Amino acid dipepetide frequency for Filifactor alocis (strain ATCC 35896 / D40 B5) (Fusobacterium alocis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.218AlaAla: 3.218 ± 0.122
0.675AlaCys: 0.675 ± 0.04
2.903AlaAsp: 2.903 ± 0.086
3.994AlaGlu: 3.994 ± 0.095
2.764AlaPhe: 2.764 ± 0.091
3.891AlaGly: 3.891 ± 0.107
0.917AlaHis: 0.917 ± 0.038
5.305AlaIle: 5.305 ± 0.121
4.901AlaLys: 4.901 ± 0.125
5.59AlaLeu: 5.59 ± 0.122
1.959AlaMet: 1.959 ± 0.067
2.422AlaAsn: 2.422 ± 0.07
1.449AlaPro: 1.449 ± 0.062
1.632AlaGln: 1.632 ± 0.054
2.0AlaArg: 2.0 ± 0.066
3.135AlaSer: 3.135 ± 0.08
3.11AlaThr: 3.11 ± 0.091
4.336AlaVal: 4.336 ± 0.1
0.35AlaTrp: 0.35 ± 0.025
2.197AlaTyr: 2.197 ± 0.075
0.0AlaXaa: 0.0 ± 0.0
Cys
0.64CysAla: 0.64 ± 0.034
0.184CysCys: 0.184 ± 0.02
0.636CysAsp: 0.636 ± 0.034
0.683CysGlu: 0.683 ± 0.041
0.602CysPhe: 0.602 ± 0.038
0.984CysGly: 0.984 ± 0.048
0.298CysHis: 0.298 ± 0.025
0.93CysIle: 0.93 ± 0.051
0.814CysLys: 0.814 ± 0.042
0.928CysLeu: 0.928 ± 0.042
0.327CysMet: 0.327 ± 0.029
0.543CysAsn: 0.543 ± 0.036
0.449CysPro: 0.449 ± 0.034
0.331CysGln: 0.331 ± 0.028
0.41CysArg: 0.41 ± 0.028
0.828CysSer: 0.828 ± 0.043
0.526CysThr: 0.526 ± 0.034
0.743CysVal: 0.743 ± 0.042
0.079CysTrp: 0.079 ± 0.014
0.526CysTyr: 0.526 ± 0.029
0.0CysXaa: 0.0 ± 0.0
Asp
3.027AspAla: 3.027 ± 0.071
0.698AspCys: 0.698 ± 0.037
2.864AspAsp: 2.864 ± 0.085
4.59AspGlu: 4.59 ± 0.116
2.979AspPhe: 2.979 ± 0.082
3.859AspGly: 3.859 ± 0.108
0.679AspHis: 0.679 ± 0.033
5.346AspIle: 5.346 ± 0.106
4.572AspLys: 4.572 ± 0.135
4.472AspLeu: 4.472 ± 0.111
1.76AspMet: 1.76 ± 0.06
2.501AspAsn: 2.501 ± 0.086
1.248AspPro: 1.248 ± 0.049
0.938AspGln: 0.938 ± 0.046
2.236AspArg: 2.236 ± 0.064
3.57AspSer: 3.57 ± 0.087
3.054AspThr: 3.054 ± 0.099
3.93AspVal: 3.93 ± 0.085
0.491AspTrp: 0.491 ± 0.036
2.627AspTyr: 2.627 ± 0.073
0.0AspXaa: 0.0 ± 0.0
Glu
3.725GluAla: 3.725 ± 0.106
0.607GluCys: 0.607 ± 0.036
4.632GluAsp: 4.632 ± 0.121
8.833GluGlu: 8.833 ± 0.2
3.098GluPhe: 3.098 ± 0.079
4.203GluGly: 4.203 ± 0.104
1.503GluHis: 1.503 ± 0.059
6.897GluIle: 6.897 ± 0.15
8.297GluLys: 8.297 ± 0.172
7.4GluLeu: 7.4 ± 0.141
2.536GluMet: 2.536 ± 0.075
4.735GluAsn: 4.735 ± 0.108
1.64GluPro: 1.64 ± 0.062
3.383GluGln: 3.383 ± 0.103
3.263GluArg: 3.263 ± 0.095
3.655GluSer: 3.655 ± 0.101
3.715GluThr: 3.715 ± 0.091
5.201GluVal: 5.201 ± 0.108
0.545GluTrp: 0.545 ± 0.038
3.392GluTyr: 3.392 ± 0.088
0.0GluXaa: 0.0 ± 0.0
Phe
2.603PheAla: 2.603 ± 0.065
0.654PheCys: 0.654 ± 0.038
2.762PheAsp: 2.762 ± 0.067
3.321PheGlu: 3.321 ± 0.078
2.358PhePhe: 2.358 ± 0.078
2.915PheGly: 2.915 ± 0.073
0.969PheHis: 0.969 ± 0.039
3.296PheIle: 3.296 ± 0.097
2.48PheLys: 2.48 ± 0.072
4.884PheLeu: 4.884 ± 0.128
1.215PheMet: 1.215 ± 0.047
1.667PheAsn: 1.667 ± 0.062
1.365PhePro: 1.365 ± 0.049
1.58PheGln: 1.58 ± 0.062
1.721PheArg: 1.721 ± 0.058
3.3PheSer: 3.3 ± 0.097
2.168PheThr: 2.168 ± 0.055
3.539PheVal: 3.539 ± 0.094
0.404PheTrp: 0.404 ± 0.03
1.911PheTyr: 1.911 ± 0.063
0.0PheXaa: 0.0 ± 0.0
Gly
3.895GlyAla: 3.895 ± 0.111
0.75GlyCys: 0.75 ± 0.046
3.106GlyAsp: 3.106 ± 0.092
4.642GlyGlu: 4.642 ± 0.103
2.957GlyPhe: 2.957 ± 0.077
4.114GlyGly: 4.114 ± 0.148
1.048GlyHis: 1.048 ± 0.049
6.278GlyIle: 6.278 ± 0.125
5.665GlyLys: 5.665 ± 0.115
5.263GlyLeu: 5.263 ± 0.104
2.137GlyMet: 2.137 ± 0.071
3.176GlyAsn: 3.176 ± 0.113
1.035GlyPro: 1.035 ± 0.051
1.853GlyGln: 1.853 ± 0.063
2.437GlyArg: 2.437 ± 0.07
3.652GlySer: 3.652 ± 0.113
3.799GlyThr: 3.799 ± 0.096
4.47GlyVal: 4.47 ± 0.102
0.393GlyTrp: 0.393 ± 0.031
3.102GlyTyr: 3.102 ± 0.081
0.0GlyXaa: 0.0 ± 0.0
His
0.95HisAla: 0.95 ± 0.046
0.261HisCys: 0.261 ± 0.024
0.843HisAsp: 0.843 ± 0.041
1.07HisGlu: 1.07 ± 0.05
0.984HisPhe: 0.984 ± 0.057
1.095HisGly: 1.095 ± 0.051
0.559HisHis: 0.559 ± 0.032
1.629HisIle: 1.629 ± 0.064
1.114HisLys: 1.114 ± 0.048
1.656HisLeu: 1.656 ± 0.052
0.445HisMet: 0.445 ± 0.032
0.781HisAsn: 0.781 ± 0.036
0.818HisPro: 0.818 ± 0.05
0.679HisGln: 0.679 ± 0.036
0.758HisArg: 0.758 ± 0.039
1.159HisSer: 1.159 ± 0.054
0.969HisThr: 0.969 ± 0.046
0.917HisVal: 0.917 ± 0.044
0.153HisTrp: 0.153 ± 0.016
0.766HisTyr: 0.766 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
5.607IleAla: 5.607 ± 0.128
1.097IleCys: 1.097 ± 0.044
5.033IleAsp: 5.033 ± 0.104
6.261IleGlu: 6.261 ± 0.125
3.669IlePhe: 3.669 ± 0.107
5.682IleGly: 5.682 ± 0.105
1.549IleHis: 1.549 ± 0.055
6.094IleIle: 6.094 ± 0.125
5.632IleLys: 5.632 ± 0.12
8.135IleLeu: 8.135 ± 0.163
1.864IleMet: 1.864 ± 0.064
3.224IleAsn: 3.224 ± 0.081
3.478IlePro: 3.478 ± 0.089
2.963IleGln: 2.963 ± 0.073
3.433IleArg: 3.433 ± 0.078
6.152IleSer: 6.152 ± 0.119
4.375IleThr: 4.375 ± 0.101
6.245IleVal: 6.245 ± 0.131
0.507IleTrp: 0.507 ± 0.033
3.168IleTyr: 3.168 ± 0.086
0.0IleXaa: 0.0 ± 0.0
Lys
4.201LysAla: 4.201 ± 0.101
0.621LysCys: 0.621 ± 0.037
4.795LysAsp: 4.795 ± 0.13
8.8LysGlu: 8.8 ± 0.16
2.51LysPhe: 2.51 ± 0.077
4.561LysGly: 4.561 ± 0.103
1.319LysHis: 1.319 ± 0.051
6.628LysIle: 6.628 ± 0.135
8.682LysLys: 8.682 ± 0.175
6.311LysLeu: 6.311 ± 0.107
2.547LysMet: 2.547 ± 0.074
5.375LysAsn: 5.375 ± 0.112
2.046LysPro: 2.046 ± 0.086
3.336LysGln: 3.336 ± 0.1
3.514LysArg: 3.514 ± 0.069
4.301LysSer: 4.301 ± 0.091
4.358LysThr: 4.358 ± 0.093
5.077LysVal: 5.077 ± 0.123
0.545LysTrp: 0.545 ± 0.035
3.066LysTyr: 3.066 ± 0.09
0.0LysXaa: 0.0 ± 0.0
Leu
4.961LeuAla: 4.961 ± 0.098
1.209LeuCys: 1.209 ± 0.053
4.975LeuAsp: 4.975 ± 0.11
7.268LeuGlu: 7.268 ± 0.143
4.406LeuPhe: 4.406 ± 0.102
5.619LeuGly: 5.619 ± 0.115
1.598LeuHis: 1.598 ± 0.06
6.729LeuIle: 6.729 ± 0.131
7.555LeuLys: 7.555 ± 0.146
8.698LeuLeu: 8.698 ± 0.202
2.445LeuMet: 2.445 ± 0.079
4.485LeuAsn: 4.485 ± 0.108
3.056LeuPro: 3.056 ± 0.075
3.222LeuGln: 3.222 ± 0.094
3.329LeuArg: 3.329 ± 0.09
7.446LeuSer: 7.446 ± 0.144
4.497LeuThr: 4.497 ± 0.093
5.131LeuVal: 5.131 ± 0.111
0.636LeuTrp: 0.636 ± 0.04
3.404LeuTyr: 3.404 ± 0.093
0.0LeuXaa: 0.0 ± 0.0
Met
1.849MetAla: 1.849 ± 0.071
0.267MetCys: 0.267 ± 0.026
1.654MetAsp: 1.654 ± 0.066
2.346MetGlu: 2.346 ± 0.068
0.996MetPhe: 0.996 ± 0.05
1.805MetGly: 1.805 ± 0.066
0.329MetHis: 0.329 ± 0.026
2.615MetIle: 2.615 ± 0.076
3.04MetLys: 3.04 ± 0.087
2.495MetLeu: 2.495 ± 0.069
1.006MetMet: 1.006 ± 0.046
1.659MetAsn: 1.659 ± 0.054
0.911MetPro: 0.911 ± 0.045
1.021MetGln: 1.021 ± 0.04
1.126MetArg: 1.126 ± 0.048
1.805MetSer: 1.805 ± 0.061
1.48MetThr: 1.48 ± 0.054
1.808MetVal: 1.808 ± 0.071
0.168MetTrp: 0.168 ± 0.018
0.845MetTyr: 0.845 ± 0.04
0.0MetXaa: 0.0 ± 0.0
Asn
2.832AsnAla: 2.832 ± 0.065
0.538AsnCys: 0.538 ± 0.027
2.321AsnAsp: 2.321 ± 0.093
3.336AsnGlu: 3.336 ± 0.087
2.013AsnPhe: 2.013 ± 0.071
3.257AsnGly: 3.257 ± 0.094
1.081AsnHis: 1.081 ± 0.048
4.698AsnIle: 4.698 ± 0.11
3.632AsnLys: 3.632 ± 0.094
4.292AsnLeu: 4.292 ± 0.098
1.424AsnMet: 1.424 ± 0.059
2.416AsnAsn: 2.416 ± 0.072
2.147AsnPro: 2.147 ± 0.068
1.899AsnGln: 1.899 ± 0.076
2.404AsnArg: 2.404 ± 0.082
2.717AsnSer: 2.717 ± 0.076
2.584AsnThr: 2.584 ± 0.073
2.884AsnVal: 2.884 ± 0.071
0.396AsnTrp: 0.396 ± 0.029
2.126AsnTyr: 2.126 ± 0.064
0.0AsnXaa: 0.0 ± 0.0
Pro
1.547ProAla: 1.547 ± 0.057
0.358ProCys: 0.358 ± 0.028
1.776ProAsp: 1.776 ± 0.07
2.319ProGlu: 2.319 ± 0.068
1.549ProPhe: 1.549 ± 0.055
1.534ProGly: 1.534 ± 0.055
0.555ProHis: 0.555 ± 0.03
2.698ProIle: 2.698 ± 0.079
2.348ProLys: 2.348 ± 0.061
2.431ProLeu: 2.431 ± 0.079
0.853ProMet: 0.853 ± 0.045
1.646ProAsn: 1.646 ± 0.065
0.71ProPro: 0.71 ± 0.048
0.944ProGln: 0.944 ± 0.05
0.911ProArg: 0.911 ± 0.04
1.921ProSer: 1.921 ± 0.061
1.69ProThr: 1.69 ± 0.059
2.304ProVal: 2.304 ± 0.077
0.222ProTrp: 0.222 ± 0.021
1.346ProTyr: 1.346 ± 0.055
0.0ProXaa: 0.0 ± 0.0
Gln
1.855GlnAla: 1.855 ± 0.059
0.284GlnCys: 0.284 ± 0.025
1.731GlnAsp: 1.731 ± 0.073
3.224GlnGlu: 3.224 ± 0.099
1.319GlnPhe: 1.319 ± 0.052
1.948GlnGly: 1.948 ± 0.055
0.495GlnHis: 0.495 ± 0.029
2.657GlnIle: 2.657 ± 0.074
3.433GlnLys: 3.433 ± 0.103
3.027GlnLeu: 3.027 ± 0.076
0.975GlnMet: 0.975 ± 0.042
2.033GlnAsn: 2.033 ± 0.063
0.837GlnPro: 0.837 ± 0.058
1.503GlnGln: 1.503 ± 0.071
1.335GlnArg: 1.335 ± 0.047
1.882GlnSer: 1.882 ± 0.07
1.669GlnThr: 1.669 ± 0.061
1.94GlnVal: 1.94 ± 0.06
0.29GlnTrp: 0.29 ± 0.025
1.393GlnTyr: 1.393 ± 0.051
0.0GlnXaa: 0.0 ± 0.0
Arg
2.201ArgAla: 2.201 ± 0.056
0.453ArgCys: 0.453 ± 0.033
2.104ArgAsp: 2.104 ± 0.066
3.681ArgGlu: 3.681 ± 0.1
1.64ArgPhe: 1.64 ± 0.065
2.385ArgGly: 2.385 ± 0.065
0.607ArgHis: 0.607 ± 0.034
3.361ArgIle: 3.361 ± 0.082
3.508ArgLys: 3.508 ± 0.09
3.414ArgLeu: 3.414 ± 0.089
1.323ArgMet: 1.323 ± 0.049
2.071ArgAsn: 2.071 ± 0.06
1.106ArgPro: 1.106 ± 0.05
1.36ArgGln: 1.36 ± 0.05
1.656ArgArg: 1.656 ± 0.061
1.93ArgSer: 1.93 ± 0.062
1.924ArgThr: 1.924 ± 0.059
2.439ArgVal: 2.439 ± 0.069
0.333ArgTrp: 0.333 ± 0.027
1.747ArgTyr: 1.747 ± 0.062
0.0ArgXaa: 0.0 ± 0.0
Ser
3.607SerAla: 3.607 ± 0.076
0.747SerCys: 0.747 ± 0.046
3.507SerAsp: 3.507 ± 0.086
4.265SerGlu: 4.265 ± 0.104
3.317SerPhe: 3.317 ± 0.086
4.485SerGly: 4.485 ± 0.113
1.083SerHis: 1.083 ± 0.045
5.189SerIle: 5.189 ± 0.116
5.025SerLys: 5.025 ± 0.092
5.812SerLeu: 5.812 ± 0.104
1.911SerMet: 1.911 ± 0.059
2.824SerAsn: 2.824 ± 0.089
1.737SerPro: 1.737 ± 0.067
1.851SerGln: 1.851 ± 0.065
2.286SerArg: 2.286 ± 0.062
4.143SerSer: 4.143 ± 0.108
2.938SerThr: 2.938 ± 0.083
4.655SerVal: 4.655 ± 0.097
0.449SerTrp: 0.449 ± 0.03
2.634SerTyr: 2.634 ± 0.081
0.0SerXaa: 0.0 ± 0.0
Thr
3.191ThrAla: 3.191 ± 0.089
0.46ThrCys: 0.46 ± 0.029
2.982ThrAsp: 2.982 ± 0.09
3.965ThrGlu: 3.965 ± 0.101
2.325ThrPhe: 2.325 ± 0.074
3.777ThrGly: 3.777 ± 0.105
0.89ThrHis: 0.89 ± 0.044
4.309ThrIle: 4.309 ± 0.108
4.004ThrLys: 4.004 ± 0.091
4.837ThrLeu: 4.837 ± 0.103
1.454ThrMet: 1.454 ± 0.057
2.29ThrAsn: 2.29 ± 0.066
1.93ThrPro: 1.93 ± 0.072
1.456ThrGln: 1.456 ± 0.052
1.609ThrArg: 1.609 ± 0.058
2.994ThrSer: 2.994 ± 0.075
2.861ThrThr: 2.861 ± 0.084
4.33ThrVal: 4.33 ± 0.114
0.34ThrTrp: 0.34 ± 0.025
1.766ThrTyr: 1.766 ± 0.065
0.0ThrXaa: 0.0 ± 0.0
Val
4.187ValAla: 4.187 ± 0.103
0.928ValCys: 0.928 ± 0.049
3.802ValAsp: 3.802 ± 0.09
5.048ValGlu: 5.048 ± 0.102
3.174ValPhe: 3.174 ± 0.08
4.479ValGly: 4.479 ± 0.107
1.05ValHis: 1.05 ± 0.05
5.63ValIle: 5.63 ± 0.115
4.862ValLys: 4.862 ± 0.11
6.512ValLeu: 6.512 ± 0.144
1.841ValMet: 1.841 ± 0.064
2.946ValAsn: 2.946 ± 0.077
2.128ValPro: 2.128 ± 0.064
1.998ValGln: 1.998 ± 0.067
2.565ValArg: 2.565 ± 0.08
4.928ValSer: 4.928 ± 0.102
3.748ValThr: 3.748 ± 0.1
5.081ValVal: 5.081 ± 0.104
0.53ValTrp: 0.53 ± 0.033
2.547ValTyr: 2.547 ± 0.074
0.0ValXaa: 0.0 ± 0.0
Trp
0.362TrpAla: 0.362 ± 0.026
0.104TrpCys: 0.104 ± 0.014
0.455TrpAsp: 0.455 ± 0.028
0.551TrpGlu: 0.551 ± 0.035
0.329TrpPhe: 0.329 ± 0.026
0.484TrpGly: 0.484 ± 0.029
0.11TrpHis: 0.11 ± 0.015
0.708TrpIle: 0.708 ± 0.039
0.71TrpLys: 0.71 ± 0.04
0.518TrpLeu: 0.518 ± 0.031
0.251TrpMet: 0.251 ± 0.022
0.565TrpAsn: 0.565 ± 0.032
0.124TrpPro: 0.124 ± 0.018
0.22TrpGln: 0.22 ± 0.02
0.255TrpArg: 0.255 ± 0.022
0.375TrpSer: 0.375 ± 0.027
0.346TrpThr: 0.346 ± 0.034
0.369TrpVal: 0.369 ± 0.027
0.066TrpTrp: 0.066 ± 0.011
0.317TrpTyr: 0.317 ± 0.028
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.29TyrAla: 2.29 ± 0.071
0.567TyrCys: 0.567 ± 0.037
2.559TyrAsp: 2.559 ± 0.071
3.066TyrGlu: 3.066 ± 0.082
2.122TyrPhe: 2.122 ± 0.071
2.696TyrGly: 2.696 ± 0.076
0.965TyrHis: 0.965 ± 0.048
3.17TyrIle: 3.17 ± 0.077
2.319TyrLys: 2.319 ± 0.075
3.994TyrLeu: 3.994 ± 0.098
0.95TyrMet: 0.95 ± 0.039
1.638TyrAsn: 1.638 ± 0.055
1.449TyrPro: 1.449 ± 0.055
1.659TyrGln: 1.659 ± 0.053
1.996TyrArg: 1.996 ± 0.067
2.57TyrSer: 2.57 ± 0.072
1.961TyrThr: 1.961 ± 0.071
2.588TyrVal: 2.588 ± 0.071
0.321TyrTrp: 0.321 ± 0.026
1.893TyrTyr: 1.893 ± 0.065
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1616 proteins (517034 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski