Amino acid dipepetide frequency for Amasya cherry disease-associated mycovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.669AlaAla: 2.669 ± 1.853
0.0AlaCys: 0.0 ± 0.0
3.559AlaAsp: 3.559 ± 0.886
2.669AlaGlu: 2.669 ± 0.385
0.89AlaPhe: 0.89 ± 0.501
5.338AlaGly: 5.338 ± 0.349
3.559AlaHis: 3.559 ± 0.886
3.559AlaIle: 3.559 ± 0.886
2.669AlaLys: 2.669 ± 0.385
2.669AlaLeu: 2.669 ± 0.385
4.448AlaMet: 4.448 ± 1.387
5.338AlaAsn: 5.338 ± 1.468
8.897AlaPro: 8.897 ± 3.938
2.669AlaGln: 2.669 ± 0.385
1.779AlaArg: 1.779 ± 0.116
3.559AlaSer: 3.559 ± 1.351
8.897AlaThr: 8.897 ± 2.819
3.559AlaVal: 3.559 ± 1.351
0.0AlaTrp: 0.0 ± 0.0
2.669AlaTyr: 2.669 ± 1.503
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.89CysGlu: 0.89 ± 0.501
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.89CysHis: 0.89 ± 0.501
1.779CysIle: 1.779 ± 1.002
0.0CysLys: 0.0 ± 0.0
0.89CysLeu: 0.89 ± 0.501
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.89CysSer: 0.89 ± 0.501
0.89CysThr: 0.89 ± 0.618
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.559AspAla: 3.559 ± 0.886
0.0AspCys: 0.0 ± 0.0
5.338AspAsp: 5.338 ± 0.349
2.669AspGlu: 2.669 ± 0.385
6.228AspPhe: 6.228 ± 0.152
1.779AspGly: 1.779 ± 0.116
2.669AspHis: 2.669 ± 1.503
4.448AspIle: 4.448 ± 1.969
2.669AspLys: 2.669 ± 0.385
3.559AspLeu: 3.559 ± 1.351
0.0AspMet: 0.0 ± 0.0
2.669AspAsn: 2.669 ± 1.503
1.779AspPro: 1.779 ± 1.002
2.669AspGln: 2.669 ± 1.853
0.89AspArg: 0.89 ± 0.618
6.228AspSer: 6.228 ± 0.152
8.007AspThr: 8.007 ± 2.202
3.559AspVal: 3.559 ± 0.233
4.448AspTrp: 4.448 ± 0.268
2.669AspTyr: 2.669 ± 1.503
0.0AspXaa: 0.0 ± 0.0
Glu
1.779GluAla: 1.779 ± 0.116
0.0GluCys: 0.0 ± 0.0
0.89GluAsp: 0.89 ± 0.501
1.779GluGlu: 1.779 ± 0.116
2.669GluPhe: 2.669 ± 1.853
0.0GluGly: 0.0 ± 0.0
1.779GluHis: 1.779 ± 0.116
2.669GluIle: 2.669 ± 1.503
0.89GluLys: 0.89 ± 0.501
3.559GluLeu: 3.559 ± 2.004
0.0GluMet: 0.0 ± 0.454
1.779GluAsn: 1.779 ± 0.116
2.669GluPro: 2.669 ± 0.385
1.779GluGln: 1.779 ± 1.235
3.559GluArg: 3.559 ± 2.004
0.89GluSer: 0.89 ± 0.501
3.559GluThr: 3.559 ± 2.004
1.779GluVal: 1.779 ± 1.002
0.0GluTrp: 0.0 ± 0.0
2.669GluTyr: 2.669 ± 1.503
0.0GluXaa: 0.0 ± 0.0
Phe
6.228PheAla: 6.228 ± 0.967
0.89PheCys: 0.89 ± 0.501
5.338PheAsp: 5.338 ± 3.007
3.559PheGlu: 3.559 ± 0.886
3.559PhePhe: 3.559 ± 1.351
7.117PheGly: 7.117 ± 1.584
0.0PheHis: 0.0 ± 0.0
1.779PheIle: 1.779 ± 0.116
3.559PheLys: 3.559 ± 1.351
7.117PheLeu: 7.117 ± 0.653
1.779PheMet: 1.779 ± 0.116
0.0PheAsn: 0.0 ± 0.0
1.779PhePro: 1.779 ± 1.002
2.669PheGln: 2.669 ± 0.734
2.669PheArg: 2.669 ± 0.385
3.559PheSer: 3.559 ± 0.886
3.559PheThr: 3.559 ± 0.233
3.559PheVal: 3.559 ± 0.233
0.0PheTrp: 0.0 ± 0.0
2.669PheTyr: 2.669 ± 0.734
0.0PheXaa: 0.0 ± 0.0
Gly
1.779GlyAla: 1.779 ± 0.116
1.779GlyCys: 1.779 ± 1.002
1.779GlyAsp: 1.779 ± 0.116
0.0GlyGlu: 0.0 ± 0.0
2.669GlyPhe: 2.669 ± 0.385
1.779GlyGly: 1.779 ± 0.116
0.89GlyHis: 0.89 ± 0.501
7.117GlyIle: 7.117 ± 2.703
0.0GlyLys: 0.0 ± 0.0
7.117GlyLeu: 7.117 ± 0.653
0.89GlyMet: 0.89 ± 0.618
4.448GlyAsn: 4.448 ± 0.268
5.338GlyPro: 5.338 ± 2.587
0.0GlyGln: 0.0 ± 0.0
0.0GlyArg: 0.0 ± 0.0
2.669GlySer: 2.669 ± 1.853
0.89GlyThr: 0.89 ± 0.618
1.779GlyVal: 1.779 ± 0.116
1.779GlyTrp: 1.779 ± 0.116
2.669GlyTyr: 2.669 ± 0.385
0.0GlyXaa: 0.0 ± 0.0
His
4.448HisAla: 4.448 ± 0.268
0.0HisCys: 0.0 ± 0.0
2.669HisAsp: 2.669 ± 0.385
2.669HisGlu: 2.669 ± 1.503
2.669HisPhe: 2.669 ± 1.503
1.779HisGly: 1.779 ± 0.116
1.779HisHis: 1.779 ± 1.002
0.89HisIle: 0.89 ± 0.501
1.779HisLys: 1.779 ± 1.002
4.448HisLeu: 4.448 ± 0.268
0.89HisMet: 0.89 ± 0.501
0.89HisAsn: 0.89 ± 0.618
0.89HisPro: 0.89 ± 0.618
0.0HisGln: 0.0 ± 0.0
4.448HisArg: 4.448 ± 2.505
2.669HisSer: 2.669 ± 0.385
4.448HisThr: 4.448 ± 0.85
2.669HisVal: 2.669 ± 0.385
0.0HisTrp: 0.0 ± 0.0
1.779HisTyr: 1.779 ± 1.002
0.0HisXaa: 0.0 ± 0.0
Ile
3.559IleAla: 3.559 ± 1.351
0.0IleCys: 0.0 ± 0.0
2.669IleAsp: 2.669 ± 1.503
0.0IleGlu: 0.0 ± 0.0
5.338IlePhe: 5.338 ± 1.468
1.779IleGly: 1.779 ± 0.116
1.779IleHis: 1.779 ± 0.116
3.559IleIle: 3.559 ± 2.004
3.559IleLys: 3.559 ± 0.886
5.338IleLeu: 5.338 ± 1.468
0.89IleMet: 0.89 ± 0.618
2.669IleAsn: 2.669 ± 0.734
6.228IlePro: 6.228 ± 0.967
0.0IleGln: 0.0 ± 0.0
2.669IleArg: 2.669 ± 0.385
5.338IleSer: 5.338 ± 3.705
6.228IleThr: 6.228 ± 1.27
1.779IleVal: 1.779 ± 1.002
0.89IleTrp: 0.89 ± 0.501
1.779IleTyr: 1.779 ± 1.002
0.0IleXaa: 0.0 ± 0.0
Lys
2.669LysAla: 2.669 ± 0.385
0.89LysCys: 0.89 ± 0.501
5.338LysAsp: 5.338 ± 0.349
1.779LysGlu: 1.779 ± 1.002
1.779LysPhe: 1.779 ± 1.002
0.0LysGly: 0.0 ± 0.0
1.779LysHis: 1.779 ± 0.116
2.669LysIle: 2.669 ± 0.385
2.669LysLys: 2.669 ± 0.385
1.779LysLeu: 1.779 ± 1.002
1.779LysMet: 1.779 ± 1.002
3.559LysAsn: 3.559 ± 1.351
0.89LysPro: 0.89 ± 0.501
0.89LysGln: 0.89 ± 0.618
2.669LysArg: 2.669 ± 0.385
4.448LysSer: 4.448 ± 0.268
2.669LysThr: 2.669 ± 1.503
3.559LysVal: 3.559 ± 0.233
0.89LysTrp: 0.89 ± 0.501
2.669LysTyr: 2.669 ± 0.734
0.0LysXaa: 0.0 ± 0.0
Leu
8.007LeuAla: 8.007 ± 2.273
0.0LeuCys: 0.0 ± 0.0
8.897LeuAsp: 8.897 ± 0.582
1.779LeuGlu: 1.779 ± 1.002
7.117LeuPhe: 7.117 ± 0.653
0.89LeuGly: 0.89 ± 0.618
3.559LeuHis: 3.559 ± 0.886
4.448LeuIle: 4.448 ± 0.85
2.669LeuLys: 2.669 ± 0.734
1.779LeuLeu: 1.779 ± 0.116
0.89LeuMet: 0.89 ± 0.501
4.448LeuAsn: 4.448 ± 0.268
7.117LeuPro: 7.117 ± 0.653
2.669LeuGln: 2.669 ± 1.503
4.448LeuArg: 4.448 ± 0.268
8.007LeuSer: 8.007 ± 1.154
4.448LeuThr: 4.448 ± 0.268
4.448LeuVal: 4.448 ± 0.85
2.669LeuTrp: 2.669 ± 0.385
3.559LeuTyr: 3.559 ± 0.886
0.0LeuXaa: 0.0 ± 0.0
Met
0.89MetAla: 0.89 ± 0.501
0.0MetCys: 0.0 ± 0.0
1.779MetAsp: 1.779 ± 0.116
0.0MetGlu: 0.0 ± 0.0
0.89MetPhe: 0.89 ± 0.501
0.89MetGly: 0.89 ± 0.501
0.89MetHis: 0.89 ± 0.501
1.779MetIle: 1.779 ± 0.116
0.89MetLys: 0.89 ± 0.501
7.117MetLeu: 7.117 ± 1.771
0.89MetMet: 0.89 ± 0.618
0.89MetAsn: 0.89 ± 0.501
0.0MetPro: 0.0 ± 0.0
0.89MetGln: 0.89 ± 0.618
2.669MetArg: 2.669 ± 0.385
0.89MetSer: 0.89 ± 0.618
0.0MetThr: 0.0 ± 0.0
0.89MetVal: 0.89 ± 0.618
0.0MetTrp: 0.0 ± 0.0
0.89MetTyr: 0.89 ± 0.501
0.0MetXaa: 0.0 ± 0.0
Asn
4.448AsnAla: 4.448 ± 0.85
0.89AsnCys: 0.89 ± 0.618
4.448AsnAsp: 4.448 ± 0.85
2.669AsnGlu: 2.669 ± 0.385
2.669AsnPhe: 2.669 ± 0.385
3.559AsnGly: 3.559 ± 0.886
3.559AsnHis: 3.559 ± 0.886
0.89AsnIle: 0.89 ± 0.618
4.448AsnLys: 4.448 ± 0.268
2.669AsnLeu: 2.669 ± 0.385
0.0AsnMet: 0.0 ± 0.0
1.779AsnAsn: 1.779 ± 1.002
3.559AsnPro: 3.559 ± 1.351
1.779AsnGln: 1.779 ± 0.116
2.669AsnArg: 2.669 ± 1.503
3.559AsnSer: 3.559 ± 0.233
1.779AsnThr: 1.779 ± 1.235
4.448AsnVal: 4.448 ± 0.85
0.0AsnTrp: 0.0 ± 0.0
0.89AsnTyr: 0.89 ± 0.501
0.0AsnXaa: 0.0 ± 0.0
Pro
7.117ProAla: 7.117 ± 2.703
0.89ProCys: 0.89 ± 0.501
6.228ProAsp: 6.228 ± 0.967
1.779ProGlu: 1.779 ± 0.116
3.559ProPhe: 3.559 ± 1.351
2.669ProGly: 2.669 ± 0.734
2.669ProHis: 2.669 ± 1.503
2.669ProIle: 2.669 ± 0.734
1.779ProLys: 1.779 ± 0.116
2.669ProLeu: 2.669 ± 0.385
2.669ProMet: 2.669 ± 1.503
5.338ProAsn: 5.338 ± 0.349
3.559ProPro: 3.559 ± 0.886
0.89ProGln: 0.89 ± 0.501
1.779ProArg: 1.779 ± 0.116
4.448ProSer: 4.448 ± 0.268
3.559ProThr: 3.559 ± 0.233
2.669ProVal: 2.669 ± 0.734
0.89ProTrp: 0.89 ± 0.501
3.559ProTyr: 3.559 ± 0.233
0.0ProXaa: 0.0 ± 0.0
Gln
1.779GlnAla: 1.779 ± 1.235
0.0GlnCys: 0.0 ± 0.0
0.89GlnAsp: 0.89 ± 0.618
1.779GlnGlu: 1.779 ± 1.002
2.669GlnPhe: 2.669 ± 0.734
1.779GlnGly: 1.779 ± 1.002
0.89GlnHis: 0.89 ± 0.501
0.0GlnIle: 0.0 ± 0.0
1.779GlnLys: 1.779 ± 0.116
4.448GlnLeu: 4.448 ± 0.85
1.779GlnMet: 1.779 ± 0.116
1.779GlnAsn: 1.779 ± 0.116
1.779GlnPro: 1.779 ± 0.116
0.0GlnGln: 0.0 ± 0.0
0.89GlnArg: 0.89 ± 0.618
3.559GlnSer: 3.559 ± 0.233
2.669GlnThr: 2.669 ± 1.853
3.559GlnVal: 3.559 ± 1.351
0.0GlnTrp: 0.0 ± 0.0
1.779GlnTyr: 1.779 ± 1.235
0.0GlnXaa: 0.0 ± 0.0
Arg
2.669ArgAla: 2.669 ± 1.503
0.0ArgCys: 0.0 ± 0.0
0.89ArgAsp: 0.89 ± 0.501
1.779ArgGlu: 1.779 ± 0.116
3.559ArgPhe: 3.559 ± 1.351
1.779ArgGly: 1.779 ± 0.116
2.669ArgHis: 2.669 ± 1.503
0.0ArgIle: 0.0 ± 0.0
1.779ArgLys: 1.779 ± 0.116
7.117ArgLeu: 7.117 ± 1.771
0.0ArgMet: 0.0 ± 0.0
3.559ArgAsn: 3.559 ± 0.886
3.559ArgPro: 3.559 ± 0.886
0.89ArgGln: 0.89 ± 0.618
2.669ArgArg: 2.669 ± 0.385
3.559ArgSer: 3.559 ± 0.886
5.338ArgThr: 5.338 ± 0.349
1.779ArgVal: 1.779 ± 0.116
0.89ArgTrp: 0.89 ± 0.501
3.559ArgTyr: 3.559 ± 0.233
0.0ArgXaa: 0.0 ± 0.0
Ser
6.228SerAla: 6.228 ± 0.967
0.89SerCys: 0.89 ± 0.501
5.338SerAsp: 5.338 ± 2.587
1.779SerGlu: 1.779 ± 0.116
3.559SerPhe: 3.559 ± 0.233
3.559SerGly: 3.559 ± 1.351
1.779SerHis: 1.779 ± 1.235
3.559SerIle: 3.559 ± 0.233
2.669SerLys: 2.669 ± 0.385
6.228SerLeu: 6.228 ± 0.152
0.89SerMet: 0.89 ± 0.618
3.559SerAsn: 3.559 ± 1.351
2.669SerPro: 2.669 ± 0.385
3.559SerGln: 3.559 ± 2.47
1.779SerArg: 1.779 ± 0.116
2.669SerSer: 2.669 ± 0.734
6.228SerThr: 6.228 ± 0.967
3.559SerVal: 3.559 ± 0.886
1.779SerTrp: 1.779 ± 1.002
6.228SerTyr: 6.228 ± 1.27
0.0SerXaa: 0.0 ± 0.0
Thr
5.338ThrAla: 5.338 ± 1.468
0.0ThrCys: 0.0 ± 0.0
8.007ThrAsp: 8.007 ± 1.083
2.669ThrGlu: 2.669 ± 0.734
2.669ThrPhe: 2.669 ± 1.503
5.338ThrGly: 5.338 ± 2.587
2.669ThrHis: 2.669 ± 0.385
5.338ThrIle: 5.338 ± 1.468
7.117ThrLys: 7.117 ± 1.771
4.448ThrLeu: 4.448 ± 0.85
3.559ThrMet: 3.559 ± 1.776
2.669ThrAsn: 2.669 ± 0.385
4.448ThrPro: 4.448 ± 0.268
5.338ThrGln: 5.338 ± 0.349
3.559ThrArg: 3.559 ± 1.351
5.338ThrSer: 5.338 ± 2.587
8.007ThrThr: 8.007 ± 5.558
5.338ThrVal: 5.338 ± 1.468
1.779ThrTrp: 1.779 ± 1.002
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.448ValAla: 4.448 ± 0.85
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
3.559ValGlu: 3.559 ± 0.886
4.448ValPhe: 4.448 ± 0.268
2.669ValGly: 2.669 ± 0.734
1.779ValHis: 1.779 ± 1.235
4.448ValIle: 4.448 ± 0.85
1.779ValLys: 1.779 ± 0.116
6.228ValLeu: 6.228 ± 0.152
0.89ValMet: 0.89 ± 0.618
3.559ValAsn: 3.559 ± 0.886
2.669ValPro: 2.669 ± 0.734
3.559ValGln: 3.559 ± 0.886
6.228ValArg: 6.228 ± 0.152
4.448ValSer: 4.448 ± 1.969
4.448ValThr: 4.448 ± 1.969
1.779ValVal: 1.779 ± 0.116
0.89ValTrp: 0.89 ± 0.618
0.89ValTyr: 0.89 ± 0.618
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.89TrpGlu: 0.89 ± 0.501
0.89TrpPhe: 0.89 ± 0.618
0.89TrpGly: 0.89 ± 0.501
2.669TrpHis: 2.669 ± 0.385
0.89TrpIle: 0.89 ± 0.501
0.89TrpLys: 0.89 ± 0.501
0.89TrpLeu: 0.89 ± 0.501
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.89TrpPro: 0.89 ± 0.501
1.779TrpGln: 1.779 ± 0.116
0.89TrpArg: 0.89 ± 0.618
0.89TrpSer: 0.89 ± 0.501
3.559TrpThr: 3.559 ± 0.886
0.0TrpVal: 0.0 ± 0.0
0.89TrpTrp: 0.89 ± 0.501
0.89TrpTyr: 0.89 ± 0.501
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.779TyrAla: 1.779 ± 1.002
0.0TyrCys: 0.0 ± 0.0
1.779TyrAsp: 1.779 ± 0.116
0.89TyrGlu: 0.89 ± 0.501
3.559TyrPhe: 3.559 ± 2.004
1.779TyrGly: 1.779 ± 0.116
3.559TyrHis: 3.559 ± 0.886
3.559TyrIle: 3.559 ± 0.886
1.779TyrLys: 1.779 ± 1.002
1.779TyrLeu: 1.779 ± 1.002
0.0TyrMet: 0.0 ± 0.0
1.779TyrAsn: 1.779 ± 0.116
2.669TyrPro: 2.669 ± 1.503
1.779TyrGln: 1.779 ± 1.235
1.779TyrArg: 1.779 ± 1.002
0.89TyrSer: 0.89 ± 0.618
4.448TyrThr: 4.448 ± 1.387
8.007TyrVal: 8.007 ± 2.202
0.0TyrTrp: 0.0 ± 0.0
4.448TyrTyr: 4.448 ± 0.268
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1125 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski