Amino acid dipepetide frequency for Modestobacter roseus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	25.018AlaAla: 25.018 ± 0.23	0.862AlaCys: 0.862 ± 0.023	9.746AlaAsp: 9.746 ± 0.101	9.36AlaGlu: 9.36 ± 0.124	3.33AlaPhe: 3.33 ± 0.053	16.212AlaGly: 16.212 ± 0.128	2.575AlaHis: 2.575 ± 0.052	3.579AlaIle: 3.579 ± 0.056	1.681AlaLys: 1.681 ± 0.041	15.448AlaLeu: 15.448 ± 0.143	2.501AlaMet: 2.501 ± 0.045	1.757AlaAsn: 1.757 ± 0.037	7.676AlaPro: 7.676 ± 0.121	3.972AlaGln: 3.972 ± 0.059	10.907AlaArg: 10.907 ± 0.116	5.504AlaSer: 5.504 ± 0.072	8.178AlaThr: 8.178 ± 0.097	14.621AlaVal: 14.621 ± 0.144	1.954AlaTrp: 1.954 ± 0.039	2.095AlaTyr: 2.095 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.882CysAla: 0.882 ± 0.025	0.078CysCys: 0.078 ± 0.008	0.406CysAsp: 0.406 ± 0.017	0.269CysGlu: 0.269 ± 0.014	0.169CysPhe: 0.169 ± 0.011	0.831CysGly: 0.831 ± 0.025	0.145CysHis: 0.145 ± 0.009	0.154CysIle: 0.154 ± 0.011	0.056CysLys: 0.056 ± 0.007	0.598CysLeu: 0.598 ± 0.021	0.086CysMet: 0.086 ± 0.009	0.09CysAsn: 0.09 ± 0.008	0.412CysPro: 0.412 ± 0.016	0.13CysGln: 0.13 ± 0.01	0.558CysArg: 0.558 ± 0.022	0.379CysSer: 0.379 ± 0.018	0.428CysThr: 0.428 ± 0.02	0.508CysVal: 0.508 ± 0.019	0.103CysTrp: 0.103 ± 0.01	0.106CysTyr: 0.106 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	8.672AspAla: 8.672 ± 0.093	0.335AspCys: 0.335 ± 0.016	4.455AspAsp: 4.455 ± 0.057	3.937AspGlu: 3.937 ± 0.061	1.335AspPhe: 1.335 ± 0.032	6.768AspGly: 6.768 ± 0.09	1.272AspHis: 1.272 ± 0.033	1.205AspIle: 1.205 ± 0.035	0.633AspLys: 0.633 ± 0.028	6.896AspLeu: 6.896 ± 0.079	0.699AspMet: 0.699 ± 0.025	0.66AspAsn: 0.66 ± 0.024	5.048AspPro: 5.048 ± 0.067	1.703AspGln: 1.703 ± 0.04	5.416AspArg: 5.416 ± 0.067	2.152AspSer: 2.152 ± 0.041	2.874AspThr: 2.874 ± 0.044	6.773AspVal: 6.773 ± 0.079	0.935AspTrp: 0.935 ± 0.025	0.963AspTyr: 0.963 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	6.833GluAla: 6.833 ± 0.102	0.289GluCys: 0.289 ± 0.015	2.631GluAsp: 2.631 ± 0.052	3.053GluGlu: 3.053 ± 0.054	1.365GluPhe: 1.365 ± 0.035	3.847GluGly: 3.847 ± 0.06	1.58GluHis: 1.58 ± 0.035	1.739GluIle: 1.739 ± 0.042	0.8GluLys: 0.8 ± 0.026	7.332GluLeu: 7.332 ± 0.086	0.751GluMet: 0.751 ± 0.026	0.753GluAsn: 0.753 ± 0.025	3.482GluPro: 3.482 ± 0.061	2.524GluGln: 2.524 ± 0.047	4.789GluArg: 4.789 ± 0.07	2.244GluSer: 2.244 ± 0.044	2.685GluThr: 2.685 ± 0.049	5.554GluVal: 5.554 ± 0.061	0.739GluTrp: 0.739 ± 0.025	0.916GluTyr: 0.916 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.665PheAla: 3.665 ± 0.059	0.219PheCys: 0.219 ± 0.013	1.886PheAsp: 1.886 ± 0.041	1.166PheGlu: 1.166 ± 0.032	0.811PhePhe: 0.811 ± 0.027	2.889PheGly: 2.889 ± 0.051	0.422PheHis: 0.422 ± 0.018	0.657PheIle: 0.657 ± 0.026	0.296PheLys: 0.296 ± 0.015	2.45PheLeu: 2.45 ± 0.045	0.31PheMet: 0.31 ± 0.016	0.401PheAsn: 0.401 ± 0.016	1.324PhePro: 1.324 ± 0.033	0.61PheGln: 0.61 ± 0.024	1.626PheArg: 1.626 ± 0.035	1.352PheSer: 1.352 ± 0.03	1.883PheThr: 1.883 ± 0.037	2.344PheVal: 2.344 ± 0.046	0.363PheTrp: 0.363 ± 0.018	0.489PheTyr: 0.489 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	12.405GlyAla: 12.405 ± 0.132	0.798GlyCys: 0.798 ± 0.023	5.674GlyAsp: 5.674 ± 0.073	5.276GlyGlu: 5.276 ± 0.066	2.797GlyPhe: 2.797 ± 0.054	9.223GlyGly: 9.223 ± 0.132	1.995GlyHis: 1.995 ± 0.041	3.116GlyIle: 3.116 ± 0.063	1.614GlyLys: 1.614 ± 0.043	10.243GlyLeu: 10.243 ± 0.107	2.031GlyMet: 2.031 ± 0.039	1.541GlyAsn: 1.541 ± 0.039	5.416GlyPro: 5.416 ± 0.07	2.94GlyGln: 2.94 ± 0.045	8.06GlyArg: 8.06 ± 0.091	5.507GlySer: 5.507 ± 0.06	6.229GlyThr: 6.229 ± 0.079	9.044GlyVal: 9.044 ± 0.097	1.975GlyTrp: 1.975 ± 0.046	2.091GlyTyr: 2.091 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.391HisAla: 2.391 ± 0.041	0.17HisCys: 0.17 ± 0.011	1.224HisAsp: 1.224 ± 0.029	1.048HisGlu: 1.048 ± 0.027	0.497HisPhe: 0.497 ± 0.023	2.07HisGly: 2.07 ± 0.045	0.563HisHis: 0.563 ± 0.022	0.365HisIle: 0.365 ± 0.016	0.183HisLys: 0.183 ± 0.011	2.309HisLeu: 2.309 ± 0.042	0.247HisMet: 0.247 ± 0.012	0.25HisAsn: 0.25 ± 0.015	1.716HisPro: 1.716 ± 0.036	0.557HisGln: 0.557 ± 0.02	1.941HisArg: 1.941 ± 0.04	0.784HisSer: 0.784 ± 0.024	1.015HisThr: 1.015 ± 0.032	1.861HisVal: 1.861 ± 0.041	0.302HisTrp: 0.302 ± 0.017	0.333HisTyr: 0.333 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	4.562IleAla: 4.562 ± 0.057	0.222IleCys: 0.222 ± 0.012	2.092IleAsp: 2.092 ± 0.042	1.703IleGlu: 1.703 ± 0.039	0.413IlePhe: 0.413 ± 0.019	3.442IleGly: 3.442 ± 0.056	0.329IleHis: 0.329 ± 0.016	0.654IleIle: 0.654 ± 0.03	0.425IleLys: 0.425 ± 0.02	1.494IleLeu: 1.494 ± 0.039	0.326IleMet: 0.326 ± 0.016	0.538IleAsn: 0.538 ± 0.02	1.37IlePro: 1.37 ± 0.035	0.552IleGln: 0.552 ± 0.022	1.724IleArg: 1.724 ± 0.036	1.574IleSer: 1.574 ± 0.038	1.924IleThr: 1.924 ± 0.042	2.389IleVal: 2.389 ± 0.055	0.319IleTrp: 0.319 ± 0.016	0.393IleTyr: 0.393 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	1.723LysAla: 1.723 ± 0.044	0.046LysCys: 0.046 ± 0.006	0.751LysAsp: 0.751 ± 0.027	0.63LysGlu: 0.63 ± 0.027	0.247LysPhe: 0.247 ± 0.015	1.012LysGly: 1.012 ± 0.033	0.269LysHis: 0.269 ± 0.014	0.435LysIle: 0.435 ± 0.019	0.395LysLys: 0.395 ± 0.021	1.235LysLeu: 1.235 ± 0.034	0.224LysMet: 0.224 ± 0.014	0.276LysAsn: 0.276 ± 0.017	0.757LysPro: 0.757 ± 0.025	0.455LysGln: 0.455 ± 0.022	0.964LysArg: 0.964 ± 0.03	0.642LysSer: 0.642 ± 0.023	0.825LysThr: 0.825 ± 0.026	1.238LysVal: 1.238 ± 0.038	0.157LysTrp: 0.157 ± 0.01	0.26LysTyr: 0.26 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	17.521LeuAla: 17.521 ± 0.17	0.619LeuCys: 0.619 ± 0.022	6.992LeuAsp: 6.992 ± 0.069	4.458LeuGlu: 4.458 ± 0.07	2.461LeuPhe: 2.461 ± 0.048	10.156LeuGly: 10.156 ± 0.117	1.952LeuHis: 1.952 ± 0.037	2.573LeuIle: 2.573 ± 0.049	1.09LeuLys: 1.09 ± 0.029	12.126LeuLeu: 12.126 ± 0.149	1.318LeuMet: 1.318 ± 0.035	1.262LeuAsn: 1.262 ± 0.031	6.915LeuPro: 6.915 ± 0.075	2.654LeuGln: 2.654 ± 0.039	8.479LeuArg: 8.479 ± 0.092	5.04LeuSer: 5.04 ± 0.062	7.255LeuThr: 7.255 ± 0.081	11.283LeuVal: 11.283 ± 0.116	1.136LeuTrp: 1.136 ± 0.034	1.359LeuTyr: 1.359 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	2.146MetAla: 2.146 ± 0.046	0.099MetCys: 0.099 ± 0.008	0.756MetAsp: 0.756 ± 0.023	0.556MetGlu: 0.556 ± 0.021	0.326MetPhe: 0.326 ± 0.015	1.244MetGly: 1.244 ± 0.032	0.313MetHis: 0.313 ± 0.017	0.5MetIle: 0.5 ± 0.021	0.258MetLys: 0.258 ± 0.013	1.39MetLeu: 1.39 ± 0.035	0.205MetMet: 0.205 ± 0.012	0.298MetAsn: 0.298 ± 0.013	0.993MetPro: 0.993 ± 0.029	0.407MetGln: 0.407 ± 0.017	1.277MetArg: 1.277 ± 0.032	1.253MetSer: 1.253 ± 0.027	1.687MetThr: 1.687 ± 0.034	1.253MetVal: 1.253 ± 0.031	0.162MetTrp: 0.162 ± 0.011	0.228MetTyr: 0.228 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	1.886AsnAla: 1.886 ± 0.038	0.109AsnCys: 0.109 ± 0.009	0.835AsnAsp: 0.835 ± 0.028	0.649AsnGlu: 0.649 ± 0.022	0.363AsnPhe: 0.363 ± 0.018	1.459AsnGly: 1.459 ± 0.036	0.277AsnHis: 0.277 ± 0.014	0.426AsnIle: 0.426 ± 0.02	0.229AsnLys: 0.229 ± 0.014	1.36AsnLeu: 1.36 ± 0.033	0.222AsnMet: 0.222 ± 0.013	0.289AsnAsn: 0.289 ± 0.015	1.067AsnPro: 1.067 ± 0.027	0.43AsnGln: 0.43 ± 0.02	1.077AsnArg: 1.077 ± 0.031	0.668AsnSer: 0.668 ± 0.023	0.855AsnThr: 0.855 ± 0.028	1.299AsnVal: 1.299 ± 0.034	0.233AsnTrp: 0.233 ± 0.013	0.285AsnTyr: 0.285 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	10.289ProAla: 10.289 ± 0.135	0.257ProCys: 0.257 ± 0.015	4.743ProAsp: 4.743 ± 0.064	4.141ProGlu: 4.141 ± 0.061	1.55ProPhe: 1.55 ± 0.036	7.029ProGly: 7.029 ± 0.08	1.125ProHis: 1.125 ± 0.033	1.324ProIle: 1.324 ± 0.033	0.639ProLys: 0.639 ± 0.023	5.364ProLeu: 5.364 ± 0.072	0.957ProMet: 0.957 ± 0.025	0.733ProAsn: 0.733 ± 0.023	3.728ProPro: 3.728 ± 0.081	1.528ProGln: 1.528 ± 0.04	4.083ProArg: 4.083 ± 0.061	2.844ProSer: 2.844 ± 0.048	3.75ProThr: 3.75 ± 0.074	6.457ProVal: 6.457 ± 0.079	0.971ProTrp: 0.971 ± 0.032	0.921ProTyr: 0.921 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.969GlnAla: 3.969 ± 0.064	0.145GlnCys: 0.145 ± 0.011	1.172GlnAsp: 1.172 ± 0.033	1.348GlnGlu: 1.348 ± 0.036	0.731GlnPhe: 0.731 ± 0.022	2.072GlnGly: 2.072 ± 0.044	0.6GlnHis: 0.6 ± 0.024	0.835GlnIle: 0.835 ± 0.025	0.362GlnLys: 0.362 ± 0.018	3.813GlnLeu: 3.813 ± 0.051	0.404GlnMet: 0.404 ± 0.018	0.381GlnAsn: 0.381 ± 0.019	1.767GlnPro: 1.767 ± 0.038	1.321GlnGln: 1.321 ± 0.036	2.626GlnArg: 2.626 ± 0.048	1.128GlnSer: 1.128 ± 0.031	1.477GlnThr: 1.477 ± 0.031	3.141GlnVal: 3.141 ± 0.046	0.416GlnTrp: 0.416 ± 0.019	0.503GlnTyr: 0.503 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	10.712ArgAla: 10.712 ± 0.11	0.52ArgCys: 0.52 ± 0.022	4.389ArgAsp: 4.389 ± 0.064	4.317ArgGlu: 4.317 ± 0.056	2.219ArgPhe: 2.219 ± 0.039	6.063ArgGly: 6.063 ± 0.08	1.708ArgHis: 1.708 ± 0.038	2.455ArgIle: 2.455 ± 0.05	0.993ArgLys: 0.993 ± 0.032	8.586ArgLeu: 8.586 ± 0.098	1.702ArgMet: 1.702 ± 0.032	1.091ArgAsn: 1.091 ± 0.031	5.27ArgPro: 5.27 ± 0.073	2.282ArgGln: 2.282 ± 0.043	8.074ArgArg: 8.074 ± 0.112	4.224ArgSer: 4.224 ± 0.053	5.039ArgThr: 5.039 ± 0.061	6.909ArgVal: 6.909 ± 0.082	1.595ArgTrp: 1.595 ± 0.037	1.553ArgTyr: 1.553 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.706SerAla: 6.706 ± 0.069	0.307SerCys: 0.307 ± 0.015	2.498SerAsp: 2.498 ± 0.047	1.976SerGlu: 1.976 ± 0.042	1.391SerPhe: 1.391 ± 0.025	5.317SerGly: 5.317 ± 0.068	0.797SerHis: 0.797 ± 0.022	1.508SerIle: 1.508 ± 0.032	0.608SerLys: 0.608 ± 0.022	4.618SerLeu: 4.618 ± 0.065	0.947SerMet: 0.947 ± 0.025	0.731SerAsn: 0.731 ± 0.024	3.256SerPro: 3.256 ± 0.055	1.15SerGln: 1.15 ± 0.033	3.616SerArg: 3.616 ± 0.056	2.791SerSer: 2.791 ± 0.057	3.285SerThr: 3.285 ± 0.057	4.251SerVal: 4.251 ± 0.057	0.918SerTrp: 0.918 ± 0.029	0.996SerTyr: 0.996 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	9.458ThrAla: 9.458 ± 0.109	0.373ThrCys: 0.373 ± 0.017	4.043ThrAsp: 4.043 ± 0.063	3.275ThrGlu: 3.275 ± 0.052	1.528ThrPhe: 1.528 ± 0.036	7.191ThrGly: 7.191 ± 0.086	1.041ThrHis: 1.041 ± 0.03	1.698ThrIle: 1.698 ± 0.036	0.748ThrLys: 0.748 ± 0.026	5.667ThrLeu: 5.667 ± 0.058	0.839ThrMet: 0.839 ± 0.025	0.891ThrAsn: 0.891 ± 0.024	4.294ThrPro: 4.294 ± 0.079	1.321ThrGln: 1.321 ± 0.033	4.094ThrArg: 4.094 ± 0.061	3.171ThrSer: 3.171 ± 0.059	4.328ThrThr: 4.328 ± 0.085	6.52ThrVal: 6.52 ± 0.074	0.921ThrTrp: 0.921 ± 0.027	1.067ThrTyr: 1.067 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	13.973ValAla: 13.973 ± 0.132	0.672ValCys: 0.672 ± 0.023	6.435ValAsp: 6.435 ± 0.075	5.155ValGlu: 5.155 ± 0.059	2.663ValPhe: 2.663 ± 0.047	8.308ValGly: 8.308 ± 0.088	2.271ValHis: 2.271 ± 0.044	2.539ValIle: 2.539 ± 0.048	1.149ValLys: 1.149 ± 0.035	11.984ValLeu: 11.984 ± 0.126	1.198ValMet: 1.198 ± 0.029	1.517ValAsn: 1.517 ± 0.035	6.17ValPro: 6.17 ± 0.071	2.627ValGln: 2.627 ± 0.047	7.571ValArg: 7.571 ± 0.093	4.648ValSer: 4.648 ± 0.057	6.702ValThr: 6.702 ± 0.08	11.649ValVal: 11.649 ± 0.121	1.14ValTrp: 1.14 ± 0.025	1.513ValTyr: 1.513 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.879TrpAla: 1.879 ± 0.043	0.139TrpCys: 0.139 ± 0.01	0.795TrpAsp: 0.795 ± 0.025	0.646TrpGlu: 0.646 ± 0.023	0.5TrpPhe: 0.5 ± 0.023	1.096TrpGly: 1.096 ± 0.034	0.348TrpHis: 0.348 ± 0.018	0.368TrpIle: 0.368 ± 0.018	0.169TrpLys: 0.169 ± 0.011	1.904TrpLeu: 1.904 ± 0.042	0.224TrpMet: 0.224 ± 0.013	0.277TrpAsn: 0.277 ± 0.015	0.871TrpPro: 0.871 ± 0.026	0.559TrpGln: 0.559 ± 0.021	1.318TrpArg: 1.318 ± 0.033	0.953TrpSer: 0.953 ± 0.026	1.027TrpThr: 1.027 ± 0.027	1.212TrpVal: 1.212 ± 0.028	0.381TrpTrp: 0.381 ± 0.02	0.304TrpTyr: 0.304 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.288TyrAla: 2.288 ± 0.046	0.128TyrCys: 0.128 ± 0.009	1.211TyrAsp: 1.211 ± 0.042	0.941TyrGlu: 0.941 ± 0.023	0.468TyrPhe: 0.468 ± 0.019	1.746TyrGly: 1.746 ± 0.042	0.244TyrHis: 0.244 ± 0.014	0.315TyrIle: 0.315 ± 0.019	0.211TyrLys: 0.211 ± 0.014	1.831TyrLeu: 1.831 ± 0.037	0.161TyrMet: 0.161 ± 0.01	0.282TyrAsn: 0.282 ± 0.018	0.902TyrPro: 0.902 ± 0.028	0.487TyrGln: 0.487 ± 0.02	1.5TyrArg: 1.5 ± 0.032	0.809TyrSer: 0.809 ± 0.026	1.021TyrThr: 1.021 ± 0.033	1.58TyrVal: 1.58 ± 0.038	0.25TyrTrp: 0.25 ± 0.013	0.31TyrTyr: 0.31 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4272 proteins (1363073 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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