Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus; Human alphaherpesvirus 3

Average proteome isoelectric point is 7.06

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q9E2H5|ORF0_VZVO Membrane protein 0 OS=Varicella-zoster virus (strain Oka vaccine) OX=341980 GN=ORF0 PE=1 SV=1
MM1 pKa = 7.17ATVHH5 pKa = 5.56YY6 pKa = 9.68SRR8 pKa = 11.84RR9 pKa = 11.84PGTPPVTLTSSPGMDD24 pKa = 4.22DD25 pKa = 3.25VATPIPYY32 pKa = 10.33LPTYY36 pKa = 10.74AEE38 pKa = 4.51AVADD42 pKa = 4.08APPPYY47 pKa = 9.66RR48 pKa = 11.84SRR50 pKa = 11.84EE51 pKa = 4.07SLVFSPPLFPHH62 pKa = 6.43VEE64 pKa = 4.01NGTTQQSYY72 pKa = 11.38DD73 pKa = 4.37CLDD76 pKa = 3.59CAYY79 pKa = 10.67DD80 pKa = 4.6GIHH83 pKa = 6.79RR84 pKa = 11.84LQLAFLRR91 pKa = 11.84IRR93 pKa = 11.84KK94 pKa = 8.92CCVPAFLILFGILTLTAVVVAIVAVFPEE122 pKa = 4.65EE123 pKa = 4.4PPNSTTRR130 pKa = 11.84NYY132 pKa = 10.3CPEE135 pKa = 4.0GEE137 pKa = 4.6GIYY140 pKa = 10.66SRR142 pKa = 11.84LQLVARR148 pKa = 11.84VCTTKK153 pKa = 10.75AIYY156 pKa = 7.99VTKK159 pKa = 10.52ANVAIWSTTPSTLHH173 pKa = 6.28NLSICIFSCADD184 pKa = 2.76AFLRR188 pKa = 11.84DD189 pKa = 3.74RR190 pKa = 11.84GLGTSTSGIRR200 pKa = 11.84TAGGLARR207 pKa = 11.84TTSGDD212 pKa = 3.43ALFCISSVCC221 pKa = 4.19

Molecular weight: 23.83 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q9E2H5|ORF0_VZVO Membrane protein 0 OS=Varicella-zoster virus (strain Oka vaccine) OX=341980 GN=ORF0 PE=1 SV=1
MM1 pKa = 7.17ATVHH5 pKa = 5.56YY6 pKa = 9.68SRR8 pKa = 11.84RR9 pKa = 11.84PGTPPVTLTSSPGMDD24 pKa = 4.22DD25 pKa = 3.25VATPIPYY32 pKa = 10.33LPTYY36 pKa = 10.74AEE38 pKa = 4.51AVADD42 pKa = 4.08APPPYY47 pKa = 9.66RR48 pKa = 11.84SRR50 pKa = 11.84EE51 pKa = 4.07SLVFSPPLFPHH62 pKa = 6.43VEE64 pKa = 4.01NGTTQQSYY72 pKa = 11.38DD73 pKa = 4.37CLDD76 pKa = 3.59CAYY79 pKa = 10.67DD80 pKa = 4.6GIHH83 pKa = 6.79RR84 pKa = 11.84LQLAFLRR91 pKa = 11.84IRR93 pKa = 11.84KK94 pKa = 8.92CCVPAFLILFGILTLTAVVVAIVAVFPEE122 pKa = 4.65EE123 pKa = 4.4PPNSTTRR130 pKa = 11.84NYY132 pKa = 10.3CPEE135 pKa = 4.0GEE137 pKa = 4.6GIYY140 pKa = 10.66SRR142 pKa = 11.84LQLVARR148 pKa = 11.84VCTTKK153 pKa = 10.75AIYY156 pKa = 7.99VTKK159 pKa = 10.52ANVAIWSTTPSTLHH173 pKa = 6.28NLSICIFSCADD184 pKa = 2.76AFLRR188 pKa = 11.84DD189 pKa = 3.74RR190 pKa = 11.84GLGTSTSGIRR200 pKa = 11.84TAGGLARR207 pKa = 11.84TTSGDD212 pKa = 3.43ALFCISSVCC221 pKa = 4.19

Molecular weight: 23.83 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

221

221

221

221.0

23.83

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.502 ± 0.0

4.525 ± 0.0

4.072 ± 0.0

3.167 ± 0.0

4.072 ± 0.0

5.882 ± 0.0

1.81 ± 0.0

5.882 ± 0.0

1.357 ± 0.0

9.05 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

0.905 ± 0.0

2.262 ± 0.0

8.597 ± 0.0

1.81 ± 0.0

6.335 ± 0.0

8.145 ± 0.0

10.407 ± 0.0

7.692 ± 0.0

0.452 ± 0.0

4.072 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski