Amino acid dipepetide frequency for Dengue virus type 1 (strain Nauru/West Pac/1974) (DENV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.898AlaAla: 5.898 ± 0.0
0.59AlaCys: 0.59 ± 0.0
2.064AlaAsp: 2.064 ± 0.0
2.064AlaGlu: 2.064 ± 0.0
1.474AlaPhe: 1.474 ± 0.0
5.308AlaGly: 5.308 ± 0.0
2.064AlaHis: 2.064 ± 0.0
6.488AlaIle: 6.488 ± 0.0
5.013AlaLys: 5.013 ± 0.0
6.488AlaLeu: 6.488 ± 0.0
2.359AlaMet: 2.359 ± 0.0
2.949AlaAsn: 2.949 ± 0.0
1.474AlaPro: 1.474 ± 0.0
2.654AlaGln: 2.654 ± 0.0
3.539AlaArg: 3.539 ± 0.0
4.718AlaSer: 4.718 ± 0.0
6.488AlaThr: 6.488 ± 0.0
6.193AlaVal: 6.193 ± 0.0
1.769AlaTrp: 1.769 ± 0.0
1.18AlaTyr: 1.18 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.885CysAla: 0.885 ± 0.0
0.295CysCys: 0.295 ± 0.0
0.885CysAsp: 0.885 ± 0.0
0.885CysGlu: 0.885 ± 0.0
0.295CysPhe: 0.295 ± 0.0
2.064CysGly: 2.064 ± 0.0
0.295CysHis: 0.295 ± 0.0
1.769CysIle: 1.769 ± 0.0
0.59CysLys: 0.59 ± 0.0
1.18CysLeu: 1.18 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.295CysAsn: 0.295 ± 0.0
0.885CysPro: 0.885 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.18CysArg: 1.18 ± 0.0
1.18CysSer: 1.18 ± 0.0
1.474CysThr: 1.474 ± 0.0
2.064CysVal: 2.064 ± 0.0
0.59CysTrp: 0.59 ± 0.0
0.59CysTyr: 0.59 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.885AspAla: 0.885 ± 0.0
0.885AspCys: 0.885 ± 0.0
2.359AspAsp: 2.359 ± 0.0
3.244AspGlu: 3.244 ± 0.0
2.359AspPhe: 2.359 ± 0.0
2.949AspGly: 2.949 ± 0.0
0.885AspHis: 0.885 ± 0.0
2.949AspIle: 2.949 ± 0.0
2.064AspLys: 2.064 ± 0.0
5.603AspLeu: 5.603 ± 0.0
1.18AspMet: 1.18 ± 0.0
1.474AspAsn: 1.474 ± 0.0
1.474AspPro: 1.474 ± 0.0
0.885AspGln: 0.885 ± 0.0
2.064AspArg: 2.064 ± 0.0
1.769AspSer: 1.769 ± 0.0
3.539AspThr: 3.539 ± 0.0
3.539AspVal: 3.539 ± 0.0
1.474AspTrp: 1.474 ± 0.0
0.885AspTyr: 0.885 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.308GluAla: 5.308 ± 0.0
0.295GluCys: 0.295 ± 0.0
3.834GluAsp: 3.834 ± 0.0
4.718GluGlu: 4.718 ± 0.0
2.064GluPhe: 2.064 ± 0.0
7.078GluGly: 7.078 ± 0.0
2.359GluHis: 2.359 ± 0.0
2.654GluIle: 2.654 ± 0.0
4.129GluLys: 4.129 ± 0.0
3.539GluLeu: 3.539 ± 0.0
1.769GluMet: 1.769 ± 0.0
3.834GluAsn: 3.834 ± 0.0
4.129GluPro: 4.129 ± 0.0
1.18GluGln: 1.18 ± 0.0
4.423GluArg: 4.423 ± 0.0
2.064GluSer: 2.064 ± 0.0
4.423GluThr: 4.423 ± 0.0
5.898GluVal: 5.898 ± 0.0
0.295GluTrp: 0.295 ± 0.0
0.59GluTyr: 0.59 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.18PheAla: 1.18 ± 0.0
0.59PheCys: 0.59 ± 0.0
0.885PheAsp: 0.885 ± 0.0
1.18PheGlu: 1.18 ± 0.0
0.885PhePhe: 0.885 ± 0.0
2.064PheGly: 2.064 ± 0.0
1.18PheHis: 1.18 ± 0.0
1.18PheIle: 1.18 ± 0.0
4.129PheLys: 4.129 ± 0.0
2.949PheLeu: 2.949 ± 0.0
1.474PheMet: 1.474 ± 0.0
0.885PheAsn: 0.885 ± 0.0
0.885PhePro: 0.885 ± 0.0
1.474PheGln: 1.474 ± 0.0
1.474PheArg: 1.474 ± 0.0
2.359PheSer: 2.359 ± 0.0
3.244PheThr: 3.244 ± 0.0
2.949PheVal: 2.949 ± 0.0
0.885PheTrp: 0.885 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.488GlyAla: 6.488 ± 0.0
1.769GlyCys: 1.769 ± 0.0
2.359GlyAsp: 2.359 ± 0.0
6.193GlyGlu: 6.193 ± 0.0
1.769GlyPhe: 1.769 ± 0.0
4.129GlyGly: 4.129 ± 0.0
1.18GlyHis: 1.18 ± 0.0
5.603GlyIle: 5.603 ± 0.0
8.552GlyLys: 8.552 ± 0.0
7.372GlyLeu: 7.372 ± 0.0
2.359GlyMet: 2.359 ± 0.0
2.949GlyAsn: 2.949 ± 0.0
3.539GlyPro: 3.539 ± 0.0
2.064GlyGln: 2.064 ± 0.0
4.129GlyArg: 4.129 ± 0.0
6.488GlySer: 6.488 ± 0.0
6.488GlyThr: 6.488 ± 0.0
5.308GlyVal: 5.308 ± 0.0
2.359GlyTrp: 2.359 ± 0.0
1.769GlyTyr: 1.769 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.244HisAla: 3.244 ± 0.0
0.295HisCys: 0.295 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.885HisGlu: 0.885 ± 0.0
0.59HisPhe: 0.59 ± 0.0
1.769HisGly: 1.769 ± 0.0
1.18HisHis: 1.18 ± 0.0
0.295HisIle: 0.295 ± 0.0
1.474HisLys: 1.474 ± 0.0
1.18HisLeu: 1.18 ± 0.0
0.295HisMet: 0.295 ± 0.0
0.885HisAsn: 0.885 ± 0.0
0.885HisPro: 0.885 ± 0.0
1.474HisGln: 1.474 ± 0.0
1.474HisArg: 1.474 ± 0.0
0.295HisSer: 0.295 ± 0.0
2.064HisThr: 2.064 ± 0.0
1.18HisVal: 1.18 ± 0.0
0.885HisTrp: 0.885 ± 0.0
0.885HisTyr: 0.885 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.013IleAla: 5.013 ± 0.0
0.59IleCys: 0.59 ± 0.0
1.769IleAsp: 1.769 ± 0.0
3.834IleGlu: 3.834 ± 0.0
2.654IlePhe: 2.654 ± 0.0
5.898IleGly: 5.898 ± 0.0
0.885IleHis: 0.885 ± 0.0
3.244IleIle: 3.244 ± 0.0
1.769IleLys: 1.769 ± 0.0
6.193IleLeu: 6.193 ± 0.0
3.834IleMet: 3.834 ± 0.0
0.885IleAsn: 0.885 ± 0.0
3.244IlePro: 3.244 ± 0.0
1.474IleGln: 1.474 ± 0.0
2.064IleArg: 2.064 ± 0.0
4.423IleSer: 4.423 ± 0.0
3.244IleThr: 3.244 ± 0.0
4.129IleVal: 4.129 ± 0.0
1.769IleTrp: 1.769 ± 0.0
0.885IleTyr: 0.885 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.244LysAla: 3.244 ± 0.0
1.769LysCys: 1.769 ± 0.0
2.654LysAsp: 2.654 ± 0.0
3.539LysGlu: 3.539 ± 0.0
1.474LysPhe: 1.474 ± 0.0
4.129LysGly: 4.129 ± 0.0
0.885LysHis: 0.885 ± 0.0
3.539LysIle: 3.539 ± 0.0
4.718LysLys: 4.718 ± 0.0
5.308LysLeu: 5.308 ± 0.0
2.359LysMet: 2.359 ± 0.0
3.244LysAsn: 3.244 ± 0.0
3.244LysPro: 3.244 ± 0.0
2.359LysGln: 2.359 ± 0.0
5.013LysArg: 5.013 ± 0.0
3.834LysSer: 3.834 ± 0.0
5.308LysThr: 5.308 ± 0.0
2.654LysVal: 2.654 ± 0.0
0.295LysTrp: 0.295 ± 0.0
0.885LysTyr: 0.885 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
7.372LeuAla: 7.372 ± 0.0
2.949LeuCys: 2.949 ± 0.0
4.718LeuAsp: 4.718 ± 0.0
5.308LeuGlu: 5.308 ± 0.0
2.949LeuPhe: 2.949 ± 0.0
7.667LeuGly: 7.667 ± 0.0
1.769LeuHis: 1.769 ± 0.0
5.013LeuIle: 5.013 ± 0.0
5.898LeuLys: 5.898 ± 0.0
11.501LeuLeu: 11.501 ± 0.0
4.129LeuMet: 4.129 ± 0.0
2.949LeuAsn: 2.949 ± 0.0
3.244LeuPro: 3.244 ± 0.0
0.885LeuGln: 0.885 ± 0.0
5.013LeuArg: 5.013 ± 0.0
5.898LeuSer: 5.898 ± 0.0
7.962LeuThr: 7.962 ± 0.0
5.013LeuVal: 5.013 ± 0.0
2.064LeuTrp: 2.064 ± 0.0
1.18LeuTyr: 1.18 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.834MetAla: 3.834 ± 0.0
0.885MetCys: 0.885 ± 0.0
2.064MetAsp: 2.064 ± 0.0
2.654MetGlu: 2.654 ± 0.0
0.885MetPhe: 0.885 ± 0.0
3.539MetGly: 3.539 ± 0.0
0.295MetHis: 0.295 ± 0.0
2.064MetIle: 2.064 ± 0.0
2.359MetLys: 2.359 ± 0.0
5.013MetLeu: 5.013 ± 0.0
0.885MetMet: 0.885 ± 0.0
0.885MetAsn: 0.885 ± 0.0
0.885MetPro: 0.885 ± 0.0
0.295MetGln: 0.295 ± 0.0
2.064MetArg: 2.064 ± 0.0
1.18MetSer: 1.18 ± 0.0
2.359MetThr: 2.359 ± 0.0
2.654MetVal: 2.654 ± 0.0
1.18MetTrp: 1.18 ± 0.0
1.18MetTyr: 1.18 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.064AsnAla: 2.064 ± 0.0
0.295AsnCys: 0.295 ± 0.0
2.359AsnAsp: 2.359 ± 0.0
3.244AsnGlu: 3.244 ± 0.0
0.59AsnPhe: 0.59 ± 0.0
2.654AsnGly: 2.654 ± 0.0
0.59AsnHis: 0.59 ± 0.0
3.539AsnIle: 3.539 ± 0.0
1.18AsnLys: 1.18 ± 0.0
2.359AsnLeu: 2.359 ± 0.0
2.654AsnMet: 2.654 ± 0.0
1.18AsnAsn: 1.18 ± 0.0
2.949AsnPro: 2.949 ± 0.0
3.244AsnGln: 3.244 ± 0.0
2.359AsnArg: 2.359 ± 0.0
2.064AsnSer: 2.064 ± 0.0
2.359AsnThr: 2.359 ± 0.0
0.59AsnVal: 0.59 ± 0.0
0.295AsnTrp: 0.295 ± 0.0
0.885AsnTyr: 0.885 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.064ProAla: 2.064 ± 0.0
0.59ProCys: 0.59 ± 0.0
1.18ProAsp: 1.18 ± 0.0
4.129ProGlu: 4.129 ± 0.0
1.18ProPhe: 1.18 ± 0.0
3.539ProGly: 3.539 ± 0.0
0.885ProHis: 0.885 ± 0.0
2.064ProIle: 2.064 ± 0.0
1.474ProLys: 1.474 ± 0.0
4.129ProLeu: 4.129 ± 0.0
2.359ProMet: 2.359 ± 0.0
1.474ProAsn: 1.474 ± 0.0
1.769ProPro: 1.769 ± 0.0
1.769ProGln: 1.769 ± 0.0
1.474ProArg: 1.474 ± 0.0
2.949ProSer: 2.949 ± 0.0
3.244ProThr: 3.244 ± 0.0
2.654ProVal: 2.654 ± 0.0
1.474ProTrp: 1.474 ± 0.0
0.885ProTyr: 0.885 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.769GlnAla: 1.769 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.064GlnAsp: 2.064 ± 0.0
1.769GlnGlu: 1.769 ± 0.0
0.295GlnPhe: 0.295 ± 0.0
2.654GlnGly: 2.654 ± 0.0
1.18GlnHis: 1.18 ± 0.0
2.064GlnIle: 2.064 ± 0.0
1.769GlnLys: 1.769 ± 0.0
3.539GlnLeu: 3.539 ± 0.0
0.885GlnMet: 0.885 ± 0.0
1.769GlnAsn: 1.769 ± 0.0
0.59GlnPro: 0.59 ± 0.0
0.59GlnGln: 0.59 ± 0.0
3.539GlnArg: 3.539 ± 0.0
0.59GlnSer: 0.59 ± 0.0
1.474GlnThr: 1.474 ± 0.0
3.244GlnVal: 3.244 ± 0.0
1.18GlnTrp: 1.18 ± 0.0
1.18GlnTyr: 1.18 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.654ArgAla: 2.654 ± 0.0
0.885ArgCys: 0.885 ± 0.0
2.654ArgAsp: 2.654 ± 0.0
4.423ArgGlu: 4.423 ± 0.0
2.654ArgPhe: 2.654 ± 0.0
6.193ArgGly: 6.193 ± 0.0
1.18ArgHis: 1.18 ± 0.0
1.769ArgIle: 1.769 ± 0.0
4.129ArgLys: 4.129 ± 0.0
4.129ArgLeu: 4.129 ± 0.0
1.18ArgMet: 1.18 ± 0.0
2.949ArgAsn: 2.949 ± 0.0
2.064ArgPro: 2.064 ± 0.0
1.18ArgGln: 1.18 ± 0.0
4.718ArgArg: 4.718 ± 0.0
3.834ArgSer: 3.834 ± 0.0
3.539ArgThr: 3.539 ± 0.0
3.834ArgVal: 3.834 ± 0.0
2.064ArgTrp: 2.064 ± 0.0
0.59ArgTyr: 0.59 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.423SerAla: 4.423 ± 0.0
0.885SerCys: 0.885 ± 0.0
1.18SerAsp: 1.18 ± 0.0
3.834SerGlu: 3.834 ± 0.0
1.474SerPhe: 1.474 ± 0.0
7.667SerGly: 7.667 ± 0.0
1.18SerHis: 1.18 ± 0.0
4.129SerIle: 4.129 ± 0.0
2.064SerLys: 2.064 ± 0.0
5.603SerLeu: 5.603 ± 0.0
1.769SerMet: 1.769 ± 0.0
1.769SerAsn: 1.769 ± 0.0
2.359SerPro: 2.359 ± 0.0
3.539SerGln: 3.539 ± 0.0
4.129SerArg: 4.129 ± 0.0
2.654SerSer: 2.654 ± 0.0
2.064SerThr: 2.064 ± 0.0
3.244SerVal: 3.244 ± 0.0
3.244SerTrp: 3.244 ± 0.0
2.654SerTyr: 2.654 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
7.667ThrAla: 7.667 ± 0.0
1.474ThrCys: 1.474 ± 0.0
2.949ThrAsp: 2.949 ± 0.0
4.423ThrGlu: 4.423 ± 0.0
3.244ThrPhe: 3.244 ± 0.0
3.834ThrGly: 3.834 ± 0.0
0.59ThrHis: 0.59 ± 0.0
2.949ThrIle: 2.949 ± 0.0
2.064ThrLys: 2.064 ± 0.0
7.078ThrLeu: 7.078 ± 0.0
3.539ThrMet: 3.539 ± 0.0
1.769ThrAsn: 1.769 ± 0.0
3.834ThrPro: 3.834 ± 0.0
2.359ThrGln: 2.359 ± 0.0
3.834ThrArg: 3.834 ± 0.0
5.308ThrSer: 5.308 ± 0.0
8.552ThrThr: 8.552 ± 0.0
3.539ThrVal: 3.539 ± 0.0
4.423ThrTrp: 4.423 ± 0.0
2.949ThrTyr: 2.949 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.539ValAla: 3.539 ± 0.0
0.885ValCys: 0.885 ± 0.0
3.834ValAsp: 3.834 ± 0.0
5.308ValGlu: 5.308 ± 0.0
2.654ValPhe: 2.654 ± 0.0
5.308ValGly: 5.308 ± 0.0
1.474ValHis: 1.474 ± 0.0
4.129ValIle: 4.129 ± 0.0
3.539ValLys: 3.539 ± 0.0
5.603ValLeu: 5.603 ± 0.0
1.769ValMet: 1.769 ± 0.0
1.769ValAsn: 1.769 ± 0.0
2.654ValPro: 2.654 ± 0.0
2.654ValGln: 2.654 ± 0.0
2.654ValArg: 2.654 ± 0.0
5.013ValSer: 5.013 ± 0.0
6.193ValThr: 6.193 ± 0.0
5.603ValVal: 5.603 ± 0.0
1.474ValTrp: 1.474 ± 0.0
0.885ValTyr: 0.885 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.769TrpAla: 1.769 ± 0.0
1.18TrpCys: 1.18 ± 0.0
1.769TrpAsp: 1.769 ± 0.0
1.769TrpGlu: 1.769 ± 0.0
1.474TrpPhe: 1.474 ± 0.0
1.474TrpGly: 1.474 ± 0.0
0.885TrpHis: 0.885 ± 0.0
1.18TrpIle: 1.18 ± 0.0
2.064TrpLys: 2.064 ± 0.0
2.949TrpLeu: 2.949 ± 0.0
1.18TrpMet: 1.18 ± 0.0
2.949TrpAsn: 2.949 ± 0.0
0.885TrpPro: 0.885 ± 0.0
0.885TrpGln: 0.885 ± 0.0
0.295TrpArg: 0.295 ± 0.0
1.474TrpSer: 1.474 ± 0.0
1.769TrpThr: 1.769 ± 0.0
1.18TrpVal: 1.18 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.885TrpTyr: 0.885 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.474TyrAla: 1.474 ± 0.0
0.295TyrCys: 0.295 ± 0.0
0.885TyrAsp: 0.885 ± 0.0
1.18TyrGlu: 1.18 ± 0.0
0.885TyrPhe: 0.885 ± 0.0
2.949TyrGly: 2.949 ± 0.0
0.295TyrHis: 0.295 ± 0.0
1.18TyrIle: 1.18 ± 0.0
1.474TyrLys: 1.474 ± 0.0
1.769TyrLeu: 1.769 ± 0.0
0.885TyrMet: 0.885 ± 0.0
0.59TyrAsn: 0.59 ± 0.0
0.295TyrPro: 0.295 ± 0.0
1.18TyrGln: 1.18 ± 0.0
1.18TyrArg: 1.18 ± 0.0
1.769TyrSer: 1.769 ± 0.0
0.59TyrThr: 0.59 ± 0.0
1.474TyrVal: 1.474 ± 0.0
0.59TyrTrp: 0.59 ± 0.0
0.295TyrTyr: 0.295 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3392 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski