Amino acid dipepetide frequency for Ulvibacter marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.707AlaAla: 4.707 ± 0.081	0.538AlaCys: 0.538 ± 0.027	3.327AlaAsp: 3.327 ± 0.055	4.133AlaGlu: 4.133 ± 0.067	3.304AlaPhe: 3.304 ± 0.065	4.302AlaGly: 4.302 ± 0.09	1.07AlaHis: 1.07 ± 0.035	5.897AlaIle: 5.897 ± 0.08	4.5AlaLys: 4.5 ± 0.083	6.427AlaLeu: 6.427 ± 0.094	1.597AlaMet: 1.597 ± 0.045	3.639AlaAsn: 3.639 ± 0.069	2.035AlaPro: 2.035 ± 0.051	2.478AlaGln: 2.478 ± 0.053	2.069AlaArg: 2.069 ± 0.045	4.41AlaSer: 4.41 ± 0.08	4.258AlaThr: 4.258 ± 0.075	4.237AlaVal: 4.237 ± 0.069	0.548AlaTrp: 0.548 ± 0.03	2.474AlaTyr: 2.474 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.45CysAla: 0.45 ± 0.023	0.096CysCys: 0.096 ± 0.01	0.51CysAsp: 0.51 ± 0.028	0.488CysGlu: 0.488 ± 0.023	0.372CysPhe: 0.372 ± 0.022	0.619CysGly: 0.619 ± 0.027	0.154CysHis: 0.154 ± 0.014	0.531CysIle: 0.531 ± 0.02	0.421CysLys: 0.421 ± 0.019	0.604CysLeu: 0.604 ± 0.022	0.128CysMet: 0.128 ± 0.012	0.443CysAsn: 0.443 ± 0.024	0.334CysPro: 0.334 ± 0.023	0.211CysGln: 0.211 ± 0.018	0.17CysArg: 0.17 ± 0.013	0.551CysSer: 0.551 ± 0.029	0.446CysThr: 0.446 ± 0.028	0.451CysVal: 0.451 ± 0.02	0.061CysTrp: 0.061 ± 0.008	0.294CysTyr: 0.294 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.994AspAla: 3.994 ± 0.065	0.489AspCys: 0.489 ± 0.03	3.295AspAsp: 3.295 ± 0.066	3.712AspGlu: 3.712 ± 0.064	3.546AspPhe: 3.546 ± 0.068	4.212AspGly: 4.212 ± 0.077	0.878AspHis: 0.878 ± 0.032	4.552AspIle: 4.552 ± 0.067	3.797AspLys: 3.797 ± 0.071	4.975AspLeu: 4.975 ± 0.077	1.115AspMet: 1.115 ± 0.03	3.418AspAsn: 3.418 ± 0.069	1.846AspPro: 1.846 ± 0.055	1.523AspGln: 1.523 ± 0.04	1.827AspArg: 1.827 ± 0.049	3.377AspSer: 3.377 ± 0.068	3.217AspThr: 3.217 ± 0.072	4.087AspVal: 4.087 ± 0.082	0.697AspTrp: 0.697 ± 0.027	2.691AspTyr: 2.691 ± 0.061	0.0AspXaa: 0.0 ± 0.0
Glu	4.572GluAla: 4.572 ± 0.075	0.354GluCys: 0.354 ± 0.02	3.692GluAsp: 3.692 ± 0.071	4.799GluGlu: 4.799 ± 0.096	2.854GluPhe: 2.854 ± 0.052	3.874GluGly: 3.874 ± 0.072	1.131GluHis: 1.131 ± 0.035	5.878GluIle: 5.878 ± 0.087	5.322GluLys: 5.322 ± 0.092	6.005GluLeu: 6.005 ± 0.083	1.757GluMet: 1.757 ± 0.045	4.894GluAsn: 4.894 ± 0.078	1.522GluPro: 1.522 ± 0.039	2.369GluGln: 2.369 ± 0.056	2.534GluArg: 2.534 ± 0.057	3.418GluSer: 3.418 ± 0.05	4.195GluThr: 4.195 ± 0.06	4.381GluVal: 4.381 ± 0.076	0.558GluTrp: 0.558 ± 0.023	2.422GluTyr: 2.422 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	2.935PheAla: 2.935 ± 0.06	0.39PheCys: 0.39 ± 0.02	3.404PheAsp: 3.404 ± 0.063	3.547PheGlu: 3.547 ± 0.058	2.553PhePhe: 2.553 ± 0.061	3.546PheGly: 3.546 ± 0.079	0.749PheHis: 0.749 ± 0.03	3.866PheIle: 3.866 ± 0.079	3.78PheLys: 3.78 ± 0.068	4.308PheLeu: 4.308 ± 0.071	1.031PheMet: 1.031 ± 0.03	3.472PheAsn: 3.472 ± 0.075	1.732PhePro: 1.732 ± 0.042	1.522PheGln: 1.522 ± 0.042	1.503PheArg: 1.503 ± 0.035	3.929PheSer: 3.929 ± 0.067	3.339PheThr: 3.339 ± 0.06	3.107PheVal: 3.107 ± 0.061	0.506PheTrp: 0.506 ± 0.022	2.065PheTyr: 2.065 ± 0.05	0.0PheXaa: 0.0 ± 0.0
Gly	4.414GlyAla: 4.414 ± 0.089	0.541GlyCys: 0.541 ± 0.025	3.774GlyAsp: 3.774 ± 0.078	3.65GlyGlu: 3.65 ± 0.062	3.629GlyPhe: 3.629 ± 0.056	4.792GlyGly: 4.792 ± 0.118	1.073GlyHis: 1.073 ± 0.033	5.363GlyIle: 5.363 ± 0.085	4.329GlyLys: 4.329 ± 0.069	5.739GlyLeu: 5.739 ± 0.079	1.636GlyMet: 1.636 ± 0.047	3.911GlyAsn: 3.911 ± 0.072	1.354GlyPro: 1.354 ± 0.034	1.895GlyGln: 1.895 ± 0.049	2.111GlyArg: 2.111 ± 0.051	4.019GlySer: 4.019 ± 0.077	4.462GlyThr: 4.462 ± 0.1	4.561GlyVal: 4.561 ± 0.07	0.659GlyTrp: 0.659 ± 0.028	2.688GlyTyr: 2.688 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	0.825HisAla: 0.825 ± 0.028	0.172HisCys: 0.172 ± 0.012	0.741HisAsp: 0.741 ± 0.028	0.837HisGlu: 0.837 ± 0.032	1.074HisPhe: 1.074 ± 0.034	0.94HisGly: 0.94 ± 0.033	0.404HisHis: 0.404 ± 0.024	1.391HisIle: 1.391 ± 0.038	1.195HisLys: 1.195 ± 0.039	1.744HisLeu: 1.744 ± 0.044	0.3HisMet: 0.3 ± 0.017	0.966HisAsn: 0.966 ± 0.029	0.823HisPro: 0.823 ± 0.03	0.623HisGln: 0.623 ± 0.025	0.62HisArg: 0.62 ± 0.025	1.011HisSer: 1.011 ± 0.036	1.033HisThr: 1.033 ± 0.031	0.817HisVal: 0.817 ± 0.027	0.196HisTrp: 0.196 ± 0.013	0.756HisTyr: 0.756 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.032IleAla: 6.032 ± 0.088	0.591IleCys: 0.591 ± 0.026	5.22IleAsp: 5.22 ± 0.076	5.692IleGlu: 5.692 ± 0.08	3.55IlePhe: 3.55 ± 0.071	4.951IleGly: 4.951 ± 0.077	1.219IleHis: 1.219 ± 0.037	5.989IleIle: 5.989 ± 0.095	5.623IleLys: 5.623 ± 0.076	6.984IleLeu: 6.984 ± 0.1	1.298IleMet: 1.298 ± 0.039	4.869IleAsn: 4.869 ± 0.087	3.305IlePro: 3.305 ± 0.058	2.338IleGln: 2.338 ± 0.049	2.416IleArg: 2.416 ± 0.051	6.279IleSer: 6.279 ± 0.094	5.323IleThr: 5.323 ± 0.09	4.993IleVal: 4.993 ± 0.078	0.659IleTrp: 0.659 ± 0.026	2.717IleTyr: 2.717 ± 0.057	0.0IleXaa: 0.0 ± 0.0
Lys	4.769LysAla: 4.769 ± 0.077	0.317LysCys: 0.317 ± 0.017	4.216LysAsp: 4.216 ± 0.071	5.73LysGlu: 5.73 ± 0.096	2.857LysPhe: 2.857 ± 0.058	4.296LysGly: 4.296 ± 0.08	1.316LysHis: 1.316 ± 0.032	5.769LysIle: 5.769 ± 0.093	6.544LysLys: 6.544 ± 0.123	6.3LysLeu: 6.3 ± 0.098	2.08LysMet: 2.08 ± 0.052	4.981LysAsn: 4.981 ± 0.083	2.168LysPro: 2.168 ± 0.051	2.701LysGln: 2.701 ± 0.054	2.775LysArg: 2.775 ± 0.06	4.262LysSer: 4.262 ± 0.079	4.543LysThr: 4.543 ± 0.079	4.44LysVal: 4.44 ± 0.081	0.683LysTrp: 0.683 ± 0.029	2.783LysTyr: 2.783 ± 0.052	0.0LysXaa: 0.0 ± 0.0
Leu	5.778LeuAla: 5.778 ± 0.091	0.587LeuCys: 0.587 ± 0.027	5.339LeuAsp: 5.339 ± 0.072	6.167LeuGlu: 6.167 ± 0.093	4.777LeuPhe: 4.777 ± 0.08	5.919LeuGly: 5.919 ± 0.085	1.412LeuHis: 1.412 ± 0.038	6.998LeuIle: 6.998 ± 0.082	7.55LeuLys: 7.55 ± 0.116	8.883LeuLeu: 8.883 ± 0.12	2.011LeuMet: 2.011 ± 0.049	5.634LeuAsn: 5.634 ± 0.079	3.309LeuPro: 3.309 ± 0.064	3.162LeuGln: 3.162 ± 0.062	3.098LeuArg: 3.098 ± 0.055	6.342LeuSer: 6.342 ± 0.082	5.148LeuThr: 5.148 ± 0.077	5.447LeuVal: 5.447 ± 0.077	0.732LeuTrp: 0.732 ± 0.027	3.051LeuTyr: 3.051 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	1.641MetAla: 1.641 ± 0.047	0.137MetCys: 0.137 ± 0.012	1.205MetAsp: 1.205 ± 0.034	1.382MetGlu: 1.382 ± 0.038	0.864MetPhe: 0.864 ± 0.038	1.436MetGly: 1.436 ± 0.044	0.364MetHis: 0.364 ± 0.019	1.528MetIle: 1.528 ± 0.037	2.158MetLys: 2.158 ± 0.052	2.034MetLeu: 2.034 ± 0.05	0.597MetMet: 0.597 ± 0.025	1.251MetAsn: 1.251 ± 0.037	0.862MetPro: 0.862 ± 0.034	0.771MetGln: 0.771 ± 0.028	0.844MetArg: 0.844 ± 0.032	1.494MetSer: 1.494 ± 0.037	1.191MetThr: 1.191 ± 0.033	1.365MetVal: 1.365 ± 0.041	0.159MetTrp: 0.159 ± 0.012	0.744MetTyr: 0.744 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	4.091AsnAla: 4.091 ± 0.07	0.496AsnCys: 0.496 ± 0.03	3.571AsnAsp: 3.571 ± 0.069	4.038AsnGlu: 4.038 ± 0.057	3.159AsnPhe: 3.159 ± 0.058	4.263AsnGly: 4.263 ± 0.076	1.038AsnHis: 1.038 ± 0.028	4.917AsnIle: 4.917 ± 0.072	4.11AsnLys: 4.11 ± 0.074	5.187AsnLeu: 5.187 ± 0.076	1.292AsnMet: 1.292 ± 0.038	4.204AsnAsn: 4.204 ± 0.089	2.833AsnPro: 2.833 ± 0.058	2.132AsnGln: 2.132 ± 0.052	2.122AsnArg: 2.122 ± 0.058	4.028AsnSer: 4.028 ± 0.073	4.156AsnThr: 4.156 ± 0.094	3.784AsnVal: 3.784 ± 0.07	0.726AsnTrp: 0.726 ± 0.03	2.771AsnTyr: 2.771 ± 0.058	0.0AsnXaa: 0.0 ± 0.0
Pro	1.999ProAla: 1.999 ± 0.051	0.233ProCys: 0.233 ± 0.017	1.983ProAsp: 1.983 ± 0.039	2.647ProGlu: 2.647 ± 0.052	1.952ProPhe: 1.952 ± 0.044	1.86ProGly: 1.86 ± 0.045	0.561ProHis: 0.561 ± 0.024	2.628ProIle: 2.628 ± 0.053	2.459ProLys: 2.459 ± 0.054	3.057ProLeu: 3.057 ± 0.063	0.685ProMet: 0.685 ± 0.027	2.252ProAsn: 2.252 ± 0.052	0.829ProPro: 0.829 ± 0.033	1.2ProGln: 1.2 ± 0.036	0.892ProArg: 0.892 ± 0.032	2.321ProSer: 2.321 ± 0.055	2.036ProThr: 2.036 ± 0.044	2.317ProVal: 2.317 ± 0.047	0.299ProTrp: 0.299 ± 0.018	1.331ProTyr: 1.331 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	2.038GlnAla: 2.038 ± 0.047	0.182GlnCys: 0.182 ± 0.013	1.731GlnAsp: 1.731 ± 0.039	2.393GlnGlu: 2.393 ± 0.053	1.728GlnPhe: 1.728 ± 0.039	1.877GlnGly: 1.877 ± 0.047	0.596GlnHis: 0.596 ± 0.024	2.478GlnIle: 2.478 ± 0.048	2.54GlnLys: 2.54 ± 0.052	3.578GlnLeu: 3.578 ± 0.069	0.819GlnMet: 0.819 ± 0.028	2.049GlnAsn: 2.049 ± 0.044	1.032GlnPro: 1.032 ± 0.036	1.402GlnGln: 1.402 ± 0.045	1.257GlnArg: 1.257 ± 0.038	1.92GlnSer: 1.92 ± 0.044	1.893GlnThr: 1.893 ± 0.043	2.042GlnVal: 2.042 ± 0.044	0.358GlnTrp: 0.358 ± 0.019	1.296GlnTyr: 1.296 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.125ArgAla: 2.125 ± 0.048	0.177ArgCys: 0.177 ± 0.015	1.936ArgAsp: 1.936 ± 0.046	2.198ArgGlu: 2.198 ± 0.046	1.817ArgPhe: 1.817 ± 0.046	1.922ArgGly: 1.922 ± 0.05	0.553ArgHis: 0.553 ± 0.023	2.777ArgIle: 2.777 ± 0.056	2.626ArgLys: 2.626 ± 0.054	3.046ArgLeu: 3.046 ± 0.055	0.869ArgMet: 0.869 ± 0.032	2.173ArgAsn: 2.173 ± 0.046	1.05ArgPro: 1.05 ± 0.036	1.055ArgGln: 1.055 ± 0.038	1.26ArgArg: 1.26 ± 0.037	1.894ArgSer: 1.894 ± 0.049	1.879ArgThr: 1.879 ± 0.046	2.101ArgVal: 2.101 ± 0.049	0.33ArgTrp: 0.33 ± 0.019	1.465ArgTyr: 1.465 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	3.949SerAla: 3.949 ± 0.058	0.659SerCys: 0.659 ± 0.029	3.361SerAsp: 3.361 ± 0.047	4.306SerGlu: 4.306 ± 0.064	3.754SerPhe: 3.754 ± 0.062	4.554SerGly: 4.554 ± 0.082	1.026SerHis: 1.026 ± 0.032	5.553SerIle: 5.553 ± 0.084	4.801SerLys: 4.801 ± 0.08	6.112SerLeu: 6.112 ± 0.087	1.352SerMet: 1.352 ± 0.045	4.086SerAsn: 4.086 ± 0.072	2.111SerPro: 2.111 ± 0.05	2.247SerGln: 2.247 ± 0.052	2.134SerArg: 2.134 ± 0.054	4.325SerSer: 4.325 ± 0.083	3.949SerThr: 3.949 ± 0.077	4.146SerVal: 4.146 ± 0.068	0.682SerTrp: 0.682 ± 0.024	2.633SerTyr: 2.633 ± 0.061	0.0SerXaa: 0.0 ± 0.0
Thr	4.211ThrAla: 4.211 ± 0.078	0.437ThrCys: 0.437 ± 0.026	3.393ThrAsp: 3.393 ± 0.082	3.916ThrGlu: 3.916 ± 0.061	3.258ThrPhe: 3.258 ± 0.056	4.208ThrGly: 4.208 ± 0.089	1.044ThrHis: 1.044 ± 0.034	5.453ThrIle: 5.453 ± 0.084	3.964ThrLys: 3.964 ± 0.068	5.741ThrLeu: 5.741 ± 0.069	1.1ThrMet: 1.1 ± 0.034	3.762ThrAsn: 3.762 ± 0.074	2.624ThrPro: 2.624 ± 0.055	2.009ThrGln: 2.009 ± 0.044	1.708ThrArg: 1.708 ± 0.045	4.216ThrSer: 4.216 ± 0.078	4.342ThrThr: 4.342 ± 0.091	4.187ThrVal: 4.187 ± 0.088	0.564ThrTrp: 0.564 ± 0.028	2.448ThrTyr: 2.448 ± 0.057	0.0ThrXaa: 0.0 ± 0.0
Val	4.51ValAla: 4.51 ± 0.072	0.545ValCys: 0.545 ± 0.023	3.723ValAsp: 3.723 ± 0.058	4.013ValGlu: 4.013 ± 0.07	3.404ValPhe: 3.404 ± 0.068	3.896ValGly: 3.896 ± 0.068	0.963ValHis: 0.963 ± 0.034	4.994ValIle: 4.994 ± 0.084	4.165ValLys: 4.165 ± 0.069	6.086ValLeu: 6.086 ± 0.087	1.361ValMet: 1.361 ± 0.039	3.586ValAsn: 3.586 ± 0.063	2.165ValPro: 2.165 ± 0.051	1.87ValGln: 1.87 ± 0.047	1.976ValArg: 1.976 ± 0.051	4.784ValSer: 4.784 ± 0.063	4.226ValThr: 4.226 ± 0.112	4.477ValVal: 4.477 ± 0.082	0.602ValTrp: 0.602 ± 0.024	2.359ValTyr: 2.359 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.552TrpAla: 0.552 ± 0.023	0.092TrpCys: 0.092 ± 0.01	0.581TrpAsp: 0.581 ± 0.026	0.637TrpGlu: 0.637 ± 0.029	0.536TrpPhe: 0.536 ± 0.024	0.584TrpGly: 0.584 ± 0.027	0.196TrpHis: 0.196 ± 0.015	0.701TrpIle: 0.701 ± 0.027	0.715TrpLys: 0.715 ± 0.027	0.848TrpLeu: 0.848 ± 0.032	0.308TrpMet: 0.308 ± 0.017	0.624TrpAsn: 0.624 ± 0.026	0.209TrpPro: 0.209 ± 0.015	0.363TrpGln: 0.363 ± 0.019	0.371TrpArg: 0.371 ± 0.021	0.552TrpSer: 0.552 ± 0.025	0.513TrpThr: 0.513 ± 0.023	0.587TrpVal: 0.587 ± 0.024	0.117TrpTrp: 0.117 ± 0.012	0.432TrpTyr: 0.432 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.356TyrAla: 2.356 ± 0.05	0.298TyrCys: 0.298 ± 0.018	2.246TyrAsp: 2.246 ± 0.051	2.245TyrGlu: 2.245 ± 0.05	2.294TyrPhe: 2.294 ± 0.051	2.553TyrGly: 2.553 ± 0.061	0.722TyrHis: 0.722 ± 0.028	2.788TyrIle: 2.788 ± 0.058	2.931TyrLys: 2.931 ± 0.056	3.685TyrLeu: 3.685 ± 0.066	0.693TyrMet: 0.693 ± 0.022	2.703TyrAsn: 2.703 ± 0.059	1.398TyrPro: 1.398 ± 0.038	1.341TyrGln: 1.341 ± 0.035	1.565TyrArg: 1.565 ± 0.041	2.609TyrSer: 2.609 ± 0.059	2.435TyrThr: 2.435 ± 0.053	2.177TyrVal: 2.177 ± 0.046	0.383TyrTrp: 0.383 ± 0.019	1.747TyrTyr: 1.747 ± 0.049	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3169 proteins (1055359 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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