Amino acid dipepetide frequency for Tortoise microvirus 96

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.432AlaAla: 7.432 ± 3.102
0.0AlaCys: 0.0 ± 0.0
1.351AlaAsp: 1.351 ± 0.645
4.054AlaGlu: 4.054 ± 1.149
3.378AlaPhe: 3.378 ± 0.857
5.405AlaGly: 5.405 ± 1.419
0.0AlaHis: 0.0 ± 0.0
3.378AlaIle: 3.378 ± 1.128
3.378AlaLys: 3.378 ± 1.857
2.703AlaLeu: 2.703 ± 0.99
2.027AlaMet: 2.027 ± 2.849
2.703AlaAsn: 2.703 ± 1.372
4.73AlaPro: 4.73 ± 2.75
4.054AlaGln: 4.054 ± 3.131
2.703AlaArg: 2.703 ± 0.99
6.081AlaSer: 6.081 ± 2.276
3.378AlaThr: 3.378 ± 1.08
4.054AlaVal: 4.054 ± 1.149
2.027AlaTrp: 2.027 ± 0.483
3.378AlaTyr: 3.378 ± 1.857
0.0AlaXaa: 0.0 ± 0.0
Cys
0.676CysAla: 0.676 ± 0.648
0.0CysCys: 0.0 ± 0.0
0.676CysAsp: 0.676 ± 0.482
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.676CysGly: 0.676 ± 0.648
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.676CysLys: 0.676 ± 0.648
1.351CysLeu: 1.351 ± 1.296
0.0CysMet: 0.0 ± 0.0
1.351CysAsn: 1.351 ± 1.296
0.676CysPro: 0.676 ± 1.004
0.676CysGln: 0.676 ± 0.482
1.351CysArg: 1.351 ± 0.569
0.676CysSer: 0.676 ± 0.943
0.0CysThr: 0.0 ± 0.0
2.027CysVal: 2.027 ± 1.944
0.0CysTrp: 0.0 ± 0.0
1.351CysTyr: 1.351 ± 1.096
0.0CysXaa: 0.0 ± 0.0
Asp
5.405AspAla: 5.405 ± 3.097
0.0AspCys: 0.0 ± 0.0
2.703AspAsp: 2.703 ± 1.774
6.081AspGlu: 6.081 ± 3.41
2.703AspPhe: 2.703 ± 1.389
2.703AspGly: 2.703 ± 1.282
1.351AspHis: 1.351 ± 0.569
4.054AspIle: 4.054 ± 0.738
0.676AspLys: 0.676 ± 0.648
8.108AspLeu: 8.108 ± 2.216
0.676AspMet: 0.676 ± 0.617
6.081AspAsn: 6.081 ± 2.211
0.676AspPro: 0.676 ± 1.004
0.0AspGln: 0.0 ± 0.0
1.351AspArg: 1.351 ± 0.645
4.73AspSer: 4.73 ± 2.647
2.703AspThr: 2.703 ± 0.845
4.054AspVal: 4.054 ± 1.588
0.0AspTrp: 0.0 ± 0.0
4.054AspTyr: 4.054 ± 1.662
0.0AspXaa: 0.0 ± 0.0
Glu
3.378GluAla: 3.378 ± 1.949
0.0GluCys: 0.0 ± 0.0
2.703GluAsp: 2.703 ± 1.774
1.351GluGlu: 1.351 ± 1.886
2.703GluPhe: 2.703 ± 1.138
0.676GluGly: 0.676 ± 0.617
0.676GluHis: 0.676 ± 0.482
2.027GluIle: 2.027 ± 1.015
4.054GluLys: 4.054 ± 1.382
6.081GluLeu: 6.081 ± 0.634
2.027GluMet: 2.027 ± 3.011
2.703GluAsn: 2.703 ± 0.8
2.027GluPro: 2.027 ± 1.832
1.351GluGln: 1.351 ± 0.645
0.0GluArg: 0.0 ± 0.0
2.027GluSer: 2.027 ± 0.483
1.351GluThr: 1.351 ± 0.963
2.027GluVal: 2.027 ± 0.958
0.0GluTrp: 0.0 ± 0.0
4.73GluTyr: 4.73 ± 1.492
0.0GluXaa: 0.0 ± 0.0
Phe
2.027PheAla: 2.027 ± 1.445
0.676PheCys: 0.676 ± 0.648
2.703PheAsp: 2.703 ± 1.356
4.054PheGlu: 4.054 ± 0.738
2.703PhePhe: 2.703 ± 1.927
4.73PheGly: 4.73 ± 1.347
0.676PheHis: 0.676 ± 0.648
3.378PheIle: 3.378 ± 0.657
4.73PheLys: 4.73 ± 2.049
4.054PheLeu: 4.054 ± 1.379
1.351PheMet: 1.351 ± 0.837
6.757PheAsn: 6.757 ± 1.504
1.351PhePro: 1.351 ± 0.569
1.351PheGln: 1.351 ± 0.963
3.378PheArg: 3.378 ± 1.655
1.351PheSer: 1.351 ± 0.963
4.054PheThr: 4.054 ± 1.807
4.054PheVal: 4.054 ± 1.379
2.027PheTrp: 2.027 ± 0.958
1.351PheTyr: 1.351 ± 0.569
0.0PheXaa: 0.0 ± 0.0
Gly
1.351GlyAla: 1.351 ± 0.645
0.676GlyCys: 0.676 ± 0.648
2.703GlyAsp: 2.703 ± 1.798
1.351GlyGlu: 1.351 ± 0.963
3.378GlyPhe: 3.378 ± 1.133
4.73GlyGly: 4.73 ± 2.609
0.0GlyHis: 0.0 ± 0.0
6.081GlyIle: 6.081 ± 2.06
3.378GlyLys: 3.378 ± 1.341
5.405GlyLeu: 5.405 ± 2.704
0.676GlyMet: 0.676 ± 0.617
4.054GlyAsn: 4.054 ± 0.808
0.676GlyPro: 0.676 ± 0.482
5.405GlyGln: 5.405 ± 1.336
4.054GlyArg: 4.054 ± 1.929
2.027GlySer: 2.027 ± 1.445
2.703GlyThr: 2.703 ± 1.282
6.081GlyVal: 6.081 ± 4.336
0.0GlyTrp: 0.0 ± 0.0
4.054GlyTyr: 4.054 ± 1.638
0.0GlyXaa: 0.0 ± 0.0
His
0.676HisAla: 0.676 ± 0.648
1.351HisCys: 1.351 ± 1.296
0.676HisAsp: 0.676 ± 0.943
0.676HisGlu: 0.676 ± 0.482
1.351HisPhe: 1.351 ± 0.963
1.351HisGly: 1.351 ± 0.861
0.0HisHis: 0.0 ± 0.0
1.351HisIle: 1.351 ± 0.861
0.676HisLys: 0.676 ± 0.648
2.027HisLeu: 2.027 ± 1.334
0.676HisMet: 0.676 ± 0.648
0.676HisAsn: 0.676 ± 0.482
0.676HisPro: 0.676 ± 1.004
1.351HisGln: 1.351 ± 0.569
2.027HisArg: 2.027 ± 1.028
2.027HisSer: 2.027 ± 1.535
0.676HisThr: 0.676 ± 0.482
0.0HisVal: 0.0 ± 0.0
0.676HisTrp: 0.676 ± 0.482
1.351HisTyr: 1.351 ± 0.569
0.0HisXaa: 0.0 ± 0.0
Ile
2.703IleAla: 2.703 ± 1.372
0.676IleCys: 0.676 ± 1.004
4.73IleAsp: 4.73 ± 1.824
0.0IleGlu: 0.0 ± 0.0
4.054IlePhe: 4.054 ± 1.464
2.027IleGly: 2.027 ± 0.852
0.0IleHis: 0.0 ± 0.0
2.703IleIle: 2.703 ± 1.288
2.703IleLys: 2.703 ± 2.114
4.054IleLeu: 4.054 ± 1.379
3.378IleMet: 3.378 ± 1.679
5.405IleAsn: 5.405 ± 0.68
2.703IlePro: 2.703 ± 0.845
2.703IleGln: 2.703 ± 0.637
4.054IleArg: 4.054 ± 1.527
4.054IleSer: 4.054 ± 1.521
3.378IleThr: 3.378 ± 0.938
2.027IleVal: 2.027 ± 1.94
0.676IleTrp: 0.676 ± 0.648
4.73IleTyr: 4.73 ± 1.187
0.0IleXaa: 0.0 ± 0.0
Lys
3.378LysAla: 3.378 ± 1.033
0.676LysCys: 0.676 ± 0.648
3.378LysAsp: 3.378 ± 1.642
0.676LysGlu: 0.676 ± 0.482
1.351LysPhe: 1.351 ± 0.963
2.703LysGly: 2.703 ± 0.943
2.027LysHis: 2.027 ± 1.74
2.027LysIle: 2.027 ± 0.483
0.676LysLys: 0.676 ± 0.482
3.378LysLeu: 3.378 ± 0.857
0.0LysMet: 0.0 ± 0.0
4.054LysAsn: 4.054 ± 1.379
1.351LysPro: 1.351 ± 1.296
4.054LysGln: 4.054 ± 2.032
4.054LysArg: 4.054 ± 2.173
2.703LysSer: 2.703 ± 0.95
2.703LysThr: 2.703 ± 1.138
2.027LysVal: 2.027 ± 1.445
0.676LysTrp: 0.676 ± 0.482
5.405LysTyr: 5.405 ± 1.269
0.0LysXaa: 0.0 ± 0.0
Leu
4.73LeuAla: 4.73 ± 1.536
1.351LeuCys: 1.351 ± 0.861
8.108LeuAsp: 8.108 ± 3.361
0.676LeuGlu: 0.676 ± 0.617
6.081LeuPhe: 6.081 ± 1.7
9.459LeuGly: 9.459 ± 4.132
1.351LeuHis: 1.351 ± 1.096
4.73LeuIle: 4.73 ± 1.644
6.757LeuLys: 6.757 ± 2.183
4.73LeuLeu: 4.73 ± 1.959
0.676LeuMet: 0.676 ± 0.482
4.73LeuAsn: 4.73 ± 2.49
4.054LeuPro: 4.054 ± 1.596
6.081LeuGln: 6.081 ± 2.161
6.757LeuArg: 6.757 ± 2.79
7.432LeuSer: 7.432 ± 1.776
3.378LeuThr: 3.378 ± 1.238
2.703LeuVal: 2.703 ± 0.637
1.351LeuTrp: 1.351 ± 0.725
2.703LeuTyr: 2.703 ± 1.372
0.0LeuXaa: 0.0 ± 0.0
Met
0.676MetAla: 0.676 ± 0.617
0.676MetCys: 0.676 ± 0.482
2.027MetAsp: 2.027 ± 1.334
2.703MetGlu: 2.703 ± 1.958
1.351MetPhe: 1.351 ± 1.161
0.676MetGly: 0.676 ± 0.617
0.676MetHis: 0.676 ± 0.482
0.676MetIle: 0.676 ± 0.648
0.676MetLys: 0.676 ± 0.482
2.703MetLeu: 2.703 ± 1.264
0.676MetMet: 0.676 ± 0.943
2.027MetAsn: 2.027 ± 1.179
2.703MetPro: 2.703 ± 1.318
0.676MetGln: 0.676 ± 0.482
2.027MetArg: 2.027 ± 0.878
3.378MetSer: 3.378 ± 1.685
0.0MetThr: 0.0 ± 0.0
1.351MetVal: 1.351 ± 0.963
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.703AsnAla: 2.703 ± 1.737
1.351AsnCys: 1.351 ± 1.096
5.405AsnAsp: 5.405 ± 0.767
3.378AsnGlu: 3.378 ± 1.092
5.405AsnPhe: 5.405 ± 1.888
2.703AsnGly: 2.703 ± 1.372
0.0AsnHis: 0.0 ± 0.0
1.351AsnIle: 1.351 ± 0.887
5.405AsnLys: 5.405 ± 2.673
10.811AsnLeu: 10.811 ± 2.074
2.027AsnMet: 2.027 ± 0.532
5.405AsnAsn: 5.405 ± 2.702
4.73AsnPro: 4.73 ± 1.492
2.703AsnGln: 2.703 ± 2.466
4.054AsnArg: 4.054 ± 1.258
4.054AsnSer: 4.054 ± 2.885
3.378AsnThr: 3.378 ± 0.657
2.027AsnVal: 2.027 ± 1.121
0.0AsnTrp: 0.0 ± 0.0
2.703AsnTyr: 2.703 ± 0.943
0.0AsnXaa: 0.0 ± 0.0
Pro
2.027ProAla: 2.027 ± 1.015
0.676ProCys: 0.676 ± 0.648
2.027ProAsp: 2.027 ± 1.334
1.351ProGlu: 1.351 ± 0.861
2.027ProPhe: 2.027 ± 1.445
0.676ProGly: 0.676 ± 1.004
0.676ProHis: 0.676 ± 0.648
6.757ProIle: 6.757 ± 1.552
2.703ProLys: 2.703 ± 1.234
4.73ProLeu: 4.73 ± 1.908
1.351ProMet: 1.351 ± 0.861
4.054ProAsn: 4.054 ± 1.149
0.676ProPro: 0.676 ± 0.943
2.703ProGln: 2.703 ± 0.99
2.703ProArg: 2.703 ± 1.138
2.703ProSer: 2.703 ± 1.927
3.378ProThr: 3.378 ± 0.601
4.054ProVal: 4.054 ± 1.155
1.351ProTrp: 1.351 ± 0.569
2.703ProTyr: 2.703 ± 1.356
0.0ProXaa: 0.0 ± 0.0
Gln
6.081GlnAla: 6.081 ± 4.246
0.0GlnCys: 0.0 ± 0.0
2.027GlnAsp: 2.027 ± 0.483
3.378GlnGlu: 3.378 ± 1.222
2.703GlnPhe: 2.703 ± 1.138
2.027GlnGly: 2.027 ± 0.832
2.027GlnHis: 2.027 ± 1.121
3.378GlnIle: 3.378 ± 1.3
2.703GlnLys: 2.703 ± 1.372
4.73GlnLeu: 4.73 ± 2.301
1.351GlnMet: 1.351 ± 1.233
3.378GlnAsn: 3.378 ± 3.083
3.378GlnPro: 3.378 ± 1.404
2.703GlnGln: 2.703 ± 0.99
2.027GlnArg: 2.027 ± 1.015
2.703GlnSer: 2.703 ± 1.356
2.027GlnThr: 2.027 ± 0.958
2.027GlnVal: 2.027 ± 0.966
0.676GlnTrp: 0.676 ± 0.482
2.703GlnTyr: 2.703 ± 0.943
0.0GlnXaa: 0.0 ± 0.0
Arg
4.73ArgAla: 4.73 ± 1.564
0.676ArgCys: 0.676 ± 0.648
2.027ArgAsp: 2.027 ± 1.121
3.378ArgGlu: 3.378 ± 1.128
2.703ArgPhe: 2.703 ± 0.8
2.703ArgGly: 2.703 ± 1.356
2.703ArgHis: 2.703 ± 1.282
4.054ArgIle: 4.054 ± 1.588
0.676ArgLys: 0.676 ± 0.648
5.405ArgLeu: 5.405 ± 0.987
1.351ArgMet: 1.351 ± 0.541
3.378ArgAsn: 3.378 ± 0.938
2.703ArgPro: 2.703 ± 0.845
2.703ArgGln: 2.703 ± 0.95
3.378ArgArg: 3.378 ± 1.093
5.405ArgSer: 5.405 ± 0.959
2.703ArgThr: 2.703 ± 1.927
2.027ArgVal: 2.027 ± 0.483
0.0ArgTrp: 0.0 ± 0.0
2.703ArgTyr: 2.703 ± 0.637
0.0ArgXaa: 0.0 ± 0.0
Ser
6.081SerAla: 6.081 ± 2.592
0.676SerCys: 0.676 ± 0.648
2.703SerAsp: 2.703 ± 1.798
2.027SerGlu: 2.027 ± 0.483
5.405SerPhe: 5.405 ± 0.767
7.432SerGly: 7.432 ± 0.957
2.027SerHis: 2.027 ± 1.015
5.405SerIle: 5.405 ± 2.604
2.703SerLys: 2.703 ± 0.943
4.73SerLeu: 4.73 ± 2.413
2.027SerMet: 2.027 ± 1.565
3.378SerAsn: 3.378 ± 1.146
5.405SerPro: 5.405 ± 0.767
4.73SerGln: 4.73 ± 2.244
4.054SerArg: 4.054 ± 1.915
6.757SerSer: 6.757 ± 1.638
2.703SerThr: 2.703 ± 1.372
4.73SerVal: 4.73 ± 3.633
0.0SerTrp: 0.0 ± 0.0
1.351SerTyr: 1.351 ± 0.569
0.0SerXaa: 0.0 ± 0.0
Thr
4.73ThrAla: 4.73 ± 1.283
0.0ThrCys: 0.0 ± 0.0
3.378ThrAsp: 3.378 ± 1.751
3.378ThrGlu: 3.378 ± 1.706
4.73ThrPhe: 4.73 ± 1.387
0.676ThrGly: 0.676 ± 0.482
2.027ThrHis: 2.027 ± 1.028
3.378ThrIle: 3.378 ± 1.279
0.676ThrLys: 0.676 ± 0.943
2.703ThrLeu: 2.703 ± 1.74
2.027ThrMet: 2.027 ± 0.964
1.351ThrAsn: 1.351 ± 0.569
2.703ThrPro: 2.703 ± 0.637
0.0ThrGln: 0.0 ± 0.0
1.351ThrArg: 1.351 ± 0.861
5.405ThrSer: 5.405 ± 2.089
4.054ThrThr: 4.054 ± 1.021
3.378ThrVal: 3.378 ± 1.679
0.676ThrTrp: 0.676 ± 0.648
2.027ThrTyr: 2.027 ± 1.229
0.0ThrXaa: 0.0 ± 0.0
Val
4.054ValAla: 4.054 ± 0.966
1.351ValCys: 1.351 ± 1.296
3.378ValAsp: 3.378 ± 1.679
2.027ValGlu: 2.027 ± 0.878
0.0ValPhe: 0.0 ± 0.0
4.054ValGly: 4.054 ± 0.934
1.351ValHis: 1.351 ± 1.096
0.676ValIle: 0.676 ± 0.648
3.378ValLys: 3.378 ± 1.021
4.054ValLeu: 4.054 ± 0.738
1.351ValMet: 1.351 ± 0.645
2.703ValAsn: 2.703 ± 1.138
6.081ValPro: 6.081 ± 2.688
4.73ValGln: 4.73 ± 1.861
2.703ValArg: 2.703 ± 1.234
4.73ValSer: 4.73 ± 1.187
3.378ValThr: 3.378 ± 2.702
5.405ValVal: 5.405 ± 2.023
0.0ValTrp: 0.0 ± 0.0
0.676ValTyr: 0.676 ± 0.943
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.676TrpAsp: 0.676 ± 0.617
0.676TrpGlu: 0.676 ± 0.482
0.0TrpPhe: 0.0 ± 0.0
0.676TrpGly: 0.676 ± 0.482
1.351TrpHis: 1.351 ± 0.569
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.676TrpLeu: 0.676 ± 0.648
0.0TrpMet: 0.0 ± 0.0
0.676TrpAsn: 0.676 ± 0.648
0.676TrpPro: 0.676 ± 0.482
2.027TrpGln: 2.027 ± 0.832
0.676TrpArg: 0.676 ± 0.617
1.351TrpSer: 1.351 ± 0.645
1.351TrpThr: 1.351 ± 0.569
0.676TrpVal: 0.676 ± 0.648
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.378TyrAla: 3.378 ± 2.409
1.351TyrCys: 1.351 ± 0.569
4.73TyrAsp: 4.73 ± 0.822
0.676TyrGlu: 0.676 ± 0.482
5.405TyrPhe: 5.405 ± 1.613
2.703TyrGly: 2.703 ± 0.8
1.351TyrHis: 1.351 ± 0.569
1.351TyrIle: 1.351 ± 0.569
0.676TyrLys: 0.676 ± 0.482
5.405TyrLeu: 5.405 ± 1.99
1.351TyrMet: 1.351 ± 0.963
4.73TyrAsn: 4.73 ± 1.84
1.351TyrPro: 1.351 ± 0.569
2.027TyrGln: 2.027 ± 1.179
2.703TyrArg: 2.703 ± 1.372
4.73TyrSer: 4.73 ± 1.657
1.351TyrThr: 1.351 ± 0.963
1.351TyrVal: 1.351 ± 0.569
1.351TyrTrp: 1.351 ± 0.569
3.378TyrTyr: 3.378 ± 1.545
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1481 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski