Culex circovirus-like virus

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Circovirus; Mosquito associated circovirus 1

Average proteome isoelectric point is 8.37

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A346M274|A0A346M274_9CIRC Capsid protein OS=Culex circovirus-like virus OX=2304514 PE=4 SV=1
MM1 pKa = 7.14SQIQFVCFTYY11 pKa = 11.0NNYY14 pKa = 9.88PEE16 pKa = 4.31EE17 pKa = 4.75KK18 pKa = 10.2YY19 pKa = 11.13GEE21 pKa = 4.11LLEE24 pKa = 4.28WDD26 pKa = 3.22EE27 pKa = 3.72WRR29 pKa = 11.84YY30 pKa = 9.79VVIGKK35 pKa = 8.96EE36 pKa = 4.19VGEE39 pKa = 4.48SGTPHH44 pKa = 5.64LQGYY48 pKa = 9.51GEE50 pKa = 4.09LKK52 pKa = 9.54KK53 pKa = 10.59RR54 pKa = 11.84KK55 pKa = 9.84RR56 pKa = 11.84FDD58 pKa = 3.09ALKK61 pKa = 9.7RR62 pKa = 11.84KK63 pKa = 8.42WPAVHH68 pKa = 6.45WEE70 pKa = 3.74QRR72 pKa = 11.84RR73 pKa = 11.84ANRR76 pKa = 11.84DD77 pKa = 2.82TAAAYY82 pKa = 8.6CKK84 pKa = 10.42KK85 pKa = 9.82EE86 pKa = 3.48GRR88 pKa = 11.84YY89 pKa = 8.03EE90 pKa = 3.91EE91 pKa = 5.35RR92 pKa = 11.84GVLPEE97 pKa = 3.92NASAKK102 pKa = 9.69SSKK105 pKa = 10.15EE106 pKa = 3.13AVARR110 pKa = 11.84VKK112 pKa = 10.43RR113 pKa = 11.84GEE115 pKa = 4.13SMRR118 pKa = 11.84SIMDD122 pKa = 3.92DD123 pKa = 3.62PPNLSGIRR131 pKa = 11.84VCQLWLSYY139 pKa = 10.82CEE141 pKa = 4.04PKK143 pKa = 10.6RR144 pKa = 11.84NFKK147 pKa = 11.08SEE149 pKa = 3.95VHH151 pKa = 6.47WIYY154 pKa = 11.06GPSGSGKK161 pKa = 7.66TRR163 pKa = 11.84LAATEE168 pKa = 4.69AGDD171 pKa = 3.99DD172 pKa = 4.29SYY174 pKa = 11.7WHH176 pKa = 7.61DD177 pKa = 3.39GTKK180 pKa = 9.78WFDD183 pKa = 3.43GYY185 pKa = 10.84DD186 pKa = 3.11AHH188 pKa = 7.37EE189 pKa = 4.51NMVLDD194 pKa = 4.85DD195 pKa = 4.53FRR197 pKa = 11.84AGNMKK202 pKa = 10.37FNFLLKK208 pKa = 10.17MLDD211 pKa = 3.53RR212 pKa = 11.84YY213 pKa = 9.6PLRR216 pKa = 11.84LEE218 pKa = 4.19CKK220 pKa = 9.49GGYY223 pKa = 8.94RR224 pKa = 11.84QLLSKK229 pKa = 10.62KK230 pKa = 10.48IMITSIKK237 pKa = 9.82HH238 pKa = 5.14PRR240 pKa = 11.84EE241 pKa = 4.47CYY243 pKa = 8.52QQCEE247 pKa = 4.13QDD249 pKa = 4.06EE250 pKa = 4.37PMQQLLHH257 pKa = 7.01IITVQCSVPVLRR269 pKa = 11.84VQNCASITTIFAHH282 pKa = 5.99CTNAQLSHH290 pKa = 7.02LLYY293 pKa = 8.56TTT295 pKa = 4.09

Molecular weight: 34.3 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A346M274|A0A346M274_9CIRC Capsid protein OS=Culex circovirus-like virus OX=2304514 PE=4 SV=1
MM1 pKa = 6.82MAFRR5 pKa = 11.84RR6 pKa = 11.84LTRR9 pKa = 11.84RR10 pKa = 11.84RR11 pKa = 11.84ASKK14 pKa = 9.13RR15 pKa = 11.84TRR17 pKa = 11.84RR18 pKa = 11.84SYY20 pKa = 10.97RR21 pKa = 11.84KK22 pKa = 8.89RR23 pKa = 11.84PSYY26 pKa = 10.44RR27 pKa = 11.84KK28 pKa = 9.03RR29 pKa = 11.84SYY31 pKa = 10.98RR32 pKa = 11.84RR33 pKa = 11.84MNHH36 pKa = 4.13TRR38 pKa = 11.84TVFRR42 pKa = 11.84SFLDD46 pKa = 3.8VPFSTSKK53 pKa = 10.68VFYY56 pKa = 10.72NYY58 pKa = 10.11INNNPSSCAGWHH70 pKa = 5.84YY71 pKa = 10.28YY72 pKa = 10.68ASSFHH77 pKa = 5.79NFKK80 pKa = 9.68VTGFKK85 pKa = 10.21IQFVPRR91 pKa = 11.84ATTAPMEE98 pKa = 4.52AEE100 pKa = 3.93QKK102 pKa = 10.38HH103 pKa = 5.24YY104 pKa = 10.26NASIFISRR112 pKa = 11.84DD113 pKa = 2.86FGNAVWTEE121 pKa = 3.89EE122 pKa = 4.02GDD124 pKa = 3.75NLINKK129 pKa = 8.35CLSIPSTKK137 pKa = 9.41MRR139 pKa = 11.84MLTRR143 pKa = 11.84PTXSXXYY150 pKa = 9.74GXXXXXXXXQPTKK163 pKa = 10.97

Molecular weight: 18.06 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

458

163

295

229.0

26.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.895 ± 0.219

2.62 ± 0.818

3.712 ± 1.099

5.895 ± 2.02

4.367 ± 1.398

5.24 ± 1.276

2.838 ± 0.226

3.93 ± 0.146

6.987 ± 0.5

6.332 ± 1.917

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

3.057 ± 0.366

4.585 ± 0.91

4.367 ± 0.318

3.712 ± 1.099

8.952 ± 1.948

7.424 ± 1.405

5.677 ± 1.35

4.585 ± 0.531

2.183 ± 0.562

5.24 ± 0.165
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski