Amino acid dipepetide frequency for Fisavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.272AlaAla: 3.272 ± 0.0
0.0AlaCys: 0.0 ± 0.0
1.454AlaAsp: 1.454 ± 0.0
2.908AlaGlu: 2.908 ± 0.0
2.181AlaPhe: 2.181 ± 0.0
2.908AlaGly: 2.908 ± 0.0
0.727AlaHis: 0.727 ± 0.0
5.453AlaIle: 5.453 ± 0.0
5.089AlaLys: 5.089 ± 0.0
4.362AlaLeu: 4.362 ± 0.0
1.091AlaMet: 1.091 ± 0.0
1.818AlaAsn: 1.818 ± 0.0
3.272AlaPro: 3.272 ± 0.0
3.272AlaGln: 3.272 ± 0.0
2.545AlaArg: 2.545 ± 0.0
5.453AlaSer: 5.453 ± 0.0
2.908AlaThr: 2.908 ± 0.0
3.999AlaVal: 3.999 ± 0.0
0.364AlaTrp: 0.364 ± 0.0
2.908AlaTyr: 2.908 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.364CysAla: 0.364 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.727CysAsp: 0.727 ± 0.0
0.364CysGlu: 0.364 ± 0.0
2.181CysPhe: 2.181 ± 0.0
1.454CysGly: 1.454 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.091CysIle: 1.091 ± 0.0
1.818CysLys: 1.818 ± 0.0
1.818CysLeu: 1.818 ± 0.0
0.364CysMet: 0.364 ± 0.0
0.727CysAsn: 0.727 ± 0.0
1.091CysPro: 1.091 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.727CysArg: 0.727 ± 0.0
1.454CysSer: 1.454 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.091CysVal: 1.091 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.727CysTyr: 0.727 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.091AspAla: 1.091 ± 0.0
1.818AspCys: 1.818 ± 0.0
4.362AspAsp: 4.362 ± 0.0
3.999AspGlu: 3.999 ± 0.0
3.999AspPhe: 3.999 ± 0.0
3.272AspGly: 3.272 ± 0.0
1.091AspHis: 1.091 ± 0.0
4.362AspIle: 4.362 ± 0.0
3.272AspLys: 3.272 ± 0.0
3.272AspLeu: 3.272 ± 0.0
2.908AspMet: 2.908 ± 0.0
1.818AspAsn: 1.818 ± 0.0
4.726AspPro: 4.726 ± 0.0
1.091AspGln: 1.091 ± 0.0
1.454AspArg: 1.454 ± 0.0
2.908AspSer: 2.908 ± 0.0
3.272AspThr: 3.272 ± 0.0
4.726AspVal: 4.726 ± 0.0
0.364AspTrp: 0.364 ± 0.0
1.454AspTyr: 1.454 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.543GluAla: 6.543 ± 0.0
0.364GluCys: 0.364 ± 0.0
4.726GluAsp: 4.726 ± 0.0
4.726GluGlu: 4.726 ± 0.0
4.362GluPhe: 4.362 ± 0.0
4.362GluGly: 4.362 ± 0.0
1.454GluHis: 1.454 ± 0.0
4.726GluIle: 4.726 ± 0.0
4.362GluLys: 4.362 ± 0.0
7.27GluLeu: 7.27 ± 0.0
1.818GluMet: 1.818 ± 0.0
1.818GluAsn: 1.818 ± 0.0
1.454GluPro: 1.454 ± 0.0
1.818GluGln: 1.818 ± 0.0
0.727GluArg: 0.727 ± 0.0
4.362GluSer: 4.362 ± 0.0
2.908GluThr: 2.908 ± 0.0
