Phytophthora endornavirus 1 (PhEV-1)
Average proteome isoelectric point is 5.6
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|Q53I73|Q53I73_PHEV1 Uncharacterized protein polyprotein OS=Phytophthora endornavirus 1 OX=310750 GN=polyprotein PE=2 SV=1
MM1 pKa = 7.61 SSTISNYY8 pKa = 9.88 QKK10 pKa = 10.3 LQSRR14 pKa = 11.84 KK15 pKa = 6.35 TLRR18 pKa = 11.84 GGRR21 pKa = 11.84 RR22 pKa = 11.84 TGVGGLPVALNQEE35 pKa = 4.4 QILTLRR41 pKa = 11.84 KK42 pKa = 9.62 KK43 pKa = 11.0 LNLKK47 pKa = 6.13 VTKK50 pKa = 10.14 RR51 pKa = 11.84 FNYY54 pKa = 9.91 LKK56 pKa = 10.87 SIDD59 pKa = 3.78 KK60 pKa = 10.33 KK61 pKa = 9.15 YY62 pKa = 11.18 KK63 pKa = 10.69 EE64 pKa = 4.01 MVKK67 pKa = 9.43 TSKK70 pKa = 10.95 YY71 pKa = 9.26 PGRR74 pKa = 11.84 LVPISKK80 pKa = 10.35 ALNKK84 pKa = 10.21 KK85 pKa = 9.8 AMQRR89 pKa = 11.84 MTRR92 pKa = 11.84 NIIIPDD98 pKa = 3.81 CMHH101 pKa = 7.44 PSQLLAVKK109 pKa = 9.91 VAIANNTDD117 pKa = 2.15 KK118 pKa = 11.13 WFITRR123 pKa = 11.84 DD124 pKa = 3.14 AFLEE128 pKa = 4.1 LKK130 pKa = 10.49 NLSEE134 pKa = 4.57 LANGSQQEE142 pKa = 4.02 VRR144 pKa = 11.84 LSVLRR149 pKa = 11.84 SKK151 pKa = 10.73 LYY153 pKa = 10.41 KK154 pKa = 8.31 YY155 pKa = 9.2 TSIGKK160 pKa = 8.84 EE161 pKa = 4.1 VIPGEE166 pKa = 4.03 ANYY169 pKa = 9.85 FRR171 pKa = 11.84 TWFKK175 pKa = 10.37 WLSSNYY181 pKa = 8.53 NNSMYY186 pKa = 10.37 WMWAKK191 pKa = 10.43 YY192 pKa = 7.32 QTAATILCDD201 pKa = 4.78 RR202 pKa = 11.84 IVEE205 pKa = 4.35 TAAGCVMYY213 pKa = 9.98 IDD215 pKa = 5.35 CEE217 pKa = 3.99 PAPAEE222 pKa = 4.21 TVVEE226 pKa = 4.08 CAYY229 pKa = 10.99 CGMLNHH235 pKa = 5.83 MTSADD240 pKa = 3.31 NVMCGSCYY248 pKa = 10.69 GDD250 pKa = 3.48 LEE252 pKa = 4.44 VTIEE256 pKa = 4.08 SAIPGEE262 pKa = 4.14 PIIEE266 pKa = 4.21 LVLNMLQGHH275 pKa = 6.88 FGMAMLEE282 pKa = 3.95 QLSLSNYY289 pKa = 9.82 LDD291 pKa = 3.85 LSALAEE297 pKa = 4.28 SGIGPSIINHH307 pKa = 6.85 DD308 pKa = 4.13 LMIVKK313 pKa = 10.22 QILSRR318 pKa = 11.84 SMNMAVKK325 pKa = 10.41 VPSNLSLKK333 pKa = 10.08 EE334 pKa = 3.95 LSTLRR339 pKa = 11.84 FTLGTDD345 pKa = 3.68 MCCPIHH351 pKa = 6.93 PNTSGARR358 pKa = 11.84 KK359 pKa = 9.82 SSAEE363 pKa = 3.98 VSWVVTQLRR372 pKa = 11.84 QLTSSKK378 pKa = 10.92 GKK380 pKa = 10.31 IIVVDD385 pKa = 3.55 SMNVLQCLEE394 pKa = 4.19 LQDD397 pKa = 4.53 GVIEE401 pKa = 4.3 VVNDD405 pKa = 3.06 IAEE408 pKa = 4.18 ADD410 pKa = 3.82 IAWGQVEE417 pKa = 4.52 HH418 pKa = 6.39 VVIYY422 pKa = 10.27 LPNALEE428 pKa = 4.0 LSCIFSAAPINVCVTTLQLDD448 pKa = 3.85 PKK450 pKa = 9.74 DD451 pKa = 3.99 PEE453 pKa = 4.73 MLTEE457 pKa = 4.53 WDD459 pKa = 3.65 TQQIGEE465 pKa = 4.62 TVWWSPVYY473 pKa = 11.0 SNLAASQDD481 pKa = 3.83 VGDD484 pKa = 3.95 VTLLLGDD491 pKa = 4.41 HH492 pKa = 5.66 YY493 pKa = 10.13 TVNNHH498 pKa = 4.72 NTILNASKK506 pKa = 10.27 INKK509 pKa = 8.63 IGYY512 pKa = 6.9 FTRR515 pKa = 11.84 CEE517 pKa = 3.61 IHH519 pKa = 6.89 RR520 pKa = 11.84 SEE522 pKa = 4.3 GLPVEE527 pKa = 4.72 LLTDD531 pKa = 4.04 VIGSLIEE538 pKa = 3.8 EE539 pKa = 4.04 EE540 pKa = 4.8 RR541 pKa = 11.84 EE542 pKa = 4.05 FKK544 pKa = 10.8 IPTVDD549 pKa = 2.88 MDD551 pKa = 4.23 ALVTRR556 pKa = 11.84 FGGAVIKK563 pKa = 9.86 TKK565 pKa = 10.27 TIALDD570 pKa = 3.77 RR571 pKa = 11.84 VFLRR575 pKa = 11.84 YY576 pKa = 9.68 LLNKK580 pKa = 9.06 TMLGNMGYY588 pKa = 9.03 NQTVEE593 pKa = 4.23 YY594 pKa = 10.09 AISLCYY600 pKa = 9.99 SRR602 pKa = 11.84 YY603 pKa = 9.96 VMDD606 pKa = 3.73 GRR608 pKa = 11.84 EE609 pKa = 4.11 MNFSRR614 pKa = 11.84 ISAEE618 pKa = 3.75 SCRR621 pKa = 11.84 DD622 pKa = 3.33 HH623 pKa = 8.37 AYY625 pKa = 9.75 VAVMXTGLTSTEE637 pKa = 4.18 FKK639 pKa = 10.5 TGEE642 pKa = 4.3 TVLGPNNGAQQVINVLSLGAMQGLWAVGLDD672 pKa = 3.62 LCEE675 pKa = 4.01 QLLPEE680 pKa = 5.61 PISEE684 pKa = 4.18 AVKK687 pKa = 9.2 KK688 pKa = 9.14 TITWLKK694 pKa = 9.86 QGNTSDD700 pKa = 3.89 YY701 pKa = 8.81 QTTDD705 pKa = 1.75 IWEE708 pKa = 4.22 KK709 pKa = 10.76 LRR711 pKa = 11.84 DD712 pKa = 3.5 WVYY715 pKa = 11.38 GNTFDD720 pKa = 3.45 SCKK723 pKa = 10.7 YY724 pKa = 9.71 YY725 pKa = 11.17 VEE727 pKa = 4.63 TKK729 pKa = 9.09 WKK731 pKa = 8.75 YY732 pKa = 9.53 QEE734 pKa = 4.57 PEE736 pKa = 4.41 SNCDD740 pKa = 3.13 HH741 pKa = 7.14 HH742 pKa = 9.33 SPDD745 pKa = 4.82 CDD747 pKa = 3.77 DD748 pKa = 4.0 EE749 pKa = 4.58 QVGVDD754 pKa = 3.74 DD755 pKa = 5.93 QDD757 pKa = 3.7 TLRR760 pKa = 11.84 CLCCLLFKK768 pKa = 10.84 ASPVTKK774 pKa = 10.32 LCKK777 pKa = 10.29 CCTLSSKK784 pKa = 10.75 CNHH787 pKa = 6.48 KK788 pKa = 10.52 CSHH791 pKa = 6.17 TCTSEE796 pKa = 4.38 LDD798 pKa = 3.81 HH799 pKa = 6.98 ICNKK803 pKa = 9.6 KK804 pKa = 10.3 CKK806 pKa = 8.63 HH807 pKa = 5.34 QKK809 pKa = 9.49 ILCDD813 pKa = 3.47 CCGVPTCFDD822 pKa = 3.85 EE823 pKa = 6.36 CPVCQTPVTWVLPISLAAKK842 pKa = 9.23 EE843 pKa = 4.04 ISNASRR849 pKa = 11.84 RR850 pKa = 11.84 NRR852 pKa = 11.84 PVHH855 pKa = 4.55 MAKK858 pKa = 9.8 PRR860 pKa = 11.84 KK861 pKa = 8.87 IDD863 pKa = 3.32 RR864 pKa = 11.84 EE865 pKa = 4.07 KK866 pKa = 10.79 IEE868 pKa = 4.32 DD869 pKa = 3.43 QEE871 pKa = 4.42 FTVKK875 pKa = 10.66 GEE877 pKa = 3.98 PVSRR881 pKa = 11.84 VPVFKK886 pKa = 9.92 THH888 pKa = 6.3 GLTLGLTGCNIQEE901 pKa = 4.12 VMEE904 pKa = 4.27 NQAEE908 pKa = 4.2 IQAKK912 pKa = 9.67 VNEE915 pKa = 4.49 LKK917 pKa = 11.17 LEE919 pKa = 4.21 DD920 pKa = 3.93 VEE922 pKa = 6.0 VYY924 pKa = 10.81 DD925 pKa = 4.84 PDD927 pKa = 3.81 TLEE930 pKa = 4.68 SIGLFLLIDD939 pKa = 3.5 HH940 pKa = 6.65 TLISEE945 pKa = 4.01 PAKK948 pKa = 10.43 PGEE951 pKa = 4.15 HH952 pKa = 6.51 TISEE956 pKa = 4.36 LVEE959 pKa = 3.71 EE960 pKa = 4.61 AEE962 pKa = 4.1 QRR964 pKa = 11.84 NASTSVDD971 pKa = 3.45 TTPRR975 pKa = 11.84 EE976 pKa = 4.31 HH977 pKa = 6.45 QDD979 pKa = 2.93 KK980 pKa = 10.22 PVALDD985 pKa = 3.58 VPADD989 pKa = 3.86 KK990 pKa = 10.59 QSHH993 pKa = 6.75 DD994 pKa = 4.3 RR995 pKa = 11.84 LSMLAPVVRR1004 pKa = 11.84 RR1005 pKa = 11.84 ACLNGLMKK1013 pKa = 10.61 NWGEE1017 pKa = 3.83 VQPYY1021 pKa = 10.03 FKK1023 pKa = 8.81 TTDD1026 pKa = 3.29 ADD1028 pKa = 3.94 EE1029 pKa = 5.44 AGTTQLVLLAEE1040 pKa = 4.74 GFSSYY1045 pKa = 7.41 VTNDD1049 pKa = 2.69 WLAVVATHH1057 pKa = 7.25 SISAEE1062 pKa = 3.89 DD1063 pKa = 3.8 NLCGFHH1069 pKa = 7.12 ALNLGFEE1076 pKa = 4.59 GASLRR1081 pKa = 11.84 RR1082 pKa = 11.84 LRR1084 pKa = 11.84 EE1085 pKa = 3.69 VSKK1088 pKa = 11.0 KK1089 pKa = 10.63 DD1090 pKa = 3.13 DD1091 pKa = 3.46 WFEE1094 pKa = 3.89 LTDD1097 pKa = 3.56 LVNYY1101 pKa = 8.86 MRR1103 pKa = 11.84 EE1104 pKa = 3.82 EE1105 pKa = 4.06 DD1106 pKa = 3.89 RR1107 pKa = 11.84 NLLVMKK1113 pKa = 10.54 DD1114 pKa = 3.77 EE1115 pKa = 4.35 MVDD1118 pKa = 3.4 VYY1120 pKa = 11.29 TFDD1123 pKa = 4.64 PYY1125 pKa = 11.09 NSVYY1129 pKa = 10.76 VSVEE1133 pKa = 3.95 HH1134 pKa = 6.43 TGSTSSGHH1142 pKa = 5.98 WSPISMVQIKK1152 pKa = 8.61 PAPSLPNWTGVTDD1165 pKa = 4.56 RR1166 pKa = 11.84 NTMSQILLSWGLSVDD1181 pKa = 3.77 TEE1183 pKa = 4.18 FDD1185 pKa = 3.82 DD1186 pKa = 5.91 LSVSQRR1192 pKa = 11.84 ITYY1195 pKa = 10.14 SWMQYY1200 pKa = 8.86 NEE1202 pKa = 3.84 EE1203 pKa = 4.13 VGRR1206 pKa = 11.84 SKK1208 pKa = 11.17 AIVSQTLSLSSEE1220 pKa = 3.93 NGVGYY1225 pKa = 9.91 LHH1227 pKa = 7.37 SGTNTKK1233 pKa = 10.57 NDD1235 pKa = 3.05 IRR1237 pKa = 11.84 SGEE1240 pKa = 4.15 VFLEE1244 pKa = 4.28 IPQQYY1249 pKa = 8.49 VPSMSMLNSSWSLVQNSFEE1268 pKa = 4.28 YY1269 pKa = 9.98 NQPHH1273 pKa = 6.74 SYY1275 pKa = 11.18 SDD1277 pKa = 4.2 TIPLNCSQRR1286 pKa = 11.84 LVQEE1290 pKa = 3.69 VRR1292 pKa = 11.84 EE1293 pKa = 4.07 QIKK1296 pKa = 8.49 TLVQLGFTLDD1306 pKa = 3.33 NYY1308 pKa = 10.83 LPEE1311 pKa = 4.96 IPPGYY1316 pKa = 10.48 YY1317 pKa = 9.99 NLHH1320 pKa = 5.4 QKK1322 pKa = 10.03 GRR1324 pKa = 11.84 AQTISEE1330 pKa = 4.22 GVVRR1334 pKa = 11.84 CRR1336 pKa = 11.84 LTKK1339 pKa = 10.6 EE1340 pKa = 3.95 NIKK1343 pKa = 9.77 TGDD1346 pKa = 3.71 SILVVVSGKK1355 pKa = 10.23 GYY1357 pKa = 7.94 SVRR1360 pKa = 11.84 RR1361 pKa = 11.84 ITRR1364 pKa = 11.84 EE1365 pKa = 3.85 GAWMIFPFVTTQRR1378 pKa = 11.84 RR1379 pKa = 11.84 TTIKK1383 pKa = 10.06 FLNPRR1388 pKa = 11.84 SSCTSTLLRR1397 pKa = 11.84 LQALLQTNPDD1407 pKa = 3.37 TSRR1410 pKa = 11.84 TLQLLQASEE1419 pKa = 4.42 CTLAVPGWGKK1429 pKa = 7.46 STKK1432 pKa = 9.48 IVKK1435 pKa = 9.97 EE1436 pKa = 3.82 FDD1438 pKa = 2.97 TDD1440 pKa = 3.77 TTVTCVTSEE1449 pKa = 3.9 AVKK1452 pKa = 10.88 NLVAMGLPRR1461 pKa = 11.84 NKK1463 pKa = 8.59 VTSVEE1468 pKa = 4.02 RR1469 pKa = 11.84 AVEE1472 pKa = 4.34 SKK1474 pKa = 10.07 IHH1476 pKa = 5.1 TKK1478 pKa = 10.41 KK1479 pKa = 10.69 LAIDD1483 pKa = 3.6 EE1484 pKa = 4.38 CTQVDD1489 pKa = 3.82 WLMVHH1494 pKa = 6.09 MMCGDD1499 pKa = 3.41 EE1500 pKa = 4.64 VEE1502 pKa = 4.97 IITLAGDD1509 pKa = 4.01 SFQIGAVDD1517 pKa = 4.98 FSASTGEE1524 pKa = 4.14 RR1525 pKa = 11.84 TITSCNMFSLHH1536 pKa = 6.13 QNTYY1540 pKa = 9.59 NNSHH1544 pKa = 6.97 RR1545 pKa = 11.84 FGQPLCSQLTVLNPRR1560 pKa = 11.84 LTTDD1564 pKa = 3.54 ALHH1567 pKa = 4.73 QTSYY1571 pKa = 11.13 SVHH1574 pKa = 5.99 NLSSLDD1580 pKa = 3.87 LNVLGSVIAQEE1591 pKa = 4.17 RR1592 pKa = 11.84 PGVILTFHH1600 pKa = 6.95 QITKK1604 pKa = 10.04 SQIQRR1609 pKa = 11.84 AFGRR1613 pKa = 11.84 TIKK1616 pKa = 10.04 TSLTTGDD1623 pKa = 3.44 VKK1625 pKa = 10.1 TVHH1628 pKa = 6.68 SYY1630 pKa = 9.86 QGKK1633 pKa = 7.87 EE1634 pKa = 3.77 SSRR1637 pKa = 11.84 VMVIQDD1643 pKa = 3.8 FLSPAGVHH1651 pKa = 4.9 TDD1653 pKa = 2.72 RR1654 pKa = 11.84 RR1655 pKa = 11.84 YY1656 pKa = 11.24 LMSAASRR1663 pKa = 11.84 ASNHH1667 pKa = 6.41 LIWVTIQSPINSLVLSDD1684 pKa = 4.09 HH1685 pKa = 6.78 LKK1687 pKa = 9.97 TNILVGGHH1695 pKa = 6.82 LSDD1698 pKa = 5.52 IIDD1701 pKa = 3.52 NTVITLCNRR1710 pKa = 11.84 FKK1712 pKa = 11.26 FEE1714 pKa = 4.03 MSLEE1718 pKa = 4.07 TMRR1721 pKa = 11.84 NVVEE1725 pKa = 4.14 YY1726 pKa = 10.98 LFGEE1730 pKa = 4.59 YY1731 pKa = 10.33 EE1732 pKa = 4.24 STHH1735 pKa = 7.13 SDD1737 pKa = 3.62 EE1738 pKa = 4.42 ITLKK1742 pKa = 9.52 TIHH1745 pKa = 6.15 ITGPTEE1751 pKa = 3.55 NEE1753 pKa = 3.92 YY1754 pKa = 10.53 QRR1756 pKa = 11.84 GYY1758 pKa = 10.76 IKK1760 pKa = 10.67 FSQPEE1765 pKa = 4.05 EE1766 pKa = 3.77 EE1767 pKa = 4.11 FLRR1770 pKa = 11.84 RR1771 pKa = 11.84 GRR1773 pKa = 11.84 TYY1775 pKa = 11.26 LVTKK1779 pKa = 9.73 PNLGSPSEE1787 pKa = 4.17 EE1788 pKa = 4.07 PEE1790 pKa = 4.02 VVYY1793 pKa = 10.42 IAEE1796 pKa = 4.09 DD1797 pKa = 3.36 WKK1799 pKa = 10.93 PEE1801 pKa = 3.8 GKK1803 pKa = 9.16 IDD1805 pKa = 4.65 EE1806 pKa = 4.57 RR1807 pKa = 11.84 YY1808 pKa = 9.89 EE1809 pKa = 4.1 LNDD1812 pKa = 3.44 YY1813 pKa = 10.69 AVSNQKK1819 pKa = 7.82 TQVVFGTKK1827 pKa = 9.65 RR1828 pKa = 11.84 ALSTLILPMSINTAGWKK1845 pKa = 8.03 ITLSKK1850 pKa = 10.96 QEE1852 pKa = 4.12 ANVLVTIEE1860 pKa = 4.75 KK1861 pKa = 10.33 YY1862 pKa = 10.87 GKK1864 pKa = 7.55 TLNFIWDD1871 pKa = 3.77 NQLGGVDD1878 pKa = 4.03 LTNHH1882 pKa = 6.96 KK1883 pKa = 10.1 ALQVGLRR1890 pKa = 11.84 LLINTGLLEE1899 pKa = 4.18 RR1900 pKa = 11.84 VLPEE1904 pKa = 3.8 EE1905 pKa = 4.03 LHH1907 pKa = 5.93 NLNLFEE1913 pKa = 4.48 LTLNEE1918 pKa = 4.21 DD1919 pKa = 3.32 RR1920 pKa = 11.84 VMSNAEE1926 pKa = 3.91 LEE1928 pKa = 4.76 EE1929 pKa = 4.09 IAEE1932 pKa = 4.36 MGSVIHH1938 pKa = 6.55 MDD1940 pKa = 3.0 EE1941 pKa = 4.9 LMDD1944 pKa = 4.25 SEE1946 pKa = 6.25 AIMEE1950 pKa = 4.32 PSVRR1954 pKa = 11.84 QGWTHH1959 pKa = 7.72 LINITNGRR1967 pKa = 11.84 LSSEE1971 pKa = 3.98 IQQEE1975 pKa = 4.41 LIVEE1979 pKa = 4.5 SKK1981 pKa = 10.47 NAPNEE1986 pKa = 3.75 SFYY1989 pKa = 9.25 THH1991 pKa = 6.12 KK1992 pKa = 9.86 TGMTLVNYY2000 pKa = 10.35 SRR2002 pKa = 11.84 LSKK2005 pKa = 10.69 LADD2008 pKa = 3.28 AARR2011 pKa = 11.84 RR2012 pKa = 11.84 TSLEE2016 pKa = 4.01 EE2017 pKa = 3.8 LPLPLRR2023 pKa = 11.84 TPFGWVDD2030 pKa = 3.31 VKK2032 pKa = 10.95 RR2033 pKa = 11.84 HH2034 pKa = 5.72 NGCNPCAGISLRR2046 pKa = 11.84 HH2047 pKa = 6.16 HH2048 pKa = 6.87 DD2049 pKa = 4.32 SWWLIDD2055 pKa = 3.27 NDD2057 pKa = 4.08 YY2058 pKa = 10.31 YY2059 pKa = 11.27 RR2060 pKa = 11.84 KK2061 pKa = 10.08 GSRR2064 pKa = 11.84 RR2065 pKa = 11.84 VQFNEE2070 pKa = 3.18 EE2071 pKa = 4.06 STRR2074 pKa = 11.84 DD2075 pKa = 3.27 EE2076 pKa = 4.57 AIIYY2080 pKa = 7.66 VLKK2083 pKa = 10.67 GLQLEE2088 pKa = 4.55 HH2089 pKa = 6.37 TLEE2092 pKa = 4.53 DD2093 pKa = 3.46 VVDD2096 pKa = 4.27 PQEE2099 pKa = 4.17 SSHH2102 pKa = 7.14 PFFCVDD2108 pKa = 3.52 GPGHH2112 pKa = 6.04 EE2113 pKa = 4.56 VWCSNHH2119 pKa = 6.13 EE2120 pKa = 4.2 SLDD2123 pKa = 3.77 FCDD2126 pKa = 3.62 TLMDD2130 pKa = 5.68 RR2131 pKa = 11.84 ISCFKK2136 pKa = 10.3 TYY2138 pKa = 10.21 TEE2140 pKa = 4.75 SKK2142 pKa = 10.68 FEE2144 pKa = 4.15 YY2145 pKa = 10.52 KK2146 pKa = 10.68 DD2147 pKa = 3.4 FTEE2150 pKa = 5.8 NNLTWLQDD2158 pKa = 3.42 VADD2161 pKa = 3.87 KK2162 pKa = 11.12 MEE2164 pKa = 4.0 VFGMYY2169 pKa = 10.37 NITKK2173 pKa = 10.15 PGGDD2177 pKa = 4.28 KK2178 pKa = 10.41 NSKK2181 pKa = 8.85 WNEE2184 pKa = 3.71 SLLQVLNADD2193 pKa = 3.94 GSRR2196 pKa = 11.84 FFVLYY2201 pKa = 8.71 WDD2203 pKa = 3.66 SVFYY2207 pKa = 11.14 YY2208 pKa = 10.47 VDD2210 pKa = 3.75 CDD2212 pKa = 3.66 NDD2214 pKa = 3.56 DD2215 pKa = 4.67 GYY2217 pKa = 10.79 IQQFHH2222 pKa = 6.11 SWVKK2226 pKa = 9.67 VDD2228 pKa = 4.33 LVEE2231 pKa = 4.21 MANKK2235 pKa = 9.83 LFEE2238 pKa = 4.67 VGLEE2242 pKa = 3.94 ARR2244 pKa = 11.84 RR2245 pKa = 11.84 SRR2247 pKa = 11.84 LSTLLLSARR2256 pKa = 11.84 DD2257 pKa = 3.75 TVFGAGVNEE2266 pKa = 5.08 DD2267 pKa = 4.21 GLILDD2272 pKa = 4.98 LDD2274 pKa = 3.43 QHH2276 pKa = 6.53 KK2277 pKa = 10.35 FNKK2280 pKa = 8.01 TAVYY2284 pKa = 9.04 NHH2286 pKa = 6.77 LVQRR2290 pKa = 11.84 MGEE2293 pKa = 4.13 MKK2295 pKa = 10.48 LKK2297 pKa = 10.52 QSALSRR2303 pKa = 11.84 RR2304 pKa = 11.84 PFFHH2308 pKa = 6.71 GKK2310 pKa = 9.03 IAIEE2314 pKa = 3.93 TLKK2317 pKa = 10.96 NQVKK2321 pKa = 6.85 TTLRR2325 pKa = 11.84 GGVVEE2330 pKa = 4.71 EE2331 pKa = 4.98 CPICTGSSVGSEE2343 pKa = 4.09 LVTLIIAHH2351 pKa = 5.89 STDD2354 pKa = 3.31 EE2355 pKa = 4.46 PTTLMLNNPQLLLSNSLWHH2374 pKa = 6.21 HH2375 pKa = 5.96 KK2376 pKa = 9.97 VRR2378 pKa = 11.84 SSEE2381 pKa = 3.79 EE2382 pKa = 3.93 SLFNTTFPSVRR2393 pKa = 11.84 ATFSRR2398 pKa = 11.84 HH2399 pKa = 4.04 ANKK2402 pKa = 9.9 VLGKK2406 pKa = 8.5 ITHH2409 pKa = 5.43 SMKK2412 pKa = 10.28 KK2413 pKa = 9.47 YY2414 pKa = 11.22 AMGEE2418 pKa = 4.07 DD2419 pKa = 3.73 LKK2421 pKa = 11.48 SAGRR2425 pKa = 11.84 LLAASNVLKK2434 pKa = 10.54 KK2435 pKa = 10.74 ASNSEE2440 pKa = 3.77 RR2441 pKa = 11.84 GFEE2444 pKa = 4.34 VFEE2447 pKa = 5.06 HH2448 pKa = 6.23 PTNTCDD2454 pKa = 3.62 NLIVGPLLLAEE2465 pKa = 4.82 PDD2467 pKa = 3.59 SLAEE2471 pKa = 3.42 IWGNEE2476 pKa = 4.07 RR2477 pKa = 11.84 IQVTIIVPAVINSHH2491 pKa = 5.07 SPWYY2495 pKa = 9.96 KK2496 pKa = 10.19 VNSTGGNIQIMEE2508 pKa = 4.74 CGSGLTVKK2516 pKa = 9.99 IRR2518 pKa = 11.84 SEE2520 pKa = 4.0 IYY2522 pKa = 10.38 NSVLNKK2528 pKa = 10.18 PNLTLFGHH2536 pKa = 5.63 TRR2538 pKa = 11.84 CTEE2541 pKa = 4.02 VVGTLFDD2548 pKa = 3.86 YY2549 pKa = 11.22 LIVNTRR2555 pKa = 11.84 GASEE2559 pKa = 4.2 ARR2561 pKa = 11.84 PQKK2564 pKa = 10.03 VWLRR2568 pKa = 11.84 HH2569 pKa = 5.42 PLHH2572 pKa = 6.55 EE2573 pKa = 4.65 VIKK2576 pKa = 10.87 VPILSVNLGEE2586 pKa = 5.78 DD2587 pKa = 3.19 IANKK2591 pKa = 10.43 SIVKK2595 pKa = 9.09 WKK2597 pKa = 10.1 EE2598 pKa = 3.62 FRR2600 pKa = 11.84 CDD2602 pKa = 3.34 PVVLRR2607 pKa = 11.84 RR2608 pKa = 11.84 LEE2610 pKa = 3.98 LRR2612 pKa = 11.84 VNRR2615 pKa = 11.84 PGTNFKK2621 pKa = 10.38 DD2622 pKa = 3.14 LCEE2625 pKa = 4.01 YY2626 pKa = 11.14 ARR2628 pKa = 11.84 TLLHH2632 pKa = 5.86 TRR2634 pKa = 11.84 DD2635 pKa = 3.69 YY2636 pKa = 10.83 TRR2638 pKa = 11.84 LGSWDD2643 pKa = 3.77 TVKK2646 pKa = 10.95 LDD2648 pKa = 3.99 DD2649 pKa = 6.04 LDD2651 pKa = 4.15 MLSHH2655 pKa = 6.51 CQYY2658 pKa = 11.49 AYY2660 pKa = 10.89 YY2661 pKa = 10.37 HH2662 pKa = 6.43 NKK2664 pKa = 10.06 LGNKK2668 pKa = 9.59 SISQMIEE2675 pKa = 3.6 LLNVFDD2681 pKa = 5.07 QSGKK2685 pKa = 10.38 NIPFYY2690 pKa = 11.26 SWLKK2694 pKa = 9.79 GLGVSKK2700 pKa = 10.65 LLDD2703 pKa = 3.54 VTYY2706 pKa = 9.62 STYY2709 pKa = 11.13 AGVMRR2714 pKa = 11.84 DD2715 pKa = 3.18 TGLDD2719 pKa = 3.28 LGLSQTLMEE2728 pKa = 4.38 FCGFIDD2734 pKa = 3.92 EE2735 pKa = 4.69 LVKK2738 pKa = 10.94 NDD2740 pKa = 3.52 TVKK2743 pKa = 11.14 NSVVEE2748 pKa = 3.77 LWNNYY2753 pKa = 7.94 EE2754 pKa = 3.46 PTMYY2758 pKa = 9.88 KK2759 pKa = 9.84 RR2760 pKa = 11.84 HH2761 pKa = 5.5 VSFITWRR2768 pKa = 11.84 AQPTATGEE2776 pKa = 4.24 VGRR2779 pKa = 11.84 LAYY2782 pKa = 10.28 RR2783 pKa = 11.84 LLKK2786 pKa = 10.0 EE2787 pKa = 5.11 FIWEE2791 pKa = 3.91 PHH2793 pKa = 5.73 FEE2795 pKa = 4.65 GDD2797 pKa = 4.54 DD2798 pKa = 3.65 VLRR2801 pKa = 11.84 DD2802 pKa = 4.14 LIPRR2806 pKa = 11.84 GAKK2809 pKa = 10.05 DD2810 pKa = 3.47 DD2811 pKa = 4.11 GKK2813 pKa = 10.98 SEE2815 pKa = 4.03 NSHH2818 pKa = 5.26 TEE2820 pKa = 3.34 EE2821 pKa = 5.53 DD2822 pKa = 4.34 FEE2824 pKa = 5.24 QEE2826 pKa = 3.94 HH2827 pKa = 7.0 SDD2829 pKa = 3.56 FKK2831 pKa = 11.16 HH2832 pKa = 6.94 AVFTSQGTRR2841 pKa = 11.84 GDD2843 pKa = 3.59 VEE2845 pKa = 4.18 PVVKK2849 pKa = 10.28 FINKK2853 pKa = 8.99 IKK2855 pKa = 10.42 HH2856 pKa = 5.92 GYY2858 pKa = 10.17 DD2859 pKa = 3.66 LVTLVCNQGNGEE2871 pKa = 4.21 GVQFPDD2877 pKa = 5.02 DD2878 pKa = 3.48 IRR2880 pKa = 11.84 VVYY2883 pKa = 10.55 IDD2885 pKa = 3.68 MDD2887 pKa = 4.04 GSKK2890 pKa = 10.45 LATLASVGTGEE2901 pKa = 4.36 GLAEE2905 pKa = 4.17 VLSKK2909 pKa = 11.02 LCEE2912 pKa = 4.24 FEE2914 pKa = 5.03 GSMRR2918 pKa = 11.84 DD2919 pKa = 3.5 TLEE2922 pKa = 4.42 KK2923 pKa = 10.58 LLSGPPVTTVYY2934 pKa = 9.52 ATSNCHH2940 pKa = 6.51 LGYY2943 pKa = 8.68 XLADD2947 pKa = 3.95 LVQCKK2952 pKa = 9.63 LVEE2955 pKa = 4.17 LQLFPWPFNPTTKK2968 pKa = 10.4 LEE2970 pKa = 4.11 KK2971 pKa = 10.22 FVAGVTEE2978 pKa = 4.37 RR2979 pKa = 11.84 VLTTTVDD2986 pKa = 3.2 TSGLNRR2992 pKa = 11.84 VKK2994 pKa = 10.05 KK2995 pKa = 8.83 TRR2997 pKa = 11.84 QQHH3000 pKa = 4.95 KK3001 pKa = 9.76 CLLLFAPIVLKK3012 pKa = 10.9 DD3013 pKa = 3.51 IDD3015 pKa = 3.8 HH3016 pKa = 6.79 HH3017 pKa = 7.39 FSDD3020 pKa = 4.96 DD3021 pKa = 3.65 LKK3023 pKa = 11.09 LVKK3026 pKa = 9.72 IDD3028 pKa = 4.03 CSVLKK3033 pKa = 9.05 PTGVKK3038 pKa = 10.1 KK3039 pKa = 10.14 EE3040 pKa = 4.0 ALVVTMGSLVGAGAIARR3057 pKa = 11.84 YY3058 pKa = 8.9 KK3059 pKa = 10.96 ASLQWATKK3067 pKa = 9.11 MKK3069 pKa = 10.26 FSHH3072 pKa = 6.81 IYY3074 pKa = 10.31 LVGNQFRR3081 pKa = 11.84 ADD3083 pKa = 3.8 YY3084 pKa = 9.08 MCDD3087 pKa = 3.05 ASAVLSPTIKK3097 pKa = 9.96 HH3098 pKa = 6.17 LNRR3101 pKa = 11.84 EE3102 pKa = 4.21 GVVVEE3107 pKa = 4.06 IEE3109 pKa = 4.18 SYY3111 pKa = 10.61 LPYY3114 pKa = 10.67 VEE3116 pKa = 5.19 ICSKK3120 pKa = 10.22 DD3121 pKa = 3.67 TICIHH3126 pKa = 6.57 HH3127 pKa = 6.97 GGAGTTNWFMRR3138 pKa = 11.84 LSMRR3142 pKa = 11.84 QIILPLFNDD3151 pKa = 2.9 QWIWANCVSKK3161 pKa = 10.76 LGCAITASPITLPHH3175 pKa = 5.56 ITEE3178 pKa = 4.55 KK3179 pKa = 10.7 EE3180 pKa = 4.0 LSKK3183 pKa = 10.58 LTGKK3187 pKa = 10.09 SGSWSFEE3194 pKa = 3.33 NRR3196 pKa = 11.84 QLQGAHH3202 pKa = 7.5 GINSSRR3208 pKa = 11.84 IPDD3211 pKa = 3.46 WTKK3214 pKa = 10.74 SEE3216 pKa = 4.04 PTEE3219 pKa = 3.67 RR3220 pKa = 11.84 GYY3222 pKa = 10.72 INMLPYY3228 pKa = 10.55 LKK3230 pKa = 10.2 EE3231 pKa = 4.11 GVMSAANDD3239 pKa = 3.44 VSIKK3243 pKa = 9.86 MMNFGPLQLANEE3255 pKa = 4.28 ICALFQLADD3264 pKa = 3.82 SAFDD3268 pKa = 3.22 WHH3270 pKa = 6.82 EE3271 pKa = 4.21 KK3272 pKa = 10.61 DD3273 pKa = 3.47 NSSSGEE3279 pKa = 3.97 EE3280 pKa = 3.94 VDD3282 pKa = 5.01 PEE3284 pKa = 4.59 DD3285 pKa = 4.01 VMQEE3289 pKa = 3.78 EE3290 pKa = 5.16 GEE3292 pKa = 4.36 EE3293 pKa = 4.09 VVPDD3297 pKa = 4.25 LEE3299 pKa = 4.8 SEE3301 pKa = 4.2 EE3302 pKa = 4.24 SDD3304 pKa = 3.81 SYY3306 pKa = 11.86 VSANPEE3312 pKa = 3.31 IAASHH3317 pKa = 4.67 TTKK3320 pKa = 10.49 EE3321 pKa = 4.33 LEE3323 pKa = 4.11 EE3324 pKa = 4.45 SASQLAEE3331 pKa = 3.8 QRR3333 pKa = 11.84 SLASHH3338 pKa = 7.21 RR3339 pKa = 11.84 IEE3341 pKa = 4.7 VGDD3344 pKa = 4.32 SKK3346 pKa = 10.78 PSQASTPCVDD3356 pKa = 3.55 LVVYY3360 pKa = 7.1 QTPVVAYY3367 pKa = 10.3 SNLATEE3373 pKa = 4.7 TSTDD3377 pKa = 3.77 YY3378 pKa = 11.49 PEE3380 pKa = 4.5 MEE3382 pKa = 3.87 PTVLNEE3388 pKa = 3.98 LEE3390 pKa = 4.49 LEE3392 pKa = 4.09 RR3393 pKa = 11.84 SHH3395 pKa = 7.6 AYY3397 pKa = 10.04 RR3398 pKa = 11.84 QDD3400 pKa = 3.41 DD3401 pKa = 3.99 RR3402 pKa = 11.84 EE3403 pKa = 4.33 GTLISSLSKK3412 pKa = 10.6 PPASISNVINWRR3424 pKa = 11.84 SLVNVEE3430 pKa = 5.63 DD3431 pKa = 4.15 SRR3433 pKa = 11.84 CEE3435 pKa = 3.72 ANQICDD3441 pKa = 4.12 TIDD3444 pKa = 3.23 LATNMDD3450 pKa = 4.72 DD3451 pKa = 5.09 SPLTTTTLEE3460 pKa = 4.26 NYY3462 pKa = 7.58 HH3463 pKa = 5.68 TVYY3466 pKa = 10.92 DD3467 pKa = 4.62 PGHH3470 pKa = 6.52 NSPGTCVFDD3479 pKa = 3.85 CLSWLFPNDD3488 pKa = 3.24 KK3489 pKa = 10.66 GDD3491 pKa = 5.04 VVIQWASMLGCRR3503 pKa = 11.84 SWATKK3508 pKa = 10.35 KK3509 pKa = 10.82 DD3510 pKa = 3.29 IIVFTNLIGVSLLLRR3525 pKa = 11.84 QEE3527 pKa = 4.29 EE3528 pKa = 4.26 KK3529 pKa = 10.27 TEE3531 pKa = 3.98 LFGRR3535 pKa = 11.84 QSLSLICLNLVEE3547 pKa = 4.78 RR3548 pKa = 11.84 GGIGHH3553 pKa = 6.51 CTVIHH3558 pKa = 6.74 PDD3560 pKa = 3.04 WDD3562 pKa = 3.72 EE3563 pKa = 4.23 LLSKK3567 pKa = 10.17 RR3568 pKa = 11.84 WNASQTPFSRR3578 pKa = 11.84 IDD3580 pKa = 3.43 LKK3582 pKa = 11.3 NAARR3586 pKa = 11.84 CPKK3589 pKa = 9.79 TGMHH3593 pKa = 6.53 MIGRR3597 pKa = 11.84 VPCGSHH3603 pKa = 4.92 THH3605 pKa = 6.59 ISDD3608 pKa = 4.05 ADD3610 pKa = 3.86 LTSLSMSVSYY3620 pKa = 10.11 WSSNKK3625 pKa = 7.69 TTLDD3629 pKa = 4.13 FIEE3632 pKa = 4.73 TCAKK3636 pKa = 9.53 LTGKK3640 pKa = 9.34 PKK3642 pKa = 10.44 KK3643 pKa = 10.45 DD3644 pKa = 2.78 IAARR3648 pKa = 11.84 LQGTNWHH3655 pKa = 6.49 HH3656 pKa = 6.2 LFHH3659 pKa = 6.57 RR3660 pKa = 11.84 RR3661 pKa = 11.84 KK3662 pKa = 7.89 MQVVTTFQHH3671 pKa = 6.25 SYY3673 pKa = 11.43 KK3674 pKa = 10.7 NGCSWEE3680 pKa = 4.03 KK3681 pKa = 9.8 TGCNFKK3687 pKa = 10.78 PGDD3690 pKa = 3.86 LVTICFDD3697 pKa = 3.8 RR3698 pKa = 11.84 GCVVGVVLEE3707 pKa = 4.05 RR3708 pKa = 11.84 ARR3710 pKa = 11.84 DD3711 pKa = 3.59 YY3712 pKa = 11.06 VVQYY3716 pKa = 7.05 EE3717 pKa = 4.59 TRR3719 pKa = 11.84 TSTPLYY3725 pKa = 10.5 AISLSMNVNVKK3736 pKa = 8.59 HH3737 pKa = 4.77 TTLRR3741 pKa = 11.84 RR3742 pKa = 11.84 AVTLKK3747 pKa = 10.65 GVQEE3751 pKa = 3.87 EE3752 pKa = 4.38 AFLNVKK3758 pKa = 8.34 TMHH3761 pKa = 6.11 YY3762 pKa = 8.87 CHH3764 pKa = 7.3 SIGLRR3769 pKa = 11.84 NDD3771 pKa = 2.74 ISEE3774 pKa = 4.04 VAEE3777 pKa = 4.01 RR3778 pKa = 11.84 EE3779 pKa = 4.04 KK3780 pKa = 10.88 KK3781 pKa = 9.64 YY3782 pKa = 11.19 DD3783 pKa = 3.53 SLIVSDD3789 pKa = 4.17 FDD3791 pKa = 4.6 NRR3793 pKa = 11.84 IHH3795 pKa = 6.54 HH3796 pKa = 5.99 QFNEE3800 pKa = 3.78 KK3801 pKa = 10.52 DD3802 pKa = 2.95 ILKK3805 pKa = 9.65 YY3806 pKa = 10.62 QEE3808 pKa = 4.28 ADD3810 pKa = 3.28 AITIVSGKK3818 pKa = 9.67 SRR3820 pKa = 11.84 AVMVTWIMTEE3830 pKa = 3.43 SDD3832 pKa = 3.23 LRR3834 pKa = 11.84 LTMWHH3839 pKa = 6.27 GKK3841 pKa = 9.51 PYY3843 pKa = 10.31 IEE3845 pKa = 5.77 LKK3847 pKa = 10.18 TKK3849 pKa = 9.69 DD3850 pKa = 4.01 TILMSILDD3858 pKa = 3.84 SAGEE3862 pKa = 4.1 RR3863 pKa = 11.84 IALGNDD3869 pKa = 3.16 EE3870 pKa = 4.61 YY3871 pKa = 11.52 RR3872 pKa = 11.84 WIPEE3876 pKa = 3.9 GDD3878 pKa = 3.79 DD3879 pKa = 3.14 TRR3881 pKa = 11.84 MLRR3884 pKa = 11.84 VCDD3887 pKa = 4.4 TIPRR3891 pKa = 11.84 LQKK3894 pKa = 10.78 LLNKK3898 pKa = 9.13 TDD3900 pKa = 3.46 EE3901 pKa = 4.64 GLVEE3905 pKa = 4.73 LKK3907 pKa = 9.71 WLTMNPRR3914 pKa = 11.84 LNPIKK3919 pKa = 10.39 VVKK3922 pKa = 10.34 KK3923 pKa = 9.99 HH3924 pKa = 5.55 MLSEE3928 pKa = 4.31 GLSEE3932 pKa = 4.15 EE3933 pKa = 4.69 GEE3935 pKa = 4.0 MDD3937 pKa = 3.93 VEE3939 pKa = 4.18 EE3940 pKa = 5.24 LNLLLAVPLSEE3951 pKa = 5.41 LVILTSRR3958 pKa = 11.84 SEE3960 pKa = 3.77 IAEE3963 pKa = 3.87 WLSISRR3969 pKa = 11.84 HH3970 pKa = 3.85 MFGYY3974 pKa = 10.35 KK3975 pKa = 9.88 LDD3977 pKa = 4.85 GIYY3980 pKa = 10.46 HH3981 pKa = 6.25 SGAGGMINLAGPIVVYY3997 pKa = 10.2 KK3998 pKa = 10.68 KK3999 pKa = 10.68 KK4000 pKa = 10.48 LLPPSMTGGHH4010 pKa = 6.56 LVLDD4014 pKa = 4.62 IGDD4017 pKa = 3.66 QHH4019 pKa = 5.83 WNKK4022 pKa = 9.41 VRR4024 pKa = 11.84 EE4025 pKa = 4.2 QYY4027 pKa = 10.8 SEE4029 pKa = 3.88 NNLRR4033 pKa = 11.84 GLVKK4037 pKa = 10.5 HH4038 pKa = 5.88 GFKK4041 pKa = 9.6 VTSPEE4046 pKa = 4.06 SAQQRR4051 pKa = 11.84 ATSNMEE4057 pKa = 3.93 RR4058 pKa = 11.84 LKK4060 pKa = 10.66 QSPLYY4065 pKa = 10.12 PMLDD4069 pKa = 3.24 AVRR4072 pKa = 11.84 DD4073 pKa = 3.99 MTQGSYY4079 pKa = 11.06 SKK4081 pKa = 9.98 TPLTFTNVRR4090 pKa = 11.84 AHH4092 pKa = 6.37 EE4093 pKa = 4.15 VDD4095 pKa = 4.21 KK4096 pKa = 11.59 EE4097 pKa = 4.09 MGDD4100 pKa = 4.04 LIIPKK4105 pKa = 9.84 ILVDD4109 pKa = 3.9 TNMGWEE4115 pKa = 4.52 LEE4117 pKa = 4.38 TAHH4120 pKa = 7.79 LEE4122 pKa = 3.96 EE4123 pKa = 4.56 VPIHH4127 pKa = 5.98 VRR4129 pKa = 11.84 QMWDD4133 pKa = 3.12 EE4134 pKa = 4.1 TDD4136 pKa = 3.73 LLDD4139 pKa = 4.25 WNASYY4144 pKa = 11.16 APSNQLRR4151 pKa = 11.84 LKK4153 pKa = 7.92 TTLPTGKK4160 pKa = 9.78 RR4161 pKa = 11.84 RR4162 pKa = 11.84 TEE4164 pKa = 3.32 RR4165 pKa = 11.84 KK4166 pKa = 8.95 MIYY4169 pKa = 8.84 TKK4171 pKa = 11.0 YY4172 pKa = 9.01 PIQSRR4177 pKa = 11.84 VVLTKK4182 pKa = 10.55 AANQEE4187 pKa = 4.21 FNAVTGRR4194 pKa = 11.84 IGNASIIRR4202 pKa = 11.84 KK4203 pKa = 9.4 YY4204 pKa = 10.59 NLNIQYY4210 pKa = 9.35 EE4211 pKa = 4.64 LKK4213 pKa = 10.82 NMCRR4217 pKa = 11.84 EE4218 pKa = 4.03 LFVANWQSICAGYY4231 pKa = 9.91 QADD4234 pKa = 3.85 QVSPSPEE4241 pKa = 4.41 NILEE4245 pKa = 4.15 WLSEE4249 pKa = 4.08 KK4250 pKa = 10.42 PDD4252 pKa = 3.39 GVNIGEE4258 pKa = 4.26 EE4259 pKa = 4.0 LQSYY4263 pKa = 10.11 IEE4265 pKa = 5.51 DD4266 pKa = 3.84 GFQTHH4271 pKa = 7.73 PISDD4275 pKa = 3.99 VNVHH4279 pKa = 6.53 LKK4281 pKa = 10.94 LEE4283 pKa = 4.52 ALLKK4287 pKa = 10.0 DD4288 pKa = 3.58 QPVEE4292 pKa = 4.18 SNQALKK4298 pKa = 10.94 ARR4300 pKa = 11.84 IIVWQAKK4307 pKa = 8.18 GICAMYY4313 pKa = 10.2 SGTFIQIKK4321 pKa = 10.17 KK4322 pKa = 9.71 RR4323 pKa = 11.84 LKK4325 pKa = 9.32 KK4326 pKa = 10.29 LLRR4329 pKa = 11.84 AEE4331 pKa = 4.0 IVYY4334 pKa = 10.06 TDD4336 pKa = 3.57 GLEE4339 pKa = 3.98 PTEE4342 pKa = 3.98 IADD4345 pKa = 3.57 VVRR4348 pKa = 11.84 GIKK4351 pKa = 10.3 DD4352 pKa = 3.42 FSVLIEE4358 pKa = 5.32 DD4359 pKa = 4.52 DD4360 pKa = 3.76 LTRR4363 pKa = 11.84 QDD4365 pKa = 3.72 SQTDD4369 pKa = 3.09 SDD4371 pKa = 4.4 TINVEE4376 pKa = 3.81 FGVYY4380 pKa = 10.31 DD4381 pKa = 4.01 LLGLDD4386 pKa = 3.56 RR4387 pKa = 11.84 RR4388 pKa = 11.84 VAASWRR4394 pKa = 11.84 RR4395 pKa = 11.84 VHH4397 pKa = 6.18 EE4398 pKa = 4.08 LWRR4401 pKa = 11.84 FKK4403 pKa = 11.16 GKK4405 pKa = 9.73 DD4406 pKa = 3.35 VRR4408 pKa = 11.84 GVWQEE4413 pKa = 3.64 MRR4415 pKa = 11.84 LTGQATTALGNAVVNLAVHH4434 pKa = 6.2 WRR4436 pKa = 11.84 LVSQLGPAMKK4446 pKa = 9.61 MYY4448 pKa = 10.92 LLLGDD4453 pKa = 4.6 DD4454 pKa = 4.09 SLFFSRR4460 pKa = 11.84 TTIDD4464 pKa = 3.05 ATSLRR4469 pKa = 11.84 RR4470 pKa = 11.84 NIADD4474 pKa = 3.73 YY4475 pKa = 11.86 YY4476 pKa = 10.23 NMKK4479 pKa = 10.5 SKK4481 pKa = 11.04 AFVYY4485 pKa = 10.02 KK4486 pKa = 10.76 DD4487 pKa = 3.07 HH4488 pKa = 6.75 GTFCSMMAYY4497 pKa = 9.85 KK4498 pKa = 10.42 NPQGGAGIGPDD4509 pKa = 3.77 FVRR4512 pKa = 11.84 LKK4514 pKa = 10.77 RR4515 pKa = 11.84 RR4516 pKa = 11.84 FEE4518 pKa = 4.19 VPSGVSEE4525 pKa = 4.37 TNLTNTVARR4534 pKa = 11.84 KK4535 pKa = 8.73 MSYY4538 pKa = 11.06 CLMLGNLPIVKK4549 pKa = 10.15 KK4550 pKa = 10.55 LVEE4553 pKa = 4.32 DD4554 pKa = 3.65 MGWPIEE4560 pKa = 3.97 LQQWYY4565 pKa = 9.67 DD4566 pKa = 3.72 PSPLIDD4572 pKa = 4.66 SICDD4576 pKa = 3.4 KK4577 pKa = 11.36 YY4578 pKa = 11.74 NMSSAEE4584 pKa = 4.1 VEE4586 pKa = 4.24 SHH4588 pKa = 4.62 ITALVDD4594 pKa = 3.87 MIRR4597 pKa = 11.84 SRR4599 pKa = 11.84 TMYY4602 pKa = 10.41 EE4603 pKa = 3.13 IDD4605 pKa = 4.07 FDD4607 pKa = 5.0 VISQRR4612 pKa = 3.71
Molecular weight: 519.63 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.603
IPC2_protein 5.563
IPC_protein 5.614
Toseland 5.944
ProMoST 5.931
Dawson 5.842
Bjellqvist 5.868
Wikipedia 5.83
Rodwell 5.817
Grimsley 6.071
Solomon 5.842
Lehninger 5.83
Nozaki 6.084
DTASelect 6.275
Thurlkill 6.249
EMBOSS 6.211
Sillero 6.186
Patrickios 4.075
IPC_peptide 5.855
IPC2_peptide 6.186
IPC2.peptide.svr19 6.125
Protein with the highest isoelectric point:
>tr|Q53I73|Q53I73_PHEV1 Uncharacterized protein polyprotein OS=Phytophthora endornavirus 1 OX=310750 GN=polyprotein PE=2 SV=1
MM1 pKa = 7.61 SSTISNYY8 pKa = 9.88 QKK10 pKa = 10.3 LQSRR14 pKa = 11.84 KK15 pKa = 6.35 TLRR18 pKa = 11.84 GGRR21 pKa = 11.84 RR22 pKa = 11.84 TGVGGLPVALNQEE35 pKa = 4.4 QILTLRR41 pKa = 11.84 KK42 pKa = 9.62 KK43 pKa = 11.0 LNLKK47 pKa = 6.13 VTKK50 pKa = 10.14 RR51 pKa = 11.84 FNYY54 pKa = 9.91 LKK56 pKa = 10.87 SIDD59 pKa = 3.78 KK60 pKa = 10.33 KK61 pKa = 9.15 YY62 pKa = 11.18 KK63 pKa = 10.69 EE64 pKa = 4.01 MVKK67 pKa = 9.43 TSKK70 pKa = 10.95 YY71 pKa = 9.26 PGRR74 pKa = 11.84 LVPISKK80 pKa = 10.35 ALNKK84 pKa = 10.21 KK85 pKa = 9.8 AMQRR89 pKa = 11.84 MTRR92 pKa = 11.84 NIIIPDD98 pKa = 3.81 CMHH101 pKa = 7.44 PSQLLAVKK109 pKa = 9.91 VAIANNTDD117 pKa = 2.15 KK118 pKa = 11.13 WFITRR123 pKa = 11.84 DD124 pKa = 3.14 AFLEE128 pKa = 4.1 LKK130 pKa = 10.49 NLSEE134 pKa = 4.57 LANGSQQEE142 pKa = 4.02 VRR144 pKa = 11.84 LSVLRR149 pKa = 11.84 SKK151 pKa = 10.73 LYY153 pKa = 10.41 KK154 pKa = 8.31 YY155 pKa = 9.2 TSIGKK160 pKa = 8.84 EE161 pKa = 4.1 VIPGEE166 pKa = 4.03 ANYY169 pKa = 9.85 FRR171 pKa = 11.84 TWFKK175 pKa = 10.37 WLSSNYY181 pKa = 8.53 NNSMYY186 pKa = 10.37 WMWAKK191 pKa = 10.43 YY192 pKa = 7.32 QTAATILCDD201 pKa = 4.78 RR202 pKa = 11.84 IVEE205 pKa = 4.35 TAAGCVMYY213 pKa = 9.98 IDD215 pKa = 5.35 CEE217 pKa = 3.99 PAPAEE222 pKa = 4.21 TVVEE226 pKa = 4.08 CAYY229 pKa = 10.99 CGMLNHH235 pKa = 5.83 MTSADD240 pKa = 3.31 NVMCGSCYY248 pKa = 10.69 GDD250 pKa = 3.48 LEE252 pKa = 4.44 VTIEE256 pKa = 4.08 SAIPGEE262 pKa = 4.14 PIIEE266 pKa = 4.21 LVLNMLQGHH275 pKa = 6.88 FGMAMLEE282 pKa = 3.95 QLSLSNYY289 pKa = 9.82 LDD291 pKa = 3.85 LSALAEE297 pKa = 4.28 SGIGPSIINHH307 pKa = 6.85 DD308 pKa = 4.13 LMIVKK313 pKa = 10.22 QILSRR318 pKa = 11.84 SMNMAVKK325 pKa = 10.41 VPSNLSLKK333 pKa = 10.08 EE334 pKa = 3.95 LSTLRR339 pKa = 11.84 FTLGTDD345 pKa = 3.68 MCCPIHH351 pKa = 6.93 PNTSGARR358 pKa = 11.84 KK359 pKa = 9.82 SSAEE363 pKa = 3.98 VSWVVTQLRR372 pKa = 11.84 QLTSSKK378 pKa = 10.92 GKK380 pKa = 10.31 IIVVDD385 pKa = 3.55 SMNVLQCLEE394 pKa = 4.19 LQDD397 pKa = 4.53 GVIEE401 pKa = 4.3 VVNDD405 pKa = 3.06 IAEE408 pKa = 4.18 ADD410 pKa = 3.82 IAWGQVEE417 pKa = 4.52 HH418 pKa = 6.39 VVIYY422 pKa = 10.27 LPNALEE428 pKa = 4.0 LSCIFSAAPINVCVTTLQLDD448 pKa = 3.85 PKK450 pKa = 9.74 DD451 pKa = 3.99 PEE453 pKa = 4.73 MLTEE457 pKa = 4.53 WDD459 pKa = 3.65 TQQIGEE465 pKa = 4.62 TVWWSPVYY473 pKa = 11.0 SNLAASQDD481 pKa = 3.83 VGDD484 pKa = 3.95 VTLLLGDD491 pKa = 4.41 HH492 pKa = 5.66 YY493 pKa = 10.13 TVNNHH498 pKa = 4.72 NTILNASKK506 pKa = 10.27 INKK509 pKa = 8.63 IGYY512 pKa = 6.9 FTRR515 pKa = 11.84 CEE517 pKa = 3.61 IHH519 pKa = 6.89 RR520 pKa = 11.84 SEE522 pKa = 4.3 GLPVEE527 pKa = 4.72 LLTDD531 pKa = 4.04 VIGSLIEE538 pKa = 3.8 EE539 pKa = 4.04 EE540 pKa = 4.8 RR541 pKa = 11.84 EE542 pKa = 4.05 FKK544 pKa = 10.8 IPTVDD549 pKa = 2.88 MDD551 pKa = 4.23 ALVTRR556 pKa = 11.84 FGGAVIKK563 pKa = 9.86 TKK565 pKa = 10.27 TIALDD570 pKa = 3.77 RR571 pKa = 11.84 VFLRR575 pKa = 11.84 YY576 pKa = 9.68 LLNKK580 pKa = 9.06 TMLGNMGYY588 pKa = 9.03 NQTVEE593 pKa = 4.23 YY594 pKa = 10.09 AISLCYY600 pKa = 9.99 SRR602 pKa = 11.84 YY603 pKa = 9.96 VMDD606 pKa = 3.73 GRR608 pKa = 11.84 EE609 pKa = 4.11 MNFSRR614 pKa = 11.84 ISAEE618 pKa = 3.75 SCRR621 pKa = 11.84 DD622 pKa = 3.33 HH623 pKa = 8.37 AYY625 pKa = 9.75 VAVMXTGLTSTEE637 pKa = 4.18 FKK639 pKa = 10.5 TGEE642 pKa = 4.3 TVLGPNNGAQQVINVLSLGAMQGLWAVGLDD672 pKa = 3.62 LCEE675 pKa = 4.01 QLLPEE680 pKa = 5.61 PISEE684 pKa = 4.18 AVKK687 pKa = 9.2 KK688 pKa = 9.14 TITWLKK694 pKa = 9.86 QGNTSDD700 pKa = 3.89 YY701 pKa = 8.81 QTTDD705 pKa = 1.75 IWEE708 pKa = 4.22 KK709 pKa = 10.76 LRR711 pKa = 11.84 DD712 pKa = 3.5 WVYY715 pKa = 11.38 GNTFDD720 pKa = 3.45 SCKK723 pKa = 10.7 YY724 pKa = 9.71 YY725 pKa = 11.17 VEE727 pKa = 4.63 TKK729 pKa = 9.09 WKK731 pKa = 8.75 YY732 pKa = 9.53 QEE734 pKa = 4.57 PEE736 pKa = 4.41 SNCDD740 pKa = 3.13 HH741 pKa = 7.14 HH742 pKa = 9.33 SPDD745 pKa = 4.82 CDD747 pKa = 3.77 DD748 pKa = 4.0 EE749 pKa = 4.58 QVGVDD754 pKa = 3.74 DD755 pKa = 5.93 QDD757 pKa = 3.7 TLRR760 pKa = 11.84 CLCCLLFKK768 pKa = 10.84 ASPVTKK774 pKa = 10.32 LCKK777 pKa = 10.29 CCTLSSKK784 pKa = 10.75 CNHH787 pKa = 6.48 KK788 pKa = 10.52 CSHH791 pKa = 6.17 TCTSEE796 pKa = 4.38 LDD798 pKa = 3.81 HH799 pKa = 6.98 ICNKK803 pKa = 9.6 KK804 pKa = 10.3 CKK806 pKa = 8.63 HH807 pKa = 5.34 QKK809 pKa = 9.49 ILCDD813 pKa = 3.47 CCGVPTCFDD822 pKa = 3.85 EE823 pKa = 6.36 CPVCQTPVTWVLPISLAAKK842 pKa = 9.23 EE843 pKa = 4.04 ISNASRR849 pKa = 11.84 RR850 pKa = 11.84 NRR852 pKa = 11.84 PVHH855 pKa = 4.55 MAKK858 pKa = 9.8 PRR860 pKa = 11.84 KK861 pKa = 8.87 IDD863 pKa = 3.32 RR864 pKa = 11.84 EE865 pKa = 4.07 KK866 pKa = 10.79 IEE868 pKa = 4.32 DD869 pKa = 3.43 QEE871 pKa = 4.42 FTVKK875 pKa = 10.66 GEE877 pKa = 3.98 PVSRR881 pKa = 11.84 VPVFKK886 pKa = 9.92 THH888 pKa = 6.3 GLTLGLTGCNIQEE901 pKa = 4.12 VMEE904 pKa = 4.27 NQAEE908 pKa = 4.2 IQAKK912 pKa = 9.67 VNEE915 pKa = 4.49 LKK917 pKa = 11.17 LEE919 pKa = 4.21 DD920 pKa = 3.93 VEE922 pKa = 6.0 VYY924 pKa = 10.81 DD925 pKa = 4.84 PDD927 pKa = 3.81 TLEE930 pKa = 4.68 SIGLFLLIDD939 pKa = 3.5 HH940 pKa = 6.65 TLISEE945 pKa = 4.01 PAKK948 pKa = 10.43 PGEE951 pKa = 4.15 HH952 pKa = 6.51 TISEE956 pKa = 4.36 LVEE959 pKa = 3.71 EE960 pKa = 4.61 AEE962 pKa = 4.1 QRR964 pKa = 11.84 NASTSVDD971 pKa = 3.45 TTPRR975 pKa = 11.84 EE976 pKa = 4.31 HH977 pKa = 6.45 QDD979 pKa = 2.93 KK980 pKa = 10.22 PVALDD985 pKa = 3.58 VPADD989 pKa = 3.86 KK990 pKa = 10.59 QSHH993 pKa = 6.75 DD994 pKa = 4.3 RR995 pKa = 11.84 LSMLAPVVRR1004 pKa = 11.84 RR1005 pKa = 11.84 ACLNGLMKK1013 pKa = 10.61 NWGEE1017 pKa = 3.83 VQPYY1021 pKa = 10.03 FKK1023 pKa = 8.81 TTDD1026 pKa = 3.29 ADD1028 pKa = 3.94 EE1029 pKa = 5.44 AGTTQLVLLAEE1040 pKa = 4.74 GFSSYY1045 pKa = 7.41 VTNDD1049 pKa = 2.69 WLAVVATHH1057 pKa = 7.25 SISAEE1062 pKa = 3.89 DD1063 pKa = 3.8 NLCGFHH1069 pKa = 7.12 ALNLGFEE1076 pKa = 4.59 GASLRR1081 pKa = 11.84 RR1082 pKa = 11.84 LRR1084 pKa = 11.84 EE1085 pKa = 3.69 VSKK1088 pKa = 11.0 KK1089 pKa = 10.63 DD1090 pKa = 3.13 DD1091 pKa = 3.46 WFEE1094 pKa = 3.89 LTDD1097 pKa = 3.56 LVNYY1101 pKa = 8.86 MRR1103 pKa = 11.84 EE1104 pKa = 3.82 EE1105 pKa = 4.06 DD1106 pKa = 3.89 RR1107 pKa = 11.84 NLLVMKK1113 pKa = 10.54 DD1114 pKa = 3.77 EE1115 pKa = 4.35 MVDD1118 pKa = 3.4 VYY1120 pKa = 11.29 TFDD1123 pKa = 4.64 PYY1125 pKa = 11.09 NSVYY1129 pKa = 10.76 VSVEE1133 pKa = 3.95 HH1134 pKa = 6.43 TGSTSSGHH1142 pKa = 5.98 WSPISMVQIKK1152 pKa = 8.61 PAPSLPNWTGVTDD1165 pKa = 4.56 RR1166 pKa = 11.84 NTMSQILLSWGLSVDD1181 pKa = 3.77 TEE1183 pKa = 4.18 FDD1185 pKa = 3.82 DD1186 pKa = 5.91 LSVSQRR1192 pKa = 11.84 ITYY1195 pKa = 10.14 SWMQYY1200 pKa = 8.86 NEE1202 pKa = 3.84 EE1203 pKa = 4.13 VGRR1206 pKa = 11.84 SKK1208 pKa = 11.17 AIVSQTLSLSSEE1220 pKa = 3.93 NGVGYY1225 pKa = 9.91 LHH1227 pKa = 7.37 SGTNTKK1233 pKa = 10.57 NDD1235 pKa = 3.05 IRR1237 pKa = 11.84 SGEE1240 pKa = 4.15 VFLEE1244 pKa = 4.28 IPQQYY1249 pKa = 8.49 VPSMSMLNSSWSLVQNSFEE1268 pKa = 4.28 YY1269 pKa = 9.98 NQPHH1273 pKa = 6.74 SYY1275 pKa = 11.18 SDD1277 pKa = 4.2 TIPLNCSQRR1286 pKa = 11.84 LVQEE1290 pKa = 3.69 VRR1292 pKa = 11.84 EE1293 pKa = 4.07 QIKK1296 pKa = 8.49 TLVQLGFTLDD1306 pKa = 3.33 NYY1308 pKa = 10.83 LPEE1311 pKa = 4.96 IPPGYY1316 pKa = 10.48 YY1317 pKa = 9.99 NLHH1320 pKa = 5.4 QKK1322 pKa = 10.03 GRR1324 pKa = 11.84 AQTISEE1330 pKa = 4.22 GVVRR1334 pKa = 11.84 CRR1336 pKa = 11.84 LTKK1339 pKa = 10.6 EE1340 pKa = 3.95 NIKK1343 pKa = 9.77 TGDD1346 pKa = 3.71 SILVVVSGKK1355 pKa = 10.23 GYY1357 pKa = 7.94 SVRR1360 pKa = 11.84 RR1361 pKa = 11.84 ITRR1364 pKa = 11.84 EE1365 pKa = 3.85 GAWMIFPFVTTQRR1378 pKa = 11.84 RR1379 pKa = 11.84 TTIKK1383 pKa = 10.06 FLNPRR1388 pKa = 11.84 SSCTSTLLRR1397 pKa = 11.84 LQALLQTNPDD1407 pKa = 3.37 TSRR1410 pKa = 11.84 TLQLLQASEE1419 pKa = 4.42 CTLAVPGWGKK1429 pKa = 7.46 STKK1432 pKa = 9.48 IVKK1435 pKa = 9.97 EE1436 pKa = 3.82 FDD1438 pKa = 2.97 TDD1440 pKa = 3.77 TTVTCVTSEE1449 pKa = 3.9 AVKK1452 pKa = 10.88 NLVAMGLPRR1461 pKa = 11.84 NKK1463 pKa = 8.59 VTSVEE1468 pKa = 4.02 RR1469 pKa = 11.84 AVEE1472 pKa = 4.34 SKK1474 pKa = 10.07 IHH1476 pKa = 5.1 TKK1478 pKa = 10.41 KK1479 pKa = 10.69 LAIDD1483 pKa = 3.6 EE1484 pKa = 4.38 CTQVDD1489 pKa = 3.82 WLMVHH1494 pKa = 6.09 MMCGDD1499 pKa = 3.41 EE1500 pKa = 4.64 VEE1502 pKa = 4.97 IITLAGDD1509 pKa = 4.01 SFQIGAVDD1517 pKa = 4.98 FSASTGEE1524 pKa = 4.14 RR1525 pKa = 11.84 TITSCNMFSLHH1536 pKa = 6.13 QNTYY1540 pKa = 9.59 NNSHH1544 pKa = 6.97 RR1545 pKa = 11.84 FGQPLCSQLTVLNPRR1560 pKa = 11.84 LTTDD1564 pKa = 3.54 ALHH1567 pKa = 4.73 QTSYY1571 pKa = 11.13 SVHH1574 pKa = 5.99 NLSSLDD1580 pKa = 3.87 LNVLGSVIAQEE1591 pKa = 4.17 RR1592 pKa = 11.84 PGVILTFHH1600 pKa = 6.95 QITKK1604 pKa = 10.04 SQIQRR1609 pKa = 11.84 AFGRR1613 pKa = 11.84 TIKK1616 pKa = 10.04 TSLTTGDD1623 pKa = 3.44 VKK1625 pKa = 10.1 TVHH1628 pKa = 6.68 SYY1630 pKa = 9.86 QGKK1633 pKa = 7.87 EE1634 pKa = 3.77 SSRR1637 pKa = 11.84 VMVIQDD1643 pKa = 3.8 FLSPAGVHH1651 pKa = 4.9 TDD1653 pKa = 2.72 RR1654 pKa = 11.84 RR1655 pKa = 11.84 YY1656 pKa = 11.24 LMSAASRR1663 pKa = 11.84 ASNHH1667 pKa = 6.41 LIWVTIQSPINSLVLSDD1684 pKa = 4.09 HH1685 pKa = 6.78 LKK1687 pKa = 9.97 TNILVGGHH1695 pKa = 6.82 LSDD1698 pKa = 5.52 IIDD1701 pKa = 3.52 NTVITLCNRR1710 pKa = 11.84 FKK1712 pKa = 11.26 FEE1714 pKa = 4.03 MSLEE1718 pKa = 4.07 TMRR1721 pKa = 11.84 NVVEE1725 pKa = 4.14 YY1726 pKa = 10.98 LFGEE1730 pKa = 4.59 YY1731 pKa = 10.33 EE1732 pKa = 4.24 STHH1735 pKa = 7.13 SDD1737 pKa = 3.62 EE1738 pKa = 4.42 ITLKK1742 pKa = 9.52 TIHH1745 pKa = 6.15 ITGPTEE1751 pKa = 3.55 NEE1753 pKa = 3.92 YY1754 pKa = 10.53 QRR1756 pKa = 11.84 GYY1758 pKa = 10.76 IKK1760 pKa = 10.67 FSQPEE1765 pKa = 4.05 EE1766 pKa = 3.77 EE1767 pKa = 4.11 FLRR1770 pKa = 11.84 RR1771 pKa = 11.84 GRR1773 pKa = 11.84 TYY1775 pKa = 11.26 LVTKK1779 pKa = 9.73 PNLGSPSEE1787 pKa = 4.17 EE1788 pKa = 4.07 PEE1790 pKa = 4.02 VVYY1793 pKa = 10.42 IAEE1796 pKa = 4.09 DD1797 pKa = 3.36 WKK1799 pKa = 10.93 PEE1801 pKa = 3.8 GKK1803 pKa = 9.16 IDD1805 pKa = 4.65 EE1806 pKa = 4.57 RR1807 pKa = 11.84 YY1808 pKa = 9.89 EE1809 pKa = 4.1 LNDD1812 pKa = 3.44 YY1813 pKa = 10.69 AVSNQKK1819 pKa = 7.82 TQVVFGTKK1827 pKa = 9.65 RR1828 pKa = 11.84 ALSTLILPMSINTAGWKK1845 pKa = 8.03 ITLSKK1850 pKa = 10.96 QEE1852 pKa = 4.12 ANVLVTIEE1860 pKa = 4.75 KK1861 pKa = 10.33 YY1862 pKa = 10.87 GKK1864 pKa = 7.55 TLNFIWDD1871 pKa = 3.77 NQLGGVDD1878 pKa = 4.03 LTNHH1882 pKa = 6.96 KK1883 pKa = 10.1 ALQVGLRR1890 pKa = 11.84 LLINTGLLEE1899 pKa = 4.18 RR1900 pKa = 11.84 VLPEE1904 pKa = 3.8 EE1905 pKa = 4.03 LHH1907 pKa = 5.93 NLNLFEE1913 pKa = 4.48 LTLNEE1918 pKa = 4.21 DD1919 pKa = 3.32 RR1920 pKa = 11.84 VMSNAEE1926 pKa = 3.91 LEE1928 pKa = 4.76 EE1929 pKa = 4.09 IAEE1932 pKa = 4.36 MGSVIHH1938 pKa = 6.55 MDD1940 pKa = 3.0 EE1941 pKa = 4.9 LMDD1944 pKa = 4.25 SEE1946 pKa = 6.25 AIMEE1950 pKa = 4.32 PSVRR1954 pKa = 11.84 QGWTHH1959 pKa = 7.72 LINITNGRR1967 pKa = 11.84 LSSEE1971 pKa = 3.98 IQQEE1975 pKa = 4.41 LIVEE1979 pKa = 4.5 SKK1981 pKa = 10.47 NAPNEE1986 pKa = 3.75 SFYY1989 pKa = 9.25 THH1991 pKa = 6.12 KK1992 pKa = 9.86 TGMTLVNYY2000 pKa = 10.35 SRR2002 pKa = 11.84 LSKK2005 pKa = 10.69 LADD2008 pKa = 3.28 AARR2011 pKa = 11.84 RR2012 pKa = 11.84 TSLEE2016 pKa = 4.01 EE2017 pKa = 3.8 LPLPLRR2023 pKa = 11.84 TPFGWVDD2030 pKa = 3.31 VKK2032 pKa = 10.95 RR2033 pKa = 11.84 HH2034 pKa = 5.72 NGCNPCAGISLRR2046 pKa = 11.84 HH2047 pKa = 6.16 HH2048 pKa = 6.87 DD2049 pKa = 4.32 SWWLIDD2055 pKa = 3.27 NDD2057 pKa = 4.08 YY2058 pKa = 10.31 YY2059 pKa = 11.27 RR2060 pKa = 11.84 KK2061 pKa = 10.08 GSRR2064 pKa = 11.84 RR2065 pKa = 11.84 VQFNEE2070 pKa = 3.18 EE2071 pKa = 4.06 STRR2074 pKa = 11.84 DD2075 pKa = 3.27 EE2076 pKa = 4.57 AIIYY2080 pKa = 7.66 VLKK2083 pKa = 10.67 GLQLEE2088 pKa = 4.55 HH2089 pKa = 6.37 TLEE2092 pKa = 4.53 DD2093 pKa = 3.46 VVDD2096 pKa = 4.27 PQEE2099 pKa = 4.17 SSHH2102 pKa = 7.14 PFFCVDD2108 pKa = 3.52 GPGHH2112 pKa = 6.04 EE2113 pKa = 4.56 VWCSNHH2119 pKa = 6.13 EE2120 pKa = 4.2 SLDD2123 pKa = 3.77 FCDD2126 pKa = 3.62 TLMDD2130 pKa = 5.68 RR2131 pKa = 11.84 ISCFKK2136 pKa = 10.3 TYY2138 pKa = 10.21 TEE2140 pKa = 4.75 SKK2142 pKa = 10.68 FEE2144 pKa = 4.15 YY2145 pKa = 10.52 KK2146 pKa = 10.68 DD2147 pKa = 3.4 FTEE2150 pKa = 5.8 NNLTWLQDD2158 pKa = 3.42 VADD2161 pKa = 3.87 KK2162 pKa = 11.12 MEE2164 pKa = 4.0 VFGMYY2169 pKa = 10.37 NITKK2173 pKa = 10.15 PGGDD2177 pKa = 4.28 KK2178 pKa = 10.41 NSKK2181 pKa = 8.85 WNEE2184 pKa = 3.71 SLLQVLNADD2193 pKa = 3.94 GSRR2196 pKa = 11.84 FFVLYY2201 pKa = 8.71 WDD2203 pKa = 3.66 SVFYY2207 pKa = 11.14 YY2208 pKa = 10.47 VDD2210 pKa = 3.75 CDD2212 pKa = 3.66 NDD2214 pKa = 3.56 DD2215 pKa = 4.67 GYY2217 pKa = 10.79 IQQFHH2222 pKa = 6.11 SWVKK2226 pKa = 9.67 VDD2228 pKa = 4.33 LVEE2231 pKa = 4.21 MANKK2235 pKa = 9.83 LFEE2238 pKa = 4.67 VGLEE2242 pKa = 3.94 ARR2244 pKa = 11.84 RR2245 pKa = 11.84 SRR2247 pKa = 11.84 LSTLLLSARR2256 pKa = 11.84 DD2257 pKa = 3.75 TVFGAGVNEE2266 pKa = 5.08 DD2267 pKa = 4.21 GLILDD2272 pKa = 4.98 LDD2274 pKa = 3.43 QHH2276 pKa = 6.53 KK2277 pKa = 10.35 FNKK2280 pKa = 8.01 TAVYY2284 pKa = 9.04 NHH2286 pKa = 6.77 LVQRR2290 pKa = 11.84 MGEE2293 pKa = 4.13 MKK2295 pKa = 10.48 LKK2297 pKa = 10.52 QSALSRR2303 pKa = 11.84 RR2304 pKa = 11.84 PFFHH2308 pKa = 6.71 GKK2310 pKa = 9.03 IAIEE2314 pKa = 3.93 TLKK2317 pKa = 10.96 NQVKK2321 pKa = 6.85 TTLRR2325 pKa = 11.84 GGVVEE2330 pKa = 4.71 EE2331 pKa = 4.98 CPICTGSSVGSEE2343 pKa = 4.09 LVTLIIAHH2351 pKa = 5.89 STDD2354 pKa = 3.31 EE2355 pKa = 4.46 PTTLMLNNPQLLLSNSLWHH2374 pKa = 6.21 HH2375 pKa = 5.96 KK2376 pKa = 9.97 VRR2378 pKa = 11.84 SSEE2381 pKa = 3.79 EE2382 pKa = 3.93 SLFNTTFPSVRR2393 pKa = 11.84 ATFSRR2398 pKa = 11.84 HH2399 pKa = 4.04 ANKK2402 pKa = 9.9 VLGKK2406 pKa = 8.5 ITHH2409 pKa = 5.43 SMKK2412 pKa = 10.28 KK2413 pKa = 9.47 YY2414 pKa = 11.22 AMGEE2418 pKa = 4.07 DD2419 pKa = 3.73 LKK2421 pKa = 11.48 SAGRR2425 pKa = 11.84 LLAASNVLKK2434 pKa = 10.54 KK2435 pKa = 10.74 ASNSEE2440 pKa = 3.77 RR2441 pKa = 11.84 GFEE2444 pKa = 4.34 VFEE2447 pKa = 5.06 HH2448 pKa = 6.23 PTNTCDD2454 pKa = 3.62 NLIVGPLLLAEE2465 pKa = 4.82 PDD2467 pKa = 3.59 SLAEE2471 pKa = 3.42 IWGNEE2476 pKa = 4.07 RR2477 pKa = 11.84 IQVTIIVPAVINSHH2491 pKa = 5.07 SPWYY2495 pKa = 9.96 KK2496 pKa = 10.19 VNSTGGNIQIMEE2508 pKa = 4.74 CGSGLTVKK2516 pKa = 9.99 IRR2518 pKa = 11.84 SEE2520 pKa = 4.0 IYY2522 pKa = 10.38 NSVLNKK2528 pKa = 10.18 PNLTLFGHH2536 pKa = 5.63 TRR2538 pKa = 11.84 CTEE2541 pKa = 4.02 VVGTLFDD2548 pKa = 3.86 YY2549 pKa = 11.22 LIVNTRR2555 pKa = 11.84 GASEE2559 pKa = 4.2 ARR2561 pKa = 11.84 PQKK2564 pKa = 10.03 VWLRR2568 pKa = 11.84 HH2569 pKa = 5.42 PLHH2572 pKa = 6.55 EE2573 pKa = 4.65 VIKK2576 pKa = 10.87 VPILSVNLGEE2586 pKa = 5.78 DD2587 pKa = 3.19 IANKK2591 pKa = 10.43 SIVKK2595 pKa = 9.09 WKK2597 pKa = 10.1 EE2598 pKa = 3.62 FRR2600 pKa = 11.84 CDD2602 pKa = 3.34 PVVLRR2607 pKa = 11.84 RR2608 pKa = 11.84 LEE2610 pKa = 3.98 LRR2612 pKa = 11.84 VNRR2615 pKa = 11.84 PGTNFKK2621 pKa = 10.38 DD2622 pKa = 3.14 LCEE2625 pKa = 4.01 YY2626 pKa = 11.14 ARR2628 pKa = 11.84 TLLHH2632 pKa = 5.86 TRR2634 pKa = 11.84 DD2635 pKa = 3.69 YY2636 pKa = 10.83 TRR2638 pKa = 11.84 LGSWDD2643 pKa = 3.77 TVKK2646 pKa = 10.95 LDD2648 pKa = 3.99 DD2649 pKa = 6.04 LDD2651 pKa = 4.15 MLSHH2655 pKa = 6.51 CQYY2658 pKa = 11.49 AYY2660 pKa = 10.89 YY2661 pKa = 10.37 HH2662 pKa = 6.43 NKK2664 pKa = 10.06 LGNKK2668 pKa = 9.59 SISQMIEE2675 pKa = 3.6 LLNVFDD2681 pKa = 5.07 QSGKK2685 pKa = 10.38 NIPFYY2690 pKa = 11.26 SWLKK2694 pKa = 9.79 GLGVSKK2700 pKa = 10.65 LLDD2703 pKa = 3.54 VTYY2706 pKa = 9.62 STYY2709 pKa = 11.13 AGVMRR2714 pKa = 11.84 DD2715 pKa = 3.18 TGLDD2719 pKa = 3.28 LGLSQTLMEE2728 pKa = 4.38 FCGFIDD2734 pKa = 3.92 EE2735 pKa = 4.69 LVKK2738 pKa = 10.94 NDD2740 pKa = 3.52 TVKK2743 pKa = 11.14 NSVVEE2748 pKa = 3.77 LWNNYY2753 pKa = 7.94 EE2754 pKa = 3.46 PTMYY2758 pKa = 9.88 KK2759 pKa = 9.84 RR2760 pKa = 11.84 HH2761 pKa = 5.5 VSFITWRR2768 pKa = 11.84 AQPTATGEE2776 pKa = 4.24 VGRR2779 pKa = 11.84 LAYY2782 pKa = 10.28 RR2783 pKa = 11.84 LLKK2786 pKa = 10.0 EE2787 pKa = 5.11 FIWEE2791 pKa = 3.91 PHH2793 pKa = 5.73 FEE2795 pKa = 4.65 GDD2797 pKa = 4.54 DD2798 pKa = 3.65 VLRR2801 pKa = 11.84 DD2802 pKa = 4.14 LIPRR2806 pKa = 11.84 GAKK2809 pKa = 10.05 DD2810 pKa = 3.47 DD2811 pKa = 4.11 GKK2813 pKa = 10.98 SEE2815 pKa = 4.03 NSHH2818 pKa = 5.26 TEE2820 pKa = 3.34 EE2821 pKa = 5.53 DD2822 pKa = 4.34 FEE2824 pKa = 5.24 QEE2826 pKa = 3.94 HH2827 pKa = 7.0 SDD2829 pKa = 3.56 FKK2831 pKa = 11.16 HH2832 pKa = 6.94 AVFTSQGTRR2841 pKa = 11.84 GDD2843 pKa = 3.59 VEE2845 pKa = 4.18 PVVKK2849 pKa = 10.28 FINKK2853 pKa = 8.99 IKK2855 pKa = 10.42 HH2856 pKa = 5.92 GYY2858 pKa = 10.17 DD2859 pKa = 3.66 LVTLVCNQGNGEE2871 pKa = 4.21 GVQFPDD2877 pKa = 5.02 DD2878 pKa = 3.48 IRR2880 pKa = 11.84 VVYY2883 pKa = 10.55 IDD2885 pKa = 3.68 MDD2887 pKa = 4.04 GSKK2890 pKa = 10.45 LATLASVGTGEE2901 pKa = 4.36 GLAEE2905 pKa = 4.17 VLSKK2909 pKa = 11.02 LCEE2912 pKa = 4.24 FEE2914 pKa = 5.03 GSMRR2918 pKa = 11.84 DD2919 pKa = 3.5 TLEE2922 pKa = 4.42 KK2923 pKa = 10.58 LLSGPPVTTVYY2934 pKa = 9.52 ATSNCHH2940 pKa = 6.51 LGYY2943 pKa = 8.68 XLADD2947 pKa = 3.95 LVQCKK2952 pKa = 9.63 LVEE2955 pKa = 4.17 LQLFPWPFNPTTKK2968 pKa = 10.4 LEE2970 pKa = 4.11 KK2971 pKa = 10.22 FVAGVTEE2978 pKa = 4.37 RR2979 pKa = 11.84 VLTTTVDD2986 pKa = 3.2 TSGLNRR2992 pKa = 11.84 VKK2994 pKa = 10.05 KK2995 pKa = 8.83 TRR2997 pKa = 11.84 QQHH3000 pKa = 4.95 KK3001 pKa = 9.76 CLLLFAPIVLKK3012 pKa = 10.9 DD3013 pKa = 3.51 IDD3015 pKa = 3.8 HH3016 pKa = 6.79 HH3017 pKa = 7.39 FSDD3020 pKa = 4.96 DD3021 pKa = 3.65 LKK3023 pKa = 11.09 LVKK3026 pKa = 9.72 IDD3028 pKa = 4.03 CSVLKK3033 pKa = 9.05 PTGVKK3038 pKa = 10.1 KK3039 pKa = 10.14 EE3040 pKa = 4.0 ALVVTMGSLVGAGAIARR3057 pKa = 11.84 YY3058 pKa = 8.9 KK3059 pKa = 10.96 ASLQWATKK3067 pKa = 9.11 MKK3069 pKa = 10.26 FSHH3072 pKa = 6.81 IYY3074 pKa = 10.31 LVGNQFRR3081 pKa = 11.84 ADD3083 pKa = 3.8 YY3084 pKa = 9.08 MCDD3087 pKa = 3.05 ASAVLSPTIKK3097 pKa = 9.96 HH3098 pKa = 6.17 LNRR3101 pKa = 11.84 EE3102 pKa = 4.21 GVVVEE3107 pKa = 4.06 IEE3109 pKa = 4.18 SYY3111 pKa = 10.61 LPYY3114 pKa = 10.67 VEE3116 pKa = 5.19 ICSKK3120 pKa = 10.22 DD3121 pKa = 3.67 TICIHH3126 pKa = 6.57 HH3127 pKa = 6.97 GGAGTTNWFMRR3138 pKa = 11.84 LSMRR3142 pKa = 11.84 QIILPLFNDD3151 pKa = 2.9 QWIWANCVSKK3161 pKa = 10.76 LGCAITASPITLPHH3175 pKa = 5.56 ITEE3178 pKa = 4.55 KK3179 pKa = 10.7 EE3180 pKa = 4.0 LSKK3183 pKa = 10.58 LTGKK3187 pKa = 10.09 SGSWSFEE3194 pKa = 3.33 NRR3196 pKa = 11.84 QLQGAHH3202 pKa = 7.5 GINSSRR3208 pKa = 11.84 IPDD3211 pKa = 3.46 WTKK3214 pKa = 10.74 SEE3216 pKa = 4.04 PTEE3219 pKa = 3.67 RR3220 pKa = 11.84 GYY3222 pKa = 10.72 INMLPYY3228 pKa = 10.55 LKK3230 pKa = 10.2 EE3231 pKa = 4.11 GVMSAANDD3239 pKa = 3.44 VSIKK3243 pKa = 9.86 MMNFGPLQLANEE3255 pKa = 4.28 ICALFQLADD3264 pKa = 3.82 SAFDD3268 pKa = 3.22 WHH3270 pKa = 6.82 EE3271 pKa = 4.21 KK3272 pKa = 10.61 DD3273 pKa = 3.47 NSSSGEE3279 pKa = 3.97 EE3280 pKa = 3.94 VDD3282 pKa = 5.01 PEE3284 pKa = 4.59 DD3285 pKa = 4.01 VMQEE3289 pKa = 3.78 EE3290 pKa = 5.16 GEE3292 pKa = 4.36 EE3293 pKa = 4.09 VVPDD3297 pKa = 4.25 LEE3299 pKa = 4.8 SEE3301 pKa = 4.2 EE3302 pKa = 4.24 SDD3304 pKa = 3.81 SYY3306 pKa = 11.86 VSANPEE3312 pKa = 3.31 IAASHH3317 pKa = 4.67 TTKK3320 pKa = 10.49 EE3321 pKa = 4.33 LEE3323 pKa = 4.11 EE3324 pKa = 4.45 SASQLAEE3331 pKa = 3.8 QRR3333 pKa = 11.84 SLASHH3338 pKa = 7.21 RR3339 pKa = 11.84 IEE3341 pKa = 4.7 VGDD3344 pKa = 4.32 SKK3346 pKa = 10.78 PSQASTPCVDD3356 pKa = 3.55 LVVYY3360 pKa = 7.1 QTPVVAYY3367 pKa = 10.3 SNLATEE3373 pKa = 4.7 TSTDD3377 pKa = 3.77 YY3378 pKa = 11.49 PEE3380 pKa = 4.5 MEE3382 pKa = 3.87 PTVLNEE3388 pKa = 3.98 LEE3390 pKa = 4.49 LEE3392 pKa = 4.09 RR3393 pKa = 11.84 SHH3395 pKa = 7.6 AYY3397 pKa = 10.04 RR3398 pKa = 11.84 QDD3400 pKa = 3.41 DD3401 pKa = 3.99 RR3402 pKa = 11.84 EE3403 pKa = 4.33 GTLISSLSKK3412 pKa = 10.6 PPASISNVINWRR3424 pKa = 11.84 SLVNVEE3430 pKa = 5.63 DD3431 pKa = 4.15 SRR3433 pKa = 11.84 CEE3435 pKa = 3.72 ANQICDD3441 pKa = 4.12 TIDD3444 pKa = 3.23 LATNMDD3450 pKa = 4.72 DD3451 pKa = 5.09 SPLTTTTLEE3460 pKa = 4.26 NYY3462 pKa = 7.58 HH3463 pKa = 5.68 TVYY3466 pKa = 10.92 DD3467 pKa = 4.62 PGHH3470 pKa = 6.52 NSPGTCVFDD3479 pKa = 3.85 CLSWLFPNDD3488 pKa = 3.24 KK3489 pKa = 10.66 GDD3491 pKa = 5.04 VVIQWASMLGCRR3503 pKa = 11.84 SWATKK3508 pKa = 10.35 KK3509 pKa = 10.82 DD3510 pKa = 3.29 IIVFTNLIGVSLLLRR3525 pKa = 11.84 QEE3527 pKa = 4.29 EE3528 pKa = 4.26 KK3529 pKa = 10.27 TEE3531 pKa = 3.98 LFGRR3535 pKa = 11.84 QSLSLICLNLVEE3547 pKa = 4.78 RR3548 pKa = 11.84 GGIGHH3553 pKa = 6.51 CTVIHH3558 pKa = 6.74 PDD3560 pKa = 3.04 WDD3562 pKa = 3.72 EE3563 pKa = 4.23 LLSKK3567 pKa = 10.17 RR3568 pKa = 11.84 WNASQTPFSRR3578 pKa = 11.84 IDD3580 pKa = 3.43 LKK3582 pKa = 11.3 NAARR3586 pKa = 11.84 CPKK3589 pKa = 9.79 TGMHH3593 pKa = 6.53 MIGRR3597 pKa = 11.84 VPCGSHH3603 pKa = 4.92 THH3605 pKa = 6.59 ISDD3608 pKa = 4.05 ADD3610 pKa = 3.86 LTSLSMSVSYY3620 pKa = 10.11 WSSNKK3625 pKa = 7.69 TTLDD3629 pKa = 4.13 FIEE3632 pKa = 4.73 TCAKK3636 pKa = 9.53 LTGKK3640 pKa = 9.34 PKK3642 pKa = 10.44 KK3643 pKa = 10.45 DD3644 pKa = 2.78 IAARR3648 pKa = 11.84 LQGTNWHH3655 pKa = 6.49 HH3656 pKa = 6.2 LFHH3659 pKa = 6.57 RR3660 pKa = 11.84 RR3661 pKa = 11.84 KK3662 pKa = 7.89 MQVVTTFQHH3671 pKa = 6.25 SYY3673 pKa = 11.43 KK3674 pKa = 10.7 NGCSWEE3680 pKa = 4.03 KK3681 pKa = 9.8 TGCNFKK3687 pKa = 10.78 PGDD3690 pKa = 3.86 LVTICFDD3697 pKa = 3.8 RR3698 pKa = 11.84 GCVVGVVLEE3707 pKa = 4.05 RR3708 pKa = 11.84 ARR3710 pKa = 11.84 DD3711 pKa = 3.59 YY3712 pKa = 11.06 VVQYY3716 pKa = 7.05 EE3717 pKa = 4.59 TRR3719 pKa = 11.84 TSTPLYY3725 pKa = 10.5 AISLSMNVNVKK3736 pKa = 8.59 HH3737 pKa = 4.77 TTLRR3741 pKa = 11.84 RR3742 pKa = 11.84 AVTLKK3747 pKa = 10.65 GVQEE3751 pKa = 3.87 EE3752 pKa = 4.38 AFLNVKK3758 pKa = 8.34 TMHH3761 pKa = 6.11 YY3762 pKa = 8.87 CHH3764 pKa = 7.3 SIGLRR3769 pKa = 11.84 NDD3771 pKa = 2.74 ISEE3774 pKa = 4.04 VAEE3777 pKa = 4.01 RR3778 pKa = 11.84 EE3779 pKa = 4.04 KK3780 pKa = 10.88 KK3781 pKa = 9.64 YY3782 pKa = 11.19 DD3783 pKa = 3.53 SLIVSDD3789 pKa = 4.17 FDD3791 pKa = 4.6 NRR3793 pKa = 11.84 IHH3795 pKa = 6.54 HH3796 pKa = 5.99 QFNEE3800 pKa = 3.78 KK3801 pKa = 10.52 DD3802 pKa = 2.95 ILKK3805 pKa = 9.65 YY3806 pKa = 10.62 QEE3808 pKa = 4.28 ADD3810 pKa = 3.28 AITIVSGKK3818 pKa = 9.67 SRR3820 pKa = 11.84 AVMVTWIMTEE3830 pKa = 3.43 SDD3832 pKa = 3.23 LRR3834 pKa = 11.84 LTMWHH3839 pKa = 6.27 GKK3841 pKa = 9.51 PYY3843 pKa = 10.31 IEE3845 pKa = 5.77 LKK3847 pKa = 10.18 TKK3849 pKa = 9.69 DD3850 pKa = 4.01 TILMSILDD3858 pKa = 3.84 SAGEE3862 pKa = 4.1 RR3863 pKa = 11.84 IALGNDD3869 pKa = 3.16 EE3870 pKa = 4.61 YY3871 pKa = 11.52 RR3872 pKa = 11.84 WIPEE3876 pKa = 3.9 GDD3878 pKa = 3.79 DD3879 pKa = 3.14 TRR3881 pKa = 11.84 MLRR3884 pKa = 11.84 VCDD3887 pKa = 4.4 TIPRR3891 pKa = 11.84 LQKK3894 pKa = 10.78 LLNKK3898 pKa = 9.13 TDD3900 pKa = 3.46 EE3901 pKa = 4.64 GLVEE3905 pKa = 4.73 LKK3907 pKa = 9.71 WLTMNPRR3914 pKa = 11.84 LNPIKK3919 pKa = 10.39 VVKK3922 pKa = 10.34 KK3923 pKa = 9.99 HH3924 pKa = 5.55 MLSEE3928 pKa = 4.31 GLSEE3932 pKa = 4.15 EE3933 pKa = 4.69 GEE3935 pKa = 4.0 MDD3937 pKa = 3.93 VEE3939 pKa = 4.18 EE3940 pKa = 5.24 LNLLLAVPLSEE3951 pKa = 5.41 LVILTSRR3958 pKa = 11.84 SEE3960 pKa = 3.77 IAEE3963 pKa = 3.87 WLSISRR3969 pKa = 11.84 HH3970 pKa = 3.85 MFGYY3974 pKa = 10.35 KK3975 pKa = 9.88 LDD3977 pKa = 4.85 GIYY3980 pKa = 10.46 HH3981 pKa = 6.25 SGAGGMINLAGPIVVYY3997 pKa = 10.2 KK3998 pKa = 10.68 KK3999 pKa = 10.68 KK4000 pKa = 10.48 LLPPSMTGGHH4010 pKa = 6.56 LVLDD4014 pKa = 4.62 IGDD4017 pKa = 3.66 QHH4019 pKa = 5.83 WNKK4022 pKa = 9.41 VRR4024 pKa = 11.84 EE4025 pKa = 4.2 QYY4027 pKa = 10.8 SEE4029 pKa = 3.88 NNLRR4033 pKa = 11.84 GLVKK4037 pKa = 10.5 HH4038 pKa = 5.88 GFKK4041 pKa = 9.6 VTSPEE4046 pKa = 4.06 SAQQRR4051 pKa = 11.84 ATSNMEE4057 pKa = 3.93 RR4058 pKa = 11.84 LKK4060 pKa = 10.66 QSPLYY4065 pKa = 10.12 PMLDD4069 pKa = 3.24 AVRR4072 pKa = 11.84 DD4073 pKa = 3.99 MTQGSYY4079 pKa = 11.06 SKK4081 pKa = 9.98 TPLTFTNVRR4090 pKa = 11.84 AHH4092 pKa = 6.37 EE4093 pKa = 4.15 VDD4095 pKa = 4.21 KK4096 pKa = 11.59 EE4097 pKa = 4.09 MGDD4100 pKa = 4.04 LIIPKK4105 pKa = 9.84 ILVDD4109 pKa = 3.9 TNMGWEE4115 pKa = 4.52 LEE4117 pKa = 4.38 TAHH4120 pKa = 7.79 LEE4122 pKa = 3.96 EE4123 pKa = 4.56 VPIHH4127 pKa = 5.98 VRR4129 pKa = 11.84 QMWDD4133 pKa = 3.12 EE4134 pKa = 4.1 TDD4136 pKa = 3.73 LLDD4139 pKa = 4.25 WNASYY4144 pKa = 11.16 APSNQLRR4151 pKa = 11.84 LKK4153 pKa = 7.92 TTLPTGKK4160 pKa = 9.78 RR4161 pKa = 11.84 RR4162 pKa = 11.84 TEE4164 pKa = 3.32 RR4165 pKa = 11.84 KK4166 pKa = 8.95 MIYY4169 pKa = 8.84 TKK4171 pKa = 11.0 YY4172 pKa = 9.01 PIQSRR4177 pKa = 11.84 VVLTKK4182 pKa = 10.55 AANQEE4187 pKa = 4.21 FNAVTGRR4194 pKa = 11.84 IGNASIIRR4202 pKa = 11.84 KK4203 pKa = 9.4 YY4204 pKa = 10.59 NLNIQYY4210 pKa = 9.35 EE4211 pKa = 4.64 LKK4213 pKa = 10.82 NMCRR4217 pKa = 11.84 EE4218 pKa = 4.03 LFVANWQSICAGYY4231 pKa = 9.91 QADD4234 pKa = 3.85 QVSPSPEE4241 pKa = 4.41 NILEE4245 pKa = 4.15 WLSEE4249 pKa = 4.08 KK4250 pKa = 10.42 PDD4252 pKa = 3.39 GVNIGEE4258 pKa = 4.26 EE4259 pKa = 4.0 LQSYY4263 pKa = 10.11 IEE4265 pKa = 5.51 DD4266 pKa = 3.84 GFQTHH4271 pKa = 7.73 PISDD4275 pKa = 3.99 VNVHH4279 pKa = 6.53 LKK4281 pKa = 10.94 LEE4283 pKa = 4.52 ALLKK4287 pKa = 10.0 DD4288 pKa = 3.58 QPVEE4292 pKa = 4.18 SNQALKK4298 pKa = 10.94 ARR4300 pKa = 11.84 IIVWQAKK4307 pKa = 8.18 GICAMYY4313 pKa = 10.2 SGTFIQIKK4321 pKa = 10.17 KK4322 pKa = 9.71 RR4323 pKa = 11.84 LKK4325 pKa = 9.32 KK4326 pKa = 10.29 LLRR4329 pKa = 11.84 AEE4331 pKa = 4.0 IVYY4334 pKa = 10.06 TDD4336 pKa = 3.57 GLEE4339 pKa = 3.98 PTEE4342 pKa = 3.98 IADD4345 pKa = 3.57 VVRR4348 pKa = 11.84 GIKK4351 pKa = 10.3 DD4352 pKa = 3.42 FSVLIEE4358 pKa = 5.32 DD4359 pKa = 4.52 DD4360 pKa = 3.76 LTRR4363 pKa = 11.84 QDD4365 pKa = 3.72 SQTDD4369 pKa = 3.09 SDD4371 pKa = 4.4 TINVEE4376 pKa = 3.81 FGVYY4380 pKa = 10.31 DD4381 pKa = 4.01 LLGLDD4386 pKa = 3.56 RR4387 pKa = 11.84 RR4388 pKa = 11.84 VAASWRR4394 pKa = 11.84 RR4395 pKa = 11.84 VHH4397 pKa = 6.18 EE4398 pKa = 4.08 LWRR4401 pKa = 11.84 FKK4403 pKa = 11.16 GKK4405 pKa = 9.73 DD4406 pKa = 3.35 VRR4408 pKa = 11.84 GVWQEE4413 pKa = 3.64 MRR4415 pKa = 11.84 LTGQATTALGNAVVNLAVHH4434 pKa = 6.2 WRR4436 pKa = 11.84 LVSQLGPAMKK4446 pKa = 9.61 MYY4448 pKa = 10.92 LLLGDD4453 pKa = 4.6 DD4454 pKa = 4.09 SLFFSRR4460 pKa = 11.84 TTIDD4464 pKa = 3.05 ATSLRR4469 pKa = 11.84 RR4470 pKa = 11.84 NIADD4474 pKa = 3.73 YY4475 pKa = 11.86 YY4476 pKa = 10.23 NMKK4479 pKa = 10.5 SKK4481 pKa = 11.04 AFVYY4485 pKa = 10.02 KK4486 pKa = 10.76 DD4487 pKa = 3.07 HH4488 pKa = 6.75 GTFCSMMAYY4497 pKa = 9.85 KK4498 pKa = 10.42 NPQGGAGIGPDD4509 pKa = 3.77 FVRR4512 pKa = 11.84 LKK4514 pKa = 10.77 RR4515 pKa = 11.84 RR4516 pKa = 11.84 FEE4518 pKa = 4.19 VPSGVSEE4525 pKa = 4.37 TNLTNTVARR4534 pKa = 11.84 KK4535 pKa = 8.73 MSYY4538 pKa = 11.06 CLMLGNLPIVKK4549 pKa = 10.15 KK4550 pKa = 10.55 LVEE4553 pKa = 4.32 DD4554 pKa = 3.65 MGWPIEE4560 pKa = 3.97 LQQWYY4565 pKa = 9.67 DD4566 pKa = 3.72 PSPLIDD4572 pKa = 4.66 SICDD4576 pKa = 3.4 KK4577 pKa = 11.36 YY4578 pKa = 11.74 NMSSAEE4584 pKa = 4.1 VEE4586 pKa = 4.24 SHH4588 pKa = 4.62 ITALVDD4594 pKa = 3.87 MIRR4597 pKa = 11.84 SRR4599 pKa = 11.84 TMYY4602 pKa = 10.41 EE4603 pKa = 3.13 IDD4605 pKa = 4.07 FDD4607 pKa = 5.0 VISQRR4612 pKa = 3.71
Molecular weight: 519.63 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.603
IPC2_protein 5.563
IPC_protein 5.614
Toseland 5.944
ProMoST 5.931
Dawson 5.842
Bjellqvist 5.868
Wikipedia 5.83
Rodwell 5.817
Grimsley 6.071
Solomon 5.842
Lehninger 5.83
Nozaki 6.084
DTASelect 6.275
Thurlkill 6.249
EMBOSS 6.211
Sillero 6.186
Patrickios 4.075
IPC_peptide 5.855
IPC2_peptide 6.186
IPC2.peptide.svr19 6.125
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
1
0
1
4612
4612
4612
4612.0
519.63
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
5.052 ± 0.0
2.19 ± 0.0
5.572 ± 0.0
6.808 ± 0.0
2.884 ± 0.0
5.746 ± 0.0
2.689 ± 0.0
5.551 ± 0.0
5.703 ± 0.0
10.343 ± 0.0
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.689 ± 0.0
5.03 ± 0.0
3.794 ± 0.0
3.664 ± 0.0
4.835 ± 0.0
7.871 ± 0.0
7.047 ± 0.0
7.611 ± 0.0
1.843 ± 0.0
3.036 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here