Amino acid dipepetide frequency for Strigamia maritima (European centipede) (Geophilus maritimus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.644AlaAla: 4.644 ± 0.039	1.156AlaCys: 1.156 ± 0.017	2.95AlaAsp: 2.95 ± 0.021	3.582AlaGlu: 3.582 ± 0.034	2.433AlaPhe: 2.433 ± 0.021	3.026AlaGly: 3.026 ± 0.027	1.31AlaHis: 1.31 ± 0.016	3.659AlaIle: 3.659 ± 0.029	3.729AlaLys: 3.729 ± 0.027	5.294AlaLeu: 5.294 ± 0.035	1.507AlaMet: 1.507 ± 0.017	2.818AlaAsn: 2.818 ± 0.02	2.559AlaPro: 2.559 ± 0.026	2.184AlaGln: 2.184 ± 0.022	2.766AlaArg: 2.766 ± 0.025	4.465AlaSer: 4.465 ± 0.033	3.612AlaThr: 3.612 ± 0.03	4.14AlaVal: 4.14 ± 0.027	0.606AlaTrp: 0.606 ± 0.01	1.622AlaTyr: 1.622 ± 0.018	0.0AlaXaa: 0.0 ± 0.0
Cys	1.199CysAla: 1.199 ± 0.016	0.655CysCys: 0.655 ± 0.019	1.277CysAsp: 1.277 ± 0.023	1.303CysGlu: 1.303 ± 0.02	0.966CysPhe: 0.966 ± 0.013	1.411CysGly: 1.411 ± 0.023	0.63CysHis: 0.63 ± 0.012	1.32CysIle: 1.32 ± 0.021	1.375CysLys: 1.375 ± 0.023	2.082CysLeu: 2.082 ± 0.021	0.446CysMet: 0.446 ± 0.01	1.123CysAsn: 1.123 ± 0.016	1.164CysPro: 1.164 ± 0.026	0.912CysGln: 0.912 ± 0.017	1.214CysArg: 1.214 ± 0.021	1.741CysSer: 1.741 ± 0.019	1.149CysThr: 1.149 ± 0.018	1.421CysVal: 1.421 ± 0.023	0.276CysTrp: 0.276 ± 0.006	0.668CysTyr: 0.668 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	3.032AspAla: 3.032 ± 0.023	1.144AspCys: 1.144 ± 0.02	4.136AspAsp: 4.136 ± 0.036	4.585AspGlu: 4.585 ± 0.038	2.481AspPhe: 2.481 ± 0.019	3.266AspGly: 3.266 ± 0.031	1.143AspHis: 1.143 ± 0.014	3.354AspIle: 3.354 ± 0.027	3.443AspLys: 3.443 ± 0.032	5.018AspLeu: 5.018 ± 0.034	1.193AspMet: 1.193 ± 0.016	2.655AspAsn: 2.655 ± 0.025	2.26AspPro: 2.26 ± 0.019	1.807AspGln: 1.807 ± 0.017	2.377AspArg: 2.377 ± 0.02	4.093AspSer: 4.093 ± 0.031	2.539AspThr: 2.539 ± 0.02	3.893AspVal: 3.893 ± 0.027	0.678AspTrp: 0.678 ± 0.01	1.813AspTyr: 1.813 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	3.571GluAla: 3.571 ± 0.028	1.292GluCys: 1.292 ± 0.024	3.85GluAsp: 3.85 ± 0.031	5.57GluGlu: 5.57 ± 0.057	2.57GluPhe: 2.57 ± 0.021	2.737GluGly: 2.737 ± 0.026	1.296GluHis: 1.296 ± 0.016	4.297GluIle: 4.297 ± 0.035	5.374GluLys: 5.374 ± 0.045	5.699GluLeu: 5.699 ± 0.042	1.867GluMet: 1.867 ± 0.018	4.029GluAsn: 4.029 ± 0.032	2.279GluPro: 2.279 ± 0.023	2.35GluGln: 2.35 ± 0.025	3.229GluArg: 3.229 ± 0.034	4.368GluSer: 4.368 ± 0.032	3.691GluThr: 3.691 ± 0.032	3.759GluVal: 3.759 ± 0.035	0.704GluTrp: 0.704 ± 0.01	1.824GluTyr: 1.824 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	2.446PheAla: 2.446 ± 0.019	1.074PheCys: 1.074 ± 0.014	2.433PheAsp: 2.433 ± 0.022	2.469PheGlu: 2.469 ± 0.02	1.87PhePhe: 1.87 ± 0.018	2.542PheGly: 2.542 ± 0.024	1.149PheHis: 1.149 ± 0.015	2.669PheIle: 2.669 ± 0.024	2.487PheLys: 2.487 ± 0.021	4.126PheLeu: 4.126 ± 0.028	0.928PheMet: 0.928 ± 0.013	2.131PheAsn: 2.131 ± 0.02	1.873PhePro: 1.873 ± 0.016	1.715PheGln: 1.715 ± 0.02	2.06PheArg: 2.06 ± 0.02	3.397PheSer: 3.397 ± 0.024	2.4PheThr: 2.4 ± 0.02	2.858PheVal: 2.858 ± 0.024	0.569PheTrp: 0.569 ± 0.011	1.54PheTyr: 1.54 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	2.855GlyAla: 2.855 ± 0.028	1.115GlyCys: 1.115 ± 0.019	2.855GlyAsp: 2.855 ± 0.028	2.901GlyGlu: 2.901 ± 0.028	2.475GlyPhe: 2.475 ± 0.025	4.011GlyGly: 4.011 ± 0.093	1.496GlyHis: 1.496 ± 0.025	3.295GlyIle: 3.295 ± 0.027	3.572GlyLys: 3.572 ± 0.029	4.602GlyLeu: 4.602 ± 0.03	1.207GlyMet: 1.207 ± 0.016	2.767GlyAsn: 2.767 ± 0.03	2.129GlyPro: 2.129 ± 0.031	2.04GlyGln: 2.04 ± 0.026	2.834GlyArg: 2.834 ± 0.027	4.274GlySer: 4.274 ± 0.038	2.95GlyThr: 2.95 ± 0.024	3.217GlyVal: 3.217 ± 0.025	0.655GlyTrp: 0.655 ± 0.01	1.935GlyTyr: 1.935 ± 0.033	0.001GlyXaa: 0.001 ± 0.0
His	1.245HisAla: 1.245 ± 0.015	0.636HisCys: 0.636 ± 0.011	1.121HisAsp: 1.121 ± 0.013	1.38HisGlu: 1.38 ± 0.014	1.219HisPhe: 1.219 ± 0.014	1.345HisGly: 1.345 ± 0.025	0.929HisHis: 0.929 ± 0.022	1.412HisIle: 1.412 ± 0.015	1.41HisLys: 1.41 ± 0.016	2.67HisLeu: 2.67 ± 0.023	0.607HisMet: 0.607 ± 0.011	1.137HisAsn: 1.137 ± 0.013	1.284HisPro: 1.284 ± 0.017	1.093HisGln: 1.093 ± 0.016	1.392HisArg: 1.392 ± 0.016	1.917HisSer: 1.917 ± 0.021	1.267HisThr: 1.267 ± 0.014	1.645HisVal: 1.645 ± 0.016	0.335HisTrp: 0.335 ± 0.008	0.88HisTyr: 0.88 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.565IleAla: 3.565 ± 0.026	1.417IleCys: 1.417 ± 0.019	3.283IleAsp: 3.283 ± 0.023	3.764IleGlu: 3.764 ± 0.028	2.679IlePhe: 2.679 ± 0.022	3.098IleGly: 3.098 ± 0.021	1.555IleHis: 1.555 ± 0.017	3.821IleIle: 3.821 ± 0.033	3.866IleLys: 3.866 ± 0.03	5.821IleLeu: 5.821 ± 0.037	1.319IleMet: 1.319 ± 0.018	3.123IleAsn: 3.123 ± 0.027	3.094IlePro: 3.094 ± 0.027	2.521IleGln: 2.521 ± 0.02	3.048IleArg: 3.048 ± 0.023	4.741IleSer: 4.741 ± 0.032	3.559IleThr: 3.559 ± 0.031	3.781IleVal: 3.781 ± 0.027	0.662IleTrp: 0.662 ± 0.01	1.94IleTyr: 1.94 ± 0.02	0.001IleXaa: 0.001 ± 0.0
Lys	3.392LysAla: 3.392 ± 0.032	1.555LysCys: 1.555 ± 0.022	3.48LysAsp: 3.48 ± 0.03	4.557LysGlu: 4.557 ± 0.043	2.632LysPhe: 2.632 ± 0.02	2.859LysGly: 2.859 ± 0.027	1.613LysHis: 1.613 ± 0.017	4.319LysIle: 4.319 ± 0.031	5.553LysLys: 5.553 ± 0.05	6.381LysLeu: 6.381 ± 0.047	1.889LysMet: 1.889 ± 0.018	3.592LysAsn: 3.592 ± 0.025	3.151LysPro: 3.151 ± 0.034	2.776LysGln: 2.776 ± 0.023	3.747LysArg: 3.747 ± 0.03	4.978LysSer: 4.978 ± 0.036	3.938LysThr: 3.938 ± 0.028	3.665LysVal: 3.665 ± 0.03	0.83LysTrp: 0.83 ± 0.012	2.143LysTyr: 2.143 ± 0.022	0.001LysXaa: 0.001 ± 0.0
Leu	5.615LeuAla: 5.615 ± 0.033	2.017LeuCys: 2.017 ± 0.02	4.91LeuAsp: 4.91 ± 0.033	5.829LeuGlu: 5.829 ± 0.045	3.848LeuPhe: 3.848 ± 0.032	4.364LeuGly: 4.364 ± 0.031	2.454LeuHis: 2.454 ± 0.02	5.463LeuIle: 5.463 ± 0.034	6.469LeuLys: 6.469 ± 0.045	9.084LeuLeu: 9.084 ± 0.055	2.196LeuMet: 2.196 ± 0.019	4.783LeuAsn: 4.783 ± 0.028	4.635LeuPro: 4.635 ± 0.032	4.336LeuGln: 4.336 ± 0.034	4.923LeuArg: 4.923 ± 0.028	7.204LeuSer: 7.204 ± 0.041	5.355LeuThr: 5.355 ± 0.032	5.543LeuVal: 5.543 ± 0.034	1.021LeuTrp: 1.021 ± 0.013	2.643LeuTyr: 2.643 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.797MetAla: 1.797 ± 0.017	0.515MetCys: 0.515 ± 0.01	1.383MetAsp: 1.383 ± 0.015	1.681MetGlu: 1.681 ± 0.016	0.947MetPhe: 0.947 ± 0.013	1.202MetGly: 1.202 ± 0.015	0.547MetHis: 0.547 ± 0.009	1.214MetIle: 1.214 ± 0.014	1.721MetLys: 1.721 ± 0.019	2.025MetLeu: 2.025 ± 0.02	0.669MetMet: 0.669 ± 0.011	1.225MetAsn: 1.225 ± 0.019	1.094MetPro: 1.094 ± 0.013	1.041MetGln: 1.041 ± 0.014	1.191MetArg: 1.191 ± 0.012	1.939MetSer: 1.939 ± 0.019	1.38MetThr: 1.38 ± 0.016	1.295MetVal: 1.295 ± 0.015	0.277MetTrp: 0.277 ± 0.006	0.71MetTyr: 0.71 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.824AsnAla: 2.824 ± 0.022	1.25AsnCys: 1.25 ± 0.018	2.776AsnAsp: 2.776 ± 0.022	3.431AsnGlu: 3.431 ± 0.026	2.283AsnPhe: 2.283 ± 0.019	3.193AsnGly: 3.193 ± 0.037	1.187AsnHis: 1.187 ± 0.016	3.145AsnIle: 3.145 ± 0.024	3.296AsnLys: 3.296 ± 0.024	4.897AsnLeu: 4.897 ± 0.031	1.205AsnMet: 1.205 ± 0.015	2.958AsnAsn: 2.958 ± 0.03	2.382AsnPro: 2.382 ± 0.029	2.098AsnGln: 2.098 ± 0.019	2.519AsnArg: 2.519 ± 0.023	4.151AsnSer: 4.151 ± 0.028	2.627AsnThr: 2.627 ± 0.021	3.419AsnVal: 3.419 ± 0.024	0.624AsnTrp: 0.624 ± 0.009	1.85AsnTyr: 1.85 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	2.666ProAla: 2.666 ± 0.027	0.842ProCys: 0.842 ± 0.026	2.514ProAsp: 2.514 ± 0.024	2.993ProGlu: 2.993 ± 0.027	1.949ProPhe: 1.949 ± 0.02	2.559ProGly: 2.559 ± 0.044	1.175ProHis: 1.175 ± 0.017	2.778ProIle: 2.778 ± 0.026	2.931ProLys: 2.931 ± 0.032	3.975ProLeu: 3.975 ± 0.025	1.011ProMet: 1.011 ± 0.015	2.459ProAsn: 2.459 ± 0.023	3.698ProPro: 3.698 ± 0.065	1.947ProGln: 1.947 ± 0.029	2.314ProArg: 2.314 ± 0.022	4.031ProSer: 4.031 ± 0.036	3.064ProThr: 3.064 ± 0.039	3.109ProVal: 3.109 ± 0.031	0.469ProTrp: 0.469 ± 0.009	1.372ProTyr: 1.372 ± 0.014	0.001ProXaa: 0.001 ± 0.0
Gln	2.193GlnAla: 2.193 ± 0.023	0.88GlnCys: 0.88 ± 0.017	1.837GlnAsp: 1.837 ± 0.015	2.556GlnGlu: 2.556 ± 0.027	1.708GlnPhe: 1.708 ± 0.018	1.745GlnGly: 1.745 ± 0.019	1.131GlnHis: 1.131 ± 0.017	2.559GlnIle: 2.559 ± 0.022	2.594GlnLys: 2.594 ± 0.026	4.224GlnLeu: 4.224 ± 0.032	1.186GlnMet: 1.186 ± 0.016	2.128GlnAsn: 2.128 ± 0.022	1.923GlnPro: 1.923 ± 0.025	2.665GlnGln: 2.665 ± 0.06	2.258GlnArg: 2.258 ± 0.021	2.982GlnSer: 2.982 ± 0.024	2.408GlnThr: 2.408 ± 0.019	2.448GlnVal: 2.448 ± 0.021	0.509GlnTrp: 0.509 ± 0.009	1.207GlnTyr: 1.207 ± 0.015	0.001GlnXaa: 0.001 ± 0.0
Arg	2.704ArgAla: 2.704 ± 0.023	1.134ArgCys: 1.134 ± 0.017	2.691ArgAsp: 2.691 ± 0.025	3.157ArgGlu: 3.157 ± 0.027	2.15ArgPhe: 2.15 ± 0.019	2.575ArgGly: 2.575 ± 0.026	1.453ArgHis: 1.453 ± 0.014	3.085ArgIle: 3.085 ± 0.022	3.88ArgLys: 3.88 ± 0.027	4.737ArgLeu: 4.737 ± 0.031	1.208ArgMet: 1.208 ± 0.015	2.775ArgAsn: 2.775 ± 0.024	2.328ArgPro: 2.328 ± 0.027	2.255ArgGln: 2.255 ± 0.022	3.592ArgArg: 3.592 ± 0.032	3.856ArgSer: 3.856 ± 0.032	2.654ArgThr: 2.654 ± 0.019	2.95ArgVal: 2.95 ± 0.026	0.619ArgTrp: 0.619 ± 0.011	1.524ArgTyr: 1.524 ± 0.018	0.001ArgXaa: 0.001 ± 0.0
Ser	4.562SerAla: 4.562 ± 0.03	1.733SerCys: 1.733 ± 0.022	4.483SerAsp: 4.483 ± 0.032	4.687SerGlu: 4.687 ± 0.035	3.284SerPhe: 3.284 ± 0.026	4.567SerGly: 4.567 ± 0.038	1.854SerHis: 1.854 ± 0.018	4.395SerIle: 4.395 ± 0.028	4.812SerLys: 4.812 ± 0.034	7.0SerLeu: 7.0 ± 0.036	1.662SerMet: 1.662 ± 0.017	3.963SerAsn: 3.963 ± 0.03	4.125SerPro: 4.125 ± 0.047	3.046SerGln: 3.046 ± 0.024	3.983SerArg: 3.983 ± 0.03	8.042SerSer: 8.042 ± 0.069	4.857SerThr: 4.857 ± 0.034	4.888SerVal: 4.888 ± 0.029	0.909SerTrp: 0.909 ± 0.013	2.261SerTyr: 2.261 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	3.549ThrAla: 3.549 ± 0.023	1.366ThrCys: 1.366 ± 0.021	2.959ThrAsp: 2.959 ± 0.03	3.406ThrGlu: 3.406 ± 0.028	2.412ThrPhe: 2.412 ± 0.02	3.082ThrGly: 3.082 ± 0.026	1.335ThrHis: 1.335 ± 0.016	3.511ThrIle: 3.511 ± 0.028	3.635ThrLys: 3.635 ± 0.029	5.132ThrLeu: 5.132 ± 0.031	1.236ThrMet: 1.236 ± 0.013	2.986ThrAsn: 2.986 ± 0.021	3.152ThrPro: 3.152 ± 0.033	2.098ThrGln: 2.098 ± 0.016	2.687ThrArg: 2.687 ± 0.022	5.037ThrSer: 5.037 ± 0.038	4.203ThrThr: 4.203 ± 0.067	3.736ThrVal: 3.736 ± 0.028	0.668ThrTrp: 0.668 ± 0.011	1.686ThrTyr: 1.686 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	3.981ValAla: 3.981 ± 0.029	1.51ValCys: 1.51 ± 0.024	3.572ValAsp: 3.572 ± 0.026	4.029ValGlu: 4.029 ± 0.036	2.673ValPhe: 2.673 ± 0.023	3.18ValGly: 3.18 ± 0.025	1.54ValHis: 1.54 ± 0.018	3.793ValIle: 3.793 ± 0.027	4.061ValLys: 4.061 ± 0.033	5.683ValLeu: 5.683 ± 0.037	1.477ValMet: 1.477 ± 0.017	3.153ValAsn: 3.153 ± 0.022	2.906ValPro: 2.906 ± 0.024	2.498ValGln: 2.498 ± 0.024	2.942ValArg: 2.942 ± 0.024	4.642ValSer: 4.642 ± 0.033	3.818ValThr: 3.818 ± 0.029	4.412ValVal: 4.412 ± 0.038	0.788ValTrp: 0.788 ± 0.013	2.046ValTyr: 2.046 ± 0.02	0.001ValXaa: 0.001 ± 0.0
Trp	0.591TrpAla: 0.591 ± 0.009	0.259TrpCys: 0.259 ± 0.008	0.675TrpAsp: 0.675 ± 0.01	0.67TrpGlu: 0.67 ± 0.01	0.552TrpPhe: 0.552 ± 0.009	0.529TrpGly: 0.529 ± 0.01	0.299TrpHis: 0.299 ± 0.007	0.789TrpIle: 0.789 ± 0.013	0.912TrpLys: 0.912 ± 0.011	1.185TrpLeu: 1.185 ± 0.016	0.329TrpMet: 0.329 ± 0.008	0.673TrpAsn: 0.673 ± 0.009	0.47TrpPro: 0.47 ± 0.008	0.495TrpGln: 0.495 ± 0.009	0.638TrpArg: 0.638 ± 0.01	0.855TrpSer: 0.855 ± 0.013	0.69TrpThr: 0.69 ± 0.011	0.628TrpVal: 0.628 ± 0.01	0.184TrpTrp: 0.184 ± 0.006	0.362TrpTyr: 0.362 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.633TyrAla: 1.633 ± 0.016	0.778TyrCys: 0.778 ± 0.013	1.724TyrAsp: 1.724 ± 0.018	1.805TyrGlu: 1.805 ± 0.018	1.605TyrPhe: 1.605 ± 0.019	1.891TyrGly: 1.891 ± 0.031	0.827TyrHis: 0.827 ± 0.011	1.781TyrIle: 1.781 ± 0.017	1.928TyrLys: 1.928 ± 0.021	3.055TyrLeu: 3.055 ± 0.023	0.712TyrMet: 0.712 ± 0.012	1.638TyrAsn: 1.638 ± 0.018	1.351TyrPro: 1.351 ± 0.018	1.266TyrGln: 1.266 ± 0.018	1.615TyrArg: 1.615 ± 0.019	2.398TyrSer: 2.398 ± 0.022	1.718TyrThr: 1.718 ± 0.021	1.896TyrVal: 1.896 ± 0.018	0.404TyrTrp: 0.404 ± 0.009	1.23TyrTyr: 1.23 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.058XaaXaa: 0.058 ± 0.02

Statistics based on 14972 proteins (7216300 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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