Amino acid dipepetide frequency for Gordonia insulae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.622AlaAla: 18.622 ± 0.15
0.857AlaCys: 0.857 ± 0.024
9.431AlaAsp: 9.431 ± 0.095
7.483AlaGlu: 7.483 ± 0.087
3.485AlaPhe: 3.485 ± 0.049
11.853AlaGly: 11.853 ± 0.083
2.618AlaHis: 2.618 ± 0.039
5.788AlaIle: 5.788 ± 0.061
2.614AlaLys: 2.614 ± 0.055
11.998AlaLeu: 11.998 ± 0.088
2.815AlaMet: 2.815 ± 0.041
2.3AlaAsn: 2.3 ± 0.039
6.071AlaPro: 6.071 ± 0.067
3.648AlaGln: 3.648 ± 0.05
8.695AlaArg: 8.695 ± 0.086
6.004AlaSer: 6.004 ± 0.064
7.724AlaThr: 7.724 ± 0.065
11.492AlaVal: 11.492 ± 0.106
1.522AlaTrp: 1.522 ± 0.032
2.263AlaTyr: 2.263 ± 0.038
0.0AlaXaa: 0.0 ± 0.0
Cys
1.021CysAla: 1.021 ± 0.025
0.087CysCys: 0.087 ± 0.006
0.489CysAsp: 0.489 ± 0.017
0.349CysGlu: 0.349 ± 0.015
0.21CysPhe: 0.21 ± 0.012
0.836CysGly: 0.836 ± 0.024
0.172CysHis: 0.172 ± 0.011
0.278CysIle: 0.278 ± 0.013
0.096CysLys: 0.096 ± 0.007
0.587CysLeu: 0.587 ± 0.019
0.127CysMet: 0.127 ± 0.008
0.15CysAsn: 0.15 ± 0.009
0.406CysPro: 0.406 ± 0.015
0.168CysGln: 0.168 ± 0.009
0.544CysArg: 0.544 ± 0.022
0.463CysSer: 0.463 ± 0.014
0.462CysThr: 0.462 ± 0.017
0.623CysVal: 0.623 ± 0.019
0.111CysTrp: 0.111 ± 0.008
0.152CysTyr: 0.152 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
8.277AspAla: 8.277 ± 0.078
0.392AspCys: 0.392 ± 0.016
5.744AspAsp: 5.744 ± 0.063
4.493AspGlu: 4.493 ± 0.055
1.816AspPhe: 1.816 ± 0.036
6.467AspGly: 6.467 ± 0.063
1.817AspHis: 1.817 ± 0.032
2.729AspIle: 2.729 ± 0.042
1.255AspLys: 1.255 ± 0.033
6.977AspLeu: 6.977 ± 0.087
1.058AspMet: 1.058 ± 0.025
1.232AspAsn: 1.232 ± 0.031
4.695AspPro: 4.695 ± 0.064
1.807AspGln: 1.807 ± 0.037
5.304AspArg: 5.304 ± 0.07
3.111AspSer: 3.111 ± 0.045
3.518AspThr: 3.518 ± 0.045
6.063AspVal: 6.063 ± 0.083
0.979AspTrp: 0.979 ± 0.023
1.321AspTyr: 1.321 ± 0.026
0.0AspXaa: 0.0 ± 0.0
Glu
5.549GluAla: 5.549 ± 0.066
0.349GluCys: 0.349 ± 0.015
2.368GluAsp: 2.368 ± 0.044
2.322GluGlu: 2.322 ± 0.049
1.868GluPhe: 1.868 ± 0.031
3.21GluGly: 3.21 ± 0.051
1.439GluHis: 1.439 ± 0.03
2.971GluIle: 2.971 ± 0.042
1.276GluLys: 1.276 ± 0.034
6.267GluLeu: 6.267 ± 0.071
1.113GluMet: 1.113 ± 0.027
1.18GluAsn: 1.18 ± 0.029
2.901GluPro: 2.901 ± 0.045
2.018GluGln: 2.018 ± 0.046
4.453GluArg: 4.453 ± 0.055
3.171GluSer: 3.171 ± 0.044
2.732GluThr: 2.732 ± 0.039
4.46GluVal: 4.46 ± 0.051
0.827GluTrp: 0.827 ± 0.022
1.135GluTyr: 1.135 ± 0.024
0.0GluXaa: 0.0 ± 0.0
Phe
4.091PheAla: 4.091 ± 0.05
0.292PheCys: 0.292 ± 0.013
2.598PheAsp: 2.598 ± 0.047
1.447PheGlu: 1.447 ± 0.027
0.972PhePhe: 0.972 ± 0.027
3.491PheGly: 3.491 ± 0.047
0.646PheHis: 0.646 ± 0.022
1.117PheIle: 1.117 ± 0.026
0.407PheLys: 0.407 ± 0.017
2.513PheLeu: 2.513 ± 0.045
0.481PheMet: 0.481 ± 0.016
0.63PheAsn: 0.63 ± 0.02
1.367PhePro: 1.367 ± 0.028
0.602PheGln: 0.602 ± 0.019
1.767PheArg: 1.767 ± 0.032
1.627PheSer: 1.627 ± 0.033
2.08PheThr: 2.08 ± 0.032
2.74PheVal: 2.74 ± 0.037
0.437PheTrp: 0.437 ± 0.019
0.671PheTyr: 0.671 ± 0.021
0.0PheXaa: 0.0 ± 0.0
Gly
10.33GlyAla: 10.33 ± 0.083
0.73GlyCys: 0.73 ± 0.021
5.625GlyAsp: 5.625 ± 0.077
4.58GlyGlu: 4.58 ± 0.058
3.132GlyPhe: 3.132 ± 0.044
7.962GlyGly: 7.962 ± 0.094
2.07GlyHis: 2.07 ± 0.037
4.385GlyIle: 4.385 ± 0.058
2.211GlyLys: 2.211 ± 0.042
8.574GlyLeu: 8.574 ± 0.084
2.133GlyMet: 2.133 ± 0.038
1.882GlyAsn: 1.882 ± 0.034
4.569GlyPro: 4.569 ± 0.055
2.625GlyGln: 2.625 ± 0.039
6.737GlyArg: 6.737 ± 0.065
5.525GlySer: 5.525 ± 0.061
5.538GlyThr: 5.538 ± 0.059
7.863GlyVal: 7.863 ± 0.071
1.565GlyTrp: 1.565 ± 0.031
2.33GlyTyr: 2.33 ± 0.044
0.0GlyXaa: 0.0 ± 0.0
His
2.476HisAla: 2.476 ± 0.043
0.186HisCys: 0.186 ± 0.011
1.477HisAsp: 1.477 ± 0.025
1.106HisGlu: 1.106 ± 0.026
0.627HisPhe: 0.627 ± 0.019
2.06HisGly: 2.06 ± 0.035
0.751HisHis: 0.751 ± 0.025
0.87HisIle: 0.87 ± 0.021
0.346HisLys: 0.346 ± 0.014
2.202HisLeu: 2.202 ± 0.035
0.386HisMet: 0.386 ± 0.015
0.434HisAsn: 0.434 ± 0.015
1.633HisPro: 1.633 ± 0.032
0.612HisGln: 0.612 ± 0.016
2.005HisArg: 2.005 ± 0.033
1.059HisSer: 1.059 ± 0.023
1.231HisThr: 1.231 ± 0.028
1.707HisVal: 1.707 ± 0.03
0.328HisTrp: 0.328 ± 0.015
0.495HisTyr: 0.495 ± 0.017
0.0HisXaa: 0.0 ± 0.0
Ile
6.849IleAla: 6.849 ± 0.059
0.391IleCys: 0.391 ± 0.014
3.893IleAsp: 3.893 ± 0.043
2.603IleGlu: 2.603 ± 0.044
1.091IlePhe: 1.091 ± 0.031
4.999IleGly: 4.999 ± 0.061
0.837IleHis: 0.837 ± 0.021
1.776IleIle: 1.776 ± 0.041
0.808IleLys: 0.808 ± 0.021
3.424IleLeu: 3.424 ± 0.045
0.657IleMet: 0.657 ± 0.021
1.061IleAsn: 1.061 ± 0.022
2.539IlePro: 2.539 ± 0.04
0.861IleGln: 0.861 ± 0.023
3.009IleArg: 3.009 ± 0.042
2.588IleSer: 2.588 ± 0.037
3.084IleThr: 3.084 ± 0.044
4.275IleVal: 4.275 ± 0.054
0.525IleTrp: 0.525 ± 0.017
0.787IleTyr: 0.787 ± 0.022
0.0IleXaa: 0.0 ± 0.0
Lys
2.389LysAla: 2.389 ± 0.046
0.097LysCys: 0.097 ± 0.007
1.058LysAsp: 1.058 ± 0.027
0.914LysGlu: 0.914 ± 0.025
0.537LysPhe: 0.537 ± 0.019
1.493LysGly: 1.493 ± 0.036
0.419LysHis: 0.419 ± 0.016
1.008LysIle: 1.008 ± 0.026
0.682LysLys: 0.682 ± 0.033
1.835LysLeu: 1.835 ± 0.034
0.433LysMet: 0.433 ± 0.015
0.492LysAsn: 0.492 ± 0.017
1.209LysPro: 1.209 ± 0.034
0.669LysGln: 0.669 ± 0.023
1.405LysArg: 1.405 ± 0.028
1.23LysSer: 1.23 ± 0.032
1.246LysThr: 1.246 ± 0.026
1.883LysVal: 1.883 ± 0.043
0.265LysTrp: 0.265 ± 0.013
0.472LysTyr: 0.472 ± 0.017
0.0LysXaa: 0.0 ± 0.0
Leu
13.054LeuAla: 13.054 ± 0.09
0.789LeuCys: 0.789 ± 0.023
6.989LeuAsp: 6.989 ± 0.087
4.079LeuGlu: 4.079 ± 0.054
2.645LeuPhe: 2.645 ± 0.045
8.77LeuGly: 8.77 ± 0.082
1.912LeuHis: 1.912 ± 0.033
4.483LeuIle: 4.483 ± 0.064
1.527LeuLys: 1.527 ± 0.039
8.616LeuLeu: 8.616 ± 0.097
1.702LeuMet: 1.702 ± 0.038
1.801LeuAsn: 1.801 ± 0.036
5.45LeuPro: 5.45 ± 0.062
2.149LeuGln: 2.149 ± 0.036
7.237LeuArg: 7.237 ± 0.072
5.616LeuSer: 5.616 ± 0.055
6.437LeuThr: 6.437 ± 0.065
8.413LeuVal: 8.413 ± 0.076
1.105LeuTrp: 1.105 ± 0.025
1.592LeuTyr: 1.592 ± 0.031
0.0LeuXaa: 0.0 ± 0.0
Met
2.445MetAla: 2.445 ± 0.035
0.172MetCys: 0.172 ± 0.01
0.897MetAsp: 0.897 ± 0.023
0.668MetGlu: 0.668 ± 0.02
0.646MetPhe: 0.646 ± 0.019
1.481MetGly: 1.481 ± 0.032
0.397MetHis: 0.397 ± 0.017
1.055MetIle: 1.055 ± 0.027
0.427MetLys: 0.427 ± 0.015
1.965MetLeu: 1.965 ± 0.035
0.434MetMet: 0.434 ± 0.017
0.541MetAsn: 0.541 ± 0.017
1.165MetPro: 1.165 ± 0.029
0.559MetGln: 0.559 ± 0.019
1.503MetArg: 1.503 ± 0.026
1.801MetSer: 1.801 ± 0.033
1.987MetThr: 1.987 ± 0.033
1.728MetVal: 1.728 ± 0.036
0.275MetTrp: 0.275 ± 0.013
0.341MetTyr: 0.341 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
2.457AsnAla: 2.457 ± 0.044
0.156AsnCys: 0.156 ± 0.009
1.144AsnAsp: 1.144 ± 0.025
0.921AsnGlu: 0.921 ± 0.027
0.615AsnPhe: 0.615 ± 0.019
2.027AsnGly: 2.027 ± 0.036
0.404AsnHis: 0.404 ± 0.015
0.908AsnIle: 0.908 ± 0.022
0.442AsnLys: 0.442 ± 0.016
1.921AsnLeu: 1.921 ± 0.035
0.375AsnMet: 0.375 ± 0.015
0.516AsnAsn: 0.516 ± 0.018
1.657AsnPro: 1.657 ± 0.036
0.564AsnGln: 0.564 ± 0.019
1.546AsnArg: 1.546 ± 0.028
1.143AsnSer: 1.143 ± 0.025
1.271AsnThr: 1.271 ± 0.028
1.638AsnVal: 1.638 ± 0.033
0.348AsnTrp: 0.348 ± 0.013
0.487AsnTyr: 0.487 ± 0.017
0.0AsnXaa: 0.0 ± 0.0
Pro
7.001ProAla: 7.001 ± 0.071
0.264ProCys: 0.264 ± 0.014
4.802ProAsp: 4.802 ± 0.052
3.579ProGlu: 3.579 ± 0.043
1.597ProPhe: 1.597 ± 0.03
5.457ProGly: 5.457 ± 0.055
1.174ProHis: 1.174 ± 0.025
2.388ProIle: 2.388 ± 0.037
1.159ProLys: 1.159 ± 0.028
4.535ProLeu: 4.535 ± 0.05
1.2ProMet: 1.2 ± 0.027
1.198ProAsn: 1.198 ± 0.028
2.912ProPro: 2.912 ± 0.051
1.51ProGln: 1.51 ± 0.027
3.469ProArg: 3.469 ± 0.045
3.196ProSer: 3.196 ± 0.043
3.914ProThr: 3.914 ± 0.047
5.014ProVal: 5.014 ± 0.061
0.757ProTrp: 0.757 ± 0.024
1.057ProTyr: 1.057 ± 0.026
0.0ProXaa: 0.0 ± 0.0
Gln
3.104GlnAla: 3.104 ± 0.044
0.185GlnCys: 0.185 ± 0.011
1.073GlnAsp: 1.073 ± 0.023
1.058GlnGlu: 1.058 ± 0.025
0.873GlnPhe: 0.873 ± 0.024
1.886GlnGly: 1.886 ± 0.041
0.602GlnHis: 0.602 ± 0.019
1.563GlnIle: 1.563 ± 0.027
0.621GlnLys: 0.621 ± 0.021
2.93GlnLeu: 2.93 ± 0.047
0.674GlnMet: 0.674 ± 0.021
0.614GlnAsn: 0.614 ± 0.018
1.484GlnPro: 1.484 ± 0.033
1.135GlnGln: 1.135 ± 0.032
2.427GlnArg: 2.427 ± 0.04
1.488GlnSer: 1.488 ± 0.03
1.55GlnThr: 1.55 ± 0.03
2.448GlnVal: 2.448 ± 0.036
0.456GlnTrp: 0.456 ± 0.017
0.605GlnTyr: 0.605 ± 0.022
0.0GlnXaa: 0.0 ± 0.0
Arg
8.343ArgAla: 8.343 ± 0.075
0.516ArgCys: 0.516 ± 0.018
4.641ArgAsp: 4.641 ± 0.055
3.811ArgGlu: 3.811 ± 0.053
2.364ArgPhe: 2.364 ± 0.031
5.359ArgGly: 5.359 ± 0.054
1.853ArgHis: 1.853 ± 0.036
3.575ArgIle: 3.575 ± 0.047
1.522ArgLys: 1.522 ± 0.035
7.154ArgLeu: 7.154 ± 0.088
1.851ArgMet: 1.851 ± 0.029
1.55ArgAsn: 1.55 ± 0.032
4.196ArgPro: 4.196 ± 0.07
2.061ArgGln: 2.061 ± 0.038
6.728ArgArg: 6.728 ± 0.082
4.545ArgSer: 4.545 ± 0.053
4.632ArgThr: 4.632 ± 0.058
5.784ArgVal: 5.784 ± 0.061
1.318ArgTrp: 1.318 ± 0.032
1.753ArgTyr: 1.753 ± 0.031
0.0ArgXaa: 0.0 ± 0.0
Ser
7.442SerAla: 7.442 ± 0.07
0.388SerCys: 0.388 ± 0.019
3.624SerAsp: 3.624 ± 0.039
2.638SerGlu: 2.638 ± 0.048
1.733SerPhe: 1.733 ± 0.031
6.134SerGly: 6.134 ± 0.067
1.016SerHis: 1.016 ± 0.024
2.484SerIle: 2.484 ± 0.038
1.045SerLys: 1.045 ± 0.026
4.869SerLeu: 4.869 ± 0.059
1.452SerMet: 1.452 ± 0.025
1.043SerAsn: 1.043 ± 0.023
3.24SerPro: 3.24 ± 0.045
1.337SerGln: 1.337 ± 0.028
3.86SerArg: 3.86 ± 0.049
3.65SerSer: 3.65 ± 0.056
3.94SerThr: 3.94 ± 0.045
5.057SerVal: 5.057 ± 0.068
0.887SerTrp: 0.887 ± 0.026
1.156SerTyr: 1.156 ± 0.026
0.0SerXaa: 0.0 ± 0.0
Thr
8.048ThrAla: 8.048 ± 0.068
0.435ThrCys: 0.435 ± 0.017
4.524ThrAsp: 4.524 ± 0.059
3.4ThrGlu: 3.4 ± 0.051
1.887ThrPhe: 1.887 ± 0.035
6.124ThrGly: 6.124 ± 0.06
1.244ThrHis: 1.244 ± 0.025
2.908ThrIle: 2.908 ± 0.044
1.175ThrLys: 1.175 ± 0.03
5.584ThrLeu: 5.584 ± 0.058
1.325ThrMet: 1.325 ± 0.027
1.176ThrAsn: 1.176 ± 0.025
4.109ThrPro: 4.109 ± 0.051
1.415ThrGln: 1.415 ± 0.031
4.011ThrArg: 4.011 ± 0.049
3.808ThrSer: 3.808 ± 0.048
4.588ThrThr: 4.588 ± 0.063
6.11ThrVal: 6.11 ± 0.066
0.876ThrTrp: 0.876 ± 0.023
1.299ThrTyr: 1.299 ± 0.028
0.0ThrXaa: 0.0 ± 0.0
Val
12.011ValAla: 12.011 ± 0.103
0.719ValCys: 0.719 ± 0.021
6.593ValAsp: 6.593 ± 0.068
4.617ValGlu: 4.617 ± 0.05
2.587ValPhe: 2.587 ± 0.048
7.759ValGly: 7.759 ± 0.08
1.857ValHis: 1.857 ± 0.038
4.417ValIle: 4.417 ± 0.053
1.46ValLys: 1.46 ± 0.033
8.587ValLeu: 8.587 ± 0.083
1.611ValMet: 1.611 ± 0.029
1.925ValAsn: 1.925 ± 0.037
4.711ValPro: 4.711 ± 0.066
1.856ValGln: 1.856 ± 0.036
5.865ValArg: 5.865 ± 0.066
4.916ValSer: 4.916 ± 0.05
5.995ValThr: 5.995 ± 0.061
9.143ValVal: 9.143 ± 0.084
1.039ValTrp: 1.039 ± 0.027
1.471ValTyr: 1.471 ± 0.029
0.0ValXaa: 0.0 ± 0.0
Trp
1.483TrpAla: 1.483 ± 0.028
0.144TrpCys: 0.144 ± 0.009
0.779TrpAsp: 0.779 ± 0.025
0.595TrpGlu: 0.595 ± 0.019
0.555TrpPhe: 0.555 ± 0.017
1.025TrpGly: 1.025 ± 0.021
0.336TrpHis: 0.336 ± 0.015
0.685TrpIle: 0.685 ± 0.022
0.323TrpLys: 0.323 ± 0.014
1.583TrpLeu: 1.583 ± 0.029
0.354TrpMet: 0.354 ± 0.014
0.378TrpAsn: 0.378 ± 0.014
0.714TrpPro: 0.714 ± 0.017
0.566TrpGln: 0.566 ± 0.018
1.185TrpArg: 1.185 ± 0.029
0.946TrpSer: 0.946 ± 0.025
0.927TrpThr: 0.927 ± 0.023
1.089TrpVal: 1.089 ± 0.029
0.351TrpTrp: 0.351 ± 0.017
0.326TrpTyr: 0.326 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.292TyrAla: 2.292 ± 0.034
0.182TyrCys: 0.182 ± 0.011
1.307TyrAsp: 1.307 ± 0.032
0.948TyrGlu: 0.948 ± 0.028
0.738TyrPhe: 0.738 ± 0.02
1.973TyrGly: 1.973 ± 0.04
0.426TyrHis: 0.426 ± 0.019
0.672TyrIle: 0.672 ± 0.02
0.341TyrLys: 0.341 ± 0.014
2.244TyrLeu: 2.244 ± 0.04
0.303TyrMet: 0.303 ± 0.015
0.438TyrAsn: 0.438 ± 0.014
1.153TyrPro: 1.153 ± 0.026
0.613TyrGln: 0.613 ± 0.02
1.807TyrArg: 1.807 ± 0.03
1.112TyrSer: 1.112 ± 0.032
1.189TyrThr: 1.189 ± 0.028
1.606TyrVal: 1.606 ± 0.032
0.372TyrTrp: 0.372 ± 0.013
0.45TyrTyr: 0.45 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5417 proteins (1825819 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski