Amino acid dipepetide frequency for Pangasianodon hypophthalmus (Striped catfish) (Helicophagus hypophthalmus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.791AlaAla: 5.791 ± 0.04	1.329AlaCys: 1.329 ± 0.013	3.085AlaAsp: 3.085 ± 0.018	4.897AlaGlu: 4.897 ± 0.031	2.37AlaPhe: 2.37 ± 0.017	4.165AlaGly: 4.165 ± 0.024	1.592AlaHis: 1.592 ± 0.011	2.715AlaIle: 2.715 ± 0.018	3.403AlaLys: 3.403 ± 0.024	6.7AlaLeu: 6.7 ± 0.039	1.627AlaMet: 1.627 ± 0.013	2.162AlaAsn: 2.162 ± 0.015	3.482AlaPro: 3.482 ± 0.027	3.032AlaGln: 3.032 ± 0.024	3.255AlaArg: 3.255 ± 0.018	5.509AlaSer: 5.509 ± 0.029	3.374AlaThr: 3.374 ± 0.017	4.973AlaVal: 4.973 ± 0.025	0.678AlaTrp: 0.678 ± 0.011	1.503AlaTyr: 1.503 ± 0.013	0.0AlaXaa: 0.0 ± 0.0
Cys	1.28CysAla: 1.28 ± 0.014	0.652CysCys: 0.652 ± 0.011	1.126CysAsp: 1.126 ± 0.015	1.368CysGlu: 1.368 ± 0.018	0.84CysPhe: 0.84 ± 0.01	1.499CysGly: 1.499 ± 0.02	0.657CysHis: 0.657 ± 0.009	0.956CysIle: 0.956 ± 0.011	1.201CysLys: 1.201 ± 0.014	2.102CysLeu: 2.102 ± 0.018	0.501CysMet: 0.501 ± 0.007	0.854CysAsn: 0.854 ± 0.012	1.288CysPro: 1.288 ± 0.016	1.018CysGln: 1.018 ± 0.014	1.285CysArg: 1.285 ± 0.012	2.198CysSer: 2.198 ± 0.022	1.276CysThr: 1.276 ± 0.014	1.683CysVal: 1.683 ± 0.018	0.298CysTrp: 0.298 ± 0.005	0.611CysTyr: 0.611 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	2.974AspAla: 2.974 ± 0.017	1.122AspCys: 1.122 ± 0.015	3.103AspAsp: 3.103 ± 0.035	3.96AspGlu: 3.96 ± 0.022	2.069AspPhe: 2.069 ± 0.016	3.573AspGly: 3.573 ± 0.026	1.165AspHis: 1.165 ± 0.012	2.685AspIle: 2.685 ± 0.019	2.682AspLys: 2.682 ± 0.02	4.88AspLeu: 4.88 ± 0.025	1.33AspMet: 1.33 ± 0.013	1.828AspAsn: 1.828 ± 0.016	2.747AspPro: 2.747 ± 0.018	1.908AspGln: 1.908 ± 0.015	2.581AspArg: 2.581 ± 0.018	4.522AspSer: 4.522 ± 0.025	2.779AspThr: 2.779 ± 0.017	3.382AspVal: 3.382 ± 0.021	0.657AspTrp: 0.657 ± 0.008	1.543AspTyr: 1.543 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.741GluAla: 4.741 ± 0.029	1.391GluCys: 1.391 ± 0.018	4.472GluAsp: 4.472 ± 0.028	8.1GluGlu: 8.1 ± 0.062	2.008GluPhe: 2.008 ± 0.013	4.029GluGly: 4.029 ± 0.026	1.614GluHis: 1.614 ± 0.013	3.007GluIle: 3.007 ± 0.021	5.097GluLys: 5.097 ± 0.035	6.493GluLeu: 6.493 ± 0.038	1.796GluMet: 1.796 ± 0.015	2.998GluAsn: 2.998 ± 0.019	2.952GluPro: 2.952 ± 0.025	3.381GluGln: 3.381 ± 0.025	4.567GluArg: 4.567 ± 0.031	4.697GluSer: 4.697 ± 0.026	3.519GluThr: 3.519 ± 0.024	4.366GluVal: 4.366 ± 0.025	0.705GluTrp: 0.705 ± 0.008	1.634GluTyr: 1.634 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	1.844PheAla: 1.844 ± 0.017	0.902PheCys: 0.902 ± 0.011	1.679PheAsp: 1.679 ± 0.015	1.857PheGlu: 1.857 ± 0.015	1.522PhePhe: 1.522 ± 0.014	2.131PheGly: 2.131 ± 0.017	0.996PheHis: 0.996 ± 0.009	1.883PheIle: 1.883 ± 0.016	1.763PheLys: 1.763 ± 0.013	3.753PheLeu: 3.753 ± 0.024	0.796PheMet: 0.796 ± 0.008	1.417PheAsn: 1.417 ± 0.012	1.795PhePro: 1.795 ± 0.015	1.618PheGln: 1.618 ± 0.014	1.875PheArg: 1.875 ± 0.017	3.406PheSer: 3.406 ± 0.019	2.251PheThr: 2.251 ± 0.016	2.099PheVal: 2.099 ± 0.015	0.46PheTrp: 0.46 ± 0.007	1.166PheTyr: 1.166 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	3.959GlyAla: 3.959 ± 0.027	1.233GlyCys: 1.233 ± 0.014	3.123GlyAsp: 3.123 ± 0.025	4.055GlyGlu: 4.055 ± 0.03	2.365GlyPhe: 2.365 ± 0.016	4.695GlyGly: 4.695 ± 0.032	1.666GlyHis: 1.666 ± 0.014	2.63GlyIle: 2.63 ± 0.021	3.568GlyLys: 3.568 ± 0.023	5.281GlyLeu: 5.281 ± 0.027	1.448GlyMet: 1.448 ± 0.015	2.386GlyAsn: 2.386 ± 0.017	3.124GlyPro: 3.124 ± 0.05	2.641GlyGln: 2.641 ± 0.019	3.438GlyArg: 3.438 ± 0.022	5.512GlySer: 5.512 ± 0.031	3.422GlyThr: 3.422 ± 0.023	3.98GlyVal: 3.98 ± 0.024	0.75GlyTrp: 0.75 ± 0.01	1.825GlyTyr: 1.825 ± 0.016	0.0GlyXaa: 0.0 ± 0.0
His	1.484HisAla: 1.484 ± 0.012	0.789HisCys: 0.789 ± 0.012	1.026HisAsp: 1.026 ± 0.01	1.333HisGlu: 1.333 ± 0.012	1.082HisPhe: 1.082 ± 0.01	1.603HisGly: 1.603 ± 0.014	1.054HisHis: 1.054 ± 0.016	1.3HisIle: 1.3 ± 0.011	1.339HisLys: 1.339 ± 0.012	2.658HisLeu: 2.658 ± 0.019	0.686HisMet: 0.686 ± 0.007	1.024HisAsn: 1.024 ± 0.01	1.494HisPro: 1.494 ± 0.015	1.261HisGln: 1.261 ± 0.014	1.616HisArg: 1.616 ± 0.013	2.531HisSer: 2.531 ± 0.017	1.865HisThr: 1.865 ± 0.014	1.515HisVal: 1.515 ± 0.01	0.347HisTrp: 0.347 ± 0.006	0.876HisTyr: 0.876 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	2.566IleAla: 2.566 ± 0.018	1.036IleCys: 1.036 ± 0.012	2.064IleAsp: 2.064 ± 0.017	2.477IleGlu: 2.477 ± 0.017	1.739IlePhe: 1.739 ± 0.016	2.267IleGly: 2.267 ± 0.017	1.25IleHis: 1.25 ± 0.011	2.43IleIle: 2.43 ± 0.02	2.598IleLys: 2.598 ± 0.021	4.228IleLeu: 4.228 ± 0.022	1.085IleMet: 1.085 ± 0.01	1.941IleAsn: 1.941 ± 0.015	2.476IlePro: 2.476 ± 0.016	2.187IleGln: 2.187 ± 0.016	2.431IleArg: 2.431 ± 0.016	3.987IleSer: 3.987 ± 0.024	2.947IleThr: 2.947 ± 0.022	2.545IleVal: 2.545 ± 0.017	0.479IleTrp: 0.479 ± 0.007	1.355IleTyr: 1.355 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	3.83LysAla: 3.83 ± 0.021	1.091LysCys: 1.091 ± 0.012	3.273LysAsp: 3.273 ± 0.022	4.937LysGlu: 4.937 ± 0.036	1.583LysPhe: 1.583 ± 0.013	3.259LysGly: 3.259 ± 0.032	1.487LysHis: 1.487 ± 0.014	2.551LysIle: 2.551 ± 0.019	4.64LysLys: 4.64 ± 0.042	5.048LysLeu: 5.048 ± 0.027	1.499LysMet: 1.499 ± 0.012	2.353LysAsn: 2.353 ± 0.016	3.027LysPro: 3.027 ± 0.028	2.716LysGln: 2.716 ± 0.018	3.561LysArg: 3.561 ± 0.019	4.086LysSer: 4.086 ± 0.024	3.184LysThr: 3.184 ± 0.021	3.48LysVal: 3.48 ± 0.025	0.599LysTrp: 0.599 ± 0.009	1.489LysTyr: 1.489 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.04LeuAla: 6.04 ± 0.034	2.236LeuCys: 2.236 ± 0.019	4.741LeuAsp: 4.741 ± 0.025	6.571LeuGlu: 6.571 ± 0.04	3.257LeuPhe: 3.257 ± 0.023	4.989LeuGly: 4.989 ± 0.026	2.818LeuHis: 2.818 ± 0.018	3.843LeuIle: 3.843 ± 0.023	5.737LeuLys: 5.737 ± 0.033	9.908LeuLeu: 9.908 ± 0.059	2.131LeuMet: 2.131 ± 0.015	3.692LeuAsn: 3.692 ± 0.018	5.167LeuPro: 5.167 ± 0.027	5.57LeuGln: 5.57 ± 0.034	5.66LeuArg: 5.66 ± 0.025	8.338LeuSer: 8.338 ± 0.04	5.118LeuThr: 5.118 ± 0.027	5.284LeuVal: 5.284 ± 0.031	1.052LeuTrp: 1.052 ± 0.011	2.599LeuTyr: 2.599 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	2.009MetAla: 2.009 ± 0.014	0.502MetCys: 0.502 ± 0.007	1.452MetAsp: 1.452 ± 0.012	2.094MetGlu: 2.094 ± 0.016	0.833MetPhe: 0.833 ± 0.01	1.37MetGly: 1.37 ± 0.015	0.507MetHis: 0.507 ± 0.007	0.897MetIle: 0.897 ± 0.008	1.538MetLys: 1.538 ± 0.014	2.113MetLeu: 2.113 ± 0.015	0.739MetMet: 0.739 ± 0.009	0.954MetAsn: 0.954 ± 0.009	1.153MetPro: 1.153 ± 0.014	1.042MetGln: 1.042 ± 0.011	1.227MetArg: 1.227 ± 0.01	1.902MetSer: 1.902 ± 0.012	1.244MetThr: 1.244 ± 0.011	1.484MetVal: 1.484 ± 0.012	0.267MetTrp: 0.267 ± 0.005	0.609MetTyr: 0.609 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.232AsnAla: 2.232 ± 0.013	0.864AsnCys: 0.864 ± 0.01	1.686AsnAsp: 1.686 ± 0.015	2.241AsnGlu: 2.241 ± 0.014	1.378AsnPhe: 1.378 ± 0.011	2.752AsnGly: 2.752 ± 0.022	0.985AsnHis: 0.985 ± 0.01	2.136AsnIle: 2.136 ± 0.015	2.23AsnLys: 2.23 ± 0.016	3.557AsnLeu: 3.557 ± 0.022	1.064AsnMet: 1.064 ± 0.009	1.718AsnAsn: 1.718 ± 0.019	2.235AsnPro: 2.235 ± 0.016	1.741AsnGln: 1.741 ± 0.015	2.002AsnArg: 2.002 ± 0.016	3.338AsnSer: 3.338 ± 0.018	2.408AsnThr: 2.408 ± 0.016	2.37AsnVal: 2.37 ± 0.016	0.447AsnTrp: 0.447 ± 0.007	1.115AsnTyr: 1.115 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	4.038ProAla: 4.038 ± 0.028	1.103ProCys: 1.103 ± 0.013	2.816ProAsp: 2.816 ± 0.02	3.859ProGlu: 3.859 ± 0.023	1.729ProPhe: 1.729 ± 0.016	4.016ProGly: 4.016 ± 0.067	1.472ProHis: 1.472 ± 0.015	1.902ProIle: 1.902 ± 0.017	2.671ProLys: 2.671 ± 0.023	4.724ProLeu: 4.724 ± 0.025	1.032ProMet: 1.032 ± 0.013	1.912ProAsn: 1.912 ± 0.016	5.1ProPro: 5.1 ± 0.052	2.548ProGln: 2.548 ± 0.023	2.706ProArg: 2.706 ± 0.021	5.404ProSer: 5.404 ± 0.037	2.988ProThr: 2.988 ± 0.024	3.843ProVal: 3.843 ± 0.023	0.535ProTrp: 0.535 ± 0.008	1.403ProTyr: 1.403 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.201GlnAla: 3.201 ± 0.023	1.076GlnCys: 1.076 ± 0.015	2.387GlnAsp: 2.387 ± 0.016	3.695GlnGlu: 3.695 ± 0.027	1.31GlnPhe: 1.31 ± 0.013	2.6GlnGly: 2.6 ± 0.022	1.442GlnHis: 1.442 ± 0.013	1.986GlnIle: 1.986 ± 0.012	2.802GlnLys: 2.802 ± 0.021	4.486GlnLeu: 4.486 ± 0.029	1.137GlnMet: 1.137 ± 0.011	1.944GlnAsn: 1.944 ± 0.015	2.474GlnPro: 2.474 ± 0.02	3.252GlnGln: 3.252 ± 0.04	3.084GlnArg: 3.084 ± 0.019	3.608GlnSer: 3.608 ± 0.023	2.549GlnThr: 2.549 ± 0.018	2.726GlnVal: 2.726 ± 0.02	0.551GlnTrp: 0.551 ± 0.008	1.24GlnTyr: 1.24 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	3.622ArgAla: 3.622 ± 0.02	1.27ArgCys: 1.27 ± 0.015	2.919ArgAsp: 2.919 ± 0.017	4.135ArgGlu: 4.135 ± 0.03	1.958ArgPhe: 1.958 ± 0.014	3.326ArgGly: 3.326 ± 0.026	1.571ArgHis: 1.571 ± 0.012	2.395ArgIle: 2.395 ± 0.016	3.677ArgLys: 3.677 ± 0.022	5.234ArgLeu: 5.234 ± 0.03	1.36ArgMet: 1.36 ± 0.011	2.184ArgAsn: 2.184 ± 0.016	2.808ArgPro: 2.808 ± 0.023	2.58ArgGln: 2.58 ± 0.019	4.381ArgArg: 4.381 ± 0.033	4.546ArgSer: 4.546 ± 0.025	2.892ArgThr: 2.892 ± 0.017	3.42ArgVal: 3.42 ± 0.024	0.669ArgTrp: 0.669 ± 0.008	1.529ArgTyr: 1.529 ± 0.013	0.0ArgXaa: 0.0 ± 0.0
Ser	5.821SerAla: 5.821 ± 0.032	1.973SerCys: 1.973 ± 0.016	4.421SerAsp: 4.421 ± 0.024	5.371SerGlu: 5.371 ± 0.028	3.012SerPhe: 3.012 ± 0.021	5.578SerGly: 5.578 ± 0.03	2.276SerHis: 2.276 ± 0.017	3.4SerIle: 3.4 ± 0.018	4.153SerLys: 4.153 ± 0.025	8.06SerLeu: 8.06 ± 0.039	1.909SerMet: 1.909 ± 0.014	3.039SerAsn: 3.039 ± 0.018	5.661SerPro: 5.661 ± 0.05	3.885SerGln: 3.885 ± 0.026	4.557SerArg: 4.557 ± 0.03	10.573SerSer: 10.573 ± 0.07	5.108SerThr: 5.108 ± 0.033	5.752SerVal: 5.752 ± 0.026	0.981SerTrp: 0.981 ± 0.01	2.157SerTyr: 2.157 ± 0.014	0.0SerXaa: 0.0 ± 0.0
Thr	4.066ThrAla: 4.066 ± 0.021	1.34ThrCys: 1.34 ± 0.018	2.957ThrAsp: 2.957 ± 0.019	4.031ThrGlu: 4.031 ± 0.026	2.038ThrPhe: 2.038 ± 0.014	3.64ThrGly: 3.64 ± 0.021	1.632ThrHis: 1.632 ± 0.014	2.395ThrIle: 2.395 ± 0.017	2.687ThrLys: 2.687 ± 0.019	5.496ThrLeu: 5.496 ± 0.028	1.195ThrMet: 1.195 ± 0.009	1.933ThrAsn: 1.933 ± 0.013	3.664ThrPro: 3.664 ± 0.026	2.517ThrGln: 2.517 ± 0.016	2.552ThrArg: 2.552 ± 0.017	4.879ThrSer: 4.879 ± 0.031	3.313ThrThr: 3.313 ± 0.033	4.186ThrVal: 4.186 ± 0.028	0.67ThrTrp: 0.67 ± 0.011	1.436ThrTyr: 1.436 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	4.036ValAla: 4.036 ± 0.022	1.81ValCys: 1.81 ± 0.017	3.161ValAsp: 3.161 ± 0.018	4.206ValGlu: 4.206 ± 0.024	2.532ValPhe: 2.532 ± 0.02	3.343ValGly: 3.343 ± 0.021	1.619ValHis: 1.619 ± 0.013	2.964ValIle: 2.964 ± 0.019	3.684ValLys: 3.684 ± 0.023	6.352ValLeu: 6.352 ± 0.032	1.576ValMet: 1.576 ± 0.014	2.471ValAsn: 2.471 ± 0.019	3.433ValPro: 3.433 ± 0.02	2.958ValGln: 2.958 ± 0.019	3.263ValArg: 3.263 ± 0.021	5.35ValSer: 5.35 ± 0.03	3.961ValThr: 3.961 ± 0.032	4.202ValVal: 4.202 ± 0.025	0.779ValTrp: 0.779 ± 0.009	1.85ValTyr: 1.85 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	0.679TrpAla: 0.679 ± 0.01	0.257TrpCys: 0.257 ± 0.005	0.633TrpAsp: 0.633 ± 0.009	0.743TrpGlu: 0.743 ± 0.009	0.437TrpPhe: 0.437 ± 0.006	0.599TrpGly: 0.599 ± 0.01	0.287TrpHis: 0.287 ± 0.005	0.565TrpIle: 0.565 ± 0.008	0.742TrpLys: 0.742 ± 0.008	1.143TrpLeu: 1.143 ± 0.013	0.341TrpMet: 0.341 ± 0.006	0.513TrpAsn: 0.513 ± 0.007	0.437TrpPro: 0.437 ± 0.007	0.476TrpGln: 0.476 ± 0.008	0.758TrpArg: 0.758 ± 0.009	0.944TrpSer: 0.944 ± 0.009	0.706TrpThr: 0.706 ± 0.009	0.681TrpVal: 0.681 ± 0.008	0.191TrpTrp: 0.191 ± 0.005	0.349TrpTyr: 0.349 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.431TyrAla: 1.431 ± 0.012	0.717TyrCys: 0.717 ± 0.008	1.366TyrAsp: 1.366 ± 0.011	1.635TyrGlu: 1.635 ± 0.013	1.154TyrPhe: 1.154 ± 0.011	1.669TyrGly: 1.669 ± 0.015	0.794TyrHis: 0.794 ± 0.01	1.445TyrIle: 1.445 ± 0.015	1.48TyrLys: 1.48 ± 0.015	2.535TyrLeu: 2.535 ± 0.016	0.681TyrMet: 0.681 ± 0.009	1.175TyrAsn: 1.175 ± 0.012	1.284TyrPro: 1.284 ± 0.012	1.219TyrGln: 1.219 ± 0.01	1.676TyrArg: 1.676 ± 0.015	2.359TyrSer: 2.359 ± 0.014	1.723TyrThr: 1.723 ± 0.017	1.577TyrVal: 1.577 ± 0.015	0.368TyrTrp: 0.368 ± 0.007	0.986TyrTyr: 0.986 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 21221 proteins (12012490 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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