysLeu: 6.605 ± 0.895
0.264LysMet: 0.264 ± 0.133
1.057LysAsn: 1.057 ± 0.532
2.906LysPro: 2.906 ± 0.967
1.321LysGln: 1.321 ± 0.145
3.963LysArg: 3.963 ± 0.435
3.435LysSer: 3.435 ± 0.109
2.642LysThr: 2.642 ± 1.33
1.849LysVal: 1.849 ± 0.121
0.793LysTrp: 0.793 ± 0.399
2.114LysTyr: 2.114 ± 1.064
0.0LysXaa: 0.0 ± 0.0
Leu
7.398LeuAla: 7.398 ± 3.565
1.321LeuCys: 1.321 ± 0.145
4.227LeuAsp: 4.227 ± 0.302
4.227LeuGlu: 4.227 ± 1.318
4.227LeuPhe: 4.227 ± 1.318
2.642LeuGly: 2.642 ± 1.33
2.378LeuHis: 2.378 ± 0.387
3.699LeuIle: 3.699 ± 1.052
5.812LeuLys: 5.812 ± 1.306
8.719LeuLeu: 8.719 ± 1.959
1.585LeuMet: 1.585 ± 0.798
2.114LeuAsn: 2.114 ± 0.556
7.662LeuPro: 7.662 ± 2.237
2.906LeuGln: 2.906 ± 0.157
7.926LeuArg: 7.926 ± 4.109
5.548LeuSer: 5.548 ± 0.363
3.963LeuThr: 3.963 ± 0.375
7.133LeuVal: 7.133 ± 1.161
2.114LeuTrp: 2.114 ± 0.556
2.378LeuTyr: 2.378 ± 1.197
0.0LeuXaa: 0.0 ± 0.0
Met
3.17MetAla: 3.17 ± 0.024
0.0MetCys: 0.0 ± 0.0
1.585MetAsp: 1.585 ± 0.798
0.793MetGlu: 0.793 ± 0.399
0.793MetPhe: 0.793 ± 0.399
0.793MetGly: 0.793 ± 0.411
0.264MetHis: 0.264 ± 0.133
1.321MetIle: 1.321 ± 0.145
0.793MetLys: 0.793 ± 0.399
2.114MetLeu: 2.114 ± 1.064
0.264MetMet: 0.264 ± 0.133
0.528MetAsn: 0.528 ± 0.266
2.906MetPro: 2.906 ± 0.157
1.057MetGln: 1.057 ± 0.532
0.793MetArg: 0.793 ± 0.399
1.057MetSer: 1.057 ± 1.088
1.321MetThr: 1.321 ± 0.955
1.321MetVal: 1.321 ± 0.145
1.585MetTrp: 1.585 ± 0.798
1.585MetTyr: 1.585 ± 0.798
0.0MetXaa: 0.0 ± 0.0
Asn
1.057AsnAla: 1.057 ± 0.532
0.528AsnCys: 0.528 ± 0.266
1.849AsnAsp: 1.849 ± 0.121
1.849AsnGlu: 1.849 ± 0.931
1.321AsnPhe: 1.321 ± 0.145
1.849AsnGly: 1.849 ± 0.121
1.585AsnHis: 1.585 ± 0.798
1.585AsnIle: 1.585 ± 0.012
0.793AsnLys: 0.793 ± 0.411
3.699AsnLeu: 3.699 ± 1.052
0.793AsnMet: 0.793 ± 0.399
0.528AsnAsn: 0.528 ± 0.266
3.17AsnPro: 3.17 ± 0.786
1.585AsnGln: 1.585 ± 0.822
3.435AsnArg: 3.435 ± 1.729
0.793AsnSer: 0.793 ± 0.399
1.849AsnThr: 1.849 ± 0.931
3.17AsnVal: 3.17 ± 1.644
1.321AsnTrp: 1.321 ± 0.665
1.321AsnTyr: 1.321 ± 0.665
0.0AsnXaa: 0.0 ± 0.0
Pro
2.906ProAla: 2.906 ± 0.653
0.793ProCys: 0.793 ± 0.399
3.17ProAsp: 3.17 ± 0.786
2.906ProGlu: 2.906 ± 0.653
3.699ProPhe: 3.699 ± 1.052
5.02ProGly: 5.02 ± 0.097
1.057ProHis: 1.057 ± 0.532
2.642ProIle: 2.642 ± 1.33
2.114ProLys: 2.114 ± 1.064
4.227ProLeu: 4.227 ± 0.302
1.057ProMet: 1.057 ± 0.278
1.585ProAsn: 1.585 ± 0.798
3.435ProPro: 3.435 ± 0.919
2.114ProGln: 2.114 ± 0.556
6.605ProArg: 6.605 ± 0.895
4.756ProSer: 4.756 ± 0.846
5.284ProThr: 5.284 ± 0.58
5.284ProVal: 5.284 ± 1.39
0.528ProTrp: 0.528 ± 0.266
2.378ProTyr: 2.378 ± 0.387
0.0ProXaa: 0.0 ± 0.0
Gln
3.435GlnAla: 3.435 ± 0.109
0.528GlnCys: 0.528 ± 0.544
2.114GlnAsp: 2.114 ± 1.366
1.585GlnGlu: 1.585 ± 0.822
2.642GlnPhe: 2.642 ± 0.52
3.435GlnGly: 3.435 ± 0.109
0.264GlnHis: 0.264 ± 0.133
1.849GlnIle: 1.849 ± 0.689
1.849GlnLys: 1.849 ± 0.121
2.378GlnLeu: 2.378 ± 0.423
0.264GlnMet: 0.264 ± 0.133
1.585GlnAsn: 1.585 ± 0.798
2.378GlnPro: 2.378 ± 1.197
0.528GlnGln: 0.528 ± 0.266
1.849GlnArg: 1.849 ± 0.689
2.642GlnSer: 2.642 ± 0.29
1.321GlnThr: 1.321 ± 0.145
1.849GlnVal: 1.849 ± 0.121
1.057GlnTrp: 1.057 ± 0.278
0.793GlnTyr: 0.793 ± 0.399
0.0GlnXaa: 0.0 ± 0.0
Arg
3.963ArgAla: 3.963 ± 1.245
0.793ArgCys: 0.793 ± 0.411
6.605ArgAsp: 6.605 ± 3.964
2.114ArgGlu: 2.114 ± 0.254
5.02ArgPhe: 5.02 ± 0.097
2.906ArgGly: 2.906 ± 0.157
2.114ArgHis: 2.114 ± 2.176
3.699ArgIle: 3.699 ± 1.052
3.435ArgLys: 3.435 ± 1.511
7.133ArgLeu: 7.133 ± 1.269
1.057ArgMet: 1.057 ± 0.278
3.699ArgAsn: 3.699 ± 0.568
4.491ArgPro: 4.491 ± 0.979
2.906ArgGln: 2.906 ± 0.653
5.812ArgArg: 5.812 ± 7.603
8.454ArgSer: 8.454 ± 2.224
3.17ArgThr: 3.17 ± 2.454
3.699ArgVal: 3.699 ± 0.568
0.793ArgTrp: 0.793 ± 0.411
5.02ArgTyr: 5.02 ± 1.717
0.0ArgXaa: 0.0 ± 0.0
Ser
5.548SerAla: 5.548 ± 1.257
0.793SerCys: 0.793 ± 1.221
3.435SerAsp: 3.435 ± 0.701
3.699SerGlu: 3.699 ± 1.378
2.114SerPhe: 2.114 ± 0.556
3.963SerGly: 3.963 ± 1.185
1.585SerHis: 1.585 ± 0.822
4.491SerIle: 4.491 ± 0.169
2.642SerLys: 2.642 ± 1.33
3.699SerLeu: 3.699 ± 2.188
1.321SerMet: 1.321 ± 0.665
2.906SerAsn: 2.906 ± 0.157
2.114SerPro: 2.114 ± 0.254
2.642SerGln: 2.642 ± 0.52
2.906SerArg: 2.906 ± 0.967
5.02SerSer: 5.02 ± 0.097
3.17SerThr: 3.17 ± 0.834
4.227SerVal: 4.227 ± 2.732
2.114SerTrp: 2.114 ± 0.556
2.378SerTyr: 2.378 ± 0.387
0.0SerXaa: 0.0 ± 0.0
Thr
5.02ThrAla: 5.02 ± 2.527
0.264ThrCys: 0.264 ± 0.133
1.849ThrAsp: 1.849 ± 0.931
3.435ThrGlu: 3.435 ± 0.701
2.642ThrPhe: 2.642 ± 1.33
3.699ThrGly: 3.699 ± 0.568
1.321ThrHis: 1.321 ± 0.665
1.585ThrIle: 1.585 ± 0.798
2.906ThrLys: 2.906 ± 1.777
2.114ThrLeu: 2.114 ± 0.556
1.585ThrMet: 1.585 ± 0.012
2.114ThrAsn: 2.114 ± 0.254
3.963ThrPro: 3.963 ± 0.435
1.057ThrGln: 1.057 ± 0.532
3.699ThrArg: 3.699 ± 1.378
3.17ThrSer: 3.17 ± 1.644
3.435ThrThr: 3.435 ± 2.321
5.02ThrVal: 5.02 ± 1.523
2.114ThrTrp: 2.114 ± 0.254
1.585ThrTyr: 1.585 ± 0.798
0.0ThrXaa: 0.0 ± 0.0
Val
5.02ValAla: 5.02 ± 4.762
1.585ValCys: 1.585 ± 0.012
6.077ValAsp: 6.077 ± 1.801
3.963ValGlu: 3.963 ± 0.375
3.17ValPhe: 3.17 ± 1.596
2.114ValGly: 2.114 ± 1.366
2.642ValHis: 2.642 ± 1.1
4.491ValIle: 4.491 ± 0.169
2.642ValLys: 2.642 ± 0.52
5.02ValLeu: 5.02 ± 0.097
1.849ValMet: 1.849 ± 0.931
2.378ValAsn: 2.378 ± 0.423
6.341ValPro: 6.341 ± 0.762
1.585ValGln: 1.585 ± 0.012
5.02ValArg: 5.02 ± 3.143
4.491ValSer: 4.491 ± 0.979
4.491ValThr: 4.491 ± 0.169
3.699ValVal: 3.699 ± 1.378
1.585ValTrp: 1.585 ± 0.798
2.378ValTyr: 2.378 ± 0.387
0.0ValXaa: 0.0 ± 0.0
Trp
2.114TrpAla: 2.114 ± 0.254
1.057TrpCys: 1.057 ± 0.278
1.057TrpAsp: 1.057 ± 0.532
1.321TrpGlu: 1.321 ± 0.145
0.264TrpPhe: 0.264 ± 0.133
1.321TrpGly: 1.321 ± 0.145
0.793TrpHis: 0.793 ± 0.399
0.793TrpIle: 0.793 ± 0.411
1.321TrpLys: 1.321 ± 0.665
1.849TrpLeu: 1.849 ± 0.931
0.528TrpMet: 0.528 ± 0.266
1.057TrpAsn: 1.057 ± 0.278
1.321TrpPro: 1.321 ± 0.665
1.321TrpGln: 1.321 ± 0.665
2.378TrpArg: 2.378 ± 1.233
1.057TrpSer: 1.057 ± 0.278
0.793TrpThr: 0.793 ± 0.399
2.114TrpVal: 2.114 ± 0.254
1.321TrpTrp: 1.321 ± 0.665
0.793TrpTyr: 0.793 ± 0.399
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.378TyrAla: 2.378 ± 0.387
0.264TyrCys: 0.264 ± 0.677
2.906TyrAsp: 2.906 ± 0.653
1.321TyrGlu: 1.321 ± 0.145
1.321TyrPhe: 1.321 ± 0.145
2.906TyrGly: 2.906 ± 1.463
1.585TyrHis: 1.585 ± 0.012
1.321TyrIle: 1.321 ± 0.665
2.378TyrLys: 2.378 ± 1.197
3.435TyrLeu: 3.435 ± 0.109
1.321TyrMet: 1.321 ± 0.145
2.114TyrAsn: 2.114 ± 1.064
2.642TyrPro: 2.642 ± 1.33
1.585TyrGln: 1.585 ± 0.012
2.114TyrArg: 2.114 ± 0.254
1.585TyrSer: 1.585 ± 0.798
2.378TyrThr: 2.378 ± 1.197
2.378TyrVal: 2.378 ± 0.387
0.528TyrTrp: 0.528 ± 0.266
0.264TyrTyr: 0.264 ± 0.133
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3786 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski