Amino acid dipepetide frequency for Aurantiacibacter luteus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.977AlaAla: 18.977 ± 0.212
1.113AlaCys: 1.113 ± 0.037
8.008AlaAsp: 8.008 ± 0.108
9.028AlaGlu: 9.028 ± 0.131
4.446AlaPhe: 4.446 ± 0.077
11.674AlaGly: 11.674 ± 0.115
2.295AlaHis: 2.295 ± 0.059
6.361AlaIle: 6.361 ± 0.076
3.48AlaLys: 3.48 ± 0.084
14.51AlaLeu: 14.51 ± 0.172
4.318AlaMet: 4.318 ± 0.092
3.28AlaAsn: 3.28 ± 0.068
6.185AlaPro: 6.185 ± 0.116
4.545AlaGln: 4.545 ± 0.08
10.263AlaArg: 10.263 ± 0.155
6.6AlaSer: 6.6 ± 0.096
6.329AlaThr: 6.329 ± 0.101
8.774AlaVal: 8.774 ± 0.113
1.651AlaTrp: 1.651 ± 0.048
2.619AlaTyr: 2.619 ± 0.049
0.0AlaXaa: 0.0 ± 0.0
Cys
1.031CysAla: 1.031 ± 0.039
0.079CysCys: 0.079 ± 0.01
0.583CysAsp: 0.583 ± 0.025
0.493CysGlu: 0.493 ± 0.027
0.263CysPhe: 0.263 ± 0.02
0.9CysGly: 0.9 ± 0.034
0.209CysHis: 0.209 ± 0.016
0.324CysIle: 0.324 ± 0.019
0.155CysLys: 0.155 ± 0.013
0.658CysLeu: 0.658 ± 0.029
0.157CysMet: 0.157 ± 0.013
0.239CysAsn: 0.239 ± 0.018
0.42CysPro: 0.42 ± 0.024
0.216CysGln: 0.216 ± 0.017
0.533CysArg: 0.533 ± 0.029
0.438CysSer: 0.438 ± 0.027
0.37CysThr: 0.37 ± 0.023
0.555CysVal: 0.555 ± 0.026
0.106CysTrp: 0.106 ± 0.012
0.167CysTyr: 0.167 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
8.029AspAla: 8.029 ± 0.109
0.539AspCys: 0.539 ± 0.025
3.502AspAsp: 3.502 ± 0.079
4.271AspGlu: 4.271 ± 0.082
2.463AspPhe: 2.463 ± 0.061
5.856AspGly: 5.856 ± 0.111
1.275AspHis: 1.275 ± 0.044
2.798AspIle: 2.798 ± 0.065
1.526AspLys: 1.526 ± 0.047
6.033AspLeu: 6.033 ± 0.085
1.526AspMet: 1.526 ± 0.044
1.483AspAsn: 1.483 ± 0.051
3.894AspPro: 3.894 ± 0.071
1.612AspGln: 1.612 ± 0.051
4.688AspArg: 4.688 ± 0.078
2.367AspSer: 2.367 ± 0.064
2.978AspThr: 2.978 ± 0.062
4.104AspVal: 4.104 ± 0.082
1.304AspTrp: 1.304 ± 0.044
1.687AspTyr: 1.687 ± 0.052
0.0AspXaa: 0.0 ± 0.0
Glu
8.99GluAla: 8.99 ± 0.141
0.382GluCys: 0.382 ± 0.026
3.634GluAsp: 3.634 ± 0.064
3.879GluGlu: 3.879 ± 0.089
1.736GluPhe: 1.736 ± 0.052
5.527GluGly: 5.527 ± 0.102
1.331GluHis: 1.331 ± 0.037
2.934GluIle: 2.934 ± 0.068
1.841GluLys: 1.841 ± 0.06
5.61GluLeu: 5.61 ± 0.086
1.585GluMet: 1.585 ± 0.046
1.597GluAsn: 1.597 ± 0.044
2.917GluPro: 2.917 ± 0.06
2.325GluGln: 2.325 ± 0.057
5.685GluArg: 5.685 ± 0.09
2.533GluSer: 2.533 ± 0.053
3.307GluThr: 3.307 ± 0.061
4.461GluVal: 4.461 ± 0.081
0.939GluTrp: 0.939 ± 0.032
1.114GluTyr: 1.114 ± 0.037
0.0GluXaa: 0.0 ± 0.0
Phe
5.226PheAla: 5.226 ± 0.082
0.319PheCys: 0.319 ± 0.019
2.877PheAsp: 2.877 ± 0.071
2.176PheGlu: 2.176 ± 0.056
1.27PhePhe: 1.27 ± 0.044
3.574PheGly: 3.574 ± 0.071
0.675PheHis: 0.675 ± 0.028
1.355PheIle: 1.355 ± 0.039
0.7PheLys: 0.7 ± 0.032
2.975PheLeu: 2.975 ± 0.068
0.765PheMet: 0.765 ± 0.03
0.947PheAsn: 0.947 ± 0.038
1.575PhePro: 1.575 ± 0.046
0.902PheGln: 0.902 ± 0.037
2.184PheArg: 2.184 ± 0.054
1.926PheSer: 1.926 ± 0.051
2.11PheThr: 2.11 ± 0.052
2.82PheVal: 2.82 ± 0.065
0.544PheTrp: 0.544 ± 0.027
0.912PheTyr: 0.912 ± 0.034
0.0PheXaa: 0.0 ± 0.0
Gly
10.057GlyAla: 10.057 ± 0.113
0.856GlyCys: 0.856 ± 0.03
5.233GlyAsp: 5.233 ± 0.081
6.353GlyGlu: 6.353 ± 0.097
3.634GlyPhe: 3.634 ± 0.069
8.446GlyGly: 8.446 ± 0.14
1.933GlyHis: 1.933 ± 0.048
4.075GlyIle: 4.075 ± 0.066
2.941GlyLys: 2.941 ± 0.061
8.554GlyLeu: 8.554 ± 0.114
2.577GlyMet: 2.577 ± 0.063
2.479GlyAsn: 2.479 ± 0.068
3.711GlyPro: 3.711 ± 0.072
2.997GlyGln: 2.997 ± 0.057
6.454GlyArg: 6.454 ± 0.089
4.841GlySer: 4.841 ± 0.076
5.09GlyThr: 5.09 ± 0.108
6.293GlyVal: 6.293 ± 0.091
1.695GlyTrp: 1.695 ± 0.053
2.326GlyTyr: 2.326 ± 0.059
0.0GlyXaa: 0.0 ± 0.0
His
2.404HisAla: 2.404 ± 0.057
0.221HisCys: 0.221 ± 0.016
1.211HisAsp: 1.211 ± 0.047
1.133HisGlu: 1.133 ± 0.04
0.832HisPhe: 0.832 ± 0.03
1.895HisGly: 1.895 ± 0.061
0.549HisHis: 0.549 ± 0.026
0.799HisIle: 0.799 ± 0.03
0.447HisLys: 0.447 ± 0.024
1.81HisLeu: 1.81 ± 0.048
0.431HisMet: 0.431 ± 0.023
0.413HisAsn: 0.413 ± 0.027
1.332HisPro: 1.332 ± 0.048
0.513HisGln: 0.513 ± 0.026
1.455HisArg: 1.455 ± 0.047
0.876HisSer: 0.876 ± 0.032
0.826HisThr: 0.826 ± 0.027
1.474HisVal: 1.474 ± 0.039
0.352HisTrp: 0.352 ± 0.022
0.523HisTyr: 0.523 ± 0.025
0.0HisXaa: 0.0 ± 0.0
Ile
7.216IleAla: 7.216 ± 0.108
0.395IleCys: 0.395 ± 0.021
3.631IleAsp: 3.631 ± 0.074
3.414IleGlu: 3.414 ± 0.066
1.372IlePhe: 1.372 ± 0.04
4.638IleGly: 4.638 ± 0.079
0.823IleHis: 0.823 ± 0.032
1.605IleIle: 1.605 ± 0.054
0.984IleLys: 0.984 ± 0.033
3.167IleLeu: 3.167 ± 0.065
0.84IleMet: 0.84 ± 0.029
1.151IleAsn: 1.151 ± 0.04
2.144IlePro: 2.144 ± 0.046
0.939IleGln: 0.939 ± 0.034
2.763IleArg: 2.763 ± 0.066
2.124IleSer: 2.124 ± 0.052
2.294IleThr: 2.294 ± 0.056
3.853IleVal: 3.853 ± 0.068
0.503IleTrp: 0.503 ± 0.022
0.95IleTyr: 0.95 ± 0.034
0.0IleXaa: 0.0 ± 0.0
Lys
3.396LysAla: 3.396 ± 0.085
0.139LysCys: 0.139 ± 0.012
1.435LysAsp: 1.435 ± 0.051
1.09LysGlu: 1.09 ± 0.04
0.697LysPhe: 0.697 ± 0.031
2.235LysGly: 2.235 ± 0.061
0.477LysHis: 0.477 ± 0.026
1.156LysIle: 1.156 ± 0.035
0.978LysLys: 0.978 ± 0.048
2.787LysLeu: 2.787 ± 0.069
0.585LysMet: 0.585 ± 0.03
0.607LysAsn: 0.607 ± 0.031
1.501LysPro: 1.501 ± 0.054
0.721LysGln: 0.721 ± 0.032
2.03LysArg: 2.03 ± 0.059
1.274LysSer: 1.274 ± 0.04
1.42LysThr: 1.42 ± 0.046
1.96LysVal: 1.96 ± 0.058
0.36LysTrp: 0.36 ± 0.021
0.519LysTyr: 0.519 ± 0.027
0.0LysXaa: 0.0 ± 0.0
Leu
15.472LeuAla: 15.472 ± 0.173
0.702LeuCys: 0.702 ± 0.03
6.072LeuAsp: 6.072 ± 0.101
5.487LeuGlu: 5.487 ± 0.089
3.491LeuPhe: 3.491 ± 0.073
8.6LeuGly: 8.6 ± 0.119
1.709LeuHis: 1.709 ± 0.049
3.91LeuIle: 3.91 ± 0.076
2.449LeuLys: 2.449 ± 0.065
9.584LeuLeu: 9.584 ± 0.159
2.178LeuMet: 2.178 ± 0.052
2.06LeuAsn: 2.06 ± 0.047
5.626LeuPro: 5.626 ± 0.087
2.529LeuGln: 2.529 ± 0.059
6.721LeuArg: 6.721 ± 0.111
5.455LeuSer: 5.455 ± 0.084
5.277LeuThr: 5.277 ± 0.078
8.012LeuVal: 8.012 ± 0.113
1.241LeuTrp: 1.241 ± 0.038
1.932LeuTyr: 1.932 ± 0.052
0.0LeuXaa: 0.0 ± 0.0
Met
3.592MetAla: 3.592 ± 0.074
0.17MetCys: 0.17 ± 0.015
1.324MetAsp: 1.324 ± 0.048
1.252MetGlu: 1.252 ± 0.041
0.702MetPhe: 0.702 ± 0.03
2.103MetGly: 2.103 ± 0.048
0.489MetHis: 0.489 ± 0.022
1.184MetIle: 1.184 ± 0.039
0.831MetLys: 0.831 ± 0.031
2.676MetLeu: 2.676 ± 0.055
0.627MetMet: 0.627 ± 0.031
0.669MetAsn: 0.669 ± 0.03
1.478MetPro: 1.478 ± 0.046
0.851MetGln: 0.851 ± 0.035
1.933MetArg: 1.933 ± 0.048
1.35MetSer: 1.35 ± 0.04
1.725MetThr: 1.725 ± 0.045
1.737MetVal: 1.737 ± 0.047
0.26MetTrp: 0.26 ± 0.018
0.304MetTyr: 0.304 ± 0.02
0.0MetXaa: 0.0 ± 0.0
Asn
3.125AsnAla: 3.125 ± 0.069
0.236AsnCys: 0.236 ± 0.019
1.36AsnAsp: 1.36 ± 0.04
1.223AsnGlu: 1.223 ± 0.036
0.884AsnPhe: 0.884 ± 0.035
2.368AsnGly: 2.368 ± 0.068
0.475AsnHis: 0.475 ± 0.02
1.118AsnIle: 1.118 ± 0.04
0.549AsnLys: 0.549 ± 0.031
2.507AsnLeu: 2.507 ± 0.055
0.553AsnMet: 0.553 ± 0.024
0.613AsnAsn: 0.613 ± 0.031
1.82AsnPro: 1.82 ± 0.049
0.709AsnGln: 0.709 ± 0.032
1.82AsnArg: 1.82 ± 0.045
1.137AsnSer: 1.137 ± 0.041
1.234AsnThr: 1.234 ± 0.045
1.94AsnVal: 1.94 ± 0.051
0.382AsnTrp: 0.382 ± 0.025
0.645AsnTyr: 0.645 ± 0.028
0.0AsnXaa: 0.0 ± 0.0
Pro
7.119ProAla: 7.119 ± 0.119
0.323ProCys: 0.323 ± 0.021
3.899ProAsp: 3.899 ± 0.085
3.851ProGlu: 3.851 ± 0.064
1.996ProPhe: 1.996 ± 0.049
4.913ProGly: 4.913 ± 0.075
1.024ProHis: 1.024 ± 0.038
2.17ProIle: 2.17 ± 0.057
1.155ProLys: 1.155 ± 0.041
4.94ProLeu: 4.94 ± 0.07
1.185ProMet: 1.185 ± 0.035
1.112ProAsn: 1.112 ± 0.035
2.789ProPro: 2.789 ± 0.103
1.733ProGln: 1.733 ± 0.044
3.178ProArg: 3.178 ± 0.08
2.544ProSer: 2.544 ± 0.056
2.449ProThr: 2.449 ± 0.059
4.421ProVal: 4.421 ± 0.081
0.725ProTrp: 0.725 ± 0.029
1.113ProTyr: 1.113 ± 0.037
0.0ProXaa: 0.0 ± 0.0
Gln
4.142GlnAla: 4.142 ± 0.085
0.221GlnCys: 0.221 ± 0.017
1.61GlnAsp: 1.61 ± 0.054
1.397GlnGlu: 1.397 ± 0.046
1.142GlnPhe: 1.142 ± 0.041
2.611GlnGly: 2.611 ± 0.054
0.601GlnHis: 0.601 ± 0.029
1.42GlnIle: 1.42 ± 0.037
0.721GlnLys: 0.721 ± 0.029
3.103GlnLeu: 3.103 ± 0.061
0.84GlnMet: 0.84 ± 0.034
0.694GlnAsn: 0.694 ± 0.032
1.834GlnPro: 1.834 ± 0.051
1.256GlnGln: 1.256 ± 0.053
2.574GlnArg: 2.574 ± 0.056
1.607GlnSer: 1.607 ± 0.041
1.527GlnThr: 1.527 ± 0.04
2.532GlnVal: 2.532 ± 0.058
0.413GlnTrp: 0.413 ± 0.024
0.669GlnTyr: 0.669 ± 0.033
0.0GlnXaa: 0.0 ± 0.0
Arg
9.078ArgAla: 9.078 ± 0.132
0.473ArgCys: 0.473 ± 0.025
4.44ArgAsp: 4.44 ± 0.077
4.976ArgGlu: 4.976 ± 0.078
3.067ArgPhe: 3.067 ± 0.051
5.518ArgGly: 5.518 ± 0.086
1.605ArgHis: 1.605 ± 0.049
3.725ArgIle: 3.725 ± 0.062
1.882ArgLys: 1.882 ± 0.058
7.917ArgLeu: 7.917 ± 0.122
2.098ArgMet: 2.098 ± 0.052
1.769ArgAsn: 1.769 ± 0.044
3.514ArgPro: 3.514 ± 0.063
2.609ArgGln: 2.609 ± 0.057
5.709ArgArg: 5.709 ± 0.096
3.414ArgSer: 3.414 ± 0.076
3.325ArgThr: 3.325 ± 0.057
5.171ArgVal: 5.171 ± 0.082
1.209ArgTrp: 1.209 ± 0.041
1.769ArgTyr: 1.769 ± 0.052
0.0ArgXaa: 0.0 ± 0.0
Ser
6.145SerAla: 6.145 ± 0.088
0.383SerCys: 0.383 ± 0.024
3.145SerAsp: 3.145 ± 0.06
2.846SerGlu: 2.846 ± 0.068
1.934SerPhe: 1.934 ± 0.058
5.213SerGly: 5.213 ± 0.072
0.944SerHis: 0.944 ± 0.031
2.204SerIle: 2.204 ± 0.054
1.096SerLys: 1.096 ± 0.037
4.886SerLeu: 4.886 ± 0.083
1.175SerMet: 1.175 ± 0.037
1.326SerAsn: 1.326 ± 0.04
2.761SerPro: 2.761 ± 0.057
1.481SerGln: 1.481 ± 0.046
3.545SerArg: 3.545 ± 0.07
2.545SerSer: 2.545 ± 0.057
2.446SerThr: 2.446 ± 0.053
3.539SerVal: 3.539 ± 0.062
0.677SerTrp: 0.677 ± 0.025
1.252SerTyr: 1.252 ± 0.038
0.0SerXaa: 0.0 ± 0.0
Thr
6.252ThrAla: 6.252 ± 0.101
0.376ThrCys: 0.376 ± 0.023
3.048ThrAsp: 3.048 ± 0.063
2.475ThrGlu: 2.475 ± 0.057
1.978ThrPhe: 1.978 ± 0.051
5.49ThrGly: 5.49 ± 0.083
0.875ThrHis: 0.875 ± 0.033
2.708ThrIle: 2.708 ± 0.066
1.047ThrLys: 1.047 ± 0.04
5.538ThrLeu: 5.538 ± 0.081
1.259ThrMet: 1.259 ± 0.037
1.262ThrAsn: 1.262 ± 0.053
3.2ThrPro: 3.2 ± 0.067
1.414ThrGln: 1.414 ± 0.042
3.551ThrArg: 3.551 ± 0.074
2.547ThrSer: 2.547 ± 0.053
2.673ThrThr: 2.673 ± 0.068
4.203ThrVal: 4.203 ± 0.079
0.641ThrTrp: 0.641 ± 0.029
1.322ThrTyr: 1.322 ± 0.047
0.0ThrXaa: 0.0 ± 0.0
Val
10.03ValAla: 10.03 ± 0.125
0.581ValCys: 0.581 ± 0.025
4.521ValAsp: 4.521 ± 0.08
5.025ValGlu: 5.025 ± 0.073
2.479ValPhe: 2.479 ± 0.059
5.856ValGly: 5.856 ± 0.091
1.35ValHis: 1.35 ± 0.041
3.497ValIle: 3.497 ± 0.068
1.747ValLys: 1.747 ± 0.048
7.297ValLeu: 7.297 ± 0.115
1.789ValMet: 1.789 ± 0.048
1.957ValAsn: 1.957 ± 0.056
4.151ValPro: 4.151 ± 0.073
2.16ValGln: 2.16 ± 0.051
4.966ValArg: 4.966 ± 0.076
3.917ValSer: 3.917 ± 0.06
4.594ValThr: 4.594 ± 0.096
5.844ValVal: 5.844 ± 0.097
0.922ValTrp: 0.922 ± 0.034
1.332ValTyr: 1.332 ± 0.041
0.0ValXaa: 0.0 ± 0.0
Trp
1.405TrpAla: 1.405 ± 0.046
0.157TrpCys: 0.157 ± 0.012
0.822TrpAsp: 0.822 ± 0.035
0.641TrpGlu: 0.641 ± 0.025
0.598TrpPhe: 0.598 ± 0.031
0.98TrpGly: 0.98 ± 0.037
0.385TrpHis: 0.385 ± 0.023
0.652TrpIle: 0.652 ± 0.031
0.388TrpLys: 0.388 ± 0.024
1.864TrpLeu: 1.864 ± 0.055
0.389TrpMet: 0.389 ± 0.023
0.441TrpAsn: 0.441 ± 0.024
0.717TrpPro: 0.717 ± 0.028
0.765TrpGln: 0.765 ± 0.032
1.331TrpArg: 1.331 ± 0.046
0.882TrpSer: 0.882 ± 0.033
0.757TrpThr: 0.757 ± 0.028
0.826TrpVal: 0.826 ± 0.035
0.286TrpTrp: 0.286 ± 0.018
0.293TrpTyr: 0.293 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.773TyrAla: 2.773 ± 0.061
0.23TyrCys: 0.23 ± 0.016
1.579TyrAsp: 1.579 ± 0.048
1.313TyrGlu: 1.313 ± 0.042
0.846TyrPhe: 0.846 ± 0.035
2.146TyrGly: 2.146 ± 0.055
0.473TyrHis: 0.473 ± 0.024
0.811TyrIle: 0.811 ± 0.032
0.451TyrLys: 0.451 ± 0.022
2.092TyrLeu: 2.092 ± 0.053
0.378TyrMet: 0.378 ± 0.025
0.6TyrAsn: 0.6 ± 0.028
1.07TyrPro: 1.07 ± 0.041
0.636TyrGln: 0.636 ± 0.027
1.888TyrArg: 1.888 ± 0.056
1.167TyrSer: 1.167 ± 0.037
1.126TyrThr: 1.126 ± 0.043
1.496TyrVal: 1.496 ± 0.048
0.37TyrTrp: 0.37 ± 0.022
0.615TyrTyr: 0.615 ± 0.03
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2651 proteins (833031 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski