Amino acid dipepetide frequency for Tessaracoccus lapidicaptus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.577AlaAla: 20.577 ± 0.214	0.971AlaCys: 0.971 ± 0.038	8.748AlaAsp: 8.748 ± 0.113	8.603AlaGlu: 8.603 ± 0.124	3.471AlaPhe: 3.471 ± 0.068	12.159AlaGly: 12.159 ± 0.13	2.682AlaHis: 2.682 ± 0.052	4.961AlaIle: 4.961 ± 0.071	2.737AlaLys: 2.737 ± 0.074	13.67AlaLeu: 13.67 ± 0.152	3.062AlaMet: 3.062 ± 0.059	2.163AlaAsn: 2.163 ± 0.052	6.015AlaPro: 6.015 ± 0.116	3.811AlaGln: 3.811 ± 0.07	9.34AlaArg: 9.34 ± 0.125	6.097AlaSer: 6.097 ± 0.085	7.627AlaThr: 7.627 ± 0.121	12.185AlaVal: 12.185 ± 0.146	2.073AlaTrp: 2.073 ± 0.054	2.276AlaTyr: 2.276 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.771CysAla: 0.771 ± 0.033	0.08CysCys: 0.08 ± 0.01	0.44CysAsp: 0.44 ± 0.024	0.363CysGlu: 0.363 ± 0.021	0.188CysPhe: 0.188 ± 0.014	0.736CysGly: 0.736 ± 0.035	0.168CysHis: 0.168 ± 0.014	0.191CysIle: 0.191 ± 0.015	0.072CysLys: 0.072 ± 0.008	0.58CysLeu: 0.58 ± 0.025	0.118CysMet: 0.118 ± 0.011	0.137CysAsn: 0.137 ± 0.012	0.447CysPro: 0.447 ± 0.024	0.173CysGln: 0.173 ± 0.014	0.515CysArg: 0.515 ± 0.027	0.382CysSer: 0.382 ± 0.021	0.387CysThr: 0.387 ± 0.019	0.531CysVal: 0.531 ± 0.022	0.084CysTrp: 0.084 ± 0.01	0.169CysTyr: 0.169 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.355AspAla: 8.355 ± 0.1	0.32AspCys: 0.32 ± 0.017	4.435AspAsp: 4.435 ± 0.093	4.494AspGlu: 4.494 ± 0.073	1.728AspPhe: 1.728 ± 0.043	6.538AspGly: 6.538 ± 0.113	1.447AspHis: 1.447 ± 0.043	2.316AspIle: 2.316 ± 0.051	1.054AspLys: 1.054 ± 0.039	7.072AspLeu: 7.072 ± 0.094	1.012AspMet: 1.012 ± 0.032	1.048AspAsn: 1.048 ± 0.04	4.327AspPro: 4.327 ± 0.075	1.736AspGln: 1.736 ± 0.048	4.49AspArg: 4.49 ± 0.087	2.372AspSer: 2.372 ± 0.05	2.951AspThr: 2.951 ± 0.053	5.908AspVal: 5.908 ± 0.074	0.915AspTrp: 0.915 ± 0.034	1.327AspTyr: 1.327 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	7.699GluAla: 7.699 ± 0.103	0.36GluCys: 0.36 ± 0.019	2.913GluAsp: 2.913 ± 0.063	3.277GluGlu: 3.277 ± 0.075	1.758GluPhe: 1.758 ± 0.049	4.272GluGly: 4.272 ± 0.071	1.407GluHis: 1.407 ± 0.043	2.567GluIle: 2.567 ± 0.046	1.181GluLys: 1.181 ± 0.043	6.531GluLeu: 6.531 ± 0.089	1.107GluMet: 1.107 ± 0.034	0.952GluAsn: 0.952 ± 0.031	3.125GluPro: 3.125 ± 0.071	2.005GluGln: 2.005 ± 0.05	5.001GluArg: 5.001 ± 0.09	2.77GluSer: 2.77 ± 0.063	2.876GluThr: 2.876 ± 0.058	5.206GluVal: 5.206 ± 0.081	0.848GluTrp: 0.848 ± 0.033	1.088GluTyr: 1.088 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.851PheAla: 3.851 ± 0.072	0.226PheCys: 0.226 ± 0.015	2.38PheAsp: 2.38 ± 0.056	1.563PheGlu: 1.563 ± 0.04	0.923PhePhe: 0.923 ± 0.034	3.098PheGly: 3.098 ± 0.066	0.67PheHis: 0.67 ± 0.028	1.113PheIle: 1.113 ± 0.041	0.522PheLys: 0.522 ± 0.033	2.776PheLeu: 2.776 ± 0.062	0.546PheMet: 0.546 ± 0.026	0.696PheAsn: 0.696 ± 0.031	1.363PhePro: 1.363 ± 0.039	0.761PheGln: 0.761 ± 0.028	1.771PheArg: 1.771 ± 0.044	1.561PheSer: 1.561 ± 0.037	1.981PheThr: 1.981 ± 0.052	2.614PheVal: 2.614 ± 0.059	0.452PheTrp: 0.452 ± 0.024	0.62PheTyr: 0.62 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.239GlyAla: 10.239 ± 0.123	0.722GlyCys: 0.722 ± 0.027	5.316GlyAsp: 5.316 ± 0.085	4.888GlyGlu: 4.888 ± 0.075	3.14GlyPhe: 3.14 ± 0.056	7.39GlyGly: 7.39 ± 0.115	2.118GlyHis: 2.118 ± 0.051	4.065GlyIle: 4.065 ± 0.075	2.018GlyLys: 2.018 ± 0.061	9.518GlyLeu: 9.518 ± 0.128	2.213GlyMet: 2.213 ± 0.052	1.708GlyAsn: 1.708 ± 0.045	4.082GlyPro: 4.082 ± 0.071	2.675GlyGln: 2.675 ± 0.062	7.132GlyArg: 7.132 ± 0.093	4.93GlySer: 4.93 ± 0.067	5.253GlyThr: 5.253 ± 0.082	8.345GlyVal: 8.345 ± 0.111	1.744GlyTrp: 1.744 ± 0.045	2.307GlyTyr: 2.307 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.404HisAla: 2.404 ± 0.053	0.164HisCys: 0.164 ± 0.014	1.453HisAsp: 1.453 ± 0.039	1.258HisGlu: 1.258 ± 0.043	0.56HisPhe: 0.56 ± 0.026	2.102HisGly: 2.102 ± 0.052	0.683HisHis: 0.683 ± 0.028	0.815HisIle: 0.815 ± 0.032	0.308HisLys: 0.308 ± 0.02	2.437HisLeu: 2.437 ± 0.056	0.38HisMet: 0.38 ± 0.022	0.39HisAsn: 0.39 ± 0.022	1.625HisPro: 1.625 ± 0.049	0.584HisGln: 0.584 ± 0.022	1.89HisArg: 1.89 ± 0.051	0.958HisSer: 0.958 ± 0.034	1.098HisThr: 1.098 ± 0.033	1.854HisVal: 1.854 ± 0.048	0.295HisTrp: 0.295 ± 0.02	0.464HisTyr: 0.464 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.725IleAla: 5.725 ± 0.089	0.306IleCys: 0.306 ± 0.019	3.133IleAsp: 3.133 ± 0.059	2.551IleGlu: 2.551 ± 0.054	1.04IlePhe: 1.04 ± 0.037	3.957IleGly: 3.957 ± 0.072	0.758IleHis: 0.758 ± 0.029	1.71IleIle: 1.71 ± 0.063	0.848IleLys: 0.848 ± 0.035	3.546IleLeu: 3.546 ± 0.071	0.715IleMet: 0.715 ± 0.03	0.964IleAsn: 0.964 ± 0.033	2.148IlePro: 2.148 ± 0.051	0.92IleGln: 0.92 ± 0.034	2.532IleArg: 2.532 ± 0.055	2.018IleSer: 2.018 ± 0.047	2.557IleThr: 2.557 ± 0.06	3.86IleVal: 3.86 ± 0.072	0.52IleTrp: 0.52 ± 0.025	0.751IleTyr: 0.751 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.66LysAla: 2.66 ± 0.065	0.102LysCys: 0.102 ± 0.011	1.039LysAsp: 1.039 ± 0.039	0.985LysGlu: 0.985 ± 0.036	0.537LysPhe: 0.537 ± 0.027	1.571LysGly: 1.571 ± 0.055	0.392LysHis: 0.392 ± 0.018	0.874LysIle: 0.874 ± 0.036	0.684LysLys: 0.684 ± 0.03	1.847LysLeu: 1.847 ± 0.055	0.419LysMet: 0.419 ± 0.024	0.46LysAsn: 0.46 ± 0.023	1.126LysPro: 1.126 ± 0.041	0.615LysGln: 0.615 ± 0.032	1.431LysArg: 1.431 ± 0.046	1.008LysSer: 1.008 ± 0.036	1.155LysThr: 1.155 ± 0.041	1.874LysVal: 1.874 ± 0.049	0.225LysTrp: 0.225 ± 0.017	0.457LysTyr: 0.457 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	15.141LeuAla: 15.141 ± 0.144	0.585LeuCys: 0.585 ± 0.025	6.864LeuAsp: 6.864 ± 0.089	5.134LeuGlu: 5.134 ± 0.073	2.607LeuPhe: 2.607 ± 0.063	9.74LeuGly: 9.74 ± 0.112	2.018LeuHis: 2.018 ± 0.051	4.293LeuIle: 4.293 ± 0.078	1.863LeuLys: 1.863 ± 0.054	10.486LeuLeu: 10.486 ± 0.143	1.948LeuMet: 1.948 ± 0.045	1.874LeuAsn: 1.874 ± 0.044	5.999LeuPro: 5.999 ± 0.084	2.543LeuGln: 2.543 ± 0.053	7.868LeuArg: 7.868 ± 0.126	5.476LeuSer: 5.476 ± 0.078	6.98LeuThr: 6.98 ± 0.08	9.126LeuVal: 9.126 ± 0.108	1.239LeuTrp: 1.239 ± 0.037	1.676LeuTyr: 1.676 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	2.815MetAla: 2.815 ± 0.059	0.118MetCys: 0.118 ± 0.011	1.03MetAsp: 1.03 ± 0.033	0.878MetGlu: 0.878 ± 0.034	0.607MetPhe: 0.607 ± 0.025	1.642MetGly: 1.642 ± 0.047	0.393MetHis: 0.393 ± 0.021	0.922MetIle: 0.922 ± 0.036	0.459MetLys: 0.459 ± 0.022	2.043MetLeu: 2.043 ± 0.053	0.419MetMet: 0.419 ± 0.025	0.517MetAsn: 0.517 ± 0.022	1.141MetPro: 1.141 ± 0.036	0.545MetGln: 0.545 ± 0.024	1.56MetArg: 1.56 ± 0.042	1.478MetSer: 1.478 ± 0.036	1.702MetThr: 1.702 ± 0.043	1.75MetVal: 1.75 ± 0.052	0.271MetTrp: 0.271 ± 0.015	0.329MetTyr: 0.329 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.23AsnAla: 2.23 ± 0.052	0.135AsnCys: 0.135 ± 0.012	1.073AsnAsp: 1.073 ± 0.035	0.936AsnGlu: 0.936 ± 0.032	0.583AsnPhe: 0.583 ± 0.025	1.679AsnGly: 1.679 ± 0.05	0.415AsnHis: 0.415 ± 0.023	0.847AsnIle: 0.847 ± 0.028	0.368AsnLys: 0.368 ± 0.023	1.999AsnLeu: 1.999 ± 0.051	0.354AsnMet: 0.354 ± 0.02	0.483AsnAsn: 0.483 ± 0.026	1.543AsnPro: 1.543 ± 0.043	0.598AsnGln: 0.598 ± 0.031	1.309AsnArg: 1.309 ± 0.032	0.91AsnSer: 0.91 ± 0.031	1.074AsnThr: 1.074 ± 0.04	1.55AsnVal: 1.55 ± 0.047	0.317AsnTrp: 0.317 ± 0.018	0.494AsnTyr: 0.494 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	7.264ProAla: 7.264 ± 0.1	0.29ProCys: 0.29 ± 0.017	4.224ProAsp: 4.224 ± 0.067	3.877ProGlu: 3.877 ± 0.065	1.536ProPhe: 1.536 ± 0.043	5.459ProGly: 5.459 ± 0.076	1.181ProHis: 1.181 ± 0.034	1.763ProIle: 1.763 ± 0.048	1.038ProLys: 1.038 ± 0.042	4.945ProLeu: 4.945 ± 0.077	1.115ProMet: 1.115 ± 0.03	0.987ProAsn: 0.987 ± 0.03	2.52ProPro: 2.52 ± 0.065	1.464ProGln: 1.464 ± 0.041	3.518ProArg: 3.518 ± 0.067	3.16ProSer: 3.16 ± 0.076	3.593ProThr: 3.593 ± 0.071	4.903ProVal: 4.903 ± 0.075	0.895ProTrp: 0.895 ± 0.031	1.067ProTyr: 1.067 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.622GlnAla: 3.622 ± 0.068	0.13GlnCys: 0.13 ± 0.011	1.221GlnAsp: 1.221 ± 0.035	1.372GlnGlu: 1.372 ± 0.036	0.856GlnPhe: 0.856 ± 0.032	2.13GlnGly: 2.13 ± 0.051	0.696GlnHis: 0.696 ± 0.028	1.258GlnIle: 1.258 ± 0.037	0.543GlnLys: 0.543 ± 0.023	3.33GlnLeu: 3.33 ± 0.077	0.598GlnMet: 0.598 ± 0.025	0.507GlnAsn: 0.507 ± 0.024	1.642GlnPro: 1.642 ± 0.044	1.06GlnGln: 1.06 ± 0.036	2.441GlnArg: 2.441 ± 0.054	1.3GlnSer: 1.3 ± 0.037	1.33GlnThr: 1.33 ± 0.038	2.649GlnVal: 2.649 ± 0.054	0.487GlnTrp: 0.487 ± 0.026	0.572GlnTyr: 0.572 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	9.028ArgAla: 9.028 ± 0.136	0.457ArgCys: 0.457 ± 0.022	4.609ArgAsp: 4.609 ± 0.073	4.191ArgGlu: 4.191 ± 0.069	2.418ArgPhe: 2.418 ± 0.045	5.434ArgGly: 5.434 ± 0.085	1.848ArgHis: 1.848 ± 0.052	3.497ArgIle: 3.497 ± 0.061	1.34ArgLys: 1.34 ± 0.043	8.13ArgLeu: 8.13 ± 0.112	1.801ArgMet: 1.801 ± 0.041	1.308ArgAsn: 1.308 ± 0.038	4.215ArgPro: 4.215 ± 0.073	2.255ArgGln: 2.255 ± 0.06	7.232ArgArg: 7.232 ± 0.1	3.851ArgSer: 3.851 ± 0.062	4.09ArgThr: 4.09 ± 0.07	6.145ArgVal: 6.145 ± 0.09	1.323ArgTrp: 1.323 ± 0.04	1.777ArgTyr: 1.777 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.248SerAla: 6.248 ± 0.08	0.319SerCys: 0.319 ± 0.018	2.954SerAsp: 2.954 ± 0.052	2.5SerGlu: 2.5 ± 0.059	1.708SerPhe: 1.708 ± 0.047	5.295SerGly: 5.295 ± 0.087	1.029SerHis: 1.029 ± 0.033	2.039SerIle: 2.039 ± 0.048	0.965SerLys: 0.965 ± 0.033	5.13SerLeu: 5.13 ± 0.073	1.275SerMet: 1.275 ± 0.035	0.943SerAsn: 0.943 ± 0.036	2.991SerPro: 2.991 ± 0.076	1.293SerGln: 1.293 ± 0.041	3.836SerArg: 3.836 ± 0.064	2.966SerSer: 2.966 ± 0.07	3.154SerThr: 3.154 ± 0.06	4.391SerVal: 4.391 ± 0.069	0.889SerTrp: 0.889 ± 0.033	1.189SerTyr: 1.189 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	7.423ThrAla: 7.423 ± 0.118	0.415ThrCys: 0.415 ± 0.024	3.544ThrAsp: 3.544 ± 0.063	2.871ThrGlu: 2.871 ± 0.066	1.879ThrPhe: 1.879 ± 0.053	5.736ThrGly: 5.736 ± 0.089	1.233ThrHis: 1.233 ± 0.038	2.41ThrIle: 2.41 ± 0.061	1.127ThrLys: 1.127 ± 0.039	6.129ThrLeu: 6.129 ± 0.072	1.253ThrMet: 1.253 ± 0.042	1.186ThrAsn: 1.186 ± 0.042	3.935ThrPro: 3.935 ± 0.064	1.555ThrGln: 1.555 ± 0.041	3.926ThrArg: 3.926 ± 0.066	3.121ThrSer: 3.121 ± 0.059	3.825ThrThr: 3.825 ± 0.078	6.066ThrVal: 6.066 ± 0.093	0.968ThrTrp: 0.968 ± 0.032	1.249ThrTyr: 1.249 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	13.066ValAla: 13.066 ± 0.138	0.553ValCys: 0.553 ± 0.025	6.356ValAsp: 6.356 ± 0.084	5.383ValGlu: 5.383 ± 0.081	2.611ValPhe: 2.611 ± 0.06	7.789ValGly: 7.789 ± 0.105	1.776ValHis: 1.776 ± 0.047	3.678ValIle: 3.678 ± 0.068	1.668ValLys: 1.668 ± 0.056	9.171ValLeu: 9.171 ± 0.111	1.684ValMet: 1.684 ± 0.047	1.788ValAsn: 1.788 ± 0.042	4.687ValPro: 4.687 ± 0.064	1.94ValGln: 1.94 ± 0.044	6.103ValArg: 6.103 ± 0.095	4.828ValSer: 4.828 ± 0.082	6.148ValThr: 6.148 ± 0.092	9.494ValVal: 9.494 ± 0.132	1.204ValTrp: 1.204 ± 0.044	1.486ValTyr: 1.486 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	1.745TrpAla: 1.745 ± 0.045	0.111TrpCys: 0.111 ± 0.013	0.853TrpAsp: 0.853 ± 0.032	0.701TrpGlu: 0.701 ± 0.029	0.59TrpPhe: 0.59 ± 0.026	1.188TrpGly: 1.188 ± 0.038	0.369TrpHis: 0.369 ± 0.021	0.605TrpIle: 0.605 ± 0.027	0.317TrpLys: 0.317 ± 0.018	1.864TrpLeu: 1.864 ± 0.047	0.341TrpMet: 0.341 ± 0.019	0.345TrpAsn: 0.345 ± 0.018	0.764TrpPro: 0.764 ± 0.032	0.6TrpGln: 0.6 ± 0.027	1.335TrpArg: 1.335 ± 0.04	0.867TrpSer: 0.867 ± 0.028	0.935TrpThr: 0.935 ± 0.029	1.22TrpVal: 1.22 ± 0.04	0.4TrpTrp: 0.4 ± 0.025	0.321TrpTyr: 0.321 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.362TyrAla: 2.362 ± 0.047	0.166TyrCys: 0.166 ± 0.014	1.262TyrAsp: 1.262 ± 0.04	1.116TyrGlu: 1.116 ± 0.04	0.747TyrPhe: 0.747 ± 0.031	1.889TyrGly: 1.889 ± 0.049	0.439TyrHis: 0.439 ± 0.02	0.636TyrIle: 0.636 ± 0.024	0.347TyrLys: 0.347 ± 0.022	2.256TyrLeu: 2.256 ± 0.057	0.259TyrMet: 0.259 ± 0.017	0.44TyrAsn: 0.44 ± 0.022	1.107TyrPro: 1.107 ± 0.037	0.612TyrGln: 0.612 ± 0.026	1.719TyrArg: 1.719 ± 0.044	1.061TyrSer: 1.061 ± 0.036	1.135TyrThr: 1.135 ± 0.04	1.741TyrVal: 1.741 ± 0.044	0.325TyrTrp: 0.325 ± 0.02	0.483TyrTyr: 0.483 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2736 proteins (921061 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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