Amino acid dipepetide frequency for Pansavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.147AlaAla: 4.147 ± 0.0
1.037AlaCys: 1.037 ± 0.0
2.073AlaAsp: 2.073 ± 0.0
2.073AlaGlu: 2.073 ± 0.0
4.492AlaPhe: 4.492 ± 0.0
5.529AlaGly: 5.529 ± 0.0
2.764AlaHis: 2.764 ± 0.0
2.764AlaIle: 2.764 ± 0.0
1.382AlaLys: 1.382 ± 0.0
6.565AlaLeu: 6.565 ± 0.0
2.419AlaMet: 2.419 ± 0.0
3.11AlaAsn: 3.11 ± 0.0
5.529AlaPro: 5.529 ± 0.0
3.11AlaGln: 3.11 ± 0.0
5.874AlaArg: 5.874 ± 0.0
5.874AlaSer: 5.874 ± 0.0
3.801AlaThr: 3.801 ± 0.0
3.11AlaVal: 3.11 ± 0.0
1.382AlaTrp: 1.382 ± 0.0
1.382AlaTyr: 1.382 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.037CysAla: 1.037 ± 0.0
0.346CysCys: 0.346 ± 0.0
0.691CysAsp: 0.691 ± 0.0
0.346CysGlu: 0.346 ± 0.0
0.691CysPhe: 0.691 ± 0.0
1.382CysGly: 1.382 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.691CysIle: 0.691 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.382CysLeu: 1.382 ± 0.0
0.346CysMet: 0.346 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.382CysPro: 1.382 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.691CysArg: 0.691 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.037CysThr: 1.037 ± 0.0
2.419CysVal: 2.419 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.346CysTyr: 0.346 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.147AspAla: 4.147 ± 0.0
1.037AspCys: 1.037 ± 0.0
2.419AspAsp: 2.419 ± 0.0
4.492AspGlu: 4.492 ± 0.0
4.147AspPhe: 4.147 ± 0.0
2.419AspGly: 2.419 ± 0.0
2.419AspHis: 2.419 ± 0.0
2.764AspIle: 2.764 ± 0.0
0.0AspLys: 0.0 ± 0.0
5.529AspLeu: 5.529 ± 0.0
1.728AspMet: 1.728 ± 0.0
1.728AspAsn: 1.728 ± 0.0
3.801AspPro: 3.801 ± 0.0
1.382AspGln: 1.382 ± 0.0
2.419AspArg: 2.419 ± 0.0
4.147AspSer: 4.147 ± 0.0
4.492AspThr: 4.492 ± 0.0
5.183AspVal: 5.183 ± 0.0
0.691AspTrp: 0.691 ± 0.0
2.073AspTyr: 2.073 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.147GluAla: 4.147 ± 0.0
0.346GluCys: 0.346 ± 0.0
2.764GluAsp: 2.764 ± 0.0
3.11GluGlu: 3.11 ± 0.0
3.801GluPhe: 3.801 ± 0.0
1.037GluGly: 1.037 ± 0.0
2.073GluHis: 2.073 ± 0.0
3.801GluIle: 3.801 ± 0.0
2.073GluLys: 2.073 ± 0.0
5.529GluLeu: 5.529 ± 0.0
1.728GluMet: 1.728 ± 0.0
1.728GluAsn: 1.728 ± 0.0
4.147GluPro: 4.147 ± 0.0
2.073GluGln: 2.073 ± 0.0
3.455GluArg: 3.455 ± 0.0
5.529GluSer: 5.529 ± 0.0
0.691GluThr: 0.691 ± 0.0
2.764GluVal: 2.764 ± 0.0
0.691GluTrp: 0.691 ± 0.0
1.728GluTyr: 1.728 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.764PheAla: 2.764 ± 0.0
0.346PheCys: 0.346 ± 0.0
3.801PheAsp: 3.801 ± 0.0
2.764PheGlu: 2.764 ± 0.0
1.382PhePhe: 1.382 ± 0.0
3.11PheGly: 3.11 ± 0.0
1.037PheHis: 1.037 ± 0.0
0.691PheIle: 0.691 ± 0.0
1.037PheLys: 1.037 ± 0.0
7.602PheLeu: 7.602 ± 0.0
0.346PheMet: 0.346 ± 0.0
1.382PheAsn: 1.382 ± 0.0
2.419PhePro: 2.419 ± 0.0
2.419PheGln: 2.419 ± 0.0
3.11PheArg: 3.11 ± 0.0
4.838PheSer: 4.838 ± 0.0
2.764PheThr: 2.764 ± 0.0
3.455PheVal: 3.455 ± 0.0
1.037PheTrp: 1.037 ± 0.0
3.11PheTyr: 3.11 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.492GlyAla: 4.492 ± 0.0
1.728GlyCys: 1.728 ± 0.0
4.492GlyAsp: 4.492 ± 0.0
2.764GlyGlu: 2.764 ± 0.0
2.764GlyPhe: 2.764 ± 0.0
3.455GlyGly: 3.455 ± 0.0
2.419GlyHis: 2.419 ± 0.0
5.183GlyIle: 5.183 ± 0.0
1.728GlyLys: 1.728 ± 0.0
4.838GlyLeu: 4.838 ± 0.0
2.419GlyMet: 2.419 ± 0.0
1.728GlyAsn: 1.728 ± 0.0
1.728GlyPro: 1.728 ± 0.0
3.11GlyGln: 3.11 ± 0.0
4.838GlyArg: 4.838 ± 0.0
5.529GlySer: 5.529 ± 0.0
2.419GlyThr: 2.419 ± 0.0
3.11GlyVal: 3.11 ± 0.0
0.691GlyTrp: 0.691 ± 0.0
2.073GlyTyr: 2.073 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.728HisAla: 1.728 ± 0.0
0.346HisCys: 0.346 ± 0.0
1.728HisAsp: 1.728 ± 0.0
1.037HisGlu: 1.037 ± 0.0
1.382HisPhe: 1.382 ± 0.0
1.382HisGly: 1.382 ± 0.0
0.691HisHis: 0.691 ± 0.0
1.382HisIle: 1.382 ± 0.0
1.382HisLys: 1.382 ± 0.0
3.11HisLeu: 3.11 ± 0.0
0.346HisMet: 0.346 ± 0.0
1.037HisAsn: 1.037 ± 0.0
2.419HisPro: 2.419 ± 0.0
0.691HisGln: 0.691 ± 0.0
2.073HisArg: 2.073 ± 0.0
2.419HisSer: 2.419 ± 0.0
1.037HisThr: 1.037 ± 0.0
3.11HisVal: 3.11 ± 0.0
0.691HisTrp: 0.691 ± 0.0
0.346HisTyr: 0.346 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.11IleAla: 3.11 ± 0.0
0.0IleCys: 0.0 ± 0.0
3.11IleAsp: 3.11 ± 0.0
2.419IleGlu: 2.419 ± 0.0
3.11IlePhe: 3.11 ± 0.0
3.11IleGly: 3.11 ± 0.0
1.037IleHis: 1.037 ± 0.0
1.728IleIle: 1.728 ± 0.0
2.764IleLys: 2.764 ± 0.0
4.838IleLeu: 4.838 ± 0.0
2.073IleMet: 2.073 ± 0.0
3.801IleAsn: 3.801 ± 0.0
5.874IlePro: 5.874 ± 0.0
1.382IleGln: 1.382 ± 0.0
1.728IleArg: 1.728 ± 0.0
2.419IleSer: 2.419 ± 0.0
4.492IleThr: 4.492 ± 0.0
2.764IleVal: 2.764 ± 0.0
0.0IleTrp: 0.0 ± 0.0
2.764IleTyr: 2.764 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.419LysAla: 2.419 ± 0.0
0.346LysCys: 0.346 ± 0.0
2.419LysAsp: 2.419 ± 0.0
1.382LysGlu: 1.382 ± 0.0
0.691LysPhe: 0.691 ± 0.0
2.073LysGly: 2.073 ± 0.0
0.0LysHis: 0.0 ± 0.0
2.764LysIle: 2.764 ± 0.0
2.419LysLys: 2.419 ± 0.0
1.728LysLeu: 1.728 ± 0.0
1.037LysMet: 1.037 ± 0.0
1.382LysAsn: 1.382 ± 0.0
1.382LysPro: 1.382 ± 0.0
0.346LysGln: 0.346 ± 0.0
1.037LysArg: 1.037 ± 0.0
3.11LysSer: 3.11 ± 0.0
2.419LysThr: 2.419 ± 0.0
1.037LysVal: 1.037 ± 0.0
1.382LysTrp: 1.382 ± 0.0
1.382LysTyr: 1.382 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
7.947LeuAla: 7.947 ± 0.0
1.037LeuCys: 1.037 ± 0.0
5.529LeuAsp: 5.529 ± 0.0
8.293LeuGlu: 8.293 ± 0.0
2.419LeuPhe: 2.419 ± 0.0
2.764LeuGly: 2.764 ± 0.0
2.419LeuHis: 2.419 ± 0.0
4.147LeuIle: 4.147 ± 0.0
3.11LeuLys: 3.11 ± 0.0
8.639LeuLeu: 8.639 ± 0.0
2.073LeuMet: 2.073 ± 0.0
4.838LeuAsn: 4.838 ± 0.0
5.529LeuPro: 5.529 ± 0.0
2.073LeuGln: 2.073 ± 0.0
7.602LeuArg: 7.602 ± 0.0
6.911LeuSer: 6.911 ± 0.0
5.183LeuThr: 5.183 ± 0.0
8.984LeuVal: 8.984 ± 0.0
2.419LeuTrp: 2.419 ± 0.0
0.346LeuTyr: 0.346 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.764MetAla: 2.764 ± 0.0
0.346MetCys: 0.346 ± 0.0
2.073MetAsp: 2.073 ± 0.0
2.419MetGlu: 2.419 ± 0.0
1.382MetPhe: 1.382 ± 0.0
0.346MetGly: 0.346 ± 0.0
1.037MetHis: 1.037 ± 0.0
1.728MetIle: 1.728 ± 0.0
0.346MetLys: 0.346 ± 0.0
1.382MetLeu: 1.382 ± 0.0
0.346MetMet: 0.346 ± 0.0
0.346MetAsn: 0.346 ± 0.0
1.037MetPro: 1.037 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.037MetArg: 1.037 ± 0.0
1.728MetSer: 1.728 ± 0.0
2.764MetThr: 2.764 ± 0.0
4.492MetVal: 4.492 ± 0.0
0.346MetTrp: 0.346 ± 0.0
0.346MetTyr: 0.346 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.346AsnAla: 0.346 ± 0.0
0.691AsnCys: 0.691 ± 0.0
1.382AsnAsp: 1.382 ± 0.0
2.073AsnGlu: 2.073 ± 0.0
1.728AsnPhe: 1.728 ± 0.0
1.728AsnGly: 1.728 ± 0.0
1.728AsnHis: 1.728 ± 0.0
1.382AsnIle: 1.382 ± 0.0
1.037AsnLys: 1.037 ± 0.0
1.382AsnLeu: 1.382 ± 0.0
1.728AsnMet: 1.728 ± 0.0
0.691AsnAsn: 0.691 ± 0.0
3.11AsnPro: 3.11 ± 0.0
2.419AsnGln: 2.419 ± 0.0
1.037AsnArg: 1.037 ± 0.0
1.382AsnSer: 1.382 ± 0.0
2.764AsnThr: 2.764 ± 0.0
2.764AsnVal: 2.764 ± 0.0
1.037AsnTrp: 1.037 ± 0.0
3.801AsnTyr: 3.801 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.492ProAla: 4.492 ± 0.0
0.346ProCys: 0.346 ± 0.0
4.492ProAsp: 4.492 ± 0.0
4.492ProGlu: 4.492 ± 0.0
2.764ProPhe: 2.764 ± 0.0
3.11ProGly: 3.11 ± 0.0
1.037ProHis: 1.037 ± 0.0
3.455ProIle: 3.455 ± 0.0
2.073ProLys: 2.073 ± 0.0
6.911ProLeu: 6.911 ± 0.0
0.691ProMet: 0.691 ± 0.0
1.728ProAsn: 1.728 ± 0.0
10.712ProPro: 10.712 ± 0.0
2.764ProGln: 2.764 ± 0.0
4.147ProArg: 4.147 ± 0.0
3.801ProSer: 3.801 ± 0.0
5.874ProThr: 5.874 ± 0.0
6.565ProVal: 6.565 ± 0.0
1.382ProTrp: 1.382 ± 0.0
2.419ProTyr: 2.419 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.419GlnAla: 2.419 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.382GlnAsp: 1.382 ± 0.0
0.691GlnGlu: 0.691 ± 0.0
2.073GlnPhe: 2.073 ± 0.0
5.183GlnGly: 5.183 ± 0.0
1.382GlnHis: 1.382 ± 0.0
2.419GlnIle: 2.419 ± 0.0
1.382GlnLys: 1.382 ± 0.0
1.728GlnLeu: 1.728 ± 0.0
0.346GlnMet: 0.346 ± 0.0
1.728GlnAsn: 1.728 ± 0.0
1.037GlnPro: 1.037 ± 0.0
1.382GlnGln: 1.382 ± 0.0
0.691GlnArg: 0.691 ± 0.0
2.419GlnSer: 2.419 ± 0.0
1.728GlnThr: 1.728 ± 0.0
2.419GlnVal: 2.419 ± 0.0
1.037GlnTrp: 1.037 ± 0.0
1.382GlnTyr: 1.382 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.11ArgAla: 3.11 ± 0.0
1.382ArgCys: 1.382 ± 0.0
6.22ArgAsp: 6.22 ± 0.0
1.382ArgGlu: 1.382 ± 0.0
3.11ArgPhe: 3.11 ± 0.0
3.11ArgGly: 3.11 ± 0.0
0.691ArgHis: 0.691 ± 0.0
2.419ArgIle: 2.419 ± 0.0
1.382ArgLys: 1.382 ± 0.0
7.256ArgLeu: 7.256 ± 0.0
2.073ArgMet: 2.073 ± 0.0
1.037ArgAsn: 1.037 ± 0.0
5.529ArgPro: 5.529 ± 0.0
1.382ArgGln: 1.382 ± 0.0
4.147ArgArg: 4.147 ± 0.0
5.874ArgSer: 5.874 ± 0.0
2.764ArgThr: 2.764 ± 0.0
3.11ArgVal: 3.11 ± 0.0
1.728ArgTrp: 1.728 ± 0.0
1.037ArgTyr: 1.037 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.147SerAla: 4.147 ± 0.0
1.382SerCys: 1.382 ± 0.0
4.492SerAsp: 4.492 ± 0.0
5.874SerGlu: 5.874 ± 0.0
3.455SerPhe: 3.455 ± 0.0
6.911SerGly: 6.911 ± 0.0
1.037SerHis: 1.037 ± 0.0
3.801SerIle: 3.801 ± 0.0
2.073SerLys: 2.073 ± 0.0
5.874SerLeu: 5.874 ± 0.0
3.11SerMet: 3.11 ± 0.0
3.11SerAsn: 3.11 ± 0.0
4.147SerPro: 4.147 ± 0.0
1.728SerGln: 1.728 ± 0.0
2.419SerArg: 2.419 ± 0.0
5.874SerSer: 5.874 ± 0.0
3.455SerThr: 3.455 ± 0.0
8.639SerVal: 8.639 ± 0.0
0.691SerTrp: 0.691 ± 0.0
2.764SerTyr: 2.764 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.764ThrAla: 2.764 ± 0.0
0.691ThrCys: 0.691 ± 0.0
1.728ThrAsp: 1.728 ± 0.0
1.728ThrGlu: 1.728 ± 0.0
4.147ThrPhe: 4.147 ± 0.0
4.838ThrGly: 4.838 ± 0.0
1.382ThrHis: 1.382 ± 0.0
5.529ThrIle: 5.529 ± 0.0
1.382ThrLys: 1.382 ± 0.0
4.838ThrLeu: 4.838 ± 0.0
0.691ThrMet: 0.691 ± 0.0
0.691ThrAsn: 0.691 ± 0.0
4.147ThrPro: 4.147 ± 0.0
2.419ThrGln: 2.419 ± 0.0
3.455ThrArg: 3.455 ± 0.0
6.22ThrSer: 6.22 ± 0.0
5.529ThrThr: 5.529 ± 0.0
6.22ThrVal: 6.22 ± 0.0
0.346ThrTrp: 0.346 ± 0.0
2.073ThrTyr: 2.073 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
9.675ValAla: 9.675 ± 0.0
0.691ValCys: 0.691 ± 0.0
3.11ValAsp: 3.11 ± 0.0
3.801ValGlu: 3.801 ± 0.0
2.764ValPhe: 2.764 ± 0.0
6.911ValGly: 6.911 ± 0.0
2.073ValHis: 2.073 ± 0.0
3.455ValIle: 3.455 ± 0.0
2.764ValLys: 2.764 ± 0.0
8.293ValLeu: 8.293 ± 0.0
1.728ValMet: 1.728 ± 0.0
2.419ValAsn: 2.419 ± 0.0
5.183ValPro: 5.183 ± 0.0
2.764ValGln: 2.764 ± 0.0
4.838ValArg: 4.838 ± 0.0
4.838ValSer: 4.838 ± 0.0
2.764ValThr: 2.764 ± 0.0
4.492ValVal: 4.492 ± 0.0
1.728ValTrp: 1.728 ± 0.0
4.147ValTyr: 4.147 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.037TrpAla: 1.037 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.691TrpAsp: 0.691 ± 0.0
1.037TrpGlu: 1.037 ± 0.0
1.382TrpPhe: 1.382 ± 0.0
0.346TrpGly: 0.346 ± 0.0
1.037TrpHis: 1.037 ± 0.0
1.382TrpIle: 1.382 ± 0.0
1.728TrpLys: 1.728 ± 0.0
1.037TrpLeu: 1.037 ± 0.0
0.346TrpMet: 0.346 ± 0.0
0.346TrpAsn: 0.346 ± 0.0
1.037TrpPro: 1.037 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.728TrpArg: 1.728 ± 0.0
1.037TrpSer: 1.037 ± 0.0
2.419TrpThr: 2.419 ± 0.0
0.691TrpVal: 0.691 ± 0.0
1.037TrpTrp: 1.037 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.728TyrAla: 1.728 ± 0.0
0.691TyrCys: 0.691 ± 0.0
2.419TyrAsp: 2.419 ± 0.0
1.037TyrGlu: 1.037 ± 0.0
2.073TyrPhe: 2.073 ± 0.0
2.764TyrGly: 2.764 ± 0.0
2.073TyrHis: 2.073 ± 0.0
1.037TyrIle: 1.037 ± 0.0
0.691TyrLys: 0.691 ± 0.0
3.801TyrLeu: 3.801 ± 0.0
0.346TyrMet: 0.346 ± 0.0
1.382TyrAsn: 1.382 ± 0.0
3.11TyrPro: 3.11 ± 0.0
1.382TyrGln: 1.382 ± 0.0
2.419TyrArg: 2.419 ± 0.0
1.037TyrSer: 1.037 ± 0.0
2.419TyrThr: 2.419 ± 0.0
3.11TyrVal: 3.11 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.419TyrTyr: 2.419 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2895 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski