Amino acid dipepetide frequency for Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.169AlaAla: 8.169 ± 0.058	1.152AlaCys: 1.152 ± 0.014	4.086AlaAsp: 4.086 ± 0.023	4.944AlaGlu: 4.944 ± 0.031	3.16AlaPhe: 3.16 ± 0.022	5.37AlaGly: 5.37 ± 0.03	1.697AlaHis: 1.697 ± 0.015	4.524AlaIle: 4.524 ± 0.025	4.119AlaLys: 4.119 ± 0.031	7.53AlaLeu: 7.53 ± 0.034	1.982AlaMet: 1.982 ± 0.015	2.957AlaAsn: 2.957 ± 0.019	4.442AlaPro: 4.442 ± 0.033	3.262AlaGln: 3.262 ± 0.024	4.532AlaArg: 4.532 ± 0.026	6.957AlaSer: 6.957 ± 0.038	5.183AlaThr: 5.183 ± 0.028	5.15AlaVal: 5.15 ± 0.03	1.217AlaTrp: 1.217 ± 0.013	2.164AlaTyr: 2.164 ± 0.018	0.0AlaXaa: 0.0 ± 0.0
Cys	0.946CysAla: 0.946 ± 0.011	0.263CysCys: 0.263 ± 0.007	0.752CysAsp: 0.752 ± 0.009	0.677CysGlu: 0.677 ± 0.01	0.602CysPhe: 0.602 ± 0.01	0.979CysGly: 0.979 ± 0.013	0.383CysHis: 0.383 ± 0.007	0.804CysIle: 0.804 ± 0.011	0.608CysLys: 0.608 ± 0.011	1.367CysLeu: 1.367 ± 0.016	0.297CysMet: 0.297 ± 0.007	0.506CysAsn: 0.506 ± 0.008	0.694CysPro: 0.694 ± 0.01	0.539CysGln: 0.539 ± 0.009	0.81CysArg: 0.81 ± 0.011	0.999CysSer: 0.999 ± 0.012	0.746CysThr: 0.746 ± 0.011	0.83CysVal: 0.83 ± 0.011	0.235CysTrp: 0.235 ± 0.006	0.413CysTyr: 0.413 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.573AspAla: 4.573 ± 0.022	0.7AspCys: 0.7 ± 0.011	4.326AspAsp: 4.326 ± 0.032	4.542AspGlu: 4.542 ± 0.032	2.288AspPhe: 2.288 ± 0.018	4.03AspGly: 4.03 ± 0.029	1.335AspHis: 1.335 ± 0.013	3.305AspIle: 3.305 ± 0.021	2.738AspLys: 2.738 ± 0.021	5.144AspLeu: 5.144 ± 0.026	1.343AspMet: 1.343 ± 0.012	2.09AspAsn: 2.09 ± 0.015	3.28AspPro: 3.28 ± 0.025	2.001AspGln: 2.001 ± 0.016	2.965AspArg: 2.965 ± 0.023	4.148AspSer: 4.148 ± 0.024	3.066AspThr: 3.066 ± 0.021	3.653AspVal: 3.653 ± 0.023	0.979AspTrp: 0.979 ± 0.011	1.659AspTyr: 1.659 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.498GluAla: 5.498 ± 0.03	0.689GluCys: 0.689 ± 0.009	4.148GluAsp: 4.148 ± 0.031	5.197GluGlu: 5.197 ± 0.045	2.015GluPhe: 2.015 ± 0.017	3.597GluGly: 3.597 ± 0.021	1.453GluHis: 1.453 ± 0.013	3.12GluIle: 3.12 ± 0.02	3.683GluLys: 3.683 ± 0.026	5.218GluLeu: 5.218 ± 0.027	1.45GluMet: 1.45 ± 0.013	2.371GluAsn: 2.371 ± 0.019	2.938GluPro: 2.938 ± 0.03	2.429GluGln: 2.429 ± 0.019	3.722GluArg: 3.722 ± 0.026	4.331GluSer: 4.331 ± 0.03	3.797GluThr: 3.797 ± 0.026	3.593GluVal: 3.593 ± 0.023	0.948GluTrp: 0.948 ± 0.012	1.703GluTyr: 1.703 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	2.985PheAla: 2.985 ± 0.021	0.619PheCys: 0.619 ± 0.01	2.369PheAsp: 2.369 ± 0.019	2.221PheGlu: 2.221 ± 0.019	1.678PhePhe: 1.678 ± 0.019	2.852PheGly: 2.852 ± 0.021	0.928PheHis: 0.928 ± 0.011	2.003PheIle: 2.003 ± 0.017	1.677PheLys: 1.677 ± 0.013	3.535PheLeu: 3.535 ± 0.023	0.843PheMet: 0.843 ± 0.01	1.559PheAsn: 1.559 ± 0.013	1.944PhePro: 1.944 ± 0.016	1.468PheGln: 1.468 ± 0.014	1.974PheArg: 1.974 ± 0.016	3.013PheSer: 3.013 ± 0.02	2.238PheThr: 2.238 ± 0.017	2.362PheVal: 2.362 ± 0.019	0.677PheTrp: 0.677 ± 0.011	1.141PheTyr: 1.141 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	4.963GlyAla: 4.963 ± 0.03	0.955GlyCys: 0.955 ± 0.013	3.677GlyAsp: 3.677 ± 0.029	3.426GlyGlu: 3.426 ± 0.022	2.857GlyPhe: 2.857 ± 0.022	5.141GlyGly: 5.141 ± 0.041	1.717GlyHis: 1.717 ± 0.015	3.659GlyIle: 3.659 ± 0.026	3.397GlyLys: 3.397 ± 0.022	6.059GlyLeu: 6.059 ± 0.031	1.542GlyMet: 1.542 ± 0.015	2.638GlyAsn: 2.638 ± 0.023	3.227GlyPro: 3.227 ± 0.025	2.568GlyGln: 2.568 ± 0.019	3.87GlyArg: 3.87 ± 0.025	5.584GlySer: 5.584 ± 0.035	3.941GlyThr: 3.941 ± 0.034	4.103GlyVal: 4.103 ± 0.029	1.2GlyTrp: 1.2 ± 0.013	2.171GlyTyr: 2.171 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.761HisAla: 1.761 ± 0.013	0.36HisCys: 0.36 ± 0.006	1.419HisAsp: 1.419 ± 0.015	1.411HisGlu: 1.411 ± 0.014	0.972HisPhe: 0.972 ± 0.011	1.772HisGly: 1.772 ± 0.017	0.872HisHis: 0.872 ± 0.015	1.323HisIle: 1.323 ± 0.012	1.024HisLys: 1.024 ± 0.012	2.305HisLeu: 2.305 ± 0.017	0.528HisMet: 0.528 ± 0.008	0.897HisAsn: 0.897 ± 0.01	1.553HisPro: 1.553 ± 0.016	1.053HisGln: 1.053 ± 0.013	1.523HisArg: 1.523 ± 0.015	1.797HisSer: 1.797 ± 0.016	1.227HisThr: 1.227 ± 0.012	1.456HisVal: 1.456 ± 0.014	0.387HisTrp: 0.387 ± 0.006	0.728HisTyr: 0.728 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.306IleAla: 4.306 ± 0.026	0.834IleCys: 0.834 ± 0.012	3.07IleAsp: 3.07 ± 0.02	3.107IleGlu: 3.107 ± 0.021	2.085IlePhe: 2.085 ± 0.018	3.319IleGly: 3.319 ± 0.027	1.301IleHis: 1.301 ± 0.014	2.806IleIle: 2.806 ± 0.024	2.414IleLys: 2.414 ± 0.02	4.765IleLeu: 4.765 ± 0.03	1.121IleMet: 1.121 ± 0.011	2.002IleAsn: 2.002 ± 0.017	3.104IlePro: 3.104 ± 0.02	2.06IleGln: 2.06 ± 0.018	2.913IleArg: 2.913 ± 0.021	4.04IleSer: 4.04 ± 0.021	3.067IleThr: 3.067 ± 0.029	3.247IleVal: 3.247 ± 0.022	0.823IleTrp: 0.823 ± 0.01	1.498IleTyr: 1.498 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.406LysAla: 4.406 ± 0.027	0.591LysCys: 0.591 ± 0.01	3.097LysAsp: 3.097 ± 0.021	3.402LysGlu: 3.402 ± 0.028	1.559LysPhe: 1.559 ± 0.014	3.07LysGly: 3.07 ± 0.02	1.229LysHis: 1.229 ± 0.013	2.367LysIle: 2.367 ± 0.018	3.36LysLys: 3.36 ± 0.033	4.277LysLeu: 4.277 ± 0.03	1.036LysMet: 1.036 ± 0.013	1.89LysAsn: 1.89 ± 0.018	2.908LysPro: 2.908 ± 0.023	1.889LysGln: 1.889 ± 0.016	3.374LysArg: 3.374 ± 0.027	3.589LysSer: 3.589 ± 0.024	3.1LysThr: 3.1 ± 0.019	2.905LysVal: 2.905 ± 0.018	0.76LysTrp: 0.76 ± 0.009	1.439LysTyr: 1.439 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.627LeuAla: 7.627 ± 0.036	1.3LeuCys: 1.3 ± 0.013	5.249LeuAsp: 5.249 ± 0.024	5.582LeuGlu: 5.582 ± 0.03	3.392LeuPhe: 3.392 ± 0.025	5.863LeuGly: 5.863 ± 0.034	2.22LeuHis: 2.22 ± 0.017	4.224LeuIle: 4.224 ± 0.025	4.384LeuLys: 4.384 ± 0.029	8.196LeuLeu: 8.196 ± 0.047	1.851LeuMet: 1.851 ± 0.017	3.24LeuAsn: 3.24 ± 0.022	5.303LeuPro: 5.303 ± 0.029	3.852LeuGln: 3.852 ± 0.023	5.563LeuArg: 5.563 ± 0.033	7.229LeuSer: 7.229 ± 0.034	4.856LeuThr: 4.856 ± 0.024	5.416LeuVal: 5.416 ± 0.032	1.28LeuTrp: 1.28 ± 0.012	2.372LeuTyr: 2.372 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	2.274MetAla: 2.274 ± 0.019	0.265MetCys: 0.265 ± 0.006	1.252MetAsp: 1.252 ± 0.014	1.283MetGlu: 1.283 ± 0.013	0.788MetPhe: 0.788 ± 0.01	1.46MetGly: 1.46 ± 0.012	0.499MetHis: 0.499 ± 0.008	1.095MetIle: 1.095 ± 0.012	1.078MetLys: 1.078 ± 0.012	1.833MetLeu: 1.833 ± 0.016	0.616MetMet: 0.616 ± 0.01	0.848MetAsn: 0.848 ± 0.011	1.318MetPro: 1.318 ± 0.014	0.839MetGln: 0.839 ± 0.011	1.229MetArg: 1.229 ± 0.013	1.992MetSer: 1.992 ± 0.015	1.376MetThr: 1.376 ± 0.012	1.327MetVal: 1.327 ± 0.012	0.276MetTrp: 0.276 ± 0.005	0.54MetTyr: 0.54 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.07AsnAla: 3.07 ± 0.025	0.518AsnCys: 0.518 ± 0.009	2.135AsnAsp: 2.135 ± 0.016	2.161AsnGlu: 2.161 ± 0.017	1.43AsnPhe: 1.43 ± 0.015	3.013AsnGly: 3.013 ± 0.024	0.914AsnHis: 0.914 ± 0.011	2.176AsnIle: 2.176 ± 0.018	1.796AsnLys: 1.796 ± 0.014	3.37AsnLeu: 3.37 ± 0.022	0.936AsnMet: 0.936 ± 0.011	1.652AsnAsn: 1.652 ± 0.018	2.429AsnPro: 2.429 ± 0.02	1.424AsnGln: 1.424 ± 0.014	2.005AsnArg: 2.005 ± 0.017	2.868AsnSer: 2.868 ± 0.018	2.281AsnThr: 2.281 ± 0.02	2.297AsnVal: 2.297 ± 0.019	0.638AsnTrp: 0.638 ± 0.008	1.096AsnTyr: 1.096 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	4.726ProAla: 4.726 ± 0.038	0.574ProCys: 0.574 ± 0.009	3.263ProAsp: 3.263 ± 0.024	3.963ProGlu: 3.963 ± 0.025	2.082ProPhe: 2.082 ± 0.017	3.901ProGly: 3.901 ± 0.037	1.288ProHis: 1.288 ± 0.012	2.589ProIle: 2.589 ± 0.02	2.793ProLys: 2.793 ± 0.02	4.559ProLeu: 4.559 ± 0.027	1.111ProMet: 1.111 ± 0.012	2.223ProAsn: 2.223 ± 0.017	4.46ProPro: 4.46 ± 0.05	2.441ProGln: 2.441 ± 0.024	3.246ProArg: 3.246 ± 0.026	5.568ProSer: 5.568 ± 0.032	3.815ProThr: 3.815 ± 0.027	3.504ProVal: 3.504 ± 0.028	0.797ProTrp: 0.797 ± 0.01	1.514ProTyr: 1.514 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	3.472GlnAla: 3.472 ± 0.024	0.484GlnCys: 0.484 ± 0.008	2.293GlnAsp: 2.293 ± 0.019	2.497GlnGlu: 2.497 ± 0.021	1.318GlnPhe: 1.318 ± 0.013	2.49GlnGly: 2.49 ± 0.019	1.089GlnHis: 1.089 ± 0.012	1.904GlnIle: 1.904 ± 0.017	2.006GlnLys: 2.006 ± 0.018	3.5GlnLeu: 3.5 ± 0.021	0.889GlnMet: 0.889 ± 0.012	1.599GlnAsn: 1.599 ± 0.014	2.568GlnPro: 2.568 ± 0.026	2.369GlnGln: 2.369 ± 0.036	2.583GlnArg: 2.583 ± 0.021	3.072GlnSer: 3.072 ± 0.024	2.335GlnThr: 2.335 ± 0.019	2.259GlnVal: 2.259 ± 0.015	0.61GlnTrp: 0.61 ± 0.009	1.172GlnTyr: 1.172 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	4.283ArgAla: 4.283 ± 0.027	0.768ArgCys: 0.768 ± 0.011	3.396ArgAsp: 3.396 ± 0.027	3.619ArgGlu: 3.619 ± 0.028	2.161ArgPhe: 2.161 ± 0.017	3.497ArgGly: 3.497 ± 0.027	1.584ArgHis: 1.584 ± 0.013	2.91ArgIle: 2.91 ± 0.022	3.314ArgLys: 3.314 ± 0.023	5.439ArgLeu: 5.439 ± 0.031	1.276ArgMet: 1.276 ± 0.013	2.287ArgAsn: 2.287 ± 0.018	3.349ArgPro: 3.349 ± 0.023	2.616ArgGln: 2.616 ± 0.019	4.781ArgArg: 4.781 ± 0.039	4.516ArgSer: 4.516 ± 0.031	3.131ArgThr: 3.131 ± 0.021	3.261ArgVal: 3.261 ± 0.017	0.977ArgTrp: 0.977 ± 0.013	1.718ArgTyr: 1.718 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.11SerAla: 6.11 ± 0.027	0.996SerCys: 0.996 ± 0.013	4.376SerAsp: 4.376 ± 0.028	4.212SerGlu: 4.212 ± 0.024	3.099SerPhe: 3.099 ± 0.022	5.35SerGly: 5.35 ± 0.037	1.999SerHis: 1.999 ± 0.018	4.213SerIle: 4.213 ± 0.024	3.828SerLys: 3.828 ± 0.023	7.126SerLeu: 7.126 ± 0.032	1.765SerMet: 1.765 ± 0.015	3.053SerAsn: 3.053 ± 0.02	5.144SerPro: 5.144 ± 0.036	3.35SerGln: 3.35 ± 0.022	4.803SerArg: 4.803 ± 0.031	8.179SerSer: 8.179 ± 0.057	5.35SerThr: 5.35 ± 0.037	4.489SerVal: 4.489 ± 0.027	1.25SerTrp: 1.25 ± 0.014	2.151SerTyr: 2.151 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.065ThrAla: 5.065 ± 0.029	0.848ThrCys: 0.848 ± 0.012	2.947ThrAsp: 2.947 ± 0.021	3.345ThrGlu: 3.345 ± 0.026	2.273ThrPhe: 2.273 ± 0.018	4.103ThrGly: 4.103 ± 0.032	1.277ThrHis: 1.277 ± 0.013	3.34ThrIle: 3.34 ± 0.037	2.881ThrLys: 2.881 ± 0.02	5.161ThrLeu: 5.161 ± 0.029	1.234ThrMet: 1.234 ± 0.011	2.228ThrAsn: 2.228 ± 0.016	4.116ThrPro: 4.116 ± 0.03	2.193ThrGln: 2.193 ± 0.019	3.153ThrArg: 3.153 ± 0.021	5.232ThrSer: 5.232 ± 0.035	4.365ThrThr: 4.365 ± 0.055	3.77ThrVal: 3.77 ± 0.038	0.937ThrTrp: 0.937 ± 0.012	1.687ThrTyr: 1.687 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.055ValAla: 5.055 ± 0.03	0.848ValCys: 0.848 ± 0.011	3.689ValAsp: 3.689 ± 0.021	3.809ValGlu: 3.809 ± 0.027	2.516ValPhe: 2.516 ± 0.018	3.784ValGly: 3.784 ± 0.023	1.382ValHis: 1.382 ± 0.013	3.173ValIle: 3.173 ± 0.024	3.014ValLys: 3.014 ± 0.023	5.451ValLeu: 5.451 ± 0.029	1.341ValMet: 1.341 ± 0.013	2.273ValAsn: 2.273 ± 0.018	3.469ValPro: 3.469 ± 0.024	2.384ValGln: 2.384 ± 0.018	3.186ValArg: 3.186 ± 0.019	4.544ValSer: 4.544 ± 0.027	3.649ValThr: 3.649 ± 0.037	4.141ValVal: 4.141 ± 0.028	0.884ValTrp: 0.884 ± 0.011	1.766ValTyr: 1.766 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	1.193TrpAla: 1.193 ± 0.014	0.22TrpCys: 0.22 ± 0.005	0.922TrpAsp: 0.922 ± 0.012	0.901TrpGlu: 0.901 ± 0.011	0.607TrpPhe: 0.607 ± 0.009	0.985TrpGly: 0.985 ± 0.013	0.393TrpHis: 0.393 ± 0.007	0.882TrpIle: 0.882 ± 0.01	0.899TrpLys: 0.899 ± 0.011	1.482TrpLeu: 1.482 ± 0.015	0.384TrpMet: 0.384 ± 0.007	0.694TrpAsn: 0.694 ± 0.01	0.685TrpPro: 0.685 ± 0.009	0.609TrpGln: 0.609 ± 0.009	0.968TrpArg: 0.968 ± 0.011	1.131TrpSer: 1.131 ± 0.009	0.994TrpThr: 0.994 ± 0.011	0.958TrpVal: 0.958 ± 0.011	0.301TrpTrp: 0.301 ± 0.007	0.476TrpTyr: 0.476 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.117TyrAla: 2.117 ± 0.017	0.464TyrCys: 0.464 ± 0.007	1.698TyrAsp: 1.698 ± 0.014	1.597TyrGlu: 1.597 ± 0.017	1.205TyrPhe: 1.205 ± 0.011	2.119TyrGly: 2.119 ± 0.018	0.808TyrHis: 0.808 ± 0.009	1.465TyrIle: 1.465 ± 0.014	1.236TyrLys: 1.236 ± 0.015	2.683TyrLeu: 2.683 ± 0.02	0.646TyrMet: 0.646 ± 0.008	1.198TyrAsn: 1.198 ± 0.013	1.489TyrPro: 1.489 ± 0.015	1.163TyrGln: 1.163 ± 0.015	1.681TyrArg: 1.681 ± 0.015	2.055TyrSer: 2.055 ± 0.019	1.639TyrThr: 1.639 ± 0.016	1.637TyrVal: 1.637 ± 0.015	0.508TyrTrp: 0.508 ± 0.008	0.945TyrTyr: 0.945 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 17784 proteins (8238472 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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