Common vole polyomavirus

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Sepolyvirales; Polyomaviridae; Betapolyomavirus; Microtus arvalis polyomavirus 1

Average proteome isoelectric point is 6.12

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A0P0I7J3|A0A0P0I7J3_9POLY Major capsid protein VP1 OS=Common vole polyomavirus OX=1737523 PE=3 SV=1
MM1 pKa = 7.61GIVLALPEE9 pKa = 4.66FIAAAVAGGAEE20 pKa = 4.11ALEE23 pKa = 4.37IAGSVGALVEE33 pKa = 4.49GAADD37 pKa = 3.39TAAAIGTTAEE47 pKa = 4.22VLGEE51 pKa = 4.15SLPVTISEE59 pKa = 4.21AAATVLAQTPEE70 pKa = 4.05VVEE73 pKa = 4.06ALNAGGQAVGSAVSLGSGLYY93 pKa = 9.21QAISNTDD100 pKa = 3.61PQSGTHH106 pKa = 6.94GISDD110 pKa = 4.72RR111 pKa = 11.84IGMANALVPYY121 pKa = 9.38QQVPTYY127 pKa = 9.71LQWLRR132 pKa = 11.84NILSYY137 pKa = 10.76IPTVQQIWGGLEE149 pKa = 3.85RR150 pKa = 11.84ATQTYY155 pKa = 10.19QYY157 pKa = 10.95LDD159 pKa = 3.2EE160 pKa = 4.24QYY162 pKa = 11.19RR163 pKa = 11.84LRR165 pKa = 11.84EE166 pKa = 3.84QQYY169 pKa = 9.13EE170 pKa = 3.98RR171 pKa = 11.84LIAEE175 pKa = 4.61FEE177 pKa = 4.23RR178 pKa = 11.84GVNSGPVAGVIEE190 pKa = 5.2RR191 pKa = 11.84IRR193 pKa = 11.84ATALEE198 pKa = 4.4RR199 pKa = 11.84EE200 pKa = 4.57LEE202 pKa = 4.28VQRR205 pKa = 11.84IAGDD209 pKa = 3.51VRR211 pKa = 11.84DD212 pKa = 3.46VSTNLRR218 pKa = 11.84EE219 pKa = 4.19GLSASGRR226 pKa = 11.84AVANVGSALYY236 pKa = 8.68NTVSGAASATRR247 pKa = 11.84AAAGTLGGTVSNVVGHH263 pKa = 5.12VQGTISTIQDD273 pKa = 3.48YY274 pKa = 11.11LRR276 pKa = 11.84TIGSEE281 pKa = 3.71ASGVSTTMLTDD292 pKa = 4.77GYY294 pKa = 10.95NAMPRR299 pKa = 11.84GISNFGSWVFMSGSDD314 pKa = 3.28GGTPHH319 pKa = 6.94YY320 pKa = 11.02SLDD323 pKa = 3.45YY324 pKa = 8.27WVVYY328 pKa = 10.47ALEE331 pKa = 4.31EE332 pKa = 4.02ALKK335 pKa = 10.26PLYY338 pKa = 9.31STQNAPVEE346 pKa = 4.47STVEE350 pKa = 4.07DD351 pKa = 3.92EE352 pKa = 6.09DD353 pKa = 4.28DD354 pKa = 4.03TEE356 pKa = 4.35HH357 pKa = 7.11TPTKK361 pKa = 10.2NNKK364 pKa = 7.88KK365 pKa = 8.95RR366 pKa = 11.84RR367 pKa = 11.84RR368 pKa = 11.84RR369 pKa = 11.84SVVSRR374 pKa = 11.84PSKK377 pKa = 9.43RR378 pKa = 11.84RR379 pKa = 11.84HH380 pKa = 5.7RR381 pKa = 11.84SASS384 pKa = 3.25

Molecular weight:
40.58 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A0P0HGX9|A0A0P0HGX9_9POLY Large T antigen OS=Common vole polyomavirus OX=1737523 PE=4 SV=1
MM1 pKa = 7.56ANALVPYY8 pKa = 9.38QQVPTYY14 pKa = 9.71LQWLRR19 pKa = 11.84NILSYY24 pKa = 10.76IPTVQQIWGGLEE36 pKa = 3.85RR37 pKa = 11.84ATQTYY42 pKa = 10.19QYY44 pKa = 10.95LDD46 pKa = 3.2EE47 pKa = 4.24QYY49 pKa = 11.19RR50 pKa = 11.84LRR52 pKa = 11.84EE53 pKa = 3.84QQYY56 pKa = 9.13EE57 pKa = 3.98RR58 pKa = 11.84LIAEE62 pKa = 4.61FEE64 pKa = 4.23RR65 pKa = 11.84GVNSGPVAGVIEE77 pKa = 5.2RR78 pKa = 11.84IRR80 pKa = 11.84ATALEE85 pKa = 4.4RR86 pKa = 11.84EE87 pKa = 4.57LEE89 pKa = 4.28VQRR92 pKa = 11.84IAGDD96 pKa = 3.51VRR98 pKa = 11.84DD99 pKa = 3.46VSTNLRR105 pKa = 11.84EE106 pKa = 4.19GLSASGRR113 pKa = 11.84AVANVGSALYY123 pKa = 8.68NTVSGAASATRR134 pKa = 11.84AAAGTLGGTVSNVVGHH150 pKa = 5.12VQGTISTIQDD160 pKa = 3.48YY161 pKa = 11.11LRR163 pKa = 11.84TIGSEE168 pKa = 3.71ASGVSTTMLTDD179 pKa = 4.77GYY181 pKa = 10.95NAMPRR186 pKa = 11.84GISNFGSWVFMSGSDD201 pKa = 3.28GGTPHH206 pKa = 6.94YY207 pKa = 11.02SLDD210 pKa = 3.45YY211 pKa = 8.27WVVYY215 pKa = 10.47ALEE218 pKa = 4.31EE219 pKa = 4.02ALKK222 pKa = 10.26PLYY225 pKa = 9.31STQNAPVEE233 pKa = 4.47STVEE237 pKa = 4.07DD238 pKa = 3.92EE239 pKa = 6.09DD240 pKa = 4.28DD241 pKa = 4.03TEE243 pKa = 4.35HH244 pKa = 7.11TPTKK248 pKa = 10.2NNKK251 pKa = 7.88KK252 pKa = 8.95RR253 pKa = 11.84RR254 pKa = 11.84RR255 pKa = 11.84RR256 pKa = 11.84SVVSRR261 pKa = 11.84PSKK264 pKa = 9.43RR265 pKa = 11.84RR266 pKa = 11.84HH267 pKa = 5.7RR268 pKa = 11.84SASS271 pKa = 3.25

Molecular weight:
29.87 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

1844

189

646

368.8

41.52

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.941 ± 1.522

2.223 ± 0.95

4.284 ± 0.527

7.646 ± 0.37

3.416 ± 0.852

6.941 ± 1.106

2.115 ± 0.558

4.826 ± 0.23

4.61 ± 1.355

8.785 ± 0.787

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.44 ± 0.411

5.043 ± 0.41

4.555 ± 0.84

4.393 ± 0.196

6.345 ± 0.589

6.996 ± 0.667

5.911 ± 0.982

7.05 ± 1.081

1.735 ± 0.379

3.742 ± 0.369

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski