Amino acid dipepetide frequency for Austwickia chelonae NBRC 105200

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.416AlaAla: 17.416 ± 0.208	1.199AlaCys: 1.199 ± 0.036	7.044AlaAsp: 7.044 ± 0.091	7.468AlaGlu: 7.468 ± 0.098	3.428AlaPhe: 3.428 ± 0.06	11.542AlaGly: 11.542 ± 0.138	2.702AlaHis: 2.702 ± 0.058	4.06AlaIle: 4.06 ± 0.081	2.957AlaLys: 2.957 ± 0.077	12.853AlaLeu: 12.853 ± 0.146	2.684AlaMet: 2.684 ± 0.052	1.923AlaAsn: 1.923 ± 0.047	6.222AlaPro: 6.222 ± 0.103	4.14AlaGln: 4.14 ± 0.067	8.969AlaArg: 8.969 ± 0.108	6.215AlaSer: 6.215 ± 0.09	6.896AlaThr: 6.896 ± 0.08	11.504AlaVal: 11.504 ± 0.127	1.673AlaTrp: 1.673 ± 0.041	2.395AlaTyr: 2.395 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.156CysAla: 1.156 ± 0.034	0.142CysCys: 0.142 ± 0.012	0.531CysAsp: 0.531 ± 0.024	0.45CysGlu: 0.45 ± 0.024	0.272CysPhe: 0.272 ± 0.017	1.112CysGly: 1.112 ± 0.035	0.212CysHis: 0.212 ± 0.016	0.277CysIle: 0.277 ± 0.018	0.118CysLys: 0.118 ± 0.013	0.995CysLeu: 0.995 ± 0.03	0.143CysMet: 0.143 ± 0.011	0.159CysAsn: 0.159 ± 0.013	0.609CysPro: 0.609 ± 0.027	0.221CysGln: 0.221 ± 0.015	0.686CysArg: 0.686 ± 0.024	0.571CysSer: 0.571 ± 0.022	0.572CysThr: 0.572 ± 0.027	0.695CysVal: 0.695 ± 0.026	0.119CysTrp: 0.119 ± 0.011	0.166CysTyr: 0.166 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.466AspAla: 6.466 ± 0.082	0.4AspCys: 0.4 ± 0.019	3.633AspAsp: 3.633 ± 0.071	3.989AspGlu: 3.989 ± 0.062	1.501AspPhe: 1.501 ± 0.047	5.589AspGly: 5.589 ± 0.084	1.44AspHis: 1.44 ± 0.043	2.462AspIle: 2.462 ± 0.049	1.326AspLys: 1.326 ± 0.047	6.568AspLeu: 6.568 ± 0.1	1.009AspMet: 1.009 ± 0.031	0.904AspAsn: 0.904 ± 0.036	4.308AspPro: 4.308 ± 0.077	1.702AspGln: 1.702 ± 0.044	4.633AspArg: 4.633 ± 0.071	2.636AspSer: 2.636 ± 0.051	2.887AspThr: 2.887 ± 0.064	5.024AspVal: 5.024 ± 0.071	0.753AspTrp: 0.753 ± 0.028	1.152AspTyr: 1.152 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	6.461GluAla: 6.461 ± 0.094	0.464GluCys: 0.464 ± 0.02	2.972GluAsp: 2.972 ± 0.062	3.822GluGlu: 3.822 ± 0.081	1.424GluPhe: 1.424 ± 0.033	4.288GluGly: 4.288 ± 0.068	1.507GluHis: 1.507 ± 0.042	2.835GluIle: 2.835 ± 0.053	1.883GluLys: 1.883 ± 0.056	5.918GluLeu: 5.918 ± 0.097	1.12GluMet: 1.12 ± 0.031	1.282GluAsn: 1.282 ± 0.033	2.745GluPro: 2.745 ± 0.064	2.342GluGln: 2.342 ± 0.05	4.685GluArg: 4.685 ± 0.074	2.957GluSer: 2.957 ± 0.056	2.81GluThr: 2.81 ± 0.047	4.528GluVal: 4.528 ± 0.066	0.686GluTrp: 0.686 ± 0.029	1.021GluTyr: 1.021 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.533PheAla: 3.533 ± 0.067	0.317PheCys: 0.317 ± 0.02	1.826PheAsp: 1.826 ± 0.045	1.369PheGlu: 1.369 ± 0.033	1.071PhePhe: 1.071 ± 0.039	2.936PheGly: 2.936 ± 0.056	0.584PheHis: 0.584 ± 0.024	0.949PheIle: 0.949 ± 0.034	0.484PheLys: 0.484 ± 0.021	2.796PheLeu: 2.796 ± 0.06	0.521PheMet: 0.521 ± 0.024	0.598PheAsn: 0.598 ± 0.023	1.484PhePro: 1.484 ± 0.035	0.627PheGln: 0.627 ± 0.026	1.62PheArg: 1.62 ± 0.036	1.724PheSer: 1.724 ± 0.039	1.967PheThr: 1.967 ± 0.045	2.719PheVal: 2.719 ± 0.054	0.421PheTrp: 0.421 ± 0.025	0.599PheTyr: 0.599 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	10.037GlyAla: 10.037 ± 0.106	0.965GlyCys: 0.965 ± 0.035	4.725GlyAsp: 4.725 ± 0.064	5.036GlyGlu: 5.036 ± 0.072	2.766GlyPhe: 2.766 ± 0.05	7.941GlyGly: 7.941 ± 0.121	2.344GlyHis: 2.344 ± 0.049	4.058GlyIle: 4.058 ± 0.074	2.674GlyLys: 2.674 ± 0.065	9.01GlyLeu: 9.01 ± 0.111	2.34GlyMet: 2.34 ± 0.049	1.75GlyAsn: 1.75 ± 0.049	4.59GlyPro: 4.59 ± 0.074	3.101GlyGln: 3.101 ± 0.066	7.471GlyArg: 7.471 ± 0.102	5.486GlySer: 5.486 ± 0.075	5.254GlyThr: 5.254 ± 0.073	8.026GlyVal: 8.026 ± 0.109	1.6GlyTrp: 1.6 ± 0.044	2.157GlyTyr: 2.157 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.388HisAla: 2.388 ± 0.054	0.227HisCys: 0.227 ± 0.015	1.572HisAsp: 1.572 ± 0.037	1.274HisGlu: 1.274 ± 0.037	0.642HisPhe: 0.642 ± 0.028	2.195HisGly: 2.195 ± 0.055	0.738HisHis: 0.738 ± 0.031	0.799HisIle: 0.799 ± 0.03	0.318HisLys: 0.318 ± 0.016	2.535HisLeu: 2.535 ± 0.051	0.348HisMet: 0.348 ± 0.019	0.35HisAsn: 0.35 ± 0.018	1.83HisPro: 1.83 ± 0.05	0.71HisGln: 0.71 ± 0.028	2.129HisArg: 2.129 ± 0.05	1.027HisSer: 1.027 ± 0.033	1.296HisThr: 1.296 ± 0.039	1.728HisVal: 1.728 ± 0.042	0.312HisTrp: 0.312 ± 0.017	0.429HisTyr: 0.429 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.279IleAla: 5.279 ± 0.071	0.427IleCys: 0.427 ± 0.021	2.81IleAsp: 2.81 ± 0.053	2.095IleGlu: 2.095 ± 0.047	1.153IlePhe: 1.153 ± 0.037	4.235IleGly: 4.235 ± 0.059	0.784IleHis: 0.784 ± 0.029	1.38IleIle: 1.38 ± 0.044	0.768IleLys: 0.768 ± 0.03	3.323IleLeu: 3.323 ± 0.065	0.686IleMet: 0.686 ± 0.025	0.854IleAsn: 0.854 ± 0.029	2.357IlePro: 2.357 ± 0.049	0.865IleGln: 0.865 ± 0.031	2.584IleArg: 2.584 ± 0.05	2.461IleSer: 2.461 ± 0.055	2.642IleThr: 2.642 ± 0.053	3.766IleVal: 3.766 ± 0.066	0.507IleTrp: 0.507 ± 0.022	0.737IleTyr: 0.737 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.932LysAla: 2.932 ± 0.073	0.128LysCys: 0.128 ± 0.011	1.498LysAsp: 1.498 ± 0.046	1.363LysGlu: 1.363 ± 0.045	0.452LysPhe: 0.452 ± 0.022	1.849LysGly: 1.849 ± 0.052	0.43LysHis: 0.43 ± 0.024	1.156LysIle: 1.156 ± 0.038	1.095LysLys: 1.095 ± 0.044	1.939LysLeu: 1.939 ± 0.048	0.536LysMet: 0.536 ± 0.024	0.725LysAsn: 0.725 ± 0.033	1.35LysPro: 1.35 ± 0.052	0.768LysGln: 0.768 ± 0.031	1.349LysArg: 1.349 ± 0.04	1.378LysSer: 1.378 ± 0.04	1.446LysThr: 1.446 ± 0.046	2.297LysVal: 2.297 ± 0.057	0.223LysTrp: 0.223 ± 0.016	0.526LysTyr: 0.526 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	13.746LeuAla: 13.746 ± 0.15	0.942LeuCys: 0.942 ± 0.027	6.112LeuAsp: 6.112 ± 0.095	4.333LeuGlu: 4.333 ± 0.075	2.757LeuPhe: 2.757 ± 0.065	8.905LeuGly: 8.905 ± 0.106	2.101LeuHis: 2.101 ± 0.051	3.9LeuIle: 3.9 ± 0.068	1.887LeuLys: 1.887 ± 0.051	10.307LeuLeu: 10.307 ± 0.148	1.934LeuMet: 1.934 ± 0.045	1.831LeuAsn: 1.831 ± 0.037	6.134LeuPro: 6.134 ± 0.094	2.425LeuGln: 2.425 ± 0.049	7.401LeuArg: 7.401 ± 0.1	6.458LeuSer: 6.458 ± 0.085	6.682LeuThr: 6.682 ± 0.083	9.227LeuVal: 9.227 ± 0.112	1.288LeuTrp: 1.288 ± 0.036	1.569LeuTyr: 1.569 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	2.486MetAla: 2.486 ± 0.051	0.182MetCys: 0.182 ± 0.014	0.948MetAsp: 0.948 ± 0.034	0.798MetGlu: 0.798 ± 0.03	0.536MetPhe: 0.536 ± 0.023	1.579MetGly: 1.579 ± 0.045	0.442MetHis: 0.442 ± 0.023	0.999MetIle: 0.999 ± 0.03	0.621MetLys: 0.621 ± 0.029	1.96MetLeu: 1.96 ± 0.049	0.477MetMet: 0.477 ± 0.023	0.59MetAsn: 0.59 ± 0.023	1.274MetPro: 1.274 ± 0.035	0.576MetGln: 0.576 ± 0.023	1.509MetArg: 1.509 ± 0.036	1.84MetSer: 1.84 ± 0.041	1.917MetThr: 1.917 ± 0.042	1.785MetVal: 1.785 ± 0.044	0.243MetTrp: 0.243 ± 0.016	0.341MetTyr: 0.341 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.159AsnAla: 2.159 ± 0.052	0.187AsnCys: 0.187 ± 0.014	1.035AsnAsp: 1.035 ± 0.032	0.845AsnGlu: 0.845 ± 0.034	0.541AsnPhe: 0.541 ± 0.025	1.744AsnGly: 1.744 ± 0.045	0.401AsnHis: 0.401 ± 0.019	0.823AsnIle: 0.823 ± 0.026	0.465AsnLys: 0.465 ± 0.024	1.841AsnLeu: 1.841 ± 0.042	0.354AsnMet: 0.354 ± 0.019	0.479AsnAsn: 0.479 ± 0.024	1.554AsnPro: 1.554 ± 0.038	0.58AsnGln: 0.58 ± 0.022	1.313AsnArg: 1.313 ± 0.041	1.105AsnSer: 1.105 ± 0.04	1.197AsnThr: 1.197 ± 0.036	1.472AsnVal: 1.472 ± 0.04	0.266AsnTrp: 0.266 ± 0.015	0.447AsnTyr: 0.447 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	7.155ProAla: 7.155 ± 0.117	0.35ProCys: 0.35 ± 0.021	3.85ProAsp: 3.85 ± 0.07	4.075ProGlu: 4.075 ± 0.082	1.533ProPhe: 1.533 ± 0.037	6.257ProGly: 6.257 ± 0.103	1.287ProHis: 1.287 ± 0.039	1.693ProIle: 1.693 ± 0.041	1.236ProLys: 1.236 ± 0.041	4.95ProLeu: 4.95 ± 0.081	1.161ProMet: 1.161 ± 0.033	0.917ProAsn: 0.917 ± 0.032	3.167ProPro: 3.167 ± 0.085	1.937ProGln: 1.937 ± 0.048	3.825ProArg: 3.825 ± 0.074	3.53ProSer: 3.53 ± 0.075	3.786ProThr: 3.786 ± 0.072	5.46ProVal: 5.46 ± 0.083	0.922ProTrp: 0.922 ± 0.033	1.175ProTyr: 1.175 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.015GlnAla: 4.015 ± 0.082	0.196GlnCys: 0.196 ± 0.014	1.701GlnAsp: 1.701 ± 0.042	1.826GlnGlu: 1.826 ± 0.042	0.668GlnPhe: 0.668 ± 0.024	2.543GlnGly: 2.543 ± 0.052	0.601GlnHis: 0.601 ± 0.025	1.722GlnIle: 1.722 ± 0.035	0.766GlnLys: 0.766 ± 0.032	2.88GlnLeu: 2.88 ± 0.054	0.7GlnMet: 0.7 ± 0.026	0.608GlnAsn: 0.608 ± 0.026	1.483GlnPro: 1.483 ± 0.049	1.054GlnGln: 1.054 ± 0.034	2.257GlnArg: 2.257 ± 0.048	1.443GlnSer: 1.443 ± 0.043	1.499GlnThr: 1.499 ± 0.038	3.181GlnVal: 3.181 ± 0.062	0.437GlnTrp: 0.437 ± 0.025	0.538GlnTyr: 0.538 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	8.469ArgAla: 8.469 ± 0.114	0.691ArgCys: 0.691 ± 0.03	3.749ArgAsp: 3.749 ± 0.064	4.318ArgGlu: 4.318 ± 0.066	2.073ArgPhe: 2.073 ± 0.04	5.478ArgGly: 5.478 ± 0.077	2.101ArgHis: 2.101 ± 0.054	3.579ArgIle: 3.579 ± 0.063	1.603ArgLys: 1.603 ± 0.042	7.556ArgLeu: 7.556 ± 0.104	2.007ArgMet: 2.007 ± 0.039	1.28ArgAsn: 1.28 ± 0.038	4.64ArgPro: 4.64 ± 0.082	2.432ArgGln: 2.432 ± 0.049	7.386ArgArg: 7.386 ± 0.12	4.327ArgSer: 4.327 ± 0.07	4.668ArgThr: 4.668 ± 0.067	5.791ArgVal: 5.791 ± 0.083	1.323ArgTrp: 1.323 ± 0.041	1.642ArgTyr: 1.642 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	7.209SerAla: 7.209 ± 0.106	0.567SerCys: 0.567 ± 0.025	2.821SerAsp: 2.821 ± 0.053	2.674SerGlu: 2.674 ± 0.052	1.877SerPhe: 1.877 ± 0.045	6.247SerGly: 6.247 ± 0.086	1.137SerHis: 1.137 ± 0.031	2.007SerIle: 2.007 ± 0.041	1.139SerLys: 1.139 ± 0.034	5.411SerLeu: 5.411 ± 0.072	1.385SerMet: 1.385 ± 0.035	0.953SerAsn: 0.953 ± 0.033	3.608SerPro: 3.608 ± 0.077	1.579SerGln: 1.579 ± 0.052	4.224SerArg: 4.224 ± 0.067	4.046SerSer: 4.046 ± 0.071	3.873SerThr: 3.873 ± 0.069	4.699SerVal: 4.699 ± 0.079	1.153SerTrp: 1.153 ± 0.036	1.303SerTyr: 1.303 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	7.475ThrAla: 7.475 ± 0.105	0.582ThrCys: 0.582 ± 0.029	3.481ThrAsp: 3.481 ± 0.059	2.913ThrGlu: 2.913 ± 0.063	1.825ThrPhe: 1.825 ± 0.041	6.184ThrGly: 6.184 ± 0.09	1.295ThrHis: 1.295 ± 0.031	2.188ThrIle: 2.188 ± 0.041	1.371ThrLys: 1.371 ± 0.039	5.702ThrLeu: 5.702 ± 0.103	1.236ThrMet: 1.236 ± 0.035	1.094ThrAsn: 1.094 ± 0.038	4.167ThrPro: 4.167 ± 0.086	1.611ThrGln: 1.611 ± 0.041	4.027ThrArg: 4.027 ± 0.062	3.64ThrSer: 3.64 ± 0.067	4.24ThrThr: 4.24 ± 0.09	6.083ThrVal: 6.083 ± 0.096	0.99ThrTrp: 0.99 ± 0.037	1.414ThrTyr: 1.414 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	10.893ValAla: 10.893 ± 0.118	0.891ValCys: 0.891 ± 0.029	6.043ValAsp: 6.043 ± 0.086	5.326ValGlu: 5.326 ± 0.077	2.543ValPhe: 2.543 ± 0.05	7.582ValGly: 7.582 ± 0.105	1.981ValHis: 1.981 ± 0.047	3.684ValIle: 3.684 ± 0.066	1.987ValLys: 1.987 ± 0.056	9.503ValLeu: 9.503 ± 0.129	1.823ValMet: 1.823 ± 0.047	1.785ValAsn: 1.785 ± 0.043	4.984ValPro: 4.984 ± 0.078	2.22ValGln: 2.22 ± 0.048	6.211ValArg: 6.211 ± 0.076	5.078ValSer: 5.078 ± 0.072	5.803ValThr: 5.803 ± 0.084	9.83ValVal: 9.83 ± 0.125	1.016ValTrp: 1.016 ± 0.035	1.489ValTyr: 1.489 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.614TrpAla: 1.614 ± 0.04	0.173TrpCys: 0.173 ± 0.014	0.669TrpAsp: 0.669 ± 0.025	0.682TrpGlu: 0.682 ± 0.025	0.481TrpPhe: 0.481 ± 0.023	1.069TrpGly: 1.069 ± 0.032	0.351TrpHis: 0.351 ± 0.022	0.567TrpIle: 0.567 ± 0.025	0.375TrpLys: 0.375 ± 0.02	1.577TrpLeu: 1.577 ± 0.038	0.364TrpMet: 0.364 ± 0.022	0.363TrpAsn: 0.363 ± 0.02	0.746TrpPro: 0.746 ± 0.03	0.623TrpGln: 0.623 ± 0.023	1.17TrpArg: 1.17 ± 0.036	1.007TrpSer: 1.007 ± 0.031	0.949TrpThr: 0.949 ± 0.032	1.15TrpVal: 1.15 ± 0.033	0.418TrpTrp: 0.418 ± 0.019	0.298TrpTyr: 0.298 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.4TyrAla: 2.4 ± 0.045	0.178TyrCys: 0.178 ± 0.013	1.362TyrAsp: 1.362 ± 0.044	1.095TyrGlu: 1.095 ± 0.032	0.604TyrPhe: 0.604 ± 0.026	2.055TyrGly: 2.055 ± 0.051	0.408TyrHis: 0.408 ± 0.021	0.573TyrIle: 0.573 ± 0.025	0.366TyrLys: 0.366 ± 0.021	2.316TyrLeu: 2.316 ± 0.047	0.274TyrMet: 0.274 ± 0.017	0.365TyrAsn: 0.365 ± 0.022	1.015TyrPro: 1.015 ± 0.032	0.606TyrGln: 0.606 ± 0.023	1.667TyrArg: 1.667 ± 0.039	0.98TyrSer: 0.98 ± 0.035	1.132TyrThr: 1.132 ± 0.035	1.705TyrVal: 1.705 ± 0.044	0.295TyrTrp: 0.295 ± 0.017	0.412TyrTyr: 0.412 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3048 proteins (1038619 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---