Amino acid dipepetide frequency for Shuttleworthia satelles DSM 14600

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.049AlaAla: 8.049 ± 0.142	1.201AlaCys: 1.201 ± 0.047	5.758AlaAsp: 5.758 ± 0.112	5.313AlaGlu: 5.313 ± 0.091	3.494AlaPhe: 3.494 ± 0.084	7.019AlaGly: 7.019 ± 0.13	1.323AlaHis: 1.323 ± 0.044	5.288AlaIle: 5.288 ± 0.096	4.578AlaLys: 4.578 ± 0.099	7.802AlaLeu: 7.802 ± 0.131	2.666AlaMet: 2.666 ± 0.073	2.937AlaAsn: 2.937 ± 0.079	2.179AlaPro: 2.179 ± 0.058	2.613AlaGln: 2.613 ± 0.079	5.033AlaArg: 5.033 ± 0.11	5.12AlaSer: 5.12 ± 0.098	3.134AlaThr: 3.134 ± 0.077	5.92AlaVal: 5.92 ± 0.103	0.682AlaTrp: 0.682 ± 0.033	2.921AlaTyr: 2.921 ± 0.071	0.0AlaXaa: 0.0 ± 0.0
Cys	0.969CysAla: 0.969 ± 0.045	0.209CysCys: 0.209 ± 0.019	0.781CysAsp: 0.781 ± 0.038	0.664CysGlu: 0.664 ± 0.037	0.611CysPhe: 0.611 ± 0.033	1.294CysGly: 1.294 ± 0.045	0.387CysHis: 0.387 ± 0.025	0.938CysIle: 0.938 ± 0.041	0.584CysLys: 0.584 ± 0.033	1.294CysLeu: 1.294 ± 0.05	0.342CysMet: 0.342 ± 0.022	0.433CysAsn: 0.433 ± 0.025	0.651CysPro: 0.651 ± 0.038	0.497CysGln: 0.497 ± 0.027	0.835CysArg: 0.835 ± 0.037	0.759CysSer: 0.759 ± 0.033	0.493CysThr: 0.493 ± 0.028	0.764CysVal: 0.764 ± 0.038	0.103CysTrp: 0.103 ± 0.014	0.442CysTyr: 0.442 ± 0.027	0.0CysXaa: 0.0 ± 0.0
Asp	4.682AspAla: 4.682 ± 0.094	0.81AspCys: 0.81 ± 0.045	2.961AspAsp: 2.961 ± 0.077	4.075AspGlu: 4.075 ± 0.096	2.912AspPhe: 2.912 ± 0.069	4.452AspGly: 4.452 ± 0.108	1.332AspHis: 1.332 ± 0.048	3.972AspIle: 3.972 ± 0.095	3.266AspLys: 3.266 ± 0.094	6.138AspLeu: 6.138 ± 0.102	1.8AspMet: 1.8 ± 0.048	1.813AspAsn: 1.813 ± 0.07	2.529AspPro: 2.529 ± 0.066	2.809AspGln: 2.809 ± 0.079	4.138AspArg: 4.138 ± 0.089	3.316AspSer: 3.316 ± 0.067	2.493AspThr: 2.493 ± 0.066	3.411AspVal: 3.411 ± 0.08	0.656AspTrp: 0.656 ± 0.04	2.707AspTyr: 2.707 ± 0.069	0.0AspXaa: 0.0 ± 0.0
Glu	5.995GluAla: 5.995 ± 0.106	0.536GluCys: 0.536 ± 0.036	4.766GluAsp: 4.766 ± 0.1	7.246GluGlu: 7.246 ± 0.139	1.994GluPhe: 1.994 ± 0.058	4.849GluGly: 4.849 ± 0.099	1.338GluHis: 1.338 ± 0.052	5.415GluIle: 5.415 ± 0.102	5.441GluLys: 5.441 ± 0.116	5.998GluLeu: 5.998 ± 0.125	2.153GluMet: 2.153 ± 0.055	3.382GluAsn: 3.382 ± 0.081	1.685GluPro: 1.685 ± 0.054	2.456GluGln: 2.456 ± 0.072	3.872GluArg: 3.872 ± 0.092	3.477GluSer: 3.477 ± 0.085	3.288GluThr: 3.288 ± 0.078	3.801GluVal: 3.801 ± 0.082	0.445GluTrp: 0.445 ± 0.027	2.302GluTyr: 2.302 ± 0.066	0.0GluXaa: 0.0 ± 0.0
Phe	3.448PheAla: 3.448 ± 0.075	0.682PheCys: 0.682 ± 0.033	2.678PheAsp: 2.678 ± 0.068	2.205PheGlu: 2.205 ± 0.049	1.942PhePhe: 1.942 ± 0.066	2.986PheGly: 2.986 ± 0.075	0.956PheHis: 0.956 ± 0.042	2.462PheIle: 2.462 ± 0.076	1.606PheLys: 1.606 ± 0.055	4.141PheLeu: 4.141 ± 0.101	1.132PheMet: 1.132 ± 0.04	1.295PheAsn: 1.295 ± 0.049	1.486PhePro: 1.486 ± 0.049	1.27PheGln: 1.27 ± 0.049	2.014PheArg: 2.014 ± 0.055	2.974PheSer: 2.974 ± 0.064	2.068PheThr: 2.068 ± 0.065	2.573PheVal: 2.573 ± 0.061	0.413PheTrp: 0.413 ± 0.023	1.706PheTyr: 1.706 ± 0.054	0.0PheXaa: 0.0 ± 0.0
Gly	5.57GlyAla: 5.57 ± 0.113	0.996GlyCys: 0.996 ± 0.043	3.984GlyAsp: 3.984 ± 0.077	4.472GlyGlu: 4.472 ± 0.098	3.06GlyPhe: 3.06 ± 0.072	5.35GlyGly: 5.35 ± 0.11	1.545GlyHis: 1.545 ± 0.051	5.878GlyIle: 5.878 ± 0.115	5.325GlyLys: 5.325 ± 0.101	6.836GlyLeu: 6.836 ± 0.118	2.466GlyMet: 2.466 ± 0.057	2.887GlyAsn: 2.887 ± 0.071	1.809GlyPro: 1.809 ± 0.056	3.377GlyGln: 3.377 ± 0.083	4.62GlyArg: 4.62 ± 0.104	4.64GlySer: 4.64 ± 0.094	3.553GlyThr: 3.553 ± 0.092	4.532GlyVal: 4.532 ± 0.102	0.698GlyTrp: 0.698 ± 0.034	2.974GlyTyr: 2.974 ± 0.08	0.0GlyXaa: 0.0 ± 0.0
His	1.258HisAla: 1.258 ± 0.044	0.296HisCys: 0.296 ± 0.022	0.942HisAsp: 0.942 ± 0.038	1.11HisGlu: 1.11 ± 0.047	1.07HisPhe: 1.07 ± 0.037	1.383HisGly: 1.383 ± 0.052	0.393HisHis: 0.393 ± 0.032	1.349HisIle: 1.349 ± 0.04	0.913HisLys: 0.913 ± 0.035	1.853HisLeu: 1.853 ± 0.056	0.581HisMet: 0.581 ± 0.029	0.701HisAsn: 0.701 ± 0.04	1.063HisPro: 1.063 ± 0.042	0.634HisGln: 0.634 ± 0.029	1.214HisArg: 1.214 ± 0.043	1.123HisSer: 1.123 ± 0.042	0.879HisThr: 0.879 ± 0.033	1.223HisVal: 1.223 ± 0.051	0.197HisTrp: 0.197 ± 0.02	0.824HisTyr: 0.824 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.054IleAla: 6.054 ± 0.118	1.214IleCys: 1.214 ± 0.044	4.133IleAsp: 4.133 ± 0.089	4.19IleGlu: 4.19 ± 0.086	2.926IlePhe: 2.926 ± 0.081	4.911IleGly: 4.911 ± 0.104	1.466IleHis: 1.466 ± 0.049	4.036IleIle: 4.036 ± 0.101	3.331IleLys: 3.331 ± 0.087	6.924IleLeu: 6.924 ± 0.13	1.765IleMet: 1.765 ± 0.056	2.393IleAsn: 2.393 ± 0.064	3.28IlePro: 3.28 ± 0.079	2.025IleGln: 2.025 ± 0.053	4.645IleArg: 4.645 ± 0.108	4.922IleSer: 4.922 ± 0.098	3.123IleThr: 3.123 ± 0.082	4.404IleVal: 4.404 ± 0.077	0.642IleTrp: 0.642 ± 0.035	2.555IleTyr: 2.555 ± 0.055	0.0IleXaa: 0.0 ± 0.0
Lys	4.759LysAla: 4.759 ± 0.105	0.459LysCys: 0.459 ± 0.027	3.451LysAsp: 3.451 ± 0.097	5.401LysGlu: 5.401 ± 0.127	1.554LysPhe: 1.554 ± 0.063	3.795LysGly: 3.795 ± 0.083	0.841LysHis: 0.841 ± 0.038	4.201LysIle: 4.201 ± 0.091	4.986LysLys: 4.986 ± 0.118	4.697LysLeu: 4.697 ± 0.093	1.883LysMet: 1.883 ± 0.055	2.713LysAsn: 2.713 ± 0.082	1.751LysPro: 1.751 ± 0.05	1.853LysGln: 1.853 ± 0.058	3.369LysArg: 3.369 ± 0.068	3.582LysSer: 3.582 ± 0.081	3.488LysThr: 3.488 ± 0.085	3.594LysVal: 3.594 ± 0.109	0.437LysTrp: 0.437 ± 0.026	2.191LysTyr: 2.191 ± 0.071	0.0LysXaa: 0.0 ± 0.0
Leu	8.575LeuAla: 8.575 ± 0.135	1.295LeuCys: 1.295 ± 0.045	5.418LeuAsp: 5.418 ± 0.096	5.832LeuGlu: 5.832 ± 0.106	3.724LeuPhe: 3.724 ± 0.082	6.471LeuGly: 6.471 ± 0.124	1.696LeuHis: 1.696 ± 0.055	6.354LeuIle: 6.354 ± 0.12	5.168LeuLys: 5.168 ± 0.093	9.551LeuLeu: 9.551 ± 0.196	2.72LeuMet: 2.72 ± 0.067	3.1LeuAsn: 3.1 ± 0.08	3.978LeuPro: 3.978 ± 0.084	2.747LeuGln: 2.747 ± 0.063	5.008LeuArg: 5.008 ± 0.108	6.697LeuSer: 6.697 ± 0.119	5.302LeuThr: 5.302 ± 0.078	6.086LeuVal: 6.086 ± 0.121	0.802LeuTrp: 0.802 ± 0.036	3.074LeuTyr: 3.074 ± 0.075	0.0LeuXaa: 0.0 ± 0.0
Met	2.598MetAla: 2.598 ± 0.07	0.317MetCys: 0.317 ± 0.025	2.022MetAsp: 2.022 ± 0.058	2.271MetGlu: 2.271 ± 0.069	0.804MetPhe: 0.804 ± 0.035	2.321MetGly: 2.321 ± 0.065	0.521MetHis: 0.521 ± 0.028	2.179MetIle: 2.179 ± 0.072	2.09MetLys: 2.09 ± 0.061	2.583MetLeu: 2.583 ± 0.066	0.912MetMet: 0.912 ± 0.044	1.337MetAsn: 1.337 ± 0.055	1.183MetPro: 1.183 ± 0.041	1.067MetGln: 1.067 ± 0.041	1.809MetArg: 1.809 ± 0.05	1.968MetSer: 1.968 ± 0.054	1.769MetThr: 1.769 ± 0.056	1.86MetVal: 1.86 ± 0.054	0.176MetTrp: 0.176 ± 0.016	0.728MetTyr: 0.728 ± 0.036	0.0MetXaa: 0.0 ± 0.0
Asn	3.072AsnAla: 3.072 ± 0.082	0.505AsnCys: 0.505 ± 0.033	1.789AsnAsp: 1.789 ± 0.07	2.165AsnGlu: 2.165 ± 0.074	1.492AsnPhe: 1.492 ± 0.052	2.8AsnGly: 2.8 ± 0.086	0.862AsnHis: 0.862 ± 0.042	2.544AsnIle: 2.544 ± 0.066	1.853AsnLys: 1.853 ± 0.069	3.408AsnLeu: 3.408 ± 0.078	1.192AsnMet: 1.192 ± 0.046	1.284AsnAsn: 1.284 ± 0.053	2.014AsnPro: 2.014 ± 0.072	1.508AsnGln: 1.508 ± 0.05	2.402AsnArg: 2.402 ± 0.059	2.019AsnSer: 2.019 ± 0.06	1.837AsnThr: 1.837 ± 0.064	2.33AsnVal: 2.33 ± 0.063	0.402AsnTrp: 0.402 ± 0.027	1.501AsnTyr: 1.501 ± 0.052	0.0AsnXaa: 0.0 ± 0.0
Pro	2.961ProAla: 2.961 ± 0.086	0.487ProCys: 0.487 ± 0.034	2.499ProAsp: 2.499 ± 0.06	2.783ProGlu: 2.783 ± 0.07	1.463ProPhe: 1.463 ± 0.05	2.875ProGly: 2.875 ± 0.069	0.645ProHis: 0.645 ± 0.033	2.181ProIle: 2.181 ± 0.064	1.896ProLys: 1.896 ± 0.065	3.234ProLeu: 3.234 ± 0.073	0.996ProMet: 0.996 ± 0.036	1.181ProAsn: 1.181 ± 0.04	0.821ProPro: 0.821 ± 0.037	1.283ProGln: 1.283 ± 0.045	1.665ProArg: 1.665 ± 0.057	2.111ProSer: 2.111 ± 0.057	1.612ProThr: 1.612 ± 0.066	2.921ProVal: 2.921 ± 0.08	0.348ProTrp: 0.348 ± 0.022	1.352ProTyr: 1.352 ± 0.044	0.0ProXaa: 0.0 ± 0.0
Gln	3.188GlnAla: 3.188 ± 0.087	0.268GlnCys: 0.268 ± 0.024	1.749GlnAsp: 1.749 ± 0.055	3.034GlnGlu: 3.034 ± 0.074	1.081GlnPhe: 1.081 ± 0.037	2.535GlnGly: 2.535 ± 0.058	0.459GlnHis: 0.459 ± 0.024	2.941GlnIle: 2.941 ± 0.073	2.676GlnLys: 2.676 ± 0.067	3.14GlnLeu: 3.14 ± 0.08	1.403GlnMet: 1.403 ± 0.044	1.346GlnAsn: 1.346 ± 0.048	0.918GlnPro: 0.918 ± 0.042	1.041GlnGln: 1.041 ± 0.049	1.78GlnArg: 1.78 ± 0.053	1.945GlnSer: 1.945 ± 0.065	1.985GlnThr: 1.985 ± 0.058	2.419GlnVal: 2.419 ± 0.071	0.306GlnTrp: 0.306 ± 0.026	1.126GlnTyr: 1.126 ± 0.046	0.0GlnXaa: 0.0 ± 0.0
Arg	4.397ArgAla: 4.397 ± 0.093	0.613ArgCys: 0.613 ± 0.032	3.664ArgAsp: 3.664 ± 0.079	5.524ArgGlu: 5.524 ± 0.106	2.219ArgPhe: 2.219 ± 0.058	4.047ArgGly: 4.047 ± 0.091	1.158ArgHis: 1.158 ± 0.044	4.218ArgIle: 4.218 ± 0.084	3.802ArgLys: 3.802 ± 0.081	5.342ArgLeu: 5.342 ± 0.111	2.034ArgMet: 2.034 ± 0.055	2.031ArgAsn: 2.031 ± 0.059	1.954ArgPro: 1.954 ± 0.057	2.689ArgGln: 2.689 ± 0.071	4.281ArgArg: 4.281 ± 0.122	3.095ArgSer: 3.095 ± 0.079	2.418ArgThr: 2.418 ± 0.065	3.653ArgVal: 3.653 ± 0.075	0.445ArgTrp: 0.445 ± 0.026	2.071ArgTyr: 2.071 ± 0.066	0.0ArgXaa: 0.0 ± 0.0
Ser	5.079SerAla: 5.079 ± 0.097	0.915SerCys: 0.915 ± 0.041	3.807SerAsp: 3.807 ± 0.098	3.657SerGlu: 3.657 ± 0.072	2.904SerPhe: 2.904 ± 0.076	5.29SerGly: 5.29 ± 0.119	1.184SerHis: 1.184 ± 0.041	3.872SerIle: 3.872 ± 0.071	3.246SerLys: 3.246 ± 0.086	6.046SerLeu: 6.046 ± 0.108	1.968SerMet: 1.968 ± 0.058	2.054SerAsn: 2.054 ± 0.063	2.117SerPro: 2.117 ± 0.066	2.227SerGln: 2.227 ± 0.069	3.719SerArg: 3.719 ± 0.078	3.972SerSer: 3.972 ± 0.107	2.495SerThr: 2.495 ± 0.067	4.19SerVal: 4.19 ± 0.1	0.633SerTrp: 0.633 ± 0.034	2.778SerTyr: 2.778 ± 0.075	0.0SerXaa: 0.0 ± 0.0
Thr	4.15ThrAla: 4.15 ± 0.088	0.576ThrCys: 0.576 ± 0.029	3.165ThrAsp: 3.165 ± 0.075	3.205ThrGlu: 3.205 ± 0.082	1.942ThrPhe: 1.942 ± 0.06	4.483ThrGly: 4.483 ± 0.095	0.79ThrHis: 0.79 ± 0.043	3.296ThrIle: 3.296 ± 0.077	2.276ThrLys: 2.276 ± 0.077	4.313ThrLeu: 4.313 ± 0.082	1.364ThrMet: 1.364 ± 0.05	1.702ThrAsn: 1.702 ± 0.067	1.97ThrPro: 1.97 ± 0.069	1.378ThrGln: 1.378 ± 0.046	2.526ThrArg: 2.526 ± 0.057	3.018ThrSer: 3.018 ± 0.068	2.182ThrThr: 2.182 ± 0.091	3.721ThrVal: 3.721 ± 0.1	0.437ThrTrp: 0.437 ± 0.033	1.746ThrTyr: 1.746 ± 0.058	0.0ThrXaa: 0.0 ± 0.0
Val	4.843ValAla: 4.843 ± 0.091	1.049ValCys: 1.049 ± 0.039	3.856ValAsp: 3.856 ± 0.092	4.064ValGlu: 4.064 ± 0.082	2.837ValPhe: 2.837 ± 0.072	4.249ValGly: 4.249 ± 0.097	1.072ValHis: 1.072 ± 0.046	4.86ValIle: 4.86 ± 0.101	3.665ValLys: 3.665 ± 0.084	5.873ValLeu: 5.873 ± 0.102	1.84ValMet: 1.84 ± 0.056	2.676ValAsn: 2.676 ± 0.097	2.201ValPro: 2.201 ± 0.068	1.725ValGln: 1.725 ± 0.049	3.751ValArg: 3.751 ± 0.078	4.825ValSer: 4.825 ± 0.093	3.836ValThr: 3.836 ± 0.093	3.831ValVal: 3.831 ± 0.095	0.564ValTrp: 0.564 ± 0.029	2.325ValTyr: 2.325 ± 0.061	0.0ValXaa: 0.0 ± 0.0
Trp	0.554TrpAla: 0.554 ± 0.033	0.142TrpCys: 0.142 ± 0.017	0.513TrpAsp: 0.513 ± 0.028	0.628TrpGlu: 0.628 ± 0.031	0.36TrpPhe: 0.36 ± 0.024	0.641TrpGly: 0.641 ± 0.029	0.183TrpHis: 0.183 ± 0.017	0.698TrpIle: 0.698 ± 0.033	0.642TrpLys: 0.642 ± 0.04	0.77TrpLeu: 0.77 ± 0.035	0.317TrpMet: 0.317 ± 0.024	0.419TrpAsn: 0.419 ± 0.029	0.254TrpPro: 0.254 ± 0.023	0.391TrpGln: 0.391 ± 0.024	0.447TrpArg: 0.447 ± 0.027	0.491TrpSer: 0.491 ± 0.03	0.484TrpThr: 0.484 ± 0.036	0.511TrpVal: 0.511 ± 0.031	0.1TrpTrp: 0.1 ± 0.011	0.297TrpTyr: 0.297 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.83TyrAla: 2.83 ± 0.066	0.479TyrCys: 0.479 ± 0.027	2.335TyrAsp: 2.335 ± 0.07	2.601TyrGlu: 2.601 ± 0.064	1.649TyrPhe: 1.649 ± 0.056	2.823TyrGly: 2.823 ± 0.07	0.855TyrHis: 0.855 ± 0.038	2.258TyrIle: 2.258 ± 0.061	1.66TyrLys: 1.66 ± 0.063	3.654TyrLeu: 3.654 ± 0.08	0.979TyrMet: 0.979 ± 0.039	1.297TyrAsn: 1.297 ± 0.047	1.472TyrPro: 1.472 ± 0.049	1.749TyrGln: 1.749 ± 0.056	2.529TyrArg: 2.529 ± 0.067	2.099TyrSer: 2.099 ± 0.061	1.8TyrThr: 1.8 ± 0.079	2.198TyrVal: 2.198 ± 0.06	0.356TyrTrp: 0.356 ± 0.021	1.441TyrTyr: 1.441 ± 0.056	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2247 proteins (649359 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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