Amino acid dipepetide frequency for Hubei picorna-like virus 37

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.148AlaAla: 6.148 ± 0.0
1.366AlaCys: 1.366 ± 0.0
3.415AlaAsp: 3.415 ± 0.0
2.049AlaGlu: 2.049 ± 0.0
1.708AlaPhe: 1.708 ± 0.0
5.464AlaGly: 5.464 ± 0.0
1.708AlaHis: 1.708 ± 0.0
2.391AlaIle: 2.391 ± 0.0
5.464AlaLys: 5.464 ± 0.0
7.172AlaLeu: 7.172 ± 0.0
0.683AlaMet: 0.683 ± 0.0
2.732AlaAsn: 2.732 ± 0.0
3.074AlaPro: 3.074 ± 0.0
2.391AlaGln: 2.391 ± 0.0
4.098AlaArg: 4.098 ± 0.0
4.44AlaSer: 4.44 ± 0.0
6.148AlaThr: 6.148 ± 0.0
2.732AlaVal: 2.732 ± 0.0
0.683AlaTrp: 0.683 ± 0.0
2.732AlaTyr: 2.732 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.366CysAla: 1.366 ± 0.0
0.342CysCys: 0.342 ± 0.0
1.025CysAsp: 1.025 ± 0.0
0.683CysGlu: 0.683 ± 0.0
1.025CysPhe: 1.025 ± 0.0
1.366CysGly: 1.366 ± 0.0
0.683CysHis: 0.683 ± 0.0
1.366CysIle: 1.366 ± 0.0
1.025CysLys: 1.025 ± 0.0
1.025CysLeu: 1.025 ± 0.0
0.342CysMet: 0.342 ± 0.0
0.683CysAsn: 0.683 ± 0.0
1.366CysPro: 1.366 ± 0.0
1.025CysGln: 1.025 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.366CysSer: 1.366 ± 0.0
1.366CysThr: 1.366 ± 0.0
0.683CysVal: 0.683 ± 0.0
0.342CysTrp: 0.342 ± 0.0
0.683CysTyr: 0.683 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.366AspAla: 1.366 ± 0.0
2.049AspCys: 2.049 ± 0.0
4.44AspAsp: 4.44 ± 0.0
3.757AspGlu: 3.757 ± 0.0
3.415AspPhe: 3.415 ± 0.0
2.391AspGly: 2.391 ± 0.0
1.025AspHis: 1.025 ± 0.0
3.757AspIle: 3.757 ± 0.0
2.049AspLys: 2.049 ± 0.0
2.732AspLeu: 2.732 ± 0.0
0.683AspMet: 0.683 ± 0.0
2.391AspAsn: 2.391 ± 0.0
3.415AspPro: 3.415 ± 0.0
1.025AspGln: 1.025 ± 0.0
1.366AspArg: 1.366 ± 0.0
3.757AspSer: 3.757 ± 0.0
1.708AspThr: 1.708 ± 0.0
2.391AspVal: 2.391 ± 0.0
0.683AspTrp: 0.683 ± 0.0
2.049AspTyr: 2.049 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.757GluAla: 3.757 ± 0.0
0.683GluCys: 0.683 ± 0.0
2.049GluAsp: 2.049 ± 0.0
4.44GluGlu: 4.44 ± 0.0
3.415GluPhe: 3.415 ± 0.0
5.464GluGly: 5.464 ± 0.0
1.366GluHis: 1.366 ± 0.0
5.123GluIle: 5.123 ± 0.0
2.391GluLys: 2.391 ± 0.0
4.44GluLeu: 4.44 ± 0.0
0.683GluMet: 0.683 ± 0.0
1.366GluAsn: 1.366 ± 0.0
2.391GluPro: 2.391 ± 0.0
1.366GluGln: 1.366 ± 0.0
3.415GluArg: 3.415 ± 0.0
5.464GluSer: 5.464 ± 0.0
3.415GluThr: 3.415 ± 0.0
3.757GluVal: 3.757 ± 0.0
0.683GluTrp: 0.683 ± 0.0
2.049GluTyr: 2.049 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.757PheAla: 3.757 ± 0.0
0.683PheCys: 0.683 ± 0.0
3.074PheAsp: 3.074 ± 0.0
3.757PheGlu: 3.757 ± 0.0
2.732PhePhe: 2.732 ± 0.0
3.415PheGly: 3.415 ± 0.0
1.708PheHis: 1.708 ± 0.0
2.049PheIle: 2.049 ± 0.0
2.049PheLys: 2.049 ± 0.0
4.44PheLeu: 4.44 ± 0.0
1.366PheMet: 1.366 ± 0.0
2.391PheAsn: 2.391 ± 0.0
2.732PhePro: 2.732 ± 0.0
2.391PheGln: 2.391 ± 0.0
1.708PheArg: 1.708 ± 0.0
5.464PheSer: 5.464 ± 0.0
1.366PheThr: 1.366 ± 0.0
3.415PheVal: 3.415 ± 0.0
1.025PheTrp: 1.025 ± 0.0
0.683PheTyr: 0.683 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.123GlyAla: 5.123 ± 0.0
1.366GlyCys: 1.366 ± 0.0
3.074GlyAsp: 3.074 ± 0.0
3.415GlyGlu: 3.415 ± 0.0
2.732GlyPhe: 2.732 ± 0.0
2.049GlyGly: 2.049 ± 0.0
1.708GlyHis: 1.708 ± 0.0
3.415GlyIle: 3.415 ± 0.0
1.708GlyLys: 1.708 ± 0.0
5.464GlyLeu: 5.464 ± 0.0
1.025GlyMet: 1.025 ± 0.0
1.366GlyAsn: 1.366 ± 0.0
4.098GlyPro: 4.098 ± 0.0
1.366GlyGln: 1.366 ± 0.0
1.366GlyArg: 1.366 ± 0.0
5.123GlySer: 5.123 ± 0.0
3.074GlyThr: 3.074 ± 0.0
5.806GlyVal: 5.806 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
3.757GlyTyr: 3.757 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.366HisAla: 1.366 ± 0.0
0.683HisCys: 0.683 ± 0.0
0.683HisAsp: 0.683 ± 0.0
1.708HisGlu: 1.708 ± 0.0
2.049HisPhe: 2.049 ± 0.0
1.366HisGly: 1.366 ± 0.0
0.683HisHis: 0.683 ± 0.0
1.025HisIle: 1.025 ± 0.0
0.683HisLys: 0.683 ± 0.0
3.415HisLeu: 3.415 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.342HisAsn: 0.342 ± 0.0
1.025HisPro: 1.025 ± 0.0
1.366HisGln: 1.366 ± 0.0
1.708HisArg: 1.708 ± 0.0
2.049HisSer: 2.049 ± 0.0
2.391HisThr: 2.391 ± 0.0
1.025HisVal: 1.025 ± 0.0
0.683HisTrp: 0.683 ± 0.0
1.025HisTyr: 1.025 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.757IleAla: 3.757 ± 0.0
0.683IleCys: 0.683 ± 0.0
2.732IleAsp: 2.732 ± 0.0
2.391IleGlu: 2.391 ± 0.0
2.391IlePhe: 2.391 ± 0.0
3.074IleGly: 3.074 ± 0.0
1.366IleHis: 1.366 ± 0.0
3.074IleIle: 3.074 ± 0.0
4.781IleLys: 4.781 ± 0.0
3.415IleLeu: 3.415 ± 0.0
2.391IleMet: 2.391 ± 0.0
2.049IleAsn: 2.049 ± 0.0
5.123IlePro: 5.123 ± 0.0
3.757IleGln: 3.757 ± 0.0
1.025IleArg: 1.025 ± 0.0
5.464IleSer: 5.464 ± 0.0
1.708IleThr: 1.708 ± 0.0
3.074IleVal: 3.074 ± 0.0
0.342IleTrp: 0.342 ± 0.0
3.074IleTyr: 3.074 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.098LysAla: 4.098 ± 0.0
1.025LysCys: 1.025 ± 0.0
3.415LysAsp: 3.415 ± 0.0
3.415LysGlu: 3.415 ± 0.0
2.391LysPhe: 2.391 ± 0.0
3.415LysGly: 3.415 ± 0.0
2.049LysHis: 2.049 ± 0.0
3.757LysIle: 3.757 ± 0.0
3.074LysLys: 3.074 ± 0.0
5.464LysLeu: 5.464 ± 0.0
0.683LysMet: 0.683 ± 0.0
2.391LysAsn: 2.391 ± 0.0
2.732LysPro: 2.732 ± 0.0
1.366LysGln: 1.366 ± 0.0
2.391LysArg: 2.391 ± 0.0
4.098LysSer: 4.098 ± 0.0
3.415LysThr: 3.415 ± 0.0
3.757LysVal: 3.757 ± 0.0
0.342LysTrp: 0.342 ± 0.0
3.074LysTyr: 3.074 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
7.855LeuAla: 7.855 ± 0.0
2.049LeuCys: 2.049 ± 0.0
1.025LeuAsp: 1.025 ± 0.0
4.781LeuGlu: 4.781 ± 0.0
3.757LeuPhe: 3.757 ± 0.0
4.098LeuGly: 4.098 ± 0.0
3.074LeuHis: 3.074 ± 0.0
3.415LeuIle: 3.415 ± 0.0
8.538LeuLys: 8.538 ± 0.0
8.88LeuLeu: 8.88 ± 0.0
2.049LeuMet: 2.049 ± 0.0
6.489LeuAsn: 6.489 ± 0.0
4.781LeuPro: 4.781 ± 0.0
1.708LeuGln: 1.708 ± 0.0
3.757LeuArg: 3.757 ± 0.0
9.904LeuSer: 9.904 ± 0.0
6.489LeuThr: 6.489 ± 0.0
4.098LeuVal: 4.098 ± 0.0
0.683LeuTrp: 0.683 ± 0.0
1.708LeuTyr: 1.708 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.708MetAla: 1.708 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.366MetGlu: 1.366 ± 0.0
0.342MetPhe: 0.342 ± 0.0
1.708MetGly: 1.708 ± 0.0
0.683MetHis: 0.683 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.683MetLys: 0.683 ± 0.0
3.415MetLeu: 3.415 ± 0.0
0.683MetMet: 0.683 ± 0.0
2.049MetAsn: 2.049 ± 0.0
2.049MetPro: 2.049 ± 0.0
0.342MetGln: 0.342 ± 0.0
1.708MetArg: 1.708 ± 0.0
3.074MetSer: 3.074 ± 0.0
1.366MetThr: 1.366 ± 0.0
1.025MetVal: 1.025 ± 0.0
0.342MetTrp: 0.342 ± 0.0
0.683MetTyr: 0.683 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.757AsnAla: 3.757 ± 0.0
0.342AsnCys: 0.342 ± 0.0
1.025AsnAsp: 1.025 ± 0.0
3.757AsnGlu: 3.757 ± 0.0
4.098AsnPhe: 4.098 ± 0.0
2.391AsnGly: 2.391 ± 0.0
1.366AsnHis: 1.366 ± 0.0
2.732AsnIle: 2.732 ± 0.0
4.098AsnLys: 4.098 ± 0.0
3.757AsnLeu: 3.757 ± 0.0
0.683AsnMet: 0.683 ± 0.0
5.123AsnAsn: 5.123 ± 0.0
3.415AsnPro: 3.415 ± 0.0
2.732AsnGln: 2.732 ± 0.0
3.074AsnArg: 3.074 ± 0.0
1.366AsnSer: 1.366 ± 0.0
3.415AsnThr: 3.415 ± 0.0
3.074AsnVal: 3.074 ± 0.0
1.025AsnTrp: 1.025 ± 0.0
1.708AsnTyr: 1.708 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.415ProAla: 3.415 ± 0.0
1.366ProCys: 1.366 ± 0.0
1.366ProAsp: 1.366 ± 0.0
2.732ProGlu: 2.732 ± 0.0
2.049ProPhe: 2.049 ± 0.0
3.757ProGly: 3.757 ± 0.0
1.708ProHis: 1.708 ± 0.0
3.074ProIle: 3.074 ± 0.0
3.415ProLys: 3.415 ± 0.0
5.806ProLeu: 5.806 ± 0.0
0.683ProMet: 0.683 ± 0.0
2.732ProAsn: 2.732 ± 0.0
3.757ProPro: 3.757 ± 0.0
1.708ProGln: 1.708 ± 0.0
1.025ProArg: 1.025 ± 0.0
5.464ProSer: 5.464 ± 0.0
4.781ProThr: 4.781 ± 0.0
2.391ProVal: 2.391 ± 0.0
1.025ProTrp: 1.025 ± 0.0
2.391ProTyr: 2.391 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.757GlnAla: 3.757 ± 0.0
0.342GlnCys: 0.342 ± 0.0
0.683GlnAsp: 0.683 ± 0.0
1.366GlnGlu: 1.366 ± 0.0
2.049GlnPhe: 2.049 ± 0.0
1.708GlnGly: 1.708 ± 0.0
0.342GlnHis: 0.342 ± 0.0
3.757GlnIle: 3.757 ± 0.0
1.025GlnLys: 1.025 ± 0.0
4.098GlnLeu: 4.098 ± 0.0
1.366GlnMet: 1.366 ± 0.0
3.074GlnAsn: 3.074 ± 0.0
2.049GlnPro: 2.049 ± 0.0
1.366GlnGln: 1.366 ± 0.0
1.366GlnArg: 1.366 ± 0.0
4.44GlnSer: 4.44 ± 0.0
2.732GlnThr: 2.732 ± 0.0
3.074GlnVal: 3.074 ± 0.0
0.342GlnTrp: 0.342 ± 0.0
0.683GlnTyr: 0.683 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.049ArgAla: 2.049 ± 0.0
0.683ArgCys: 0.683 ± 0.0
1.708ArgAsp: 1.708 ± 0.0
3.074ArgGlu: 3.074 ± 0.0
2.391ArgPhe: 2.391 ± 0.0
2.049ArgGly: 2.049 ± 0.0
1.366ArgHis: 1.366 ± 0.0
2.732ArgIle: 2.732 ± 0.0
1.708ArgLys: 1.708 ± 0.0
3.757ArgLeu: 3.757 ± 0.0
1.025ArgMet: 1.025 ± 0.0
2.732ArgAsn: 2.732 ± 0.0
1.366ArgPro: 1.366 ± 0.0
2.732ArgGln: 2.732 ± 0.0
3.415ArgArg: 3.415 ± 0.0
3.074ArgSer: 3.074 ± 0.0
4.781ArgThr: 4.781 ± 0.0
3.074ArgVal: 3.074 ± 0.0
0.342ArgTrp: 0.342 ± 0.0
2.049ArgTyr: 2.049 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.806SerAla: 5.806 ± 0.0
1.708SerCys: 1.708 ± 0.0
6.831SerAsp: 6.831 ± 0.0
3.415SerGlu: 3.415 ± 0.0
3.415SerPhe: 3.415 ± 0.0
4.098SerGly: 4.098 ± 0.0
1.366SerHis: 1.366 ± 0.0
4.781SerIle: 4.781 ± 0.0
4.44SerLys: 4.44 ± 0.0
7.855SerLeu: 7.855 ± 0.0
2.391SerMet: 2.391 ± 0.0
4.781SerAsn: 4.781 ± 0.0
3.757SerPro: 3.757 ± 0.0
3.415SerGln: 3.415 ± 0.0
3.415SerArg: 3.415 ± 0.0
6.148SerSer: 6.148 ± 0.0
7.514SerThr: 7.514 ± 0.0
5.464SerVal: 5.464 ± 0.0
1.708SerTrp: 1.708 ± 0.0
2.732SerTyr: 2.732 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.757ThrAla: 3.757 ± 0.0
0.683ThrCys: 0.683 ± 0.0
3.757ThrAsp: 3.757 ± 0.0
4.098ThrGlu: 4.098 ± 0.0
4.098ThrPhe: 4.098 ± 0.0
3.415ThrGly: 3.415 ± 0.0
0.342ThrHis: 0.342 ± 0.0
4.781ThrIle: 4.781 ± 0.0
4.098ThrLys: 4.098 ± 0.0
4.781ThrLeu: 4.781 ± 0.0
1.708ThrMet: 1.708 ± 0.0
3.074ThrAsn: 3.074 ± 0.0
3.757ThrPro: 3.757 ± 0.0
3.415ThrGln: 3.415 ± 0.0
5.464ThrArg: 5.464 ± 0.0
5.464ThrSer: 5.464 ± 0.0
4.44ThrThr: 4.44 ± 0.0
5.464ThrVal: 5.464 ± 0.0
1.366ThrTrp: 1.366 ± 0.0
1.366ThrTyr: 1.366 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.732ValAla: 2.732 ± 0.0
1.025ValCys: 1.025 ± 0.0
3.757ValAsp: 3.757 ± 0.0
5.806ValGlu: 5.806 ± 0.0
3.757ValPhe: 3.757 ± 0.0
3.074ValGly: 3.074 ± 0.0
1.366ValHis: 1.366 ± 0.0
1.708ValIle: 1.708 ± 0.0
3.074ValLys: 3.074 ± 0.0
4.44ValLeu: 4.44 ± 0.0
2.049ValMet: 2.049 ± 0.0
4.098ValAsn: 4.098 ± 0.0
2.049ValPro: 2.049 ± 0.0
3.415ValGln: 3.415 ± 0.0
2.049ValArg: 2.049 ± 0.0
4.781ValSer: 4.781 ± 0.0
5.464ValThr: 5.464 ± 0.0
3.415ValVal: 3.415 ± 0.0
0.0ValTrp: 0.0 ± 0.0
2.049ValTyr: 2.049 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.342TrpAsp: 0.342 ± 0.0
0.342TrpGlu: 0.342 ± 0.0
1.025TrpPhe: 1.025 ± 0.0
0.683TrpGly: 0.683 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.683TrpIle: 0.683 ± 0.0
0.683TrpLys: 0.683 ± 0.0
1.366TrpLeu: 1.366 ± 0.0
0.683TrpMet: 0.683 ± 0.0
0.683TrpAsn: 0.683 ± 0.0
0.342TrpPro: 0.342 ± 0.0
0.342TrpGln: 0.342 ± 0.0
1.708TrpArg: 1.708 ± 0.0
1.708TrpSer: 1.708 ± 0.0
0.683TrpThr: 0.683 ± 0.0
0.342TrpVal: 0.342 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.025TyrAla: 1.025 ± 0.0
0.683TyrCys: 0.683 ± 0.0
2.049TyrAsp: 2.049 ± 0.0
1.708TyrGlu: 1.708 ± 0.0
1.366TyrPhe: 1.366 ± 0.0
2.049TyrGly: 2.049 ± 0.0
1.366TyrHis: 1.366 ± 0.0
2.049TyrIle: 2.049 ± 0.0
1.366TyrLys: 1.366 ± 0.0
3.415TyrLeu: 3.415 ± 0.0
1.708TyrMet: 1.708 ± 0.0
2.391TyrAsn: 2.391 ± 0.0
1.366TyrPro: 1.366 ± 0.0
2.391TyrGln: 2.391 ± 0.0
2.049TyrArg: 2.049 ± 0.0
2.391TyrSer: 2.391 ± 0.0
3.074TyrThr: 3.074 ± 0.0
2.049TyrVal: 2.049 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.683TyrTyr: 0.683 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2929 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski