Amino acid dipepetide frequency for Aurantiacibacter marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.445AlaAla: 16.445 ± 0.205	1.09AlaCys: 1.09 ± 0.038	7.342AlaAsp: 7.342 ± 0.077	8.17AlaGlu: 8.17 ± 0.117	4.334AlaPhe: 4.334 ± 0.079	10.785AlaGly: 10.785 ± 0.136	2.179AlaHis: 2.179 ± 0.059	6.881AlaIle: 6.881 ± 0.104	3.865AlaLys: 3.865 ± 0.096	12.742AlaLeu: 12.742 ± 0.175	4.066AlaMet: 4.066 ± 0.079	3.448AlaAsn: 3.448 ± 0.075	5.333AlaPro: 5.333 ± 0.114	4.77AlaGln: 4.77 ± 0.08	8.378AlaArg: 8.378 ± 0.112	6.415AlaSer: 6.415 ± 0.11	5.62AlaThr: 5.62 ± 0.081	8.04AlaVal: 8.04 ± 0.116	1.406AlaTrp: 1.406 ± 0.046	2.504AlaTyr: 2.504 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	1.0CysAla: 1.0 ± 0.035	0.095CysCys: 0.095 ± 0.011	0.626CysAsp: 0.626 ± 0.029	0.504CysGlu: 0.504 ± 0.025	0.283CysPhe: 0.283 ± 0.021	0.892CysGly: 0.892 ± 0.036	0.233CysHis: 0.233 ± 0.022	0.43CysIle: 0.43 ± 0.022	0.191CysLys: 0.191 ± 0.015	0.632CysLeu: 0.632 ± 0.028	0.168CysMet: 0.168 ± 0.014	0.276CysAsn: 0.276 ± 0.017	0.461CysPro: 0.461 ± 0.025	0.229CysGln: 0.229 ± 0.017	0.516CysArg: 0.516 ± 0.027	0.476CysSer: 0.476 ± 0.024	0.433CysThr: 0.433 ± 0.024	0.585CysVal: 0.585 ± 0.026	0.119CysTrp: 0.119 ± 0.012	0.176CysTyr: 0.176 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	7.592AspAla: 7.592 ± 0.105	0.572AspCys: 0.572 ± 0.028	3.788AspAsp: 3.788 ± 0.092	4.023AspGlu: 4.023 ± 0.085	2.456AspPhe: 2.456 ± 0.059	5.884AspGly: 5.884 ± 0.085	1.322AspHis: 1.322 ± 0.05	3.284AspIle: 3.284 ± 0.068	1.663AspLys: 1.663 ± 0.056	5.986AspLeu: 5.986 ± 0.083	1.683AspMet: 1.683 ± 0.049	1.765AspAsn: 1.765 ± 0.053	3.75AspPro: 3.75 ± 0.078	1.825AspGln: 1.825 ± 0.048	4.442AspArg: 4.442 ± 0.088	2.565AspSer: 2.565 ± 0.056	3.102AspThr: 3.102 ± 0.061	4.046AspVal: 4.046 ± 0.069	1.186AspTrp: 1.186 ± 0.036	1.558AspTyr: 1.558 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	7.885GluAla: 7.885 ± 0.116	0.403GluCys: 0.403 ± 0.025	3.727GluAsp: 3.727 ± 0.067	4.137GluGlu: 4.137 ± 0.095	2.03GluPhe: 2.03 ± 0.05	5.203GluGly: 5.203 ± 0.084	1.247GluHis: 1.247 ± 0.042	3.354GluIle: 3.354 ± 0.061	2.245GluLys: 2.245 ± 0.063	5.717GluLeu: 5.717 ± 0.089	1.878GluMet: 1.878 ± 0.051	1.893GluAsn: 1.893 ± 0.049	2.769GluPro: 2.769 ± 0.06	2.409GluGln: 2.409 ± 0.055	4.908GluArg: 4.908 ± 0.084	2.871GluSer: 2.871 ± 0.061	3.49GluThr: 3.49 ± 0.066	4.064GluVal: 4.064 ± 0.08	0.982GluTrp: 0.982 ± 0.037	1.29GluTyr: 1.29 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	5.161PheAla: 5.161 ± 0.091	0.342PheCys: 0.342 ± 0.022	2.901PheAsp: 2.901 ± 0.062	2.271PheGlu: 2.271 ± 0.05	1.446PhePhe: 1.446 ± 0.045	3.856PheGly: 3.856 ± 0.079	0.721PheHis: 0.721 ± 0.031	1.747PheIle: 1.747 ± 0.047	0.811PheLys: 0.811 ± 0.038	3.19PheLeu: 3.19 ± 0.071	0.857PheMet: 0.857 ± 0.032	1.133PheAsn: 1.133 ± 0.046	1.598PhePro: 1.598 ± 0.049	0.946PheGln: 0.946 ± 0.035	2.144PheArg: 2.144 ± 0.056	2.276PheSer: 2.276 ± 0.052	2.251PheThr: 2.251 ± 0.058	2.764PheVal: 2.764 ± 0.061	0.592PheTrp: 0.592 ± 0.03	0.998PheTyr: 0.998 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	9.417GlyAla: 9.417 ± 0.127	0.883GlyCys: 0.883 ± 0.028	5.236GlyAsp: 5.236 ± 0.082	5.8GlyGlu: 5.8 ± 0.079	3.817GlyPhe: 3.817 ± 0.066	8.295GlyGly: 8.295 ± 0.171	1.794GlyHis: 1.794 ± 0.047	4.682GlyIle: 4.682 ± 0.079	3.212GlyLys: 3.212 ± 0.083	8.446GlyLeu: 8.446 ± 0.123	2.599GlyMet: 2.599 ± 0.058	2.705GlyAsn: 2.705 ± 0.065	3.595GlyPro: 3.595 ± 0.069	3.019GlyGln: 3.019 ± 0.065	5.827GlyArg: 5.827 ± 0.097	5.053GlySer: 5.053 ± 0.104	4.883GlyThr: 4.883 ± 0.106	6.064GlyVal: 6.064 ± 0.097	1.641GlyTrp: 1.641 ± 0.05	2.248GlyTyr: 2.248 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.166HisAla: 2.166 ± 0.059	0.256HisCys: 0.256 ± 0.02	1.22HisAsp: 1.22 ± 0.04	1.11HisGlu: 1.11 ± 0.037	0.901HisPhe: 0.901 ± 0.034	1.838HisGly: 1.838 ± 0.056	0.555HisHis: 0.555 ± 0.029	0.993HisIle: 0.993 ± 0.039	0.483HisLys: 0.483 ± 0.025	1.815HisLeu: 1.815 ± 0.052	0.437HisMet: 0.437 ± 0.021	0.533HisAsn: 0.533 ± 0.028	1.203HisPro: 1.203 ± 0.041	0.528HisGln: 0.528 ± 0.027	1.327HisArg: 1.327 ± 0.041	0.993HisSer: 0.993 ± 0.037	0.852HisThr: 0.852 ± 0.032	1.346HisVal: 1.346 ± 0.041	0.314HisTrp: 0.314 ± 0.023	0.565HisTyr: 0.565 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	7.967IleAla: 7.967 ± 0.107	0.483IleCys: 0.483 ± 0.023	3.68IleAsp: 3.68 ± 0.074	3.715IleGlu: 3.715 ± 0.063	1.833IlePhe: 1.833 ± 0.055	5.412IleGly: 5.412 ± 0.085	0.887IleHis: 0.887 ± 0.036	2.396IleIle: 2.396 ± 0.06	1.214IleLys: 1.214 ± 0.046	4.018IleLeu: 4.018 ± 0.077	1.1IleMet: 1.1 ± 0.04	1.481IleAsn: 1.481 ± 0.048	2.453IlePro: 2.453 ± 0.058	1.146IleGln: 1.146 ± 0.039	3.077IleArg: 3.077 ± 0.061	2.917IleSer: 2.917 ± 0.06	3.005IleThr: 3.005 ± 0.062	3.983IleVal: 3.983 ± 0.079	0.662IleTrp: 0.662 ± 0.03	1.056IleTyr: 1.056 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.586LysAla: 3.586 ± 0.091	0.157LysCys: 0.157 ± 0.014	1.531LysAsp: 1.531 ± 0.059	1.357LysGlu: 1.357 ± 0.049	0.91LysPhe: 0.91 ± 0.03	2.514LysGly: 2.514 ± 0.062	0.597LysHis: 0.597 ± 0.028	1.46LysIle: 1.46 ± 0.046	1.219LysLys: 1.219 ± 0.055	3.153LysLeu: 3.153 ± 0.073	0.8LysMet: 0.8 ± 0.034	0.761LysAsn: 0.761 ± 0.035	1.702LysPro: 1.702 ± 0.056	0.904LysGln: 0.904 ± 0.033	2.152LysArg: 2.152 ± 0.065	1.606LysSer: 1.606 ± 0.045	1.577LysThr: 1.577 ± 0.055	2.048LysVal: 2.048 ± 0.05	0.392LysTrp: 0.392 ± 0.021	0.588LysTyr: 0.588 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	13.319LeuAla: 13.319 ± 0.158	0.784LeuCys: 0.784 ± 0.033	6.019LeuAsp: 6.019 ± 0.091	5.77LeuGlu: 5.77 ± 0.094	3.658LeuPhe: 3.658 ± 0.073	8.204LeuGly: 8.204 ± 0.103	1.67LeuHis: 1.67 ± 0.047	4.765LeuIle: 4.765 ± 0.082	2.642LeuLys: 2.642 ± 0.074	9.411LeuLeu: 9.411 ± 0.147	2.158LeuMet: 2.158 ± 0.055	2.405LeuAsn: 2.405 ± 0.055	5.454LeuPro: 5.454 ± 0.077	2.753LeuGln: 2.753 ± 0.063	6.366LeuArg: 6.366 ± 0.107	5.993LeuSer: 5.993 ± 0.093	5.334LeuThr: 5.334 ± 0.076	7.098LeuVal: 7.098 ± 0.105	1.18LeuTrp: 1.18 ± 0.05	1.902LeuTyr: 1.902 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	3.459MetAla: 3.459 ± 0.08	0.177MetCys: 0.177 ± 0.014	1.428MetAsp: 1.428 ± 0.041	1.42MetGlu: 1.42 ± 0.044	0.801MetPhe: 0.801 ± 0.035	2.116MetGly: 2.116 ± 0.056	0.495MetHis: 0.495 ± 0.023	1.494MetIle: 1.494 ± 0.049	0.958MetLys: 0.958 ± 0.035	2.864MetLeu: 2.864 ± 0.077	0.703MetMet: 0.703 ± 0.031	0.79MetAsn: 0.79 ± 0.032	1.545MetPro: 1.545 ± 0.044	0.904MetGln: 0.904 ± 0.033	1.911MetArg: 1.911 ± 0.049	1.479MetSer: 1.479 ± 0.039	1.687MetThr: 1.687 ± 0.043	1.759MetVal: 1.759 ± 0.047	0.256MetTrp: 0.256 ± 0.021	0.334MetTyr: 0.334 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.512AsnAla: 3.512 ± 0.072	0.297AsnCys: 0.297 ± 0.023	1.594AsnAsp: 1.594 ± 0.045	1.368AsnGlu: 1.368 ± 0.04	1.108AsnPhe: 1.108 ± 0.041	2.565AsnGly: 2.565 ± 0.072	0.543AsnHis: 0.543 ± 0.026	1.471AsnIle: 1.471 ± 0.05	0.652AsnLys: 0.652 ± 0.031	2.672AsnLeu: 2.672 ± 0.07	0.687AsnMet: 0.687 ± 0.027	0.767AsnAsn: 0.767 ± 0.034	1.936AsnPro: 1.936 ± 0.052	0.806AsnGln: 0.806 ± 0.036	1.968AsnArg: 1.968 ± 0.055	1.553AsnSer: 1.553 ± 0.046	1.397AsnThr: 1.397 ± 0.048	2.094AsnVal: 2.094 ± 0.061	0.477AsnTrp: 0.477 ± 0.024	0.736AsnTyr: 0.736 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	6.139ProAla: 6.139 ± 0.103	0.297ProCys: 0.297 ± 0.022	3.887ProAsp: 3.887 ± 0.086	4.069ProGlu: 4.069 ± 0.075	1.984ProPhe: 1.984 ± 0.049	4.497ProGly: 4.497 ± 0.075	1.0ProHis: 1.0 ± 0.037	2.447ProIle: 2.447 ± 0.059	1.396ProLys: 1.396 ± 0.044	4.668ProLeu: 4.668 ± 0.076	1.155ProMet: 1.155 ± 0.039	1.271ProAsn: 1.271 ± 0.039	2.53ProPro: 2.53 ± 0.09	1.826ProGln: 1.826 ± 0.049	2.687ProArg: 2.687 ± 0.06	2.654ProSer: 2.654 ± 0.06	2.286ProThr: 2.286 ± 0.058	4.047ProVal: 4.047 ± 0.073	0.636ProTrp: 0.636 ± 0.03	1.093ProTyr: 1.093 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	4.024GlnAla: 4.024 ± 0.073	0.244GlnCys: 0.244 ± 0.017	1.745GlnAsp: 1.745 ± 0.051	1.702GlnGlu: 1.702 ± 0.051	1.231GlnPhe: 1.231 ± 0.041	2.526GlnGly: 2.526 ± 0.057	0.652GlnHis: 0.652 ± 0.032	1.957GlnIle: 1.957 ± 0.049	0.88GlnLys: 0.88 ± 0.036	3.33GlnLeu: 3.33 ± 0.068	0.953GlnMet: 0.953 ± 0.037	0.897GlnAsn: 0.897 ± 0.034	1.742GlnPro: 1.742 ± 0.047	1.314GlnGln: 1.314 ± 0.039	2.379GlnArg: 2.379 ± 0.063	1.904GlnSer: 1.904 ± 0.056	1.674GlnThr: 1.674 ± 0.049	2.367GlnVal: 2.367 ± 0.055	0.416GlnTrp: 0.416 ± 0.026	0.738GlnTyr: 0.738 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	7.318ArgAla: 7.318 ± 0.121	0.447ArgCys: 0.447 ± 0.024	4.313ArgAsp: 4.313 ± 0.081	4.521ArgGlu: 4.521 ± 0.087	2.972ArgPhe: 2.972 ± 0.058	4.861ArgGly: 4.861 ± 0.085	1.412ArgHis: 1.412 ± 0.041	3.91ArgIle: 3.91 ± 0.072	2.168ArgLys: 2.168 ± 0.055	6.987ArgLeu: 6.987 ± 0.114	1.97ArgMet: 1.97 ± 0.052	1.997ArgAsn: 1.997 ± 0.054	3.056ArgPro: 3.056 ± 0.069	2.433ArgGln: 2.433 ± 0.057	4.747ArgArg: 4.747 ± 0.094	3.648ArgSer: 3.648 ± 0.08	3.183ArgThr: 3.183 ± 0.059	4.425ArgVal: 4.425 ± 0.077	1.01ArgTrp: 1.01 ± 0.038	1.624ArgTyr: 1.624 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.516SerAla: 6.516 ± 0.111	0.458SerCys: 0.458 ± 0.025	3.546SerAsp: 3.546 ± 0.071	3.271SerGlu: 3.271 ± 0.07	2.265SerPhe: 2.265 ± 0.068	5.839SerGly: 5.839 ± 0.108	1.023SerHis: 1.023 ± 0.032	2.707SerIle: 2.707 ± 0.055	1.396SerLys: 1.396 ± 0.05	5.129SerLeu: 5.129 ± 0.086	1.352SerMet: 1.352 ± 0.039	1.571SerAsn: 1.571 ± 0.042	2.869SerPro: 2.869 ± 0.066	1.718SerGln: 1.718 ± 0.048	3.528SerArg: 3.528 ± 0.062	3.035SerSer: 3.035 ± 0.082	2.71SerThr: 2.71 ± 0.067	3.618SerVal: 3.618 ± 0.068	0.823SerTrp: 0.823 ± 0.026	1.328SerTyr: 1.328 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.996ThrAla: 5.996 ± 0.083	0.399ThrCys: 0.399 ± 0.023	3.142ThrAsp: 3.142 ± 0.066	2.701ThrGlu: 2.701 ± 0.061	1.942ThrPhe: 1.942 ± 0.058	5.488ThrGly: 5.488 ± 0.098	0.975ThrHis: 0.975 ± 0.037	2.968ThrIle: 2.968 ± 0.068	1.248ThrLys: 1.248 ± 0.042	5.2ThrLeu: 5.2 ± 0.074	1.328ThrMet: 1.328 ± 0.041	1.436ThrAsn: 1.436 ± 0.047	3.109ThrPro: 3.109 ± 0.062	1.658ThrGln: 1.658 ± 0.046	3.285ThrArg: 3.285 ± 0.07	2.891ThrSer: 2.891 ± 0.069	2.498ThrThr: 2.498 ± 0.06	3.996ThrVal: 3.996 ± 0.081	0.63ThrTrp: 0.63 ± 0.027	1.21ThrTyr: 1.21 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	8.446ValAla: 8.446 ± 0.104	0.555ValCys: 0.555 ± 0.026	4.42ValAsp: 4.42 ± 0.078	4.633ValGlu: 4.633 ± 0.083	2.466ValPhe: 2.466 ± 0.057	5.396ValGly: 5.396 ± 0.096	1.269ValHis: 1.269 ± 0.037	3.927ValIle: 3.927 ± 0.08	1.85ValLys: 1.85 ± 0.056	6.942ValLeu: 6.942 ± 0.112	1.849ValMet: 1.849 ± 0.049	1.975ValAsn: 1.975 ± 0.053	3.746ValPro: 3.746 ± 0.068	2.114ValGln: 2.114 ± 0.05	4.412ValArg: 4.412 ± 0.071	4.139ValSer: 4.139 ± 0.084	4.264ValThr: 4.264 ± 0.078	4.926ValVal: 4.926 ± 0.095	0.903ValTrp: 0.903 ± 0.029	1.309ValTyr: 1.309 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.306TrpAla: 1.306 ± 0.043	0.125TrpCys: 0.125 ± 0.011	0.795TrpAsp: 0.795 ± 0.032	0.679TrpGlu: 0.679 ± 0.026	0.645TrpPhe: 0.645 ± 0.029	0.982TrpGly: 0.982 ± 0.04	0.375TrpHis: 0.375 ± 0.019	0.685TrpIle: 0.685 ± 0.031	0.413TrpLys: 0.413 ± 0.025	1.804TrpLeu: 1.804 ± 0.06	0.401TrpMet: 0.401 ± 0.023	0.464TrpAsn: 0.464 ± 0.024	0.69TrpPro: 0.69 ± 0.032	0.687TrpGln: 0.687 ± 0.033	1.216TrpArg: 1.216 ± 0.042	0.874TrpSer: 0.874 ± 0.034	0.741TrpThr: 0.741 ± 0.031	0.807TrpVal: 0.807 ± 0.034	0.272TrpTrp: 0.272 ± 0.019	0.302TrpTyr: 0.302 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.559TyrAla: 2.559 ± 0.053	0.261TyrCys: 0.261 ± 0.018	1.553TyrAsp: 1.553 ± 0.045	1.281TyrGlu: 1.281 ± 0.047	0.924TyrPhe: 0.924 ± 0.039	2.061TyrGly: 2.061 ± 0.052	0.484TyrHis: 0.484 ± 0.025	0.926TyrIle: 0.926 ± 0.035	0.51TyrLys: 0.51 ± 0.028	2.183TyrLeu: 2.183 ± 0.057	0.437TyrMet: 0.437 ± 0.026	0.637TyrAsn: 0.637 ± 0.031	1.027TyrPro: 1.027 ± 0.035	0.687TyrGln: 0.687 ± 0.03	1.731TyrArg: 1.731 ± 0.047	1.361TyrSer: 1.361 ± 0.043	1.116TyrThr: 1.116 ± 0.04	1.458TyrVal: 1.458 ± 0.043	0.363TyrTrp: 0.363 ± 0.023	0.624TyrTyr: 0.624 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2546 proteins (823728 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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