Amino acid dipepetide frequency for Pseudocercospora musae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.714AlaAla: 9.714 ± 0.066	1.206AlaCys: 1.206 ± 0.016	4.479AlaAsp: 4.479 ± 0.032	5.593AlaGlu: 5.593 ± 0.046	3.27AlaPhe: 3.27 ± 0.028	5.991AlaGly: 5.991 ± 0.034	1.976AlaHis: 1.976 ± 0.024	4.373AlaIle: 4.373 ± 0.032	4.54AlaLys: 4.54 ± 0.032	7.793AlaLeu: 7.793 ± 0.044	2.138AlaMet: 2.138 ± 0.025	3.158AlaAsn: 3.158 ± 0.024	5.018AlaPro: 5.018 ± 0.04	3.862AlaGln: 3.862 ± 0.035	5.313AlaArg: 5.313 ± 0.038	7.762AlaSer: 7.762 ± 0.051	5.56AlaThr: 5.56 ± 0.037	5.425AlaVal: 5.425 ± 0.037	1.262AlaTrp: 1.262 ± 0.016	2.299AlaTyr: 2.299 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.041CysAla: 1.041 ± 0.015	0.283CysCys: 0.283 ± 0.008	0.701CysAsp: 0.701 ± 0.013	0.663CysGlu: 0.663 ± 0.011	0.574CysPhe: 0.574 ± 0.011	0.979CysGly: 0.979 ± 0.017	0.373CysHis: 0.373 ± 0.009	0.736CysIle: 0.736 ± 0.012	0.588CysLys: 0.588 ± 0.012	1.264CysLeu: 1.264 ± 0.018	0.309CysMet: 0.309 ± 0.007	0.474CysAsn: 0.474 ± 0.011	0.702CysPro: 0.702 ± 0.014	0.467CysGln: 0.467 ± 0.01	0.82CysArg: 0.82 ± 0.014	1.037CysSer: 1.037 ± 0.016	0.79CysThr: 0.79 ± 0.013	0.803CysVal: 0.803 ± 0.014	0.221CysTrp: 0.221 ± 0.006	0.398CysTyr: 0.398 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.99AspAla: 4.99 ± 0.034	0.686AspCys: 0.686 ± 0.011	4.349AspAsp: 4.349 ± 0.044	4.404AspGlu: 4.404 ± 0.042	2.262AspPhe: 2.262 ± 0.021	4.101AspGly: 4.101 ± 0.033	1.358AspHis: 1.358 ± 0.018	2.86AspIle: 2.86 ± 0.023	2.276AspLys: 2.276 ± 0.024	5.019AspLeu: 5.019 ± 0.036	1.335AspMet: 1.335 ± 0.016	1.732AspAsn: 1.732 ± 0.02	3.076AspPro: 3.076 ± 0.022	2.065AspGln: 2.065 ± 0.021	3.15AspArg: 3.15 ± 0.026	4.099AspSer: 4.099 ± 0.035	2.971AspThr: 2.971 ± 0.026	3.619AspVal: 3.619 ± 0.027	0.915AspTrp: 0.915 ± 0.013	1.588AspTyr: 1.588 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.544GluAla: 5.544 ± 0.046	0.648GluCys: 0.648 ± 0.011	4.21GluAsp: 4.21 ± 0.034	5.274GluGlu: 5.274 ± 0.05	1.73GluPhe: 1.73 ± 0.02	3.638GluGly: 3.638 ± 0.029	1.673GluHis: 1.673 ± 0.02	2.812GluIle: 2.812 ± 0.024	3.728GluLys: 3.728 ± 0.033	5.107GluLeu: 5.107 ± 0.044	1.479GluMet: 1.479 ± 0.018	2.185GluAsn: 2.185 ± 0.022	2.776GluPro: 2.776 ± 0.028	2.839GluGln: 2.839 ± 0.025	4.095GluArg: 4.095 ± 0.037	4.105GluSer: 4.105 ± 0.033	3.26GluThr: 3.26 ± 0.03	3.484GluVal: 3.484 ± 0.028	0.865GluTrp: 0.865 ± 0.014	1.617GluTyr: 1.617 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.225PheAla: 3.225 ± 0.026	0.589PheCys: 0.589 ± 0.011	2.27PheAsp: 2.27 ± 0.021	2.147PheGlu: 2.147 ± 0.019	1.506PhePhe: 1.506 ± 0.019	2.896PheGly: 2.896 ± 0.028	0.894PheHis: 0.894 ± 0.014	1.574PheIle: 1.574 ± 0.022	1.454PheLys: 1.454 ± 0.018	3.147PheLeu: 3.147 ± 0.029	0.77PheMet: 0.77 ± 0.012	1.369PheAsn: 1.369 ± 0.017	1.767PhePro: 1.767 ± 0.018	1.322PheGln: 1.322 ± 0.015	1.87PheArg: 1.87 ± 0.02	2.75PheSer: 2.75 ± 0.025	2.089PheThr: 2.089 ± 0.022	2.271PheVal: 2.271 ± 0.021	0.647PheTrp: 0.647 ± 0.011	1.013PheTyr: 1.013 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.475GlyAla: 5.475 ± 0.039	0.901GlyCys: 0.901 ± 0.014	3.57GlyAsp: 3.57 ± 0.029	3.609GlyGlu: 3.609 ± 0.027	2.681GlyPhe: 2.681 ± 0.025	5.702GlyGly: 5.702 ± 0.058	1.79GlyHis: 1.79 ± 0.022	3.47GlyIle: 3.47 ± 0.026	3.578GlyLys: 3.578 ± 0.031	5.813GlyLeu: 5.813 ± 0.04	1.691GlyMet: 1.691 ± 0.017	2.54GlyAsn: 2.54 ± 0.025	3.211GlyPro: 3.211 ± 0.028	2.668GlyGln: 2.668 ± 0.029	4.137GlyArg: 4.137 ± 0.031	5.654GlySer: 5.654 ± 0.039	3.963GlyThr: 3.963 ± 0.032	4.104GlyVal: 4.104 ± 0.035	1.146GlyTrp: 1.146 ± 0.016	2.133GlyTyr: 2.133 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	2.201HisAla: 2.201 ± 0.021	0.404HisCys: 0.404 ± 0.009	1.49HisAsp: 1.49 ± 0.017	1.507HisGlu: 1.507 ± 0.018	1.013HisPhe: 1.013 ± 0.014	1.831HisGly: 1.831 ± 0.02	0.965HisHis: 0.965 ± 0.018	1.26HisIle: 1.26 ± 0.016	1.019HisLys: 1.019 ± 0.016	2.297HisLeu: 2.297 ± 0.022	0.545HisMet: 0.545 ± 0.011	0.905HisAsn: 0.905 ± 0.013	1.634HisPro: 1.634 ± 0.019	1.089HisGln: 1.089 ± 0.016	1.656HisArg: 1.656 ± 0.02	1.998HisSer: 1.998 ± 0.021	1.434HisThr: 1.434 ± 0.015	1.595HisVal: 1.595 ± 0.017	0.368HisTrp: 0.368 ± 0.008	0.743HisTyr: 0.743 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.417IleAla: 4.417 ± 0.032	0.792IleCys: 0.792 ± 0.014	2.906IleAsp: 2.906 ± 0.026	2.829IleGlu: 2.829 ± 0.03	1.83IlePhe: 1.83 ± 0.021	3.152IleGly: 3.152 ± 0.029	1.197IleHis: 1.197 ± 0.016	2.268IleIle: 2.268 ± 0.023	2.11IleLys: 2.11 ± 0.022	4.106IleLeu: 4.106 ± 0.037	1.032IleMet: 1.032 ± 0.014	1.765IleAsn: 1.765 ± 0.017	2.813IlePro: 2.813 ± 0.031	1.757IleGln: 1.757 ± 0.021	2.647IleArg: 2.647 ± 0.023	3.669IleSer: 3.669 ± 0.029	2.766IleThr: 2.766 ± 0.027	3.045IleVal: 3.045 ± 0.031	0.728IleTrp: 0.728 ± 0.012	1.338IleTyr: 1.338 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.654LysAla: 4.654 ± 0.042	0.542LysCys: 0.542 ± 0.011	2.885LysAsp: 2.885 ± 0.025	3.321LysGlu: 3.321 ± 0.036	1.379LysPhe: 1.379 ± 0.018	2.9LysGly: 2.9 ± 0.028	1.337LysHis: 1.337 ± 0.019	2.191LysIle: 2.191 ± 0.02	3.446LysLys: 3.446 ± 0.048	4.041LysLeu: 4.041 ± 0.03	1.105LysMet: 1.105 ± 0.015	1.714LysAsn: 1.714 ± 0.016	2.76LysPro: 2.76 ± 0.026	2.201LysGln: 2.201 ± 0.021	3.646LysArg: 3.646 ± 0.033	3.532LysSer: 3.532 ± 0.037	2.804LysThr: 2.804 ± 0.026	2.779LysVal: 2.779 ± 0.021	0.702LysTrp: 0.702 ± 0.012	1.318LysTyr: 1.318 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.848LeuAla: 7.848 ± 0.044	1.235LeuCys: 1.235 ± 0.02	4.932LeuAsp: 4.932 ± 0.037	5.277LeuGlu: 5.277 ± 0.039	3.048LeuPhe: 3.048 ± 0.027	5.608LeuGly: 5.608 ± 0.037	2.389LeuHis: 2.389 ± 0.02	3.644LeuIle: 3.644 ± 0.037	4.089LeuLys: 4.089 ± 0.035	7.879LeuLeu: 7.879 ± 0.063	1.751LeuMet: 1.751 ± 0.022	3.019LeuAsn: 3.019 ± 0.022	5.549LeuPro: 5.549 ± 0.04	3.882LeuGln: 3.882 ± 0.034	5.702LeuArg: 5.702 ± 0.038	6.754LeuSer: 6.754 ± 0.042	4.662LeuThr: 4.662 ± 0.034	4.982LeuVal: 4.982 ± 0.039	1.162LeuTrp: 1.162 ± 0.015	2.235LeuTyr: 2.235 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.343MetAla: 2.343 ± 0.021	0.278MetCys: 0.278 ± 0.008	1.245MetAsp: 1.245 ± 0.018	1.24MetGlu: 1.24 ± 0.018	0.74MetPhe: 0.74 ± 0.011	1.391MetGly: 1.391 ± 0.018	0.592MetHis: 0.592 ± 0.011	1.009MetIle: 1.009 ± 0.013	1.027MetLys: 1.027 ± 0.013	2.032MetLeu: 2.032 ± 0.022	0.581MetMet: 0.581 ± 0.012	0.846MetAsn: 0.846 ± 0.014	1.519MetPro: 1.519 ± 0.017	1.024MetGln: 1.024 ± 0.017	1.388MetArg: 1.388 ± 0.015	1.942MetSer: 1.942 ± 0.019	1.306MetThr: 1.306 ± 0.017	1.228MetVal: 1.228 ± 0.018	0.27MetTrp: 0.27 ± 0.007	0.553MetTyr: 0.553 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.512AsnAla: 3.512 ± 0.029	0.463AsnCys: 0.463 ± 0.011	2.098AsnAsp: 2.098 ± 0.022	2.004AsnGlu: 2.004 ± 0.021	1.37AsnPhe: 1.37 ± 0.019	3.209AsnGly: 3.209 ± 0.033	0.904AsnHis: 0.904 ± 0.014	1.925AsnIle: 1.925 ± 0.021	1.507AsnLys: 1.507 ± 0.019	3.03AsnLeu: 3.03 ± 0.026	0.874AsnMet: 0.874 ± 0.014	1.496AsnAsn: 1.496 ± 0.025	2.176AsnPro: 2.176 ± 0.023	1.31AsnGln: 1.31 ± 0.015	1.892AsnArg: 1.892 ± 0.018	2.669AsnSer: 2.669 ± 0.026	2.261AsnThr: 2.261 ± 0.024	2.364AsnVal: 2.364 ± 0.021	0.535AsnTrp: 0.535 ± 0.01	1.007AsnTyr: 1.007 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.546ProAla: 5.546 ± 0.047	0.57ProCys: 0.57 ± 0.011	3.113ProAsp: 3.113 ± 0.028	3.683ProGlu: 3.683 ± 0.032	1.962ProPhe: 1.962 ± 0.022	3.9ProGly: 3.9 ± 0.033	1.45ProHis: 1.45 ± 0.019	2.459ProIle: 2.459 ± 0.022	2.758ProLys: 2.758 ± 0.025	4.432ProLeu: 4.432 ± 0.034	1.15ProMet: 1.15 ± 0.016	2.219ProAsn: 2.219 ± 0.022	5.281ProPro: 5.281 ± 0.065	2.594ProGln: 2.594 ± 0.033	3.423ProArg: 3.423 ± 0.031	5.871ProSer: 5.871 ± 0.046	3.978ProThr: 3.978 ± 0.035	3.291ProVal: 3.291 ± 0.027	0.714ProTrp: 0.714 ± 0.012	1.559ProTyr: 1.559 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.891GlnAla: 3.891 ± 0.031	0.531GlnCys: 0.531 ± 0.01	2.258GlnAsp: 2.258 ± 0.023	2.502GlnGlu: 2.502 ± 0.024	1.201GlnPhe: 1.201 ± 0.016	2.42GlnGly: 2.42 ± 0.021	1.359GlnHis: 1.359 ± 0.017	1.889GlnIle: 1.889 ± 0.02	2.161GlnLys: 2.161 ± 0.023	3.494GlnLeu: 3.494 ± 0.029	0.978GlnMet: 0.978 ± 0.015	1.675GlnAsn: 1.675 ± 0.019	2.737GlnPro: 2.737 ± 0.034	2.884GlnGln: 2.884 ± 0.043	2.949GlnArg: 2.949 ± 0.029	3.319GlnSer: 3.319 ± 0.032	2.445GlnThr: 2.445 ± 0.022	2.213GlnVal: 2.213 ± 0.023	0.608GlnTrp: 0.608 ± 0.009	1.302GlnTyr: 1.302 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	5.005ArgAla: 5.005 ± 0.032	0.8ArgCys: 0.8 ± 0.013	3.446ArgAsp: 3.446 ± 0.031	3.837ArgGlu: 3.837 ± 0.035	2.048ArgPhe: 2.048 ± 0.023	3.629ArgGly: 3.629 ± 0.032	1.7ArgHis: 1.7 ± 0.018	2.877ArgIle: 2.877 ± 0.025	3.714ArgLys: 3.714 ± 0.034	5.35ArgLeu: 5.35 ± 0.037	1.408ArgMet: 1.408 ± 0.016	2.323ArgAsn: 2.323 ± 0.021	3.719ArgPro: 3.719 ± 0.035	2.986ArgGln: 2.986 ± 0.027	5.195ArgArg: 5.195 ± 0.046	5.112ArgSer: 5.112 ± 0.045	3.422ArgThr: 3.422 ± 0.026	3.191ArgVal: 3.191 ± 0.026	0.914ArgTrp: 0.914 ± 0.013	1.653ArgTyr: 1.653 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	7.141SerAla: 7.141 ± 0.043	0.965SerCys: 0.965 ± 0.016	4.179SerAsp: 4.179 ± 0.029	4.125SerGlu: 4.125 ± 0.03	2.8SerPhe: 2.8 ± 0.024	5.617SerGly: 5.617 ± 0.038	2.007SerHis: 2.007 ± 0.019	3.938SerIle: 3.938 ± 0.033	3.835SerLys: 3.835 ± 0.029	6.659SerLeu: 6.659 ± 0.044	1.873SerMet: 1.873 ± 0.021	3.093SerAsn: 3.093 ± 0.024	5.325SerPro: 5.325 ± 0.052	3.349SerGln: 3.349 ± 0.031	5.251SerArg: 5.251 ± 0.044	8.661SerSer: 8.661 ± 0.073	5.704SerThr: 5.704 ± 0.047	4.303SerVal: 4.303 ± 0.033	1.135SerTrp: 1.135 ± 0.016	2.059SerTyr: 2.059 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.58ThrAla: 5.58 ± 0.035	0.83ThrCys: 0.83 ± 0.015	2.712ThrAsp: 2.712 ± 0.023	2.958ThrGlu: 2.958 ± 0.026	2.296ThrPhe: 2.296 ± 0.024	4.057ThrGly: 4.057 ± 0.036	1.33ThrHis: 1.33 ± 0.017	3.121ThrIle: 3.121 ± 0.031	2.673ThrLys: 2.673 ± 0.025	5.067ThrLeu: 5.067 ± 0.034	1.272ThrMet: 1.272 ± 0.015	2.177ThrAsn: 2.177 ± 0.026	4.355ThrPro: 4.355 ± 0.036	2.19ThrGln: 2.19 ± 0.021	3.208ThrArg: 3.208 ± 0.028	5.629ThrSer: 5.629 ± 0.05	4.457ThrThr: 4.457 ± 0.054	3.439ThrVal: 3.439 ± 0.032	0.877ThrTrp: 0.877 ± 0.016	1.633ThrTyr: 1.633 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.233ValAla: 5.233 ± 0.034	0.823ValCys: 0.823 ± 0.013	3.523ValAsp: 3.523 ± 0.027	3.736ValGlu: 3.736 ± 0.03	2.197ValPhe: 2.197 ± 0.025	3.833ValGly: 3.833 ± 0.031	1.44ValHis: 1.44 ± 0.018	2.664ValIle: 2.664 ± 0.025	2.884ValLys: 2.884 ± 0.026	5.291ValLeu: 5.291 ± 0.037	1.283ValMet: 1.283 ± 0.018	2.163ValAsn: 2.163 ± 0.021	3.432ValPro: 3.432 ± 0.037	2.455ValGln: 2.455 ± 0.022	3.386ValArg: 3.386 ± 0.025	4.328ValSer: 4.328 ± 0.031	3.366ValThr: 3.366 ± 0.029	3.992ValVal: 3.992 ± 0.035	0.848ValTrp: 0.848 ± 0.014	1.609ValTyr: 1.609 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.086TrpAla: 1.086 ± 0.013	0.215TrpCys: 0.215 ± 0.006	0.824TrpAsp: 0.824 ± 0.012	0.792TrpGlu: 0.792 ± 0.011	0.52TrpPhe: 0.52 ± 0.01	0.795TrpGly: 0.795 ± 0.014	0.418TrpHis: 0.418 ± 0.009	0.776TrpIle: 0.776 ± 0.013	0.794TrpLys: 0.794 ± 0.011	1.389TrpLeu: 1.389 ± 0.019	0.377TrpMet: 0.377 ± 0.008	0.627TrpAsn: 0.627 ± 0.013	0.669TrpPro: 0.669 ± 0.012	0.696TrpGln: 0.696 ± 0.011	1.016TrpArg: 1.016 ± 0.013	1.144TrpSer: 1.144 ± 0.018	0.989TrpThr: 0.989 ± 0.014	0.762TrpVal: 0.762 ± 0.012	0.273TrpTrp: 0.273 ± 0.008	0.462TrpTyr: 0.462 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.286TyrAla: 2.286 ± 0.019	0.459TyrCys: 0.459 ± 0.009	1.667TyrAsp: 1.667 ± 0.018	1.567TyrGlu: 1.567 ± 0.019	1.142TyrPhe: 1.142 ± 0.017	2.187TyrGly: 2.187 ± 0.022	0.802TyrHis: 0.802 ± 0.013	1.319TyrIle: 1.319 ± 0.015	1.075TyrLys: 1.075 ± 0.015	2.44TyrLeu: 2.44 ± 0.021	0.605TyrMet: 0.605 ± 0.009	1.128TyrAsn: 1.128 ± 0.014	1.433TyrPro: 1.433 ± 0.018	1.177TyrGln: 1.177 ± 0.014	1.584TyrArg: 1.584 ± 0.017	1.984TyrSer: 1.984 ± 0.021	1.631TyrThr: 1.631 ± 0.022	1.597TyrVal: 1.597 ± 0.017	0.437TyrTrp: 0.437 ± 0.01	0.924TyrTyr: 0.924 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11907 proteins (5423413 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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