3.999GluVal: 3.999 ± 0.0
0.0GluTrp: 0.0 ± 0.0
2.181GluTyr: 2.181 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.181PheAla: 2.181 ± 0.0
2.181PheCys: 2.181 ± 0.0
4.362PheAsp: 4.362 ± 0.0
4.362PheGlu: 4.362 ± 0.0
2.545PhePhe: 2.545 ± 0.0
3.635PheGly: 3.635 ± 0.0
0.727PheHis: 0.727 ± 0.0
1.818PheIle: 1.818 ± 0.0
2.181PheLys: 2.181 ± 0.0
6.18PheLeu: 6.18 ± 0.0
0.727PheMet: 0.727 ± 0.0
1.454PheAsn: 1.454 ± 0.0
2.181PhePro: 2.181 ± 0.0
2.545PheGln: 2.545 ± 0.0
2.545PheArg: 2.545 ± 0.0
4.726PheSer: 4.726 ± 0.0
5.089PheThr: 5.089 ± 0.0
4.362PheVal: 4.362 ± 0.0
1.454PheTrp: 1.454 ± 0.0
1.818PheTyr: 1.818 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.635GlyAla: 3.635 ± 0.0
0.364GlyCys: 0.364 ± 0.0
3.999GlyAsp: 3.999 ± 0.0
3.635GlyGlu: 3.635 ± 0.0
1.818GlyPhe: 1.818 ± 0.0
4.362GlyGly: 4.362 ± 0.0
0.364GlyHis: 0.364 ± 0.0
3.272GlyIle: 3.272 ± 0.0
7.27GlyLys: 7.27 ± 0.0
6.18GlyLeu: 6.18 ± 0.0
1.454GlyMet: 1.454 ± 0.0
2.908GlyAsn: 2.908 ± 0.0
2.545GlyPro: 2.545 ± 0.0
1.818GlyGln: 1.818 ± 0.0
1.818GlyArg: 1.818 ± 0.0
2.908GlySer: 2.908 ± 0.0
5.816GlyThr: 5.816 ± 0.0
4.726GlyVal: 4.726 ± 0.0
0.364GlyTrp: 0.364 ± 0.0
2.545GlyTyr: 2.545 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.091HisAla: 1.091 ± 0.0
0.727HisCys: 0.727 ± 0.0
0.364HisAsp: 0.364 ± 0.0
0.727HisGlu: 0.727 ± 0.0
0.727HisPhe: 0.727 ± 0.0
1.091HisGly: 1.091 ± 0.0
1.454HisHis: 1.454 ± 0.0
1.454HisIle: 1.454 ± 0.0
0.727HisLys: 0.727 ± 0.0
1.091HisLeu: 1.091 ± 0.0
0.364HisMet: 0.364 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.727HisPro: 0.727 ± 0.0
0.727HisGln: 0.727 ± 0.0
1.818HisArg: 1.818 ± 0.0
1.454HisSer: 1.454 ± 0.0
0.364HisThr: 0.364 ± 0.0
0.727HisVal: 0.727 ± 0.0
0.727HisTrp: 0.727 ± 0.0
0.364HisTyr: 0.364 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.545IleAla: 2.545 ± 0.0
1.454IleCys: 1.454 ± 0.0
4.726IleAsp: 4.726 ± 0.0
5.089IleGlu: 5.089 ± 0.0
4.362IlePhe: 4.362 ± 0.0
5.453IleGly: 5.453 ± 0.0
1.091IleHis: 1.091 ± 0.0
4.362IleIle: 4.362 ± 0.0
3.272IleLys: 3.272 ± 0.0
4.726IleLeu: 4.726 ± 0.0
1.454IleMet: 1.454 ± 0.0
3.272IleAsn: 3.272 ± 0.0
5.816IlePro: 5.816 ± 0.0
1.454IleGln: 1.454 ± 0.0
4.726IleArg: 4.726 ± 0.0
3.999IleSer: 3.999 ± 0.0
3.635IleThr: 3.635 ± 0.0
4.362IleVal: 4.362 ± 0.0
0.727IleTrp: 0.727 ± 0.0
2.908IleTyr: 2.908 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.908LysAla: 2.908 ± 0.0
0.364LysCys: 0.364 ± 0.0
4.726LysAsp: 4.726 ± 0.0
2.545LysGlu: 2.545 ± 0.0
5.816LysPhe: 5.816 ± 0.0
3.272LysGly: 3.272 ± 0.0
1.454LysHis: 1.454 ± 0.0
3.999LysIle: 3.999 ± 0.0
2.545LysLys: 2.545 ± 0.0
5.453LysLeu: 5.453 ± 0.0
2.545LysMet: 2.545 ± 0.0
4.362LysAsn: 4.362 ± 0.0
3.272LysPro: 3.272 ± 0.0
3.272LysGln: 3.272 ± 0.0
2.908LysArg: 2.908 ± 0.0
3.999LysSer: 3.999 ± 0.0
5.453LysThr: 5.453 ± 0.0
4.726LysVal: 4.726 ± 0.0
1.454LysTrp: 1.454 ± 0.0
1.091LysTyr: 1.091 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.089LeuAla: 5.089 ± 0.0
2.908LeuCys: 2.908 ± 0.0
3.272LeuAsp: 3.272 ± 0.0
6.18LeuGlu: 6.18 ± 0.0
3.272LeuPhe: 3.272 ± 0.0
6.907LeuGly: 6.907 ± 0.0
1.454LeuHis: 1.454 ± 0.0
2.908LeuIle: 2.908 ± 0.0
6.18LeuLys: 6.18 ± 0.0
5.453LeuLeu: 5.453 ± 0.0
1.091LeuMet: 1.091 ± 0.0
4.726LeuAsn: 4.726 ± 0.0
3.635LeuPro: 3.635 ± 0.0
1.454LeuGln: 1.454 ± 0.0
4.726LeuArg: 4.726 ± 0.0
6.907LeuSer: 6.907 ± 0.0
5.453LeuThr: 5.453 ± 0.0
5.816LeuVal: 5.816 ± 0.0
0.364LeuTrp: 0.364 ± 0.0
1.818LeuTyr: 1.818 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.091MetAla: 1.091 ± 0.0
0.727MetCys: 0.727 ± 0.0
0.727MetAsp: 0.727 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.364MetGly: 0.364 ± 0.0
0.364MetHis: 0.364 ± 0.0
1.454MetIle: 1.454 ± 0.0
2.908MetLys: 2.908 ± 0.0
1.454MetLeu: 1.454 ± 0.0
0.364MetMet: 0.364 ± 0.0
3.272MetAsn: 3.272 ± 0.0
2.181MetPro: 2.181 ± 0.0
0.727MetGln: 0.727 ± 0.0
1.091MetArg: 1.091 ± 0.0
1.454MetSer: 1.454 ± 0.0
1.454MetThr: 1.454 ± 0.0
1.454MetVal: 1.454 ± 0.0
0.364MetTrp: 0.364 ± 0.0
1.818MetTyr: 1.818 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.545AsnAla: 2.545 ± 0.0
0.0AsnCys: 0.0 ± 0.0
2.545AsnAsp: 2.545 ± 0.0
5.453AsnGlu: 5.453 ± 0.0
3.999AsnPhe: 3.999 ± 0.0
3.635AsnGly: 3.635 ± 0.0
0.364AsnHis: 0.364 ± 0.0
3.272AsnIle: 3.272 ± 0.0
2.545AsnLys: 2.545 ± 0.0
4.726AsnLeu: 4.726 ± 0.0
1.454AsnMet: 1.454 ± 0.0
2.545AsnAsn: 2.545 ± 0.0
2.181AsnPro: 2.181 ± 0.0
1.091AsnGln: 1.091 ± 0.0
1.454AsnArg: 1.454 ± 0.0
3.272AsnSer: 3.272 ± 0.0
3.999AsnThr: 3.999 ± 0.0
3.635AsnVal: 3.635 ± 0.0
1.091AsnTrp: 1.091 ± 0.0
2.181AsnTyr: 2.181 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.181ProAla: 2.181 ± 0.0
0.364ProCys: 0.364 ± 0.0
3.635ProAsp: 3.635 ± 0.0
4.362ProGlu: 4.362 ± 0.0
3.272ProPhe: 3.272 ± 0.0
2.181ProGly: 2.181 ± 0.0
0.364ProHis: 0.364 ± 0.0
7.27ProIle: 7.27 ± 0.0
2.908ProLys: 2.908 ± 0.0
3.635ProLeu: 3.635 ± 0.0
0.727ProMet: 0.727 ± 0.0
2.181ProAsn: 2.181 ± 0.0
2.181ProPro: 2.181 ± 0.0
1.454ProGln: 1.454 ± 0.0
2.545ProArg: 2.545 ± 0.0
3.999ProSer: 3.999 ± 0.0
3.272ProThr: 3.272 ± 0.0
4.362ProVal: 4.362 ± 0.0
0.364ProTrp: 0.364 ± 0.0
1.091ProTyr: 1.091 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.818GlnAla: 1.818 ± 0.0
0.727GlnCys: 0.727 ± 0.0
1.091GlnAsp: 1.091 ± 0.0
2.908GlnGlu: 2.908 ± 0.0
3.635GlnPhe: 3.635 ± 0.0
4.726GlnGly: 4.726 ± 0.0
0.727GlnHis: 0.727 ± 0.0
2.181GlnIle: 2.181 ± 0.0
1.091GlnLys: 1.091 ± 0.0
1.454GlnLeu: 1.454 ± 0.0
0.364GlnMet: 0.364 ± 0.0
1.818GlnAsn: 1.818 ± 0.0
0.727GlnPro: 0.727 ± 0.0
2.545GlnGln: 2.545 ± 0.0
1.091GlnArg: 1.091 ± 0.0
2.181GlnSer: 2.181 ± 0.0
2.181GlnThr: 2.181 ± 0.0
2.181GlnVal: 2.181 ± 0.0
0.364GlnTrp: 0.364 ± 0.0
1.454GlnTyr: 1.454 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.272ArgAla: 3.272 ± 0.0
0.727ArgCys: 0.727 ± 0.0
2.181ArgAsp: 2.181 ± 0.0
5.089ArgGlu: 5.089 ± 0.0
2.181ArgPhe: 2.181 ± 0.0
1.454ArgGly: 1.454 ± 0.0
0.727ArgHis: 0.727 ± 0.0
2.908ArgIle: 2.908 ± 0.0
2.545ArgLys: 2.545 ± 0.0
3.272ArgLeu: 3.272 ± 0.0
1.818ArgMet: 1.818 ± 0.0
4.362ArgAsn: 4.362 ± 0.0
2.181ArgPro: 2.181 ± 0.0
0.364ArgGln: 0.364 ± 0.0
2.908ArgArg: 2.908 ± 0.0
3.272ArgSer: 3.272 ± 0.0
1.454ArgThr: 1.454 ± 0.0
1.091ArgVal: 1.091 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
0.727ArgTyr: 0.727 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.453SerAla: 5.453 ± 0.0
0.364SerCys: 0.364 ± 0.0
4.726SerAsp: 4.726 ± 0.0
3.635SerGlu: 3.635 ± 0.0
3.272SerPhe: 3.272 ± 0.0
2.908SerGly: 2.908 ± 0.0
1.454SerHis: 1.454 ± 0.0
4.726SerIle: 4.726 ± 0.0
3.635SerLys: 3.635 ± 0.0
5.089SerLeu: 5.089 ± 0.0
2.181SerMet: 2.181 ± 0.0
4.362SerAsn: 4.362 ± 0.0
2.908SerPro: 2.908 ± 0.0
3.272SerGln: 3.272 ± 0.0
1.091SerArg: 1.091 ± 0.0
9.088SerSer: 9.088 ± 0.0
4.726SerThr: 4.726 ± 0.0
6.18SerVal: 6.18 ± 0.0
1.091SerTrp: 1.091 ± 0.0
3.635SerTyr: 3.635 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.635ThrAla: 3.635 ± 0.0
1.454ThrCys: 1.454 ± 0.0
1.818ThrAsp: 1.818 ± 0.0
1.818ThrGlu: 1.818 ± 0.0
2.181ThrPhe: 2.181 ± 0.0
4.362ThrGly: 4.362 ± 0.0
1.454ThrHis: 1.454 ± 0.0
5.089ThrIle: 5.089 ± 0.0
6.543ThrLys: 6.543 ± 0.0
6.18ThrLeu: 6.18 ± 0.0
0.727ThrMet: 0.727 ± 0.0
3.635ThrAsn: 3.635 ± 0.0
2.908ThrPro: 2.908 ± 0.0
3.635ThrGln: 3.635 ± 0.0
2.545ThrArg: 2.545 ± 0.0
6.18ThrSer: 6.18 ± 0.0
6.18ThrThr: 6.18 ± 0.0
3.635ThrVal: 3.635 ± 0.0
0.727ThrTrp: 0.727 ± 0.0
2.181ThrTyr: 2.181 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.816ValAla: 5.816 ± 0.0
0.727ValCys: 0.727 ± 0.0
3.272ValAsp: 3.272 ± 0.0
4.726ValGlu: 4.726 ± 0.0
4.362ValPhe: 4.362 ± 0.0
2.908ValGly: 2.908 ± 0.0
1.454ValHis: 1.454 ± 0.0
5.816ValIle: 5.816 ± 0.0
3.635ValLys: 3.635 ± 0.0
3.635ValLeu: 3.635 ± 0.0
1.454ValMet: 1.454 ± 0.0
3.272ValAsn: 3.272 ± 0.0
6.18ValPro: 6.18 ± 0.0
2.545ValGln: 2.545 ± 0.0
1.818ValArg: 1.818 ± 0.0
3.272ValSer: 3.272 ± 0.0
6.543ValThr: 6.543 ± 0.0
2.908ValVal: 2.908 ± 0.0
0.727ValTrp: 0.727 ± 0.0
1.454ValTyr: 1.454 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.364TrpAla: 0.364 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.364TrpAsp: 0.364 ± 0.0
0.727TrpGlu: 0.727 ± 0.0
0.364TrpPhe: 0.364 ± 0.0
1.091TrpGly: 1.091 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.091TrpIle: 1.091 ± 0.0
0.727TrpLys: 0.727 ± 0.0
1.454TrpLeu: 1.454 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.727TrpAsn: 0.727 ± 0.0
0.364TrpPro: 0.364 ± 0.0
0.364TrpGln: 0.364 ± 0.0
1.454TrpArg: 1.454 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.091TrpThr: 1.091 ± 0.0
0.727TrpVal: 0.727 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.364TrpTyr: 0.364 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.091TyrAla: 1.091 ± 0.0
0.727TyrCys: 0.727 ± 0.0
2.181TyrAsp: 2.181 ± 0.0
1.091TyrGlu: 1.091 ± 0.0
2.545TyrPhe: 2.545 ± 0.0
1.454TyrGly: 1.454 ± 0.0
0.0TyrHis: 0.0 ± 0.0
2.181TyrIle: 2.181 ± 0.0
2.908TyrLys: 2.908 ± 0.0
2.908TyrLeu: 2.908 ± 0.0
0.0TyrMet: 0.0 ± 0.0
2.908TyrAsn: 2.908 ± 0.0
1.818TyrPro: 1.818 ± 0.0
1.818TyrGln: 1.818 ± 0.0
2.545TyrArg: 2.545 ± 0.0
2.908TyrSer: 2.908 ± 0.0
1.091TyrThr: 1.091 ± 0.0
1.818TyrVal: 1.818 ± 0.0
0.727TyrTrp: 0.727 ± 0.0
1.454TyrTyr: 1.454 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2752 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski