Amino acid dipepetide frequency for Beihai picorna-like virus 91

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.025AlaAla: 4.025 ± 0.803
2.561AlaCys: 2.561 ± 0.805
3.293AlaAsp: 3.293 ± 1.808
3.659AlaGlu: 3.659 ± 0.202
2.561AlaPhe: 2.561 ± 0.202
2.561AlaGly: 2.561 ± 0.805
3.659AlaHis: 3.659 ± 0.202
4.025AlaIle: 4.025 ± 0.403
2.927AlaLys: 2.927 ± 0.803
4.757AlaLeu: 4.757 ± 1.408
0.366AlaMet: 0.366 ± 0.402
1.829AlaAsn: 1.829 ± 0.2
4.391AlaPro: 4.391 ± 1.205
3.659AlaGln: 3.659 ± 0.401
3.659AlaArg: 3.659 ± 2.011
2.927AlaSer: 2.927 ± 0.2
2.927AlaThr: 2.927 ± 0.2
2.927AlaVal: 2.927 ± 0.2
0.732AlaTrp: 0.732 ± 0.201
1.829AlaTyr: 1.829 ± 0.803
0.0AlaXaa: 0.0 ± 0.0
Cys
0.732CysAla: 0.732 ± 0.402
1.098CysCys: 1.098 ± 0.0
2.561CysAsp: 2.561 ± 0.805
1.829CysGlu: 1.829 ± 0.403
1.464CysPhe: 1.464 ± 0.804
1.464CysGly: 1.464 ± 0.804
0.366CysHis: 0.366 ± 0.201
0.732CysIle: 0.732 ± 0.201
1.098CysLys: 1.098 ± 0.603
1.829CysLeu: 1.829 ± 1.005
0.732CysMet: 0.732 ± 0.402
1.464CysAsn: 1.464 ± 0.804
1.098CysPro: 1.098 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.464CysArg: 1.464 ± 0.201
1.464CysSer: 1.464 ± 0.201
0.366CysThr: 0.366 ± 0.201
1.464CysVal: 1.464 ± 0.804
0.0CysTrp: 0.0 ± 0.0
0.732CysTyr: 0.732 ± 0.402
0.0CysXaa: 0.0 ± 0.0
Asp
4.025AspAla: 4.025 ± 0.403
0.732AspCys: 0.732 ± 0.402
4.025AspAsp: 4.025 ± 2.009
4.757AspGlu: 4.757 ± 0.805
2.561AspPhe: 2.561 ± 0.401
7.318AspGly: 7.318 ± 0.404
1.098AspHis: 1.098 ± 0.603
5.123AspIle: 5.123 ± 2.611
3.659AspLys: 3.659 ± 1.408
3.659AspLeu: 3.659 ± 1.004
1.098AspMet: 1.098 ± 0.603
2.561AspAsn: 2.561 ± 0.401
2.195AspPro: 2.195 ± 0.604
4.757AspGln: 4.757 ± 0.202
1.464AspArg: 1.464 ± 0.201
2.561AspSer: 2.561 ± 1.004
4.025AspThr: 4.025 ± 0.803
4.025AspVal: 4.025 ± 0.803
1.098AspTrp: 1.098 ± 0.603
2.561AspTyr: 2.561 ± 0.401
0.0AspXaa: 0.0 ± 0.0
Glu
2.927GluAla: 2.927 ± 0.403
2.195GluCys: 2.195 ± 1.207
3.659GluAsp: 3.659 ± 0.202
4.025GluGlu: 4.025 ± 1.609
3.293GluPhe: 3.293 ± 0.001
1.464GluGly: 1.464 ± 0.201
0.366GluHis: 0.366 ± 0.402
4.391GluIle: 4.391 ± 1.207
5.488GluLys: 5.488 ± 1.208
3.659GluLeu: 3.659 ± 0.401
1.464GluMet: 1.464 ± 0.402
3.293GluAsn: 3.293 ± 0.604
2.195GluPro: 2.195 ± 1.205
2.561GluGln: 2.561 ± 0.805
2.561GluArg: 2.561 ± 0.805
4.025GluSer: 4.025 ± 1.006
4.025GluThr: 4.025 ± 1.609
5.123GluVal: 5.123 ± 0.199
0.366GluTrp: 0.366 ± 0.402
2.195GluTyr: 2.195 ± 1.207
0.0GluXaa: 0.0 ± 0.0
Phe
2.195PheAla: 2.195 ± 0.001
1.829PheCys: 1.829 ± 0.2
2.927PheAsp: 2.927 ± 0.403
1.464PheGlu: 1.464 ± 0.804
1.098PhePhe: 1.098 ± 0.0
2.927PheGly: 2.927 ± 0.2
0.366PheHis: 0.366 ± 0.402
2.561PheIle: 2.561 ± 0.805
2.195PheLys: 2.195 ± 1.207
1.464PheLeu: 1.464 ± 0.201
1.098PheMet: 1.098 ± 0.0
1.829PheAsn: 1.829 ± 0.403
1.464PhePro: 1.464 ± 1.004
2.561PheGln: 2.561 ± 1.607
2.927PheArg: 2.927 ± 1.006
4.757PheSer: 4.757 ± 1.408
4.025PheThr: 4.025 ± 1.406
3.659PheVal: 3.659 ± 0.202
0.366PheTrp: 0.366 ± 0.201
2.195PheTyr: 2.195 ± 1.808
0.0PheXaa: 0.0 ± 0.0
Gly
1.829GlyAla: 1.829 ± 1.406
0.0GlyCys: 0.0 ± 0.0
4.025GlyAsp: 4.025 ± 0.403
5.854GlyGlu: 5.854 ± 0.4
2.561GlyPhe: 2.561 ± 0.202
1.829GlyGly: 1.829 ± 0.2
1.829GlyHis: 1.829 ± 1.005
5.123GlyIle: 5.123 ± 0.199
4.757GlyLys: 4.757 ± 2.614
4.025GlyLeu: 4.025 ± 0.2
0.366GlyMet: 0.366 ± 0.402
3.293GlyAsn: 3.293 ± 0.602
0.732GlyPro: 0.732 ± 0.201
1.098GlyGln: 1.098 ± 0.603
3.659GlyArg: 3.659 ± 0.202
2.561GlySer: 2.561 ± 1.004
3.293GlyThr: 3.293 ± 1.205
5.488GlyVal: 5.488 ± 0.002
1.098GlyTrp: 1.098 ± 0.603
1.464GlyTyr: 1.464 ± 0.804
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.732HisCys: 0.732 ± 0.402
2.561HisAsp: 2.561 ± 0.202
1.464HisGlu: 1.464 ± 0.804
0.732HisPhe: 0.732 ± 0.402
1.829HisGly: 1.829 ± 0.403
0.732HisHis: 0.732 ± 0.402
1.098HisIle: 1.098 ± 0.0
2.927HisLys: 2.927 ± 1.006
1.098HisLeu: 1.098 ± 0.603
0.366HisMet: 0.366 ± 0.201
0.366HisAsn: 0.366 ± 0.201
2.195HisPro: 2.195 ± 0.602
2.195HisGln: 2.195 ± 0.604
1.098HisArg: 1.098 ± 0.0
1.464HisSer: 1.464 ± 0.804
0.366HisThr: 0.366 ± 0.201
1.098HisVal: 1.098 ± 0.0
0.366HisTrp: 0.366 ± 0.402
0.732HisTyr: 0.732 ± 0.402
0.0HisXaa: 0.0 ± 0.0
Ile
6.952IleAla: 6.952 ± 0.4
0.0IleCys: 0.0 ± 0.0
5.854IleAsp: 5.854 ± 2.209
5.854IleGlu: 5.854 ± 0.806
2.927IlePhe: 2.927 ± 0.403
3.659IleGly: 3.659 ± 2.813
0.732IleHis: 0.732 ± 0.402
5.488IleIle: 5.488 ± 0.002
3.293IleLys: 3.293 ± 1.81
3.293IleLeu: 3.293 ± 1.207
1.098IleMet: 1.098 ± 0.603
5.123IleAsn: 5.123 ± 0.802
1.464IlePro: 1.464 ± 1.004
2.927IleGln: 2.927 ± 0.2
3.659IleArg: 3.659 ± 0.202
3.659IleSer: 3.659 ± 0.202
5.488IleThr: 5.488 ± 0.002
5.854IleVal: 5.854 ± 1.003
0.366IleTrp: 0.366 ± 0.201
2.195IleTyr: 2.195 ± 0.604
0.0IleXaa: 0.0 ± 0.0
Lys
4.025LysAla: 4.025 ± 0.403
2.561LysCys: 2.561 ± 0.805
2.561LysAsp: 2.561 ± 0.202
1.829LysGlu: 1.829 ± 1.005
1.098LysPhe: 1.098 ± 0.0
3.659LysGly: 3.659 ± 0.805
1.098LysHis: 1.098 ± 0.603
4.025LysIle: 4.025 ± 2.212
3.293LysLys: 3.293 ± 1.207
5.854LysLeu: 5.854 ± 0.806
1.829LysMet: 1.829 ± 0.403
2.561LysAsn: 2.561 ± 0.805
2.561LysPro: 2.561 ± 0.202
3.293LysGln: 3.293 ± 0.001
2.927LysArg: 2.927 ± 1.609
3.659LysSer: 3.659 ± 1.004
4.391LysThr: 4.391 ± 1.207
6.586LysVal: 6.586 ± 1.208
1.098LysTrp: 1.098 ± 0.0
2.927LysTyr: 2.927 ± 1.006
0.0LysXaa: 0.0 ± 0.0
Leu
4.757LeuAla: 4.757 ± 0.202
2.561LeuCys: 2.561 ± 1.408
4.757LeuAsp: 4.757 ± 1.408
1.829LeuGlu: 1.829 ± 0.2
5.854LeuPhe: 5.854 ± 2.012
2.195LeuGly: 2.195 ± 0.001
1.829LeuHis: 1.829 ± 1.005
4.391LeuIle: 4.391 ± 0.604
5.488LeuLys: 5.488 ± 0.002
6.586LeuLeu: 6.586 ± 1.811
1.829LeuMet: 1.829 ± 0.403
4.391LeuAsn: 4.391 ± 0.602
2.195LeuPro: 2.195 ± 0.604
1.829LeuGln: 1.829 ± 0.803
2.561LeuArg: 2.561 ± 0.401
5.854LeuSer: 5.854 ± 0.4
5.854LeuThr: 5.854 ± 0.203
3.659LeuVal: 3.659 ± 1.004
1.098LeuTrp: 1.098 ± 0.0
4.025LeuTyr: 4.025 ± 0.2
0.0LeuXaa: 0.0 ± 0.0
Met
1.829MetAla: 1.829 ± 0.2
0.366MetCys: 0.366 ± 0.201
2.561MetAsp: 2.561 ± 0.401
1.098MetGlu: 1.098 ± 0.603
0.366MetPhe: 0.366 ± 0.201
0.366MetGly: 0.366 ± 0.402
0.0MetHis: 0.0 ± 0.0
1.464MetIle: 1.464 ± 0.804
1.829MetLys: 1.829 ± 0.403
1.098MetLeu: 1.098 ± 0.603
0.732MetMet: 0.732 ± 0.324
0.732MetAsn: 0.732 ± 0.201
0.732MetPro: 0.732 ± 0.804
0.732MetGln: 0.732 ± 0.402
1.098MetArg: 1.098 ± 0.603
2.561MetSer: 2.561 ± 0.202
2.927MetThr: 2.927 ± 0.403
1.464MetVal: 1.464 ± 0.201
0.732MetTrp: 0.732 ± 0.201
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.123AsnAla: 5.123 ± 2.212
1.098AsnCys: 1.098 ± 0.603
2.195AsnAsp: 2.195 ± 0.001
3.659AsnGlu: 3.659 ± 1.004
2.195AsnPhe: 2.195 ± 0.001
2.561AsnGly: 2.561 ± 0.401
1.829AsnHis: 1.829 ± 0.2
5.488AsnIle: 5.488 ± 0.002
2.561AsnLys: 2.561 ± 0.401
3.293AsnLeu: 3.293 ± 0.602
1.098AsnMet: 1.098 ± 0.603
1.464AsnAsn: 1.464 ± 0.804
4.025AsnPro: 4.025 ± 0.403
1.464AsnGln: 1.464 ± 0.402
1.464AsnArg: 1.464 ± 0.804
4.391AsnSer: 4.391 ± 0.001
2.927AsnThr: 2.927 ± 0.803
1.829AsnVal: 1.829 ± 0.2
0.366AsnTrp: 0.366 ± 0.201
1.464AsnTyr: 1.464 ± 0.804
0.0AsnXaa: 0.0 ± 0.0
Pro
2.195ProAla: 2.195 ± 1.205
0.366ProCys: 0.366 ± 0.201
2.195ProAsp: 2.195 ± 0.602
1.098ProGlu: 1.098 ± 0.603
2.927ProPhe: 2.927 ± 0.2
3.659ProGly: 3.659 ± 0.805
0.0ProHis: 0.0 ± 0.0
4.025ProIle: 4.025 ± 1.406
0.366ProLys: 0.366 ± 0.201
2.927ProLeu: 2.927 ± 0.2
0.732ProMet: 0.732 ± 0.402
2.195ProAsn: 2.195 ± 0.001
0.732ProPro: 0.732 ± 0.201
0.732ProGln: 0.732 ± 0.201
1.464ProArg: 1.464 ± 0.201
4.757ProSer: 4.757 ± 3.415
1.098ProThr: 1.098 ± 0.0
4.025ProVal: 4.025 ± 0.803
0.0ProTrp: 0.0 ± 0.0
2.927ProTyr: 2.927 ± 0.803
0.0ProXaa: 0.0 ± 0.0
Gln
2.195GlnAla: 2.195 ± 0.001
0.732GlnCys: 0.732 ± 0.402
4.391GlnAsp: 4.391 ± 1.207
4.025GlnGlu: 4.025 ± 1.006
0.366GlnPhe: 0.366 ± 0.402
2.927GlnGly: 2.927 ± 2.009
0.732GlnHis: 0.732 ± 0.201
2.561GlnIle: 2.561 ± 0.401
1.829GlnLys: 1.829 ± 1.005
4.391GlnLeu: 4.391 ± 1.81
1.098GlnMet: 1.098 ± 0.0
2.195GlnAsn: 2.195 ± 1.808
1.098GlnPro: 1.098 ± 0.603
1.464GlnGln: 1.464 ± 0.402
2.195GlnArg: 2.195 ± 1.205
1.464GlnSer: 1.464 ± 1.004
2.561GlnThr: 2.561 ± 0.401
4.025GlnVal: 4.025 ± 0.803
0.366GlnTrp: 0.366 ± 0.201
1.464GlnTyr: 1.464 ± 1.004
0.0GlnXaa: 0.0 ± 0.0
Arg
2.561ArgAla: 2.561 ± 1.004
0.732ArgCys: 0.732 ± 0.402
2.195ArgAsp: 2.195 ± 0.602
2.195ArgGlu: 2.195 ± 1.207
0.732ArgPhe: 0.732 ± 0.804
1.464ArgGly: 1.464 ± 0.201
0.732ArgHis: 0.732 ± 0.402
4.025ArgIle: 4.025 ± 0.2
3.659ArgLys: 3.659 ± 2.011
3.293ArgLeu: 3.293 ± 0.604
0.732ArgMet: 0.732 ± 0.238
2.927ArgAsn: 2.927 ± 1.006
1.464ArgPro: 1.464 ± 0.402
1.464ArgGln: 1.464 ± 0.201
3.659ArgArg: 3.659 ± 0.805
5.488ArgSer: 5.488 ± 0.605
2.195ArgThr: 2.195 ± 0.001
4.757ArgVal: 4.757 ± 1.003
0.366ArgTrp: 0.366 ± 0.402
1.098ArgTyr: 1.098 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.025SerAla: 4.025 ± 2.009
0.732SerCys: 0.732 ± 0.402
2.561SerAsp: 2.561 ± 0.805
2.561SerGlu: 2.561 ± 1.004
3.659SerPhe: 3.659 ± 1.607
5.123SerGly: 5.123 ± 0.199
3.293SerHis: 3.293 ± 0.604
4.391SerIle: 4.391 ± 0.602
4.757SerLys: 4.757 ± 0.401
8.782SerLeu: 8.782 ± 0.6
1.464SerMet: 1.464 ± 0.201
4.391SerAsn: 4.391 ± 0.001
3.293SerPro: 3.293 ± 0.001
3.659SerGln: 3.659 ± 1.004
3.293SerArg: 3.293 ± 1.205
4.025SerSer: 4.025 ± 1.406
4.757SerThr: 4.757 ± 0.401
6.22SerVal: 6.22 ± 1.405
0.732SerTrp: 0.732 ± 0.201
3.293SerTyr: 3.293 ± 0.001
0.0SerXaa: 0.0 ± 0.0
Thr
3.293ThrAla: 3.293 ± 1.81
0.366ThrCys: 0.366 ± 0.402
3.659ThrAsp: 3.659 ± 0.401
4.025ThrGlu: 4.025 ± 1.006
3.293ThrPhe: 3.293 ± 0.602
3.293ThrGly: 3.293 ± 0.604
1.464ThrHis: 1.464 ± 0.201
3.293ThrIle: 3.293 ± 1.205
3.659ThrLys: 3.659 ± 0.202
5.488ThrLeu: 5.488 ± 1.208
2.195ThrMet: 2.195 ± 0.602
2.561ThrAsn: 2.561 ± 0.805
2.195ThrPro: 2.195 ± 1.808
2.561ThrGln: 2.561 ± 0.202
2.195ThrArg: 2.195 ± 0.602
6.952ThrSer: 6.952 ± 1.606
6.952ThrThr: 6.952 ± 2.209
6.952ThrVal: 6.952 ± 2.812
0.732ThrTrp: 0.732 ± 0.201
2.927ThrTyr: 2.927 ± 0.403
0.0ThrXaa: 0.0 ± 0.0
Val
4.391ValAla: 4.391 ± 0.001
0.732ValCys: 0.732 ± 0.201
6.22ValAsp: 6.22 ± 1.405
5.123ValGlu: 5.123 ± 0.199
3.659ValPhe: 3.659 ± 1.004
4.025ValGly: 4.025 ± 0.2
1.829ValHis: 1.829 ± 0.2
4.757ValIle: 4.757 ± 1.003
5.488ValLys: 5.488 ± 1.81
4.757ValLeu: 4.757 ± 1.003
2.195ValMet: 2.195 ± 0.604
4.391ValAsn: 4.391 ± 0.604
2.927ValPro: 2.927 ± 0.403
2.561ValGln: 2.561 ± 1.607
2.561ValArg: 2.561 ± 0.805
7.318ValSer: 7.318 ± 3.213
5.854ValThr: 5.854 ± 1.606
4.757ValVal: 4.757 ± 2.209
0.732ValTrp: 0.732 ± 0.201
2.561ValTyr: 2.561 ± 0.401
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.366TrpCys: 0.366 ± 0.201
0.366TrpAsp: 0.366 ± 0.201
0.0TrpGlu: 0.0 ± 0.0
1.098TrpPhe: 1.098 ± 0.603
0.0TrpGly: 0.0 ± 0.0
0.366TrpHis: 0.366 ± 0.201
0.732TrpIle: 0.732 ± 0.201
0.0TrpLys: 0.0 ± 0.0
1.098TrpLeu: 1.098 ± 0.0
1.098TrpMet: 1.098 ± 0.0
1.464TrpAsn: 1.464 ± 0.402
0.0TrpPro: 0.0 ± 0.0
0.732TrpGln: 0.732 ± 0.402
0.732TrpArg: 0.732 ± 0.804
0.366TrpSer: 0.366 ± 0.402
1.098TrpThr: 1.098 ± 0.603
0.732TrpVal: 0.732 ± 0.201
0.366TrpTrp: 0.366 ± 0.402
0.732TrpTyr: 0.732 ± 0.201
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.195TyrAla: 2.195 ± 0.001
2.195TyrCys: 2.195 ± 1.207
0.732TyrAsp: 0.732 ± 0.402
2.927TyrGlu: 2.927 ± 1.006
1.464TyrPhe: 1.464 ± 0.201
2.561TyrGly: 2.561 ± 0.401
1.098TyrHis: 1.098 ± 0.0
2.195TyrIle: 2.195 ± 0.001
2.561TyrLys: 2.561 ± 1.607
2.195TyrLeu: 2.195 ± 0.001
0.732TyrMet: 0.732 ± 0.201
1.464TyrAsn: 1.464 ± 0.201
1.464TyrPro: 1.464 ± 0.201
1.829TyrGln: 1.829 ± 0.2
1.464TyrArg: 1.464 ± 1.004
4.757TyrSer: 4.757 ± 0.202
2.927TyrThr: 2.927 ± 0.2
2.195TyrVal: 2.195 ± 0.001
0.366TyrTrp: 0.366 ± 0.201
0.732TyrTyr: 0.732 ± 0.402
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2734 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski