Amino acid dipepetide frequency for Leptonychotes weddellii polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.846AlaAla: 6.846 ± 2.613
0.489AlaCys: 0.489 ± 0.353
2.934AlaAsp: 2.934 ± 0.622
1.956AlaGlu: 1.956 ± 0.728
1.956AlaPhe: 1.956 ± 1.061
2.445AlaGly: 2.445 ± 0.79
0.978AlaHis: 0.978 ± 1.405
3.423AlaIle: 3.423 ± 1.474
2.445AlaLys: 2.445 ± 1.277
6.846AlaLeu: 6.846 ± 2.671
0.489AlaMet: 0.489 ± 0.353
1.956AlaAsn: 1.956 ± 2.26
4.89AlaPro: 4.89 ± 1.211
2.445AlaGln: 2.445 ± 0.685
3.912AlaArg: 3.912 ± 1.042
5.868AlaSer: 5.868 ± 3.397
2.445AlaThr: 2.445 ± 1.13
2.934AlaVal: 2.934 ± 0.816
0.489AlaTrp: 0.489 ± 0.353
1.467AlaTyr: 1.467 ± 1.155
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.978CysCys: 0.978 ± 0.424
0.489CysAsp: 0.489 ± 0.464
0.489CysGlu: 0.489 ± 0.353
0.489CysPhe: 0.489 ± 0.568
0.0CysGly: 0.0 ± 0.0
0.489CysHis: 0.489 ± 1.114
0.489CysIle: 0.489 ± 0.692
2.445CysLys: 2.445 ± 1.238
2.445CysLeu: 2.445 ± 1.375
0.978CysMet: 0.978 ± 0.705
0.978CysAsn: 0.978 ± 0.424
0.489CysPro: 0.489 ± 0.568
0.489CysGln: 0.489 ± 0.353
1.467CysArg: 1.467 ± 1.058
0.489CysSer: 0.489 ± 0.353
0.489CysThr: 0.489 ± 0.353
1.467CysVal: 1.467 ± 1.097
0.978CysTrp: 0.978 ± 0.696
1.956CysTyr: 1.956 ± 1.719
0.0CysXaa: 0.0 ± 0.0
Asp
1.467AspAla: 1.467 ± 0.817
0.0AspCys: 0.0 ± 0.0
3.423AspAsp: 3.423 ± 1.17
4.89AspGlu: 4.89 ± 1.202
1.956AspPhe: 1.956 ± 0.672
1.956AspGly: 1.956 ± 0.543
0.978AspHis: 0.978 ± 0.705
3.423AspIle: 3.423 ± 1.011
6.846AspLys: 6.846 ± 1.46
8.313AspLeu: 8.313 ± 1.744
0.978AspMet: 0.978 ± 0.587
1.956AspAsn: 1.956 ± 0.881
3.423AspPro: 3.423 ± 1.469
0.978AspGln: 0.978 ± 0.705
0.978AspArg: 0.978 ± 0.584
1.956AspSer: 1.956 ± 0.881
3.912AspThr: 3.912 ± 1.91
6.846AspVal: 6.846 ± 2.361
2.934AspTrp: 2.934 ± 1.421
1.467AspTyr: 1.467 ± 0.71
0.0AspXaa: 0.0 ± 0.0
Glu
2.445GluAla: 2.445 ± 1.421
0.489GluCys: 0.489 ± 0.464
10.758GluAsp: 10.758 ± 2.07
9.291GluGlu: 9.291 ± 2.961
1.467GluPhe: 1.467 ± 0.586
2.445GluGly: 2.445 ± 0.875
1.467GluHis: 1.467 ± 1.082
2.934GluIle: 2.934 ± 1.359
5.379GluLys: 5.379 ± 2.026
8.313GluLeu: 8.313 ± 3.048
0.978GluMet: 0.978 ± 0.677
4.401GluAsn: 4.401 ± 1.236
2.445GluPro: 2.445 ± 1.216
0.0GluGln: 0.0 ± 0.0
2.445GluArg: 2.445 ± 0.685
5.379GluSer: 5.379 ± 1.504
3.912GluThr: 3.912 ± 0.76
4.89GluVal: 4.89 ± 1.433
0.0GluTrp: 0.0 ± 0.0
1.467GluTyr: 1.467 ± 0.781
0.0GluXaa: 0.0 ± 0.0
Phe
1.467PheAla: 1.467 ± 0.71
0.978PheCys: 0.978 ± 0.705
1.956PheAsp: 1.956 ± 1.169
3.912PheGlu: 3.912 ± 1.347
1.467PhePhe: 1.467 ± 0.694
3.423PheGly: 3.423 ± 1.106
0.489PheHis: 0.489 ± 0.353
2.934PheIle: 2.934 ± 0.421
1.467PheLys: 1.467 ± 0.627
2.934PheLeu: 2.934 ± 1.019
0.978PheMet: 0.978 ± 1.286
1.467PheAsn: 1.467 ± 0.627
2.445PhePro: 2.445 ± 0.558
1.467PheGln: 1.467 ± 0.627
1.467PheArg: 1.467 ± 0.817
2.445PheSer: 2.445 ± 1.13
0.978PheThr: 0.978 ± 0.557
1.467PheVal: 1.467 ± 0.781
0.978PheTrp: 0.978 ± 0.745
1.467PheTyr: 1.467 ± 1.097
0.0PheXaa: 0.0 ± 0.0
Gly
6.357GlyAla: 6.357 ± 1.592
0.489GlyCys: 0.489 ± 0.353
7.824GlyAsp: 7.824 ± 1.012
4.401GlyGlu: 4.401 ± 2.22
2.445GlyPhe: 2.445 ± 0.536
8.313GlyGly: 8.313 ± 1.482
2.934GlyHis: 2.934 ± 0.622
4.401GlyIle: 4.401 ± 0.992
2.445GlyLys: 2.445 ± 0.852
3.423GlyLeu: 3.423 ± 0.6
2.445GlyMet: 2.445 ± 0.869
1.467GlyAsn: 1.467 ± 0.869
6.846GlyPro: 6.846 ± 3.121
1.467GlyGln: 1.467 ± 0.694
1.467GlyArg: 1.467 ± 0.828
2.934GlySer: 2.934 ± 0.8
4.89GlyThr: 4.89 ± 2.194
5.868GlyVal: 5.868 ± 1.051
0.0GlyTrp: 0.0 ± 0.0
0.978GlyTyr: 0.978 ± 0.928
0.0GlyXaa: 0.0 ± 0.0
His
2.934HisAla: 2.934 ± 1.387
1.956HisCys: 1.956 ± 1.426
0.0HisAsp: 0.0 ± 0.0
1.467HisGlu: 1.467 ± 0.627
0.978HisPhe: 0.978 ± 0.424
0.978HisGly: 0.978 ± 0.928
0.489HisHis: 0.489 ± 0.692
0.0HisIle: 0.0 ± 0.0
1.956HisLys: 1.956 ± 1.861
2.934HisLeu: 2.934 ± 1.435
0.489HisMet: 0.489 ± 0.568
0.0HisAsn: 0.0 ± 0.0
1.956HisPro: 1.956 ± 1.256
0.978HisGln: 0.978 ± 0.702
1.467HisArg: 1.467 ± 0.781
1.956HisSer: 1.956 ± 1.45
0.489HisThr: 0.489 ± 1.114
1.956HisVal: 1.956 ± 1.489
0.489HisTrp: 0.489 ± 0.692
1.956HisTyr: 1.956 ± 0.839
0.0HisXaa: 0.0 ± 0.0
Ile
2.445IleAla: 2.445 ± 2.493
0.489IleCys: 0.489 ± 0.353
2.934IleAsp: 2.934 ± 0.774
5.868IleGlu: 5.868 ± 1.025
0.489IlePhe: 0.489 ± 0.568
3.423IleGly: 3.423 ± 1.207
0.0IleHis: 0.0 ± 0.0
1.467IleIle: 1.467 ± 0.781
3.423IleLys: 3.423 ± 1.316
6.357IleLeu: 6.357 ± 1.787
0.978IleMet: 0.978 ± 0.424
1.956IleAsn: 1.956 ± 0.93
2.934IlePro: 2.934 ± 1.172
1.467IleGln: 1.467 ± 0.71
0.489IleArg: 0.489 ± 0.353
4.401IleSer: 4.401 ± 2.133
1.956IleThr: 1.956 ± 0.715
2.934IleVal: 2.934 ± 1.0
0.0IleTrp: 0.0 ± 0.0
1.956IleTyr: 1.956 ± 0.925
0.0IleXaa: 0.0 ± 0.0
Lys
2.934LysAla: 2.934 ± 1.714
1.467LysCys: 1.467 ± 1.097
0.978LysAsp: 0.978 ± 0.424
6.846LysGlu: 6.846 ± 2.338
2.934LysPhe: 2.934 ± 1.589
4.89LysGly: 4.89 ± 1.7
2.445LysHis: 2.445 ± 0.899
5.868LysIle: 5.868 ± 2.395
7.335LysLys: 7.335 ± 2.79
3.912LysLeu: 3.912 ± 1.486
0.489LysMet: 0.489 ± 0.353
1.956LysAsn: 1.956 ± 0.881
1.467LysPro: 1.467 ± 1.083
1.956LysGln: 1.956 ± 0.839
7.824LysArg: 7.824 ± 0.719
2.934LysSer: 2.934 ± 1.189
2.445LysThr: 2.445 ± 0.899
1.956LysVal: 1.956 ± 1.309
0.489LysTrp: 0.489 ± 1.114
2.445LysTyr: 2.445 ± 0.685
0.0LysXaa: 0.0 ± 0.0
Leu
5.868LeuAla: 5.868 ± 2.015
1.956LeuCys: 1.956 ± 0.881
7.335LeuAsp: 7.335 ± 1.012
5.868LeuGlu: 5.868 ± 0.739
6.846LeuPhe: 6.846 ± 1.532
6.357LeuGly: 6.357 ± 1.451
1.467LeuHis: 1.467 ± 1.058
1.467LeuIle: 1.467 ± 0.441
1.956LeuLys: 1.956 ± 1.256
13.692LeuLeu: 13.692 ± 3.335
2.934LeuMet: 2.934 ± 0.901
5.868LeuAsn: 5.868 ± 1.182
7.824LeuPro: 7.824 ± 0.886
5.379LeuGln: 5.379 ± 1.211
2.934LeuArg: 2.934 ± 0.774
4.89LeuSer: 4.89 ± 1.854
7.824LeuThr: 7.824 ± 1.594
2.934LeuVal: 2.934 ± 0.82
1.467LeuTrp: 1.467 ± 1.097
3.912LeuTyr: 3.912 ± 1.548
0.0LeuXaa: 0.0 ± 0.0
Met
1.956MetAla: 1.956 ± 0.839
0.978MetCys: 0.978 ± 0.584
0.978MetAsp: 0.978 ± 0.584
1.467MetGlu: 1.467 ± 0.681
0.0MetPhe: 0.0 ± 0.0
1.467MetGly: 1.467 ± 0.754
0.0MetHis: 0.0 ± 0.0
0.489MetIle: 0.489 ± 0.568
1.956MetLys: 1.956 ± 0.849
0.978MetLeu: 0.978 ± 0.928
0.489MetMet: 0.489 ± 0.692
0.0MetAsn: 0.0 ± 0.0
0.978MetPro: 0.978 ± 0.702
1.467MetGln: 1.467 ± 1.393
1.956MetArg: 1.956 ± 1.516
1.956MetSer: 1.956 ± 1.073
1.956MetThr: 1.956 ± 0.881
0.489MetVal: 0.489 ± 0.353
1.467MetTrp: 1.467 ± 0.586
0.978MetTyr: 0.978 ± 1.121
0.0MetXaa: 0.0 ± 0.0
Asn
1.467AsnAla: 1.467 ± 0.627
0.978AsnCys: 0.978 ± 0.584
1.467AsnAsp: 1.467 ± 0.627
2.445AsnGlu: 2.445 ± 1.216
1.956AsnPhe: 1.956 ± 0.728
1.467AsnGly: 1.467 ± 0.681
1.956AsnHis: 1.956 ± 0.728
1.956AsnIle: 1.956 ± 1.411
3.423AsnLys: 3.423 ± 0.691
1.467AsnLeu: 1.467 ± 0.627
0.489AsnMet: 0.489 ± 0.353
0.978AsnAsn: 0.978 ± 1.148
2.445AsnPro: 2.445 ± 0.685
0.978AsnGln: 0.978 ± 0.696
3.423AsnArg: 3.423 ± 1.67
2.445AsnSer: 2.445 ± 0.899
1.956AsnThr: 1.956 ± 0.747
2.934AsnVal: 2.934 ± 1.309
0.0AsnTrp: 0.0 ± 0.0
1.467AsnTyr: 1.467 ± 1.038
0.0AsnXaa: 0.0 ± 0.0
Pro
3.912ProAla: 3.912 ± 2.509
0.978ProCys: 0.978 ± 0.696
6.357ProAsp: 6.357 ± 1.769
1.467ProGlu: 1.467 ± 0.627
0.489ProPhe: 0.489 ± 0.353
3.912ProGly: 3.912 ± 1.312
0.0ProHis: 0.0 ± 0.0
0.978ProIle: 0.978 ± 1.148
3.423ProLys: 3.423 ± 1.066
7.824ProLeu: 7.824 ± 2.147
2.445ProMet: 2.445 ± 1.281
1.956ProAsn: 1.956 ± 0.747
7.824ProPro: 7.824 ± 2.652
2.934ProGln: 2.934 ± 1.533
1.956ProArg: 1.956 ± 1.259
7.824ProSer: 7.824 ± 2.2
2.445ProThr: 2.445 ± 2.181
4.401ProVal: 4.401 ± 1.962
0.0ProTrp: 0.0 ± 0.0
1.467ProTyr: 1.467 ± 0.817
0.0ProXaa: 0.0 ± 0.0
Gln
1.467GlnAla: 1.467 ± 1.046
0.0GlnCys: 0.0 ± 0.0
0.489GlnAsp: 0.489 ± 0.353
3.912GlnGlu: 3.912 ± 0.89
0.978GlnPhe: 0.978 ± 0.424
1.467GlnGly: 1.467 ± 0.627
0.978GlnHis: 0.978 ± 0.705
2.934GlnIle: 2.934 ± 1.387
2.445GlnLys: 2.445 ± 0.558
2.934GlnLeu: 2.934 ± 1.048
0.489GlnMet: 0.489 ± 0.692
1.467GlnAsn: 1.467 ± 0.627
1.467GlnPro: 1.467 ± 1.393
1.467GlnGln: 1.467 ± 0.627
4.401GlnArg: 4.401 ± 2.053
1.956GlnSer: 1.956 ± 0.839
1.467GlnThr: 1.467 ± 0.694
4.401GlnVal: 4.401 ± 1.579
0.489GlnTrp: 0.489 ± 0.353
1.956GlnTyr: 1.956 ± 0.916
0.0GlnXaa: 0.0 ± 0.0
Arg
2.934ArgAla: 2.934 ± 1.031
0.978ArgCys: 0.978 ± 0.584
2.445ArgAsp: 2.445 ± 0.79
1.467ArgGlu: 1.467 ± 0.71
3.423ArgPhe: 3.423 ± 1.464
2.445ArgGly: 2.445 ± 1.052
3.423ArgHis: 3.423 ± 1.558
2.934ArgIle: 2.934 ± 0.774
6.357ArgLys: 6.357 ± 1.451
3.423ArgLeu: 3.423 ± 0.975
0.978ArgMet: 0.978 ± 0.663
1.956ArgAsn: 1.956 ± 1.208
2.445ArgPro: 2.445 ± 1.264
2.445ArgGln: 2.445 ± 1.276
10.758ArgArg: 10.758 ± 6.181
4.401ArgSer: 4.401 ± 0.676
2.934ArgThr: 2.934 ± 1.217
2.934ArgVal: 2.934 ± 1.217
0.978ArgTrp: 0.978 ± 0.745
4.401ArgTyr: 4.401 ± 1.125
0.0ArgXaa: 0.0 ± 0.0
Ser
4.89SerAla: 4.89 ± 1.579
1.467SerCys: 1.467 ± 0.817
0.978SerAsp: 0.978 ± 0.705
2.934SerGlu: 2.934 ± 1.551
3.912SerPhe: 3.912 ± 1.122
5.868SerGly: 5.868 ± 1.465
1.467SerHis: 1.467 ± 1.261
3.423SerIle: 3.423 ± 2.136
3.912SerLys: 3.912 ± 1.629
7.824SerLeu: 7.824 ± 2.533
0.978SerMet: 0.978 ± 0.873
3.423SerAsn: 3.423 ± 0.6
1.467SerPro: 1.467 ± 0.905
3.912SerGln: 3.912 ± 0.926
5.379SerArg: 5.379 ± 2.017
2.934SerSer: 2.934 ± 2.618
2.445SerThr: 2.445 ± 1.252
6.357SerVal: 6.357 ± 1.568
1.467SerTrp: 1.467 ± 0.781
0.978SerTyr: 0.978 ± 0.557
0.0SerXaa: 0.0 ± 0.0
Thr
0.978ThrAla: 0.978 ± 1.148
1.956ThrCys: 1.956 ± 1.355
1.467ThrAsp: 1.467 ± 0.905
4.89ThrGlu: 4.89 ± 2.586
1.467ThrPhe: 1.467 ± 0.817
5.868ThrGly: 5.868 ± 2.025
1.467ThrHis: 1.467 ± 0.681
1.467ThrIle: 1.467 ± 1.393
0.489ThrLys: 0.489 ± 0.568
4.401ThrLeu: 4.401 ± 1.734
0.489ThrMet: 0.489 ± 0.501
0.978ThrAsn: 0.978 ± 0.424
3.912ThrPro: 3.912 ± 1.311
3.912ThrGln: 3.912 ± 1.386
3.423ThrArg: 3.423 ± 2.121
2.445ThrSer: 2.445 ± 0.558
2.445ThrThr: 2.445 ± 1.122
3.912ThrVal: 3.912 ± 1.463
2.445ThrTrp: 2.445 ± 2.391
1.467ThrTyr: 1.467 ± 0.627
0.0ThrXaa: 0.0 ± 0.0
Val
3.423ValAla: 3.423 ± 1.564
0.489ValCys: 0.489 ± 0.353
3.912ValAsp: 3.912 ± 0.926
4.401ValGlu: 4.401 ± 1.236
1.956ValPhe: 1.956 ± 0.839
6.357ValGly: 6.357 ± 3.562
1.467ValHis: 1.467 ± 1.082
3.912ValIle: 3.912 ± 1.088
3.423ValLys: 3.423 ± 1.18
4.401ValLeu: 4.401 ± 0.937
2.934ValMet: 2.934 ± 0.971
1.467ValAsn: 1.467 ± 0.781
4.401ValPro: 4.401 ± 1.534
1.956ValGln: 1.956 ± 0.521
3.912ValArg: 3.912 ± 1.121
5.868ValSer: 5.868 ± 2.071
3.912ValThr: 3.912 ± 0.926
1.956ValVal: 1.956 ± 0.881
1.956ValTrp: 1.956 ± 1.208
0.978ValTyr: 0.978 ± 0.424
0.0ValXaa: 0.0 ± 0.0
Trp
0.978TrpAla: 0.978 ± 0.745
0.0TrpCys: 0.0 ± 0.0
0.978TrpAsp: 0.978 ± 0.705
0.489TrpGlu: 0.489 ± 0.464
0.489TrpPhe: 0.489 ± 0.568
3.423TrpGly: 3.423 ± 1.548
0.978TrpHis: 0.978 ± 1.148
0.978TrpIle: 0.978 ± 0.966
0.978TrpLys: 0.978 ± 1.121
1.467TrpLeu: 1.467 ± 0.71
0.0TrpMet: 0.0 ± 0.0
0.489TrpAsn: 0.489 ± 0.568
0.489TrpPro: 0.489 ± 1.114
0.978TrpGln: 0.978 ± 0.745
2.445TrpArg: 2.445 ± 1.095
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
1.467TrpVal: 1.467 ± 0.71
0.489TrpTrp: 0.489 ± 0.353
0.978TrpTyr: 0.978 ± 0.745
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.445TyrAla: 2.445 ± 1.03
0.978TyrCys: 0.978 ± 1.136
0.978TyrAsp: 0.978 ± 0.705
2.445TyrGlu: 2.445 ± 1.011
0.978TyrPhe: 0.978 ± 0.928
4.89TyrGly: 4.89 ± 1.993
1.956TyrHis: 1.956 ± 0.672
0.489TyrIle: 0.489 ± 0.464
1.467TyrLys: 1.467 ± 0.817
4.89TyrLeu: 4.89 ± 2.146
0.489TyrMet: 0.489 ± 0.568
0.978TyrAsn: 0.978 ± 0.705
2.445TyrPro: 2.445 ± 1.276
0.489TyrGln: 0.489 ± 0.464
1.956TyrArg: 1.956 ± 1.169
2.934TyrSer: 2.934 ± 0.89
0.978TyrThr: 0.978 ± 0.696
0.978TyrVal: 0.978 ± 0.587
0.978TyrTrp: 0.978 ± 0.745
1.467TyrTyr: 1.467 ± 0.71
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2046 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski