Human respiratory syncytial virus B (strain B1)

Taxonomy: Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina; Monjiviricetes; Mononegavirales; Pneumoviridae; Orthopneumovirus; Human orthopneumovirus; Human respiratory syncytial virus B

Average proteome isoelectric point is 7.26

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 12 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|O42083|NS1_HRSVB Non-structural protein 1 OS=Human respiratory syncytial virus B (strain B1) OX=79692 GN=1C PE=3 SV=1
MM1 pKa = 7.59EE2 pKa = 4.71KK3 pKa = 10.15FAPEE7 pKa = 3.71FHH9 pKa = 7.46GEE11 pKa = 3.97DD12 pKa = 3.96ANNKK16 pKa = 6.8ATKK19 pKa = 9.89FLEE22 pKa = 4.49SIKK25 pKa = 11.04GKK27 pKa = 9.68FASSKK32 pKa = 10.59DD33 pKa = 3.64PKK35 pKa = 10.63KK36 pKa = 10.0KK37 pKa = 10.5DD38 pKa = 3.34SIISVNSIDD47 pKa = 4.07IEE49 pKa = 4.43VTKK52 pKa = 10.35EE53 pKa = 3.85SPITSGTNIINPTSEE68 pKa = 4.3ADD70 pKa = 3.49STPEE74 pKa = 3.56TKK76 pKa = 10.56ANYY79 pKa = 7.9PRR81 pKa = 11.84KK82 pKa = 9.07PLVSFKK88 pKa = 11.1EE89 pKa = 4.01DD90 pKa = 3.61LTPSDD95 pKa = 3.85NPFSKK100 pKa = 10.44LYY102 pKa = 10.59KK103 pKa = 9.24EE104 pKa = 4.59TIEE107 pKa = 4.06TFDD110 pKa = 3.63NNEE113 pKa = 3.96EE114 pKa = 4.04EE115 pKa = 4.21SSYY118 pKa = 11.27SYY120 pKa = 11.54EE121 pKa = 4.37EE122 pKa = 5.29INDD125 pKa = 3.58QTNDD129 pKa = 3.44NITARR134 pKa = 11.84LDD136 pKa = 4.15RR137 pKa = 11.84IDD139 pKa = 4.16EE140 pKa = 4.3KK141 pKa = 11.17LSEE144 pKa = 4.26ILGMLHH150 pKa = 5.8TLVVASAGPTSARR163 pKa = 11.84DD164 pKa = 4.03GIRR167 pKa = 11.84DD168 pKa = 3.39AMVGLRR174 pKa = 11.84EE175 pKa = 3.96EE176 pKa = 4.45MIEE179 pKa = 4.21KK180 pKa = 9.97IRR182 pKa = 11.84AEE184 pKa = 3.8ALMTNDD190 pKa = 3.82RR191 pKa = 11.84LEE193 pKa = 4.27AMARR197 pKa = 11.84LRR199 pKa = 11.84NEE201 pKa = 4.35EE202 pKa = 4.19SEE204 pKa = 4.95KK205 pKa = 9.88MAKK208 pKa = 8.76DD209 pKa = 3.31TSDD212 pKa = 3.83EE213 pKa = 4.31VPLNPTSKK221 pKa = 10.69KK222 pKa = 10.68LSDD225 pKa = 3.9LLEE228 pKa = 5.54DD229 pKa = 4.0NDD231 pKa = 4.54SDD233 pKa = 5.0NDD235 pKa = 3.91LSLDD239 pKa = 3.79DD240 pKa = 4.38FF241 pKa = 5.17

Molecular weight: 26.99 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|O36634|FUS_HRSVB Fusion glycoprotein F0 OS=Human respiratory syncytial virus B (strain B1) OX=79692 GN=F PE=1 SV=1
MM1 pKa = 7.61SKK3 pKa = 10.42HH4 pKa = 5.73KK5 pKa = 10.15NQRR8 pKa = 11.84TARR11 pKa = 11.84TLEE14 pKa = 4.25KK15 pKa = 9.96TWDD18 pKa = 3.85TLNHH22 pKa = 6.82LIVISSCLYY31 pKa = 10.14RR32 pKa = 11.84LNLKK36 pKa = 10.43SIAQIALSVLAMIISTSLIIAAIIFIISANHH67 pKa = 6.21KK68 pKa = 8.75VTLTTVTVQTIKK80 pKa = 10.85NHH82 pKa = 4.47TEE84 pKa = 3.91KK85 pKa = 11.17NITTYY90 pKa = 9.32LTQVPPEE97 pKa = 4.09RR98 pKa = 11.84VSSSKK103 pKa = 10.67QPTTTSPIHH112 pKa = 5.99TNSATTSPNTKK123 pKa = 10.0SEE125 pKa = 4.22THH127 pKa = 5.91HH128 pKa = 5.9TTAQTKK134 pKa = 10.05GRR136 pKa = 11.84TTTSTQTNKK145 pKa = 10.25PSTKK149 pKa = 9.48PRR151 pKa = 11.84LKK153 pKa = 10.72NPPKK157 pKa = 10.29KK158 pKa = 10.31PKK160 pKa = 9.94DD161 pKa = 3.65DD162 pKa = 3.53YY163 pKa = 11.35HH164 pKa = 8.1FEE166 pKa = 4.02VFNFVPCSICGNNQLCKK183 pKa = 10.21SICKK187 pKa = 8.93TIPSNKK193 pKa = 8.61PKK195 pKa = 10.34KK196 pKa = 10.27KK197 pKa = 8.93PTIKK201 pKa = 9.27PTNKK205 pKa = 8.47PTTKK209 pKa = 8.25TTNKK213 pKa = 9.62RR214 pKa = 11.84DD215 pKa = 3.54PKK217 pKa = 10.43TPAKK221 pKa = 6.29TTKK224 pKa = 10.47KK225 pKa = 9.01EE226 pKa = 4.13TTTNPTKK233 pKa = 10.7KK234 pKa = 8.82PTLTTTEE241 pKa = 4.53RR242 pKa = 11.84DD243 pKa = 3.41TSTSQSTVLDD253 pKa = 3.89TTTLEE258 pKa = 4.25HH259 pKa = 7.08TIQQQSLHH267 pKa = 5.77STTPEE272 pKa = 3.55NTPNSTQTPTASEE285 pKa = 4.36PSTSNSTQNTQSHH298 pKa = 5.97AA299 pKa = 3.75

Molecular weight: 32.97 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

11

1

12

4792

65

2166

399.3

45.3

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.111 ± 0.59

1.732 ± 0.204

4.633 ± 0.523

5.071 ± 0.561

3.443 ± 0.487

3.652 ± 0.577

2.504 ± 0.339

9.015 ± 0.478

8.076 ± 0.445

10.538 ± 1.176

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.295 ± 0.286

7.846 ± 0.334

3.902 ± 0.763

3.13 ± 0.353

3.339 ± 0.275

8.598 ± 0.427

8.598 ± 2.268

4.883 ± 0.456

0.772 ± 0.227

3.861 ± 0.632
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski