Amino acid dipepetide frequency for Beihai picorna-like virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.701AlaAla: 5.701 ± 1.345
1.52AlaCys: 1.52 ± 0.198
5.321AlaAsp: 5.321 ± 0.27
4.941AlaGlu: 4.941 ± 0.162
3.801AlaPhe: 3.801 ± 0.816
4.181AlaGly: 4.181 ± 1.542
1.52AlaHis: 1.52 ± 0.198
2.661AlaIle: 2.661 ± 0.186
3.421AlaLys: 3.421 ± 1.248
6.842AlaLeu: 6.842 ± 1.212
2.281AlaMet: 2.281 ± 0.297
4.181AlaAsn: 4.181 ± 0.9
3.421AlaPro: 3.421 ± 0.036
2.661AlaGln: 2.661 ± 0.186
4.941AlaArg: 4.941 ± 0.804
5.321AlaSer: 5.321 ± 0.27
4.181AlaThr: 4.181 ± 2.184
4.561AlaVal: 4.561 ± 0.048
0.76AlaTrp: 0.76 ± 0.222
2.661AlaTyr: 2.661 ± 0.186
0.0AlaXaa: 0.0 ± 0.0
Cys
0.38CysAla: 0.38 ± 0.21
0.0CysCys: 0.0 ± 0.0
1.14CysAsp: 1.14 ± 0.012
0.76CysGlu: 0.76 ± 0.42
1.14CysPhe: 1.14 ± 0.63
1.52CysGly: 1.52 ± 0.84
0.0CysHis: 0.0 ± 0.0
0.76CysIle: 0.76 ± 0.222
0.76CysLys: 0.76 ± 0.42
0.38CysLeu: 0.38 ± 0.21
0.38CysMet: 0.38 ± 0.21
0.76CysAsn: 0.76 ± 0.222
2.281CysPro: 2.281 ± 0.618
0.0CysGln: 0.0 ± 0.0
0.38CysArg: 0.38 ± 0.432
1.52CysSer: 1.52 ± 0.84
0.38CysThr: 0.38 ± 0.21
0.38CysVal: 0.38 ± 0.21
0.0CysTrp: 0.0 ± 0.0
0.76CysTyr: 0.76 ± 0.222
0.0CysXaa: 0.0 ± 0.0
Asp
4.941AspAla: 4.941 ± 0.162
0.38AspCys: 0.38 ± 0.21
3.801AspAsp: 3.801 ± 0.174
4.181AspGlu: 4.181 ± 1.026
2.661AspPhe: 2.661 ± 1.098
3.041AspGly: 3.041 ± 0.396
0.38AspHis: 0.38 ± 0.432
2.661AspIle: 2.661 ± 0.456
2.661AspLys: 2.661 ± 0.828
6.081AspLeu: 6.081 ± 0.15
1.9AspMet: 1.9 ± 0.234
1.9AspAsn: 1.9 ± 0.234
2.661AspPro: 2.661 ± 2.382
2.281AspGln: 2.281 ± 1.308
2.281AspArg: 2.281 ± 0.024
3.801AspSer: 3.801 ± 0.468
1.9AspThr: 1.9 ± 2.16
4.941AspVal: 4.941 ± 0.162
0.76AspTrp: 0.76 ± 0.42
2.661AspTyr: 2.661 ± 1.47
0.0AspXaa: 0.0 ± 0.0
Glu
6.842GluAla: 6.842 ± 1.212
1.52GluCys: 1.52 ± 0.84
2.281GluAsp: 2.281 ± 0.666
4.181GluGlu: 4.181 ± 0.384
2.661GluPhe: 2.661 ± 1.47
3.801GluGly: 3.801 ± 0.468
0.76GluHis: 0.76 ± 0.222
4.561GluIle: 4.561 ± 0.69
2.661GluLys: 2.661 ± 0.186
6.081GluLeu: 6.081 ± 1.434
0.38GluMet: 0.38 ± 0.21
1.14GluAsn: 1.14 ± 0.012
3.421GluPro: 3.421 ± 0.036
1.9GluGln: 1.9 ± 1.05
2.281GluArg: 2.281 ± 0.024
3.801GluSer: 3.801 ± 0.816
3.801GluThr: 3.801 ± 0.468
4.561GluVal: 4.561 ± 0.594
1.14GluTrp: 1.14 ± 0.63
2.661GluTyr: 2.661 ± 0.186
0.0GluXaa: 0.0 ± 0.0
Phe
4.941PheAla: 4.941 ± 1.446
0.38PheCys: 0.38 ± 0.21
3.041PheAsp: 3.041 ± 1.038
3.801PheGlu: 3.801 ± 0.468
3.041PhePhe: 3.041 ± 1.53
4.941PheGly: 4.941 ± 1.122
1.14PheHis: 1.14 ± 0.654
1.14PheIle: 1.14 ± 0.63
1.14PheLys: 1.14 ± 0.63
6.461PheLeu: 6.461 ± 0.36
2.281PheMet: 2.281 ± 0.618
2.661PheAsn: 2.661 ± 0.186
2.281PhePro: 2.281 ± 0.666
0.76PheGln: 0.76 ± 0.42
0.38PheArg: 0.38 ± 0.432
2.281PheSer: 2.281 ± 1.26
3.801PheThr: 3.801 ± 1.11
3.041PheVal: 3.041 ± 0.396
1.14PheTrp: 1.14 ± 0.654
0.38PheTyr: 0.38 ± 0.21
0.0PheXaa: 0.0 ± 0.0
Gly
4.181GlyAla: 4.181 ± 1.542
1.52GlyCys: 1.52 ± 0.198
3.801GlyAsp: 3.801 ± 0.468
3.421GlyGlu: 3.421 ± 1.962
3.041GlyPhe: 3.041 ± 0.396
3.421GlyGly: 3.421 ± 1.962
0.38GlyHis: 0.38 ± 0.21
5.321GlyIle: 5.321 ± 0.27
3.421GlyLys: 3.421 ± 1.248
3.801GlyLeu: 3.801 ± 0.468
1.14GlyMet: 1.14 ± 0.012
4.561GlyAsn: 4.561 ± 0.048
2.661GlyPro: 2.661 ± 0.456
4.181GlyGln: 4.181 ± 1.542
3.801GlyArg: 3.801 ± 1.11
3.801GlySer: 3.801 ± 0.816
5.701GlyThr: 5.701 ± 1.345
4.941GlyVal: 4.941 ± 0.804
1.52GlyTrp: 1.52 ± 1.728
1.9GlyTyr: 1.9 ± 0.876
0.0GlyXaa: 0.0 ± 0.0
His
1.52HisAla: 1.52 ± 0.444
0.38HisCys: 0.38 ± 0.21
0.38HisAsp: 0.38 ± 0.21
1.14HisGlu: 1.14 ± 0.63
2.281HisPhe: 2.281 ± 0.024
0.38HisGly: 0.38 ± 0.21
0.76HisHis: 0.76 ± 0.222
1.14HisIle: 1.14 ± 0.012
1.52HisLys: 1.52 ± 1.086
1.14HisLeu: 1.14 ± 0.63
0.0HisMet: 0.0 ± 0.0
0.38HisAsn: 0.38 ± 0.432
1.9HisPro: 1.9 ± 0.234
0.76HisGln: 0.76 ± 0.42
0.38HisArg: 0.38 ± 0.21
1.52HisSer: 1.52 ± 0.84
0.38HisThr: 0.38 ± 0.432
1.9HisVal: 1.9 ± 0.408
0.76HisTrp: 0.76 ± 0.222
1.52HisTyr: 1.52 ± 0.198
0.0HisXaa: 0.0 ± 0.0
Ile
5.701IleAla: 5.701 ± 0.06
1.14IleCys: 1.14 ± 0.012
4.181IleAsp: 4.181 ± 0.384
3.041IleGlu: 3.041 ± 0.396
1.52IlePhe: 1.52 ± 0.84
3.421IleGly: 3.421 ± 0.606
0.76IleHis: 0.76 ± 0.222
3.421IleIle: 3.421 ± 1.248
3.041IleLys: 3.041 ± 0.888
3.421IleLeu: 3.421 ± 0.606
1.9IleMet: 1.9 ± 1.05
2.661IleAsn: 2.661 ± 0.186
0.38IlePro: 0.38 ± 0.21
3.041IleGln: 3.041 ± 1.53
3.041IleArg: 3.041 ± 0.246
4.181IleSer: 4.181 ± 0.384
4.181IleThr: 4.181 ± 0.258
3.801IleVal: 3.801 ± 0.816
0.76IleTrp: 0.76 ± 0.42
1.14IleTyr: 1.14 ± 0.63
0.0IleXaa: 0.0 ± 0.0
Lys
3.041LysAla: 3.041 ± 1.68
0.38LysCys: 0.38 ± 0.21
2.661LysAsp: 2.661 ± 1.47
3.801LysGlu: 3.801 ± 2.1
2.661LysPhe: 2.661 ± 0.186
1.9LysGly: 1.9 ± 0.408
1.14LysHis: 1.14 ± 0.63
4.561LysIle: 4.561 ± 1.236
3.801LysLys: 3.801 ± 2.1
1.9LysLeu: 1.9 ± 0.876
1.9LysMet: 1.9 ± 0.408
1.52LysAsn: 1.52 ± 0.84
2.661LysPro: 2.661 ± 0.456
1.52LysGln: 1.52 ± 0.198
2.661LysArg: 2.661 ± 0.186
4.941LysSer: 4.941 ± 0.162
3.421LysThr: 3.421 ± 0.606
3.801LysVal: 3.801 ± 2.1
0.76LysTrp: 0.76 ± 0.222
2.661LysTyr: 2.661 ± 0.186
0.0LysXaa: 0.0 ± 0.0
Leu
6.081LeuAla: 6.081 ± 2.076
0.76LeuCys: 0.76 ± 0.42
4.941LeuAsp: 4.941 ± 1.122
4.561LeuGlu: 4.561 ± 1.236
4.181LeuPhe: 4.181 ± 0.9
5.321LeuGly: 5.321 ± 1.555
2.661LeuHis: 2.661 ± 0.186
3.421LeuIle: 3.421 ± 0.606
3.801LeuLys: 3.801 ± 2.1
5.321LeuLeu: 5.321 ± 1.656
1.14LeuMet: 1.14 ± 0.012
4.561LeuAsn: 4.561 ± 0.69
1.52LeuPro: 1.52 ± 0.444
2.281LeuGln: 2.281 ± 0.024
3.801LeuArg: 3.801 ± 1.458
6.842LeuSer: 6.842 ± 0.715
6.842LeuThr: 6.842 ± 1.357
7.222LeuVal: 7.222 ± 2.706
0.76LeuTrp: 0.76 ± 0.864
3.041LeuTyr: 3.041 ± 0.396
0.0LeuXaa: 0.0 ± 0.0
Met
2.661MetAla: 2.661 ± 0.456
0.76MetCys: 0.76 ± 0.42
1.52MetAsp: 1.52 ± 0.444
2.281MetGlu: 2.281 ± 1.26
0.0MetPhe: 0.0 ± 0.0
2.661MetGly: 2.661 ± 0.186
0.0MetHis: 0.0 ± 0.0
0.76MetIle: 0.76 ± 0.42
2.661MetLys: 2.661 ± 0.186
1.52MetLeu: 1.52 ± 0.84
0.0MetMet: 0.0 ± 0.0
0.76MetAsn: 0.76 ± 0.222
3.041MetPro: 3.041 ± 0.246
0.76MetGln: 0.76 ± 0.42
2.281MetArg: 2.281 ± 0.618
3.421MetSer: 3.421 ± 1.248
0.76MetThr: 0.76 ± 0.222
1.9MetVal: 1.9 ± 0.408
0.76MetTrp: 0.76 ± 0.222
1.52MetTyr: 1.52 ± 0.198
0.0MetXaa: 0.0 ± 0.0
Asn
1.52AsnAla: 1.52 ± 0.198
0.76AsnCys: 0.76 ± 0.222
3.801AsnAsp: 3.801 ± 1.11
2.281AsnGlu: 2.281 ± 1.308
2.661AsnPhe: 2.661 ± 1.098
4.181AsnGly: 4.181 ± 1.542
0.76AsnHis: 0.76 ± 0.42
2.281AsnIle: 2.281 ± 0.618
1.9AsnLys: 1.9 ± 1.05
2.661AsnLeu: 2.661 ± 1.098
1.52AsnMet: 1.52 ± 1.086
2.281AsnAsn: 2.281 ± 0.666
4.561AsnPro: 4.561 ± 0.69
1.9AsnGln: 1.9 ± 0.408
1.9AsnArg: 1.9 ± 0.234
3.041AsnSer: 3.041 ± 1.038
3.041AsnThr: 3.041 ± 0.888
3.421AsnVal: 3.421 ± 0.678
0.76AsnTrp: 0.76 ± 0.42
2.281AsnTyr: 2.281 ± 0.666
0.0AsnXaa: 0.0 ± 0.0
Pro
4.561ProAla: 4.561 ± 1.332
0.76ProCys: 0.76 ± 0.864
2.661ProAsp: 2.661 ± 0.186
1.9ProGlu: 1.9 ± 0.234
1.9ProPhe: 1.9 ± 1.518
1.9ProGly: 1.9 ± 0.876
1.52ProHis: 1.52 ± 0.198
3.801ProIle: 3.801 ± 0.816
1.52ProLys: 1.52 ± 0.84
3.421ProLeu: 3.421 ± 1.248
1.52ProMet: 1.52 ± 0.198
2.661ProAsn: 2.661 ± 1.098
0.76ProPro: 0.76 ± 0.222
3.421ProGln: 3.421 ± 0.036
1.52ProArg: 1.52 ± 0.444
3.421ProSer: 3.421 ± 0.036
6.461ProThr: 6.461 ± 3.493
3.801ProVal: 3.801 ± 1.752
1.14ProTrp: 1.14 ± 0.012
1.52ProTyr: 1.52 ± 1.086
0.0ProXaa: 0.0 ± 0.0
Gln
2.661GlnAla: 2.661 ± 0.186
0.38GlnCys: 0.38 ± 0.21
0.38GlnAsp: 0.38 ± 0.21
1.9GlnGlu: 1.9 ± 0.234
3.041GlnPhe: 3.041 ± 0.396
3.801GlnGly: 3.801 ± 1.11
0.38GlnHis: 0.38 ± 0.432
1.9GlnIle: 1.9 ± 0.234
1.14GlnLys: 1.14 ± 0.012
3.041GlnLeu: 3.041 ± 0.246
2.281GlnMet: 2.281 ± 0.618
1.52GlnAsn: 1.52 ± 0.444
1.14GlnPro: 1.14 ± 0.654
1.52GlnGln: 1.52 ± 0.198
1.14GlnArg: 1.14 ± 0.63
3.421GlnSer: 3.421 ± 0.678
1.14GlnThr: 1.14 ± 0.012
4.181GlnVal: 4.181 ± 1.026
0.76GlnTrp: 0.76 ± 0.42
1.14GlnTyr: 1.14 ± 0.012
0.0GlnXaa: 0.0 ± 0.0
Arg
1.52ArgAla: 1.52 ± 1.086
0.0ArgCys: 0.0 ± 0.0
2.661ArgAsp: 2.661 ± 0.186
3.421ArgGlu: 3.421 ± 0.678
3.041ArgPhe: 3.041 ± 0.396
2.281ArgGly: 2.281 ± 0.024
0.76ArgHis: 0.76 ± 0.42
2.661ArgIle: 2.661 ± 0.186
3.041ArgLys: 3.041 ± 1.68
4.561ArgLeu: 4.561 ± 0.69
1.9ArgMet: 1.9 ± 1.05
2.281ArgAsn: 2.281 ± 0.666
2.281ArgPro: 2.281 ± 0.024
0.76ArgGln: 0.76 ± 0.42
1.14ArgArg: 1.14 ± 0.012
3.041ArgSer: 3.041 ± 0.396
2.281ArgThr: 2.281 ± 0.024
3.421ArgVal: 3.421 ± 0.036
0.76ArgTrp: 0.76 ± 0.864
1.52ArgTyr: 1.52 ± 0.444
0.0ArgXaa: 0.0 ± 0.0
Ser
4.941SerAla: 4.941 ± 1.765
0.76SerCys: 0.76 ± 0.42
3.041SerAsp: 3.041 ± 0.888
2.661SerGlu: 2.661 ± 0.828
3.421SerPhe: 3.421 ± 1.248
6.842SerGly: 6.842 ± 0.715
1.9SerHis: 1.9 ± 1.05
3.801SerIle: 3.801 ± 0.816
4.181SerLys: 4.181 ± 1.026
6.842SerLeu: 6.842 ± 0.072
3.041SerMet: 3.041 ± 0.396
3.421SerAsn: 3.421 ± 0.036
3.801SerPro: 3.801 ± 0.468
3.421SerGln: 3.421 ± 1.248
3.801SerArg: 3.801 ± 0.468
3.801SerSer: 3.801 ± 0.816
4.561SerThr: 4.561 ± 0.048
5.321SerVal: 5.321 ± 1.656
0.76SerTrp: 0.76 ± 0.222
1.9SerTyr: 1.9 ± 0.876
0.0SerXaa: 0.0 ± 0.0
Thr
4.181ThrAla: 4.181 ± 2.184
0.0ThrCys: 0.0 ± 0.0
4.181ThrAsp: 4.181 ± 1.542
2.281ThrGlu: 2.281 ± 1.26
3.421ThrPhe: 3.421 ± 0.036
3.801ThrGly: 3.801 ± 1.752
1.14ThrHis: 1.14 ± 0.63
2.661ThrIle: 2.661 ± 1.098
3.041ThrLys: 3.041 ± 0.246
6.842ThrLeu: 6.842 ± 0.715
2.661ThrMet: 2.661 ± 0.456
4.181ThrAsn: 4.181 ± 1.542
4.941ThrPro: 4.941 ± 1.765
1.52ThrGln: 1.52 ± 0.444
1.52ThrArg: 1.52 ± 0.444
4.941ThrSer: 4.941 ± 0.48
4.561ThrThr: 4.561 ± 1.974
6.842ThrVal: 6.842 ± 1.357
0.76ThrTrp: 0.76 ± 0.42
2.661ThrTyr: 2.661 ± 0.456
0.0ThrXaa: 0.0 ± 0.0
Val
5.321ValAla: 5.321 ± 1.656
1.9ValCys: 1.9 ± 1.05
3.421ValAsp: 3.421 ± 0.036
6.461ValGlu: 6.461 ± 1.002
1.9ValPhe: 1.9 ± 0.234
4.941ValGly: 4.941 ± 0.48
2.661ValHis: 2.661 ± 0.456
4.941ValIle: 4.941 ± 0.48
6.081ValLys: 6.081 ± 1.434
6.081ValLeu: 6.081 ± 0.792
2.281ValMet: 2.281 ± 1.26
2.281ValAsn: 2.281 ± 0.618
4.181ValPro: 4.181 ± 1.542
2.661ValGln: 2.661 ± 0.186
3.041ValArg: 3.041 ± 1.038
4.941ValSer: 4.941 ± 0.48
5.701ValThr: 5.701 ± 1.224
5.701ValVal: 5.701 ± 0.702
0.38ValTrp: 0.38 ± 0.21
2.661ValTyr: 2.661 ± 0.186
0.0ValXaa: 0.0 ± 0.0
Trp
1.14TrpAla: 1.14 ± 0.012
0.0TrpCys: 0.0 ± 0.0
0.76TrpAsp: 0.76 ± 0.864
1.9TrpGlu: 1.9 ± 1.05
1.14TrpPhe: 1.14 ± 0.012
0.76TrpGly: 0.76 ± 0.222
0.76TrpHis: 0.76 ± 0.222
0.38TrpIle: 0.38 ± 0.21
1.14TrpLys: 1.14 ± 0.63
0.38TrpLeu: 0.38 ± 0.21
0.0TrpMet: 0.0 ± 0.0
1.52TrpAsn: 1.52 ± 0.198
0.76TrpPro: 0.76 ± 0.864
0.76TrpGln: 0.76 ± 0.864
1.14TrpArg: 1.14 ± 0.654
0.38TrpSer: 0.38 ± 0.432
0.38TrpThr: 0.38 ± 0.21
1.52TrpVal: 1.52 ± 0.444
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.421TyrAla: 3.421 ± 0.036
0.38TyrCys: 0.38 ± 0.21
1.9TyrAsp: 1.9 ± 0.234
1.52TyrGlu: 1.52 ± 0.444
1.52TyrPhe: 1.52 ± 0.84
3.421TyrGly: 3.421 ± 0.606
0.76TyrHis: 0.76 ± 0.222
1.9TyrIle: 1.9 ± 1.05
0.76TyrLys: 0.76 ± 0.222
2.281TyrLeu: 2.281 ± 0.024
1.14TyrMet: 1.14 ± 0.012
2.281TyrAsn: 2.281 ± 1.95
1.52TyrPro: 1.52 ± 0.84
0.76TyrGln: 0.76 ± 0.42
1.9TyrArg: 1.9 ± 0.234
3.801TyrSer: 3.801 ± 1.11
2.661TyrThr: 2.661 ± 0.456
2.281TyrVal: 2.281 ± 0.024
0.38TyrTrp: 0.38 ± 0.21
0.76TyrTyr: 0.76 ± 0.222
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2632 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski