Amino acid dipepetide frequency for Carnobacterium inhibens subsp. gilichinskyi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.181AlaAla: 5.181 ± 0.123	0.441AlaCys: 0.441 ± 0.026	3.513AlaAsp: 3.513 ± 0.076	4.785AlaGlu: 4.785 ± 0.1	3.02AlaPhe: 3.02 ± 0.075	4.758AlaGly: 4.758 ± 0.11	1.066AlaHis: 1.066 ± 0.039	6.044AlaIle: 6.044 ± 0.097	4.532AlaLys: 4.532 ± 0.095	6.866AlaLeu: 6.866 ± 0.112	1.931AlaMet: 1.931 ± 0.051	2.859AlaAsn: 2.859 ± 0.068	1.806AlaPro: 1.806 ± 0.056	2.348AlaGln: 2.348 ± 0.067	2.306AlaArg: 2.306 ± 0.064	4.002AlaSer: 4.002 ± 0.077	4.03AlaThr: 4.03 ± 0.091	5.007AlaVal: 5.007 ± 0.092	0.482AlaTrp: 0.482 ± 0.027	2.285AlaTyr: 2.285 ± 0.063	0.0AlaXaa: 0.0 ± 0.0
Cys	0.336CysAla: 0.336 ± 0.024	0.059CysCys: 0.059 ± 0.009	0.303CysAsp: 0.303 ± 0.022	0.319CysGlu: 0.319 ± 0.022	0.267CysPhe: 0.267 ± 0.02	0.515CysGly: 0.515 ± 0.031	0.148CysHis: 0.148 ± 0.017	0.398CysIle: 0.398 ± 0.026	0.234CysLys: 0.234 ± 0.02	0.583CysLeu: 0.583 ± 0.034	0.125CysMet: 0.125 ± 0.014	0.217CysAsn: 0.217 ± 0.02	0.222CysPro: 0.222 ± 0.023	0.213CysGln: 0.213 ± 0.016	0.181CysArg: 0.181 ± 0.017	0.392CysSer: 0.392 ± 0.024	0.282CysThr: 0.282 ± 0.023	0.297CysVal: 0.297 ± 0.023	0.046CysTrp: 0.046 ± 0.008	0.191CysTyr: 0.191 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.52AspAla: 3.52 ± 0.088	0.292AspCys: 0.292 ± 0.021	2.655AspAsp: 2.655 ± 0.079	4.626AspGlu: 4.626 ± 0.092	2.749AspPhe: 2.749 ± 0.07	3.287AspGly: 3.287 ± 0.068	1.056AspHis: 1.056 ± 0.045	4.388AspIle: 4.388 ± 0.079	3.525AspLys: 3.525 ± 0.065	5.111AspLeu: 5.111 ± 0.105	1.463AspMet: 1.463 ± 0.044	2.156AspAsn: 2.156 ± 0.06	1.949AspPro: 1.949 ± 0.05	2.087AspGln: 2.087 ± 0.053	1.918AspArg: 1.918 ± 0.057	3.302AspSer: 3.302 ± 0.07	3.116AspThr: 3.116 ± 0.073	3.816AspVal: 3.816 ± 0.078	0.538AspTrp: 0.538 ± 0.031	2.62AspTyr: 2.62 ± 0.068	0.0AspXaa: 0.0 ± 0.0
Glu	5.474GluAla: 5.474 ± 0.105	0.267GluCys: 0.267 ± 0.021	4.231GluAsp: 4.231 ± 0.091	7.409GluGlu: 7.409 ± 0.128	2.597GluPhe: 2.597 ± 0.059	4.172GluGly: 4.172 ± 0.083	1.213GluHis: 1.213 ± 0.045	5.81GluIle: 5.81 ± 0.094	6.854GluLys: 6.854 ± 0.117	7.669GluLeu: 7.669 ± 0.118	2.341GluMet: 2.341 ± 0.056	4.479GluAsn: 4.479 ± 0.076	2.049GluPro: 2.049 ± 0.061	3.368GluGln: 3.368 ± 0.088	3.078GluArg: 3.078 ± 0.071	4.341GluSer: 4.341 ± 0.093	4.855GluThr: 4.855 ± 0.086	5.29GluVal: 5.29 ± 0.086	0.724GluTrp: 0.724 ± 0.034	2.278GluTyr: 2.278 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	2.597PheAla: 2.597 ± 0.075	0.311PheCys: 0.311 ± 0.022	2.67PheAsp: 2.67 ± 0.067	2.981PheGlu: 2.981 ± 0.063	2.328PhePhe: 2.328 ± 0.066	3.1PheGly: 3.1 ± 0.073	0.742PheHis: 0.742 ± 0.034	3.761PheIle: 3.761 ± 0.083	2.548PheLys: 2.548 ± 0.07	4.262PheLeu: 4.262 ± 0.093	1.066PheMet: 1.066 ± 0.04	2.259PheAsn: 2.259 ± 0.064	1.541PhePro: 1.541 ± 0.046	1.501PheGln: 1.501 ± 0.048	1.285PheArg: 1.285 ± 0.042	3.525PheSer: 3.525 ± 0.08	2.529PheThr: 2.529 ± 0.058	2.945PheVal: 2.945 ± 0.066	0.445PheTrp: 0.445 ± 0.025	1.798PheTyr: 1.798 ± 0.056	0.0PheXaa: 0.0 ± 0.0
Gly	4.264GlyAla: 4.264 ± 0.096	0.408GlyCys: 0.408 ± 0.023	3.039GlyAsp: 3.039 ± 0.08	4.362GlyGlu: 4.362 ± 0.085	3.124GlyPhe: 3.124 ± 0.082	4.349GlyGly: 4.349 ± 0.127	1.25GlyHis: 1.25 ± 0.045	5.888GlyIle: 5.888 ± 0.093	4.894GlyLys: 4.894 ± 0.096	6.267GlyLeu: 6.267 ± 0.1	1.986GlyMet: 1.986 ± 0.051	2.871GlyAsn: 2.871 ± 0.068	1.435GlyPro: 1.435 ± 0.061	2.047GlyGln: 2.047 ± 0.061	2.281GlyArg: 2.281 ± 0.061	4.07GlySer: 4.07 ± 0.092	4.352GlyThr: 4.352 ± 0.097	4.485GlyVal: 4.485 ± 0.097	0.624GlyTrp: 0.624 ± 0.035	2.765GlyTyr: 2.765 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	1.05HisAla: 1.05 ± 0.044	0.119HisCys: 0.119 ± 0.012	0.88HisAsp: 0.88 ± 0.037	1.242HisGlu: 1.242 ± 0.042	0.969HisPhe: 0.969 ± 0.041	1.093HisGly: 1.093 ± 0.042	0.545HisHis: 0.545 ± 0.032	1.281HisIle: 1.281 ± 0.044	0.909HisLys: 0.909 ± 0.037	1.914HisLeu: 1.914 ± 0.055	0.46HisMet: 0.46 ± 0.023	0.676HisAsn: 0.676 ± 0.035	0.968HisPro: 0.968 ± 0.045	0.734HisGln: 0.734 ± 0.033	0.699HisArg: 0.699 ± 0.034	1.112HisSer: 1.112 ± 0.048	1.024HisThr: 1.024 ± 0.039	1.078HisVal: 1.078 ± 0.036	0.141HisTrp: 0.141 ± 0.016	0.952HisTyr: 0.952 ± 0.038	0.0HisXaa: 0.0 ± 0.0
Ile	5.922IleAla: 5.922 ± 0.111	0.557IleCys: 0.557 ± 0.031	4.804IleAsp: 4.804 ± 0.087	6.528IleGlu: 6.528 ± 0.111	3.316IlePhe: 3.316 ± 0.092	5.822IleGly: 5.822 ± 0.105	1.423IleHis: 1.423 ± 0.05	6.393IleIle: 6.393 ± 0.122	5.264IleLys: 5.264 ± 0.095	7.249IleLeu: 7.249 ± 0.105	1.779IleMet: 1.779 ± 0.054	3.531IleAsn: 3.531 ± 0.072	3.235IlePro: 3.235 ± 0.065	3.331IleGln: 3.331 ± 0.065	2.796IleArg: 2.796 ± 0.066	5.18IleSer: 5.18 ± 0.1	4.562IleThr: 4.562 ± 0.087	5.737IleVal: 5.737 ± 0.099	0.621IleTrp: 0.621 ± 0.032	2.647IleTyr: 2.647 ± 0.068	0.0IleXaa: 0.0 ± 0.0
Lys	4.616LysAla: 4.616 ± 0.094	0.206LysCys: 0.206 ± 0.02	4.102LysAsp: 4.102 ± 0.08	7.587LysGlu: 7.587 ± 0.12	1.94LysPhe: 1.94 ± 0.058	4.218LysGly: 4.218 ± 0.081	1.107LysHis: 1.107 ± 0.047	5.227LysIle: 5.227 ± 0.082	6.791LysLys: 6.791 ± 0.126	5.772LysLeu: 5.772 ± 0.087	2.282LysMet: 2.282 ± 0.055	4.261LysAsn: 4.261 ± 0.084	2.005LysPro: 2.005 ± 0.056	3.014LysGln: 3.014 ± 0.077	3.024LysArg: 3.024 ± 0.076	3.727LysSer: 3.727 ± 0.084	3.976LysThr: 3.976 ± 0.089	4.647LysVal: 4.647 ± 0.091	0.706LysTrp: 0.706 ± 0.034	2.15LysTyr: 2.15 ± 0.062	0.0LysXaa: 0.0 ± 0.0
Leu	7.141LeuAla: 7.141 ± 0.107	0.473LeuCys: 0.473 ± 0.027	5.218LeuAsp: 5.218 ± 0.089	6.929LeuGlu: 6.929 ± 0.114	4.767LeuPhe: 4.767 ± 0.111	5.997LeuGly: 5.997 ± 0.102	1.557LeuHis: 1.557 ± 0.055	7.593LeuIle: 7.593 ± 0.111	6.831LeuLys: 6.831 ± 0.11	9.451LeuLeu: 9.451 ± 0.157	2.666LeuMet: 2.666 ± 0.064	5.017LeuAsn: 5.017 ± 0.091	3.581LeuPro: 3.581 ± 0.071	3.115LeuGln: 3.115 ± 0.072	3.052LeuArg: 3.052 ± 0.075	7.077LeuSer: 7.077 ± 0.1	6.359LeuThr: 6.359 ± 0.108	6.365LeuVal: 6.365 ± 0.117	0.661LeuTrp: 0.661 ± 0.034	3.108LeuTyr: 3.108 ± 0.084	0.0LeuXaa: 0.0 ± 0.0
Met	1.853MetAla: 1.853 ± 0.055	0.097MetCys: 0.097 ± 0.01	1.636MetAsp: 1.636 ± 0.05	2.009MetGlu: 2.009 ± 0.055	0.827MetPhe: 0.827 ± 0.037	1.732MetGly: 1.732 ± 0.051	0.436MetHis: 0.436 ± 0.029	2.244MetIle: 2.244 ± 0.053	2.279MetLys: 2.279 ± 0.056	2.265MetLeu: 2.265 ± 0.06	0.839MetMet: 0.839 ± 0.037	1.626MetAsn: 1.626 ± 0.043	0.965MetPro: 0.965 ± 0.039	0.919MetGln: 0.919 ± 0.037	0.978MetArg: 0.978 ± 0.038	1.831MetSer: 1.831 ± 0.047	1.718MetThr: 1.718 ± 0.041	1.87MetVal: 1.87 ± 0.052	0.167MetTrp: 0.167 ± 0.016	0.775MetTyr: 0.775 ± 0.037	0.0MetXaa: 0.0 ± 0.0
Asn	2.868AsnAla: 2.868 ± 0.066	0.303AsnCys: 0.303 ± 0.022	2.661AsnAsp: 2.661 ± 0.06	4.111AsnGlu: 4.111 ± 0.08	1.975AsnPhe: 1.975 ± 0.054	3.545AsnGly: 3.545 ± 0.079	1.091AsnHis: 1.091 ± 0.04	3.39AsnIle: 3.39 ± 0.071	3.349AsnLys: 3.349 ± 0.084	4.366AsnLeu: 4.366 ± 0.091	1.325AsnMet: 1.325 ± 0.039	2.291AsnAsn: 2.291 ± 0.055	2.05AsnPro: 2.05 ± 0.047	2.519AsnGln: 2.519 ± 0.064	1.892AsnArg: 1.892 ± 0.049	2.691AsnSer: 2.691 ± 0.066	2.444AsnThr: 2.444 ± 0.058	2.956AsnVal: 2.956 ± 0.071	0.538AsnTrp: 0.538 ± 0.027	2.061AsnTyr: 2.061 ± 0.053	0.0AsnXaa: 0.0 ± 0.0
Pro	2.041ProAla: 2.041 ± 0.061	0.153ProCys: 0.153 ± 0.015	1.848ProAsp: 1.848 ± 0.053	3.059ProGlu: 3.059 ± 0.083	1.714ProPhe: 1.714 ± 0.059	1.922ProGly: 1.922 ± 0.061	0.582ProHis: 0.582 ± 0.03	2.864ProIle: 2.864 ± 0.058	2.131ProLys: 2.131 ± 0.055	3.171ProLeu: 3.171 ± 0.077	0.773ProMet: 0.773 ± 0.034	1.621ProAsn: 1.621 ± 0.044	0.652ProPro: 0.652 ± 0.034	1.081ProGln: 1.081 ± 0.041	0.933ProArg: 0.933 ± 0.039	2.062ProSer: 2.062 ± 0.056	2.091ProThr: 2.091 ± 0.051	2.523ProVal: 2.523 ± 0.067	0.256ProTrp: 0.256 ± 0.02	1.322ProTyr: 1.322 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	2.676GlnAla: 2.676 ± 0.057	0.131GlnCys: 0.131 ± 0.015	1.789GlnAsp: 1.789 ± 0.053	3.124GlnGlu: 3.124 ± 0.074	1.701GlnPhe: 1.701 ± 0.05	1.981GlnGly: 1.981 ± 0.054	0.68GlnHis: 0.68 ± 0.034	2.638GlnIle: 2.638 ± 0.061	2.929GlnLys: 2.929 ± 0.073	4.474GlnLeu: 4.474 ± 0.087	1.153GlnMet: 1.153 ± 0.044	1.764GlnAsn: 1.764 ± 0.054	1.137GlnPro: 1.137 ± 0.042	1.828GlnGln: 1.828 ± 0.061	1.359GlnArg: 1.359 ± 0.05	2.213GlnSer: 2.213 ± 0.063	2.376GlnThr: 2.376 ± 0.061	2.56GlnVal: 2.56 ± 0.057	0.316GlnTrp: 0.316 ± 0.024	1.256GlnTyr: 1.256 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	2.008ArgAla: 2.008 ± 0.057	0.194ArgCys: 0.194 ± 0.016	1.79ArgAsp: 1.79 ± 0.048	2.633ArgGlu: 2.633 ± 0.074	1.673ArgPhe: 1.673 ± 0.053	1.964ArgGly: 1.964 ± 0.063	0.617ArgHis: 0.617 ± 0.025	2.995ArgIle: 2.995 ± 0.07	2.83ArgLys: 2.83 ± 0.074	3.512ArgLeu: 3.512 ± 0.075	1.125ArgMet: 1.125 ± 0.044	1.853ArgAsn: 1.853 ± 0.058	1.153ArgPro: 1.153 ± 0.045	1.304ArgGln: 1.304 ± 0.045	1.526ArgArg: 1.526 ± 0.052	2.061ArgSer: 2.061 ± 0.051	1.977ArgThr: 1.977 ± 0.05	2.447ArgVal: 2.447 ± 0.069	0.257ArgTrp: 0.257 ± 0.019	1.52ArgTyr: 1.52 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	3.845SerAla: 3.845 ± 0.086	0.326SerCys: 0.326 ± 0.024	3.25SerAsp: 3.25 ± 0.068	4.544SerGlu: 4.544 ± 0.095	3.221SerPhe: 3.221 ± 0.077	4.55SerGly: 4.55 ± 0.092	1.09SerHis: 1.09 ± 0.043	5.537SerIle: 5.537 ± 0.104	4.334SerLys: 4.334 ± 0.082	6.512SerLeu: 6.512 ± 0.11	1.564SerMet: 1.564 ± 0.041	2.882SerAsn: 2.882 ± 0.069	1.828SerPro: 1.828 ± 0.051	2.191SerGln: 2.191 ± 0.054	2.127SerArg: 2.127 ± 0.059	4.57SerSer: 4.57 ± 0.126	3.672SerThr: 3.672 ± 0.082	4.363SerVal: 4.363 ± 0.068	0.568SerTrp: 0.568 ± 0.031	2.482SerTyr: 2.482 ± 0.066	0.0SerXaa: 0.0 ± 0.0
Thr	4.197ThrAla: 4.197 ± 0.081	0.267ThrCys: 0.267 ± 0.023	3.319ThrAsp: 3.319 ± 0.079	4.053ThrGlu: 4.053 ± 0.087	2.743ThrPhe: 2.743 ± 0.065	4.277ThrGly: 4.277 ± 0.085	1.126ThrHis: 1.126 ± 0.034	5.513ThrIle: 5.513 ± 0.091	4.039ThrLys: 4.039 ± 0.079	5.923ThrLeu: 5.923 ± 0.101	1.31ThrMet: 1.31 ± 0.044	2.864ThrAsn: 2.864 ± 0.072	2.2ThrPro: 2.2 ± 0.066	1.969ThrGln: 1.969 ± 0.056	1.871ThrArg: 1.871 ± 0.053	3.689ThrSer: 3.689 ± 0.092	3.714ThrThr: 3.714 ± 0.09	4.579ThrVal: 4.579 ± 0.09	0.404ThrTrp: 0.404 ± 0.025	2.109ThrTyr: 2.109 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	4.966ValAla: 4.966 ± 0.103	0.452ValCys: 0.452 ± 0.026	3.851ValAsp: 3.851 ± 0.08	5.114ValGlu: 5.114 ± 0.103	3.017ValPhe: 3.017 ± 0.075	4.541ValGly: 4.541 ± 0.099	1.173ValHis: 1.173 ± 0.045	5.554ValIle: 5.554 ± 0.096	4.405ValLys: 4.405 ± 0.079	6.828ValLeu: 6.828 ± 0.094	1.843ValMet: 1.843 ± 0.048	3.062ValAsn: 3.062 ± 0.07	2.441ValPro: 2.441 ± 0.059	2.347ValGln: 2.347 ± 0.055	2.25ValArg: 2.25 ± 0.072	4.645ValSer: 4.645 ± 0.08	4.471ValThr: 4.471 ± 0.09	5.061ValVal: 5.061 ± 0.113	0.495ValTrp: 0.495 ± 0.029	2.182ValTyr: 2.182 ± 0.056	0.0ValXaa: 0.0 ± 0.0
Trp	0.439TrpAla: 0.439 ± 0.026	0.056TrpCys: 0.056 ± 0.01	0.488TrpAsp: 0.488 ± 0.03	0.582TrpGlu: 0.582 ± 0.027	0.385TrpPhe: 0.385 ± 0.027	0.526TrpGly: 0.526 ± 0.031	0.162TrpHis: 0.162 ± 0.013	0.684TrpIle: 0.684 ± 0.036	0.617TrpLys: 0.617 ± 0.032	0.922TrpLeu: 0.922 ± 0.036	0.242TrpMet: 0.242 ± 0.02	0.47TrpAsn: 0.47 ± 0.03	0.189TrpPro: 0.189 ± 0.016	0.375TrpGln: 0.375 ± 0.021	0.322TrpArg: 0.322 ± 0.023	0.582TrpSer: 0.582 ± 0.029	0.489TrpThr: 0.489 ± 0.031	0.51TrpVal: 0.51 ± 0.027	0.103TrpTrp: 0.103 ± 0.012	0.319TrpTyr: 0.319 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.269TyrAla: 2.269 ± 0.06	0.216TyrCys: 0.216 ± 0.02	2.128TyrAsp: 2.128 ± 0.051	2.503TyrGlu: 2.503 ± 0.058	1.861TyrPhe: 1.861 ± 0.058	2.41TyrGly: 2.41 ± 0.065	0.78TyrHis: 0.78 ± 0.037	2.494TyrIle: 2.494 ± 0.077	2.065TyrLys: 2.065 ± 0.06	3.841TyrLeu: 3.841 ± 0.085	0.795TyrMet: 0.795 ± 0.03	1.665TyrAsn: 1.665 ± 0.053	1.392TyrPro: 1.392 ± 0.046	1.79TyrGln: 1.79 ± 0.055	1.561TyrArg: 1.561 ± 0.049	2.384TyrSer: 2.384 ± 0.057	2.132TyrThr: 2.132 ± 0.053	2.165TyrVal: 2.165 ± 0.056	0.369TyrTrp: 0.369 ± 0.025	1.517TyrTyr: 1.517 ± 0.059	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2269 proteins (680895 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---