Amino acid dipepetide frequency for Botryotinia narcissicola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.176AlaAla: 7.176 ± 0.055	0.927AlaCys: 0.927 ± 0.014	3.632AlaAsp: 3.632 ± 0.029	4.722AlaGlu: 4.722 ± 0.041	2.881AlaPhe: 2.881 ± 0.025	5.103AlaGly: 5.103 ± 0.034	1.54AlaHis: 1.54 ± 0.016	4.354AlaIle: 4.354 ± 0.031	4.179AlaLys: 4.179 ± 0.032	6.764AlaLeu: 6.764 ± 0.05	1.809AlaMet: 1.809 ± 0.019	3.007AlaAsn: 3.007 ± 0.025	4.238AlaPro: 4.238 ± 0.039	3.054AlaGln: 3.054 ± 0.027	4.075AlaArg: 4.075 ± 0.031	6.883AlaSer: 6.883 ± 0.048	4.901AlaThr: 4.901 ± 0.034	4.435AlaVal: 4.435 ± 0.033	0.996AlaTrp: 0.996 ± 0.014	2.018AlaTyr: 2.018 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.843CysAla: 0.843 ± 0.013	0.227CysCys: 0.227 ± 0.008	0.646CysAsp: 0.646 ± 0.011	0.626CysGlu: 0.626 ± 0.012	0.512CysPhe: 0.512 ± 0.011	0.914CysGly: 0.914 ± 0.015	0.292CysHis: 0.292 ± 0.007	0.722CysIle: 0.722 ± 0.013	0.583CysLys: 0.583 ± 0.01	1.158CysLeu: 1.158 ± 0.016	0.269CysMet: 0.269 ± 0.007	0.462CysAsn: 0.462 ± 0.01	0.633CysPro: 0.633 ± 0.013	0.416CysGln: 0.416 ± 0.009	0.635CysArg: 0.635 ± 0.012	0.93CysSer: 0.93 ± 0.014	0.7CysThr: 0.7 ± 0.011	0.735CysVal: 0.735 ± 0.013	0.184CysTrp: 0.184 ± 0.005	0.352CysTyr: 0.352 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.085AspAla: 4.085 ± 0.026	0.639AspCys: 0.639 ± 0.013	4.117AspAsp: 4.117 ± 0.048	4.626AspGlu: 4.626 ± 0.042	2.276AspPhe: 2.276 ± 0.02	3.835AspGly: 3.835 ± 0.028	1.172AspHis: 1.172 ± 0.017	3.341AspIle: 3.341 ± 0.023	2.479AspLys: 2.479 ± 0.021	4.941AspLeu: 4.941 ± 0.031	1.25AspMet: 1.25 ± 0.016	2.1AspAsn: 2.1 ± 0.02	2.927AspPro: 2.927 ± 0.022	1.759AspGln: 1.759 ± 0.022	2.757AspArg: 2.757 ± 0.032	4.344AspSer: 4.344 ± 0.034	2.984AspThr: 2.984 ± 0.026	3.433AspVal: 3.433 ± 0.024	0.845AspTrp: 0.845 ± 0.012	1.622AspTyr: 1.622 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	4.888GluAla: 4.888 ± 0.035	0.637GluCys: 0.637 ± 0.012	4.421GluAsp: 4.421 ± 0.043	6.323GluGlu: 6.323 ± 0.063	2.118GluPhe: 2.118 ± 0.019	3.983GluGly: 3.983 ± 0.034	1.324GluHis: 1.324 ± 0.019	3.781GluIle: 3.781 ± 0.031	4.577GluLys: 4.577 ± 0.045	5.167GluLeu: 5.167 ± 0.04	1.696GluMet: 1.696 ± 0.019	2.947GluAsn: 2.947 ± 0.027	2.579GluPro: 2.579 ± 0.032	2.35GluGln: 2.35 ± 0.027	4.067GluArg: 4.067 ± 0.046	4.824GluSer: 4.824 ± 0.044	3.545GluThr: 3.545 ± 0.029	3.741GluVal: 3.741 ± 0.027	0.907GluTrp: 0.907 ± 0.014	1.799GluTyr: 1.799 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	2.822PheAla: 2.822 ± 0.028	0.549PheCys: 0.549 ± 0.01	2.284PheAsp: 2.284 ± 0.022	2.351PheGlu: 2.351 ± 0.021	1.59PhePhe: 1.59 ± 0.021	2.879PheGly: 2.879 ± 0.032	0.883PheHis: 0.883 ± 0.014	1.963PheIle: 1.963 ± 0.022	1.734PheLys: 1.734 ± 0.019	3.431PheLeu: 3.431 ± 0.03	0.846PheMet: 0.846 ± 0.012	1.616PheAsn: 1.616 ± 0.021	1.968PhePro: 1.968 ± 0.02	1.418PheGln: 1.418 ± 0.018	1.822PheArg: 1.822 ± 0.019	3.139PheSer: 3.139 ± 0.025	2.275PheThr: 2.275 ± 0.024	2.277PheVal: 2.277 ± 0.022	0.636PheTrp: 0.636 ± 0.011	1.117PheTyr: 1.117 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	4.693GlyAla: 4.693 ± 0.039	0.835GlyCys: 0.835 ± 0.013	3.516GlyAsp: 3.516 ± 0.031	3.915GlyGlu: 3.915 ± 0.027	2.75GlyPhe: 2.75 ± 0.027	5.741GlyGly: 5.741 ± 0.054	1.528GlyHis: 1.528 ± 0.02	3.787GlyIle: 3.787 ± 0.034	3.912GlyLys: 3.912 ± 0.035	5.666GlyLeu: 5.666 ± 0.042	1.711GlyMet: 1.711 ± 0.022	2.966GlyAsn: 2.966 ± 0.027	2.91GlyPro: 2.91 ± 0.027	2.246GlyGln: 2.246 ± 0.024	3.766GlyArg: 3.766 ± 0.034	5.736GlySer: 5.736 ± 0.044	4.001GlyThr: 4.001 ± 0.031	4.166GlyVal: 4.166 ± 0.035	1.111GlyTrp: 1.111 ± 0.015	2.168GlyTyr: 2.168 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.566HisAla: 1.566 ± 0.018	0.314HisCys: 0.314 ± 0.008	1.262HisAsp: 1.262 ± 0.015	1.368HisGlu: 1.368 ± 0.019	0.897HisPhe: 0.897 ± 0.014	1.557HisGly: 1.557 ± 0.02	0.784HisHis: 0.784 ± 0.016	1.256HisIle: 1.256 ± 0.015	1.007HisLys: 1.007 ± 0.016	2.042HisLeu: 2.042 ± 0.02	0.492HisMet: 0.492 ± 0.009	0.964HisAsn: 0.964 ± 0.014	1.505HisPro: 1.505 ± 0.018	0.962HisGln: 0.962 ± 0.014	1.349HisArg: 1.349 ± 0.018	1.923HisSer: 1.923 ± 0.024	1.321HisThr: 1.321 ± 0.02	1.234HisVal: 1.234 ± 0.016	0.296HisTrp: 0.296 ± 0.007	0.7HisTyr: 0.7 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.304IleAla: 4.304 ± 0.03	0.797IleCys: 0.797 ± 0.013	3.191IleAsp: 3.191 ± 0.025	3.483IleGlu: 3.483 ± 0.028	2.275IlePhe: 2.275 ± 0.022	3.464IleGly: 3.464 ± 0.029	1.3IleHis: 1.3 ± 0.016	3.063IleIle: 3.063 ± 0.031	2.736IleLys: 2.736 ± 0.025	5.047IleLeu: 5.047 ± 0.04	1.144IleMet: 1.144 ± 0.015	2.247IleAsn: 2.247 ± 0.022	3.499IlePro: 3.499 ± 0.027	2.097IleGln: 2.097 ± 0.021	2.799IleArg: 2.799 ± 0.026	4.779IleSer: 4.779 ± 0.03	3.339IleThr: 3.339 ± 0.028	3.385IleVal: 3.385 ± 0.025	0.788IleTrp: 0.788 ± 0.013	1.609IleTyr: 1.609 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.311LysAla: 4.311 ± 0.036	0.577LysCys: 0.577 ± 0.013	3.165LysAsp: 3.165 ± 0.031	4.131LysGlu: 4.131 ± 0.04	1.761LysPhe: 1.761 ± 0.019	3.3LysGly: 3.3 ± 0.026	1.196LysHis: 1.196 ± 0.016	2.976LysIle: 2.976 ± 0.027	4.116LysLys: 4.116 ± 0.048	4.468LysLeu: 4.468 ± 0.034	1.218LysMet: 1.218 ± 0.017	2.33LysAsn: 2.33 ± 0.021	2.79LysPro: 2.79 ± 0.029	1.899LysGln: 1.899 ± 0.022	3.603LysArg: 3.603 ± 0.031	4.442LysSer: 4.442 ± 0.033	3.167LysThr: 3.167 ± 0.026	3.142LysVal: 3.142 ± 0.026	0.756LysTrp: 0.756 ± 0.013	1.569LysTyr: 1.569 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	6.826LeuAla: 6.826 ± 0.041	1.116LeuCys: 1.116 ± 0.016	4.805LeuAsp: 4.805 ± 0.036	5.6LeuGlu: 5.6 ± 0.039	3.201LeuPhe: 3.201 ± 0.03	5.559LeuGly: 5.559 ± 0.035	2.051LeuHis: 2.051 ± 0.02	4.289LeuIle: 4.289 ± 0.033	4.667LeuLys: 4.667 ± 0.036	7.753LeuLeu: 7.753 ± 0.054	1.817LeuMet: 1.817 ± 0.02	3.477LeuAsn: 3.477 ± 0.031	5.21LeuPro: 5.21 ± 0.032	3.617LeuGln: 3.617 ± 0.029	5.091LeuArg: 5.091 ± 0.038	7.319LeuSer: 7.319 ± 0.046	4.785LeuThr: 4.785 ± 0.034	4.822LeuVal: 4.822 ± 0.039	1.111LeuTrp: 1.111 ± 0.018	2.312LeuTyr: 2.312 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.063MetAla: 2.063 ± 0.02	0.246MetCys: 0.246 ± 0.007	1.287MetAsp: 1.287 ± 0.017	1.512MetGlu: 1.512 ± 0.017	0.782MetPhe: 0.782 ± 0.015	1.581MetGly: 1.581 ± 0.02	0.473MetHis: 0.473 ± 0.01	1.171MetIle: 1.171 ± 0.014	1.231MetLys: 1.231 ± 0.017	1.763MetLeu: 1.763 ± 0.019	0.624MetMet: 0.624 ± 0.01	1.003MetAsn: 1.003 ± 0.016	1.194MetPro: 1.194 ± 0.016	0.859MetGln: 0.859 ± 0.013	1.244MetArg: 1.244 ± 0.015	2.026MetSer: 2.026 ± 0.019	1.318MetThr: 1.318 ± 0.017	1.297MetVal: 1.297 ± 0.018	0.251MetTrp: 0.251 ± 0.007	0.556MetTyr: 0.556 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.207AsnAla: 3.207 ± 0.028	0.503AsnCys: 0.503 ± 0.01	2.278AsnAsp: 2.278 ± 0.022	2.501AsnGlu: 2.501 ± 0.022	1.669AsnPhe: 1.669 ± 0.018	3.408AsnGly: 3.408 ± 0.03	1.035AsnHis: 1.035 ± 0.015	2.528AsnIle: 2.528 ± 0.025	1.932AsnLys: 1.932 ± 0.02	3.678AsnLeu: 3.678 ± 0.027	0.961AsnMet: 0.961 ± 0.016	1.975AsnAsn: 1.975 ± 0.025	2.638AsnPro: 2.638 ± 0.021	1.549AsnGln: 1.549 ± 0.021	2.097AsnArg: 2.097 ± 0.022	3.665AsnSer: 3.665 ± 0.03	2.741AsnThr: 2.741 ± 0.025	2.458AsnVal: 2.458 ± 0.023	0.593AsnTrp: 0.593 ± 0.011	1.277AsnTyr: 1.277 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.348ProAla: 4.348 ± 0.039	0.449ProCys: 0.449 ± 0.01	2.745ProAsp: 2.745 ± 0.024	3.617ProGlu: 3.617 ± 0.034	1.969ProPhe: 1.969 ± 0.021	3.415ProGly: 3.415 ± 0.031	1.246ProHis: 1.246 ± 0.016	3.023ProIle: 3.023 ± 0.026	2.909ProLys: 2.909 ± 0.029	4.535ProLeu: 4.535 ± 0.037	1.047ProMet: 1.047 ± 0.017	2.412ProAsn: 2.412 ± 0.022	4.652ProPro: 4.652 ± 0.063	2.434ProGln: 2.434 ± 0.032	3.109ProArg: 3.109 ± 0.033	6.051ProSer: 6.051 ± 0.049	4.039ProThr: 4.039 ± 0.035	3.197ProVal: 3.197 ± 0.028	0.639ProTrp: 0.639 ± 0.011	1.497ProTyr: 1.497 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.051GlnAla: 3.051 ± 0.03	0.413GlnCys: 0.413 ± 0.009	1.957GlnAsp: 1.957 ± 0.021	2.417GlnGlu: 2.417 ± 0.027	1.312GlnPhe: 1.312 ± 0.015	2.179GlnGly: 2.179 ± 0.025	0.968GlnHis: 0.968 ± 0.015	2.105GlnIle: 2.105 ± 0.017	2.27GlnLys: 2.27 ± 0.022	3.11GlnLeu: 3.11 ± 0.027	0.89GlnMet: 0.89 ± 0.014	1.856GlnAsn: 1.856 ± 0.022	2.182GlnPro: 2.182 ± 0.027	2.163GlnGln: 2.163 ± 0.044	2.349GlnArg: 2.349 ± 0.026	3.304GlnSer: 3.304 ± 0.034	2.306GlnThr: 2.306 ± 0.022	2.019GlnVal: 2.019 ± 0.019	0.519GlnTrp: 0.519 ± 0.01	1.211GlnTyr: 1.211 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	3.926ArgAla: 3.926 ± 0.029	0.623ArgCys: 0.623 ± 0.012	3.101ArgAsp: 3.101 ± 0.031	3.952ArgGlu: 3.952 ± 0.04	1.946ArgPhe: 1.946 ± 0.019	3.624ArgGly: 3.624 ± 0.038	1.302ArgHis: 1.302 ± 0.016	2.981ArgIle: 2.981 ± 0.024	3.745ArgLys: 3.745 ± 0.036	4.652ArgLeu: 4.652 ± 0.034	1.292ArgMet: 1.292 ± 0.016	2.539ArgAsn: 2.539 ± 0.023	2.951ArgPro: 2.951 ± 0.033	2.289ArgGln: 2.289 ± 0.024	4.427ArgArg: 4.427 ± 0.044	4.636ArgSer: 4.636 ± 0.044	3.053ArgThr: 3.053 ± 0.025	2.952ArgVal: 2.952 ± 0.026	0.8ArgTrp: 0.8 ± 0.012	1.558ArgTyr: 1.558 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.304SerAla: 6.304 ± 0.044	0.897SerCys: 0.897 ± 0.013	4.359SerAsp: 4.359 ± 0.031	4.642SerGlu: 4.642 ± 0.036	3.224SerPhe: 3.224 ± 0.025	5.616SerGly: 5.616 ± 0.047	2.067SerHis: 2.067 ± 0.022	4.933SerIle: 4.933 ± 0.034	4.508SerLys: 4.508 ± 0.035	7.262SerLeu: 7.262 ± 0.044	1.861SerMet: 1.861 ± 0.018	3.913SerAsn: 3.913 ± 0.031	5.699SerPro: 5.699 ± 0.053	3.463SerGln: 3.463 ± 0.036	4.867SerArg: 4.867 ± 0.041	10.206SerSer: 10.206 ± 0.089	6.522SerThr: 6.522 ± 0.06	4.501SerVal: 4.501 ± 0.032	1.069SerTrp: 1.069 ± 0.016	2.281SerTyr: 2.281 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	4.744ThrAla: 4.744 ± 0.031	0.746ThrCys: 0.746 ± 0.013	2.771ThrAsp: 2.771 ± 0.025	3.263ThrGlu: 3.263 ± 0.029	2.403ThrPhe: 2.403 ± 0.024	4.094ThrGly: 4.094 ± 0.038	1.325ThrHis: 1.325 ± 0.017	3.683ThrIle: 3.683 ± 0.031	3.031ThrLys: 3.031 ± 0.026	5.209ThrLeu: 5.209 ± 0.032	1.233ThrMet: 1.233 ± 0.014	2.569ThrAsn: 2.569 ± 0.023	4.506ThrPro: 4.506 ± 0.045	2.179ThrGln: 2.179 ± 0.022	3.005ThrArg: 3.005 ± 0.028	6.283ThrSer: 6.283 ± 0.06	4.715ThrThr: 4.715 ± 0.046	3.408ThrVal: 3.408 ± 0.027	0.816ThrTrp: 0.816 ± 0.013	1.722ThrTyr: 1.722 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.554ValAla: 4.554 ± 0.033	0.715ValCys: 0.715 ± 0.012	3.452ValAsp: 3.452 ± 0.028	4.066ValGlu: 4.066 ± 0.028	2.287ValPhe: 2.287 ± 0.023	3.836ValGly: 3.836 ± 0.033	1.244ValHis: 1.244 ± 0.016	3.035ValIle: 3.035 ± 0.024	3.127ValLys: 3.127 ± 0.027	5.024ValLeu: 5.024 ± 0.038	1.317ValMet: 1.317 ± 0.017	2.296ValAsn: 2.296 ± 0.023	3.234ValPro: 3.234 ± 0.028	2.159ValGln: 2.159 ± 0.02	2.956ValArg: 2.956 ± 0.026	4.472ValSer: 4.472 ± 0.032	3.356ValThr: 3.356 ± 0.028	3.935ValVal: 3.935 ± 0.032	0.795ValTrp: 0.795 ± 0.015	1.643ValTyr: 1.643 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	0.965TrpAla: 0.965 ± 0.015	0.192TrpCys: 0.192 ± 0.006	0.843TrpAsp: 0.843 ± 0.015	0.896TrpGlu: 0.896 ± 0.015	0.518TrpPhe: 0.518 ± 0.01	0.947TrpGly: 0.947 ± 0.015	0.322TrpHis: 0.322 ± 0.008	0.803TrpIle: 0.803 ± 0.013	0.878TrpLys: 0.878 ± 0.013	1.194TrpLeu: 1.194 ± 0.017	0.375TrpMet: 0.375 ± 0.008	0.685TrpAsn: 0.685 ± 0.011	0.509TrpPro: 0.509 ± 0.01	0.511TrpGln: 0.511 ± 0.012	0.82TrpArg: 0.82 ± 0.014	1.01TrpSer: 1.01 ± 0.015	0.85TrpThr: 0.85 ± 0.012	0.812TrpVal: 0.812 ± 0.012	0.258TrpTrp: 0.258 ± 0.008	0.417TrpTyr: 0.417 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.017TyrAla: 2.017 ± 0.02	0.437TyrCys: 0.437 ± 0.009	1.696TyrAsp: 1.696 ± 0.018	1.664TyrGlu: 1.664 ± 0.02	1.23TyrPhe: 1.23 ± 0.016	2.09TyrGly: 2.09 ± 0.022	0.745TyrHis: 0.745 ± 0.013	1.552TyrIle: 1.552 ± 0.02	1.298TyrLys: 1.298 ± 0.018	2.565TyrLeu: 2.565 ± 0.026	0.631TyrMet: 0.631 ± 0.011	1.33TyrAsn: 1.33 ± 0.017	1.506TyrPro: 1.506 ± 0.017	1.158TyrGln: 1.158 ± 0.016	1.51TyrArg: 1.51 ± 0.017	2.223TyrSer: 2.223 ± 0.022	1.786TyrThr: 1.786 ± 0.019	1.553TyrVal: 1.553 ± 0.016	0.436TyrTrp: 0.436 ± 0.01	0.98TyrTyr: 0.98 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12236 proteins (5465297 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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