Amino acid dipepetide frequency for Hubei permutotetra-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.567AlaAla: 5.567 ± 1.824
0.696AlaCys: 0.696 ± 1.337
1.392AlaAsp: 1.392 ± 0.745
2.088AlaGlu: 2.088 ± 1.005
0.696AlaPhe: 0.696 ± 0.373
4.175AlaGly: 4.175 ± 0.494
1.392AlaHis: 1.392 ± 1.111
6.263AlaIle: 6.263 ± 2.935
8.351AlaLys: 8.351 ± 2.681
6.959AlaLeu: 6.959 ± 1.044
2.784AlaMet: 2.784 ± 0.979
2.088AlaAsn: 2.088 ± 1.005
5.567AlaPro: 5.567 ± 3.228
2.784AlaGln: 2.784 ± 1.491
4.175AlaArg: 4.175 ± 2.236
4.175AlaSer: 4.175 ± 2.01
7.655AlaThr: 7.655 ± 2.281
6.959AlaVal: 6.959 ± 2.226
1.392AlaTrp: 1.392 ± 0.745
3.479AlaTyr: 3.479 ± 1.051
0.0AlaXaa: 0.0 ± 0.0
Cys
0.696CysAla: 0.696 ± 1.337
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.696CysGlu: 0.696 ± 1.424
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.696CysIle: 0.696 ± 1.424
2.088CysLys: 2.088 ± 1.612
1.392CysLeu: 1.392 ± 0.745
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.696CysPro: 0.696 ± 0.373
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.696CysSer: 0.696 ± 0.373
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.263AspAla: 6.263 ± 0.625
0.0AspCys: 0.0 ± 0.0
2.784AspAsp: 2.784 ± 0.979
4.871AspGlu: 4.871 ± 1.52
3.479AspPhe: 3.479 ± 2.06
6.263AspGly: 6.263 ± 2.266
0.696AspHis: 0.696 ± 0.373
0.696AspIle: 0.696 ± 0.373
3.479AspLys: 3.479 ± 0.866
7.655AspLeu: 7.655 ± 4.001
1.392AspMet: 1.392 ± 0.745
0.0AspAsn: 0.0 ± 0.0
3.479AspPro: 3.479 ± 1.864
0.696AspGln: 0.696 ± 0.373
3.479AspArg: 3.479 ± 1.864
1.392AspSer: 1.392 ± 2.848
5.567AspThr: 5.567 ± 2.478
6.263AspVal: 6.263 ± 2.063
0.696AspTrp: 0.696 ± 0.373
2.088AspTyr: 2.088 ± 3.07
0.0AspXaa: 0.0 ± 0.0
Glu
6.263GluAla: 6.263 ± 2.151
0.0GluCys: 0.0 ± 0.0
2.088GluAsp: 2.088 ± 1.118
6.959GluGlu: 6.959 ± 3.727
0.696GluPhe: 0.696 ± 1.337
4.175GluGly: 4.175 ± 2.236
0.696GluHis: 0.696 ± 0.373
2.784GluIle: 2.784 ± 0.958
4.871GluLys: 4.871 ± 2.609
7.655GluLeu: 7.655 ± 4.1
0.696GluMet: 0.696 ± 1.424
0.696GluAsn: 0.696 ± 0.373
2.088GluPro: 2.088 ± 1.612
4.175GluGln: 4.175 ± 2.236
1.392GluArg: 1.392 ± 1.175
1.392GluSer: 1.392 ± 0.745
4.871GluThr: 4.871 ± 1.52
2.088GluVal: 2.088 ± 1.005
2.088GluTrp: 2.088 ± 0.978
1.392GluTyr: 1.392 ± 0.745
0.0GluXaa: 0.0 ± 0.0
Phe
2.088PheAla: 2.088 ± 0.978
0.696PheCys: 0.696 ± 0.373
3.479PheAsp: 3.479 ± 2.06
1.392PheGlu: 1.392 ± 0.745
0.696PhePhe: 0.696 ± 1.424
2.088PheGly: 2.088 ± 0.978
0.0PheHis: 0.0 ± 0.0
2.784PheIle: 2.784 ± 0.979
4.175PheLys: 4.175 ± 2.236
2.088PheLeu: 2.088 ± 1.118
2.784PheMet: 2.784 ± 1.491
2.088PheAsn: 2.088 ± 1.612
2.088PhePro: 2.088 ± 2.429
0.0PheGln: 0.0 ± 0.0
0.696PheArg: 0.696 ± 0.373
5.567PheSer: 5.567 ± 1.427
2.784PheThr: 2.784 ± 2.719
2.088PheVal: 2.088 ± 3.07
0.696PheTrp: 0.696 ± 0.373
0.696PheTyr: 0.696 ± 1.337
0.0PheXaa: 0.0 ± 0.0
Gly
6.959GlyAla: 6.959 ± 2.663
0.0GlyCys: 0.0 ± 0.0
2.784GlyAsp: 2.784 ± 0.979
3.479GlyGlu: 3.479 ± 1.864
2.088GlyPhe: 2.088 ± 0.978
2.088GlyGly: 2.088 ± 0.978
0.0GlyHis: 0.0 ± 0.0
3.479GlyIle: 3.479 ± 1.051
6.959GlyLys: 6.959 ± 1.044
4.871GlyLeu: 4.871 ± 1.52
0.696GlyMet: 0.696 ± 0.373
2.088GlyAsn: 2.088 ± 1.005
1.392GlyPro: 1.392 ± 1.175
2.088GlyGln: 2.088 ± 0.978
2.088GlyArg: 2.088 ± 1.118
2.784GlySer: 2.784 ± 2.221
5.567GlyThr: 5.567 ± 2.982
2.088GlyVal: 2.088 ± 1.118
2.088GlyTrp: 2.088 ± 0.978
0.696GlyTyr: 0.696 ± 0.373
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.696HisAsp: 0.696 ± 0.373
0.696HisGlu: 0.696 ± 0.373
2.088HisPhe: 2.088 ± 0.978
2.784HisGly: 2.784 ± 1.491
0.0HisHis: 0.0 ± 0.0
0.696HisIle: 0.696 ± 0.373
0.0HisLys: 0.0 ± 0.0
0.696HisLeu: 0.696 ± 0.373
0.696HisMet: 0.696 ± 0.323
0.696HisAsn: 0.696 ± 0.373
2.088HisPro: 2.088 ± 1.118
0.0HisGln: 0.0 ± 0.0
1.392HisArg: 1.392 ± 1.111
0.0HisSer: 0.0 ± 0.0
1.392HisThr: 1.392 ± 1.111
0.0HisVal: 0.0 ± 0.0
2.088HisTrp: 2.088 ± 0.978
0.696HisTyr: 0.696 ± 1.424
0.0HisXaa: 0.0 ± 0.0
Ile
4.175IleAla: 4.175 ± 1.34
0.0IleCys: 0.0 ± 0.0
4.871IleAsp: 4.871 ± 0.121
0.696IleGlu: 0.696 ± 0.373
1.392IlePhe: 1.392 ± 1.111
0.696IleGly: 0.696 ± 0.373
0.696IleHis: 0.696 ± 0.373
2.784IleIle: 2.784 ± 2.221
6.263IleLys: 6.263 ± 5.314
3.479IleLeu: 3.479 ± 2.154
2.088IleMet: 2.088 ± 1.118
2.784IleAsn: 2.784 ± 1.491
0.696IlePro: 0.696 ± 0.373
0.0IleGln: 0.0 ± 0.0
1.392IleArg: 1.392 ± 0.745
3.479IleSer: 3.479 ± 1.113
3.479IleThr: 3.479 ± 0.866
1.392IleVal: 1.392 ± 0.745
0.0IleTrp: 0.0 ± 0.0
2.088IleTyr: 2.088 ± 1.005
0.0IleXaa: 0.0 ± 0.0
Lys
4.175LysAla: 4.175 ± 1.252
0.0LysCys: 0.0 ± 0.0
6.959LysAsp: 6.959 ± 2.609
4.175LysGlu: 4.175 ± 1.252
4.175LysPhe: 4.175 ± 2.236
3.479LysGly: 3.479 ± 1.113
1.392LysHis: 1.392 ± 0.745
2.088LysIle: 2.088 ± 1.005
7.655LysLys: 7.655 ± 2.281
4.871LysLeu: 4.871 ± 1.52
1.392LysMet: 1.392 ± 1.985
5.567LysAsn: 5.567 ± 0.252
6.263LysPro: 6.263 ± 3.543
4.871LysGln: 4.871 ± 1.928
3.479LysArg: 3.479 ± 0.866
6.959LysSer: 6.959 ± 2.663
6.263LysThr: 6.263 ± 2.151
4.175LysVal: 4.175 ± 1.252
1.392LysTrp: 1.392 ± 1.111
4.175LysTyr: 4.175 ± 2.144
0.0LysXaa: 0.0 ± 0.0
Leu
9.047LeuAla: 9.047 ± 1.263
0.696LeuCys: 0.696 ± 1.424
6.263LeuAsp: 6.263 ± 2.063
7.655LeuGlu: 7.655 ± 0.953
4.175LeuPhe: 4.175 ± 2.236
5.567LeuGly: 5.567 ± 3.228
2.088LeuHis: 2.088 ± 0.978
2.088LeuIle: 2.088 ± 1.118
2.088LeuLys: 2.088 ± 2.584
7.655LeuLeu: 7.655 ± 2.281
3.479LeuMet: 3.479 ± 1.113
3.479LeuAsn: 3.479 ± 1.113
4.871LeuPro: 4.871 ± 2.609
3.479LeuGln: 3.479 ± 1.051
2.784LeuArg: 2.784 ± 1.491
6.263LeuSer: 6.263 ± 1.976
3.479LeuThr: 3.479 ± 0.866
8.351LeuVal: 8.351 ± 2.487
0.696LeuTrp: 0.696 ± 0.373
1.392LeuTyr: 1.392 ± 0.745
0.0LeuXaa: 0.0 ± 0.0
Met
2.784MetAla: 2.784 ± 1.491
0.0MetCys: 0.0 ± 0.0
2.784MetAsp: 2.784 ± 1.239
1.392MetGlu: 1.392 ± 0.745
0.0MetPhe: 0.0 ± 0.0
0.696MetGly: 0.696 ± 0.373
0.0MetHis: 0.0 ± 0.0
1.392MetIle: 1.392 ± 0.745
1.392MetLys: 1.392 ± 0.745
0.696MetLeu: 0.696 ± 1.424
0.0MetMet: 0.0 ± 0.0
0.696MetAsn: 0.696 ± 0.373
2.088MetPro: 2.088 ± 0.978
2.088MetGln: 2.088 ± 1.118
2.784MetArg: 2.784 ± 1.239
2.784MetSer: 2.784 ± 0.979
2.088MetThr: 2.088 ± 2.429
2.784MetVal: 2.784 ± 0.979
1.392MetTrp: 1.392 ± 1.111
0.696MetTyr: 0.696 ± 0.373
0.0MetXaa: 0.0 ± 0.0
Asn
2.784AsnAla: 2.784 ± 1.239
0.0AsnCys: 0.0 ± 0.0
1.392AsnAsp: 1.392 ± 0.745
2.784AsnGlu: 2.784 ± 1.491
3.479AsnPhe: 3.479 ± 2.06
2.088AsnGly: 2.088 ± 1.118
0.696AsnHis: 0.696 ± 0.373
0.696AsnIle: 0.696 ± 1.424
1.392AsnLys: 1.392 ± 0.745
4.175AsnLeu: 4.175 ± 0.494
0.696AsnMet: 0.696 ± 0.373
0.0AsnAsn: 0.0 ± 0.0
3.479AsnPro: 3.479 ± 1.051
3.479AsnGln: 3.479 ± 1.051
3.479AsnArg: 3.479 ± 1.051
3.479AsnSer: 3.479 ± 0.866
2.088AsnThr: 2.088 ± 1.005
2.088AsnVal: 2.088 ± 1.005
1.392AsnTrp: 1.392 ± 1.111
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.567ProAla: 5.567 ± 1.935
0.0ProCys: 0.0 ± 0.0
4.871ProAsp: 4.871 ± 1.622
4.175ProGlu: 4.175 ± 1.34
3.479ProPhe: 3.479 ± 2.374
0.696ProGly: 0.696 ± 0.373
2.088ProHis: 2.088 ± 1.612
2.784ProIle: 2.784 ± 2.349
2.088ProLys: 2.088 ± 1.118
6.263ProLeu: 6.263 ± 2.935
1.392ProMet: 1.392 ± 2.443
2.784ProAsn: 2.784 ± 0.958
5.567ProPro: 5.567 ± 1.427
3.479ProGln: 3.479 ± 2.154
3.479ProArg: 3.479 ± 0.866
3.479ProSer: 3.479 ± 0.866
3.479ProThr: 3.479 ± 0.866
3.479ProVal: 3.479 ± 0.866
1.392ProTrp: 1.392 ± 1.175
2.088ProTyr: 2.088 ± 1.118
0.0ProXaa: 0.0 ± 0.0
Gln
2.088GlnAla: 2.088 ± 1.118
0.0GlnCys: 0.0 ± 0.0
2.088GlnAsp: 2.088 ± 1.118
2.088GlnGlu: 2.088 ± 1.118
0.696GlnPhe: 0.696 ± 1.337
2.784GlnGly: 2.784 ± 0.979
1.392GlnHis: 1.392 ± 0.745
1.392GlnIle: 1.392 ± 0.745
4.871GlnLys: 4.871 ± 3.321
1.392GlnLeu: 1.392 ± 1.111
0.696GlnMet: 0.696 ± 0.373
0.0GlnAsn: 0.0 ± 0.0
4.175GlnPro: 4.175 ± 2.144
2.088GlnGln: 2.088 ± 1.005
2.088GlnArg: 2.088 ± 1.005
2.784GlnSer: 2.784 ± 1.491
1.392GlnThr: 1.392 ± 0.745
0.696GlnVal: 0.696 ± 0.373
0.0GlnTrp: 0.0 ± 0.0
1.392GlnTyr: 1.392 ± 0.745
0.0GlnXaa: 0.0 ± 0.0
Arg
2.088ArgAla: 2.088 ± 0.978
0.0ArgCys: 0.0 ± 0.0
5.567ArgAsp: 5.567 ± 1.427
1.392ArgGlu: 1.392 ± 1.111
2.784ArgPhe: 2.784 ± 2.349
3.479ArgGly: 3.479 ± 1.864
1.392ArgHis: 1.392 ± 0.745
2.088ArgIle: 2.088 ± 1.118
6.263ArgLys: 6.263 ± 2.106
2.784ArgLeu: 2.784 ± 1.491
0.696ArgMet: 0.696 ± 0.373
3.479ArgAsn: 3.479 ± 1.051
1.392ArgPro: 1.392 ± 0.745
1.392ArgGln: 1.392 ± 0.745
3.479ArgArg: 3.479 ± 1.051
1.392ArgSer: 1.392 ± 1.175
2.784ArgThr: 2.784 ± 1.239
4.871ArgVal: 4.871 ± 1.72
0.0ArgTrp: 0.0 ± 0.0
2.088ArgTyr: 2.088 ± 1.005
0.0ArgXaa: 0.0 ± 0.0
Ser
4.175SerAla: 4.175 ± 1.34
2.784SerCys: 2.784 ± 0.958
2.088SerAsp: 2.088 ± 1.612
2.088SerGlu: 2.088 ± 1.118
1.392SerPhe: 1.392 ± 0.745
4.175SerGly: 4.175 ± 1.252
0.696SerHis: 0.696 ± 1.337
2.088SerIle: 2.088 ± 0.978
5.567SerLys: 5.567 ± 0.252
6.959SerLeu: 6.959 ± 4.359
2.088SerMet: 2.088 ± 0.978
5.567SerAsn: 5.567 ± 0.252
4.871SerPro: 4.871 ± 2.851
0.696SerGln: 0.696 ± 1.337
2.088SerArg: 2.088 ± 2.584
4.175SerSer: 4.175 ± 2.01
4.175SerThr: 4.175 ± 2.039
6.263SerVal: 6.263 ± 1.976
0.696SerTrp: 0.696 ± 1.337
2.784SerTyr: 2.784 ± 2.349
0.0SerXaa: 0.0 ± 0.0
Thr
5.567ThrAla: 5.567 ± 2.478
1.392ThrCys: 1.392 ± 1.111
3.479ThrAsp: 3.479 ± 2.154
4.871ThrGlu: 4.871 ± 2.609
2.784ThrPhe: 2.784 ± 1.239
4.175ThrGly: 4.175 ± 4.747
2.088ThrHis: 2.088 ± 1.118
3.479ThrIle: 3.479 ± 1.051
6.959ThrLys: 6.959 ± 0.997
6.959ThrLeu: 6.959 ± 2.922
2.088ThrMet: 2.088 ± 1.118
3.479ThrAsn: 3.479 ± 0.866
6.263ThrPro: 6.263 ± 2.763
0.696ThrGln: 0.696 ± 1.337
4.175ThrArg: 4.175 ± 1.34
4.175ThrSer: 4.175 ± 0.494
6.263ThrThr: 6.263 ± 2.151
4.175ThrVal: 4.175 ± 1.34
1.392ThrTrp: 1.392 ± 0.745
2.088ThrTyr: 2.088 ± 0.978
0.0ThrXaa: 0.0 ± 0.0
Val
5.567ValAla: 5.567 ± 1.916
0.696ValCys: 0.696 ± 1.424
4.871ValAsp: 4.871 ± 3.338
4.175ValGlu: 4.175 ± 1.252
3.479ValPhe: 3.479 ± 1.113
2.784ValGly: 2.784 ± 1.491
0.696ValHis: 0.696 ± 0.373
2.784ValIle: 2.784 ± 2.221
5.567ValLys: 5.567 ± 2.982
5.567ValLeu: 5.567 ± 1.935
2.784ValMet: 2.784 ± 0.979
2.784ValAsn: 2.784 ± 0.958
4.175ValPro: 4.175 ± 1.34
0.696ValGln: 0.696 ± 0.373
3.479ValArg: 3.479 ± 2.374
6.263ValSer: 6.263 ± 4.836
6.959ValThr: 6.959 ± 2.101
4.175ValVal: 4.175 ± 1.252
0.0ValTrp: 0.0 ± 0.0
2.088ValTyr: 2.088 ± 1.118
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.392TrpAsp: 1.392 ± 0.745
0.0TrpGlu: 0.0 ± 0.0
0.696TrpPhe: 0.696 ± 1.337
0.0TrpGly: 0.0 ± 0.0
0.696TrpHis: 0.696 ± 0.373
0.696TrpIle: 0.696 ± 0.373
0.696TrpLys: 0.696 ± 0.373
1.392TrpLeu: 1.392 ± 0.745
0.696TrpMet: 0.696 ± 0.373
0.696TrpAsn: 0.696 ± 1.337
0.0TrpPro: 0.0 ± 0.0
0.696TrpGln: 0.696 ± 1.337
2.088TrpArg: 2.088 ± 2.429
1.392TrpSer: 1.392 ± 0.745
2.088TrpThr: 2.088 ± 2.429
4.871TrpVal: 4.871 ± 1.52
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.784TyrAla: 2.784 ± 0.958
0.0TyrCys: 0.0 ± 0.0
1.392TyrAsp: 1.392 ± 1.175
1.392TyrGlu: 1.392 ± 0.745
0.696TyrPhe: 0.696 ± 1.337
2.088TyrGly: 2.088 ± 1.005
0.0TyrHis: 0.0 ± 0.0
0.696TyrIle: 0.696 ± 1.424
2.784TyrLys: 2.784 ± 0.958
2.088TyrLeu: 2.088 ± 0.978
0.696TyrMet: 0.696 ± 1.337
0.696TyrAsn: 0.696 ± 0.373
2.088TyrPro: 2.088 ± 1.118
0.696TyrGln: 0.696 ± 0.373
1.392TyrArg: 1.392 ± 1.175
2.784TyrSer: 2.784 ± 1.239
4.175TyrThr: 4.175 ± 0.494
2.784TyrVal: 2.784 ± 0.958
0.696TyrTrp: 0.696 ± 0.373
0.696TyrTyr: 0.696 ± 1.337
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1438 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski