Feline cyclovirus

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Cyclovirus; Feline associated cyclovirus 1

Average proteome isoelectric point is 8.89

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A076JYW4|A0A076JYW4_9CIRC Capsid protein OS=Feline cyclovirus OX=1530454 PE=4 SV=1
MM1 pKa = 7.28MMTIKK6 pKa = 10.44NYY8 pKa = 8.38KK9 pKa = 5.76TTHH12 pKa = 6.57EE13 pKa = 4.36IGANTPLLEE22 pKa = 4.91KK23 pKa = 9.99KK24 pKa = 8.42TLQQQEE30 pKa = 4.03HH31 pKa = 5.73HH32 pKa = 5.98TFKK35 pKa = 10.52DD36 pKa = 3.2TCKK39 pKa = 10.84YY40 pKa = 10.61NINNLFLYY48 pKa = 10.3RR49 pKa = 11.84HH50 pKa = 6.47FSTSKK55 pKa = 10.17LFKK58 pKa = 9.99TIKK61 pKa = 9.77KK62 pKa = 9.3QLGNEE67 pKa = 3.6IHH69 pKa = 7.12IEE71 pKa = 3.75IARR74 pKa = 11.84GDD76 pKa = 3.68DD77 pKa = 3.79YY78 pKa = 11.85QNKK81 pKa = 9.93DD82 pKa = 3.38YY83 pKa = 9.69CTKK86 pKa = 9.81TDD88 pKa = 3.35KK89 pKa = 10.95EE90 pKa = 4.03AWTWGVPIKK99 pKa = 10.46QGQCTDD105 pKa = 3.49LKK107 pKa = 10.38RR108 pKa = 11.84ACKK111 pKa = 9.9AIKK114 pKa = 9.42EE115 pKa = 4.42GKK117 pKa = 8.3SMKK120 pKa = 10.03YY121 pKa = 9.24ICEE124 pKa = 4.17NFDD127 pKa = 4.58DD128 pKa = 4.28IYY130 pKa = 10.45VRR132 pKa = 11.84YY133 pKa = 8.91WRR135 pKa = 11.84GLYY138 pKa = 9.64KK139 pKa = 10.6LKK141 pKa = 9.6EE142 pKa = 4.25TLAPPPEE149 pKa = 4.4RR150 pKa = 11.84DD151 pKa = 3.52FPTEE155 pKa = 3.41VYY157 pKa = 10.28YY158 pKa = 10.87YY159 pKa = 10.02YY160 pKa = 11.07GEE162 pKa = 4.47PGVGKK167 pKa = 9.68SRR169 pKa = 11.84RR170 pKa = 11.84AYY172 pKa = 10.74SEE174 pKa = 4.37AKK176 pKa = 8.7ATNEE180 pKa = 3.86SIYY183 pKa = 10.47YY184 pKa = 9.72KK185 pKa = 10.52PRR187 pKa = 11.84GDD189 pKa = 2.66WWDD192 pKa = 3.86GYY194 pKa = 7.82EE195 pKa = 3.93QQPNVIIDD203 pKa = 4.32DD204 pKa = 4.42FYY206 pKa = 11.73GWIKK210 pKa = 10.75YY211 pKa = 10.28DD212 pKa = 3.83EE213 pKa = 4.69LLKK216 pKa = 11.02IMDD219 pKa = 4.75RR220 pKa = 11.84YY221 pKa = 9.64PYY223 pKa = 9.85RR224 pKa = 11.84VPVKK228 pKa = 10.39GGYY231 pKa = 9.78QIFNSKK237 pKa = 10.34RR238 pKa = 11.84IWITSNIPIDD248 pKa = 3.58QLYY251 pKa = 9.4KK252 pKa = 9.99HH253 pKa = 6.23SHH255 pKa = 7.53FIPQAIEE262 pKa = 3.85RR263 pKa = 11.84RR264 pKa = 11.84CTKK267 pKa = 10.03IEE269 pKa = 3.84YY270 pKa = 8.2MQQ272 pKa = 4.18

Molecular weight:
32.59 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A076JYW4|A0A076JYW4_9CIRC Capsid protein OS=Feline cyclovirus OX=1530454 PE=4 SV=1
MM1 pKa = 7.94RR2 pKa = 11.84SRR4 pKa = 11.84GVRR7 pKa = 11.84MRR9 pKa = 11.84RR10 pKa = 11.84RR11 pKa = 11.84FFVRR15 pKa = 11.84RR16 pKa = 11.84RR17 pKa = 11.84YY18 pKa = 10.05RR19 pKa = 11.84KK20 pKa = 9.01FFRR23 pKa = 11.84PGYY26 pKa = 7.92RR27 pKa = 11.84ALFRR31 pKa = 11.84RR32 pKa = 11.84YY33 pKa = 8.03YY34 pKa = 9.44RR35 pKa = 11.84PYY37 pKa = 9.83VRR39 pKa = 11.84RR40 pKa = 11.84PHH42 pKa = 6.52NSALNTVLLRR52 pKa = 11.84PNWTDD57 pKa = 3.25NILPTVAKK65 pKa = 9.37TRR67 pKa = 11.84HH68 pKa = 5.53LLSFKK73 pKa = 10.67FDD75 pKa = 4.37DD76 pKa = 4.47LPEE79 pKa = 4.51LEE81 pKa = 4.61KK82 pKa = 10.97FKK84 pKa = 11.36SLFGYY89 pKa = 9.51YY90 pKa = 9.71RR91 pKa = 11.84FVRR94 pKa = 11.84FYY96 pKa = 9.25TKK98 pKa = 10.37CIPKK102 pKa = 8.49VTVLQDD108 pKa = 3.32NTSSGTYY115 pKa = 9.54VAVPWHH121 pKa = 6.77RR122 pKa = 11.84YY123 pKa = 7.72IDD125 pKa = 3.69EE126 pKa = 4.65ASLEE130 pKa = 4.38KK131 pKa = 10.63INADD135 pKa = 3.89DD136 pKa = 5.43LLDD139 pKa = 3.73LTRR142 pKa = 11.84SKK144 pKa = 11.06ARR146 pKa = 11.84RR147 pKa = 11.84CNQVMYY153 pKa = 10.39NSVVPAVVTNSNVLPNSTMRR173 pKa = 11.84TITYY177 pKa = 9.73RR178 pKa = 11.84PWIKK182 pKa = 9.53IDD184 pKa = 3.58RR185 pKa = 11.84DD186 pKa = 3.53GTAVQHH192 pKa = 6.66FGLLYY197 pKa = 10.51AFPSDD202 pKa = 3.53SLHH205 pKa = 5.54ITFQIVTRR213 pKa = 11.84CYY215 pKa = 8.81VQLRR219 pKa = 11.84GYY221 pKa = 10.05SVV223 pKa = 2.89

Molecular weight:
26.63 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

495

223

272

247.5

29.61

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.04 ± 0.308

1.818 ± 0.328

5.455 ± 0.362

4.444 ± 1.838

4.646 ± 1.131

4.444 ± 0.905

2.424 ± 0.126

6.667 ± 1.824

8.081 ± 2.494

6.869 ± 1.456

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.02 ± 0.157

4.646 ± 0.198

5.051 ± 0.229

3.636 ± 0.967

8.889 ± 3.165

4.646 ± 1.131

6.869 ± 0.212

5.455 ± 2.437

2.02 ± 0.468

7.879 ± 0.799

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski